Building Muscle Can Lower Person’s Risk of Insulin Resistance Increased Muscle Mass May Lower Risk of Pre-Diabetes
ScienceDaily (July 28, 2011) — A recent study accepted for publication in The Endocrine Society’s Journal of Clinical Endocrinology & Metabolism(JCEM) found that the greater an individual’s total muscle mass, the lower the person’s risk of having insulin resistance, the major precursor of type 2 diabetes.—-With recent dramatic increases in obesity worldwide, the prevalence of diabetes, a major source of cardiovascular morbidity, is expected to accelerate. Insulin resistance, which can raise blood glucose levels above the normal range, is a major factor that contributes to the development of diabetes. Previous studies have shown that very low muscle mass is a risk factor for insulin resistance, but until now, no study has examined whether increasing muscle mass to average and above average levels, independent of obesity levels, would lead to improved blood glucose regulation.—“Our findings represent a departure from the usual focus of clinicians, and their patients, on just losing weight to improve metabolic health,” said the study’s senior author, Preethi Srikanthan, MD, of the University of California, Los Angeles (UCLA). “Instead, this research suggests a role for maintaining fitness and building muscle. This is a welcome message for many overweight patients who experience difficulty in achieving weight loss, as any effort to get moving and keep fit should be seen as laudable and contributing to metabolic change.”—-In this study, researchers examined the association of skeletal muscle mass with insulin resistance and blood glucose metabolism disorders in a nationally representative sample of 13,644 individuals. Participants were older than 20 years, non-pregnant and weighed more than 35 kg. The study demonstrated that higher muscle mass (relative to body size) is associated with better insulin sensitivity and lower risk of pre- or overt diabetes.—-“Our research shows that beyond monitoring changes in waist circumference or BMI, we should also be monitoring muscle mass,” Srikanthan concluded. “Further research is needed to determine the nature and duration of exercise interventions required to improve insulin sensitivity and glucose metabolism in at-risk individuals.”—Also working on the study was Arun Karlamangla, PhD, MD, of the David Geffen School of Medicine at UCLA.–Story Source-The above story is reprinted (with editorial adaptations by ScienceDaily staff) from materials provided by The Endocrine Society, viaEurekAlert!, a service of AAAS.–Journal Reference-P. Srikanthan, A. S. Karlamangla. Relative Muscle Mass Is Inversely Associated with Insulin Resistance and Prediabetes. Findings from The Third National Health and Nutrition Examination Survey. Journal of Clinical Endocrinology & Metabolism, 2011; DOI: 10.1210/jc.2011-0435
New Target Found for Nitric Oxide’s Attack On Salmonella Bacteria
ScienceDaily (July 23, 2011) — A new target for nitric oxide has been revealed in studies of how it inhibits the growth of Salmonella. This bacterium is a common cause of food-poisoning.—“Nitric oxide is naturally produced in the nose and the gut and other tissues in the body to ward off infection,” explained the senior author of the paper, Dr. Ferric Fang. He is a University of Washington (UW) professor of laboratory medicine, microbiology and medicine.–Nitric oxide — not to be confused with nitrous oxide, the laughing gas in dentists’ offices — is similar to the preservatives in hotdogs, Fang said. Reactive nitrogen species, like nitric oxide, make brown meat an appetizing pink. They also weed out microorganisms that spoil food or cause food poisoning.—Fang’s lab has made several important discoveries on ways mammals exploit the biochemical properties of nitric oxide to defend themselves from germs. Nitric oxide, a key actor in the body’s innate immune defenses, apprehends a rogue’s gallery of disease-causing organisms.
The newest results underscore that nitric oxide’s antimicrobial actions are due to its interference with the metabolism, or energy production, of pathogens.—“Nitric oxide imposes substantial metabolic restrictions on bacteria,” the researchers noted. Fang explained that its reactions with numerous metabolic targets accounts for the broad-spectrum nature of its success. It keeps many types of disease-causing bacteria at bay. It also prevents an overgrowth of the body’s many helpful bacteria.—The latest report on the versatility of nitric oxide in arming hosts against pathogens is published in the July 21 issue of Cell Host & Microbe. Dr. Anthony R. Richardson, who is now at the University of North Carolina at Chapel Hill, led the research while he was a postdoctoral fellow in the Fang lab. –Fang’s team looked at the multi-pronged action of nitric oxide on Salmonella enterica serovar Typhimurium. This type of Salmonella can contaminate food and is similar to the bacteria that cause typhoid fever.–Nitric oxide and related chemicals put Salmonella into a difficult situation called nitrosative stress. When exposed to nitric oxide, Salmonella is unable to make two essential amino acids, methionine and lysine.—-Without these, Salmonella cannot grow.—“This is bad news for the bacteria, but not for the host,” Fang said. “Nitric oxide doesn’t damage the host that produces it.”–
The ability to withstand nitrosative stress makes some forms of bacteria more virulent than milder types that can’t handle it.—Richardson and his colleagues found that nitric oxide and its cousins throw a monkey wrench into several points in the Krebs cycle, also known as the tricarboxylic acid cycle. This cycle is the second stage in cellular respiration, when fuel is broken down to release energy for cell growth and division.—The researchers outlined how multiple interruptions in this cycle create a series of biochemical consequences that starve Salmonella of methionine and lysine. Nitric oxide also blocks certain regulatory genes that otherwise would give Salmonella an alternate chemical route out of its distress.–“Collectively, this work demonstrates that nitric oxide imposes substantial metabolic restrictions on bacteria,” the authors concluded.—In a commentary on these findings, Dr. Stephen Spiro of the Department of Molecular and Cell Biology at the University of Texas at Dallas wrote that the work “focuses renewed interest in central metabolic pathways as nitric oxide targets.”-“More generally,” he noted, “this study provides an excellent illustration that a proper understanding of host-pathogen interactions and the development of therapeutic interventions require a detailed knowledge of pathogen metabolism.”—Nitric oxide’s targeting of the Krebs cycle is not unique to Salmonella. In learning how the body naturally controls the energy supplies and growth of varied disease-causing organisms, Fang said, scientists may be able to develop new broad-spectrum antimicrobials that mimic these effects[U5], drugs that promote the body’s own natural defenses against infection, or agents that overcome the ways virulent bacteria compensate when being starved of certain nutrients.—The research was supported by grants from the National Institutes of Health.–Story Source:–The above story is reprinted (with editorial adaptations by ScienceDaily staff) from materials provided by University of Washington. The original article was written by Leila Gray.—Journal Reference-Anthony R. Richardson, Elizabeth C. Payne, Noah Younger, Joyce E. Karlinsey, Vinai C. Thomas, Lynne A. Becker, William W. Navarre, Margaret E. Castor, Stephen J. Libby, Ferric C. Fang. Multiple Targets of Nitric Oxide in the Tricarboxylic Acid Cycle of Salmonella enterica Serovar Typhimurium. Cell Host & Microbe, 21 July 2011; 10(1) pp. 33 – 43 DOI: 10.1016/j.chom.2011.06.004
[U1]GEO Manipulation of DNA and Genetics causing the impbalance
[U2]It appears they do not like water and a mature forest which would hold water and other anti bacterial elements that a forest fully matured would have developed
[U3]Another rogue Military experiment Perhaps—to release pathogens and infections- Bio genetics ?
[U4]Again Military Experimentation???
[U5]In other words Natural methods are effective and the Drug industry has not yet understood the means of creating or mimicking there efficiency or effectiveness
Show of the Week August 15 2011
List of High-Protein Foods and Amount of Protein in Each
Foods High in Protein–Dry Measure Equivalents
Wafting poison makes fertile ground for suit in Stearns County
Peanuts—Black Seed- Nobileton-Rosemary-
Recipe for a Peanut Butter Delight
People who crave Sodium (Salt) are often found to be suffering from Adrenal Insufficiency.
Sodium increases the viscosity (thickness) of Blood.
Sodium may help to regulate osmotic Blood Pressure:
Caution: excess Sodium may increase Blood Pressure.
Sodium may alleviate Hypotension
60% of the body’s stored Sodium is in the fluids surrounding the Cells (extracellular) and 10% concentrates inside the body’s Cells (in the Intracellular Fluid):
-Sodium is the principal anion (negatively-charged Ion) in the Intracellular Fluid.
Sodium may reverse Acidosis.
Sodium is one of the body’s primary Electrolytes.
Sodium may alleviate Constipation.
Sodium Sulfate may alleviate Diarrhea.
Flatulence may occur as a result of Sodium deficiency.
Nausea may occur as a result of Sodium deficiency
Vomiting may occur as a result of Sodium deficiency.
Optimal (but not excessive) Sodium levels are required for the correct function of the Kidneys.
Sodium deficiency may cause Blurred Vision.
Sodium may help to reduce Fevers.
Optimal Sodium levels are required for the correct function of the Lymphatic System (Sodium is a component of Lymph). [more info]
30% of the body’s Sodium concentrates in the Bones.
Correct Potassium:Sodium balance is essential for the correct function of the
Muscles—-Shrinkage of the Muscles can occur as a result of Sodium deficiency.
Sodium may facilitate proper Muscle contraction. [more info]
Muscle Cramps may occur as a result of Sodium deficiency.
Apathy may occur as a result of Sodium deficiency.
Impaired Concentration ability may occur as a result of Sodium deficiency.
Confusion may occur as a result of Sodium deficiency
Severe Sodium deficiency may cause Hallucinations.
Memory impairment may occur as a result of Sodium deficiency.
Sodium may facilitate the conduction of Nerve Impulses in the Cell Membranes of the Nervous System
Sodium may alleviate Heat Stroke.
Water & Water Balance
Sodium may alleviate Dehydration (by facilitating the retention of Water). Sodium regulates the body’s Water Balance (by causing the retention of Water) – Sodium helps to maintain a normal balance of Water between the body’s Cells and surrounding fluids:
List of High-Protein Foods and Amount of Protein in Each
Foods High in Protein
Shortcut: An ounce of meat or fish has approximately 7 grams of protein.
Hamburger patty, 3 oz – 28 grams protein
Steak, 4 oz – 42 grams
Most cuts of beef – 9 grams of protein per ounce
Chicken breast, 3.5 oz – 30 grams protein
Chicken thigh – 10 grams (for average size)
Drumstick – 11 grams
Wing – 6 grams
Chicken meat, cooked, 3 oz – 35 grams
Most fish fillets or steaks are about 22 grams of protein for 3 ½ oz (100 grams) of cooked fish, or 6 grams per ounce About 20 grams per 3 oz
Tuna, 6 oz can – 40 grams of protein
Pork chop, average – 22 grams protein
Pork loin or tenderloin, 4 oz – 29 grams
Ham, 3 oz serving – 19 grams
Ground pork, 1 oz raw – 5 grams; 3 oz cooked – 22 grams
Bacon, 1 slice – 3 grams
Canadian-style bacon (back bacon), slice – 5 – 6 grams
Eggs and Dairy
Egg, large – 6 grams protein
Milk, 1 cup – 8 grams
Cottage cheese, ½ cup – 15 grams
Yogurt, 1 cup – usually 8-12 grams, check label
Soft cheeses (Mozzarella, Brie, Camembert) – 6 grams per oz
Medium cheeses (Cheddar, Swiss) – 7 or 8 grams per oz
Hard cheeses (Parmesan) – 10 grams per oz
Nuts and Seeds
Peanut butter, 2 Tablespoons – 8 grams protein
Almonds, ¼ cup – 8 grams
Peanuts, ¼ cup – 9 grams
Cashews, ¼ cup – 5 grams
Pecans, ¼ cup – 2.5 grams
Sunflower seeds, ¼ cup – 6 grams
Pumpkin seeds, ¼ cup – 8 grams
Flax seeds – ¼ cup – 8 grams
Dry Measure Equivalents
3 teaspoons 1 tablespoon 1/2 ounce 14.3 grams
2 tablespoons 1/8 cup 1 ounce 28.3 grams
4 tablespoons 1/4 cup 2 ounces 56.7 grams
5 1/3 tablespoons 1/3 cup 2.6 ounces 75.6 grams
8 tablespoons 1/2 cup 4 ounces 113.4 grams
12 tablespoons 3/4 cup 6 ounces .375 pound
32 tablespoons 2 cups 16 ounces 1 pound
Wafting poison makes fertile ground for suit in Stearns County
Oluf Johnson’s 1,500-acre farm in Stearns County is an organic island in a sea of chemically treated corn and soybeans.—Improperly applied pesticides repeatedly drift over from neighboring farms, often with dire consequences for Johnson. But now, thanks to a new court ruling, he and other farmers can sue to recover their losses.—Letting damaging chemicals cross property lines is trespassing, the Minnesota Court of Appeals ruled on Monday. Moreover, since those pesticides made his crop unsalable in the organic market, Johnson is entitled to damages from the company that applied it, the Paynesville Farmers Union Cooperative Oil Co., the court said.—“Whenever this happens it will give people with overspray a legal avenue to pursue,” said Doug Spanier, an attorney with the Minnesota Department of Agriculture, which administers pesticide enforcement regulations in the state. And that could go for any farmer whose crop is made inedible by someone else’s chemical spray and even homeowners whose property has been damaged by a neighbor’s overuse of RoundUp, legal experts said.–
It’s one case among many across the country that illustrate how the fight over pesticide use is becoming increasingly contentious. Consumers and health experts are worried about the consequences of pesticides and herbicides in the food chain, and the demand for organically grown food is rising in lockstep.
Courts are responding—Recently, an organic farmer in California won $1 million in damages when pesticides were carried by fog from faraway fields to his own. He had to throw away a season’s worth of herbs destined for organic markets.—The Minnesota court’s decision on Monday “puts it in line with how other jurisdictions have dealt with this,” said Alexandra Klass, a professor of environmental law at the University of Minnesota. “The vast majority of jurisdictions find that pesticide drift is a trespass.”—
The state Agriculture Department said it fields 100 to 150 complaints a year from farmers about overspraying. But only about 35 a year result in some kind of financial penalty, state agriculture officials said.—For Johnson and his wife, Debra, it’s been a long, hard fight. Their attorney, Arlo Vande Vegte of Long Lake, said they would not comment on the decision because talking about it publicly could jeopardize their case. It will get another hearing in Stearns County District Court, where it was originally dismissed, he said.—But their story was detailed by the appeals court.—The Johnsons made the decision to become organic farmers in the 1990s, an arduous process that takes at least three years of careful planning and scrupulous record keeping. They asked the local pesticide cooperative, Paynesville Farmers Union, to take precautions with spraying around the farm.—Nonetheless, the cooperative repeatedly sprayed pesticide and herbicide on neighboring fields in a way that violated Minnesota law, the court said in its decision.—The attorney representing the cooperative did not return phone calls on Monday.
The first time it happened in 1998, the cooperative apologized but refused to pay the Johnsons for the damage caused by the overspraying. When it happened again in 2002, Johnson complained to the Agriculture Department, which determined the chemicals had been sprayed illegally, tainting Johnson’s crop.—He sold it at lower, nonorganic prices, and, following federal rules, removed the contaminated field from production for three years. That time the cooperative settled out of court with the Johnsons.–But it happened again in 2005, 2007 and 2008. In all, the state cited the cooperative four times for violating pesticide laws by applying the chemicals on windy days.—-But the Johnsons also paid a price each time it happened. They had to burn fields and plow under soybeans and take their fields out of production. In 2009 they sued the co-op, charging negligence and trespassing.—-But the district court threw out the suit, saying Minnesota does not recognize trespassing “by particulate matter,” and that the Johnsons could not prove damages. The Appeals Court disagreed. It said that thrown objects and even bullets constitute trespass, and that the state Supreme Court has ruled that beekeepers can collect damages for pesticide-contaminated bees that destroyed their hives.—Perhaps even more significant for other organic farmers, the Johnsons’ attorney said, they are entitled to damages because they couldn’t sell their tainted crops in the organic market.
Recipe For a Peanut Butter Delight—– You will need honey–Nut of Choice–Rosemary extract or dried ( if dried use one tablespoon) –Black seed extract or dried ( if dried use 1 tablespoon) and Tangerine essential oils 20 drops -Creatine 20 grams Cinnamon Powder 1 tablespoon and Cardamon powder 1 tablespoon–take 6 oz of honey and allow to blend for about 5 minutes til almost liquefying oor really soft flowing—then take 20 grams of Creatine—add 1 oz of Black Seed Extract—add ! oz of rosemary extract -Add 20 drops of tangerine essential oils—allow to fuse then add Cinnamon Powder 2 oz and add Cardamon 3 tablespoons and as it is fusing start adding peanuts in small increments you will eventually need a cup ( more or less depending on how thick you like it—allow to blend till everything looks completely fused—then when done pour into a glass container— consume as you like –straight up out of the jar or add to smoothie or a ice cream delight ( non soy and no artificial flavoured or canola—the protein is high and the other nutritional values are as well to protect the system and enhance the strength and endurance and immunitiy