Scrips 2012

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    Scripts 2012

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    Calcium may enhance probiotic survival in the gut, cut cholesterol levels

    Combining calcium phosphate supplements with probiotic Lactobacillus paracasei may enhance the colonization of the probiotic in the gut, and boost reductions in LDL cholesterol levels, says a new study with humans. — Calcium in the form of pentacalcium hydroxy-triphosphate, combined with Lactobacillus paracasei (LPC37) was associated with significant reductions in total and LD cholesterol following four weeks of supplementation, and the results were greater than those observed for L. paracasei alone, according to findings published in Clinical Nutrition. –“To the best of our knowledge, there are no published studies examining the influence of a combinatory supplement consisting of probiotics and calcium phosphate on the faecal microbiota and on cholesterol metabolism in humans,” wrote researchers from Friedrich Schiller University Jena in Germany. –“The results of the present human study imply that calcium phosphate positively affects the colonization of LPC37 in the human gut under conditions of combinatory supplementation of calcium phosphateand LPC37.

    “This combined supplementation is also capable of beneficially modulating blood lipids in healthy, hypercholesterolemic men and women.” –Probiotic potential – The study adds to the ever growing body of science supporting the potential benefits of probiotics. — On Tuesday, an elegant study by Dr Jeff Gordon and his team at the Washington University School of Medicine in St. Louis revealed that probiotic bacteria consumed in a yogurt may not change the host’s gut populations, but they do influence carbohydrate metabolism by the resident microbes. — The new study suggests that calcium phosphate may enhance the activities of L. paracasei. –Study details — Led by Gerhard Jahreis, the Jena, Germany-based researchers recruited 34 omnivorous men and women with moderately elevated blood cholesterol levels to participate in their double-blind, placebo-controlled, cross-over study. — Participants were divided into two groups: One was provided with a probiotic drink containing 10 billion colony forming units (CFUs) per day of L. paracasei (Danisco) for four weeks, while the second group received the probiotic plus an additional gram of pentacalcium hydroxy-triphosphate. — After the intervention period, all participants had a two week period without intervention – the so-called wash out period – followed by two weeks of receiving placebo. After this they were crossed over to the other intervention for another four weeks. — Results showed that the combined intervention was associated with a significant reduction in total and LDL cholesterol levels, compared with the probiotic alone and placebo. —“There are two possible explanations for this observation,” said the researchers, “either LPC37 and calcium phosphate act synergistically, or the cholesterol-lowering effect of LPC37 + calcium phosphate is due to the action of calcium phosphate in the human gut.” — With reference to other studies that have shown an effect of calcium supplementations on blood lipids to a similar extent as measured in the current study, the researchers proposed that the “cholesterol-lowering effect is solely due to the calcium phosphate supplement”. — In addition, the level of L. paracasei and all lactobacilli in the feces increase significantly following both the combined and probiotic only interventions, compared with placebo.

    “There was a significantly positive correlation between the fecal concentration of calcium and the concentration of L. paracasei,” wrote the researchers.

    “This supports the hypothesis that calcium phosphate positively influences the colonization of L. paracasei in the human gut.” Source: Clinical Nutrition Published online ahead of print, doi: 10.1016/j.clnu.2011.09.013 “A combination of calcium phosphate and probiotics beneficially influences intestinal lactobacilli and cholesterol metabolism in humans” Authors: U. Trautvetter, B. Ditscheid, M. Kiehntopf, G. Jahreis

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    Probiotics may influence carbohydrate metabolism

    Probiotic bacteria consumed in a yogurt may not change the host’s gut populations, but they do influence carbohydrate metabolism by the resident microbes, according to an ‘elegant’ new study using identical twins and germ-free mice. — Probiotics in a yogurt were not found to colonize the gut microflora when studied in identical twins, but additional study in mice revealed that ingestion of the probiotic bacteria produced a change in many metabolic pathways, particularly those related to carbohydrate metabolism. — Researchers led by Dr Jeffrey Gordon at the Washington University School of Medicine, St. Louis, published their results yesterday in Science Translational Medicine. — In an accompanying perspective article the study was described as “elegant” by Jordan Bisanz and Gregor Reid from the Lawson Health Research Institute at the University of Western Ontario.

    Dr Gordon and his team have made a habit of advancing our understanding of gut microbe populations and their interactions with their hosts. In 2006, the St Louis-based researchers reported in Nature (Vol. 444, pp. 1022-1023, 1027-1031) that microbial populations in the gut are different between obese and lean people, and that when the obese people lost weight their microflora reverted back to that observed in a lean person, suggesting that obesity may have a microbial component. –Roadmap

    “One of the questions that this field is asking is what are the effects of these organisms on individuals,” said Dr Gordon in an audio podcast with Science Translational Medicine . —“Can we create a discovery pipeline where we can analyze their effects under highly controlled conditions – more controlled than we can achieve with human studies – and having interrogated those models, can we translate the information to humans to guide clinical trials, and gain a greater degree of insight about their effects?” — And that is what the researchers appear to have created. According to Bisanz and Reid, “a valuable roadmap has now been produced to guide future research on how exogenous organisms affect the host – and specifically its microbiome”. — In an email to NutraIngredients-USA, Prof Reid added: “The study is important as it tests a probiotic food in humans then investigates the mechanisms of action using a variety of state-of-the-art methods. The researchers then create a reduced microbiota in an animal and show that the effects of the probiotic can to some extent be mimicked.” —Study details — Dr Gordon and his team examined the potential of four months of consuming a commercial yogurt containing Bifidobacterium animalis subsp. lactis, two strains of Lactobacillus delbrueckii subsp. bulgaricus, Streptococcus thermophilis, and Lactococcus lactis subsp. cremoris, in seven pairs of female twins in their 20s and 30s. Dr Gordon has not named the product to avoid being seen as endorsing it. — The researchers also tested the effects of the yogurt in gnotobiotic mice, or mice that were completely germ-free except for the 15 specially introduced strains of bacteria that are present in the human gut. — Results showed that, in both mice and humans, the probiotic yogurt did not modify the composition of the gut microbial communities. — However, further analysis of using genome sequencing, and transcriptomic and metabolomic analyses, revealed a change in marked changes in numerous metabolic pathways, particularly those related to the processing of carbohydrates. — According to Bisanz and Reid, “a real strength of [Dr Gordon’s] study is that ingestion of a fermented milk product, essentially a commercial probiotic yogurt, was monitored by having the microbial transcriptional responses from the animal model acting as biomarkers for interrogation of the metatranscriptome data sets of the human twins. —“The apparent stability of the twins’ gut microbiota, despite a twice daily intake of the fermented milk product containing bifidobacteria and lactic acid-producing bacteria, demonstrates the remarkable ability of the host’s microbes to withstand the arrival of new strains of bacteria.”

    What next? — Dr Gordon and his co-workers note that his team’s experimental model could be used to identify biomarkers and other ‘mediators of the effects of existing or new probiotic strains’ The model may also help scientists identify potential new prebiotics that could also modify the metabolic effects of probiotic species. — Bisanz and Reid added that the “incredible precision and thoroughness of [Dr Gordon’s] study will not be easy to duplicate, but they have certainly laid a valuable pathway for others to follow.” Source: Science Translational Medicine 26 October 2011, Volume 3, Issue 106, 106ra106 “The Impact of a Consortium of Fermented Milk Strains on the Gut Microbiome of Gnotobiotic Mice and Monozygotic Twins” Authors: N.P. McNulty, T. Yatsunenko; A. Hsiao, et al.

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    Pineapple bromelain has anti-tumor properties superior to the chemo-agent 5-fluorouracil. – In vivo antitumoral activity of stem pineapple (Ananas comosus) bromelain.

    Abstract Source: Planta Med. 2007 Oct;73(13):1377-83. Epub 2007 Sep 24. PMID: 17893836

    Abstract Author(s): Roxana Báez, Miriam T Lopes, Carlos E Salas, Martha Hernández

    Abstract—–Stem bromelain (EC 3.4.22.32) is a major cysteine proteinase,[U1] isolated from pineapple ( Ananas comosus) stem. Its main medicinal use is recognized as digestive, in vaccine formulation, antitumoral and skin debrider for the treatment of burns. To verify the identity of the principle in stem fractions responsible for the antitumoral effect, we isolated bromelain to probe its pharmacological effects. The isolated bromelain was obtained from stems of adult pineapple plants by buffered aqueous extraction [U2]and cationic chromatography. The homogeneity of bromelain was confirmed by reverse phase HPLC, SDS-PAGE and N-terminal sequencing. The in vivo antitumoral/antileukemic activity was evaluated using the following panel of tumor lines: P-388 leukemia, sarcoma (S-37), Ehrlich ascitic tumor (EAT), Lewis lung carcinoma (LLC), MB-F10 melanoma and ADC-755 mammary adenocarcinoma. Intraperitoneal administration [U3]of bromelain (1, 12.5, 25 mg/kg), began 24 h after tumor cell inoculation in experiments in which 5-fluorouracil (5-FU, 20 mg/kg) was used as positive control. The antitumoral activity was assessed by the survival increase (% survival index) following various treatments. With the exception of MB-F10 melanoma, all other tumor-bearing animals had a significantly increased survival index after bromelain treatment. The largest increase ( approximately 318 %) was attained in mice bearing EAT ascites and receiving 12.5 mg/kg of bromelain. This antitumoral effect was superior to that of 5-FU, whose survival index was approximately 263 %, relative to the untreated control. Bromelain significantly reduced the number of lung metastasis induced by LLC transplantation, as observed with 5-FU. The antitumoral activity of bromelain against S-37 and EAT, which are tumor models sensitive to immune system mediators, and the unchanged tumor progression in the metastatic model suggests that the antimetastatic action results from a mechanism independent of the primary antitumoral effect.

    Pubmed Data : Planta Med. 2007 Oct;73(13):1377-83. Epub 2007 Sep 24. PMID: 17893836 Article Published Date : Oct 01, 2007

    Study Type : Animal Study

    Diseases : Cancer Metastasis : CK(230) : AC(120), Lung Cancer : CK(423) : AC(182)

    Pharmacological Actions : Anti-metastatic : CK(152) : AC(95)

    Additional Keywords : Drug: 5-flourouracil : CK(68) : AC(23), Food as Medicine : CK(15) : AC(6), Hall of Fame : CK(26) : AC(6), Superiority of Natural Substances versus Drugs : CK(776) : AC(172)

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    Plant Extraction

    The plant materials were cleaned of residual soil and air-dried at room temperature. Plants were ground to a fine powder using a laboratory mill and passed through a 24 mesh sieve to generate a homogeneous powder, stored at room temperature (22–23 °C), and protected from light until extraction.

    Methanolic extractions were conducted using 250 mg sample of each ground plant material, of the used parts (see Table (1), in 10 mL methanol (80%), at 37 °C for 3 h, in a shaking water bath. After cooling, the extract was centrifuged at 1500 g for 10 min, and the supernatant was recovered. The solvent was evaporated under vacuum at 40°C using a rotary evaporator. The solid residues were collected and stored in dry condition until analysis

    ( this is away to concentrate your remedy by allowing the materials to be in a solvent sealed and placed in 100degree water so that the materials will extract and become even more concentrated and then poured into a evaporator to remove all the alcohol and residue to all you have is a extract )

    Preparation of Extract for In Vitro Assay

    The tested extracts were initially dissolved in DMSO to give five different stock solutions with a concentration range of 0.625-10.0 mg/mL (0.625, 1.25, 2.5, 5.0 and 10mg/mL). Subsequently, 20 μL aliquot of each stock solution was used in the reaction mixture to give a final concentration range of 12.5- 200 μg/mL (12.5, 25, 25, 50 and 200 μg/mL).

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    Serrapeptase’s Uses

    Serrapeptase is known in several other names such as serralysin, serratiapeptase, serratia peptidase, serratio peptidase, or serrapeptidase and is derived from the microorganism called Serratiopeptidase which is found present in the intestines of silkworm which allows the emerging moth to dissolve its cocoon. Serrapeptase is produced by purification from culture of Serratia E-15 bacteria.

    It is an enzyme that eats or digests non-living tissue, blood clots, cysts, arterial plaque, inflammation, internal scar tissue as well as help with new external scars by either converting it into amino acids or excreted in the normal manner. Here are a few uses for Serrapeptase:

    As a natural solution to pain & inflammation–With Serrapeptase, chronic inflammation can be resolved or minimized in a natural and balanced way. Symptoms of inflammation disappear within 1 to 2 weeks but health practitioners normally recommend administration for up to 4 weeks to reassess the condition. –As a natural alternative to NSAIDs–Since the discovery of Serrapeptase and its wonderful healing properties with inflammation, it has become the favored choice compared to salicylates, ibuprofen and the more potent NSAIDs. Because Serrapeptase is naturally occurring, there fore no inhibitory effects on prostaglandins have been recorded and is devoid of gastrointestinal side effects.

    As an alternative to Warfarin—Warfarin is known for its blood thining properties that is why the proper dosage each time is sued and monitored. Serrapeptase also has blood thinning properties though not as potent as Warfarin. Many natural remedies and dietary improvements will thin the blood naturally that is why a doctor’s recommendation is always needed. Though that, blood thinning at certain levels is good as it makes the blood healthy if the blood is already too thick and the platelets are sticking together. Serrapeptase does not thin blood in an unhealthy way, rather it promotes healthy production of blood cells to stop chronic inflammation.

    As treatment for arterial blockage—Dr. Hans Neiper’s findings for serrepeptase is probably the main reason why serrapeptase is popular. Dr. Hans found that Serrapeptase has properties of treating arterial blockage in his coronary patients. It works by dissolving blood clots and shrinking varicose veins. Several of Dr. Hans’ patients who were scheduled for amputation recovered quickly through treatments of Serrapeptase. Serrapeptase is always known as a natural anti-inflammatory and as a strong protease that can dissolves the dead proteins that bind the plaque blocking the arteries. —As a natural inflammation treatment for: Arthritis, Ankylosing Spondylitis, Osteoporosis, Lupus, Diabetes, MS, Headaches and Migraines caused by inflammation –Lungs – Emphysema, Bronchitis, Pulmonary Tuberculosis, Bronchial Asthma, Cystic Fibrosis, Bronchiectasis etc ,Inflammatory bowel diseases such as Crohn’s, Colitis etc, Inflammation in joints or muscles e.g. Fibromyalgia, Repetitive strain injuries, Breast Engorgement, Fibrocystic Breast Disease, Cysts, Cardiovascular Disease, Arterial Disease, Angina, Blood clots, Varicose Veins, Eye, nose and throat problems from inflammation or blocked veins – ear infections, hayfever, swollen glands, laryngitis, rhinitis, sinusitis, runny nose,Sports Injuries, traumatic swelling, post operative swellings, leg ulcers Post operative healing -Enlarged Prostate

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    Serrapeptase Effects and Heals – can safely remove inflammation and dead tissue that causes pain, blocked arteries, varicose veins, lung problems and other common symptoms.–Serrapeptase, serrazyme, Serraplus+, serraplus+, inflammation, blocked arteries, varicose veins, dead tissue, lung problems, scar tissue, scars, Pain, Ankylosing Spondylitis, Arthritis, back problems, Diabetes, Leg Ulcers, Osteoporosis, Polymyalgia Rheumatica, Prostate Problems, Repetitive Strain (RSI) Carpal Tunnel, Rheumatoid Arthritis, Breast Engorgement, Cystitis, joints or muscles, Fibromyaligia, Fibrocystic Breast Disease, Headaches, Migranes, Inflammatory bowel diseases, Ulcerative Colitis, Crohn’s, IBS, Lupus, Lung, Chest, Asbestosis, Miners and Farmers Lung, Bronchietasis, Bronchial Asthma, Bronchitis, Coughs, Cystic Fibrosis, Emphysema, Pulmonary Tuberculosis, Eye Problems, Blocked veins, Multiple Sclerosis, MS, Neurological problems, Damaged Nerves, Ear, Nose, Throat problems, Chronic ear infections, Catarrhal Rhinopharyngitis, Hayfever, Sore Throat, Swollen Glands, Laryngitis, Runny nose, Rhinitis, Sinusitis problems, Trauma, Sports Injuries prevention.

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    Serrapeptase Reference

    l.. Kee WH. Tan SL, Lee V. Salmon YM. The treatment of breast engorgement with Serrapeptase (Danzen): a random ized double-blind controlled trial. Singapore Med J. 1989:30(1):48-54.

    2. M izukoshi, D. et al. A double-blind clinical study of serrapeptase in the treatment of chronic sinusitis. Igaku Ayrni 109:50-62.1979.

    3. Carratu, L. et al. Physio-chemical and rheological research on mucolytic activity of serrapeptase in chronic broncho-pneumopathies. Curr. Ther. Res. 28(6):937-951. 1980.

    4. Braga, P.C. et al. Effects of serrapeptase on muco-ciliary clearance in patients with chronic bronchitis. Curr. Ther. Res. 29(5):738-744,1981.

    5. Mazzonie, A. et al. Evaluation of serrapeptase in acute or chronic inflammation of otorhinolaryngology pathology: a multicentre, double-blind randomized trial versus placebo. J. int. Med. Res. 18(5):379-388,1990.

    6. Kakinumu, A. et al. Regression of fibrinolysis in scalded rats by administration of serrapeptase. Biochem. Pharmacol. 31:2861-2866,1982.

    7. Marly, M. Enzymotherapie anti-inflammatoire a l’aide de la serrapeptase: resultats cliniques en traumatologie et en ORL. C RTherapeut. 3:9-19,1985.

    8. Odagiri, J. et al. Clinical applications of serrapeptase in sinusitis. Med. Consult. New Remedy 6:201-209, 1979.

    9. Yamazaki, J. et al. Anti-inflammatory activity of TSP, a protease produced by a strain of Serratia. Folia Pharmacol. Japon. 6^302-314,1967.

    I0. Harad~, Y. Clinical efficacy of serrapeptase on buccal swelling after radical operation for chronic sinusitis. Igaku Ayumi 123:768-778.1982.

    1 I. Matsudo, A. et at. Effect of serrapeptase (Danzen) on inflammatory edema following operation for thyroid disease. Med. Consult. New Remedy 18:171-175, 1981.

    12. Fujitani, T. et al. Effect of anti-inflammatory agent on transfer of antibiotics to the maxillary sinus mucosa in chronic sinusitis. Otorhinolaryngol. Clin. North Am. 66:557-565. 1976.

    13. Tago. T. and Mitsui, S. Effects of serrapeptase in dissolution of sputum, especially in patients with bronchial asthma. Jap. Clin. Exp. Med. 49:222-228, 1972.

    14. Mazzonie, A. et al. Evaluation of serrapeptase in acute or chronic inflammation of otorhinolaryngology pathology: a multicentre, double-blind randomized trial versus placebo. J. int. Med. Res. 18(5):379-388,1990.

    15. Kase, Y. et al. A new method for evaluating mucolytic expectorant activity and its application. II. Application to two proteolytic enzymes, serrapeptase and seaprose. Arzneimittelforschung 32:374-378,1982.

    16. Marriott, C. Modification of the rheoloaical properties of mucus by drugs. Adv. Exp. Med. Biol. 144^75-84, 1982.

    17. Majima. Y. et al. Effects of orally administered drugs on dynamic viscoelasticity of human nasal mucus. Am. Rev. Respit. Dis. 141:79-83.1990.

    18. Miyata, K. Intestinal absorption of serrapeptase. J ApplBiochem. 1980:2:111-16.

    19. Aso T. et al. Breast engorgement and its treatment: Clinical effects of Danzen (serrapeptase) an anti-inflammatory enzyme preparation. The world of Obstetrics and Gynecology (Japanese). 1981:33:371-9.

    20. Esch PM, Gemgross H. Fabian A. Reduction of postoperative swelling. Objective measurement of swelling of the upper ankle joint in treatment with serrapeptase-a prospective study (German). FortschrMed. 1989; 107(4):67-8, 71-2.

    21. Majima Y, lnagaki M, Hirata K. Takeuchi K, M orishita A, Sakakura Y. The effect of an orally administered proteolytic enzyme on the elasticity and viscosity of nasal mucus. Arch Otorhinolaryngol. 1988;244(6):355-9.

    22. Selan L, Berlutti F, Passariello C. Comodi-Ballanti MR, Thaller MC. ?roteolytic enzymes: a new treatment strategy for prosthetic infections? Antimicrob Agents Cheroother. 1993; 37(12):2618-21.

    23. Koyama A, Mori J, Tokuda H, Waku M, Anno H, Katayama T, Murakami K, Komatsu H, Hirata M, Arai T, et al. Augmentation by serrapeptase of tissue permeation by cefotiam (Japanese). Jpn JAntibiot. 1986; 39(3):761-7

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    [U1]Cysteine Protein or amino
    [U2]The boiled them down

    [U3]The membrane that lines the walls of the abdomen and the pelvis (called the parietal peritoneum) and encloses the abdominal and pelvic organs (called the visceral peritoneum.)
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    Show Of The Week January 6 2012

    Artificial sweetener consumption is associated with urinary tract tumors.– Aceslfame K

    Effect of a Herbal-Leucine mix on the IL-1β-induced cartilage degradation and inflammatory gene expression in human chondrocytes.

    Anti-tumorigenic activity of five culinary and medicinal herbs grown under greenhouse conditions and their combination effects

    DHA used in infant formula products comes from genetically modified algae

    Antioxidant capacity of hesperidin from citrus peel using electron spin resonance and cytotoxic activity against human carcinoma cell lines.

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    Artificial sweetener consumption is associated with urinary tract tumors. – Aceslfame K

    Artificial sweetener consumption and urinary tract tumors in Cordoba, Argentina.

    Prev Med. 2008 Jul;47(1):136-9. Epub 2008 Apr 8. PMID: 18495230

    Abstract Author(s): M M Andreatta, S E Muñoz, M J Lantieri, A R Eynard, A Navarro Article Affiliation:

    Escuela de Nutrición, Facultad de Ciencias Médicas, Universidad Nacional de Córdoba, Argentina. Abstract:

    OBJECTIVE: To determine the role of the habitual use of the most common artificial sweeteners (AS) in the development of urinary tract tumors (UTT) in Argentina. METHODS: Case-control study of 197 patients with histologically confirmed UTT of transitional varieties, and 397 controls with acute, non-neoplastic, and non-urinary tract diseases, admitted to the same hospitals in Córdoba (Argentina) between 1999 and 2006. All subjects were interviewed about their use of AS and their exposure to other known or suspected risk factors for UTT. RESULTS: Fifty-one UTT patients (26%) and 87 controls (22%) used AS. The risk of UTT was significantly increased in long-term (>or =10 years) AS users compared with none-AS users. The OR (95% CI) for long-term consumers was 2.18 (1.22-3.89) and for short-term users was 1.10 (0.61-2.00) after adjustment for age, gender, BMI, social status. and years of tobacco use. CONCLUSION: Regular use of AS for 10 years or more was positively associated with UTT.–Study Type : Human Study

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    Effect of a Herbal-Leucine mix on the IL-1β-induced cartilage degradation and inflammatory gene expression in human chondrocytes.

    BMC Complement Altern Med. 2011;11:66-Authors: Akhtar N, Miller MJ, Haqqi TM

    Abstract
    BACKGROUND: Conventional treatments for the articular diseases are often effective for symptom relief, but can also cause significant side effects and do not slow the progression of the disease. Several natural substances have been shown to be effective at relieving the symptoms of osteoarthritis (OA), and preliminary evidence suggests that some of these compounds may exert a favorable influence on the course of the disease. The objective of this study was to investigate the anti-inflammatory/chondroprotective potential of a Herbal and amino acid mixture containing extract of the Uncaria tomentosa, ( cats claw) Boswellia spp ( myrrh or frankinsense )., Lepidium meyenii( maca ) and L-Leucine on the IL-1β-induced production of nitric oxide (NO), glycosaminoglycan (GAG), matrix metalloproteinases (MMPs), aggrecan (ACAN) and type II collagen (COL2A1) in human OA chondrocytes and OA cartilage explants.—METHODS: Primary OA chondrocytes or OA cartilage explants were pretreated with Herbal-Leucine mixture (HLM, 1-10 μg/ml) and then stimulated with IL-1β (5 ng/ml). Effect of HLM on IL-1β-induced gene expression of iNOS, MMP-9, MMP-13, ACAN and COL2A1 was verified by real time-PCR. Estimation of NO and GAG release in culture supernatant was done using commercially available kits. –RESULTS: HLM tested in these in vitro studies was found to be an effective anti-inflammatory agent, as evidenced by strong inhibition of iNOS, MMP-9 and MMP-13 expression and NO production in IL-1β-stimulated OA chondrocytes (p < 0.05). Supporting these gene expression results, IL-1β-induced cartilage matrix breakdown, as evidenced by GAG release from cartilage explants, was also significantly blocked (p < 0.05). Moreover, in the presence of herbal-Leucine mixture (HLM) up-regulation of ACAN and COL2A1 expression in IL-1β-stimulated OA chondrocytes was also noted (p < 0.05). The inhibitory effects of HLM were mediated by inhibiting the activation of nuclear factor (NF)-kB in human OA chondrocytes in presence of IL-1β.
    CONCLUSION: Our data suggests that HLM could be chondroprotective and anti-inflammatory agent in arthritis, switching chondrocyte gene expression from catabolic direction towards anabolic and regenerative, and consequently this approach may be potentially useful as a new adjunct therapeutic/preventive agent for OA or injury recovery.—PMID: 21854562 [PubMed – indexed for MEDLINE]–You can do this several ways—anytime you increase nitric oxide reduce inflammation ( sodium phosphate) cayenne and tumeric and pineapple –you may see this sort of thing reverse—especially when adding gelatin and comfrey to your daily regimen—or utilizing anti catabolic ( stops the break down of muscle and tissue) substances or materials or foods.

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    Anti-tumorigenic activity of five culinary and medicinal herbs grown under greenhouse conditions and their combination effects.

    J Sci Food Agric. 2011 Aug 15;91(10):1849-54

    Authors: Yi W, Wetzstein HY

    Abstract
    BACKGROUND: Herbs and spices have been used as food preservatives, flavorings, and in traditional medicines for thousands of years. More and more scientific evidence supports the medicinal properties of culinary herbs. Colon cancer is the third leading cause of cancer death in the USA, and the fourth most common form of cancer worldwide. The objectives of this study were to evaluate the antitumor activity of five selected herbs grown under greenhouse conditions, and to study the potential synergistic effects among different herbal extract combinations.
    RESULTS: Thyme, rosemary, sage, spearmint, and peppermint extracts significantly inhibited SW-480 colon cancer cell growth, with sage extracts exhibiting the highest bioactivity, with 50% inhibition at 35.9 µg mL⁻¹, which was equivalent to 93.9 µg dried leaves mL⁻¹ of culture medium. Some mixtures of different herbal extracts had combination effects on cancer cell growth. The inhibitory effects of peppermint + sage combinations at a 1:1 ratio were significantly higher than rosemary + sage combinations at 1:1 ratio, although peppermint extracts showed lower inhibition than rosemary extracts.–CONCLUSION: Extracts from herb species (thyme, rosemary, sage, spearmint and peppermint) can significantly inhibit the growth of human colon cancer cells. Mixtures of herb extracts can have combination effects on cancer cell growth. The study suggests that these five herbs may have potential health benefits to suppress colon cancer.PMID: 21452174 [PubMed – indexed for MEDLINE]

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    DHA used in infant formula products comes from genetically modified algae

    One of the most vulnerable segments of the population — infants — are being affected as chemical giant Martek Biosciences uses cronyism to have its patented GMO products classified as organic. The National Organic Program is trying to correct this, but in the meantime the “organic” infant formula or baby food parents feed their children could contain industrial Frankenfood.

    History of Irresponsibility—-The story of how this state of affairs came about reveals much on how politics and profit can undermine food safety. Here’s a timeline on how the word “organic” is being undermined, creating a health threat for babies who are fed with formula.

    2002: Food manufacturers begin supplementing infant formula and baby food with synthetic forms of docosahexaenoic acid (DHA) and arachidonic acid (ARA). These polyunsaturated omega-3 and omega-6 fatty acids, naturally present in breast milk, are important components of the human brain and eyes. Although the form of DHA/ARA used in infant formulas is structurally incompatible with the form found in human milk, food manufacturers market their products with the claim that their formulas will make babies more intelligent.

    2006: In spite of the fact that its synthetic DHA/ARA is from laboratory-grown fermented algae and fungus through the use of hexane, a petroleum by-product and EPA-identified neurotoxin, Martek applies for organic status for its products. The USDA’s National Organic Program (NOP) tells Martek its synthetic DHA and ARA does not quality as organic. Martek attorney J. Friedman ignores the decision of NOP staff and contacts NOP director Barbara Robinson to have the decision reversed.

    2009: A front page Washington Post article, “Integrity of Federal ‘Organic’ Label Questioned” uncovers the Martek story. The article quotes Martek’s lawyer saying “I called Robinson up, I wrote an e-mail. It was a simple matter.”

    2002-2010: Parents and medical professionals observe reactions in babies fed with products containing Life’s DHA, the product name Martek gives its patented GMO version of naturally occurring fatty acids. The range of infant health problems includes difficulties breathing and gastrointestinal disorders. When affected babies are no longer fed the formula, the ailments disappear. Although Freedom of Information Act requests reveal hundreds of FDA adverse event reports, the FDA is slow to react.

    2011: FDA announces it will investigate claims that DHA/ARA infant formulas support brain and eye development. The National Organic Program is now trying to remedy its 2006 decision by asking Martek to formally ask permission of the NOP’s National Organic Standards Board to use its DHA and AHA in organic products.

    Products Containing this GMO

    In the meantime, Life’s DHA is being sold in many so-called organic brands which many consumers trust. Paying higher prices for products labeled as organic does not necessarily mean your family’s food does not include this particular Frankenfood. From Martek’s own website, here is a list of infant formulas containing their product which is both genetically modified and typically manufactured using a known toxin:

    Earth’s Best Organic Soy with DHA & ARA (Hain Celestial Group)

    Enfamil LIPIL (Mead Johnson Nutritionals)

    Enfamil Next Step (Mead Johnson)

    Isomil 2 Advance (Abbott Laboratories)

    Nestle Good Start Supreme with DHA & ARA (Nestle USA)

    Parent’s Choice Organic (Wal-Mart)

    Similac Advance (Abbott Nutrition)

    Ultra Bright Beginnings Lipids (PBM Products, LLC)

    There is also a long list of pre-natal supplements as well as vitamins and dietary supplements for infants, children and adults containing this product. A surprisingly wide range of foods and beverages use this GMO substance including Apple Bran Muffins sold at Starbucks; Farm Pride Omega-3 Eggs; Horizon Organic Milk; Kroger Active Lifestyle Premium Light OJ Beverage; Minute Maid Enhanced Pomegranate Blueberry Juice; Pediasure Children’s Beverage; Pompeian OlivExtra Plus and Silk Soymilk. The list of products containing this GMO is multinational, with products in many countries across the globe. If you want to check whether a supplement, food, or beverage you use contains Life’s DHA, the full list is here: http://www.lifesdha.com/Products-Co&#8230;

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    Antioxidant capacity of hesperidin from citrus peel using electron spin resonance and cytotoxic activity against human carcinoma cell lines.

    Pharm Biol. 2011 Mar;49(3):276-82—Authors: Al-Ashaal HA, El-Sheltawy ST

    Abstract

    CONTEXT: Hesperidin is a flavonoid that has various pharmacological activities including anti-inflammatory, antimicrobial and antiviral activities.

    OBJECTIVE: The aim of the study is the isolation of hesperidin from the peel of Citrus sinensis L. (Rutaceae), and the evaluation of its antioxidant capacity and cytotoxicity against different human carcinoma cell lines.

    MATERIALS AND METHODS: In the present work, hesperidin is identified and confirmed using chromatographic and spectral analysis. To correlate between hesperidin concentration and antioxidant capacity of peel extracts, extraction was carried out using 1% HCl-MeOH, MeOH, alkaline solution, the concentration of hesperidin determined qualitatively and quantitatively using high performance thin layer chromatography (HPTLC), high performance liquid chromatography (HPLC) analysis, in vitro antioxidant capacity of hesperidin and the extracts against free radical diphenylpicrylhydrazyl (DPPH•) performed using an electron spin resonance spectrophotometer (ESR). Cytotoxic assay against larynx, cervix, breast and liver carcinoma cell lines was performed.- RESULTS: Hesperidin was found to be moderately active as an antioxidant agent; its capacity reached 36%. In addition, the results revealed that hesperidin exhibited pronounced anticancer activity against the selected cell lines. IC₅₀ were 1.67, 3.33, 4.17, 4.58 µg/mL, respectively.– DISCUSSION AND CONCLUSION: Orange peels are considered to be a cheap source for hesperidin which may be used in the pharmaceutical industry as a natural chemopreventive agent. Hesperidin and orange peel extract could possess antioxidant properties with a wide range of therapeutic applications.–PMID: 21323480 [PubMed – indexed for MEDLINE]

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    Show Of The Week January 9 2012

     

    Delay Breastfeeding to “Improve” Vaccination?

    Senators Give Supplements a Lifeline

    When Overeating, Calories — Not Protein — Contribute to Increase in Body Fat
    Fountain of Youth in Bile- Longevity Molecule Identified

    Cancer-Killing Compound Spares Healthy Cells- Lithocholic acid

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    Delay Breastfeeding to “Improve” Vaccination?

    Over the course of the past few years, we have been gathering studies from the US National Library of Medicine on the adverse, unintended health effects of vaccination [1], in an attempt to offset the one-sided propaganda foisted upon the public, namely, that all vaccines are unequivocally “safe” and “effective,” a priori. —Along the way, we happened upon a 2010 study [2] published in the Journal of Pediatric Infections & Diseases which has been shared more than any other article on our database, and which suggests that breastfeeding should be delayed in order to prevent immune factors within breast milk from inactivating vaccine-associated antibody titer elevations and “vaccine potency.” The concluded the study with the following statement:–“INTERPRETATION: The lower immunogenicity and efficacy of rotavirus vaccines in poor developing countries could be explained, in part, by higher titers of IgA and neutralizing activity in breast milk consumed by their infants at the time of immunization that could effectively reduce the potency of the vaccine. Strategies to overcome this negative effect, such as delaying breast-feeding at the time of immunization, should be evaluated.”—It is not difficult to comprehend what caused the flurry of interest in this study. Readers were a the obviously disturbed by the suggestion that women in the underdeveloped world temporarily stop breast feeding (often the only source of infant nutrition) in order to increase the vaccine’s purported “efficacy.” Are we to assume that these breast milk deprived infants should consume formula* in the interim? And to what end? So that the vaccine can generate a temporary spike in antibody production, which is no measure of real-world effectiveness? —*Note: Infant formula has been linked to 48 adverse effects [3], including increased mortality.—First, it should be made clear that the term “efficacy,” when used in the context of a vaccine’s antibody-elevating effects, does not equate to effectiveness, i.e. whether or not a vaccine actually works in real life to protect against the infectious agent of concern.–It is this semantic trick (conflating and confusing “efficacy” with “effectiveness”) which convinces most of the “developed” world that vaccine research is “evidence-based” and focused on creating enhanced immunity, when in fact it is primarily a highly successful business enterprise dependent on defrauding its “customers” of both their money and health. The dangers of common vaccines [1] are so well known by “health experts,” and the manufacturers who produce, them that their risk (like nuclear power) is underwritten by world governments. The importance of this fact can not be overestimated or understated.———–Introducing foreign pathogenic DNA, chemicals, metals, preservatives, etc., into the body through a syringe will generate a response not unlike kicking a bee hive. The harder you kick that beehive, the greater will be the “efficacy” (i.e. elevated antibodies), but the actual affinity that these antibodies will have for the antigen (i.e. pathogen) of concern, can not be guaranteed; nor must the vaccine reseachers prove antibody-antigen affinity to receive FDA approval. –Also, valuable immune resources are wasted by generating “false flag” responses to threats which may not readily exist in the environment, e.g. there are over 200 forms of influenza A, B & C which can cause the symptoms associated with annual influenza A, so the seasonal trivalent flu vaccine only takes care of little more than 1% of the possible vectors of infection – and often at the price of distracting resources away from real threats and exhausting and/or damaging the entire immune apparatus. Truth be told, there is actually a shocking lack of evidence to support flu vaccines [4], in any age or population.—What’s worse, the vaccine response can “blow back” causing loss of self-tolerance and, via the resultant Th2 dominant immune system, the body can attack itself (auto-immunity). In the meantime, the first line of defense against infection (Th1) is compromised and this “front door” can be left wide open to unmet infectious challenges.—It is clear that one can create a synthetic immune response through vaccination, but it is not likely to result in enhanced immunity, insofar as real-world effectiveness is concerned, which is the only true judge of whether a vaccine is valuable or not. One might view the basic criteria used by vaccine researchers, namely, that generating elevated antibody titers proves the value of the vaccine, oppositely: proving the vaccine is causing harm to the developing infant by generating unnecessarily elevated antibodies by any means necessary, i.e. throwing the chemical and biological kitchen sink at the immune system, e.g. aluminum, phenol, diploid (aborted fetal) cells, peanut oil, pertactin, etc. –In the same way that secretory IgA from breast milk [5] deactivates a broad range of “natural” antigenic challenges for the infant, this breast milk derived, indispensable immune factor also deactivates the inherently disruptive and immunotoxic antibody-generating vaccine antigens and adjuvants. Rather than view this as the “enemy,” the reduction in antibodies that accompanies a well-nourished breastfed infant’s blood work, after the highly invasive and unnatural introduction of a vaccine, is a sign of health, not disease.—-This study struck a deep psychic chord out there. Images of phallic syringes stabbing away jealously at the symbolic breast of Nature come to mind, as the increasingly invasive ethos of modern medicine — always attempting to “improve on Nature” — drives us sick, mentally and physically. Can’t we just leave the timeless wisdom of mothering and nourishing that is woven into the mother-infant dyad alone?

    Additional Topics:

    Infant Formula: Risk Factor for 48 Diseases [3]

    Breast Feeding: Risk Reduction for 59 Diseases [6]

    Vaccination Research Database [1]

    Article: Infant Formula For Disaster [7]

    Vaccine researchers have suggested delaying breastfeeding to “improve” vaccine efficacy. Images of phallic syringes stabbing away jealously at the symbolic breast of Nature come to mind, as the increasingly invasive ethos of modern medicine — always attempting to “improve on Nature” — drives us sick, mentally and physically. Can’t we just leave the timeless wisdom of mothering and nourishing that is woven into the mother-infant dyad alone?

    Source URL: http://www.greenmedinfo.com/blog/researchers-delay-breastfeeding-improve-vaccination

    Links:
    [1] http://www.greenmedinfo.com/page/vaccine-research
    [2] http://www.greenmedinfo.com/article/vaccination-proponents-have-suggested-breastfeeding-should-be-delayed-order-prevent-immune-f
    [3] http://www.greenmedinfo.com/toxic-ingredient/infant-formula
    [4] http://www.greenmedinfo.com/blog/shocking-lack-evidence-supporting-flu-vaccines
    [5] http://www.greenmedinfo.com/substance/breast-milk
    [6] http://www.greenmedinfo.com/therapeutic-action/breastfeeding
    [7] http://www.sayerji.com/published-writings/infant-formula-for-disaster

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    Senators Give Supplements a Lifeline

    Will it be enough to rein in FDA’s outrageous power grab?

    ANH-USA, together with a number of supplement trade organizations, went to Capitol Hill to plead our case about the FDA’s profoundly flawed NDI (new supplement) draft guidance in the offices of two powerful senators and longtime friends of natural health, Sen. Tom Harkin (D-IA) and Sen. Orrin Hatch (R-UT). Our visit was preceded by all the letters you have been sending to Congress, which have immeasurably increased the visibility of this issue. As you know, if this draft guidance stands, it would allow FDA to arbitrarily deny the sale of any supplement created (or modified) in the past seventeen years [1]. Immediately after this meeting, Sens. Harkin and Hatch wrote to FDA Commissioner Margaret Hamburg and formally asked the FDA to withdraw its guidance document.——-The senators urged FDA to begin work on a new draft that provides needed clarification on what constitutes a New Dietary Ingredient (NDI)—but, in their words, does not undermine Congress’s desire to provide consumers with access to safe, affordable dietary supplement products. Exactly!——–These senators were uniquely qualified to make such a request, since they were the principal authors of DSHEA, the Dietary Supplement Health and Education Act of 1994. “When Congress included language in the Food Safety Modernization Act (FSMA) directing FDA to clarify when a dietary supplement ingredient is a new dietary ingredient, the expectation was that the guidance would be consistent with DSHEA,” they write. “Unfortunately, the draft guidance serves to undermine DSHEA in a number of important respects.”

    They go on to outline the various arguments that we have been making in these pages for some time:

    The requirement for a manufacturer to submit an NDI notification for every dietary supplement containing an NDI is directly contrary to the language of DSHEA, which requires notification only of the intent to use an NDI;
    This new requirement is burdensome and would impose substantial additional costs on manufacturers, would not provide additional safety benefits, and would undermine access to the safe, affordable nutritional supplements that DSHEA was designed to ensure;
    The NDI guidance’s assertion that synthetic copies of ingredients can never be a dietary ingredient is without any statutory basis, and is contrary to longstanding FDA policy; and
    This guidance is contrary to Congressional intent by grandfathering in only ingredients that were marketed before the enactment of DSHEA—such an argument is particularly specious since “the term dietary supplement wasn’t even defined prior to DSHEA”!
    The senators requested that FDA meet with interested parties to work through all of the issues raised in our and others’ comments. Fortunately, FDA can’t just ignore the senators’ request, because the agency is required to work within legislative intent. Otherwise they would be creating new law—which legally they cannot do. This is one of the arguments we have been making all along—that FDA is in fact making new law with this draft guidance, and now Congress is calling them on it!—-We would like to thank Senators Harkin and Hatch for being such stalwart champions of natural health, and for their leadership in this battle to prevent the FDA from usurping powers that they are not legally entitled to. We also want to thank every one of you for contacting Congress and the FDA and being such a vital part of this process.—We aren’t out of the woods yet—we’ll have another update soon with additional action items for you. The time may come for more specific legislative action, and we may find ourselves battling FDA in the courts as well. That’s why your continued support and activism is so terribly important. Together we can win this one, preserve your access to supplements, and keep supplements from costing as much as drugs.

     

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    Article printed from Welcome to the Alliance for Natural Health – USA: http://www.anh-usa.org

    URL to article: http://www.anh-usa.org/senators-give-supplements-a-lifeline/

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    When Overeating, Calories — Not Protein — Contribute to Increase in Body Fat
    ScienceDaily (Jan. 3, 2012) — In a study conducted among 25 healthy individuals living in a controlled setting who were randomized to overconsumption of different levels of protein diets, those consuming the low-protein diet had less weight gain compared to those consuming normal and high protein diets, and calories alone, and not protein appeared to contribute to an increase in body fat, according to a study in the January 4 issue of JAMA. The researchers also found that protein did contribute to changes in energy expenditure and lean body mass.—–“Obesity has become a major public health concern with more than 60 percent of adults in the United States categorized as overweight and more than 30 percent as obese,” according to background information in the article. The role of diet composition in response to overeating and energy dissipation is unclear.–George A. Bray, M.D., of the Pennington Biomedical Research Center, Baton Rouge, La., and colleagues conducted a study to determine whether the level of dietary protein differentially affected body composition, weight gain, or energy expenditure under tightly controlled conditions. The randomized controlled trial included 25 U.S. healthy, weight-stable male and female volunteers, ages 18 to 35 years, with a body mass index between 19 and 30. The first participant was admitted to the inpatient metabolic unit in June 2005 and the last in October 2007. After consuming a weight-stabilizing diet for 13 to 25 days, participants were randomized to receive diets containing 5 percent of energy from protein (low protein), 15 percent (normal protein), or 25 percent (high protein), which they were overfed during the last 8 weeks of their 10- to 12-week stay in the inpatient metabolic unit. Compared with energy intake during the weight stabilization period, the protein diets provided approximately 40 percent more energy intake, which corresponds to 954 calories a day.—All participants in the study gained weight and there were no differences by sex. The rate of weight gain in the low protein diet group was significantly less than in the other 2 groups (6.97 lbs. [3.16 kg] vs. 13.3 lbs [6.05 kg] for the normal protein diet group and 14.4 lbs [6.51 kg] in the high protein diet group).–“Body fat increased similarly in all 3 protein diet groups and represented 50 percent to more than 90 percent of the excess stored calories. Resting energy expenditure, total energy expenditure, and body protein did not increase during overfeeding with the low protein diet,” the authors write.-Lean body mass (body protein) decreased during the overeating period by 1.5 lbs. (0.70 kg) in the low protein diet group compared with a gain of 6.3 lbs. (2.87 kg) in the normal protein diet group and 7 lbs. (3.18 kg) in the high protein diet group. Resting energy expenditure (normal protein diet: 160 calories/day; high protein diet: 227 calories/day) increased significantly with the normal and high protein diets.-“In summary, weight gain when eating a low protein diet (5 percent of energy from protein) was blunted compared with weight gain when eating a normal protein diet (15 percent of energy from protein) with the same number of extra calories. Calories alone, however, contributed to the increase in body fat. In contrast, protein contributed to the changes in energy expenditure and lean body mass, but not to the increase in body fat,” the researchers write. “The key finding of this study is that calories are more important than protein while consuming excess amounts of energy with respect to increases in body fat.”

    Editorial: Overeating and Overweight — Extra Calories Increase Fat Mass While Protein Increases Lean Mass—-In an accompanying editorial, Zhaoping Li, M.D., Ph.D., and David Heber, M.D., Ph.D., of the University of California, Los Angeles, write that the results of this study “informs primary care physicians and policy makers about the benefits of protein in weight management.” “The results suggest that overeating low protein diets may increase fat deposition leading to loss of lean body mass despite lesser increases in body weight. Policy makers and primary care physicians need to understand the role of the Western diet in promoting overweight and obesity. Because this diet increases the risks of overnutrition through fat deposition beyond that detected by body mass index, the method used to assess the current obesity epidemic and the magnitude of the obesity epidemic may have been underestimated. Clinicians should consider assessing a patient’s overall fatness rather than simply measuring body weight or body mass index and concentrate on the potential complications of excess fat accumulation. The goals for obesity treatment should involve fat reduction rather than simply weight loss, along with a better understanding of nutrition science.” Story Source-The above story is reprinted from materials provided by JAMA and Archives Journals.

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    Cancer-Killing Compound Spares Healthy Cells- Lithocholic acid

    ScienceDaily (Jan. 4, 2012) — Lithocholic acid (LCA), naturally produced in the liver during digestion, has been seriously underestimated. A study published in the journal Oncotarget shows that LCA can kill several types of cancer cells, such as those found in some brain tumors and breast cancer.The research team, led by Concordia University, included scientists from McGill University and the Jewish General Hospital’s Lady Davis Institute in Montreal as well as the University of Saskatchewan.–Previous research from this same team showed LCA also extends the lifespan of aging yeast. This time, the team found LCA to be very selective in killing cancer cells while leaving normal cells unscathed. This could signal a huge improvement over the baby-with-the-bathwater drugs used in chemotherapy.–“LCA doesn’t just kill individual cancer cells. It could also prevent the entire tumor from growing,” says senior author Vladimir Titorenko, a professor in the Department of Biology and Concordia University Research Chair in Genomics, Cell Biology and Aging.–What’s more, LCA prevents tumors from releasing substances that cause neighboring cancer cells to grow and proliferate. Titorenko says LCA is the only compound that targets cancer cells, which could translate into tumor-halting power.–This is important for preventing cancer cells from spreading to other parts of the body,” he says, noting that unlike other anti-aging compounds, LCA stops cancer cell growth yet lets normal cells continue to grow.–A wide effect on different types of cancers –The next step for the research team will be to test LCA’s effect on different cancers in mice models. Titorenko expects that LCA will also kill cancer cells in those experiments and lead to human clinical trials. “Our study found that LCA kills not only tumors (neuroblastomas), but also human breast cancer cells,” says Titorenko. “This shows that it has a wide effect on different types of cancers.”–Titorenko emphasizes that unlike drugs used in chemotherapy, LCA is a natural compound that is already present in our bodies. Studies have shown that LCA can be safely administered to mice by adding it to their food. So why is LCA so deadly for cancer cells? Titorenko speculates that cancer cells have more sensors for LCA, which makes them more sensitive to the compound than normal cells.—LCA sensors send signals to mitochondria — the powerhouses of all cells. It seems that when these signals are too strong, mitochondria self-destruct and bring the cell down with them. Simply put, Titorenko and his colleagues engaged in cancer cell sabotage by targeting a weakness to LCA.–This study was supported by the Canadian Institutes of Health Research, the Natural Sciences and Engineering Research Council of Canada and the Concordia University Research Chair program.-Story Source-The above story is reprinted from materials provided by Concordia University. -Journal Reference–Goldberg AA, Beach A, Davies GF, Harkness TA, Leblanc A, Titorenko VI. Lithocholic bile acid selectively kills neuroblastoma cells, while sparing normal neuronal cells.. Oncotarget, 2011 Oct;2(10):761-82 [link]

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    Fountain of Youth in Bile- Longevity Molecule Identified

    (Bile Acids are Organic Acids that are a constituent of Bile – they occur primarily as Salts. Chemically, Bile Acids are classified as Steroids)

    Cholesterol is excreted from the body by Bile Acids. Bile Acids are the body’s only significant mechanism for the elimination of excess Cholesterol from the body. Bile Acids solubilize Cholesterol in the Bile, preventing the precipitation of Cholesterol in the Gallbladder.

    Bile Acids facilitate the digestion of Triglycerides from dietary Fats. Bile Acids function as emulsifying agents that render the Fatty Acids from dietary Triglycerides accessible to Pancreatic Lipase.

    Bile Acids facilitate the intestinal absorption of Fat-Soluble Vitamins.

    Immune System-Bile Acids may suppress Helicobacter pylori.

    New research has identified the role of a bile acid, called lithocholic acid, in extending the lifespan of normally aging yeast—ScienceDaily (Sep. 15, 2010) — The human quest for longer life may be one step closer, thanks to research from Concordia University. Published in the journal Aging, a new study is the first to identify the role of a bile acid, called lithocholic acid (LCA), in extending the lifespan of normally aging yeast. The findings may have significant implications for human longevity and health, as yeast share some common elements with people. “Although we found that LCA greatly extends yeast longevity, yeast do not synthesize this or any other bile acid found in mammals,” says senior author Vladimir Titorenko, Concordia University Research Chair in Genomics, Cell Biology and Aging and a professor in the Department of Biology. “It may be that yeast have evolved to sense bile acids as mildly toxic molecules and respond by undergoing life-extending changes. It is conceivable that the life-extending potential of LCA may be relevant to humans as well.”

    Over 19,000 small molecules screened

    Titorenko and colleagues screened more than 19,000 small molecules to test their ability to extend yeast-lifespan. Under both normal and stressed conditions, LCA had a major impact.–“Our findings imply that LCA extends longevity by targeting two different mechanisms,” says first author Alexander Goldberg, a Concordia doctoral student. “The first takes place regardless of the number of calories and involves the day-to-day or housekeeping proteins. The second system occurs during calorie-restriction and involves stressor proteins.”—“Regardless of their triggers both of these mechanisms work to suppress the pro-aging process,” he continues.– Bile acids may be beneficial to health—“Although we have an overall idea how LCA works to extend longevity in yeast, we still need to determine if this is the case for other species,” says Titorenko. “We do know from previous studies, however, that bile acids are beneficial to health and longevity. For example, they have shown to accumulate in the serum of long living mice and play a role in improving rodent liver and pancreatic function.”–“This leads us to believe that bile acids have potential as pharmaceutical agents for the treatment of diabetes, obesity and various metabolic disorders, all of which are age-related,” continues Titorenko. “They may indeed offer hope for a healthy aging life.”—This study was funded by the Canadian Institutes of Health Research, the Natural Sciences and Engineering Research Council of Canada, the Canada Foundation for Innovation and the Concordia University Chair Fund.—Story Source-The above story is reprinted from materials provided by Concordia University. –Journal References-Alexander A. Goldberg, Vincent R. Richard, Pavlo Kyryakov, Simon D. Bourque, Adam Beach, Michelle T. Burstein, Anastasia Glebov, Olivia Koupaki, Tatiana Boukh‐Viner, Christopher Gregg, Mylène Juneau, Ann M. English, Vladimir I. Titorenko and David Y. Thomas. Chemical genetic screen identifies lithocholic acid as an anti‐aging compound that extends yeast chronological life span in a TOR independent manner, by modulating housekeeping longevity assurance processes. Aging, 2010; 2 (7): 393 [link]–Alexander A. Goldberg, Pavlo Kyryakov, Simon D. Bourque and Vladimir I. Titorenko. Xenohormetic, hormetic and cytostatic selective forces driving longevity at the ecosystemic level. Aging, 2010; 2 (8): 461-470 [link]

     

    Show Of The Week January 13 2012

     

    Taurine increases bile acid pool size and reduces bile saturation index In the hamster

    Dietary Taurine Enhances Cholesterol Degradation and Reduces Serum and Liver Cholesterol

    High Dietary Taurine Reduces Apoptosis and Atherosclerosis in the Left Main Coronary Artery

    Leaked– US to Start ‘Trade Wars’ with Nations Opposed to Monsanto, GMO Crops

    How to Oxygenate yourself

    Hydrogen Peroxide Benefits and Data

     

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    Taurine increases bile acid pool size and reduces bile saturation index In the hamster

    S Bellentani,
    M Pecorari,
    P Cordoma,
    P Marchegiano,
    F Manenti,
    E Bosisio,
    E De Fabiani and
    G Galli
    + Author Affiliations

    Chair of Gastroenterology, University of Modena, Italy.
    Abstract

    There is evidence that increased availability of taurine enhances the proportion of taurine-conjugated bile acids in bile. To explore the possibility that taurine treatment could also influence hepatic cholesterol and bile acid metabolism, we fed female hamsters for 1 week and measured both the biliary lipid content and the microsomal level of the rate-limiting enzymes of cholesterol and bile acid synthesis. In these animals the cholesterol 7 alpha-hydroxylase activity was significantly greater in respect to controls (P less than 0.05). The total HMG-CoA reductase activity, as well as that of the active form, was similarly increased. The stimulation of 7 alpha-hydroxycholesterol synthesis was associated with an expansion of the bile acid pool size in taurine-fed animals. Taurine feeding was observed to induce an increase in bile flow as well as in the rate of excretion of bile acids, whereas the secretion rate of cholesterol in bile was decreased. As a consequence, the saturation index was significantly lower in taurine-fed animals (P less than 0.05). The possible mechanisms through which taurine exhibits the modification of the enzyme activities and of the biliary lipid composition are discussed.

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    Dietary Taurine Enhances Cholesterol Degradation and Reduces Serum and Liver Cholesterol Concentrations in Rats Fed a High-Cholesterol Diet1

    Hidehiko Yokogoshi*2, Hideki Mochizuki*, Ken Nanami*, Yuko Hida*, Fuyuko Miyachi† and Hiroaki Oda†

    ; * ; School of Food and Nutritional Sciences, The University of Shizuoka, Shizuoka 422-8526, Japan and; † ; Department of Applied Biological Sciences, Nagoya University, Nagoya 464-8601, Japan

    2To whom correspondence and reprint requests should be addressed.

    The effect of taurine on hypercholesterolemia induced by feeding a high-cholesterol (HC) diet (10g/kg) to rats was examined. When various amounts of taurine (0.25, 0.5, 1, 2.5, 5, 10, 20, 30, 40 or 50 g/kg diet) were supplemented to HC for 2 wk, serum total cholesterol gradually and significantly decreased in a dose-dependent manner and normalized at the dose of 10 g taurine/kg, compared with the control (cholesterol free) diet group. By contrast, serum HDL-cholesterol was elevated by taurine supplementation. The HC diet caused a significant decrease in the concentration of taurine in serum, liver and heart compared to that in the control group, and the effective dose of supplemental taurine to improve its reduction was 2.5 g/kg diet. In the hypercholesterolemic rats fed the HC diet, the excretion of fecal bile acids and hepatic cholesterol 7 α-hydroxylase (CYP7A1) activity and its mRNA level increased significantly, and the supplementation of taurine further enhanced these indexes, indicating an increase in cholesterol degradation. The abundance of mRNA for Apo A-I, one of the main components of HDL, was reduced by HC and recovered by taurine supplementation. Agarose gel electrophoresis revealed that, in hypercholesterolemic rats fed the HC diet, the serum level of the heavier VLDL increased significantly, but taurine repressed this increase and normalized this pattern. Significant correlations were observed between the time- and dose-dependent increases of CYP7A1 gene expression and the decrease of blood cholesterol concentration in rats fed the HC diet supplemented with taurine (time, r = -0.538, P < 0.01, n = 32; dose, r = -0.738, P < 0.001, n = 20). These results suggest that the hypocholesterolemic effects of taurine observed in the hypocholesterolemic rats fed the HC diet were mainly due to the enhancement of cholesterol degradation and the excretion of bile acid.

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    High Dietary Taurine Reduces Apoptosis and Atherosclerosis in the Left Main Coronary Artery—-Association With Reduced CCAAT/Enhancer Binding Protein Homologous Protein and Total Plasma Homocysteine but not Lipidemia

    Anthony Zulli,
    Eza Lau,
    Bagus P.P. Wijaya,
    Xin Jin,
    Komang Sutarga,
    Grace D. Schwartz,
    Jonathon Learmont,
    Peter J. Wookey,
    Angelo Zinellu,
    Ciriaco Carru,
    David L. Hare
    + Author Affiliations

    From the Departments of Cardiology (A.Z., E.L., B.P.P.W., X.J., K.S., G.D.S., J.L., P.J.W., D.L.H.) and Medicine (A.Z., D.L.H.), University of Melbourne, Austin Health, Heidelberg, Australia; and the Department of Biomedical Sciences (A.Z., C.C.), University of Sassari Viale S Pietro, Sassari, Italy.
    Correspondence to Anthony Zulli, Vascular Laboratory, Department of Cardiology, Austin Health, Heidelberg, Australia. E-mail azulli@unimelb.edu.au
    Abstract

    We sought to determine whether taurine could specifically protect against coronary artery disease during an atherogenic diet and whether taurine affects the lipid profile, metabolites of methionine, and endothelial atherogenic systems. Rabbits were fed one of the following diets for 4 weeks: (1) control diet; (2) 0.5% cholesterol+1.0% methionine; or (3) 0.5% cholesterol+1.0% methionine+2.5% taurine. Endothelial function was examined, and the left main coronary artery atherosclerosis was quantified by stereology and semiquantitative immunohistochemistry to determine the endothelial expression of proteins related to the NO, renin-angiotensin, endoplasmic reticulum, and oxidative stress systems, as well as apoptosis. Taurine normalized hyperhomocysteinemia (P<0.05) and significantly reduced hypermethioninemia (P<0.05) but not lipidemia. The intima:media ratio was reduced by 28% (P=0.034), and atherosclerosis was reduced by 64% (P=0.012) and endothelial cell apoptosis by 30% (P<0.01). Endothelial cell CCAAT/enhancer binding protein homologous protein was normalized (P<0.05). Taurine failed to improve hyperlipidemia, endothelial function, or endothelial proteins related to the NO, renin-angiotensin, and oxidative stress systems. Taurine reduces left main coronary artery wall pathology associated with decreased plasma total homocysteine, methionine, apoptosis, and normalization of CCAAT/enhancer binding protein homologous protein. These results elucidate the antiapoptotic and antiatherogenic properties of taurine, possibly via normalization of endoplasmic reticulum stress.

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    Leaked– US to Start ‘Trade Wars’ with Nations Opposed to Monsanto, GMO Crops

    The United States is threatening nations who oppose Monsanto’s genetically modified (GM) crops with military-style trade wars, according to information obtained and released by the organization WikiLeaks. Nations like France, which have moved to ban one of Monsanto’s GM corn varieties, were requested to be ‘penalized’ by the United States for opposing Monsanto and genetically modified foods. The information reveals just how deep Monsanto’s roots have penetrated key positions within the United States government, with the cables reporting that many U.S. diplomats work directly for Monsanto. The WikiLeaks cable reveals that in late 2007, the United States ambassador to France and business partner to George W. Bush, Craig Stapleton, requested that the European Union along with particular nations that did not support GMO crops be penalized. Stapleton, who co-owned the Dallas/Fort Worth-based Texas Rangers baseball team with Bush in the 1990s, stated–“Country team Paris recommends that we calibrate a target retaliation list that causes some pain across the EU since this is a collective responsibility, but that also focuses in part on the worst culprits. The list should be measured rather than vicious and must be sustainable over the long term, since we should not expect an early victory. Moving to retaliation will make clear that the current path has real costs to EU interests and could help strengthen European pro-biotech voices.”

    The Leaked Political Agenda Behind Monsanto’s GMO Crops

    The ambassador plainly calls for ‘target retaliation’ against nations who are against using Monsanto’s genetically modified corn, admittedly linked to organ damage and environmental devastation. Amazingly, this is not an isolated case. In similar newly released cables, United States diplomats are found to have pushed GMO crops as a strategic government and commercial imperative. Furthermore, the U.S. specifically targeted advisers to the pope, due to the fact that many Catholic bishops and figureheads have openly denounced GMO crops. In fact, the Vatican has openly declared Monsanto’s GMO crops as a ‘new form of slavery’.[U1] “A Martino deputy told us recently that the cardinal had co-operated with embassy Vatican on biotech over the past two years in part to compensate for his vocal disapproval of the Iraq war and its aftermath – to keep relations with the USG [US government] smooth. According to our source, Martino no longer feels the need to take this approach,” says the cable.—Perhaps the most shocking piece of information exposed by the cables is the fact that these U.S. diplomats are actually working directly for biotech corporations like Monsanto. The cables also highlight the relationship between the U.S. and Spain in their conquest to persuade other nations to allow for the expansion of GMO crops. Not only did the Spanish government secretly correspond with the U.S. government on the subject, but the U.S. government actually knew beforehand how Spain would vote before the Spanish biotech commission reported their decision regarding GMO crops. The cable states–“In response to recent urgent requests by [Spanish rural affairs ministry] state secretary Josep Puxeu and Monsanto, post requests renewed US government support of Spain’s science-based agricultural biotechnology position through high-level US government intervention.”—-Monsanto has undoubtedly infiltrated the United States government in order to push their health-endangering agenda, and this has been known long before the release of these WikiLeaks cables. The U.S. is the only place where Monsanto’s synthetic hormone Posilac is still used in roughly 1/3 of all cows, with 27 nations banning the substance over legitimate health concerns. Despite Monsanto’s best attempts at incognito political corruption, nothing can stop the grassroots anti-Monsanto movement that is taking over cities and nations alike

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    How to Oxygenate yourself

    Oxygenate—when you see heavy dosing of chem. Trails you may want to use “ Rocket Fuel” as some call it in science or Hydrogen Peroxide—if you have food grade—take 1-3 drops in a 1 ounce container—add distilled water and then attach a mister or a spray nozzle—and every so often give your self a pump this will release or increase Oxygen into the blood stream and take a load off the heart—and increase oxygen circulation throughout the body—

    When doing this as well Increase Vitamin C intake ( 5 grams plus) to offset any prooxidant effect of the H2O2

    ORRR got to a dollar store and get a Peroxide without stabilzers—and add the whole thing to a one ounce bottle and add a mister to it and apply as been mentioned in the above paragraph—this will again offset any potential issue that may occur as a lack of Oxygen

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    Hydrogen Peroxide Benefits and Data

    Pure Hydrogen Peroxide, discovered by a French chemist in 1818 was utilized extensively from the early 19th century until the early 20th Century as a treatment of various illnesses such as; asthma, cholera, syphilis, typhoid fever, tuberculosis, ulcers and pertussis. Food Grade Hydrogen Peroxide is approved by the United States Department of Agriculture as it contains no harmful additives.

    The use of Hydrogen Peroxide Treatment lost a great deal of its appeal with the introduction of the pharmaceutical industry in the 20th Century. With the increased knowledge of several of the side effects produced by taking today’s prescribed medicines, a lot of individuals are reverting back to the use of the older, conventional cures including Hydrogen Peroxide Treatment, also called Oxygen Therapy.

    Hydrogen Peroxide was utilized following the First World War to fight a pneumonia pandemic. It was, and still is, used extensively to treat emphysema and congestive lung problems. The main benefit is due to its ability to increment the oxygen content of blood and body tissue which increases blood flow and raises body temperature.

    Some of the medical uses of Food Grade Hydrogen Peroxide contain:

    Cuts, Scrapes and Open Sores -This is the old conventional treatment for open cuts and sores. The procedure consists of applying Hydrogen Peroxide to kill any infection.

    Acne – Applied with a cotton swob it will dehydrate the acne. A moisturizer ought to be applied afterwards to restore some of the natural moisture of the skin as the Hydrogen Peroxide will dry the area encompassing the acne.

    Mouthwash – A mild solution may be used as a mouthwash. This will kill bacteria that causes bad breath as well as help prevent Periodontal disease. Simultaneously it will whiten your teeth.

    Take away Ear Wax – A weak solution put in your ear will aid in the removal of set ear wax.

    Athletes Feet – You could use a spray bottle to apply to affected areas of the feet. This will kill off the fungus causing the athletes feet.

    Colds, Flu – Gargling a weak solution will kill off the germs causing these illnesses.

    Some Non-medical, family uses, include:

    Stain Remover – Amazing for removing blood stains.

    Sanitizer – Utilize it in the kitchen and bathroom to sanitize and clean all surfaces.

    Wash Vegetables – Vegetables are sprayed with all types of insecticides and additives to keep them fresh. Rinsing them off with a solution of Hydrogen Peroxide will kill off these harmful additives.

    Water Plants – Utilized to provide extra oxygen to the soil. Numerous farmers now spray a weak solution on their crops to remove harmful bacteria and act as a natural insecticide.

    Treat Fungus – Wash moldy places with Hydrogen Peroxide.

    Hydrogen Peroxide is likely one of the best and least expensive products on the market nowadays that can be utilized in a lot of areas. Everybody should have a bottle on hand at all times and utilize it wherever harmful bacteria is present.

    Utilize it with care and utilize it often

    Read more: http://www.articlesbase.com/health-articles/benefits-and-many-uses-of-food-grade-hydrogen-peroxide-4201698.html#ixzz1KriOiqjM
    Under Creative Commons License: Attribution

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    [U1]The Irony Here is that Own Monsanto—so this is a smoke screen to distance themselves as to save Face among there 1 billion catholics—if they knew that there own religion was forming a genocide on the membership they would be outraged—this would disassociate them from the institution
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    Show of the Week January 16 2012

     

     

    Does Sugar Feed Cancer?

    Cancer Cells Feed On Sugar-Free Diet

    Statins linked with small diabetes risk

    Rare ‘supersoldier’ ants created in Canadian lab

    These Substances may Enhance Hair Growth -if Hair Follicles are still Alive

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    Does Sugar Feed Cancer?

    ScienceDaily (Aug. 17, 2009) — Researchers at Huntsman Cancer Institute at the University of Utah have uncovered new information on the notion that sugar “feeds” tumors. The findings may also have implications for other diseases such as diabetes. The research is published in the journal Proceedings of the National Academy of Sciences.–“It’s been known since 1923 that tumor cells use a lot more glucose than normal cells. Our research helps show how this process takes place, and how it might be stopped to control tumor growth,” says Don Ayer, Ph.D., a Huntsman Cancer Institute investigator and professor in the Department of Oncological Sciences at the University of Utah.-During both normal and cancerous cell growth, a cellular process takes place that involves both glucose (sugar) and glutamine (an amino acid). Glucose and glutamine are both essential for cell growth,[U1] and it was long assumed they operated independently, but Ayer’s research shows they are inter-dependent. He discovered that by restricting glutamine availability, glucose utilization is also stopped. “Essentially, if you don’t have glutamine, the cell is short circuited due to a lack of glucose, which halts the growth of the tumor cell” Ayer says.–The research, spearheaded by Mohan Kaadige, Ph.D., a postdoctoral fellow in Ayer’s lab, focused on MondoA, a protein that is responsible for turning genes on and off. In the presence of glutamine, MondoA blocks the expression of a gene called TXNIP. TXNIP is thought to be a tumor suppressor, but when it’s blocked by MondoA , it allows cells to take up glucose, which in turn drives tumor growth. Ayer’s research could lead to new drugs that would target glutamine utilization, or target MondoA or TXNIP.–Ayer says the next step in his research is to develop animal models to test his ideas about how MondoA and TXNIP control cell growth. “If we can understand that, we can break the cycle of glucose utilization which could be beneficial in the treatment of cancer,” Ayer says.–Story Source–The above story is reprinted from materials provided by University of Utah Health Sciences, via EurekAlert!, a service of AAAS.

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    Cancer Cells Feed On Sugar-Free Diet

    ScienceDaily (Jan. 10, 2012) — Cancer cells have been long known to have a “sweet tooth,” using vast amounts of glucose for energy and for building blocks for cell replication.—Now, a study by a team of researchers at Johns Hopkins and elsewhere shows that lymph gland cancer cells called B cells can use glutamine in the absence of glucose for cell replication and survival, particularly under low-oxygen conditions, which are common in tumors.—Writing in the Jan. 4, 2012, edition of Cell Metabolism, Anne Le, M.D., and a team of investigators collaborating with the Johns Hopkins Brain Science Institute, say the finding is critical for developing innovative cancer therapies because it offers “proof of concept” evidence that curbing the growth of B cell cancers can be accomplished by inhibiting a glutamine enzyme called glutaminase.–Le notes that although little is known about glutamine’s role in the growth of B cell cancer, the amino acid circulates in the blood at the highest level among the 20 amino acids that do so.–The tricarboxylic acid cycle (TCA or Krebs cycle) is classically regarded as a pathway for glucose oxidation. However, the experiments by Le and the team show that B cells oxidize glutamine when glucose is absent.—The study also found that when oxygen is scarce, there is enhanced conversion of glutamine to glutathione, an important agent for controlling the accumulation of oxygen-containing chemically reactive molecules that cause damage to normal cells.—When the investigators used a glutaminase inhibitor, cancerous growth of B cells was stopped in petri dishes.—“The flexibility of the TCA cycle in using both glutamine and glucose pathways may be important for cancer cells to proliferate and survive, especially under the low-oxygen and nutrient-deprived conditions often encountered in the tumor microenvironment,” says Le.–Now, perhaps, scientists can exploit that survival strategy to stop cancer, according to former Johns Hopkins scientist Chi Dang, M.D., now at the Abramson Cancer Center at the University of Pennsylvania. “A broader and deeper understanding of cancer cell metabolism and cancer cells’ability to reprogram biochemical pathways under metabolic stress can be a rich ground for therapeutic approaches targeting tumor metabolism,” he says.—In addition to Le, an assistant professor in the Department of Pathology at the Johns Hopkins University School of Medicine, other researchers from Johns Hopkins who participated in this study include Sminu Bose, Arvin Gouw, Joseph Barbi, Takashi Tsukamoto, Camilo J. Rojas and Barbara Slusher. The Johns Hopkins Brain Science Institute, where Tsukamoto, Rojas and Slusher are faculty, is pursuing the development of new glutaminase inhibitor drugs.—Story Source-The above story is reprinted from materials provided by Johns Hopkins Medicine. –Journal Reference–Anne Le, Andrew N. Lane, Max Hamaker, Sminu Bose, Arvin Gouw, Joseph Barbi, Takashi Tsukamoto, Camilio J. Rojas, Barbara S. Slusher, Haixia Zhang, Lisa J. Zimmerman, Daniel C. Liebler, Robbert J.C. Slebos, Pawel K. Lorkiewicz, Richard M. Higashi, Teresa W.M. Fan, Chi V. Dang. Glucose-Independent Glutamine Metabolism via TCA Cycling for Proliferation and Survival in B Cells. Cell Metabolism, 2012; 15 (1): 110 DOI: 10.1016/j.cmet.2011.12.009

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    Statins linked with small diabetes risk

    Whether statins can make blood sugar rise enough that someone crosses the threshold to diabetes has been confusing. -A new side-effect seems to be emerging for those cholesterol-lowering wonder drugs called statins: They may increase some people’s chances of developing Type 2 diabetes.–A study adds to the evidence, finding a modest risk among older women who used a variety of statins. It’s a puzzling link, and specialists say people who most need statins because of a high risk for a heart attack should stick with the drugs.-“What I fear here is that people who need and will benefit from statins will be scared off of using the drugs because of reports like this,” says Dr. Steven Nissen, cardiology chairman at the Cleveland Clinic, who wasn’t involved with the research. “We don’t want these drugs in the water supply, but we want the right people treated[U2]. When they are, this effect is not a significant limitation.”–But more and more doctors are urging otherwise healthy people to use the pills as a way to prevent heart disease[U3]. For them, the findings add another potential complication as they consider whether to tackle their cholesterol with diet and exercise alone or add a medication.-“The statin should not be seen as the magic pill,”[U4] says Dr. Yunsheng Ma of the University of Massachusetts Medical School, who led Monday’s study of postmenopausal women.

    Heart risks of diabetes

    Statins are one of the most widely prescribed drugs, and among the most touted with good reason. They can dramatically lower so-called “bad” LDL cholesterol. Studies make clear that they save lives when used by people who already have heart disease.–What’s debated is how much the drugs help people who don’t yet have cardiovascular disease but whose chances are higher because of other factors such as smoking or high blood pressure — or diabetes.—In fact, long-term diabetes is so heart-risky that the American Diabetes Association urges fairly aggressive statin use by many diabetics. For everyone else, Nissen says the general rule is statins help people who have at least a 10 per cent chance of a heart attack in the next 10 years, something a doctor can calculate.

    All drugs have side-effects that are important to consider while deciding whether they’re a good bet for an individual. Statins have long been known to cause muscle pain that on rare occasions becomes a serious breakdown of muscle that can lead to kidney failure, even death.—Not to mention RNA damage—and lobotomizing the brain as well—But whether statins can make blood sugar rise enough that someone crosses the threshold to diabetes has been confusing.–After all, some of the same risks for heart disease — such as being overweight and sedentary — also increase the odds of developing Type 2 diabetes. And Ma says too many statin users wrongly assume the pills will let them eat whatever they want.

    Ma’s team examined a huge government study that tracked the health of postmenopausal women for many years. They culled the records of more than 153,000 women who didn’t have diabetes when they enrolled in the Women’s Health Initiative in the 1990s. Just 7 per cent were taking statins at the time. Fast forward to 2005: Nearly 10 per cent of the statin users had developed diabetes as a needed note of caution for women, saying there’s less certainty about the drugs’ overall effects in them. Stay tuned: Her own research aims to narrow down which statin users are more likely to experience a blood-sugar jump.

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    Rare ‘supersoldier’ ants created in Canadian lab

    Read 178 comments178

    McGill Unversity researchers were able to create supersoldier ants, which are a biological anomaly, in the lab. (Alex Wilder/alexanderwilder.com)

    As It Happens on super soldier ants8:09

    Canadian researchers have discovered how to make a certain kinds of ants develop into “supersoldiers”[U5] with huge oblong heads and giant vicious jaws.–The findings are significant because they show there is dormant genetic potential that can be invoked by changes in the environment and locked in place for a very long time, said lead author Ehab Abouheif, a McGill University biology professor, whose research was published Friday in the journal Science.–The authors suggest that hanging on to ancestral developmental toolkits can be an important way for organisms to evolve new physical traits.–“Birds with teeth, snakes with fingers and humans with ape-like hair – these are ancestral traits that pop regularly in nature,”[U6] Abouheif said. “But for the longest time in evolutionary theory, these ancestral traits were thought to go nowhere … the Barnum and Bailey of evolution. So they’ve been an unappreciated source of evolutionary variation.”—Typically, supersoldier ants are biological anomalies that occur rarely in nature and only in limited geographical regions. But the McGill researchers found these supersoldiers in unexpected regions and also created them by manipulating hormones.—Pheidole (big-headed) ant colonies contain millions of ants, including minor workers and soldiers. Depending on the food ants are fed, certain hormones are triggered in the ant larvae and they either develop into soldiers or minor workers.–Then there are supersoldier ants that block their nest entrance with their extra-large heads and fight with invading ants during army ant raids.–Abouheif and his team unexpectedly found supersoldier ants in the Pheidole species in Long Island where they aren’t normally seen. They were then able to artificially induce them in the lab by by dabbing the larvae with juvenile hormone, indicating that environmental cues can switch on the genetic machinery that produces supersoldiers.[U7]–“The kind of environmental stressors that evoke this dormant potential are there all the time, so when the need arises natural selection can take hold of the potential and actualize it,” said Abouheif.—“So what we’re showing is that environmental stress is important for evolution because it can facilitate the development of novel phenotypes. Any time you have a mismatch between the normal environment of the organism and its genetic potential you can release them – and these things can be locked in place for 30 to 65 million year

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    [U1]Glutamine Breaks down into 5 different amino acids and is the most abundant amino in the oesophagus-and intestine and stomach regions—it will converto to gaba-glutationie-glycine-glutamic acid and ghb—the glycine converts to glucagons( sugar ) which is required fro brain and liver and cellular energy
    [U2]“the right People/”” this is amazing these drugs are so damaging from the genetic code to the arterial integrity-RNA DNA damage—brain lobotomizing—who are these “ right people?
    [U3]This is unbelievable and the ignorance is what this report is showing the medical field is doing to healthy individuals to compromise there health
    [U4]First we are going to use a s preventative and now we are not to look at it as a magical pill
    [U5]Welcome to Canada EH!!! The land of Biodiversity and death—we export Nuclear energy ( bombs) food ( GMO WHEAT AND CANOLA ..ETC ) andd Now Pestilence–
    [U6]Genetic engineering experiments—anomalies created in a lab
    [U7]In other words they created these ants and put them on Long Island and were able to manipulate the Genetic code of these bugs—meaning we are now heading for a new Bio Warfare –we will just create a Super bug to inflict a people or Undesirables we do not want—we will give an ant a poison bite a butterfly with a knoxious sting –a flea to carry MRSA—etc.
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    First Link Between Potentially Toxic PFCs in Office Air and in Office Workers’ Blood

    ScienceDaily (Jan. 18, 2012) — In a first-of-its-kind study, scientists are reporting that the indoor air in offices is an important source of worker exposure to potentially toxic substances released by carpeting, furniture, paint and other items. Their report, which documents a link between levels of these so-called polyfluorinated compounds (PFCs) in office air and in the blood of workers, appears in ACS’ journal Environmental Science & Technology.—-Michael McClean and colleagues explain that PFCs, used in water-repellent coatings on carpet and furniture, may have adverse effects on human health. The substances are widespread in the environment and in humans around the world. Scientists know that potential sources of exposure include food, water, indoor air, indoor dust and direct contact with PFC-containing objects. But the link between levels in air and blood had not been explored previously, so McClean’s group set out to fill that gap with a study of 31 office workers in Boston.—They found concentrations of a PFC called fluorotelomer alcohol (FTOH) in office air that were 3-5 times higher than those reported in previous studies of household air, “suggesting that offices may represent a unique and important exposure environment.” In addition, the study found a strong link between concentrations of FTOH in office air and perfluorooctanoic acid (a metabolite of FTOH) in the blood of office workers. The results also suggested that workers in newly renovated office buildings may receive considerably higher doses of PFCs than workers in older buildings.–The authors acknowledge funding from the National Institute of Environmental Health Sciences. –Story Source–The above story is reprinted from materials provided by American Chemical Society. —Note: Materials may be edited for content and length. For further information, please contact the source cited above.—-Journal Reference-Alicia J. Fraser, Thomas F. Webster, Deborah J. Watkins, Jessica W. Nelson, Heather M. Stapleton, Antonia M. Calafat, Kayoko Kato, Mahiba Shoeib, Verónica M. Vieira, Michael D. McClean. Polyfluorinated Compounds in Serum Linked to Indoor Air in Office Environments. Environmental Science & Technology, 2012; 46 (2): 1209 DOI: 10.1021/es2038257

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    Short, Sharp Shock Treatment for E. Coli

    ScienceDaily (Jan. 11, 2012) — A short burst of low voltage alternating current can effectively eradicate E. coli bacteria growing on the surface of even heavily contaminated beef, according to a study published in the International Journal of Food Safety, Nutrition and Public Health. The technique offers an inexpensive and easy to implement approach to reducing the risk of food poisoning, which can occur despite handlers complying with hygiene standards.—Food poisoning is a serious public-health issue, especially with the emergence of lethal and highly virulent strains of Escherichia coli (E. coli O157:H7, for example). Infection with this bacterium causes serious diarrhea, dehydration, kidney problems and can lead to serious long-term problems or even be fatal in children, the elderly and people with pre-existing health problems. Tens of thousands of people are affected by E. coli infection each year through eating contaminated beef and other food products. The US Centers for Disease Control and Prevention (CDC) estimates that about 2500 people are hospitalized and there are several dozen deaths each year.—Now, Ajit Mahapatra and colleagues at Fort Valley State University, in Georgia and Virginia Tech have demonstrated that applying a low-voltage alternating current to beef samples inoculated with large numbers of the potentially lethal E. coli O157:H7 can almost completely deactivate the bacterium, which is usually present on the surface of contaminated meat. The team points out that the level of contamination used in their tests far exceeded the contamination that would be seen in commercial carcasses after slaughter.—Previous researchers had demonstrated that electricity can kill bacteria effectively. The study by Mahapatra and colleagues proves efficacy against E. coli O157:H7 at low voltage and low alternating current. It offers a quick and easy way to decontaminate at-risk, but otherwise safe beef without recourse to microbicidal chemicals or other more complicated treatment processes.—Story Source-The above story is reprinted from materials provided by Inderscience Publishers, via EurekAlert!, a service of AAAS. –Note: Materials may be edited for content and length. For further information, please contact the source cited above.—Journal Reference-Donna L. Harris, Ajit K. Mahapatra, Baron L. Jones, Govind Kannan. Efficacy of low-voltage AC for inactivating surface adherent Escherichia coli O157:H7 on beef. International Journal of Food Safety, Nutrition and Public Health, 2011; 4 (2/3/4): 214 DOI: 10.1504/IJFSNPH.2011.044624

    SPECIAL NOTE—Remedy—So it would appear running A small cuurent of electricity to you foods may in fact assist in the prevention of pathogens that may infact creat a proble—so a good zapper or even a stunner set to low may in fact kill off any thing in the meats you are about to prepare

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    Dietary DHA Linked to Male Fertility

    ScienceDaily (Jan. 9, 2012) — Who knew that male fertility depends on sperm-cell architecture? A University of Illinois study reports that a certain omega-3 fatty acid is necessary to construct the arch that turns a round, immature sperm cell into a pointy-headed super swimmer with an extra long tail.—“Normal sperm cells contain an arc-like structure called the acrosome that is critical in fertilization because it houses, organizes, and concentrates a variety of enzymes that sperm use to penetrate an egg,” said Manabu Nakamura, a U of I associate professor of biochemical and molecular nutrition.—The study shows for the first time that docosahexaenoic acid (DHA) is essential in fusing the building blocks of the acrosome together. “Without DHA, this vital structure doesn’t form and sperm cells don’t work,” said Timothy Abbott, a doctoral student who co-authored the study.–Men concerned about their fertility may wonder what foods contain DHA. Marine fish, such as salmon or tuna, are excellent sources of this omega-3 fatty acid.[U1]–The scientists became intrigued with DHA’s role in creating healthy sperm when they experimented with “knockout” mice that lack a gene essential to its synthesis. “We looked at sperm count, shape, and motility, and tested the breeding success rate. The male mice that lacked DHA were basically infertile,” Nakamura said.—But when DHA was introduced into the mice’s diet, fertility was completely restored. “It was very striking. When we fed the mice DHA, all these abnormalities were prevented,” he said.—The scientists then used confocal laser scanning (3D) microscopy to look at thin slices of tissue in progressive stages of a sperm cell’s development. By labeling enzymes with fluorescence, they could track their location in a cell.–“We could see that the acrosome is constructed when small vesicles containing enzymes fuse together in an arc. But that fusion doesn’t happen without DHA,” he said.–In the absence of DHA, the vesicles are formed but they don’t come together to make the arch that is so important in sperm cell structure, he noted.–Nakamura finds the role this omega-3 fatty acid plays in membrane fusion particularly exciting. Because DHA is abundant in specific tissues, including the brain and the retina as well as the testes, the scientists believe their research findings could also impact research relating to brain function and vision.–“It’s logical to hypothesize that DHA is involved in vesicle fusion elsewhere in the body, and because the brain contains so much of it, we wonder if deficiencies could play a role, for example, in the development of dementia. Any communication between neurons in the brain involves vesicle fusion,” he noted.–The Illinois scientists will continue to study sperm; meanwhile, Nakamura has sent some of his DHA-deficient knockout mice to other laboratories where scientists are studying DHA function in the brain and the retina.–This work was supported in part by a CONACyT Mexico fellowship award.–Story Source-The above story is reprinted from materials provided by University of Illinois College of Agricultural, Consumer and Environmental Sciences. The original article was written by PhyllisPicklesimer. -Journal Reference-M. Roqueta-Rivera, T. L. Abbott, M. Sivaguru, R. A. Hess, M. T. Nakamura. Deficiency in the Omega-3 Fatty Acid Pathway Results in Failure of Acrosome Biogenesis in Mice. Biology of Reproduction, 2011; 85 (4): 721 DOI: 10.1095/biolreprod.110.089524

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    Pesticide Illnesses and GM Soybeans-Ban on Aerial Spraying Demanded in Argentina

    Coalition of doctors, health professionals and researchers demand ban on aerial spraying based on evidence documenting increase in pesticide-related illnesses since the introduction of GM soya. Dr Eva Sirinathsinghji——A network of 160 physicians, health workers and researchers in Argentina are demanding a ban on aerial spraying of pesticides based on increases in cancer and a range of pesticide-related illnesses since the introduction of genetically modified (GM) soybeans. These illnesses affect development, reproduction, the skin, as well as the immune, respiratory, neurological, and endocrine systems.–The network met in August 2010 [1] and again in 2011[2]. Following the 2010
    meeting an important report was compiled linking agrochemical exposure to significant increase in illnesses including birth defects and cancers in and around areas where agrochemicals are used. Increasing illness parallels the introduction and spread of GM soybeans tolerant to Monsanto’s glyphosate-based herbicide, Roundup. —-The striking link between illness and pesticide use presented at the first meeting led the Network Of Physicians Of Drop-Sprayed Towns to propose a complete ban on all aerial sprayings of pesticides, a complete ban of pesticides of toxicological types Ia (defined as extremely hazardous) and Ib (highly hazardous), and a ban on other pesticide use within 1 kilometre of residential areas. They also questioned the current agro-industrial and transgenic production model, stating that other options for agro-ecological production should be promoted and developed by the State University.–The second meeting called on local and national government to ensure people’s right to good health instead of the rights of agribusiness and private proprietors that currently prevail, and repeated their call for a complete ban on aerial spraying.—The Argentinean communities’ fight for judicial, healthcare and governmental
    recognition for health problems associated with pesticide use goes back 10 years. A summary compiled by non-governmental organisations and community residents is contained in the ‘Declaration of Caroya’. It documents [3] the “reduction in the average age and height” of residents in crop-sprayed towns “due to malnutrition”, and “decrease of the body’s natural defences.” In addition, “birth defects, mutagenesis, miscarriages, depression and suicide, disorders of the central nervous system and other neurological pathologies; disabilities, spina bifida, lupus, leukemia and other types of cancers; chloracne and other skin problems; asthma, allergies, and other respiratory and lung-related problems; male sterility and impotence; hormonal disruption and other hormonal disorders; diminished childhood development; prolonged febrile syndrome without focus; children’s increased vulnerability to pollutants; anemia, multiple sclerosis, cerebral ischemia, death..[U2]”—Alarming increases in birth defects, cancers, and other illnesses Public health officials have ignored ‘alarming notes coming from healthcare officials’ and consequently, very few epidemiological studies have been conducted. However the physicians (most of whom have been serving the same populations for over 25 years) have striking observational data that correlated with presentations and stories from people in the communities for a range of diseases associated with agrochemical exposure. They highlighted a systematic link between the unusual observations of recent years with this exposure. –The province of Chaco, where Dr Maria del Carmen Serveso heads a hospital intensive care unit, presented a devastating overview of rising illnesses in many towns. The illnesses include renal failure, birth defects in children of young mothers, cancers even in very young people, miscarriages, difficulty in becoming pregnant, respiratory problems and acute allergies; [U3]all linked by health teams to chemical contamination from agroindustrial farming recently imposed on the area replacing small-scale cotton farming and native forests. Respiratory illnesses were found to correlate with paraquat exposure.– One of the few epidemiological studies performed by Dr Gladys Trombotto, a geneticist from the University of Cordoba Maternity and Neonatal Unit, assessed 110 000 births over 10 years, and found a 2- and 3-fold increase in congenital and musculoskeletal defects respectively between 1971 and 2003 [4]. Child cancer data presented by Dr Otaño backed up what other physicians found in their own observations – incidence of birth defect rates increased significantly. He recorded 15.7 cases/100 000 in 2007 compared with the pre-existent level of 10.5 cases/100 000 in 1985—. The strong correlation of pesticide exposure with incidence of illness was exemplified by the observation made in 2005 by members of the Córdoba’s Ituzaingó neighbourhood, showing a higher rate of cancer in residents living closer to the fields that are sprayed. — The doctors suspect that the scale of damage to human health caused by agrochemicals is not fully recognized. The numbers of miscarriages may be higher than recorded levels, and other neurological and psychological problems are not currently being assessed. Preliminary and small-scale tests of children under a year of age suggest the existence of such illnesses in agrochemical use zones. [U4]

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    Kidney Stones—How to Get rid of them!

    R= Recipe

    If you have this condition then AVOID BEETS AND SPINACH AND ANY FOODS THAT WILL INCREASE OXALATE ACID AND OR URIC ACID—WHICH ARE THE BIGGEST CAUSE OF THISAsparagus-Parsley- Carrot—Spinach-Rhubarb-Chard-Beets-and Beet Leaves—Never mix with calcium or they will bind and cause the issue.are high in Oxalates

    RØMagnesium supplementation (400 – 600 mg per day) may inhibit Calcium Oxalate crystal formation in the Urine (Magnesium increases the solubility of Calcium Oxalate) and may thereby help to prevent Kidney Stones: –The Urine of Kidney Stones patients often has a reduced Magnesium:Calcium ratio.

    -Magnesium (combined with 100 mg Vitamin B6 per day) may cause partial elimination of Kidney Stones in 89% of Kidney Stones patients and total elimination in 79% of patients.-Magnesium supplementation may be very effective for preventing the reappearance of Kidney Stones in persons who have previously had Kidney Stones.

    Manganese may help to prevent Kidney Stones.

    Potassium may help to prevent Kidney Stones (by inhibiting the urinary excretion of Calcium).

    Selenium (combined with Vitamin E) may help to prevent Kidney Stones (by lowering elevated urinary excretion of Calcium and Oxalic Acid).

    Organic Acids

    RØCitric Acid may prevent recurrent Kidney Stones. –By consuming a good amount of citrus fruits will as well increase magnesium which will both balance out the kidneys and prevent or disperse kidney stones—-Another means would be to take citric acid powder and dissolve in water and add magnesium to it this will alleviate this —and as well some will take lemon juice and olive oil and mix 1 tablespoon of each in 2-3 oz of water and drink to assist with this and is also good for gall stones

    Inositol Hexaphosphate (Phytic Acid) may help to prevent and treat Kidney Stones.

    Phospholipids

    Phosphatidylcholine (PC) may prevent and dissolve Kidney Stones by emulsifying their constituent Lipids. Lecithin—Egg Yolk or Sunflower is preferred—utilizing this daily will as well increase phosphorus which will regulate the calcium and not allow it to build up

    Vitamins

    Vitamin B6 (10 – 100 mg per day) may prevent the formation of Kidney Stones caused by Hyperoxaluria (due to its role in the metabolism of Oxalic Acid).

    ØVitamin C may prevent the formation of Kidney Stones: -Kidney Stones do not normally develop as a result of consuming Vitamin C supplements. Human studies have shown that 10 grams per day of supplemental Vitamin C for long periods did not initiate or cause any Kidney Stones.

    Vitamin E (combined with Selenium) may help to prevent Kidney Stones (by lowering elevated urinary excretion of Calcium and Oxalic Acid).

    Water

    RØWater (when consumed in quantities sufficient to produce 2 – 3 quarts of Urine daily) may prevent the formation of Kidney Stones—if flushing with a distilled or RO water or Ionized water this will break up the calcium deposit and dilute the acid allowing the system to break and remove the excess

    These Foods/Herbs may Dissolve or Prevent Kidney Stones

    Algae

    Spirulina may help to prevent Kidney Stones and may help to prevent the damage to the Kidneys caused by Kidney Stones.

    Fruit- AS you can see either consuming a good dose of the citrus fruits or even juicing at home will eliminate or prevent stone formation

    Cranberry (juice) may help to prevent Kidney Stones.

    Grapefruit (juice) may help to prevent Kidney Stones (due to the Citric Acid content of Grapefruit). references

    Lemon (juice) may reduce the Pain of Kidney Stones and may facilitate their elimination.

    Orange (juice) may help to prevent Kidney Stones (due to the Citric Acid content of Oranges).

    Grains

    Barley Water may reduce the pain of Kidney Stones—making a barley milk or barley broth will increase the phosphorus which will regulate calcium in the kidney displacing the excess calcium—

    Herbs

    Blue Vervain may help to prevent and treat Kidney Stones. Buchu may help to treat Kidney Stones (according to folklore).

    RØBurdock may help to prevent and treat Kidney Stones.

    RØCollinsoni (Stoneroot) may accelerate the elimination of Kidney Stones. Cornsilk may break Kidney Stones up into fine grains which allows them to be eliminated (although it should be noted that Cornsilk has no effect on Oxalate Stones).

    Equisetum (Horsetail) is claimed to provide relief from the symptoms of Kidney Stones.

    Gravel Root is claimed to provide relief from the symptoms of Kidney Stones (according to anecdotal reports).

    Green Tea may help to prevent Calcium Oxalate Kidney Stones.

    Juniper Berries are claimed to provide relief from the symptoms of Kidney Stones (due to its Volatile Oil, Terpinen-4) (according to anecdotal reports).

    Parsley (juice diluted in Water) may facilitate the elimination of Kidney Stones. Phyllanthus (Phyllanthus niruri species) may help to prevent and treat Calcium Oxalate Kidney Stones.

    Seeds

    Pumpkin Seeds may reduce the incidence of Calcium Oxalate Stones.

    Vegetables

    RØParsnip may facilitate the elimination of existing Kidney Stones.-Juice this with parsely root or parsley and dandelion and will increase nutrient uptake and cleans the kidneys as well

    TOP G

    [U1]Other dietary Sources of DHA are Sea Algae and—

    (mg of DHA per 100 grams)

    Algae: Brown Algae Red Algae

    Eggs: Chicken Eggs 37 Omega Eggs 100

    Chicken Egg Yolk 114

    Fish Oils: Salmon Oil 18,200 Cod Liver Oil 11,000

    Sardine Oil 10,700 Menhaden Oil 8,560

    Herring Oil 4,210

    Meats: Brains – Lamb Ox 0.32

    Poultry: Chicken 40 Turkey 100

    Seafood: Cod 160 Haddock 126

    Halibut 250 Herring 1,080

    Eel * Salmon * 1,290

    Mackerel * 1,400 Trout *

    Sardines * Anchovy 911

    Caviar 3,800 Tuna 890

    Crab 361

    [U2]And this is just the tip of the iceberg here —this is what they know –this does not tell you what they do not know—this is a very elaborate way of wiping out and indigenious community without firing a bullet or wasting resources to eliminate a race or culture—and this is being done globally—MONSANTO = VATICAN—they Own Monsanto and started this company
    [U3]Seems Like Bio Warfare to me—
    [U4]I wonder who are the real terrorist here?religious zealots who you hear boo from or the silient but deadly chemical and agro megalith who bioterrorize indigenious people and take advantage of them who are not technologically at par—Makes you wonder eh!!
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    Show of the Week January 27 2012

     

    BASF pulls out of European GM market
    Liver and thyroid cancer rates rise
    Shocking and Disturbed White Coats over exaggerates and sensationalizes false alarm on vitamin industry

    Micronutrient combination may boost male fertility

    Fertility and what to do to increase it—If you want to!!

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    BASF has announced it will pull the plug on its European operations in
    genetically modified plant development due to a lack of acceptance in the market.[U1]
    The German chemical and biotechnology company said it would relocate the headquarters of its BASF Plant Science group from Limburgerhof in Germany, to Raleigh in the USA.[U2] The company added that it will be concentrating its plant biotechnology activities on its main markets in North and South America in the future[U3]. The company added that its development and commercialisation of all GM products targeted solely at cultivation in the European market will be halted – these include four varieties of potato and one of wheat. We are convinced that plant biotechnology is a key technology for the 21st century. However, there is still a lack of acceptance for this technology in many parts of Europe – from the majority of consumers, farmers and politicians, said Dr. Stefan Marcinowski, a member of the BASF board of executive directors, responsible for plant biotechnology. It does not make business sense to continue investing in products exclusively for cultivation in this market ,he said. We will therefore concentrate on the attractive markets for plant biotechnology in North and South America and the growth markets in Asia. Acceptance for innovation? BASF cited a lack of consumer and industry acceptance as the main reason for its decision to halt European operations in GM products. [U4]It added that the decision to relocate to the USA was taken because there is less resistance to the technology. The announcement was celebrated by environmental campaign groups Greenpeace and Friends of the Earth: This is another nail in the coffin for genetically modified foods in Europe, said Adrian Bebb of Friends of the Earth. Whilst Greenpeace EU agriculture policy director Marco Contiero said the announcement shows that BASF admits Europeans don’t want GM crops. Europeans are not alone in rejecting GM food,” he added. “BASF’s retreat to the Americas follows a string of defeats for the industry over the last two years in China, India, the Philippines, Thailand and elsewhere. Over 90% of GM food crops are grown in just four countries in the Americas–However, the move by BASF has also been also been seen a major blow for science and innovation in the European market.[U5] Professor Denis Murphy of the University of Glamorgan, UK, warned that Europe is now in danger of becoming a scientific backwater and will be unable to assist developing countries the address food insecurity [U6]There is now a danger that we will lose, not only companies like BASF, but also academic researchers and students – as well as any influence that we have had previously in developing countries where we used to be major providers of assistance and expertise argued Murphy – an expert in biotechnology. BASF said it will adjust the portfolio and site footprint of its plant science to reflect the move. The chemical giant said the move to new headquarters for activities in the area of plant biotechnology at Raleigh in North Carolina will see the current HQ site in Limburgerhof, Germany retain 11 positions in some functions, such as regulatory experts for Europe. The division employees 157 people in Limburgerhof, plus another 63 at facilities elsewhere in Europe. BASF said it would relocate 123 of those jobs[U7] to the North Carolina facility. The company plans to close its sites in Gatersleben, Germany, and in Svalöv, Sweden. The announcement will mean a reduction of 140 jobs in BASF’s European operations. The company said it aims to offer the affected employees other positions within the BASF wherever possible. Our employees have done excellent work over the past years. We regret that we are losing these high-quality jobs in Germany and Sweden said Marcinowski

    [U1]ABOUT &^%$# TIME!!! Now we need to get them out of Canada and the USA as well and while we are at it out of the planet

    [U2]This really really really really is a disappointment—in plain English Blows—Why Would Raleigh allow BASF a foothold in the USA to further Poison America and Canada??
    [U3]Not Sure this is Acceptable—Maybe we should boycott this—Send this to everyone in North America –I don’t want them in Canada—and I am sure a lot like myself are not wanting them here either or in the USA for that Matter–
    [U4]I hate to say this the Euorpeans are a lot smarter then we are—they are getting rid of there poison we are going to allow it here —I am so excited—
    [U5]What a crock –what this is really saying is Loss Profits to rape developing countries and poison them with noxious foods
    [U6]Food Security??? With GE or GMO’s!? now they will at the least see the benefit of there health cost go down—this is why the EU is being hit economically
    [U7]123 slaves to develop poisons to kill off people—lets call it what it is—BS
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    Liver and thyroid cancer rates rise
    A “relatively large” increase in the prevalence of liver cancer, which is nearly 100 times less common than prostate cancer, has been reported by Statistics Canada.—The agency released its report, Canadian Trends in Cancer Prevalence, on Tuesday, calling it the first such detailed report of the trends in the country.–The five-year prevalence rate for cancer overall rose 2.1 per cent a year between 1997 and 2008, according to Statistics Canada. Wong Maye/Associated Press-Prevalence rates for prostate cancer, the most common cancer in Canada, rose substantially, mainly because of the aging of the population over the study period 1997 to 2008, according to the report.[U8] Increases in the prevalence of breast cancer, the second most common cancer and the most common in women, were “more moderate.” Prevalence is defined as all cancers diagnosed within a given period among people alive on a specified date. In contrast, “incidence” refers to newly occurring cases. The five-year prevalence rate for cancer overall rose 2.1 per cent a year between 1997 and 2008.

    Liver cancer factors
    Larry Ellison and Kathryn Wilkins of the agency’s health statistics division said both the incidence and observed survival rose over the study period, with only about 20 per cent of the increase in prevalence due to aging of the population.–Various explanations for rising liver incidence have been suggested, they said, including:

    Increases in immigrants from countries where hepatitis B and C virus infections and exposure to aflatoxins that can lead to liver cancer are more common.
    Rising incidence of hepatitis C infection linked to intravenous drug use and sharing of needles.
    Growing rates of obesity and Type 2 diabetes.[U9]
    Liver cancer was the least prevalent cancer studied, with a five-year prevalence proportion of 6.2 cases per 100,000 persons on Jan. 1, 2008. For perspective, the corresponding figure for prostate cancer was nearly 100-fold higher at 610 cases per 100,000 men, Statistics Canada noted.–Many countries have also reported increases in thyroid cancer [U10]incidence rates, especially among young and middle-age women. Advances in diagnostic techniques are thought to be a factor, though a recent U.S. study suggested more detection alone can’t explain the increase in that country, the authors said.–Radiological tests such as ultrasound and CT are picking up smaller lumps in the thyroid that aren’t visible in clinical exams and some of turn out to be malignant, said Dr. Ali Imran, director of the thyroid oncology and neuropituitary clinics at Dalhousie University in Halifax.–“Others have suggested a higher radiation exposure but that wouldn’t explain why it is commoner in women,” he added in an email.

    Rates declined for cancers of the larynx and a type of uterine cancer.The biggest disparity between the sexes was for lung cancer. The five-year prevalence proportion fell slightly among men but rose among women — a difference that was attributed to sharper decreases in smoking prevalence among men since the mid-1960s[U11]

    Suggestions—To Maximize Liver and Thyroid health Utilize Lugols Iodine as well as Tyrosine and Selenium—and the Use of Taurine + Milkthistle or Milk thistle and Vitamin C—Mame Teas with Sage and Rosemary as well—and consume sea weeds and watercress-parsley and dandelion as well—this will target anticancer os so many different levels

    And Eliminate all Grains ( GMO) and other foods Like SOY and CANOLA ) Nothing packaged-boxed or bag with few exceptions

    ****************************************************************************

    Shocking and Disturbed White Coats over exaggerates and sensationalizes false
    alarm on vitamin industry

    The supplement trade must do more to combat the threat of spiking with unauthorized drugs or its critics
    will seize upon data unveiled on the Dr Oz show this week as further evidence that the industry is under-
    regulated,[U12] experts have warned. Dr Alex Schauss, chief executive of contract research organization
    AIBMR Life Sciences, was speaking following an investigation conducted by the Dr Oz show into spiking.
    Tests conducted by James Neal-Kababick, director of Oregon-based Flora Research Laboratories as part
    of the Dr Oz show investigation, revealed the presence of unauthorized active pharmaceutical ingredients
    (APIs), including some banned and potentially dangerous APIs, in supplements sold via multiple channels
    across the US. One supplement tested contained six times the levels of a drug banned by the FDA
    because of deaths associated with its use, while analysis of others revealed the presence of
    multiple banned APIs. Shocking and disturbing The findings were shocking and very disturbing and if
    continued will undermine consumer confidence unless effectively addressed,[U13] claimed
    Schauss, who has chaired the safety subcommittee of ComPLI (the Compliance and Label Integrity Committee
    of the Natural Products Association) since 1991. The levels of some of the APIs in these products was off the
    chart. But I think it also showed that this problem is not just limited to renegade supplement makers selling
    products on the internet, but to products sold all over the US in every kind of channel. [U14]Unfortunate
    lack of context However, it was unfortunate that a comment made by Neal-Kababick that nine out of 10 of his
    samples tested positive for APIs or their analogs was not clarified by Dr Oz, who left viewers with
    the erroneous impression that nine out of 10 supplements on the market were spiked with drugs,
    said Schauss. It was not made clear that the figures referred specifically to samples sent to Neal-Kababick’s lab
    because there were suspicions about them in the first place. It was also disappointing that comments
    made by another guest on the show – associate professor of medicine at Harvard University, Dr. Pieter Cohen –
    suggesting the solution was more regulation,[U15] were not challenged, said Schauss. He basically
    proposed a system where everything is tested before it is allowed to be put on the market. But
    that is not going to solve this problem. Anyone can send off a clean sample for testing – but is
    it the same product that you actually put on the market?[U16]” Laboratories with the expertise and
    experience to carry out forensic investigations Part of the problem was that rogue elements in the trade were
    getting ever more sophisticated at fooling those conducting analytical tests, said Schauss. There needs to be
    more help for people to know what methodologies they should be using to test for these substances and any
    analogs. He added: The information on what to test for and how is available and should be made available to
    stakeholders. It should be available to all QA/QC managers and directors. Manufacturers and distributors
    should be utilizing contract analytical laboratories that have the expertise and experience to carry out forensic
    investigations such as was performed for Dr Oz, if they don’t have the same quality of forensic capabilities.
    Meanwhile, retailers could also do more to demand from manufacturers and distributors selling them products
    to make sure this appropriate testing is done for any category of supplements where there is an economic
    incentive to mislead the public about a product’s content[U17], he said. Neal-Kababick, who recently alerted
    the trade to the I must say that I am seeing a rise in this problem not an abatement. Is that because more people
    are forwarding samples for us to test or is it because unethical midnight manufacturers are catching on to the
    opportunity? Regardless, we must remain vigilant, applying proper sampling plans and state of the art technology
    combined with strong phytoforensic techniques to assure that spiked raw materials do not make
    it into consume products[U18] Deliberate spiking or inadvertent contamination? Asked whether the APIs
    detected in samples passing through his labs were the result of deliberate spiking or inadvertent contamination
    due to poor supply chain controls, Neal-Kababick said: It’s both. We’re seeing more deliberate spiking with high
    levels of APIs but also more samples with low level Contamination. In the latter case, this might be due to
    manufacturers producing supplements in facilities that are also licensed to produce drugs, or where manufacturers
    are making counterfeit drugs and then producing ingredients or dietary supplements out of the same facility,
    he said. “Some of these companies use compressed air to clean up kit between batches – which can leave residues
    – instead of properly washing down the facility and then validating the cleaning as per pharmaceutical standard
    is sloppy manufacturing. He added: What is also worrying is that while most of the spiking is in weight loss, sports and
    male virility products, we’re also seeing more in anti-diabetic blood sugar support products – where we have
    detected anti-psychotic and blood pressure meds

    #344
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    Keymaster

    Micronutrient combination may boost male fertility

    A combination of eight micronutrients may boost sperm quality and enhance the chance of conception, suggests new
    data from Austria.A study with 132 sub-fertile males showed that three months of supplementation with the nutraceutical
    combination resulted in improvements in measures of sperm quality by up to 215%.–The micronutrient
    combination was also associated with higher rates of conception, with 34 pregnancies reported
    during the six months that followed the study, compared with 11 in the control group, according to
    findings published in the European e-Journal of Clinical Nutrition and Metabolism—The Austria-based
    researchers used the branded PROfertil supplement, containing L-carnitine, L-arginine, zinc, vitamin
    E, glutathione, selenium, coenzyme Q10 and folic acid, all of which are said to be required for
    “optimal sperm cell metabolism, DNA synthesis during spermatogenesis, proliferation and anti-oxidative
    protection. –In consideration of their biochemical function, these ingredients are of great significance for male
    reproduction wrote researchers led by Martin Imhof from the Fertility Clinic IMI in Vienna. Nutrients and
    fertility Sub-fertility in men is reported to account for between 25 and 30% of all infertility causes, and is
    listed as one of the many reasons that birth rates are falling in Western countries. [U19]In addition, about
    50% of male fertility is the result of unknown causes (idiopathic), said the Austria-based researchers, and
    nutrition has been touted as a potential way of boosting the quality of sperm. —[U20]The new study
    assessed the potential of a non-prescription nutraceutical containing eight micronutrients on sperm quality
    in 132 sub-fertile males with a mean age of 34, while 73 sub-fertile men with a mean age of 38 participated
    as controls.–The nutraceutical group received supplements providing total daily doses of 440 mg
    L-carnitine, 250 mg L-arginine, 40 mg zinc, 120 mg vitamin E, 80 mg glutathione, 60
    micrograms of selenium, 15 mg coenzyme Q10, and 800 micrograms of folic acid. The
    supplement was provided by Vienna-based Lenus Pharma GmbH. Results showed that men receiving
    the active supplement displayed a 33% improvement in ejaculatory volume, a 215% improvement
    in sperm cell density, and a 23% improvement in total sperm motility.[U21]These increments
    were significantly higher than those observed among controls, added Imhof and his co-workers. Limitations
    and potential We recognize the non randomized placebo controlled design of our study as a limitation said the
    researchers. However, a double blind, randomized, placebo-controlled study is currently on the way to support
    these preliminary results. Despite mentioned limitations and in light of the fact that therapies for sub-fertile men
    are still missing, the investigated compound is a promising therapeutic approach, improving sperm parameters
    and enabling natural conception for couples with idiopathic male infertility they concluded. Source: the European
    e-Journal of Clinical Nutrition and Metabolism Published online 3 December 2011, doi:10.1016/j.eclnm.2011.11.002
    Improvement of sperm quality after micronutrient SupplementationAuthors: M. Imhof, J. Lackner, M. Lipovac, P.
    Chedraui, C. Riedl
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    Fertility and what to do to increase it—If you want to!!

    Wheatgerm oil—has been utilized since the 1920’s to increase pregnancies in bot women and animals to increase births—it increase both the fertility of men and women –Apply 1-2 tablespoon daily

    Vitamin E from non soy sources—olive –rice-palm-wheat-almond oil—increases fertility in both men and women—400-800mgs a day or 1 tablespoon of the oils mentioned

    Acetly L Carnitine —2 grams a day increases Sperm Count

    Arginine -2-3 grams a day also increase sperm count as well for both genders increases Nitric oxide to the genital area

    Selenium- a must for the males—every load ejaculated releases the selenium to protect the seed as it travels—It protects the sac from cancer 200mcg 2 times a day

    Zinc –to sustain insulin and protect prostate 30 mgs 2 times a day

    Male Combo for the reproductive is Zinc 30 mgs Selenium 200 mcg and Vitamin E-400IU

    Fats are required for both genders to increase hormonal health and a healthy reproductive system

    Another Combination For Men and Women is

    B5-adrenal support-Choline –Connection support-and Arginine Heart Support—when combined they have a synergy to turn the switch on and can help sustain the the activities as well

    Consuming foods such as walnuts- peanuts-almonds-sunflower seeds-pumpkin seed will increase the Male reproductive system—

    Things to Avoid—Soy—Peas—Xenoestrogens-Canola-GMO Corn—Chemicals in general

     

    TOP H

    [U1]ABOUT &^%$# TIME!!! Now we need to get them out of Canada and the USA as well and while we are at it out of the planet

    [U2]This really really really really is a disappointment—in plain English Blows—Why Would Raleigh allow BASF a foothold in the USA to further Poison America and Canada??
    [U3]Not Sure this is Acceptable—Maybe we should boycott this—Send this to everyone in North America –I don’t want them in Canada—and I am sure a lot like myself are not wanting them here either or in the USA for that Matter–
    [U4]I hate to say this the Euorpeans are a lot smarter then we are—they are getting rid of there poison we are going to allow it here —I am so excited—
    [U5]What a crock –what this is really saying is Loss Profits to rape developing countries and poison them with noxious foods
    [U6]Food Security??? With GE or GMO’s!? now they will at the least see the benefit of there health cost go down—this is why the EU is being hit economically
    [U7]123 slaves to develop poisons to kill off people—lets call it what it is—BS
    [U8]Makes sense the Soy in the diet over a period of time has increased this type of cancer as well as Canola oil and other processes and not to mention the fact Canada is a leading developer of GMO foods which would contribute to this dilemma we all Face in Canada as well as other parts of the Planet
    [U9]None Of these Statistics would give these kind of number –None of them –this is a misdirecting of facts—on something of this scale it would have to be more to a common thread—foods Poisoning –and environmental exposure to solvent or chemicals or emf which would cause this
    [U10]Again this could be tied to Soy and Pesticide exposure—Not to mention Vaccinations which would in fact destroy both liver and thyroid
    [U11]Smoke and Mirrors–
    [U12]Under Regulated –or Over cautious—theDSHEA allows and provides all the regs that are needed—what is transpiring here is a retalitary effect from the FDA to use White Coats to force Peer pressure to change the 2 officials from gov’t
    [U13]ALLLLL HS!! This is about the FDA getting there fingers rapped—They had over stepped there power—and were told that they did not need more power –they had enough todo what was needed—this is about White Coats denying access to supplements
    [U14]OH OH we are now going to scare you into a lulled sense of security making you think that supplements are dangerious—OOOooOO the boogey man is going to get you Now!!! No ONE has ever Died from a vitamin –No One—Butttt People die from drugs and the number one killer is aspirin—and why are you not hearing this from so called campaigner for health??
    [U15]Regulation = Denied Access—and what they –the white coats working for the FDA want to do is Undermine your right to health by making you more dependent on Pharmaceuticals that shut down your brain—your spirit and your soul
    [U16]The FDA shut down it’s Labs years ago just like HPB in Canada did allowing the industry to test—this used to be a secondary line of defence—the problem was it was to easily corrupted by the very corporations handing in those samples so they bought out the branches of Gov’t and now conduct there own in house test—any one can fabricate anything—and todays vitamins by mainstream drug companies are the worse ones with the most additives and poisons
    [U17]Again this is such Rubbish and BS—the Health fod industry is more regulated then the Pharmaceutical industry HUGELY—and as has been reported No one has ever died from taking supplements—but many have died from pharmaceuticals and in fact a lot of them are poisonous and have all these analysis’s done and still people are getting rooked—-so the answer really is stop buy foreign raw materials and start getting raw materials locally—will never happen due to cost and money lost with hyper inflating things made at home
    [U18]Aren’t Pharmaseuticals Consumer Products??? And yet where is the outcry here!!—this is an elaborate art of persuasion to get people afraid of there supplements
    [U19]Birth rates are falling due to lack of semen from fluoride-soy-pesticides and xenoestrogens in everyday exposure and including biowarfare being done on the human race—with different waves of infection
    [U20]Shutting down the endocrine system and not feeding people what is required to sustain a health reproductive system would be more the case
    [U21]Arginine and acetyl L Carnitine is what they give guys who are porn stars to increase flow—it does work when trying to get pregnant add selenium with this —males lose there selenium when having intercourse due to the ejaculation so it is good to supplemet to protect the sac
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    Show of the Week Jan 30 2012

     

    The Bitter Truth About Splenda

    High Levels of MRSA Bacteria in U.S. Retail Meat Products, Study Suggests

    Environmental Exposure to Organochlorines May Impact Male Reproduction

    Pesticide Metabolites Associated With Increased Risk Of Testicular Cancers

    Nettle has protective activity of beta-cells of langerhans in hyperglycemic rats

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    The Bitter Truth About Splenda

    ‘If you were told to ingest a biologically alien synthetic chemical whose presence on this planet did not predate 1976, and whose structure is only a few atoms away from the deadly pesticide DDT, and you knew that not only were there no long term human safety studies performed on it, but that it had been already proven in tests to have following adverse health effects would you still consume it?’

    · Shrunken thymus glands (up to 40% shrinkage)

    · Enlarged liver and kidneys.

    · Abnormal histopathological changes in spleen and thymus

    · Increased cecal weight

    · Reduced growth rate

    · DNA Damage

    · Adverse changes to gastrointestinal bacteria

    · Abnormal Pelvic Mineralization

    · Decreased red blood cell count

    · Hyperplasia of the pelvis

    · Aborted pregnancy (Maternal & Fetal Toxicity)

    · Decreased fetal body weights and placental weights

    · Bowel inflammation

    · Triggering migraine

    · Increase glycosylation of hemoglobin (HbA1c) for diabetics

    ….would you still consume it? Of course not! And yet, millions of Americans (including our precious children!) are doing exactly that by consuming Splenda. So, what is sucralose, chemically speaking?

    Like “Splenda,” the term “sucralose” is a cute little marketing ploy. The true name of this ugly little chemical is actually too long for the human tongue to comfortably pronounce (which is usually an excellent indication that it is not safe to ingest!) Go ahead and see if you can wrap your vocal chords around this phonetic monstrosity:
    1,6-dichloro-1,6-dideoxy-BETA-D-fructofuranosyl-4-chloro-4-deoxy-alpha-D-galactopyranoside

    Despite the intended insinuation, sucralose is not a form of sucrose (cane sugar). Sucralose/Splenda is produced through artificially substituting three hydroxyl groups (hydrogen + oxygen) with three chlorine atoms in the sugar (sucrose) molecule. Natural sugar is a hydrocarbon built around 12 carbon atoms.

    When transformed into Splenda it becomes a chlorocarbon, in the same family as deadly pesticides like DDT, insecticides, biocides, disinfectants like Chlorox Bleach, and WWI poison gas like dichlorourea.

    The makers of sucralose/Splenda argue that this “remarkably stable” chemical passes unchanged into the urine and feces, when in fact, up to 11% to 27% is absorbed into the body (FDA, 1999). In fact, the varying degrees to which sucralose is absorbed is used as a marker for gut and intestinal permeability to determine certain disease states. Once absorbed, some portion of this chlorocarbon accumulates in the body (between 1.6% to 12.2%). What effects will these accumulated chemicals have?

    According to James Bowen, M.D:

    “Any chlorocarbons not directly excreted from the body intact can cause immense damage to the processes of human metabolism and, eventually, our internal organs. The liver is a detoxification organ which deals with ingested poisons. Chlorocarbons damage the hepatocytes, the liver’s metabolic cells, and destroy them. In test animals Splenda produced swollen livers, as do all chlorocarbon poisons, and also calcified the kidneys of test animals in toxicity studies.”

    How can this be true for an FDA approved sweetener?

    FDA approval does not in any way guarantee safety…..sadly enough, in many cases, it guarantees the exact opposite. Take aspartame for instance. Aspartame (Equal/NutraSweet) contains 10% methanol, which is broken down in our body into two extremely toxic substances: formaldehyde and formic acid. There are over 30 known adverse health effects associated with its consumption! This sweetener gained FDA approval in 1981, despite appalling evidence linking it to cancer, particularly, brain cancer.

    So, if Splenda is not a viable alternative to sugar, what can we use instead?

    When one uncouples the experience of “sweetness” from caloric content, the body becomes confused because it does not receive nourishment and therefore will not attain satiety – this, in turn, leads to overindulgence. Indeed, new studies have shown exactly this: those who consume synthetic sweeteners are more prone to obesity. What this means is that when we ingest something sweet, it should also have caloric and nutritional content. Anything less than this equation is a recipe for failure and ill health.

    Thankfully Nature provides us with a veritable cornucopia of healthy sweeteners: honey, stevia, xylitol, erythritol , maple syrup or sugar, coconut nectar or sweetner , malitol, and birch tree syrup all of which are available at a local health food store or ethnic market. Next time that sweet tooth calls, remember not to succumb to advertising hype which would convert poisonous chemicals into “magical” no-calorie sweeteners. Use both common sense and a sense of moderation, and your body will thank you.

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    High Levels of MRSA Bacteria in U.S. Retail Meat Products, Study Suggests

    ScienceDaily (Jan. 20, 2012) — Retail pork products in the U.S. have a [U1]higher prevalence of methicillin-resistant Staphylococcus aureus bacteria (MRSA) than previously identified, according to new research by the University of Iowa College of Public Health and the Institute for Agriculture and Trade Policy.–MRSA can occur in the environment and in raw meat products, and is estimated to cause around 185,000 cases of food poisoning each year. The bacteria can also cause serious, life-threatening infections of the bloodstream, skin, lungs and other organs. MRSA is resistant to a number of antibiotics.—The study, published Jan. 19 in the online science journal PLoS ONE, represents the largest sampling of raw meat products for MRSA contamination to date in the U.S. The researchers collected 395 raw pork samples from 36 stores in Iowa, Minnesota and New Jersey. Of these samples, 26 — or about 7 percent — carried MRSA.—“This study shows that the meat we buy in our grocery stores has a higher prevalence of staph than we originally thought,” says lead study author Tara Smith, Ph.D., interim director of the UI Center for Emerging and Infectious Diseases and assistant professor of epidemiology. “With this knowledge, we can start to recommend safer ways to handle raw meat products to make it safer for the consumer.”

    The study also found no significant difference in MRSA contamination between conventional pork products and those raised without antibiotics or antibiotic growth promotants.

    “We were surprised to see no significant difference in antibiotic-free and conventionally produced pork,[U2]” Smith says. “Though it’s possible that this finding has more to do with the handling of the raw meat at the plant than the way the animals were raised, it’s certainly worth exploring further.”–Story Source-The above story is reprinted from materials provided by University of Iowa, via Newswise. –Journal Reference-Ashley M. O’Brien, Blake M. Hanson, Sarah A. Farina, James Y. Wu, Jacob E. Simmering, Shylo E. Wardyn, Brett M. Forshey, Marie E. Kulick, David B. Wallinga, Tara C. Smith. MRSA in Conventional and Alternative Retail Pork Products. PLoS ONE, 2012; 7 (1): e30092 DOI: 10.1371/journal.pone.0030092

     

    Food Statistics > Pork consumption per capita (most recent) by country

    Showing latest available data.

    Rank

    Countries

    Amount

    # 1

    Denmark:

    142.6

     

    # 2

    Spain:

    123

     

    # 3

    Hong Kong:

    121.9

     

    # 4

    Germany:

    117

     

    # 5

    Hungary:

    90.2

     

    # 6

    Poland:

    83.2

     

    # 7

    Sweden:

    79.4

     

    # 8

    France:

    76.6

     

    # 9

    China:

    75

     

    # 10

    Singapore:

    69.1

     

    # 11

    Canada:

    66.2

     

    # 12

    United States:

    62.8

     

    # 13

    United Kingdom:

    54.3

     

    # 14

    Australia:

    40

     

    # 15

    Japan:

    36.1

     

    # 16

    Russia:

    29

     

    # 17

    Mexico:

    22.4

     

    # 18

    Brazil:

    20.2

     

     

    Total:

    1,309

     

     

    Weighted average:

    72.7

     

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    Environmental Exposure to Organochlorines May Impact Male Reproduction

    ScienceDaily (Jan. 9, 2012) — Melissa Perry, Sc.D., M.H.S., professor and chair of the Department of Environmental and Occupational Health at the GW School of Public Health and Health Services and adjunct associate professor at the Harvard School of Public Health, led an observational study indicating that environmental exposure to organochlorine chemicals, including Polychlorinated Biphenyls (PCBs) and p,p’-DDE (the main metabolite of the insecticide DDT) can affect male reproduction.–The research was published online on Dec. 21, 2011 in the journal Environmental Health Perspectives. —The researchers studied 192 men who were part of couples that were sub-fertile, to see if the men with higher levels of organochlorines in their blood showed evidence of increased rates of sperm abnormalities. They looked for sperm disomy, which occurs when sperm cells have an abnormal number of chromosomes. While all men have a certain number of sperm with such abnormalities, researchers found that men with higher levels of DDE and PCBs had significantly higher rates of sperm abnormalities.–“This research adds to the already existing body of evidence suggesting that environmental exposure to certain chemicals can affect male fertility and reproduction. We need to further understand the mechanisms through which these chemicals impact sperm,” said Dr. Perry. “While we cannot avoid chemicals that already persist in the environment, it is imperative that decisions about putting biologically active chemicals into the environment need to be made very carefully, because there can be unanticipated consequences down the road.”-The researchers used a new sperm imaging methodology developed by Dr. Perry and colleagues to detect the chromosomal abnormalities, which allowed them to study a larger sampling of individuals than previous studies.–Story Source-The above story is reprinted from materials provided by George Washington University Medical Center.

    ***********************************************************************

    Pesticide Metabolites Associated With Increased Risk Of Testicular Cancers

    ScienceDaily (Apr. 29, 2008) — Men exposed to organochlorine pesticide metabolites, such as DDE, had an increased risk of testicular germ cell tumors. Previous research suggested that persistent exposure to organochlorine pesticides may increase the risk for some types of testicular cancer, but that observation had not been replicated in an independent data set.—In the current case-control study, Katherine McGlynn, Ph.D., of the National Cancer Institute in Bethesda, Md., and colleagues measured the amount of pesticides or their metabolic breakdown products in blood samples from men who were later diagnosed with testicular germ cell tumors and in blood samples from healthy controls. The men were all part of the U.S. Servicemen’s Testicular Tumor Environmental and Endocrine Determinants study. The 915 control subjects and 739 case subjects had donated blood samples an average of 14.2 years prior to the current analysis.–When the researchers divided the participants into quartiles based on the concentration of a particular pesticide in their blood, the team saw a trend for an increased risk of testicular cancer in men with higher concentrations. The trend reached statistical significance for some of the pesticides and metabolites tested. For example, men in the highest quartile for DDE (p,p’-dichlorodiphenyldichloroethylene)–which is a persistent metabolite of DDT (p,p’-dichlorodiphenyltrichloroethane)–were 1.7 times more likely to develop testicular germ cell tumors than those with the lowest concentration.—“If the relative risks calculated in this study are accurate, the population-attributable risk of DDE (i.e., the propor¬tion of disease in the study population that is attributable to DDE exposure) would be approximately 15 percent for all [testicular germ cell tumors],” the authors write.–This research was reported April 29 in the Journal of the National Cancer –Story Source-The above story is reprinted from materials provided by Journal of the National Cancer Institute, via EurekAlert!, a service of AAAS.

    ****************************************************************************

    Nettle has protective activity of beta-cells of langerhans in hyperglycemic rats.The protective activity of Urtica dioica leaves on blood glucose concentration and beta-cells in streptozotocin-diabetic rats.

    Pak J Biol Sci. 2007 Apr 15;10(8):1200-4

    Authors: Golalipour MJ, Khori V

    This study was done to determine the protective activity of the hydroalcholic extract of Urtica dioica leaves on Hyperglycemia and beta-cells in hyperglycemic rats. Thirty Wistar rats were allocated in groups of normal, Diabetic and treatment. Hyperglycemia in Rats induced by 80 mg kg(-1) streptozotocin. In treatment group, animals received hydroalcholic extract of Urtica dioica 100 mg kg(-1) day(-1) for five days, intraperitoneally and then hyperglycemia induced by streptozotocin. The blood glucose concentration was measured by using a Glucometer in 1st, 3rd and 5th weeks. In the end of 5th weeks the animals in each group were sacrificed by anesthesia and whole pancreas in three groups extracted and fixed in bouin’s fluid and stained by chromealum hematoxiline-phloxine and beta cells were counted in three groups by Olympus microscope. Mean +/- SE of blood glucose concentrations in the end of fifth weeks were 99.4 +/-5.0, 454.7 +/- 34.5 and 303.6 +/- 100.6 in control, diabetic and treatment groups, respectively (p < 0.05). The percentages of beta-cells in control, diabetic and treatment groups were 73.6, 1.9 and 22.9%, respectively. The percentage of beta-cells in treatment group comparing with diabetic group was significant (p < 0.05). This study showed that the protective administration of hydroalcholic extract of Urtica dioica has hypoglycemic effect and protective activity of beta-cells of langerhans in hyperglycemic rats.—PMID: 19069917 [PubMed – indexed for MEDLINE]

    Recipe –add Nettle to a blender and distilled water to it and alcohol—measure this so that the water will be 50/50 with the alcohol—and add to blender and then add the nettle 1/3 rd the amount to the water/alcohol mix—blend this at high speed for about 10 minutes and strain —you will have made an extract—use a half a tsp as needed

    Another means to do this is to add nettle with cinnamon bark and juniper berry—place all 3 components in a coffee percolator and then seal the containment area—and add distilled water to the pot—fill it to the mark and then allow it to perk on the stove for about 10 minutes or allow it to get about 1-2 inches from the bottom—pour out to a bottle and when it cools add alcohol to it 2:1 to the extract—use ½ tsp several times a day

    These recipes have other uses as well not just for diabetic conditions but for a host of others as well ranging from anti bacterial-antifungal-antiviral-male issues-anti cancer issues-anti microbial issues-blood-organ –immune –antioxidant-and many more –something that can be gotten from the woods or from any open field –if gotten from out doors make sure you clean these with some kind of cleaning method to remove potential chemtrail and GMO fall out

    TOP I

    [U1]This whole report should have everyone alarmed and cautious about where and what meat they buy—this would include kosher and Hal el as well –if the meat can get contaminated with MRSA which is something coming out of the medical field or clinical or pharmaceutical setting thennnnn we have a problem with somebody doing this purposely—they are trying to get us all to be livestock grazing on veges—the largest consumers of this tpe of foods are –Asians—are we in Biowarfare?

    Something to think about
    [U2]In other words the so called natural meats in a health food store may not have any significance

    #345
    Avatarwebmaster
    Keymaster

    Home Made Protein Shakes—will give some ideas to make a good protein shake ( meal ) take 30 grams ( or one scoop of a container for protein ) of gelaton— and add to 2 cups of water in a pot and boil and when water is boiling add the gelaton—in the blender add 3-4 eggs ( whole eggs with no shells) 1 tsp of oil or a slice of butter—add herbs or condiments of choice to this ( garlic and onion powders—sea salt—tumeric—pepper –paprika) once the gelaton is dissolved then get the blender going with the eggs –leave the lid on top and open center of lid where you can pour into the blender while blending—once the pot is emptied then allow for blending for about 2-4 minutes—when done you will have cooked the egg in that solution and it will have blended—you have now a protein shake with the equivalency of 45 grams of protein—

     

    ØTake ¼ container of cottage cheese add to blender –add water 1 ½ cup – 2cup-add berries or fruit—add 1 tablespoon of oil of your choice—and add gelaton 15 grams—blend for 3 minutes—you have 40 grams of protein

     

    ØTake yogurt ( Balkan Style original) and take half the container and add 1 multiple vitamin complete with B’s and other nutrients add 2 capsules—add fat ( of choice) and add water 2 cups—and add cocoa and 1 scoop of dried egg protein—blend together for 3 minutes—when done you have made a meal replacement with a complete meal 30 grams of protein

     

    ØIn the Morning consume 3 eggs and 2 oz of yogurt and add fat to either the eggs or yogurt—-have some fruit like apples or berries or citrus—have a tea—this will give you 20 grams of protein

     

    So you can see how it is easy to get your daily requirement of protein—

     

    ØDuring the day consume a adequate amount of protein from nut –animal –dairy sources –and always ad fat with the protein

    #346
    Avatarwebmaster
    Keymaster

    Fatty liver Resolutions

     

    Betaine may help to prevent and reverse Fatty Liver.

     

    Amino Acids

     

    Cysteine may help to prevent Alcohol-induced Fatty Liver:

     

    N-Acetyl-Cysteine (NAC) may help to prevent Alcohol-induced Fatty Liver. references

     

    S-Adenosylmethionine (SAMe) may help to prevent and treat Fatty Liver. references

    Taurine may help to prevent Alcohol-induced Fatty Liver.

     

    Carbohydrates

     

    Chondroitin Sulfate may counteract the ability of high consumption of Dietary Fats to cause Fatty Liver.

     

    Lipids

     

    Gamma-Linolenic Acid (GLA) may help to prevent Alcohol-induced Fatty Liver. references

    Phosphatidylcholine may help to prevent and treat Fatty Liver.

     

    Peptides

     

    Carnitine may alleviate and prevent Fatty Liver – some evidence suggests that Carnitine deficiency within the Liver may be the underlying cause of Fatty Liver.

     

    Polyphenols

     

    Cynarin may inhibit the ability of Alcohol (ethanol) to cause Fatty Liver. references

    Silymarin may alleviate Fatty Liver.

     

    Vitamins

     

    Fatty Liver may occur as a result of Choline deficiency.

    Folic Acid may help to prevent (Alcohol-Related) Fatty Liver.

    Inositol may help to prevent Fatty Liver. references

    The Pantethine form of Vitamin B5 (600 mg per day) may cause the total disappearance of some cases of Fatty Liver.

     

    Vitamin B12 may help to prevent Fatty Liver.

    Vitamin C (when consumed prior to or during Alcohol consumption) may inhibit the ability of Alcohol to cause Fatty Liver.

    Vitamin E (when consumed prior to or during Alcohol consumption) may inhibit the ability of Alcohol to cause Fatty Liver.

    **************************************************************************

    Recipe for NAFLD—

    Using beets and apple as a sauce—take 2 apples peeled and 1 beet chopped and add to a blender and add ¼ cup of water and blend til it is sauced –stop the blender and add to a glass container and utilized 2-3 oz 3 times a day to increase the betaine levels

     

    Utilizing HCL supplements with pepsin taking them orally with every meal

     

    Taurine Supplements will increase Bile salts that will break down the fatty build up in the liver

     

    Sunflower Lecithin or Egg Yolk Lecithin—will remove the excessive fat build up

     

    Lipase- will break down the fats in the diet will make it easier on the liver and pancreas

     

    Using B5 daily will lower the fatty build up as well

     

    ************************************************************************

    Food police reject preschooler’s homemade lunch… in favour of chicken nuggets
    By Meghan Keneally–15th February 2012

    A preschool girl was told her homemade meal wasn’t healthy enough – so a school cafeteria monitor made her eat chicken nuggets instead.–The rejected meal consisted of a turkey and cheese sandwich on whole wheat bread, with a side of a banana, potato chips, and apple juice.–“What got me so mad is, number one, don’t tell my kid I’m not packing her lunch box properly” , the mother from North Carolina, who wished to remain anonymous, told a local newspaper.–Homemade goodness: A 4-year-old girl was told that her turkey and cheese sandwich was unhealthy and a school monitor made her buy a lunch–Alternative: The school-made lunch included chicken nuggets instead–‘I pack her lunchbox according to what she eats. It always consists of a fruit. It never consists of a vegetable. She eats vegetables at home because I have to watch her because she doesn’t really care for vegetables.’–The Department of Health and Human Services requires students to eat lunches that consist of meat, milk, grain, and two servings of fruit or vegetables.–It isn’t clear what the entire meal that the cafeteria at West Hoke Elementary School consisted of, but all that the picky four-year-old girl ate were the chicken nuggets.–The mother still wonders what it was exactly that disqualified her meal, and she expects that the bag of potato chips were potentially the problem.–That said, Jani Kozlowski, the spokesperson from the DHHS children’s division said that the meal sounds like it would have passed the federal guidelines test.–‘With a turkey sandwich, that covers your protein, your grain, and if it had cheese on it, that’s the dairy,’ Ms Kozlowski told The Carolina Journal.–‘It sounds like the lunch itself would’ve met all of the standards,’ she said, not having worked with the school in question herself.–On top of the wasted food that was sent home with the little girl at the end of the day was a $1.25 bill for the ‘healthy’ school lunch.-‘I don’t feel that I should pay for a cafeteria lunch when I provide lunch for her from home,’ the mother wrote in a letter to her state representative.

    http://www.dailymail.co.uk/news/article-2101354/Food-police-reject-preschoolers-homemade-lunch–favour-chicken-nuggets.html#ixzz1mgu7JFmU

     

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    Myths and Truths About Fiber

    [1]For decades, fiber has been touted as an essential component of a healthy diet. The supposed benefits of a high-fiber diet have been drilled into us through recommendations by our doctors, government, and the food industry alike, yet many of these health claims have not been proven by research.—In fact, many studies have demonstrated that excess intake of fiber may actually be harmful, particularly for gut health.–The majority of the research supporting the benefits of dietary fiber come from epidemiological studies that link the consumption of fiber-rich fruits and vegetables with a lowered risk of certain diseases such as obesity, heart disease and cancer, particularly colon cancer. (1 [2]) Yet when tested in the lab, controlled intervention trials that simply add fiber supplements to an otherwise consistent diet have not shown these protective effects. (2 [3]) (3 [4]) (4 [5])–The Institute of Medicine recommends a daily fiber intake of 38 grams for men and 25 grams for women (5 [6]), which may come from dietary fibers, both soluble or insoluble, or the addition of “functional fibers” to the diet. The IOM defines functional fibers as non-digestible carbohydrates that have been isolated or extracted from a natural plant or animal source, or they may be manufactured or synthesized. Examples of functional fibers are psyllium husks, chitin from crustacean shells, fructooligosaccharides, polydextrose, and resistant dextrins. (6 [7])—These functional fibers are often added to processed foods as a way to bulk up the fiber content for consumers looking to meet the IOM intake guidelines. A recent report by NPR commented that despite the lack of significant evidence linking fiber intake to health outcomes such as reduced heart disease or cancer, many consumers are buying foods that are fortified with synthetic fiber additives under the guise of health promotion. (7 [8]) Three grams of added fiber is enough to allow these food products to claim to be a good source of fiber, and the food industry has used these fiber guidelines as a way to increase their sales of grain-based products in particular. (8 [9])-Tan and Seow-Choen, in their 2007 editorial on fiber and colorectal disease, call insoluble fiber “the ultimate junk food”, as “it is neither digestible nor absorbable and therefore devoid of nutrition.” (9 [10]) Excess insoluble fiber can bind to minerals such as zinc, magnesium, calcium, and iron, preventing the absorption of these vital nutrients. (10 [11]) Large excesses of certain soluble fibers like pectin and guar may also inhibit pancreatic enzyme activity and protein digestion in the gut, leading to an anti-nutritive effect. (11 [10])– The addition of insoluble and soluble fibers to processed foods may actually cause these foods to be even less nutritious than if they were not enriched with any fiber at all.–A high-fiber diet has also been described as a preventative strategy for the development of diverticulosis, a disease that is markedly more common in Western countries. However, when researchers tested the theory that a high-fiber diet prevented diverticulosis, they not only found that a high intake of fiber did not reduce the prevalence of diverticulosis, but that a high-fiber diet and greater number of bowel movements were independently associated with a higher prevalence of diverticula. (12 [12]) Interestingly, this study found no association between the presence of diverticulosis and red meat intake, fat intake, or physical activity, which are other factors commonly attributed to diverticulosis.–The researchers hypothesized that one possible effect of a high-fiber diet in the development of diverticulosis could be the quantitative and qualitative changes in gut bacteria due to the excessive fiber intake. Both insoluble and soluble fibers are shown to alter gut bacteria in as little as two weeks. (13 [13]) It is possible that the high levels of excess fiber and overgrowth of intestinal bacteria may have contributed to the development of diverticular pouches in the colon.-This hypothesis brings up another side to the fiber debate: the effect of dietary fiber on beneficial gut bacteria, as well as the bacterial fermentation of undigested soluble fiber into short-chain fatty acids such as butyrate. When we eat the soluble fibers found in whole plant foods, the bacteria in our gut ferment these fibers into short-chain fatty acids like butyrate, proprionate, and acetate, and greater amounts of fiber consumed will lead to greater short-chain fatty acid production. (14 [14]) In this case, naturally occurring soluble fibers are very important for feeding the friendly bacteria that live in our guts.[U1]–One of the risks of long term very low-carbohydrate (VLC) diets, in my view, is the potentially harmful effect they can have on beneficial gut flora. VLC diets starve both bad and good gut bacteria, which means these diets can have therapeutic effects on gut infections in the short term, but may actually contribute to insufficiency of beneficial strains of gut bacteria over the long term. Providing adequate levels of carbohydrate and soluble fiber to feed friendly bacteria is important for optimizing digestive health and maintaining the integrity of the gut lining through the production of short-chain fatty acids.–Stephan Guyenet has written an excellent blog post describing the benefits of butyrate and other short-chain fatty acids on the maintenance of healthy gut integrity. (15 [15]) Butyrate has anti-inflammatory effects, increases insulin sensitivity, and may delay the development of neurodegenerative diseases. It may also be helpful in the treatment of diseases of the colon such as Crohn’s, IBS or ulcerative colitis. (16 [16])—Stephan believes that butyrate may play a significant role in healthy metabolic function, stress resistance, and the immune response. He also asserts that the epidemiologically observed benefits of a diet high in naturally occurring fiber are likely due to the higher butyrate production from these diets. In this case, a higher fiber diet could be protective and beneficial for health, particularly if the fiber is soluble.

    So what does this mean for our own consumption of fiber?
    Ideally, dietary fiber should be coming from whole food plant sources. Many foods in the Paleo diet are great sources of both soluble and insoluble fiber, such as yams and sweet potatoes, green leafy vegetables, carrots and other root vegetables, fruits with an edible peel (like apples and pears), berries, seeds, and nuts. Interestingly, butyrate itself is also found in high-fat dairy products such as butter and cheese, and can also be provided by the bacteria found in fermented foods. (17 [17])—-Although I recommend that most people get fiber from whole foods, there are some people that may benefit from soluble fiber supplementation – including those that aren’t able to eat fruit or starch due to blood sugar issues or weight regulation, and those with severely compromised gut flora or gut dysbiosis. In these cases I’ve found soluble fiber and/or prebiotic supplements to be helpful.—For healthy people, including a variety of fibrous whole plant foods, fermented foods, and high-fat dairy as tolerated should eliminate the need to supplement with extra fiber, especially those insoluble fibers that are from sources high in anti-nutrients. A Paleo diet with some level of attention paid to the quality and quantity of vegetables, fruits, and starchy tubers can provide adequate levels of soluble fiber to feed the friendly bacteria in the gut that convert these fibers into beneficial short-chain fats like butyrate.

    Recommended supplements if needed:

    Prebiotic: Klaire Labs Biotagen [18]

    Soluble fiber: Organic Acacia Fiber [19]

    Caution: it’s crucial to start with a very low dose of prebiotic or soluble fiber and build up slowly over time. This will minimize any potential adverse reaction that can occur with significant changes (even positive changes) to the gut microbiome. For Biotagen, start with 1/4 of 1/8 of a tsp (1/32 tsp.) and increase by 1/32 of a tsp every 4-5 days. For Organic Acacia Fiber, start with 1/4 of a tsp. once per day and build slowly from there.

    [1] Image: http://chriskresser.com/wp-content/uploads/all-bran.jpg

     

    [2] 1: http://www.ncbi.nlm.nih.gov/pubmed/19335713

     

    [3] 2: http://www.ncbi.nlm.nih.gov/pubmed/10770980

     

    [4] 3: http://jn.nutrition.org.libproxy.lib.unc.edu/content/133/10/3141.full

     

    [5] 4: http://www.ncbi.nlm.nih.gov/pubmed/12223437

     

    [6] 5: http://www.iom.edu/~/media/Files/Activity%20Files/Nutrition/DRIs/DRI_Macronutrients.pdf

     

    [7] 6: http://lpi.oregonstate.edu/infocenter/phytochemicals/fiber

     

    [8] 7: http://www.npr.org/blogs/thesalt/2012/02/13/146706553/is-adding-fiber-to-food-really-good-for-your-health

     

    [9] 8: http://www.cnpp.usda.gov/Publications/FoodSupply/FiberFactSheet.pdf

     

    [10] 9: http://www.wjgnet.com/1007-9327/13/4161.pdf

     

    [11] 10: http://www.tandfonline.com/doi/abs/10.1080/10408399109527539

     

    [12] 12: http://www.gastrojournal.org/article/S0016-5085(11)01509-5/abstract

     

    [13] 13: http://www.sciencedirect.com/science/article/pii/S0271531705802167

     

    [14] 14: http://chriskresser.comwww.ajcn.org/cgi/reprint/33/4/754.pdf

     

    [15] 15: http://wholehealthsource.blogspot.com/2009/12/butyric-acid-ancient-controller-of.html

     

    [16] 16: http://www.ncbi.nlm.nih.gov/pubmed/16633129

     

    [17] 17: http://huntgatherlove.com/content/human-colon-evolution-part-4-secrets-butyrate

     

    [18] Klaire Labs Biotagen: http://www.amazon.com/gp/product/B001PYXMTQ/ref=as_li_ss_tl?ie=UTF8&tag=chrikres-20&linkCode=as2&camp=1789&creative=390957&creativeASIN=B001PYXMTQ

    [19] Organic Acacia Fiber: http://www.amazon.com/gp/product/B0002ON8DU/ref=as_li_ss_tl?ie=UTF8&tag=chrikres-

    20&linkCode=as2&camp=1789&creative=390957&creativeASIN=B0002ON8DU

     

    **************************************************************************

    Butyrate—what it does

     

    Sources of Butyrate—

    Butter: 3,230 Parmesan Cheese 1,510

    Swiss Cheese 1,100 Cream 1,080

    Cheddar Cheese 1,050 Gruyere Cheese 1,050

    Edam Cheese 1,000 Gouda Cheese 1,000

    Cream Cheese 1,000 Feta Cheese 775

    Blue Cheese 658 Milk 75

     

    Butyric Acid may Enhance the Function of these Substances

     

    Microorganisms-Butyric Acid functions as a nutrient for the Beneficial Bacteria within the Digestive Tract.

     

    Minerals-Butyric Acid may facilitate the absorption of Calcium in the Colon.

    Butyric Acid may facilitate the absorption of Magnesium in the Colon.

     

    These Substances may Enhance the Function of Butyric Acid

     

    Carbohydrates—Dietary Carbohydrates (especially Polysaccharides) are fermented (by Beneficial Bacteria) within the Large Intestine resulting in the manufacture of Butyric Acid–Inulin may enhance the production of Butyric Acid in the Colon.

    Of all Carbohydrates, Starch produces the greatest concentration of Butyric Acid:

    The constituent of Starch that most contributes to the production of Butyric Acid is Amylose that escapes digestion (i.e. Resistant Starch).

    Fructooligosaccharides (FOS) (by nourishing Beneficial Bacteria in the Intestines which produce Butyric Acid) may facilitate the endogenous production of Butyric Acid in the digestive tract.

    Larch Arabinogalactan may stimulate the body’s production of Butyric Acid.

     

    Lipids—Acetic Acid may enhance the ability of Butyric Acid to stimulate the absorption of Calcium and Magnesium in the Colon.

     

    Microorganisms–Beneficial Bacteria within the Large Intestine (especially the Colon) are responsible for the fermentation of dietary Carbohydrates that result in the production of Butyric Acid.

     

    Pharmaceutical Drugs–Aspirin may enhances the ability of Butyric Acid to prevent Colon Cancer.

     

    Resveratrol may enhance the ability of Butyric Acid to prevent Colon Cancer.

     

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    Betaine

     

    Betaine may help to prevent and reverse Fatty Liver. references

     

    Amino Acids

     

    Cysteine may help to prevent Alcohol-induced Fatty Liver: references

     

    N-Acetyl-Cysteine (NAC) may help to prevent Alcohol-induced Fatty Liver. references

     

    S-Adenosylmethionine (SAMe) may help to prevent and treat Fatty Liver. references

    Taurine may help to prevent Alcohol-induced Fatty Liver. references

     

    Carbohydrates

     

    Chondroitin Sulfate may counteract the ability of high consumption of Dietary Fats to cause Fatty Liver. references

     

    Lipids

     

    Gamma-Linolenic Acid (GLA) may help to prevent Alcohol-induced Fatty Liver. references

    Phosphatidylcholine may help to prevent and treat Fatty Liver. references

     

    Peptides

     

    Carnitine may alleviate and prevent Fatty Liver – some evidence suggests that Carnitine deficiency within the Liver may be the underlying cause of Fatty Liver. references

     

    Polyphenols

     

    Cynarin may inhibit the ability of Alcohol (ethanol) to cause Fatty Liver. references

    Silymarin may alleviate Fatty Liver. references

     

    Vitamins

     

    Fatty Liver may occur as a result of Choline deficiency. references

    Folic Acid may help to prevent (Alcohol-Related) Fatty Liver. references

    Inositol may help to prevent Fatty Liver. references

    The Pantethine form of Vitamin B5 (600 mg per day) may cause the total disappearance of some cases of Fatty Liver.

     

    Vitamin B12 may help to prevent Fatty Liver. references

    Vitamin C (when consumed prior to or during Alcohol consumption) may inhibit the ability of Alcohol to cause Fatty Liver.

    Vitamin E (when consumed prior to or during Alcohol consumption) may inhibit the ability of Alcohol to cause Fatty Liver.

     

    Betaine-2

     

    Betaine (especially the Trimethylglycine (TMG) form of Betaine) may help to prevent Cardiovascular Diseases (due to Betaine functioning as a methyl donor which lowers Homocysteine levels).

     

    Digestive System

     

    Betaine Hydrochloride may reduce the risk of Gallstones in persons with low levels of Hydrochloric Acid (i.e. in persons afflicted with Hypochlorhydria).

    Betaine Hydrochloride may alleviate many cases of Heartburn (by increasing the level of Hydrochloric Acid in the Stomach).

     

    Betaine Hydrochloride functions as a supplemental source of Hydrochloric Acid for Hypochlorhydria patients.

    Betaine Hydrochloride may be useful for the treatment of Small Intestinal Bacterial Overgrowth Syndrome (Hypochlorhydria (lack of Hydrochloric Acid) patients have increased risk of Small Intestinal Bacterial Overgrowth Syndrome. Betaine Hydrochloride is a source of supplemental Hydrochloric Acid that may eliminate Hypochlorhydria and therefore eliminate the underlying cause of Small Intestinal Bacterial Overgrowth Syndrome). [more info]

     

    Immune System

     

    Betaine Hydrochloride may prevent and treat Allergies (insufficient production of Hydrochloric Acid in the Stomach (Hypochlorhydria) is believed to be an underlying cause of some Allergies and Betaine Hydrochloride is a supplemental source of Hydrochloric Acid).

    Betaine Hydrochloride may suppress or kill Helicobacter pylori (Hypochlorhydria (lack of Hydrochloric Acid) patients have increased levels of Helicobacter pylori – Betaine Hydrochloride is a source of supplemental Hydrochloric Acid).

     

    Metabolism

     

    Betaine may improve Athletic Performance (by improving the body’s Energy levels, increasing Stamina and improving the body’s utilization of Oxygen).

    Betaine may increase the body’s Energy levels.

    Betaine may increase the Liver’s efficiency in metabolizing Fatty Acids.

     

    Betaine may reduce elevated Homocysteine levels (during its metabolism within the body, Betaine transfers one of its Methyl Groups to Homocysteine, causing Homocysteine to be converted to Methionine; Betaine, by losing one methyl group becomes Dimethyl Glycine (DMG)).

    Betaine may detoxify and stimulate the Liver:

    Betaine may help to prevent Cirrhosis.

    Betaine may help to prevent and reverse Fatty Liver.

    Betaine may improve the body’s utilization of Oxygen.

    Betaine may increase Stamina.

    #347
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    Keymaster

    Fruit Flies Use Alcohol as a Drug to Kill Parasites

     

    If fruit flies infected with wasps tap the alcohol in rotting fruit, it raises their blood-alcohol levels and their survival rates. The alcohol doesn’t just kill some of the wasps, it essentially liquifies them. ScienceDaily (Feb. 16, 2012) — Fruit flies infected with a blood-borne parasite consume alcohol to self-medicate, a behavior that greatly increases their survival rate, an Emory University study finds.–“We believe our results are the first to show that alcohol consumption can have a protective effect against infectious disease, and in particular against blood-borne parasites,” says Todd Schlenke, the evolutionary geneticist who led the research.–“It may be that fruit flies are uniquely adapted to using alcohol as medicine,” he adds, “but our data raise an important question: Could other organisms, perhaps even humans, control blood-borne parasites through high doses of alcohol?”—-Current Biology is publishing the study, co-authored by Emory graduate student Neil Milan and undergraduate student Balint Kacsoh.-The results add to the growing body of evidence that some animals know how to use toxic substances found in nature as medicine. Drosophila melanogaster, the common fruit fly that swirls around browning bananas in your kitchen, is an important biological model system. The Schlenke lab uses D. melanogaster to study how immune systems adapt to pathogens. The fly larvae eat the rot, or fungi and bacteria, that grows on overripe, fermenting fruit. “They’re essentially living in booze,” Schlenke says. “The amount of alcohol in their natural habitat can range from 5 to 15 percent. Imagine if everything that you ate and drank all day long was 5-percent alcohol. We wouldn’t be able to live like that, but fruit flies are really good at detoxifying alcohol.”–Tiny, endoparasitoid wasps are major killers of fruit flies. The wasps inject their eggs inside the fruit fly larvae, along with venom that aims to suppress their hosts’ immune response. If the venom is effective enough, the wasp egg hatches, and the wasp larva begins to eat the fruit fly larva from the inside out. Eventually, an adult wasp emerges from the remains of the fruit fly pupa. Some fruit flies, however, can overcome the effects of wasp venom and mount an immune response against wasp eggs. The blood cells in these fly larvae swarm over the wasp eggs and release nasty chemicals to kill them, allowing the fruit fly larvae to grow into adults.–“A constant co-evolutionary battle is going on between the immune systems of the flies and the venoms of the wasps,” Schlenke says. “Any new mechanism of defense that protects flies from wasps will tend to spread through fly populations by natural selection.” Schlenke wondered if the fruit flies could be tapping the toxic effects of alcohol in their natural habitat to fight off wasps.

    To test the theory, the researchers used a bisected petri dish filled with the yeast that fruit flies are normally fed in a lab environment. The yeast on one side of the dish was mixed with 6 percent alcohol, while the yeast on the other side remained alcohol-free. The researchers then released fruit fly larvae into the dish, allowing them to freely move to either side.

    After 24 hours, 80 percent of the fruit fly larvae that were infected with wasps were on the alcohol side of the dish, while only 30 percent of the non-infected fruit fly larvae were on the alcohol side.—“The strength of the result was surprising,” Schlenke says. “The infected fruit flies really do seem to purposely consume alcohol, and the alcohol consumption correlates to much higher survival rates.” Infected fruit flies that consumed alcohol beat out the wasps in about 60 percent of the cases, compared to a 0 percent survival rate for fruit fly controls that fed on plain yeast.–“The wasps aren’t as good as the flies at handling alcohol,” Schlenke says. A developing wasp knocked out within an alcohol-consuming fly larva dies in a particularly horrible way, he adds. “The wasp’s internal organs disperse and appear to be ejected out of its anus. It’s an unusual phenotype that we haven’t seen in our wasps before,” Schlenke says.—The lab repeated the experiment using another species of wasp that specializes in laying its eggs in D. melanogaster, rather than the generalist wasp used previously. Again, 80 percent of the infected flies wound up on the alcohol side of the dish, while only 30 percent of the uninfected flies did. But the alcohol diet was far less effective against the specialist wasps, killing them in only 10 percent of the cases.—“You would expect this kind of result,” Schlenke says, “since the generalist wasp species can attack plenty of other flies, but the specialist wasps are under strong pressure to adapt to the alcohol-infused habitat of D. melanogaster.”–The researchers hope that their data will lead to more studies of how alcohol may control pathogens in other organisms, including humans.—“Although many studies in humans have shown decreased immune function in chronic consumers of alcohol, little attempt has been made to assay any beneficial effect of acute or moderate alcohol use on parasite mortality or overall host fitness following infection,” Schlenke says. Story Source- The above story is reprinted from materials provided by Emory University. Note: Materials may be edited for content and length. For further information, please contact the source cited above. Journal Reference-Neil F. Milan, Balint Z. Kacsoh, Todd A. Schlenke. Alcohol Consumption as Self-Medication against Blood-Borne Parasites in the Fruit Fly. Current Biology, 2012; DOI: 10.1016/j.cub.2012.01.045

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    Recipe with alcohol—utilize any brandy or vodka or clean alcohol beverage—then add to it wormwood or clove or black walnut extract with the beverage or balm of gilead or bee Propolis and add 3 drops

     

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    B.C. paves way for all-in-one identity card-ID to start out as more secure CareCard

     

    The B.C. government is moving forward with plans for high-tech identity cards that will one day let people access a host of provincial services on the Internet. The province intends to sign a $20-million, six-year deal with Toronto-based SecureKey to provide card reader technology, the government says. It’s the latest in a series of new laws and contracts that pave the way for expanded government Internet services.–The cards may one day be used to access government websites for electronic health records, prescription histories, age verification, driver’s licence details, electronic voting and school registration for children. Currently, you have to visit a government office in person and show appropriate ID to access such services.–Health Minister Mike de Jong announced last May the government was developing new CareCards, with improved security features, to combat the millions of dollars lost to health insurance fraud.[U3]–Those cards should be available in November, and will roll out over the next five years. They’ll be free and mandatory for all British Columbians, requiring millions of people to re-enrol into the healthcare system. The project is expected to cost the government about $150 million.–People will also have the option of combining their new CareCard and driver’s licence into one B.C. Services Card.–The new government cards will have embedded security chips, similar to certain credit cards that allow customers to wirelessly make purchases by touching or waving their credit card in front of a terminal.–The government’s contract with SecureKey will develop B.C. card readers – key-sized devices that plug into a computer’s USB port. People tap their new CareCard or Services Card onto the SecureKey reader and enter a PIN number on a government website, to authenticate their identity.—There won’t be any online government services available when the cards launch in November. The province has proposed a rollout of features from different ministries over the next five years.–B.C. said it will directly award SecureKey a contract because the company already holds a contract with the federal government and the province wants its system to be compatible with Canada’s service.—NDP critic Doug Routley said the Liberal government has a dismal track record on protecting privacy and should have asked for other bids. “I know some pretty good roofers, but I’d still get three quotes on a roof,” he said. “It’d still be prudent to put this out there for competition.”–There remains many privacy questions about the direction the government is headed, said Vince Gogolek, executive director of the B.C. Freedom of Information and Privacy Association. He said the government rushed through legislation last fall that allows for crossministry sharing of personal information needed by the new cards.—The government said it is consulting with the independent privacy commission on the technology.–Identity cards won’t store any information inside their chips, and the SecureKey readers simply create a secure path and network to approve a person’s ID and re-direct them back to government information, officials said Friday.-The cards can be remotely cancelled if lost, and will only access the minimum amount of personal information required for a service – for example, a birth date to prove an age or a health number for prescriptions.

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    Nanoparticles in Food, Vitamins Could Harm Human Health

     

    ScienceDaily (Feb. 16, 2012) — Billions of engineered nanoparticles in foods and pharmaceuticals are ingested by humans daily, and new Cornell research warns they may be more harmful to health than previously thought.—A research collaboration led by Michael Shuler, the Samuel B. Eckert Professor of Chemical Engineering and the James and Marsha McCormick Chair of Biomedical Engineering, studied how large doses of polystyrene nanoparticles — a common, FDA-approved material found in substances from food additives to vitamins — affected how well chickens absorbed iron, an essential nutrient, into their cells.–The results were reported online Feb. 12 in the journal Nature Nanotechnology. According to the study, high-intensity, short-term exposure to the particles initially blocked iron absorption, whereas longer-term exposure caused intestinal cell structures to change, allowing for a compensating uptick in iron absorption.– The researchers tested both acute and chronic nanoparticle exposure using human gut cells in petri dishes as well as live chickens and reported matching results. They chose chickens because these animals absorb iron into their bodies similarly to humans, and they are also similarly sensitive to micronutrient deficiencies, explained Gretchen Mahler, Ph.D. ’08, the paper’s first author and former Cornell graduate student and postdoctoral associate.–The researchers used commercially available, 50-nanometer polystyrene carboxylated particles that are generally considered safe for human consumption. They found that following acute exposure, a few minutes to a few hours after consumption, both the absorption of iron in the in vitro cells and the chickens decreased.—But following exposure of 2 milligrams per kilogram for two weeks — a slower, more chronic intake — the structure of the intestinal villi began to change and increase in surface area. This was an effective physiological remodeling that led to increased iron absorption.–“This was a physiological response that was unexpected,” Mahler said.–Shuler noted that in some sense this intestinal villi remodeling was positive because it shows the body adapts to challenges. But it serves to underscore how such particles, which have been widely studied and considered safe, cause barely detectable changes that could lead to, for example, over-absorption of other, harmful compounds.[U4]–Human exposure to nanoparticles is only increasing, Shuler continued.–“Nanoparticles are entering our environment in many different ways,” Shuler said. “We have some assurance that at a gross level they are not harmful, but there may be more subtle effects that we need to worry about.”–The paper included Cornell co-authors Mandy Esch, a research associate in biomedical engineering; Elad Tako, a research associate at the Robert W. Holley Center for Agriculture and Health; Teresa Southard, assistant professor of biomedical sciences; Shivaun Archer, senior lecturer in biomedical engineering; and Raymond Glahn, senior scientist with the USDA Agricultural Research Service and courtesy associate professor in the Department of Food Science. The work was supported by the National Science Foundation; New York State Office of Science, Technology and Academic Research; Army Corp of Engineers; and U.S. Department of Agriculture.—Story Source-The above story is reprinted from materials provided by Cornell University, via Newswise. The original article was written by Anne Ju. –Journal Reference-Gretchen J. Mahler, Mandy B. Esch, Elad Tako, Teresa L. Southard, Shivaun D. Archer, Raymond P. Glahn, Michael L. Shuler. Oral exposure to polystyrene nanoparticles affects iron absorption. Nature Nanotechnology, 2012; DOI: 10.1038/nnano.2012.3

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    Building Bone from Cartilage- Orthopaedic Researchers Take the Road Less Travelled

    ScienceDaily (Feb. 14, 2012) — A person has a tumor removed from her femur. A soldier is struck by an improved explosive device and loses a portion of his tibia. A child undergoes chemotherapy for osteosarcoma but part of the bone dies as a result. Every year, millions of Americans sustain fractures that don’t heal or lose bone that isn’t successfully grafted. But a study presented at the Orthopaedic Research Society (ORS) 2012 Annual Meeting in San Francisco offers new hope for those who sustain these traumas. Orthopaedic researchers with the University of California, San Francisco (UCSF), Orthopaedic Trauma Institute, have found a very promising, novel way to regenerate bone. “Cartilage graft induces bone that actually integrates with the host bone and vascularizes it,” said Ralph S. Marcucio, PhD, Associate Professor, UCSF School of Medicine.–Cartilage graft is very different than the current methods used for bone grafting — autograft bone (a person’s own bone) or allograft materials (donor bone). For various reasons, these two grafting techniques can result in poor graft integration and osteonecrosis.—“With millions of bone grafting procedures performed every year in just the United States, developing improved technologies could directly enhance patient care and clinical outcomes,” Dr. Marcucio said.–Chelsea S. Bahney, PhD, Postdoctoral Scholar, UCSF School of Medicine, concedes their approach is less orthodox. “It is not the pathway that most people think about, but it made a lot more sense to follow the normal developmental mechanism.””This cartilage is naturally bioactive. It makes factors that help induce vascularization and bone formation,” added Dr. Bahney. “When people use a bone graft, it is often dead bone which requires something exogenous to be added to it or some property of the matrix in the graft.” Through a process called endochondral ossification, cartilage grafts produce new tissue that is very similar to the person’s own bone. Without additional properties to it, the researchers found the cartilage graft integrated well and was fully vascularized.–“We’re just taking a very similar cartilage that can induce bone formation, putting it into a bone defect and letting it just do its thing,” Dr. Marcucio said.—In the study, the researchers chose a non-stabilized tibial fracture callus as a source of a cartilage graft. “Healing of the transplanted cartilage grafts supported our hypothesis by producing a well-vascularized bone that integrated well with the host,” Dr. Bahney said.–“A cartilage graft could offer a promising alternative approach for stimulating bone regeneration,” Dr. Marcucio said. “Future work will focus on developing a translatable technology suitable for repairing bone through a cartilage intermediate at a clinical level.”–Story Source–The above story is reprinted from materials provided by Orthopaedic Research Society (ORS).

     

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    Show of the Week March 5 2012

     

    Scientists Prepare Test-tube Burger

     

    300,000 Organic Farmers Sue Monsanto in Federal Court

    Decision on March 31st to Go to Trial

     

    Secret GPS tracker terrifies Ontario man

     

    New Ability to Regrow Blood Vessels Holds Promise for Treatment of Heart Disease

     

    Colon Cleanse

     

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    Scientists Prepare Test-tube Burger
    CLIVE COOKSON – Financial Times (U.K.)
    I think there is going to be a tremendous emphasis on this. It will become a growing trend, because industrial cattle operations are going to become unprofitable due to the rising cost of water as it becomes scarcer. It takes 1,300 gallons of water to produce an eight ounce hamburger. As affluence increases across the world — not to be confused with wealth, only more than subsistence — eating meat will increase. The demands for ! water and grain (and the water it requires) will become unsustainable. The world’s first test-tube hamburger, created in a Dutch laboratory by growing muscle fibres from bovine stem cells, will be ready to grill in October, scientists believe.–‘I am planning to ask Heston Blumenthal [the celebrity chef] to cook it,” Mark Post, leader of the artificial meat project at Maastricht University in the Netherlands, told the American Association for the Advancement of Science annual meeting in Vancouver.–Researchers believe that meat grown in factories, rather than on farms, will be a more sustainable and less environmentally harmful source of food. Live cattle and pigs are only 15 per cent efficient at converting vegetable proteins to meat from the grass and cereals they eat[U5].–
    ‘If we can raise the efficiency from 15 to 50 per cent by growing meat in the lab, that would be a tremendous leap forward,” Professor Post said.—Starting with bovine stem cells[U6], the Dutch researchers have grown muscle fibres up to 3cm long and 0.5mm thick. The fibres are tethered and exercised as they grow, like real muscles, by bending and stretching in the culture dishes. They feed on a broth of vegetable proteins and other nutrients, equivalent to the grass or grain diet of cattle.[U7]—At present the fibres are a pallid yellowish-pink colour, rather than the red of raw ground beef, because they do not contain blood,[U8] but Prof Post plans to improve their appearance.–Patrick Brown, biochemistry professor at Stanford University in California, told the AAAS that global meat consumption was expected to double by 2050, yet livestock farming already accounted for 18 per cent of man-made greenhouse gas emissions and threatened biodiversity worldwide[U9].–
    To provide fat, an essential element in real burgers, They will be minced in with bovine fat cells are also being grown in the lab.the muscle fibres.—
    This project was started about six years ago, and I expect it will be another 10 to 20 years before we can mass-produce our meat,” Prof Post said.

    An anonymous individual has financed the Maastricht project with a €250,000 grant[U10]. He is expected to contribute further funds after the planned production of a ‘proof of concept” burger from the lab-grown muscle in October.

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    300,000 Organic Farmers Sue Monsanto in Federal Court: Decision on March 31st to Go to Trial

    The GMO movement is perhaps the leading example in our culture of how the greed of a single corporation can destabilize and entire ecosystem, thus effecting the lives of millions; all so a small group of people already rich can get richer. Nelson states, ‘Corporate control of our food system has led to the loss of millions of family farmers, destruction of our soil…”-Hundreds of citizens, (even including NYC chefs in their white chef hats) joined Occupy the Food System groups, ie Food Democracy Now, gathered outside the Federal Courts in Manhattan on January 31st, to support organic family farmers in their landmark lawsuit against Big Agribusiness giant Monsanto. (Organic Seed Growers & Trade Association v. Monsanto) Oral arguments were heard that day concerning the lawsuit by 83 plaintiffs representing over 300,000 organic farmers, organic seed growers, and organic seed businesses.—The lawsuit addresses the bizarre and shocking issue of Monsanto harassing and threatening organic farmers with lawsuits of ‘patent infringement” if any organic farmer ends up with any trace amount of GM seeds on their organic farmland.[U11] Judge Naomi Buckwald heard the oral arguments on Monsanto’s Motion to Dismiss, and the legal team from Public Patent Foundation represented the rights of American organic farmers against Monsanto, maker of GM seeds, [and additionally, Agent Orange, dioxin, etc.]—After hearing the arguments, Judge Buckwald stated that on March 31st she will hand down her decision on whether the lawsuit will move forward to trial.–Not only does this lawsuit debate the issue of Monsanto potentially ruining the organic farmers’ pure seeds and crops with the introduction of Monsanto’s genetically modified (GM) seeds anywhere near the organic farms, but additionally any nearby GM fields can withstand Monsanto’s Roundup herbicides, thus possibly further contaminating the organic farms nearby if Roundup is used.[U12]—Of course, the organic farmers don’t want anything to do with that ole contaminated GM seed in the first place. In fact, that is why they are certified organic farmers. But now they have to worry about getting sued by the very monster they abhor, and even have to spend extra money and land (for buffers which only sometimes deter the contaminated seed from being swept by the wind into their crop land). [U13]At this point, they are even having to resort to not growing at all the following organic plants: soybeans, corn, cotton, sugar beets, and canola, …just to protect themselves from having any (unwanted) plant that Monsanto could possibly sue them over.[U14]

     

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    Secret GPS tracker terrifies Ontario man

    An Ontario man says he’s angry and frightened after discovering someone hid a GPS tracking device under his vehicle, apparently to secretly monitor his movements.—“I was doing just a regular inspection on my truck and I found this black box under my truck … with flashing lights inside,” Ben Ferrill of Warsaw, Ont., told Go Public. “I didn’t know what it was. I didn’t know if it was a bomb. We were scared to death … It felt like a movie — unreal.”—After making the discovery last fall he reported it the next morning to the Ontario Provincial Police. Ferrill said the OPP tried to find out whom the device belonged to to lay a mischief charge, but were stymied in their investigation.—“I feel powerless. I can’t do anything about it and I really wish the police did more. I really wish they would do more — and I’m upset,” Ferrill said. Ferrill said he and his wife haven’t been able to sleep properly since, because they are worried someone is watching them.[U15] “We spent lots of nights up until three in the morning crying and talking about it — not sleeping and looking out the windows and being suspicious of vehicles that drive by,” Ferrill said. “Are they following me? Are they watching me? Are they going to try to do something to me? Are they going to try to do something to our family? The fear in finding something like that is unreal.”Ferrill’s lawyer, Ian Wilson, said is illegal to put a tracking device on someone else’s vehicle without their knowledge or consent unless there is a search warrant.—“The trouble is, we don’t know who is behind this,” Wilson said.[U16] The device Ferrill found, Wilson said, was sold by an American company, U.S. Fleet Tracking, which sells GPS systems to companies that want to track their fleet vehicles. The OPP obtained a production order, compelling the Canadian company that provides the wireless connection, Kore Wireless, to disclose whose device it is. However, Kore said it didn’t have that information[U17]. “I’ve [also] tried to get answers from Kore Wireless and their lawyer but they will tell me nothing,” Wilson said. Kore Wireless president Alex Brisbourne told CBC News his company only provides “connectivity. We don’t know who the end user is.”He said U.S. Fleet bills the customer and gives access to its website, where the customer can track its fleet vehicles in real time. “Our customer [U.S. Fleet] is in the United States. They have no responsibility or accountability to provide that information [to Canadian police],” Brisbourne said. When asked whether he requested the customer information from U.S. Fleet in this case, Brisbourne replied it “is not appropriate for us to ask for that. Security of information is particularly critical.” U.S. Fleet’s website makes it clear the company does not give up information easily, even to American authorities. “U.S. Fleet Tracking will not under any circumstance make your information or any data specific to your vehicle tracking account available to any third party — including local, state or federal law enforcement authorities [U18]… Even if presented with a court order, we promise to fight the courts to keep this information private and respect the privacy of our paying customers,” the website reads.

    Wilson and Ferrill said the OPP told them it would be too expensive and time-consuming to pursue the case through U.S. courts. The OPP told CBC News the file is now closed.–Ferrill insisted the device could not have been put there by his wife or any family member. In addition, U.S. Fleet sells to to businesses, not individuals.–He said the only dispute he is involved in is with his former employer, a car dealership in Peterborough, Ont.–Ferrill worked for a decade as a mechanic for Holiday Ford Lincoln. Two years ago, he injured his shoulder on the job. The Workplace Safety and Insurance Board (WSIB) in Ontario said he needed to be on light, restricted duty for several months.–After a few months, Holiday Ford fired him for allegedly stealing a bottle of windshield washer fluid.–A WSIB investigation found it was a pretext – that Ferrill had been fired because he was injured, which is a violation of the law. The WSIB report concluded: “A breach of their re-employment obligation has occurred.”Holiday Ford is appealing that decision, but it faces significant fines if the ruling stands. It is also facing a wrongful-dismissal lawsuit filed by Ferrill.–The company has denied Ferrill’s allegations in court filings.–Ferrill said he discovered the GPS device a few months after filing his lawsuit. He and his lawyer said they suspect the dealership could be involved, but they have no way of proving or disproving that.–CBC News left several messages with Ferrill’s former manager at Holiday Ford, but received no reply.–He has no idea how long it was there, and said the combined stress has pushed his family to the edge.–“Losing my job was really stressful, and then this is just a part of more stress,” Ferrill said. “It’s really testing our family. It’s the most stress and discomfort we have ever had.” Ferrill and his lawyer want Canadians to realize how technology can now be used against them and — at least in this case —there is no recourse.“It’s extremely frustrating to know that [customer] information exists in the U.S. somewhere … and we simply can’t get at it,” Wilson said. “[Ferrill] hasn’t had any peace of mind for the last 2½ years since he lost his job.”–Wilson said he finds it ironic this is happening to his client at the same time the federal government is talking about allowing police to monitor people’s internet use without a warrant.–“The same federal government that is responsible for this crime bill is also responsible for these wireless companies,” Wilson said.—He said he believes wireless companies in Canada should be required by law to know who the end users of the technology are: “This is a changing environment and steps have to be taken to protect people.” “We want to know who put this on our truck and why,” Ferrill said. “I’m sure whoever did this wants to do some type of harm to me, because whoever did this wants to know what I am doing all the time and wants to follow me for some reason.”

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    New Ability to Regrow Blood Vessels Holds Promise for Treatment of Heart Disease

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    Hindlimb ischemia was created in rats and treatments were delivered over seven days with an osmotic pump. The laser doppler imaging above shows the rat’s hind limb prior to treatment (on the left) and with increased blood flow (image on the right) just seven days after treatment.

    ScienceDaily (Feb. 16, 2012) — University of Texas at Austin researchers have demonstrated a new and more effective method for regrowing blood vessels in the heart and limbs — a research advancement that could have major implications for how we treat heart disease, the leading cause of death in the Western world.—The treatment method developed by Cockrell School of Engineering Assistant Professor Aaron Baker could allow doctors to bypass surgery and instead repair damaged blood vessels simply by injecting a lipid-incased substance into a patient. Once inside the body, the substance stimulates cell growth and spurs the growth of new blood vessels from pre-existing ones.—Aaron Baker is an assistant professor in the Department of Biomedical Engineering.—The method has been tested successfully on rats, and findings of the study were published recently in the Proceedings of the National Academy of Sciences –“Others have tried using growth factors to stimulate vessel growth in clinical trials and have not been successful,” said Baker, a faculty member in the school’s Department of Biomedical Engineering. “We think that a major reason for this is that previous methods assumed that the diseased tissues retained the ability to respond to a growth stimulus. Our method basically delivers extra components that can restore growth factor responsiveness to the tissue of patients with long-standing clinical disease.”—[U19] The ability to regrow blood vessels could prove crucial to treating chronic myocardial ischemia disease, which affects up to 27 million patients in the U.S. and leads to a reduction of blood flow in the heart and lower limbs — ultimately causing organ dysfunction and failure.–Central ischemia, which affects the heart, occurs when the coronary vessels that feed blood to the heart become blocked or narrow because of a buildup of fatty deposits called plaques. Such plaques are typically the result of a prolonged unhealthy diet or smoking, and factors such as age, high blood pressure and diabetes increase the risks of the disease, Baker said.

    Doctors have typically treated ischemia by physically opening the closed artery with a stent or surgically rerouting blood flow to the poorly perfused tissue. Both methods have limitations, however, and are not effective long-term.–The new method introduced by Baker and his research team builds on a promising revascularization approach that, up until now, has shown limited efficacy in clinical trials for treating human disease.—The method combines a growth factor — a substance capable of stimulating cellular growth, proliferation and cellular differentiation, as well as healing wounds — known as fibroblast growth factor 2 (FGF-2) with a lipid-embedded receptor to enhance its activity.—A challenge for scientists and engineers, however, has been getting FGF-2 to bind with cell receptors — the very molecules often found on the surface of the cell that receive chemical signals and direct activity in the cell from outside sources.—To overcome this, Baker’s method embeds the growth factors in synthetic lipid-based nanoparticles containing a coreceptor known as syndecan-4. The nanoparticles containing co-receptors that, when delivered with the growth factor, enable improved cell binding so that the growth factor can direct the targeted cell to divide, proliferate and form new cells for tissue regrowth.—The incased substance was injected into rats with hindlimb ischemia and stimulated a complete recovery from the ischemia in just seven days.—“We hope this research will increase our understanding of how tissues become resistant to revascularization therapies and may lead to more effective treatments for this widespread and debilitating disease,” said Baker, who was recognized last year with the National Institutes of Health Director’s New Innovator Award.-Story Source—The above story is reprinted from materials provided by University of Texas at Austin. -Journal Reference-E. Jang, H. Albadawi, M. T. Watkins, E. R. Edelman, A. B. Baker. Syndecan-4 proteoliposomes enhance fibroblast growth factor-2 (FGF-2)-induced proliferation, migration, and neovascularization of ischemic muscle. Proceedings of the National Academy of Sciences, 2012; 109 (5): 1679 DOI: 10.1073/pnas.1117885109

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    Colon Cleanse–

    add the whites of the Citrus -about 8 slices- then add 1 whole apple- add a pectin capsule ( if you wish not mandatory ) add bht 1 capsule-or any other antioxidant you see fit to add–example vitamin C-add sodium alginate 1 tsp -tumeric 1 tsp- bromelain powder or capsule 1 tablespoon -add 1/8 cup of water and allow to blend at slow to medium speed til it gelatinizes–once this is done pour into a glass container and consume several tsp through out the day and use a good load of water—this will bind to metals-toxins-will support the liver-digestive system-and potentially reduce fatty deposits in the gall bladder and liver

     

     

     

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    [U1]Horse (*&^ this a lie and a deception
    [U2]Should have Your Name—not dear customer
    [U3]Again the Excuse to Violate Privacy
    [U4]In other words if you are exposed to to other metals or poisons or foods that may produce a poison this will allow for a higher uptake of these contents further damaging the internals—and If there are air borne particles as well then what you may have is an exacbrated level of these being absorbed
    [U5]Well I wonder why!! Since the soy shuts down there thyroids and there pancreas how can the animal process anything accurately???—these GE or GMO foods are not meant for them to consume either
    [U6]Now am I the only one seeing this GMO MEAT or GE meat—playing with genetics to alter the dna of this meat and then feed it to the Human race—-we must be less then dust in the eyes of the powers that be!! Time to send them home!
    [U7]Vegetable Proteins—SOY or other GMO and this is going to be used in the Genetic sequencing—-now what does this do to People!!!
    [U8]Life is in the blood so what then is this—the is a design of food for something other then life as we know it—this is to feed something else and if people eat this then there will be health hazards
    [U9]Another lie—the green house gasses being emitted are not from the animals but rather the Bio diversity of the GMOs and there interference with the balance of this planet
    [U10]BG –Bill Gates—orrr my likely guess since he has financial power or perhaps the Vatican since they own the gmos and GE through monsanto
    [U11]The Law has to change if a seed is found on a piece of land then Monsanto is responsible for it so farmer do not lose there lands because of second hand negligence and this would contain or limit the amount of cross breeding of the seed with the real crop—the law is stacked in Monsanto’s favour and this needs to be addressed

    [U12]This is already happening —you cannot co exist in the real world—the moment you plant this abomination it corrupts what is naturally occurring—the biggest lie being perpetrated in the health food industry next to GMP —all Crap
    [U13]This would be enough for a lawsuit since it is on the land and there according to Monsanto illegally even the buffer doe not deter any kind of genetic anomaly with this barrier

    [U14]Not growing Soy or Canola or corn at this stage of the game may not be a bad idea

    [U15]Time to wake up –a truck driver is always being monitored

    [U16]The Question everyone should be asking is –what was he hauling that required him to be under surveillance—what could have been so important as to have this kind of Black opp to take place—the fact he was monitored is not an issue –truckers are always monitored but to have this kind of sophistication –there must have been something of the utmost importance—maybe a Bio contaminant for military use –maybe a military equipment needing to be transported unnoticed—who knows
    [U17]Now does this sound funny—I mean with everything today asking you for id and wanting to know if you had cornflakes or pancakes in the morning does this not see a touch odd “ they don’t know”
    [U18]I think this is good actually and more companies need to apply this kind of security—
    [U19]It is in the delivery —the fat could be a lipsome to carry to the area what is required for regenerating the issues

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    HOME

    Show Of The Week March 9 2012

     

    Food Fried in Olive or Sunflower Oil Is Not Linked to Heart Disease

     

    Stronger Intestinal Barrier May Prevent Cancer in the Rest of the Body

     

    Boosting Longevity With Good Bacteria

    The effect of hydro alcoholic Nettle (Urtica dioica) extracts on insulin sensitivity and some inflammatory indicators in patients with type 2 diabetes-

    What are you to do if you have a heart attack While you are alone

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    Food Fried in Olive or Sunflower Oil Is Not Linked to Heart Disease

    ScienceDaily (Jan. 24, 2012) — Eating food fried in olive or sunflower oil is not linked to heart disease or premature death, finds a paper published in the British Medical Journal online (bmj.com).-The authors stress, however, that their study took place in Spain, a Mediterranean country where olive or sunflower oil is used for frying and their results would probably not be the same in another country where solid and re-used oils were used for frying.–In Western countries, frying is one of the most common methods of cooking. When food is fried it becomes more calorific because the food absorbs the fat of the oils.[U1]–While eating lots of fried food can increase some heart disease risk factors such as high blood pressure, high cholesterol and obesity, a link between fried food and heart disease has not been fully investigated.—So the authors, led by Professor Pilar Guallar-Castillón from Autonomous University of Madrid, surveyed the cooking methods of 40,757 adults aged 29 to 69 over an 11-year period. None of the participants had heart disease when the study began. Trained interviewers asked participants about their diet and cooking methods. Fried food was defined as food for which frying was the only cooking method used. Questions were also asked about whether food was fried, battered, crumbed or sautéed.–The participants’ diet was divided into ranges of fried food consumption, the first quartile related to the lowest amount of fried food consumed and the fourth indicated the highest amount.–During the follow-up there were 606 events linked to heart disease and 1,134 deaths.—The authors conclude: “In a Mediterranean country where olive and sunflower oils are the most commonly used fats for frying, and where large amounts of fried foods are consumed both at and away from home, no association was observed between fried food consumption and the risk of coronary heart disease or death.”–In an accompanying editorial, Professor Michael Leitzmann from the University of Regensburg in Germany, says the study explodes the myth that “frying food is generally bad for the heart” but stresses that this “does not mean that frequent meals of fish and chips will have no health consequences.” He adds that specific aspects of frying food are relevant, such as the type of oil used.—Story Source- The above story is reprinted from materials provided by BMJ-British Medical Journal. Journal References-P. Guallar-Castillon, F. Rodriguez-Artalejo, E. Lopez-Garcia, L. M. Leon-Munoz, P. Amiano, E. Ardanaz, L. Arriola, A. Barricarte, G. Buckland, M.-D. Chirlaque, M. Dorronsoro, J.-M. Huerta, N. Larranaga, P. Marin, C. Martinez, E. Molina, C. Navarro, J. R. Quiros, L. Rodriguez, M. J. Sanchez, C. A. Gonzalez, C. Moreno-Iribas. Consumption of fried foods and risk of coronary heart disease: Spanish cohort of the European Prospective Investigation into Cancer and Nutrition study. BMJ, 2012; 344 (jan23 3): e363 DOI: 10.1136/bmj.e363—M. F. Leitzmann, T. Kurth. Fried foods and the risk of coronary heart disease. BMJ, 2012; 344 (jan23 3): d8274 DOI: 10.1136/bmj.d8274

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    Stronger Intestinal Barrier May Prevent Cancer in the Rest of the Body

    ScienceDaily (Feb. 21, 2012) — A leaky gut may be the root of some cancers forming in the rest of the body, a new study published online Feb. 21 in PLoS ONE by Thomas Jefferson University researchers suggests.—It appears that the hormone receptor guanylyl cyclase C (GC-C) — a previously identified tumor suppressor that exists in the intestinal tract — plays a key role in strengthening the body’s intestinal barrier, which helps separate the gut world from the rest of the body, and possibly keeps cancer at bay. Without the receptor, that barrier weakens.—A team led by Scott Waldman, M.D., Ph.D., chair of the Department of Pharmacology and Experimental Therapeutics at Jefferson and director of the Gastrointestinal Cancer Program at Jefferson’s Kimmel Cancer Center, discovered in a pre-clinical study that silencing GC-C in mice compromised the integrity of the intestinal barrier. It allowed inflammation to occur and cancer-causing agents to seep out into the body, damaging DNA and forming cancer outside the intestine, including in the liver, lung and lymph nodes.—Conversely, stimulating GC-C in intestines in mice strengthened the intestinal barrier opposing these pathological changes.—A weakened intestinal barrier has been linked to many diseases, like inflammatory bowel disease, asthma and food allergies, but this study provides fresh evidence that GC-C plays a role in the integrity of the intestine. Strengthening it, the team says, could potentially protect people against inflammation and cancer in the rest of the body.–“If the intestinal barrier breaks down, it becomes a portal for stuff in the outside world to leak into the inside world,” said Dr. Waldman. “When these worlds collide, it can cause many diseases, like inflammation and cancer.”–The role of GC-C outside the gut has remained largely elusive. Dr. Waldman and his team have previously shown its role as a tumor suppressor and biomarker that reveals occult metastases in lymph nodes. They’ve used to it better predict cancer risk, and have even shown a possible correlation with obesity.—Reporting in the Journal of Clinical Investigation, Dr. Waldman colleagues found that silencing GC-C affected appetite in mice, disrupting satiation and inducing obesity. Conversely, mice who expressed the hormone receptor knew when to call it quits at mealtime.–However, its role in intestinal barrier integrity, inflammation, and cancer outside the intestine is new territory in the field. A new drug containing GC-C is now on the verge of hitting the market, but its intended prescribed purpose is to treat constipation.–This study helps lays the groundwork, Dr. Waldman said, for future pre-clinical and clinical studies investigating GC-C’s abilities beyond those treatments in humans, including prevention and treatment of inflammatory bowel disease and cancer.”We’ve shown that when you pull away GC-C in animals, you disrupt the intestinal barrier, putting them at risk for getting inflammatory bowel disease and cancer. And when you treat them with hormones that activate GC-C it helps strengthen the integrity of the intestinal barrier,” Dr. Waldman said. “Now, if you want to prevent inflammation or cancer in humans, then we need to start thinking about feeding people hormones that activate GC-C to tighten up the barrier.”–Story Source–The above story is reprinted from materials provided by Thomas Jefferson University, via Newswise. —Journal References—Jieru Egeria Lin, Adam Eugene Snook, Peng Li, Brian Arthur Stoecker, Gilbert Won Kim, Michael Sullivan Magee, Alex Vladimir Mejia Garcia, Michael Anthony Valentino, Terry Hyslop, Stephanie Schulz, Scott Arthur Waldman. GUCY2C Opposes Systemic Genotoxic Tumorigenesis by Regulating AKT-Dependent Intestinal Barrier Integrity. PLoS ONE, 2012; 7 (2): e31686 DOI: 10.1371/journal.pone.0031686–Michael A. Valentino, Jieru E. Lin, Adam E. Snook, Peng Li, Gilbert W. Kim, Glen Marszalowicz, Michael S. Magee, Terry Hyslop, Stephanie Schulz, Scott A. Waldman. A uroguanylin-GUCY2C endocrine axis regulates feeding in mice. Journal of Clinical Investigation, 2011; 121 (9): 3578 DOI: 10.1172/JCI57925

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    Boosting Longevity With Good Bacteria

    ScienceDaily (Jan. 22, 2012) — A diet supplemented with a specific probiotic bacterial strain increases the lifespan of mice.—The mammalian gut is home to hundreds of bacterial species that contribute to food digestion and, in some cases, inflammatory gut diseases. Probiotics, beneficial bacterial species, can enhance gut health by keeping the resident bacteria in check. Now, a team of researchers at the RIKEN Innovation Center in Wako, including Mitsuharu Matsumoto, report that administration of the probiotic bacterial strain Bifidobacterium animalis subspecies lactis LKM512 to mice can lengthen their lifespan. Matsumoto and colleagues previously showed that LKM512 could reduce inflammatory markers in elderly humans and modify the makeup of intestinal bacteria2, but the effects of it on lifespan still required investigation. After starting 10-month-old mice on a diet including LKM512 for 11 months, the researchers found that LKM512-treated mice lived longer, had fewer skin lesions, and had better hair quality than untreated mice. Analyses of the gut of these mice revealed elevated gene expression in some bacterial species compared with control mice, indicating that LKM512 may improve gut health indirectly by regulating the levels of other bacterial species. The LKM512 treatment also prevented some age-related changes in bacterial composition of the gut, suggesting that the probiotic treatment protects the gut from developing characteristics associated with aging.—Acting as a barrier between the bacteria and food within the gut and the rest of the human body is an important role of the gut lining. Breakdown of this lining can cause infectious or inflammatory diseases. The researchers found that the gut of LKM512-treated mice served as a stronger barrier than the gut of control mice. LKM512 seemed to perform this function by increasing the expression of various proteins that maintain the tight connection between gut epithelial cells.-Polyamines are chemicals that reduce inflammation, and their levels decrease as an individual ages. Matsumoto and colleagues observed increases in intestinal polyamine levels in LKM512-treated mice, which may be caused by the greater numbers of bacteria promoted by LKM512. The increase in polyamines caused by LKM512 appeared to reduce inflammation in the body of the mice, as inflammatory markers in the blood and urine were lower in LKM512-treated mice compared with controls. In aged mice treated with LKM512, inflammatory marker levels were similar to those observed in younger mice, indicating that adults can benefit from probiotics.—“In future work, we hope to clarify the effectiveness of LKM512 in humans,” explains Matsumoto. If the findings extend to humans, inclusion of LKM512 into the human diet could enhance overall health and increase the human lifespan.—Story Source-The above story is reprinted from materials provided by RIKEN, via ResearchSEA.

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    The effect of hydro alcoholic Nettle (Urtica dioica) extracts on insulin sensitivity and some inflammatory indicators in patients with type 2 diabetes-

    Pak J Biol Sci. 2011 Aug 1;14(15):775-9-Authors: Namazi N, Esfanjani AT, Heshmati J, Bahrami A

    Abstract
    Type 2 diabetes is a metabolic disorder that is strongly associated with cardiovascular risk. Inflammation is a potential risk factor for cardiovascular disease. In this study, hydro alcoholic extract of Nettle (Urtica dioica) on insulin sensitivity and some inflammatory indicators in type 2 diabetic patients were studied. A randomized double-blind clinical trial on 50 men and women with type 2 diabetes was done for 8 weeks. Patients were adjusted by age, sex and duration of diabetes, then randomly divided into two groups, an intervention and control group. They received, 100 mg kg-1nettle extract or placebo in three portions a day for 8 weeks[U2]. Interleukin 6 (IL-6), Tumor Necrosis Factor-alpha (TNF-alpha), High Sensitive C-Reactive protein (hs-CRP) and Fasting Insulin concentration were measured. Insulin Sensitivity was calculated, at the beginning and the end of the study. The data were analyzed by SPSS version 18, p<0.05 was considered significant for all variables. After 8 weeks, IL-6 and hs-CRP showed a significant decrease in the intervention group compared to the control group (p<0.05). The findings showed that the hydro alcoholic extract of nettle has decreasing effects on IL-6 and hs-CRP in patients with type 2 diabetes after eight weeks intervention.–PMID: 22303583 [PubMed – indexed for MEDLINE]

    How to prepare this—take equal parts of either wine or vodka-or tequila or grappa Add to the slow cooker-then add equal portion of distilled water or RO water-NEVER TAP WATER—allow it to simmer for 3 days—strain it and bottle it and use it accordingly—measure off your body weight and go from there as it is stated in the comments—take your weight divide by 2.2 and then mutiply by 100mg this will give dosing for your body weight so in the case of a 180 lb person—they would go 180/2.2-=== 81 kgs then multiply by 100 and you get 8100 mgs or 8.1 grams which a teaspoon holds 5 grams so you would either do a tsp and a half+ or do more dosing qith just the one teaspoon—say you take one dose several times in his case 1. ½ + 3 times a day orr 1 tsp 5 times a day—so approximate on how you want to utilize this—

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    What are you to do if you have a heart attack While you are alone.

     

    The Johnson City Medical Center staff actually Discovered this and did an in-depth study On it in our ICU. The two individuals that discovered this then did An article on it, had it published and have had it incorporated into ACLS and CPR classes. It is very true and has and does work. It is called cough CPR. A cardiologist says it’s the truth If everyone who gets this sends it to 10 people,

    You can bet that we’ll save at least one life. It could save your life Let’s say it’s 6:15 p.m. And you’re driving home (alone of course), after an usually hard day on the job. You’re really tired, upset and frustrated. Suddenly you start experiencing severe pain In your chest that starts to radiate out Into your arm and up into your jaw. You are only about five miles from the hospital Nearest your home. Unfortunately you don’t know if you’ll be Able to make it that far. What can you do? You’ve been trained in CPR But the guy that taught the course didn’t tell You what to do if it happened to yourself Since many people are alone when they suffer a heart attack, this article seemed to be in order. Without help, the person whose heart is beating improperly and who begins to feel faint, Has only about 10 seconds left before losing consciousness. However, these victims can help themselves by coughing repeatedly and very vigorously. A deep breath should be taken before each Cough, and the cough must be deep And prolonged, as when producing sputum From deep inside the chest. A breath and a cough must be repeated About every two seconds without let up Until help arrives, or until the heart is felt to be beating normally again. Deep breaths get oxygen into the lungs and coughing movements squeeze the heart and Keep the blood circulating. The squeezing pressure on the heart also helps it regain normal rhythm. In this way, heart attack victims can get to a hospital. Tell as many other people as possible about this, it could save their lives! From Health Cares, Rochester General Hospital via Chapter 240s newsletter ‘AND THE BEAT GOES ON ‘ (reprint from The Mended Hearts, Inc. Publication, Heart Response

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    [U1]The question here is if this is not affecting the meditereanens then it is the type of foods perhaps they are frying and perhaps these foods are not genetically tampered with—this to would make the difference in the impact of the foods and oils used
    [U2]Take your body weight and divide by 2.2 and then multiply this by 100mgs to get the total of grams used—180lb person/2.2=81 kgs the Multiply by 100 and you would need approximately 8100mgs or 8.1 grams—approximately 1 tsp and and just slightly more then half

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    TOP C

    HOME

     

    Show of the Week March 12 2012

     

    Pfizer snaps up Emergen-C vitamin C maker

    Researchers Test Sugary Solution to Alzheimer’s Disease

     

    Stopping Hormone Therapy Might Help Breast Cancer to Regress

     

    Potential ‘Safe Period’ For Hormone Replacement Use Identified

     

    Long-Term Estrogen Therapy Linked To Breast Cancer Risk

     

    Estrogen Therapy May Be Associated With Kidney Stones in Postmenopausal Women

     

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    Pfizer snaps up Emergen-C vitamin C maker

    28-Feb-2012
    Drug giant Pfizer Inc. has added Alacer Corp., maker and distributor
    of Emergen-C products, to its Consumer Healthcare division.[U1]Financial terms of the
    transaction were not disclosed, but Alacer says it produces almost 500 million packets of
    Emergen-C annually, with products sold in health food stores, supermarkets,
    drug stores, mass merchandisers and club stores nationwide. [U2]We are very
    pleased that the Emergen-C family of products will become part of Pfizer’s portfolio said Paul
    Sturman, President of Pfizer Consumer Healthcare. We expect that our global network and
    deep expertise in dietary supplements combined with our desire to provide consumers with
    high-quality products will make Emergen-C more accessible than it has ever been before
    Emergen-C products add to and greatly complement our market-leading dietary supplement
    portfolio–Market Sales of vitamin C supplements – the biggest single category in the vitamins
    and minerals market – were up 2.8% to $221.27m in the year to October 1 across conventional
    and natural channels combined—While vitamin C sales were down 2.4% in the natural channel
    (natural supermarkets excluding Whole Foods) to $31.43m, they were up 3.7% in the
    conventional channel (FDMx) to $189.85m. In January, Pfizer CEO Ian Read told attendees
    at the JP Morgan Healthcare Conference in San Francisco that the company was still planning to
    offload its $1.87bn nutrition division, with Nestlé, Danone, Abbott Laboratories and Heinz still in
    the running. Last year, Pfizer agreed to sell hard-capsule manufacturer Capsugel for $2.375 billion
    in cash to an affiliate of Kohlberg Kravis Roberts &amp; Co L.P. (KKR). A spokesperson for Pfizer
    told NutraIngredients-USA.com: “The acquisition of Alacer Corp., will fall within Pfizer’s Consumer
    Healthcare business. As such, this doesn’t impact the evaluation of strategic options for our Nutrition
    business. “We have said that we would continue to pursue bolt-on business development activities
    that support our strategies. For example, in December 2011, we acquired Ferrosan’s consumer healthcare
    business, which strengthens our presence in dietary supplements as well as expand our footprint —
    Unique opportunity Ron Fugate, President and CEO of Alacer said that being acquired by Pfizer marked
    “the beginning of an exciting new chapter for Alacer and the Emergen-C health and wellness brand.
    By becoming part of Pfizer, we can access the resources and reach that will help us support healthy,
    active lifestyles across the globe.”[U3]

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    Researchers Test Sugary Solution to Alzheimer’s Disease

    ScienceDaily (Feb. 28, 2012) — Slowing or preventing the development of Alzheimer’s disease, a fatal brain condition expected to hit one in 85 people globally by 2050, may be as simple as ensuring a brain protein’s sugar levels are maintained.–That’s the conclusion seven researchers, including David Vocadlo, a Simon Fraser University chemistry professor and Canada Research Chair in Chemical Glycobiology, make in the latest issue of Nature Chemical Biology.-The journal has published the researchers’ latest paper “Increasing O-GlcNAc slows neurodegeneration and stabilizes tau against aggregation.”Vocadlo and his colleagues describe how they’ve used an inhibitor they’ve chemically created — Thiamet-G — to stop O-GlcNAcase, a naturally occurring enzyme, from depleting the protein Tau of sugar molecules.-“The general thinking in science,” says Vocadlo, “is that Tau stabilizes structures in the brain called microtubules. They are kind of like highways inside cells that allow cells to move things around.”—Previous research has shown that the linkage of these sugar molecules to proteins, like Tau, in cells is essential. In fact, says Vocadlo, researchers have tried but failed to rear mice that don’t have these sugar molecules attached to proteins.—Vocadlo, an accomplished chess player in his spare time, is having great success checkmating troublesome enzymes with inhibitors he and his students are creating in the SFU chemistry department’s Laboratory of Chemical Glycobiology.–Research prior to Vocadlo’s has shown that clumps of Tau from an Alzheimer brain have almost none of this sugar attached to them, and O-GlcNAcase is the enzyme that is robbing them.—Such clumping is an early event in the development of Alzheimer’s and the number of clumps correlate with the disease’s severity.–Scott Yuzwa and Xiaoyang Shan, grad students in Vocadlo’s lab, found that Thiamet-G blocks O-GlcNAcase from removing sugars off Tau in mice that drank water with a daily dose of the inhibitor. Yuzwa and Shan are co-first authors on this paper.—The research team found that mice given the inhibitor had fewer clumps of Tau and maintained healthier brains.–“This work shows targeting the enzyme O-GlcNAcase with inhibitors is a new potential approach to treating Alzheimer’s,” says Vocadlo. “This is vital since to date there are no treatments to slow its progression.–“A lot of effort is needed to tackle this disease and different approaches should be pursued to maximize the chance of successfully fighting it. In the short term, we need to develop better inhibitors of the enzyme and test them in mice. Once we have better inhibitors, they can be clinically tested. Story Source-The above story is reprinted from materials provided by Simon Fraser University. —Journal Reference-Scott A Yuzwa, Xiaoyang Shan, Matthew S Macauley, Thomas Clark, Yuliya Skorobogatko, Keith Vosseller, David J Vocadlo. Increasing O-GlcNAc slows neurodegeneration and stabilizes tau against aggregation. Nature Chemical Biology, 2012; DOI: 10.1038/nchembio.797

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    Stopping Hormone Therapy Might Help Breast Cancer to Regress

    ScienceDaily (Feb. 28, 2012) — As soon as women quit hormone therapy, their rates of new breast cancer decline, supporting the hypothesis that stopping hormones can lead to tumor regression, according to a report e-published in Cancer Epidemiology, Biomarkers, & Prevention.—As part of the national Breast Cancer Surveillance Consortium, researchers studied 741,681 woman-years of data (with a median of 3.3 years per woman) on 163,490 women aged 50-79 who were Group Health Cooperative members and had no prior history of breast cancer.–“This is the first study to look over time at screening mammography use among individual women by their hormone therapy status linked with their breast cancer diagnoses,” said lead author Diana S.M. Buist, PhD, a senior investigator at Group Health Research Institute.–Previous research has shown a rapid decline in new breast cancers — and also in use of hormone therapy and of screening mammography — since 2002, when the Women’s Health Initiative published that breast cancer rates were higher in women taking estrogen and progestin than in those taking either a placebo or only estrogen.—Some have suggested that the decline in use of hormone therapy may have caused the fall in the breast cancer rate, perhaps by making tumors regress, Dr. Buist explained. But others have countered that the explanation for the declines in both breast cancer and hormone use might instead be that because former hormone users are less concerned about breast cancer or see their doctors less often, they may get less screening mammography than do women who have never taken hormones.–“We set out to test this idea,” Dr. Buist said, “and our results seem to refute it.” Before 2002, former users of hormone therapy had lower rates of screening mammography than did current users. “But we found that this is no longer true,” she said. Indeed, former users had the same or even slightly higher screening rates than current users.—“We concluded that differences in rates of screening mammography don’t explain the declines in rates of the incidence of invasive breast cancer among women who’ve stopped using hormone therapy, Dr. Buist said. The National Cancer Institute, which supports the Breast Cancer Surveillance Consortium, funded this study. The collection of cancer data was also supported in part by several state public health departments and cancer registries throughout the United States.—In addition to Dr. Buist, the other co-authors were Diana L. Miglioretti, PhD, Rod Walker, MS, and Erin J. Aiello Bowles, MPH, of Group Health Research Institute; Walter Clinton, PhD, of Veterans Affairs (VA) Puget Sound Healthcare System; Patricia A. Carney, PhD, of Oregon Health & Science University, in Portland; Stephen H. Taplin, MD, MPH, of the National Cancer Institute; Tracy Onega, PhD, of Dartmouth Medical School, in Lebanon, NH; and Karla Kerlikowske, MD, of the University of California, San Francisco.-Story Source–The above story is reprinted from materials provided by Group Health Research Institute. \Journal Reference-Diana S.M. Buist, Rod Walker, Erin J. Aiello Bowles, Patricia A. Carney, Stephen H. Taplin, Tracy Onega, Karla Kerlikowske, Walter Clinton, and Diana L. Miglioretti. Screening Mammography Use among Current, Former, and Never Hormone Therapy Users May Not Explain Recent Declines in Breast Cancer Incidence. Cancer Epidemiol Biomarkers Prev, February 1, 2012 DOI: 10.1158/1055-9965.EPI-11-1115

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    Potential ‘Safe Period’ For Hormone Replacement Use Identified

    ScienceDaily (Feb. 8, 2009) — A new study makes important new findings on the role of hormone use on the risk of breast cancer, confirming that the use of estrogen plus progesterone increases the risk of both ductal and lobular breast cancer far more than estrogen-only; suggesting a two-year “safe” period for the use of estrogen and progesterone; and finding that the increased risk for ductal cancers observed in long-term past users of hormone replacement therapy drops off substantially two years after hormone use is stopped.–Previous studies have shown that hormone replacement therapy after menopause increases the risk of breast cancer and that use of a regimen that includes both estrogen and progesterone is more detrimental for the breast than the use of estrogen alone. But more data from large prospective studies are needed to fully characterize the impact of exogenous hormones (Exogenousor exogeneous) refers to an action or object coming from outside a system. It is the opposite of endogenous, something generated from within the system ) on breast cancer incidence by type of hormone preparation and histology of the cancer.—To investigate the association in more detail, American Cancer Society epidemiologists led by Eugenia E. Calle, PhD, did a prospective study of 68,369 postmenopausal women who were cancer-free at baseline in 1992. They examined the use of estrogen-only and estrogen and progesterone in current and former users of varying duration, and the subsequent risk of developing invasive ductal and lobular carcinoma of the breast. They also looked at whether the risk for each type of breast cancer and each type of hormone regimen varied by body mass index (BMI), stage of disease at diagnosis, and estrogen receptor (ER) and progesterone receptor (PR) status. For the present study, the follow-up period ended on June 30, 2005.—They confirmed the findings from previous work that estrogen and progesterone increases the risk of both ductal and lobular breast cancer far more estrogen alone. They also found the risk associated with use of estrogen and progesterone increases significantly and substantially within three years of beginning hormone use. The data showed no increased risk for women who used estrogen and progesterone for less than two years, potentially identifying a “safe” period for estrogen and progesterone use.—The study also found no increased risk of breast cancer in women who had stopped using estrogen and progesterone two or more years ago, suggesting a window of two to three years for the risks of estrogen and progesterone both to become apparent after initial use and to diminish after cessation. Few estimates of risk within two to three years of initiation and cessation are available, so these findings need replication in other large studies. The study found the use of estrogen and progesterone was associated with a doubling of risk of lobular cancer after three years of use, and a doubling of risk of ductal cancer with 10 years of use. Estrogen-only use was not associated with increased risk of ductal cancer, even after 20 years of use, but was associated with a 50 percent increase in risk of lobular cancer after 10 years of use.—Story Source: The above story is reprinted (with editorial adaptations by ScienceDaily staff) from materials provided by American Cancer Society, via EurekAlert!, a service of AAAS. — Journal Reference: –Eugenia E. Calle et al. —Postmenopausal hormone use and breast cancer associations differ by hormone regimen and histologic subtype. Cancer, Published Online: January 20, 2008 DOI: 10.1002/cncr.24101

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    Long-Term Estrogen Therapy Linked To Breast Cancer Risk

    ScienceDaily (May 9, 2006) — Long-term estrogen therapy may be related to a higher risk of breast cancer among postmenopausal women who have had a hysterectomy, according to an article in the May 8 issue of Archives of Internal Medicine, one of the JAMA/Archives journals. —Previous studies have linked the use of hormone therapy to breast cancer among postmenopausal women, but have primarily focused on the hormone combination of estrogen plus progestin, according to background information in the article. Recently released results from the Women’s Health Initiative (WHI), a large clinical trial of hormone therapy, found no significant link between estrogen therapy and breast cancer in women who took the hormone for seven years. —Wendy Y. Chen, M.D., M.P.H., Brigham and Women’s Hospital and Dana Farber Cancer Institute, Boston, and colleagues evaluated women who were part of the Nurses’ Health Study, a group of female nurses that have been followed since 1976. In 1980, 11,508 women from the study were postmenopausal and had had a hysterectomy. Every two years the researchers enrolled all the additional women who become postmenopausal and had a hysterectomy, so 28,835 women were included by the end of the study in 2002. Women were asked by questionnaire every two years if they used hormones and whether they had developed breast cancer. For women who developed breast cancer, the researchers obtained permission to review the women’s medical records, which they used to record the hormone receptor information. Tumors were classified as positive or negative for estrogen receptor or progesterone receptor based on how they responded to specific hormonal therapies. —Throughout the study period, 934 invasive breast cancers developed, 226 among women who had never used hormones and 708 among women who were using estrogen at the time. The longer a woman used estrogen, the higher her risk of breast cancer. Those who had been taking estrogen for fewer than 10 years did not appear to have a higher risk than those who had never taken hormones, but those who had been taking estrogen for more than 20 years had a significantly increased risk. The association was strongest for cancers that were estrogen receptor positive and progesterone receptor positive. The results were similar when the researchers evaluated only women who were older than age 60; only women who had begun estrogen therapy after reaching age 50; and only women who were at least age 50 and had undergone a hysterectomy, even if they had not gone through menopause. —“In conclusion, we found that estrogen therapy was associated with an increased risk of breast cancer with longer-term use,” the authors write. “Although current use of estrogen therapy for less than 10 years was not associated with a statistically significant increase in breast cancer risk, the WHI has shown an increased risk of stroke and deep-vein thrombosis in the same time period. Women who take estrogen therapy for prevention or treatment of osteoporosis typically require longer-term treatment and should thus explore other options, given the increased risk of breast cancer with longer-term use.”—(Arch Intern Med. 2006; 166: 1027-1032. Available pre-embargo to media at http://www.jamamedia.org.) –Editor’s Note: This study was supported by a grant from the National Institutes of Health, Bethesda, Md. —Story Source: The above story is reprinted (with editorial adaptations by ScienceDaily staff) from materials provided by JAMA and Archives Journals, via EurekAlert!, a service of AAAS —

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    Estrogen Therapy May Be Associated With Kidney Stones in Postmenopausal Women

    ScienceDaily (Oct. 12, 2010) — Use of estrogen therapy is associated with an increased risk of developing kidney stones in postmenopausal women, according to a report in the October 11 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.– “Nephrolithiasis [kidney stones] is a common condition that affects 5 percent to 7 percent of postmenopausal women in the United States,” according to background information in the article. “Because the process of kidney stone formation is influenced by a variety of lifestyle and other health-related factors, the true impact of estrogen therapy on the risk of kidney stone formation is difficult to infer from observational studies.” — Using data from the national Women’s Health Initiative study, Naim M. Maalouf, M.D., of the University of Texas Southwestern Medical Center, Dallas, examined data from two trials: 10,739 postmenopausal women with hysterectomy who received either an estrogen-only treatment or matching placebo and 16,608 postmenopausal women without hysterectomy who received either an estrogen plus progestin treatment or matching placebo. Data were collected for an average of 7.1 years in the estrogen-only trial and 5.6 years for the estrogen plus progestin trial. — A total of 335 cases of kidney stones were reported in the active treatment groups, while 284 cases occurred in the placebo groups. The beginning demographic characteristics and risk factors for kidney stones were similar in the two groups, and the authors found that estrogen therapy was associated with a significant increase in risk of kidney stones. The corresponding annualized incidence rate per 10,000 women per year was 39 in the treatment group and 34 in the placebo group. Development of kidney stones was five times more common in women with a history of kidney stones at the beginning of the study, but was not significantly altered by estrogen therapy. In this trial, estrogen therapy increased the risk of development of kidney stones irrespective of age, ethnicity, body mass index, prior hormone therapy use or use of coffee or thiazide diuretics.The authors conclude that their results “indicate that estrogen therapy increases the risk of nephrolithiasis in healthy postmenopausal women. The mechanisms underlying this higher propensity remain to be determined. In view of the sizable prevalence of nephrolithiasis in this segment of the population, these findings need to be considered in the decision-making process regarding postmenopausal estrogen use.”—Story Source:–The above story is reprinted (with editorial adaptations by ScienceDaily staff) from materials provided by JAMA and Archives Journals.–Journal Reference: N. M. Maalouf, A. H. Sato, B. J. Welch, B. V. Howard, B. B. Cochrane, K. Sakhaee, J. A. Robbins. Postmenopausal Hormone Use and the Risk of Nephrolithiasis: Results From the Women’s Health Initiative Hormone Therapy Trials. Archives of Internal Medicine, 2010; 170 (18): 1678 DOI: 10.1001/archinternmed.2010.342

     

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    [U1]I can almost bet there will be dilutions and contaminants in the product as of take over
    [U2]Imagine the amount of people getting the NEW and Improved Pfizer C
    [U3]What is happening is that the pharmaceuticals are going to take over the Nutraceutical brands—and with all the deregulating and re regulating going on the entrepreneur who does have a viable supplement will eventually be either litigated out or squeezed out—the fact they actually paid this much out to acquire this companies portfolio is the way it starts and eventually the FDA –DEA- Codex-EFSA will exterminate the ones that have something viable that works well with health conditions

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    Show of the Week March 16 2012

     

    T-UP-Sex Up Tea Recipe

     

    Activation of the nuclear receptor PPARγ by metabolites isolated from sage (Salvia officinalis L.).—for Diabetes

     

    Flavonol kaempferol improves chronic hyperglycemia-impaired pancreatic beta-cell viability and insulin secretory function.—-Health Benefits of Kaempferol

     

    Remedies for Respiratory-Heart-Sugar Issues

     

    Remedy for Heart Stability

     

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    T-UP-Sex Up Tea Recipe

    Ingredients—Psorlea-Dodder-Juniper berry-Nettle-Muira Purma-Celery Seed

    Tribulus-Shilajit- Deer Antler– put all in at equal parts—Designed to increase T levels—Stimulate the ebb and flow—regulate the insulin-regulate the kidneys-increase blood vessel flexibility—Use By either one of 2 steps—Step 1 blend all contents to a powder and then apply 1 tablespoon to a 2 cup pot of water ( preferably distilled or reverse osmosis ) and bring to a boil —when done pour into a cup and drink at least 3 servings a day and about 30 minutes before intercource—can be added with the T Up—Step 2 shake bag contents til there is a total mix—a and add to a 2 cup pot 1-2 tablespoons and bring to boil when that is done then allow the stove to be off and allow it to simmer for 5 minutes then drink

     

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    Activation of the nuclear receptor PPARγ by metabolites isolated from sage (Salvia officinalis L.).—for Diabetes

    Christensen KB, Jørgensen M, Kotowska D, Petersen RK, Kristiansen K, Christensen LP.

    Source –Institute of Chemical Engineering, Biotechnology and Environmental Technology, University of Southern Denmark, Niels Bohrs Allé 1, DK-5230 Odense M, Denmark. kbch@kbm.sdu.dk

    Abstract-ETHNOPHARMACOLOGICAL RELEVANCE:

    Salvia officinalis has been used as a traditional remedy against diabetes in many countries and its glucose-lowering effects have been demonstrated in animal studies. The active compounds and their possible mode of action are still unknown although it has been suggested that diterpenes may be responsible for the anti-diabetic effect of Salvia officinalis.

    AIM OF THE STUDY–To investigate whether the reported anti-diabetic effects of Salvia officinalis are related to activation of the nuclear receptor peroxisome proliferator-activated receptor (PPAR)γ and to identify the bioactive constituents.

    MATERIALS AND METHODS:

    From a dichloromethane extract of Salvia officinalis able to activate PPARγ several major metabolites were isolated by chromatographic techniques. To assess bioactivity of the isolated metabolites a PPARγ transactivation assay was used.

    RESULTS:

    Eight diterpenes were isolated and identified including a new abietane diterpene being the epirosmanol ester of 12-O-methyl carnosic acid and 20-hydroxyferruginol, which was isolated from Salvia officinalis for the first time, as well as viridiflorol, oleanolic acid, and α-linolenic acid. 12-O-methyl carnosic acid and α-linolenic acid were able to significantly activate PPARγ whereas the remaining metabolites were either unable to activate PPARγ or yielded insignificant activation.

    CONCLUSIONS:

    Selected metabolites from Salvia officinalis were able to activate PPARγ and hence, the anti-diabetic activity of this plant could in part be mediated through this nuclear receptor

     

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    Flavonol kaempferol improves chronic hyperglycemia-impaired pancreatic beta-cell viability and insulin secretory function.

    Zhang Y, Liu D.

    Source–Faculty of Life Science, Northwestern Polytechnical University, Xi’an, 710072, China.

    Considerable evidence shows that chronic hyperglycemia can cause pancreatic beta-cell dysfunction, which contributes to progressive deterioration of glucose homeostasis and overt diabetes. In the present study, we found that kaempferol, a flavonol compound present in various Chinese medicinal herbs, has cytoprotective effects on cultured clonal beta-cells and pancreatic human islets. Kaempferol treatment dose-dependently promoted viability, inhibited cellular apoptosis, and reduced caspase-3 activity in beta-cells and human islets exposed to chronic high glucose, with 10 μM kaempferol exerting the maximum effect. In addition, kaempferol treatment improved the expression of anti-apoptotic proteins Akt and Bcl-2 that was significantly reduced in beta-cells and human islets chronically exposed to hyperglycemia. Furthermore, exposure of beta-cells and human islets to kaempferol restored high glucose-attenuated intracellular cAMP and ATP production. Inhibition of protein kinase A or Akt activation ablated the anti-apoptotic effect of kaempferol. These cytoprotective effects of kaempferol were associated with improved insulin secretory function and synthesis in beta-cells and human islets. These findings provide evidence that kaempferol may be a naturally occurring anti-diabetic compound by protecting pancreatic beta-cell survival and function in a hostile environment that would otherwise lead to type 2 diabetes.—– Tea (black) (dry leaf)-126.96— Tea (green) (dry leaf)

    Health Benefits of Kaempferol—Keampferol is a strong antioxidant and helps to prevent oxidative damage of our cells, lipids and DNA. Kaempferol seems to prevent arteriosclerosis by inhibiting the oxidation of low density lipoprotein and the formation of platelets in the blood. Studies have also confirmed that kaempferol acts as a chemopreventive agent, which means that it inhibits the formation of cancer cells.

    An in vitro study by Jan Kowalski et al (Pharmacological Reports, 2005) showed that kaempferol inhibits monocyte chemoattractant protein (MCP-1). MCP-1 plays a role in the initial steps of atherosclerotic plaque formation.

    The flavonoids kaempferol and quercetin seems to act synergistically in reducing cell proliferation of cancer cells, meaning that the combined treatments with quercetin and kaempferol are more effective than the additive effects of each flavonoid. This was a conclusion from a study by ML Ackland et al (In Vivo, Feb 2005) titled “Synergistic antiproliferative action of the flavonols quercitin and kaempferol in cultured human cancer cell lines””.

    A study “Inhibition of P-glycoprotein function and expression by kaempferol and quercetin” by the Chiang Mai University, Thailand, found that kaempferol can help to fight cancer because it reduces the resistance of cancer cells to anti-cancer drugs such as vinbalstine and paclitaxel.
    Synonyms–Campherol, indigo yellow, nimbecetin, 3,4′,5,7-Tetrahydroxyflavone
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    Remedies for Respiratory-Heart-Sugar Issues

     

    Garlic-Sage- Bioflavonoid-Honey—Take 3-4 bulbs of garlic and 1 tablespoon of powdered Sage-8-9 pieces of the Bioflavonoids from citrus-add to 1-1/12 cup of unpasteurized honey—blend all the ingredients til there is a total fusion or the honey liquifies all the components—use 1 tsp as needed—this will clearly remove toxic waste and particulates that may occur in the system from respiratory to liver—this will dramatically reduce Sugar and sustain heart balance and flow—will increase permeability of the blood vessels—this will regulate the insulin as well from the sage and garlic will have strong antibacterial-antifungal properties-and potent antioxidant properties—

    Would be used for Respiratory-issues –Congestions and Cloggy lungs—Heart and Circulation-Permeability and Flow-Anti Plaque and Fat build up in arteries and liver-Immune Support to resist Bacteria and Fungal infections-Chelating elements and Pollutants out of the system

     

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    Remedy for Heart Stability

     

    Hawthorn Berry – Rose-Honey- Take ½ cup of Roses and Hawthorn berry and ½ cup of Unpasteurized Honey—add the Honey and get it going whipping it for about 5 minutes then add the other 2 ingredients slowly and pause in the loading-allowing the blender to fuse the honey and the components—then add more –repeat this til you completely empty your content—allow this to blend for about 15-20 minutes optimum speed or high speed—this will heat and completely saturate—when done stop blender—add to glass container—

    Use 1 tablespoon several times a day as a means to balance out heart irregularities

     

    Consuming rose and Hawthorn berry this will stabilize heart and allow for a steady heart rate—in conjunction to this you may want to utilize Taurine 500 mgs 2-3 times a day Magnesium Citrate 100-200 mgs 2-3 times a day

    And utilizing a good Vitamin E supplement 200-400 IU’s 2 times a day

     

    Consume adequate Salt and potassium as well to stabilize heart functions—

    At the same time ALL PROCESS SUGARS ARE TO CEASE—NO EXCEPTIONS—NO SYNTHETIC SWEETNERS—NO EXCEPTIONS-NO SOY BASED FOODS UNDER ANY CIRCUMSTANCE SINCE THIS LEACES OUT MAGNESIUM AS WELL AS VITAMIN E-NO EXCEPTIONS-ALL GRAINS AND CEREALS ARE TO CEASE-NO EXCEPTIONS

     

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    Show of the Week March 19 2012

     

    Identification of antiplatelet and acetylcholinesterase inhibitory constituents in betel nut

     

    Acetylcholinesterase inhibition in cognition-relevant brain areas of mice treated with a nootropic Amazonian herbal (Marapuama).

     

    Antioxidants from black tea may aid diabetics— Recipe For Sugar Regulating

     

    Garlic (Allium sativum) supplementation with standard antidiabetic agent provides better diabetic control in type 2 diabetes patients

     

    Exercise and Caffeine Change Your DNA in the Same Way

     

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    Identification of antiplatelet and acetylcholinesterase inhibitory constituents in betel nut.

    Zhong Xi Yi Jie He Xue Bao. 2011 Jun;9(6):619-25—Authors: Ghayur MN, Kazim SF, Rasheed H, Khalid A, Jumani MI, Choudhary MI, Gilani AH

    OBJECTIVE: To investigate the possible mechanism and the compound(s) responsible for the antiplatelet and acetylcholinesterase (AChE) inhibitory effects of Areca catechu crude extract (Ac.Cr).
    METHODS: Aqueous-methanol (70%) was used for extraction of plant material (betel nut). Antiplatelet activity was measured in human platelet-rich plasma by using a Lumi-aggregometer while anti-AChE activity was measured spectrophotometrically in vitro. In an attempt to find the responsible compound(s) in betel nut for antiplatelet and anti-AChE activities, different commercially available betel nut compounds were tested.
    RESULTS: Ac.Cr inhibited platelet aggregation induced by arachidonic acid (AA), adenosine diphosphate (ADP), platelet-activating factor (PAF), epinephrine and Ca(2+)-ionophore. Ac.Cr was the most potent in inhibiting ADP- and Ca(2+)-ionophore-induced aggregation. In the AChE assay, Ac.Cr showed significant AChE inhibitory activity with almost complete inhibition of the enzyme. Out of the tested compounds, none of the compounds in betel nut showed any antiplatelet effect except for catechin that was the most potent against epinephrine-induced aggregation. Catechin was significantly less potent than Ac.Cr, indicating a presence of additional compound(s) with antiplatelet activity. For the AChE inhibitory effect, only tannic acid, gallic acid, diosgenin and isoguvacine were found to be active, whereby tannic acid was more potent than Ac.Cr.
    CONCLUSION: This study shows the possible antiplatelet and AChE inhibitory potential of betel nut while further studies are needed to confirm and identify more compounds in betel nut for these actions.–PMID: 21669165 [PubMed – indexed for MEDLINE]

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    Acetylcholinesterase inhibition in cognition-relevant brain areas of mice treated with a nootropic Amazonian herbal (Marapuama).

    Phytomedicine. 2010 Sep 10;

    Authors: Figueiró M, Ilha J, Pochmann D, Porciúncula LO, Xavier LL, Achaval M, Nunes DS, Elisabetsky E

    The goal of acetylcholinesterase inhibitors (AChEIs) used to treat Alzheimer’s patients is an improvement in cholinergic transmission. While currently available AChEIs have limited success, a huge impediment to the development of newer ones is access to the relevant brain areas. Promnesic, anti-amnesic and AChEI properties were identified in a standardized ethanol extract from Ptychopetalum olacoides (POEE), a medicinal plant favored by the elderly in Amazon communities. The purpose of this study was to provide conclusive evidence that orally given POEE induces AChE inhibition in brain areas relevant to cognition. Histochemistry experiments confirmed that the anticholinesterase compound(s) present in POEE are orally bioavailable, inducing meaningful AChE inhibition in the hippocampus CA1 (â¼33%) and CA3 (â¼20%), and striatum (â¼17%). Ellman’s colorimetric analysis revealed that G1 and G4 AChE isoforms activities were markedly inhibited (66 and 72%, respectively) in hippocampus and frontal cortex (50 and 63%, respectively), while G4 appeared to be selectively inhibited (72%) in the striatum. Western blotting showed that POEE did not induce significant changes in the AChE immunocontent suggesting that its synthesis is not extensively modified. This study provides definitive proof of meaningful anticholinesterase activity compatible with the observed promnesic and anti-amnesic effects of POEE in mice, reaffirming the potential of this extract for treating neurodegenerative conditions where a hypofunctioning cholinergic neurotransmission is prominent. Adequate assessment of the safety and efficacy of this extract and/or its isolated active compound(s) are warranted.—PMID: 20833520 [PubMed – as supplied by publisher]

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    Garlic (Allium sativum) supplementation with standard antidiabetic agent provides better diabetic control in type 2 diabetes patients.

    Pak J Pharm Sci. 2011 Oct;24(4):565-70–Authors: Ashraf R, Khan RA, Ashraf I

    Abstract
    Garlic has been used safely since ancient times as both food and medicine in human populations, but studies of its efficacy in the management of diabetes have yielded conflicting results. This study has evaluated the potential hypoglycemic effects of garlic in type 2 diabetic patients. The study was conducted in diagnosed type 2 diabetic patients (n=60) with fasting blood sugar level above 126 mg/dl to evaluate the effects of adding garlic tablets with standard antidiabetic therapy on blood sugar. Patients were divided randomly into 2 groups. Group 1 (n=30) was given tablet Garlic (KWAI) 300 mg thrice daily + Metformin 500 mg twice daily and Group 2 (n=30) was given Placebo+Metformin 500 mg twice daily respectively for 24 weeks. Serum lipids and fasting blood glucose were measured at week 0, 12 and week 24. Group1 showed significant reduction in fasting blood sugar at week 24 with a percentage decrease of (-3.12 percent) (P = <0.005) as compared to group 2 (0.59 percent). At the end of week 24, GR1 group also showed considerable decrease in mean total cholesterol (6.2 mg/dl, -2.82%, P=<0.005), LDL-C (-3 mg/dl, 2.18% P=<0.005), triglycerides (-5.2 mg/dl, 3.12%, P<0.005) while HDL cholesterol was significantly increased (2.36 mg/dl, 6.72%, P<0.005) as compared to GR2 group. Combination of garlic with typical antidiabetic remedy has shown to improve glycemic control in addition to antihyperlipidemic activity. Garlic may be a good addition in the management of patients with diabetes and hyperlipidemia.—PMID: 21959822 [PubMed – indexed for MEDLINE]

    Recipe—take a garlic extract or supplement and add with it juniper berry and bitter melon—this should in fact increase the efficiency of the organs in regulating insulin—repairing the pancreas—assisting the liver—–this should reduce not only the cholesterol but as well the sugar in the system

    You can mix equal parts of an extract or tincture of the juniper 1/3 or 33 % -bitter melon 1/3 or 33%-and garlic 1/3 or 33% in a 1 oz or 2 oz glass container and utilize ¼ tsp 3 times a day  either after a meal or before bed

    You can as well take the garlic supplement and utilize the tincture of bitter melon and juniper either mixed or separate then use ¼ tsp of each and 1 capsule of garlic

    You can take a capsule of each 1— 3 times a day—even though they used the KWAI product the Kyolic will do well formulas like 108-or 110 will be adequate or even just the plain 100

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    Exercise and Caffeine Change Your DNA in the Same Way

     

    You might think that the DNA you inherited is one thing that you absolutely can’t do anything about, but in one sense you’d be wrong. Researchers have found that when healthy but inactive men and women exercise for a matter of minutes, it produces a rather immediate change to their DNA. Perhaps even more tantalizing, the study suggests that the caffeine in your morning coffee might also influence muscle in essentially the same way. —The underlying genetic code in human muscle isn’t changed with exercise, but the DNA molecules within those muscles are chemically and structurally altered in very important ways. Those modifications to the DNA at precise locations appear to be early events in the genetic reprogramming of muscle for strength and, ultimately, in the structural and metabolic benefits of exercise.–“Our muscles are really plastic,” says Juleen Zierath of Karolinska Institutet in Sweden. “We often say “You are what you eat.” Well, muscle adapts to what you do.  If you don’t use it, you lose it, and this is one of the mechanisms that allows that to happen.”—The DNA changes in question are known as epigenetic modifications and involve the gain or loss of chemical marks on DNA over and above the familiar sequence of As, Gs, Ts, and Cs. The new study shows that the DNA within skeletal muscle taken from people after a burst of exercise bears fewer chemical marks (specifically methyl groups) than it did before exercise. Those changes take place in stretches of DNA that are involved in turning “on” genes important for muscles’ adaptation to exercise.—When the researchers made muscles contract in lab dishes, they saw a similar loss of DNA methyl groups. Exposure of isolated muscle to caffeine had the same effect.–Zierath explained that caffeine does mimic the muscle contraction that comes with exercise in other ways, too. She doesn’t necessarily recommend anyone drink a cup of joe in place of exercise. It’s nevertheless tempting to think that athletes who enjoy a coffee with their workout might just be on to something.—Broadly speaking, the findings offer more evidence that our genomes are much more dynamic than they are often given credit for. Epigenetic modifications that turn genes on and back off again can be incredibly flexible events. They allow the DNA in our cells to adjust as the environment shifts.—“Exercise is medicine,” Zierath says, and it seems the means to alter our genomes for better health may be only a jog away. And for those who can’t exercise, the new findings might point the way to medicines (caffeinated ones, perhaps?) with -Story Source–The above story is reprinted from materials provided by Cell Press, via EurekAlert!, a service of AAAS. –Journal Reference-Romain Barrès, Jie Yan, Brendan Egan, Jonas Thue Treebak, Morten Rasmussen, Tomas Fritz, Kenneth Caidahl, Anna Krook, Donal J. O’Gorman, Juleen R. Zierath. Acute Exercise Remodels Promoter Methylation in Human Skeletal Muscle. Cell Metabolism, 2012; 15 (3): 405 DOI: 10.1016/j.cmet.2012.01.001

     

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    Antioxidants from black tea may aid diabetics
    Polysaccharides from black tea may blunt the spike in sugar levels after a meal more than similar compounds from green and oolong tea, and offer potential to manage diabetes, says a new study.

    The black tea polysaccharides also exhibited the greatest activity for scavenging free radicals, which are linked to development of diseases such as cancer and rheumatoid arthritis, according to new findings published in the Journal of Food Science. Interest in tea and its constituents has bloomed in recent years, with the greatest focus on the leaf’s polyphenol content. Green tea contains between 30 and 40 per cent of water-extractable polyphenols, while black tea (green tea that has been oxidized by fermentation) contains between 3 and 10 per cent. Oolong tea is semi-fermented tea and is somewhere between green and black tea. The new research looked at the polysaccharide content of green, black and oolong tea, and measured their ability to inhibit the effects of alpha-glucosidase activity. By inhibiting this carbohydrate hydrolyzing enzyme, it is possible to reduce the spike in glucose levels in the blood following a meal (postprandial hyperglycemia). If additional studies support the potential effects of the polysaccharides, it could see the black tea extracts positioned in the diabetic supplements market.

    Study details

    “Many efforts have been made to search for effective glucose inhibitors from natural materials,” said lead researcher Haixia Chen. “There is a potential for exploitation of black tea polysaccharide in managing diabetes.” Researchers from Tianjin University isolated three polysaccharide-rich fractions from green, black, and oolong tea. The black tea was found to contain lower molecular weight polysaccharides. Green tea had a range from 9.2 to 251.5 KDa, while black tea polysaccharides ranged from 3.8 to 32.7 KDa. When tested for their ability to inhibit alpha-glucosidase, as well as antioxidant activities relating to hydroxyl radicals and DPPH radicals, the black tea polysaccharides were found to produce the best results, said Chen and co-workers. “The differences in antioxidant activities and glycosidase inhibitory properties among the three polysaccharide-rich fractions appeared to be related to differences in monosaccharide composition and molecular weight distribution of the polysaccharide,” wrote the researchers. —-“Physicochemical Properties and Antioxidant Capacity of 3 Polysaccharides from Green Tea, Oolong Tea, and Black Tea”–Authors: H. Chen, Z. Qu, L. Fu, P. Dong, X. Zhang

    Recipe For Sugar Regulating—take Black Tea and Sage and make a brew out of them—and drink through out the day to minimize the ravages of sugar—this can assist in the reduction of the medications and increase the restoration of the Pancreas

    Orrrr

    Use Black Coffee and Sage as well—utilize equal parts of both the sage and the Tea or Coffee
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    Show of the Week March 23 2012

    Onion or  Garlic

     

    Urtica Dioica (Nettle)

     

    Induction of insulin secretion by a component of Urtica dioica leave extract in perifused Islets of Langerhans and its in vivo effects in normal

     

    Inhibition of severe acute respiratory syndrome coronavirus replication in a lethal SARS-CoV BALB

     

    Health benefits of Savory

     

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    Onion or  Garlic

    4.13. Allium Sativum L. and Allium Cepa (Garlic and Onion)

    Prophet Mohammad (PBUH) said “although onion and garlic have a bad smell, they are cures for 70 different illnesses that cannot be cured by any other means”. Onion (A. cepa) and garlic (A. sativa) are closely related vegetables that belong to the Allium class of bulb-shaped plants, which also includes chives, leeks, and scallions. Garlic is used for flavoring in cooking and is unique due to its high sulfur content, along with arginine, oligosaccharides, flavonoids, and selenium, all of which might promote health [116]. The association between the consumption of Allium vegetables and the risk for cancer was assessed in several epidemiologic studies, showing the protective effect of garlic and onion on cancer. In China, high consumption of Allium vegetables was associated with lower incidence of gastric cancer [117, 118]. Additional studies in the Netherlands suggested an inverse correlation between the risk of colorectal, breast, and lung cancers and the consumption of onion and garlic [119]. Steinmetz et al. [120] studied the association between garlic consumption and the risk of colon cancer and found that women who consumed high amounts of garlic had a 50 percent lower incidence of distal colon cancer compared with women who consumed less garlic [120]. The risk of breast cancer was also found to be reduced in women consuming greater amounts of fiber garlic and onions [31], as well as that of esophageal and stomach cancers [121]. Similar findings were noted with reference to the risk of prostate cancer [122, 123], pancreatic cancer [33], and other known cancer types [124]. The amount of garlic consumed in the above studies varied from 2 to 20 g daily (The World Health Organization (WHO) guidelines for general health promotion for adults recommend a daily dose of 2 to 5 g of fresh garlic). It was noted that although garlic had been used safely in cooking, excessive consumption can cause some side effects, in addition to those of strong breath and body odors [125]. The protective effect of Allium vegetables against tumor progression and against angiogenesis were attributed to its organosulfur compounds especially allicin (an active compound in garlic) and diallyl disulfide [126]. Such compounds are able to block the formation of cancer-causing substances [127], halt the activation of cancer-causing substances [128, 129], enhance DNA repair [130], reduce cell proliferation, or induce apoptosis-programmed cell death (Table 1 and [126, 131]).

     

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    Urtica Dioica (Nettle)

    The origin of its Latin name, Urtica, means “I burn”, indicative of the stings caused by glandular hairs on the leaves that contain formic acid and histamine, two agents known to cause the stinging and skin irritation after contact. U. dioica leaf has a long history as an herbal remedy and nutritious addition to the diet. Nettle leaves are a rich source of essential amino acids, ascorbic acid, several mineral element, and vitamins, such as iron, provitamin A, and vitamin C [113]. Nettle extracts can be used to treat arthritis, hay fever, kidney problems, pain, and anemia. Nettle extracts possess hypoglycaemic properties and improve glucose tolerance [35]. U. dioica is believed to be antioxidant, immunesuppressive, antirheumatoid, antiulcer, anti-inflammatory, and anticarcinogenic [14]. Indeed, its leaf [114] and roots [115] extracts were effective against prostate cancer proliferation.

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    Induction of insulin secretion by a component of Urtica dioica leave extract in perifused Islets of Langerhans and its in vivo effects in normal and streptozotocin diabetic rats.
    Farzami B, Ahmadvand D, Vardasbi S, Majin FJ, Khaghani Sh.

    Source
    Department of Medical Biochemistry, Tehran University of Medical Sciences, P.O. Box 14155-5399, Tehran, Iran. Bfarzamj@neda.net

    Abstract
    The blood glucose lowering effect of Urtica dioica (Stinging Nettle) as a medicinal plant has been noted in old writings such as those of Avicenna. Recently, there has also been other investigators that indicated the hypoglycemic effect of Urtica dioica. But so far, the mechanism of this effect has not been deduced. In this report, a perifusion system is arranged in which an exact number of Langerhans Islets were exposed to several fractions of extracts of Urtica dioica by TLC. The active ingredient fraction named F(1), caused a marked increase in insulin secretion. A simultaneous assay of glucose showed that the increase in insulin level was associated with a decrease in glucose level. Furthermore, the active component of Urtica dioica was found to increase the insulin content of blood sera in normal and streptozotocin diabetic rats that were injected intraperitoneally (i.p.) with the active ingredient of the extract. The in vivo studies presented in this report show that not only an increase in insulin level of blood sera was observed in rats after 30 min from the initial point of injection but a simultaneous decrease of blood sugar was detected when similar sera was tested for glucose. The increase in insulin level was six times during the 120 min of our determination. The decrease in blood sugar was found to be similar both in the level and time of initiation. On the basis of our findings, we assume that F(1) is the active ingredient of plant leaves extract. The results show that the blood lowering effect of the extract was due to the enhancement of insulin secretion by Langerhance Isletes.

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    Inhibition of severe acute respiratory syndrome coronavirus replication in a lethal SARS-CoV BALB/c mouse model by stinging nettle lectin, Urtica dioica agglutinin.
    Kumaki Y, Wandersee MK, Smith AJ, Zhou Y, Simmons G, Nelson NM, Bailey KW, Vest ZG, Li JK, Chan PK, Smee DF, Barnard DL.

    Source—Institute for Antiviral Research, Department of Animal, Dairy and Veterinary Science, 5600 Old Main Hill, Utah State University, Logan, UT 84322, USA.
    Abstract——- Urtica dioica agglutinin (UDA) is a small plant monomeric lectin, 8.7 kDa in size, with an N-acetylglucosamine specificity that inhibits viruses from Nidovirales in vitro. In the current study, we first examined the efficacy of UDA on the replication of different SARS-CoV strains in Vero 76 cells. UDA inhibited virus replication in a dose-dependent manner and reduced virus yields of the Urbani strain by 90% at 1.1 ± 0.4 μg/ml in Vero 76 cells. Then, UDA was tested for efficacy in a lethal SARS-CoV-infected BALB/c mouse model. BALB/c mice were infected with two LD50 (575 PFU) of virus for 4 h before the mice were treated intraperitoneally with UDA at 20, 10, 5 or 0 mg/kg/day for 4 days. Treatment with UDA at 5 mg/kg significantly protected the mice against a lethal infection with mouse-adapted SARS-CoV (p < 0.001), but did not significantly reduce virus lung titers. All virus-infected mice receiving UDA treatments were also significantly protected against weight loss (p < 0.001). UDA also effectively reduced lung pathology scores. At day 6 after virus exposure, all groups of mice receiving UDA had much lower lung weights than did the placebo-treated mice. Thus, our data suggest that UDA treatment of SARS infection in mice leads to a substantial therapeutic effect that protects mice against death and weight loss. Furthermore, the mode of action of UDA in vitro was further investigated using live SARS-CoV Urbani strain virus and retroviral particles pseudotyped with SARS-CoV spike (S). UDA specifically inhibited the replication of live SARS-CoV or SARS-CoV pseudotyped virus when added just before, but not after, adsorption. These data suggested that UDA likely inhibits SARS-CoV infection by targeting early stages of the replication cycle, namely, adsorption or penetration. In addition, we demonstrated that UDA neutralizes the virus infectivity, presumably by binding to the SARS-CoV spike (S) glycoprotein. Finally, the target molecule for the inhibition of virus replication was partially characterized. When UDA was exposed to N-acetylglucosamine and then UDA was added to cells just prior to adsorption, UDA did not inhibit the virus infection. These data support the conclusion that UDA might bind to N-acetylglucosamine-like residues present on the glycosylated envelope glycoproteins, thereby preventing virus attachment to cells.
    Recipe for Nettle–Make a tea with this by adding ¼ cup of nettle to a pot of water ( distilled ) bring to a boil  and when boiled turn off and pour—you can as well fuse this with other herbs such as black tea –sage or do all 2 to increase the immune and sugar regulating functions as well and will synergize t o increase the potency of the properties of each herb

     

    Ancient Remedial Use of Nettle—-Horse Nettle, Bull Nettle. S. E. United States.—The fresh juice of the fruit is concentrated by exposure to currents of air at a low temperature and preserved by the addition of some alcohol. This is the process. adopted by McHoy, Howe Co., of Indianapolis. They prepare it double strength. It is recommended largely in the treatment of epilepsy. Powder of the root has during recent years gained some repute as a remedy in infantile and hysterieal convulsions, but chiefly in epilepsy and paroxysms connected with menstrual derangements. Dose of Pdr. Root 10 grs. to 1 dr.—–The roots, leaves and tops are a positive, stimulating, tonic astringent; a powerful arrester of hemorrhages whether of the nose, lungs, stomach, bowels, uterus or urinary organs. It will also stop hemorrhages when applied locally and relieve painful hemorrhoids. The Fluid Extract when diluted forms a good wash for some eczemas

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    Health benefits of Savory
    §         Savory leaves and tender shoots contain incredibly high quality chemical compounds that are known to have anti-oxidant, disease preventing and health promoting properties.  In addition, dietary fiber in this herb helps reduce LDL or bad cholesterol while increasing HDL or good cholesterol levels.

    §         Savory leaves contain many essential volatile oils phenols such as thymol and carvacrol, as well as linalool, camphene, caryophyllene, terpineol, myrcene, and other terpenoids.

    §         Thymol, one of the important essential oils, has scientificaly been found to have antiseptic, anti-fungal characteristics.

    §         In addition, another phenolic compound, carvacrol in savory inhibits the growth of several bacteria strains like E. coli and Bacillus cereus. Carvacol, therefore, has been used as food additive for its anti-bacterial properties and in addition, it gives pleasant tangy taste and marjoram like smell to the food.

    §         Savory herb is an excellent source of minerals and vitamins that are essential for optimum health. Its leaves and tender shoots are one of the richest source of potasium, iron, calcium, magnesium, manganese, zinc and selenium. Potassium in an important component of cell and body fluids that helps controlling heart rate and blood pressure. Manganese is used by the body as a co-factor for the antioxidant enzyme superoxide dismutase. Iron is required for red blood cell formation.

    §         The herb is also a rich source of many important vitamins such as B-complex group vitamins, vitamin-A, vitamin-C, niacin, thiamin and pyridoxine.

    §         Dry savory provides 1.810 mg of vitamin B-6 or pyridoxine; furnishing about 130% of RDA. Pyridoxine keeps up GABA (soothening neurotransmitter) levels in the brain which has stress buster function.

    §         Vitamin C helps body develop resistance against infectious agents and scavenge harmful, pro-inflammatory free radicals.

    §         Vitamin A is a fat soluble vitamin and antioxidant that is required maintaining healthy mucus membranes and skin and is also essential for vision. Consumption of natural fruits rich in flavonoids like vitamin A, carotenes helps protect from lung and oral cavity cancers.

    Dry savory herb has amazingly high levels of vitamins and minerals. Just 100 g of ground dry herb provides (% of Recommended daily allowance)

    120% of dietary fiber,
    25% of Niacin,
    130% of vitamin B-6 (pyridoxine),
    83% of vitamin C,
    177% of vitamin A,
    474% of iron,
    210% of calcium,
    94% magnesium,of and
    265% of manganese
    but no cholesterol.
    table below for in depth analysis of nutrients:

    Savory (Satureja hortensis), Dry, ground,
    Nutrient value per 100 g
    (Source: USDA National Nutrient data base)
    Principle
    Nutrient Value
    Percentage of RDA
    Energy
    272 Kcal
    13.5%
    Carbohydrates
    68.73 g
    53%
    Protein
    6.73 g
    12%
    Total Fat
    5.91 g
    30%
    Cholesterol
    0 mg
    0%
    Dietary Fiber
    45.7 g
    120%
    Vitamins

    Niacin
    4.080 mg
    25.5%
    Pyridoxine
    1.810 mg
    139%
    Riboflavin
    0.471 mg
    36%
    Thiamin
    0.366 mg
    30.5%
    Vitamin A
    5310 IU
    177%
    Vitamin C
    50 mg
    83%
    Electrolytes

    Sodium
    24 mg
    1.5%
    Potassium
    1051 mg
    22%
    Minerals

    Calcium
    2132 mg
    210 %
    Copper
    0.847 mg
    94%
    Iron
    37.88 mg
    474%
    Magnesium
    377 mg
    94 %
    Manganese
    6.100 mg
    265%
    Phosphorus
    140 mg
    20%
    Selenium
    4.6 mcg
    8%
    Zinc
    4.30 mg
    39%
    Medicinal uses
    §         Savory herb contains many important essential oils which are found to have anti-bacterial and anti-fungal applications.

    §         As in thyme, distilled tepid savory water is used for throat gargling to help relieve sore throat and bronchitis symptoms.

    §         The constituents in this herb parts, especially the flowering shoots, has anti-septic, carminative (anti-flatulence), digestive (helps digestion), expectorant (help clear throat), stomachic and anti-rheumatic (relieves joint pain) functions.

    §         Attributed Medicinal Properties
    While both varieties are used in cooking, Summer Savory has a much longer tradition of medicinal use.It has long been reputed to be a general tonic to the digestive tract and as a powerful antiseptic. Branches of savory were tossed onto fire to create an aromatic disinfectant. Even today, because of its pungent oils, it is commonly used in toothpaste and soaps. Active compounds of the savory leaf include volatile oils (carvacrol, p-cymene, alpha-thujene, alpha-pinene, beta-myrcene, beta-caryophyllene, terpinene, and thymol), and tannic acid. The carvacol and p-cymene content of this herb give it a mild antiseptic effect. The tannin content is responsible for savory’s astringent qualities, making it a popular choice in the relief of diarrhea. The herb has also been used as a gargle for sore throat. As a digestive aid, savory is used in cases of indigestion and flatulence. It is often added as a spice to dishes containing beans for this reason. The most common medicinal use of savory today is in the treatment of gastrointestinal enteritis, the inflammation of the intestinal tract. In some folk cultures, savory has been used to increase libido.

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    Show of the Week March 26 2012

    Milk Thistle—

    Immunostimulatory effect of Silybum Marianum (milk thistle) extract

    Review of clinical trials evaluating safety and efficacy of milk thistle

    The potential of milk thistle

    Milk thistle in liver diseases- past, present, future

    Recipe for Milk Thistle Usage

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    Immunostimulatory effect of Silybum Marianum (milk thistle) extract.

    Wilasrusmee C, Kittur S, Shah G, Siddiqui J, Bruch D, Wilasrusmee S, Kittur DS.

    Source–Department of Surgery SUNY Upstate Medical University, Syracuse, New York 13210, USA. kitturd@upstate.edu

    BACKGROUND–Herbal products are increasingly used for their effects on the immune system. Milk Thistle, a commonly used herbal product is known to inhibit growth of certain tumors, although the mechanism of this effect remains unknown. Previously we have shown that Milk Thistle extracts stimulate neurons in culture. Since other drugs that affect the neuronal; system also affect the immune system, we investigated the effects of Milk Thistle on the immune system.–MATERIAL/METHODS-Standardized Milk Thistle extract was studied in murine lymphocyte proliferation tests using Concanavalin A (ConA) as mitogen for non-specific stimulation and mixed lymphocyte culture (MLC) as allospecific stimulation. Th1 and Th2 cytokine levels in MLC were assayed by two antibody capture ELISA technique. All tests were performed in triplicate and repeated twice.—RESULTS-We found that Milk Thistle is immunostimulatory in vitro. It increased lymphocyte proliferation in both mitogen and MLC assays. These effects of Milk Thistle were associated with an increase in interferon gamma, interleukin (IL)-4 and IL-10 cytokines in the MLC (table). This immunostimulatory effect increased in response to increasing doses of Milk Thistle.—CONCLUSIONS-Our study has uncovered a novel effect of milk thistle on the immune system. This immunostimulatory effect may be of benefit in increasing the immunity to infectious diseases.–PMID-12444368-[PubMed – indexed for MEDLINE]

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    Review of clinical trials evaluating safety and efficacy of milk thistle (Silybum marianum [L.] Gaertn.).

    Tamayo C, Diamond S.

    Source–Research and Development at Flora Inc, Bethesda, MD 20817, USA. ctamayo2@comcast.net

    Abstract–Milk thistle extracts have been used as traditional herbal remedies for almost 2000 years. The extracts are still widely used to protect the liver against toxins and to control chronic liver diseases. Recent experimental and clinical studies suggest that milk thistle extracts also have anticancer, antidiabetic, and cardioprotective effects. This article reviews clinical trials of milk thistle conducted in the past 5 years including pharmacokinetic and toxicity studies, herb-drug interactions, and other safety issues. Several trials have studied the effects of milk thistle for patients with liver diseases, cancer, hepatitis C, HIV, diabetes, and hypercholesterolemia. Promising results have been reported in the protective effect of milk thistle in certain types of cancer, and ongoing trials will provide more evidence about this effect. In addition, new established doses and improvement on the quality and standardization of this herb will provide the much-awaited evidence about the efficacy of milk thistle in the treatment of liver diseases. Milk thistle extracts are known to be safe and well tolerated, and toxic or adverse effects observed in the reviewed clinical trials seem to be minimal. The future of milk thistle research is promising, and high-quality randomized clinical trials on milk thistle versus placebo may be needed to further demonstrate the safety and efficacy of this herb.-PMID-17548793-[PubMed – indexed for MEDLINE]

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    The potential of milk thistle (Silybum marianum L.), an Israeli native, as a source of edible sprouts rich in antioxidants.

    Vaknin Y, Hadas R, Schafferman D, Murkhovsky L, Bashan N.

    Source–Department of Agronomy and Natural Resources, Institute of Plant Sciences, Agricultural Research Organization, Volcani Center, Bet Dagan, Israel. yiftachv@volcani.agri.gov.il

    Abstract–The potential of wild plants in Israel as sources of edible sprouts has not been investigated until now. Milk thistle (Silybum marianum L.) is native to the Mediterranean basin and is now widespread throughout the world; its young fleshy stems are traditionally eaten by the local Arab sector in Israel, and its sprouts are rich in antioxidants and have been used as a traditional medicine for diseases of the liver and biliary tract. The active extract of milk thistle, silymarin, is a mixture of flavonolignans and is a strong antioxidant that has been proved to promote liver cell regeneration, to reduce blood cholesterol and to help prevent cancer. The present objective was to investigate the potential of milk thistle as a source of edible sprouts rich in antioxidants. We found that seed germination within 3-4 days was high (96%, except for striated seeds). Exposure to light significantly reduced sprout growth and significantly increased the polyphenol content and antioxidative capacity. The polyphenol content was 30% higher in seeds originating from purple inflorescences than in those from white ones. We thus found milk thistle to be a good candidate source of healthy edible sprouts.

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    Milk thistle in liver diseases- past, present, future.

    Abenavoli L, Capasso R, Milic N, Capasso F.

    Source

    Department of Experimental and Clinical Medicine, University Magna Graecia, Catanzaro, Italy. l.abenavoli@unicz.it

    Abstract

    Silybum marianum or milk thistle (MT) is the most well-researched plant in the treatment of liver disease. The active complex of MT is a lipophilic extract from the seeds of the plant and is composed of three isomer flavonolignans (silybin, silydianin, and silychristin) collectively known as silymarin. Silybin is a component with the greatest degree of biological activity and makes up 50% to 70% of silymarin. Silymarin is found in the entire plant but it is concentrated in the fruit and seeds. Silymarin acts as an antioxidant by reducing free radical production and lipid peroxidation, has antifibrotic activity and may act as a toxin blockade agent by inhibiting binding of toxins to the hepatocyte cell membrane receptors. In animals, silymarin reduces liver injury caused by acetaminophen, carbon tetrachloride, radiation, iron overload, phenylhydrazine, alcohol, cold ischaemia and Amanita phalloides. Silymarin has been used to treat alcoholic liver disease, acute and chronic viral hepatitis and toxin-induced liver diseases.–PMID-20564545-[PubMed – indexed for MEDLINE]

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    Recipe for Milk Thistle Usage—Take Milk thistle in seed form make a tea with it and take in conjunction with it 1000 mgs if Vitamin C and 1000mgs of MSM—this will increase the impact of the liver by increasing interferon production as welldetox the liver of harmful chemicals——If you are around solvents then you may want to add Arginine 500 mgs -1000mgs to the mix or even just add it to the milk thistle——If you have liver poisoning then add Alpha Lipoic Acid 100-200 mgs with vitamin C 1000mgs and milk thistle——For Excess Fat in the Liver you may want to increase B5  500-1000mgs and L Carnitine 500-2grams with it and the use of Taurine 500-1000mgs  and Bile Salts (as suggested on the bottle)—–For issues in the restoring and regenerating of the liver —utilizing milk thistle with sage in equal parts in water and drinking—adding things like nettle and dandelion will assist as well in the blood purifying effect as well—-Sprouting the seeds –as well and consuming them will assist as well with the antioxidant effect of the herb and may even slow down the effects of aging

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    Show of the Week March 30 2012

     

    Metalloestrogens- A New Class Of Cancer-Causing Estrogens

     

    What is Calorie Restriction (CR)?

     

    Protocols for Reducing and Regenerating Colon health—Reduction in Body Mass

     

    H. Pylori Bacteria Linked to Blood Sugar Control in Adult Type II Diabetes

     

    The Truth About Cholesterol and Saturated Fat

     

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    Metalloestrogens- A New Class Of Cancer-Causing Estrogens

    Post date:

    Sunday, March 18th 2012 at 10:00 am by Sayer Ji

    this can be a male testis as well as a female breast having these metals in our endocrine system so the genders should be aware

    Metals like aluminum have been linked to breast cancer for some time, but new research is confirming the existence of an entirely new class of cancer-causing estrogens known as “metalloestrogens,”[U1] and which are in thousands of consumer products — some which are even used in supplements and foods as “nutrients”…—-A new study published in journal Cancer Research reveals that dietary cadmium exposure increases the risk of postmenopausal breast cancer, confirming earlier research that a broad range of metals we are now being increasingly exposed to represent an emerging class of “metalloestrogens” with the potential to add to the estrogenic burden of the human breast. [U2]—In a 2006 report published in the Journal of Applied Toxicology, researchers found that the following metals were capable of binding to cellular estrogen receptors and then mimicking the actions of physiological estrogens: “aluminium, antimony, arsenite, barium, cadmium, chromium (Cr(II)), cobalt, copper, lead, mercury, nickel, selenite, tin and vanadate.”  [U3]—-As we revealed in an earlier exposé on the use of toxic forms of selenium in USDA certified organic infant formula, exposure to sodium selenite (and sodium selenate) is difficult to avoid, as it is the primary source of supplemental selenium in mass market vitamins, foods, beverages, etc. The same is true for inorganic forms of chromium, copper, nickel, tin and and vanadium, which you will find on the labels of many mass market multivitamins. –Another daily source of metalloestrogen exposure for millions of consumers is aluminum-based antiperspirants. Investigations into the link between these personal care products and breast cancer risk came to a head earlier this year in a story we broke, and excerpt from below: –Aluminium salts used as antiperspirants have been incriminated as contributing to breast cancer incidence in Western societies. To date, very little or no epidemiological or experimental data confirm or infirm this hypothesis. We report here that in MCF-10A human mammary epithelial cells, a well-established normal human mammary epithelial cell model, long-term exposure to aluminium chloride (AlCl(3) ) concentrations of 10-300 µm, i.e. up to 100 000-fold lower than those found in antiperspirants, and in the range of those recently measured in the human breast, results in loss of contact inhibition and anchorage-independent growth.” [emphasis added]–If a metal can exhibit carcinogenic properties at a concentration 100,000-fold lower than presently used in personal care products, it is critical that there be a paradigm shift in the way toxicological risk assessments are performed. –Presently, the risk assessments depend on animal studies, where the goal is to find out how much of a chemical it takes to acutely kill 50% of an exposed population (LD50). Only then, is an “acceptable level of harm” extrapolated for humans (as if determining an “acceptable level of harm” were an ethically neutral objective). ——————–The problem is that humans are not mice, there are profound synergistic toxicities that are never accounted for when we are exposed to more than one chemical simultaneously,[U4] the LD50 does not indicate what constitutes a chronic/sublethal toxic dose or an acknowledgment that chronic toxic effects do occur at far lower doses, and mostly importantly for the purpose of this article, the concept of increasing toxicity as the concentration decreases is not even considered. —This, in fact, is what happens in certain types of radiation and petrochemical exposure. Low-dose radiation may be far more carcinogenic than high-dose radiation, which is why “early detection” through x-ray mammography is such a brutally dishonest practice, as it likely causes much more cancer than it is said to prevent. –This is also what happens with certain petrochemicals, e.g. bisphenol A, benzene, pthlatates, which is to say, they may be more toxic at lower concentration than higher ones, due to their hormone-mimicking, blocking and/or intensifying effects, as well as their ability to interact on a molecular level with cell surfaces and structures, which would not be possible were they aggregated in greater volumes or quantities. The entire field of nanotechnology, in fact, suffers from this counterintuitive problem: the smaller the size, the higher the potential toxicity or the greater the unintended, adverse health effects.——The problem of aluminum and similar metallogestrogen exposure, however, is greater than simply reforming manufacturers and consumer products. The military releases at least 500 tons of aluminum chaff annually during training within selected military operating areas in the United States, and only clandestine organizations know how much metal has been released into the environment in the name of “saving the earth” through “geoengineering.” Indeed, in what is known as Atmospheric Aerosol Spraying, our environment has increasingly become saturated through with metal pollution. The problem has become so bad that biotech corporations have begun engineering aluminum-resistant plants[U5], since many soils have become too acidified due to metal contamination to adequately sustain plants that produce food.

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    What is Calorie Restriction (CR)?

    The goal of Calorie Restriction is to achieve a longer and healthier life by

    eating fewer calories
    consuming adequate vitamins, minerals, and other essential nutrients
    Extensive scientific research has shown that a CR diet improves the health and extends the lifespan of every species so far tested, including worms, spiders, rodents, dogs, cows and monkeys. We believe that people who adopt a CR diet will see the same results longer life and better health.

    Getting  Started

    Simply eating less may not improve health or extend lifespan – it can lead to malnutrition.

    Replace calorie-dense foods with calorie-sparse, nutrient-dense foods

    Before worrying about how many calories you’re eating, make sure that the foods in your diet provide sufficient nutrition to avoid malnutrition once you begin to restrict them.

    Avoid simple sugars and flours.
    Sugars and flours generally contain very little nutrition for their calorie content. They also have high glycemic indices, which means that your body absorbs them quickly, leaving you wanting more a short time later.
    Eat both green leafy (salad) and other vegetables.
    Vegetables — both green leafy vegetables and non-leaf vegetables — contain the highest content of a wide variety of nutrients for their calorie content. By volume (and often by calories), vegetables are the major component of many calorie restricted but not nutrient deficient diets.
    Carefully select your protein and fat sources.
    Both protein and fat are required macronutrients, but their form can have a significant influence on a person’s risk factors for a wide variety of diseases.
    Make sure your protein intake is sufficient, but not overly abundant.
    Common recommendations for total protein intake range from 0.6 to 0.8 grams per kilogram of body weight, and some recommendations are much higher. This is probably a minimum.—another easier way to figure this out is to take either 60% of body weight or 80 % and multiply it by your weight this will give a close approximation of the amount of protein you should have—an example would be say a 110 lb person minimal amount would be 66grams a day and up to 88gams a day—take the .6 X 110=66— take .8 X110=88—or multiply the 60% X110 and remove the zero’s—again gives you 66 same with the 80% X 110 = 88—remove the zeros—will give a good approximation
    Make sure your proteins are complete and balanced.
    A complete protein contains all the essential amino acids, while a balanced protein contains all those amino acids in ratios that are most useful to human biophysiology.Most animal proteins are complete and well-balanced
    There are very few perfectly balanced proteins in our food supply, but animal proteins tend to be among the most balanced. Unfortunately, animal proteins also tend to include undesirable components. For example, red meat is carcinogenic [PMID: 12376502], and meat (especially red meat) and dairy often contain large quantities of saturated fats. The nutrient density (as always, on a per-calorie basis) of meats is often lower than other choices.—Again this is outdated badly—red meats should be broiled or cooked thoroughly after cleaned—but not to subsist on red meat totally which can be unhealthy—there are other animal proteins that are easier to consume and digest—this would be easier and more efficient for most
    Non-animal proteins can be balanced by combining different food families
    One can get extremely detailed in finding “complementary” foods, but in general, combining legumes (beans) or seeds or nuts in balance– will yield a balanced protein, and rice protein can complement the proteins in vegetables like broccoli, cauliflower, or spinach. Be aware, however, that both rice and grains (even whole grains) have relatively high glycemic indices and relatively low nutrient densities. If you’re going to consume these, choose Cassava or Some other form or Starch where potassium or other nutrients can be uptaken properly
    Comment here this information is outdated badly due to the GMO and GE contamination You may want to reconsider  these foods especially the rice an legumes which are high in starch ( sugars) and will turn to fat—-if consuming to act as a cleanse fashion then it would be best to utilize the fibres from other foods such as fruits and veges—most rice today is GMO’d and should be avoided
    Select Healthy fats, and consume some Omega-3 fats
    Foods containing monounsaturated fats include olive oil, almonds, hazelnuts, and avocados. Most of your fat intake should be from these foods. A very small amount of fat should be in the form of Omega-3 fatty acids, which are found in fatty fish (e.g. salmon) –                ( minimize fish oils due to the mercury loads in these fish ) and flax oil, walnut oil, and perilla. Caution- fatty foods, even healthy choices, are high in calories so be sure that you carefully track your intake so as to stay within your Calorie goal.—
    Get baseline blood tests done

    In order to chart your progress, and to make sure that you are avoiding nutrient deficiencies and other hazards, get at least the minimal recommended blood tests done. You’ll want to know these results from before your calorie-restricted diet begins, so that you’ll have a baseline for comparison as you move into a calorie-restricted diet.

    Reduce calories after improving diet quality (i.e. nutrition)

    Once your diet consists primarily of nutrient-dense, calorie-sparse foods, you can safely begin to reduce your total calorie intake. There are some things to consider at this point, if you have not already considered them.

    Lose weight slowly—-Many people lose weight simply by changing their diet to include more calorie-sparse foods. Even this weight loss should not be allowed to happen too quickly, but by the time you’re able to restrict calories, your weight loss should proceed very slowly. There are two reasons for this:

    Pesticides and other toxins are fat soluble.
    There are many pesticides and other toxins in our food supply that are fat soluble. Human bodies store these toxins relatively harmlessly in body fat. If you lose that fat too quickly, however, all these toxins are flushed into your bloodstream, and your detoxification mechanisms (i.e., your kidney and liver) are unable to remove them [B120YD, 78-80]. You may thus wind up with much higher blood toxin levels than what people are normally subjected to, which may have any number of life-shortening effects.
    Sudden adult onset Calorie Restriction shortens the lifespans of mice.—Though the lifespan enhancing effects of calorie restriction have been known since the 1930s, it was also known that if adult mice were suddenly put on a calorie restricted diet, their lifespans were actually shortened. Dr. Walford found in the 1980s, however, that if mice were slowly transitioned from an ad lib to a calorie restricted diet, then their lifespans increased. The time for this transition recommended by Dr. Walford is a minimum of 6 to 9 months, but preferably 1 to 2 years. [p. 78, BY120YD]
    Be aware of the potential risks in CR dieting!

    Any significant dietary change should be done in consultation with a knowledgeable physician. There are several other risks that you should be aware of.

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    Protocols for Reducing and Regenerating Colon health—Reduction in Body Mass

     

    There are things needed to be applied In the area of reduction—and with reduction of body mass, there will be a reduction to the amount of poisons, toxins, build up and inflammation—So when applying these protocols do them at least once a month at any time of the month and watch unwanted health conditions disappear—and a new vigor come back.

     

    Here is the NO list: NO : Bread(s) or any Facsimile of bread( crackers donuts, tacos, pita, breads ) – Pasta –Rice –Corn – Cereal ( not even oatmeal during this time ) Grains in general—No Stores bought Juices,-No Pop ( Soda for the easterners ) No Milk or Dairy Products that are Sugar or Fat Free—No Sugar (Brown or White or Pasteurized Honey- Agave Syrup ) Molasses-NO MICROWAVE ( not to be used any time—totally Damages the Body from cellular level to tissues and DNA damaging ) Margarine-Canola Oil – Vegetable Oil – Soybean oil ( or any Soy whatsoever or any Derivatives – TVP –HVP – AVP –HPP – MSG –Disodium Guanylate – Disodium Inosinate-Bananas – Grapes – Raisons – Watermelon—Dates-Pork or Pork Byproducts ( sausauges, bacon, hot dogs, pork rinds etc)

     

    Here is the YES List: Yes to -Meat – Poultry –Fish –Lamb – Eggs – Yogurt ( Plain and with Fat ) Kefir ( plain and with Fat ) Whey Protein – Gelatin Broths ( Plain or Vanilla Without Artificial Sweetners –Aspartame—Splenda – Aceslfame Potassium ) Cottage Cheese ( unless you have a yeast or fungal infection ) Cream – Olive oil – Butter –  Ghee – Almond Oil – Pumpkin Seed Oil – Macadamian Nut Oil – Apricot oil – Sesame Seed Oil – Coconut Oil-  Palm Oil – Animal Fat ( try to make sure the animals are GRASS FED not GRAIN FED—the fat then will be beneficial if the fat is from a grass Fed Animal ) Fruit with Fibre ( Apple, Peaches, Plums, Pears, Apricot, Nectarines etc PEEL BEFORE CONSUMING TO MINIMIZE PESTICIDE OR WAXES even if organic)Citrus Fruits – Oranges – Lemons – Pommelo’s – Grapefruit – Tangerines- Mannelos, etc Berries ( Wash and clean with either Peroxide. GSE, Vinegar, Lemon Juice- Use an Iodine Spray ) Veggies all kinds (Wash and clean with either Peroxide. GSE, Vinegar, Lemon Juice- Use an Iodine Spray ) Make Juice fresh and Home made Use Sprouts—Seeds  – Nuts – Make Nut or Seed butters—

    Do this for 5-10 days and afterwards if you wish to consume rice or pasta or polenta then introduce them back slow and minimize the consumption—breads if you consume then utilize Rye, Barley, or Oat and again Minimally—the idea is to get off breads and cereals which are actually Fermenting inside and potentially causing DNA damage and Restructuring— Potato Can be used as long as it is not fried—Can be used if -broiled—boiled—mashed-or baked this will assist in the cleansing of the colon as well as provide energy

     

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    H. Pylori Bacteria Linked to Blood Sugar Control in Adult Type II Diabetes

     

    A new study by researchers at NYU Langone Medical Center reveals that the presence of Helicobacter pylori (H. pylori) bacteria is associated with elevated levels of glycosylated hemoglobin (HbA1c), an important biomarker for blood glucose levels and diabetes.)—ScienceDaily (Mar. 14, 2012) — A new study by researchers at NYU Langone Medical Center reveals that the presence of Helicobacter pylori (H. pylori) bacteria is associated with elevated levels of glycosylated hemoglobin (HbA1c), an important biomarker for blood glucose levels and diabetes. The association was even stronger in obese individuals with a higher Body Mass Index (BMI).—The results, which suggest the bacteria may play a role in the development of diabetes in adults, are available online in The Journal of Infectious Diseases.—There have been several studies evaluating the effect of the presence of H. pylori on diabetes outcomes, but this is the first to examine the effect on HbA1c, an important, objective biomarker for long-term blood sugar levels, explained Yu Chen, PhD, MPH, associate professor of epidemiology at NYU School of Medicine, part of NYU Langone Medical Center. “The prevalence of obesity and diabetes is growing at a rapid rate, so the more we know about what factors impact these conditions, the better chance we have for doing something about it,” Dr. Chen said. Looking at the effects of H. pylori on HbA1c, and whether the association differs according to BMI status, provided what could be a key piece of information for future treatment of diabetes, she explained.—Type II diabetes causes an estimated 3.8 million adult deaths globally. There have been conflicting reports about the association between H. pylori infection and type II diabetes. To better understand the relationship between H. pylori and the disease, Dr. Chen and Martin J. Blaser, MD, the Frederick H. King Professor of Internal Medicine and professor of microbiology, analyzed data from participants in two National Health and Nutrition Surveys (NHANES III and NHANES 1999-2000) to assess the association between H. pylori and levels of HbA1c.—-“Obesity is an established risk factor for diabetes and it is known that high BMI is associated with elevated HbA1c. Separately, the presence of H. pylori is also associated with elevated HbA1c,” said Dr. Blaser, who has studied the bacteria for more than 20 years. “We hypothesized that having both high BMI and the presence of H. pylori would have a synergistic effect, increasing HbA1c even more than the sum of the individual effect of either risk factor alone. We now know that this is true.”—-H. pylori lives in the mucous layer lining the stomach where it persists for decades. It is acquired usually before the age of 10, and is transmitted mainly in families. Dr. Blaser’s previous studies have confirmed the bacterium’s link to stomach cancer and elucidated genes associated with its virulence, particularly a gene called cagA.

    Regarding H. pylori’s association with elevated HbA1c, Drs. Chen and Blaser believe the bacterium may affect the levels of two stomach hormones that help regulate blood glucose, and they suggest that eradicating H. pylori using antibiotics in some older obese individuals could be beneficial.—More research will be needed to evaluate the health effects of H. pylori and its eradication among different age groups and in relation to obesity status, the authors noted.”If future studies confirm our finding, it may be beneficial for individuals at risk for diabetes to be tested for the presence of H. pylori and, depending on the individual’s risk factor profile” Dr. Chen.—–In an accompanying editorial in The Journal of Infectious Diseases, Dani Cohen, PhD, of Tel Aviv University in Israel, pointed out that while previous studies have addressed the association between type II diabetes and H. pylori in small samples, this study analyzed two independent large national samples of the general population. Dr. Cohen agreed with the study authors, suggesting that adults infected with H. pylori with higher BMI levels, even if asymptomatic, may need anti-H. pylori therapy to control or prevent type II diabetes. If the study findings are confirmed, Dr. Cohen wrote, they “could have important clinical and public health implications.”–Story Source-The above story is reprinted from materials provided by NYU Langone Medical Center, via Newswise.
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    The Truth About Cholesterol and Saturated Fat

     

    TOP  H

     

    [U1]Chemtrail fallout has Over 28 components and one of them is aluminum not to mention managese and barium and uranium and thorium

    [U2]Not Just the breast—the whole endocrine system
    [U3]Some of these are in the chemtrails
    [U4]Again—take the 28 components of chemtrails—add that to the water you drink if you are still drinking from the tap—then figire out the levels in your plants ( organic or otherwise since they will uptake the toxic metals as well from the ground released by the pesticides and chemtrails) and you now have a chemical mix killing or debilitating a human being
    [U5]Which will further increase the levels in our system since these plants will be able to absorb more of the metal —it makes them more resistant –not more healthy—big difference

    #349
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    Keymaster

    Iodine Uses in the Old days!!

    —Iodine has been around for centuries and some of the uses of Iodine have been Lost—Til NOW!!! Here are some uses for iodine—Curing Syphilis—Curing Epilepsy-Syphiloma Of the Nervous System-Syhpilitc infections Of the Brain-Neurolgia-Nocturnal Pain In the Head—for Syhplitic infection of the brain they used 10 grains or 1 drahm several times a day and would saturate ( Called Iodism ) the person in iodine —it was the most effective way to C-U-R-E the issue- ( 10 grains is 647 miligrams -1 drahm – 1,772 mgs orrrrr 1.77 grams of iodine ) We are talking here therapeutic dosing to C-U-R-E a infection—the Same could be Used for Syphilitic Paraplegia (is an impairment in motor or sensory function of the lower extremities as a result of a syphilis infection ) the same application can be applied and should be applies as [previous for the brain—there has to be a saturation in the use to clear it up—Malarial Fevers—Cures it—again would be in the dose-Usually for 2-3 days and then restored- the dose is 1 ml ( 16 minims) in water – 3 times a day before meals ( lugols or Iodoral) typhoid fever a solution (1 ml ( 16 minims) in water- is administered 3 times daily to reduce fever –and diarrhea-Lumbago-Sciatica-and Rheumatoid ( Chronic) are all treated with Iodine ( or Iodides ) the causes of these issues are tin –mercury-copper or lead or syphilis-and iodine treats them all—the remedy was 15 grains ( 970 mgs) to a drachm ( 1/8 of an ounce or 3.96 mils)—4 times a day 1 ml –The way it works is that it breaks down the elements and makes them soluble so that your kidneys can excrete them out of you— Saturation of iodine will clear Psoriasis—Application Topically would be around the neck –inner and outer Pectoral region by application of a sponge or paint brush—and to repeat this process daily for 3-5 days– to remove Pleuritic issues and other respiratory ailments like pneumonia you can make a topical by applying it in a mixture of petroleum jelly—or coconut oil or other fats and apply it topically as well—women with breast issues of lumps or potential cancers would be advised to paint the breast or apply the topically inside and on the sides—for prostate cancers or inflammation —utilze the iodine and apply with either DMSO or Turpentine and or a gelly mix or paint the area–And just think they knew this in the 1890’s—and today—we cannot cure what they could then—just goes to show you—being certified does not make you qualified—

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    More Benefits Of Iodine

    IODINE–Iodine is utilized by every hormone receptor in the body. The absence of iodine causes a hormonal dysfunction that can be seen with practically every hormone inside the body. Dr. Flechas has recently been able to show that patients with insulin resistant diabetes have a partial to full remission of their illness in the presence of taking iodine. Iodine deficiency is also felt to be the source of ovarian cysts. With iodine replacement therapy the cysts disappear and women have stopped having ovarian cysts.”–

    All cells in the body need iodine for proper functioning. All glands (thyroid, adrenal, etc.) especially need iodine for the production of hormones. Dr. There is Evidence that iodine deficiency is a major cause of breast cancer and other diseases of the reproductive organs such as ovarian, uterus and prostrate cysts and cancers. Iodine levels in US soil have fallen 50 per cent over the past 50 years and soil in the US is deficient in iodine. The Great Lakes region has some of lowest soil iodine levels in the world and this results in high levels of cancers related to iodine deficiency. There has been a success in treating fibrocystic breast disease (cysts in the breast) with iodine/iodine supplementation. In one case a 37 year-old woman with severe fibrocystic breast disease was completely cured after supplementing with 50 mgs of iodine a day for two months. Women with large breasts need more iodine than women with smaller breasts. Other medical authorities agree that iodine deficiency can lead to fibrocystic breast disease and/or ovarian cysts Iodine can similarly reduce uterine fibroids and one of the first conventional medical treatments for severe fibroids was to paint the uterus with iodine. [4] Some other medical conditions associated with iodine deficiency are goiters, Graves’ Disease, Hashimoto’s Disease, fatigue and impaired immune system function. Iodine deficiency during pregnancy can lead to miscarriages and reduced IQ in surviving offspring. The World Health Organization says that iodine deficiency is the largest single cause of mental retardation. Iodine also detoxifies the body by removing mercury, fluorides, chlorides, and bromides.

    IODINE BENEFITS

    “If you think you may be deficient in Iodine, consider this; most of the US population has one or more mercury amalgam fillings in their mouths. A consequence of this is that minute amounts of the heavy metal mercury are continuously being released into the mouth and absorbed into the body. This toxication stimulates a natural detox reaction by the body. Several mechanisms are utilized to remove the mercury. In order for these detoxification mechanisms to work properly, numerous essential minerals are utilized. Iodine, Zinc, Sulfur, Selenium, and Silica stimulate the excretion of heavy metals including mercury. Iodine is at the top of the list when it comes to mercury removal.

    “Unfortunately, the average persons daily intake of Iodine is not high enough to keep them mercury free even when not exposed to excessive levels. Add on the exposure of mercury from vaccinations, smoking, etc., and you have the potential for serious heavy metal toxicity. This toxicity can manifest itself in many ways causing problems that would not normally be attributed to high levels of mercury.

    “Iodine is essential for the health of the: Thyroid, Breast and Prostate.

    “Iodine chelates:

    · Mercury

    · Lead

    · Cadmium

    · Aluminum

    · Bromide

    · Tin

    “Iodine helps to improve-or C-U-R-E

    · Bowel irregularity

    · Brain fog

    · Renaud’s syndrome (numb finger tips)

    · Low energy

    · Sensitivity to cold

    · Skin complexion

    · Reduction of Prostate Hypertrophy

    · Pneumonia

    · Pleurisy

    · Syphlis of the Bone

    · Ulcerative Syphlis

    · Psoriasis

    · Rheumatoid Joint issues

    · Fights small pox lesions

     

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    New Way to Abate Heart Attacks Before Patients Get to the Hospital

    ScienceDaily (Mar. 27, 2012) — Paramedics can reduce someone’s chances of having a cardiac arrest or dying by 50 percent by immediately administering a mixture of glucose, insulin and potassium (“GIK”) to people having a heart attack, according to research presented March 27 at the American College of Cardiology’s 61st Annual Scientific Session. –The study showed that patients who received GIK immediately after being diagnosed with acute coronary syndrome — which indicates a heart attack is either in progress or on the way — were 50 percent less likely to have cardiac arrest (a condition in which the heart suddenly stops beating) or die than those who received a placebo, although the treatment did not prevent the heart attack from occurring. Over the first month following the event, patients who received GIK were 40 percent less likely to have cardiac arrest, die or be hospitalized for heart failure.—The effect was even more striking for patients with ST-elevation heart attacks, which require immediate treatment. For those patients, immediate GIK was associated with a 60 percent reduction in cardiac arrest or death.—“When started immediately in the home or on the way to the hospital — even before the diagnosis is completely established — GIK appears to reduce the size of heart attacks and to reduce by half the risk of having a cardiac arrest or dying,” said Harry P. Selker, MD, MSPH, executive director of the Institute for Clinical Research and Health Policy Studies at Tufts Medical Center, who led the study with Joni Beshansky, RN, MPH, co-principal investigator and project director. “Acute coronary syndromes represent the largest cause of death in this country. GIK is a very inexpensive treatment that appears to have promise in reducing those deaths and morbidity.”——–The cost of the treatment is about $50.—“Because the trial is the first to show GIK is effective when used by paramedics in real-world community settings, it could have important implications for the treatment of heart attacks,” Dr. Selker said. Previous clinical trials have shown no consistent effect, likely because the GIK was given too late to help. This study, the “IMMEDIATE Trial,” was the first to test the effectiveness of administering GIK at the very first signs of a threatening heart attack, in the community, rather than waiting hours until the diagnosis was well-established at a hospital, as done in previous clinical trials.—“We wanted to do something that is effective and can be used anywhere,” said Dr. Selker. “We’ve done a lot of studies of acute cardiac care in emergency departments and hospitals, but more people die of heart attacks outside the hospital than inside the hospital. Hundreds of thousands of people per year are dying out in the community; we wanted to direct our attention to those patients.”—The researchers trained paramedics in 36 Emergency Medical Services systems in 13 cities across the country to administer GIK after determining that a patient was likely having a threatened or already established heart attack using electrocardiograph-based ACI-TIPI (acute cardiac ischemia time-insensitive predictive instrument) and thrombolytic predictive instrument decision support that prints patient-specific predictions on the top of an electrocardiogram. The paramedics used these predictions to decide if a patient would likely benefit from treatment. There were 911 patients randomized to receive either the GIK treatment or a placebo.—Administering GIK immediately also reduced the severity of the damage to the heart tissue from the heart attack. On average, 2 percent of the heart tissue was destroyed by the heart attack in people receiving GIK, compared with 10 percent in those who received the placebo. Although a significant proportion of suspected heart attacks are later determined to be false alarms (23 percent in this study), administering GIK does not appear to cause any harmful effects in such patients.The research team will follow up with study participants at six and 12 months to evaluate the longer-term benefit of the GIK treatment.–This study was funded by the NIH’s National Heart, Lung and Blood Institute.–Story Source-The above story is reprinted from materials provided by American College of Cardiology. –

    Recipe For your Own Heart Remedial—take Glycerin ( Palm or Coconut—avoid the Soy) take 1 tsp of this—add ¼ tsp of Potassium chloride or potassium Citrate-and ¼ tsp of magnesium citrate or magnesium malate ( malic acid )—mix well and use half a tsp—can be used as well as a supplement or preventative

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    Effects of lime juice on malaria parasite clearance.

    Phytother Res. 2011 Oct;25(10):1547-50

    Authors: Adegoke SA, Oyelami OA, Olatunya OS, Adeyemi LA

    Abstract
    One hundred and twenty children with acute uncomplicated malaria who were managed at the children’s outpatient department of the Wesley Guild Hospital, Ilesa (a unit of Obafemi Awolowo University Teaching Hospitals’ Complex, Ile-Ife, Osun state, Nigeria) were recruited into the study to determine the effects of lime juice on malaria parasite clearance. These children were randomized into treatment with World Health Organization recommended antimalarials (artemisinin combination therapy, ACT) either alone or with lime juice. Nine of them were lost to follow-up, four were in the group that were managed with ACT and lime, and five in the group that were managed on ACT alone. The average (SD) time to achieve >75% reduction in parasite load was significantly lower in patients on ACT and lime; 30.5 ± 2.4 h against 38.6 ± 3.3 h for those on ACT alone (p < 0.001). Also, while a significantly higher proportion of children on antimalarial drugs and lime juice achieved complete parasite clearance by 72 h of therapy (p = 0.007), ten (18.2%) patients without lime had early treatment failure (p = 0.003). There were no side effects with the use of lime juice. It may therefore be inferred, from this preliminary work, that lime juice when used with the appropriate antimalarial may enhance malaria parasite clearance especially in those with uncomplicated malaria.—PMID: 21413089 [PubMed – indexed for MEDLINE]

    Recipe For an antimalarial tea—Add wormwood1/2 and oz clove1/2 tsp and black walnut ½ oz together and brew into a pot of tea and boil this down to about half way down the pot—-when cooled strain and add to glass container—-when consuming this go ½ tsp increments and add limejuice to it or drink seperate

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    The choice of thujone as drug for diabetes. Sage and Wormwood

    Nat Prod Res. 2011 Dec;25(20):1890-2-Authors: Lachenmeier DW, Walch SG

    Abstract
    The use of thujone, a monoterpene ketone often present in sage (Salvia officinalis L.) or wormwood (Artemisia absinthium L.), for the treatment of diabetes mellitus was recently suggested in a study published in this journal. Evidence was based on the findings obtained in a diabetic rat model. After oral treatment with thujone (5 mg/kg bodyweight (bw)/day for 28 days), the cholesterol and triglyceride levels were significantly adjusted to normal levels when compared to diabetic, untreated rats. While these results sound promising and worthy of further investigation, the well-defined profile of the adverse properties of thujone demands a cautious interpretation of these results. The therapeutic margin of thujone appears to be small, as a dose-related incidence of seizures was noted in 2-year National Toxicology Program studies in rats and mice. The dose level in the diabetic rat study is also considerably higher than a daily intake that is acceptable for humans (0.1 mg/kg bw/day).–PMID: 21988529 [PubMed – indexed for MEDLINE]

    Special Note —to make this effective you would take smaller doses for a period of time and adjust the consumption of foods that would elevate the tryglcerides ( Grains and starch)

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    Show of the Week 4-06 2012

     

    Use It or Lose It- Mind Games Help Healthy Older People Too

    Brain Training Can Help Improve Specific Abilities in Older People

    Reversal effects of traditional Chinese herbs on multidrug resistance in cancer cells

    Anti-oxidant, anti-glycant, and inhibitory activity against α-amylase and α-glucosidase of selected spices and culinary herbs

    Antinociceptive, anti-inflammatory effects and acute toxicity of aqueous and ethanolic extracts of Myrtus communis

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    Use It or Lose It- Mind Games Help Healthy Older People Too

    ScienceDaily (Mar. 27, 2012) — Cognitive training including puzzles, handicrafts and life skills are known to reduce the risk, and help slow down the progress, of dementia amongst the elderly. A new study published in BioMed Central’s open access journal BMC Medicine showed that cognitive training was able to improve reasoning, memory, language and hand eye co-ordination of healthy, older adults.—It is estimated that by 2050 the number of people over 65 years old will have increased to 1.1 billion worldwide, and that 37 million of these will suffer from dementia. Research has already shown that mental activity can reduce a person’s risk of dementia but the effect of mental training on healthy people is less well understood. To address this researchers from China have investigated the use of cognitive training as a defence against mental decline for healthy older adults who live independently.—To be recruited onto the trial participants had to be between 65 and 75 years old, and have good enough eyesight, hearing, and communication skills, to be able to complete all parts of the training. The hour long training sessions occurred twice a week, for 12 weeks, and the subjects were provided with homework. Training included a multi-approach system tackling memory, reasoning, problem solving, map reading, handicrafts, health education and exercise, or focussing on reasoning only. The effect of booster training, provided six months later, was also tested.–The results of the study were positive. Profs Chunbo Li and Wenyuan Wu who led the research explained, “Compared to the control group, who received no training, both levels of cognitive training improved mental ability, although the multifaceted training had more of a long term effect. The more detailed training also improved memory, even when measured a year later and booster training had an additional improvement on mental ability scores.”—This study shows that cognitive training therapy may prevent mental decline amongst healthy older people and help them to continue independent living longer in their advancing years.—Story Source-The above story is reprinted from materials provided by BioMed Central. –Journal Reference–Yan Cheng, Wenyuan Wu, Wei Feng, Jiaqi Wang, You Chen, Yuan Shen, Qingwei Li, Xu Zhang, Chunbo Li. The effects of multi-domain versus single-domain cognitive training in non-demented older people: a randomized controlled trial. BMC Medicine, 2012; 10 (1): 30 DOI: 10.1186/1741-7015-10-30

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    Brain Training Can Help Improve Specific Abilities in Older People

    ScienceDaily (Dec. 23, 2009) — Many brain training products claim to be able to keep us mentally fit. Some products even claim that brain training can prevent dementia in old age. But there is no scientific proof that games or other brain exercises can have this effect. That is what the German Institute for Quality and Efficiency in Health Care (IQWiG) has discovered.

    Brain training can lead to an improvement, but only in the specific ability it is aimed at —As we get older our thinking gets slower and it is harder for us to learn new things. Many people try to stay mentally fit by, for example, learning a new language or doing crossword puzzles. Computer games that aim to keep the brain active are also becoming increasingly popular. “Doing exercises like trying to find symbols on a computer screen as fast as possible can actually improve your reaction time,” explains Professor Peter Sawicki, the Institute’s Director. “But scientific studies have shown that brain training only leads to an improvement in the specific ability that it is aimed at. So if you learn to find symbols quickly, it does not mean that you will be able to remember names better too.”————There is no need for people to push themselves to do brain training if they do not enjoy it —Research has not shown that brain training can keep up or enhance people’s overall mental abilities. “So there is no need to feel bad if you do not enjoy brain training: there are no health reasons for doing it,” says Sawicki. “But if you think brain training exercises are fun, you can try out different things. For example, completing sequences of letters can improve your logic skills. And practising word association techniques can help you to remember things better.”—Story Source-The above story is reprinted from materials provided by Institute for Quality and Efficiency in Health Care. Journal Reference–PAPP et al. Immediate and delayed effects of cognitive interventions in healthy elderly: A review of current literature and future directions. Alzheimer’s and Dementia, 2009; 5 (1): 50 DOI: 10.1016/j.jalz.2008.10.008

    Recipe for the brain—Utilizing Games Such as Soltaire can assist the person to have a Multi purpose activity for the brain as well as doing multi dimensional puzzles—Problem Solving –Researching topics of interest—and allowing for calm and peace of mind—

    Nootropics that can assist —Using Egg yolks—Sunflower Lecithin-Black Coffee-Tea- Black or Green—Using Spices Like Nutmeg- Rosemary-Sage-Thyme-Bay leaf—Consuming Salt ( sea salt or one mineralized without contaminants-things such as these to nourish the brain

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    Reversal effects of traditional Chinese herbs on multidrug resistance in cancer cells.

    Nat Prod Res. 2011 Nov;25(19):1885-9–Authors: Yang L, Wei DD, Chen Z, Wang JS, Kong LY

    Abstract
    Multidrug resistance (MDR) continues to be a major obstacle for successful anticancer therapy. In this work, fractions from 17 clinically used antitumour traditional Chinese medicinal herbs were tested for their potential to restore the sensitivity of MCF-7/ADR and A549/Taxol cells to a known antineoplastic agent. The effects of these fractions were evaluated by MTT method and an assay of the cellular accumulation of doxorubicin. Fractions from the PB group (herbs with the ability to promote blood circulation and remove blood stasis) showed more significant effects than fractions from the CH group (herbs with the ability to clear away heat and toxic materials). Fractions from CH₂Cl₂ extracts were more effective than fractions from EtOAc extracts. Five herbs (Curcuma wenyujin, Chrysanthemum indicum, Salvia chinensis, Ligusticum chuanxiong Hort. and Cassia tora L.) could sensitise these resistant cancer cells at a non-toxic concentration (10 µg mL⁻¹), and markedly increased doxorubicin accumulation in MCF-7/ADR cells, which necessitates further investigations on the active ingredients of these herbs and their underlying mechanisms.—PMID: 21848372 [PubMed – indexed for MEDLINE]—

    Recipe for that Tough Cancer-Here is a Tea that you can make by Utilizing Chrysanthenum-Chinese Sage- Tumeric- Senna Leaves-Ligusticum chuanxiong Hort. Take in equal parts and reduce the senna by half and make a 1 quart container of water —and drink 1-3 cups a day

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    Anti-oxidant, anti-glycant, and inhibitory activity against α-amylase and α-glucosidase of selected spices and culinary herbs.

    Cazzola R, Camerotto C, Cestaro B.

    Source-Department of Clinical Sciences L. Sacco, Faculty of Medicine and Surgery, University of Milan, Milan, Italy. roberta.cazzola@unimi.it

    Abstract—Aqueous and methanol extracts of dry sage, rosemary, basil, parsley, chili, garlic and onion were analyzed to investigate their anti-oxidant and anti-glycant activities and in vitro inhibitory potential against enzymes involved in glycemic regulation. The aqueous extracts of rosemary and sage were the richest in phenolic compounds and showed the highest ability in binding iron and inhibiting DPPH, superoxide radicals and advanced glycation end-product production, lipid peroxidation, and the activity of α-glucosidase and α-amylase. On the other hand, the methanol extracts of both these Labiatae were less efficient than those of garlic, onion, parsley and chili in scavenging hydroxyl radicals. As far as protein glycation is concerned, methanol extracts were more effective in inhibiting the production of Amadori compounds and the aqueous ones in preventing advanced glycation end-product formation. Therefore these spices may be preventive not only against cardiovascular diseases but also type 2 diabetes.

    Solution- Make sure you have a sage and rosemary teas to prevent the onset of any kind of glycation and if it is advanced then utilize the extracts in alcohol as well as consume the foods such as parlsey –onion and garlic and caynenne on a regular bases—this will reduce both ferrous peroxyls ( damge from iron and peroxide in the body ) and reduce any sugar binding protein damage that occurs–the Elimination of Glycate forming foods or Sugars will be important and as you reduce and consume the teas or foods with these things you will find te sugar “cravings” or addicition reduce dramatically

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    Antinociceptive, anti-inflammatory effects and acute toxicity of aqueous and ethanolic extracts of Myrtus communis L. Aerial parts in mice.

    J Acupunct Meridian Stud. 2011 Dec;4(4):242-7–Authors: Hosseinzadeh H, Khoshdel M, Ghorbani M

    Abstract
    Myrtus communis L ( Myrtle ). aerial parts have been used in traditional medicine for the treatment of inflammatory disease. In this study 350 mice were divided into three main groups: negative (saline), positive (morphine or diclofenac) controls, and test groups. The acute toxicity was assessed for 2 days. Antinociceptive activity was performed using hot plate and writhing tests. The anti-inflammatory effect was investigated using xylene-induced ear edema and a cotton pellet test. According to phytochemical screening, the extracts contained tannins, alkaloids, and flavonoids. The LD50 values of the aqueous and ethanolic extracts were 0.473 and 0.79 g/kg, respectively. In hot plate test, the aqueous and ethanolic extracts showed significant antinociceptive activity that was inhibited by naloxone. The extracts exhibited antinociceptive activity against acetic acid-induced writhing and also showed significant activity against acute inflammation which was dose dependent for aqueous extract. The ethanolic (0.05 g/kg) and aqueous extracts (0.005, 0.015, and 0.03 g/kg) demonstrated anti-inflammatory effects against chronic inflammation. The aqueous and ethanolic extracts of the aerial parts of M communis L. showed antinociceptive effects and these may be mediated by opioid receptors.—PMID: 22196507 [PubMed – indexed for MEDLINE]

    Recipe for Myrtle Tea—Take some leaves of Myrtle and add to a 2 cup pot and simmer for 10 minutes and drink orr add ¼ cup of the leaf and add ½ cup of Vodka or any other clear based Alcohol that is consumable ( ethanol) and blend for 10 minutes at high speed together—strain and add to glass bottle

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    Show of the Week April 9-2012

    Pediculicides—Lice and Pest treatments

    The Corporate Corruption of Organics
    Government take over of Children with Parental Consent

    Vaccinating Without Parental Knowledge Soon To Become The Norm Across The World

    U.K Doctors have reported that girls aged just 12 and 13 have suffered paralysis, convulsions and sight problems after being given the HPV vaccine.

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    Pediculicides—Lice and Pest treatments
    Chemical treatments- Today, insecticides used for the treatment of head lice include organochlorines (lindane), organophosphates (malathion), carbamates (carbaryl), pyrethrins (pyrethrum), and pyrethroids (permethrin, phenothrin, bio-allethrin).
    The only agents approved by the FDA for treatment of pediculosis are lindane and malathion.[2]

    Laboratory and clinical studies found that many of the pediculicides in the market are either not fully effective or are ineffective when they are used according to the instructions.[3][4][5][6]

    Pediculicides may rapidly lose their efficacy because of the development of resistance. Resistance of head lice to insecticides such as lindane, malathion, phenothrin and permethrin has been reported.[7][8][9]

    Ivermectin (which can be given orally) has been shown to reduce levels of louse infestation.[10][11][12] Ivermectin is not approved by the FDA for pediculosis, though it is approved for onchocerciasis and strongyloidiasis.[2][13]

    Natural products
    Natural products tested clinically and found to be safe and effective could be very important in the control of head lice, as the complexity of the active ingredients may prevent the rapid development of resistance. They are more acceptable to some parents who are concerned with the use of chemical pediculicides. Several plant products such as aniseed, coconut, neem and tea tree oils offer promise for new compounds to treat head lice infestation. However, the number of clinical studies is very limited, and most have methodological problems such as lack of a comparison group. Plain vaseline also works and is non-harmful, though messy: like all animals, lice need to breathe, and smothering hair with vaseline or other oily/fatty substances (like the aforementioned plant oils) for several hours will asphyxiate them. Removing the oily substance itself can be somewhat difficult; in such a case a highly-foaming soap will be needed. Vinegar is also effective and safe in the treatment of pediculosis. Hair is drenched in warm vinegar, and then a shower cap is put in order to suffocate adult lice and erode egg walls (rendering them unviable). The cap should be worn overnight or at least for six hours.

    Enzyme-based products
    Certain protease enzymes can have insecticidal effects. This process works through using naturally occurring enzymes similar to those within the insects themselves. These protease enzymes cause the insect to hatch and molt prematurely, destroying the creature’s exoskeleton. These enzymes are similar to those found in meat tenderizers and digestive aids. The benefits of this type of treatment is that the lice do not develop resistance and these products are less toxic.

    Silicone-based lotions

    Dimethicone is a silicone oil, which coats and smothers the lice causing their death either by suffocation or dehydration. Most dimethicone lotions do not kill nits because the nits have only one breathing orifice, the operculum, so the dimethicone has less access there.—-Accelerated Nano X-ray tomography of headlice treated with Silcap(4% dimethicone/96% mineral oil) ([3]). After 15 min the lice and nits are suffocated and dry out. Courtesy of Oystershell NV & University of Ghent—-Therefore most treatments should be repeated after 7–10 days to kill any lice that hatch from the eggs or to treat reinfection by family members or class mates .[15] Combination lotions and foams exist (Silcap,[16] manufactured by Oystershell NV) that have an immediate effect on nits (15 min, 96% mortality) by combining the rather viscous dimethicone with penetrating excipients that increase the delivery through the abdominal spiracles of adults and the operculum of the nits.[17] However, “Silcap is not yet available in the US. Import and distribution is still waiting for final FDA approval.”[18]

    Gasoline/kerosene (not recommended)

    The use of kerosene or gasoline for prevention or treatment of lice is extremely dangerous due to the inherent fire hazard.[19][20] Since 1989, there have been at least nine cases of children being severely burned during such attempts. These cases apparently occurred because, contrary to popular belief, it is the fumes of the gasoline, rather than the liquid itself, that are flammable. These fumes can ignite due to the presence of even a small spark or open flame – such as those caused by electrical appliances, cigarette lighters, or pilot lights in stoves and water heaters. The use of gasoline to treat lice also carries a high risk of dermatitis (i.e. irration of the scalp).[21]—-Before gasoline (Petrol) was used as fuel, it was sold in small bottles as a treatment against lice and their eggs. At that time, the word Petrol was a trade name.

     

    Alcohol——–Common rubbing alcohol, when applied to the head, has been known to kill both the adult lice and the eggs.[22][23] Alcohol can be used as a remedy for pediculosis either by using a fine comb and dipping it in alcohol before combing, which is simply a way to increase the effectiveness of combing by rising the chances of killing any lice that the comb misses, or by soaking the head in a large quantity of alcohol and leaving it for a while, either with or without some means to stop the alcohol from evaporating, such as a shower cap. Alcohol use, however, implies certain risks: the scalp can suffer irritations, for example, or it could get into the eyes and cause severe pain and discomfort.

    Research
    A number of promising compounds are currently in development for the treatment of head lice. Approval of any of these products may make it much easier to treat head lice in the future.

    · Summers Laboratories is developing a benzyl alcohol-based treatment that kills by asphyxiation (Summer’s Non-pesticide Lice Asphyxiator). This product is a water-soluble gel similar in consistency to a hair conditioner. It consists of a mixture of dermatological and cosmetic ingredients. The active ingredient is benzyl alcohol. The product was acquired by Sciele Pharma for distribution in the United States, Canada, and Mexico. The product was recently approved by the FDA and is being marketed under the brand name Ulesfia.

    · ParaPRO is developing a crème rinse containing a novel biologically derived pesticide, Spinosad.[24] The product, tentatively branded NatrOVA, is currently being tested in FDA approved clinical trials.

     

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    The Corporate Corruption of Organics—

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    Government take over of Children with Parental Consent

    Australian Government Moves To Quickly Pass Laws To Sterilize, Electroshock, And Restrain Children Without Parental Consent
    http://preventdisease.com/news/12/030512_Australian-Government-Moves-To-Quickly-Pass-Laws-To-Sterilize-Electroshock-And-Restrain-Children-Without-Parental-Consent.shtml

    Another draft mental health bill, this time in Australia is mirroring global efforts in what is now an international and deliberate surge by government officials to remove parental consent. If passed, the shocking new law will allow children who are considered sufficiently mature, to be subjected to horrifying procedures including sterilization and electroshock.

    An important message by the Director of Applied Scholastics in Western Australia based in Perth, Alison Tarrant was sent to the public on behalf of The Athena School. “Some very disturbing information has come across our path in relation to a Draft Mental Health Bill which concerns our precious children and our rights as parents,” said Tarrant in a statement in the February 29, 2012 letter.

    Tarrant initially thought the information lacked authenticity and was later astonished when she found out the document was legitimate. “When I read it I was quite shocked and thought someone was playing a joke on me but then I went onto the main website http://www.mentalhealth.wa.gov.au which is the Government Department of the Mental Health Commission and looked at the actual Draft Bill,” she added.

    PreventDisease.com recently reported that vaccinating without parental knowledge will soon become the norm across the world. There is now a confirmed global initiative to remove any consent parents have to safeguard their children’s health while simultaneously removing any chance of informed consent by those who are considered of “mature” age regardless of their status as a child or teenager. These proposed bills are poised to become law and their frequency is increasing, especially in the U.S, U.K, Canada, Australia.

    Some of the more disturbing clauses draft mental health bill include:

    CHILDREN OF ANY AGE TO CONSENT TO STERILISATION: If a psychiatrist decides that a child (under 18 years) has sufficient maturity, he or she will be able to consent to sterilisation. Parental consent will not be needed. Only after the sterilisation procedure has been performed does it have to be reported and then only to the Chief Psychiatrist. [Pages: 135 & 136 of the Draft Mental Health Bill 2011]
    12 YEAR OLDS WILL BE ABLE TO CONSENT TO PSYCHOSURGERY: Banned in N.S.W. and the N.T., psychosurgery irreversibly damages the brain by surgery, burning or inserting electrodes. This draft bill proposes to allow a 12 year old child, if considered to be sufficiently mature by a psychiatrist, to be able to consent to psychosurgery. Once the child has consented it goes before the Mental Health Tribunal (MHT) for approval. Parental consent is also not needed for the MHT to approve the psychosurgery. [Pages: 108, 109, 110, 197,198, 199, 213]
    12 YEAR OLDS WILL BE ABLE TO CONSENT TO ELECTROSHOCK (ECT): Electroshock is hundreds of volts of electricity to the head. Any child aged 12 and over, whom a child and adolescent psychiatrist decides is “mature” enough, will be able to consent to electroshock. Also, once consent is given, there is no requirement for parents or anyone, including the MHT, to approve the electroshock. Electroshock should be banned. Its use on the elderly, pregnant women and children is especially destructive. [Pages: 100, 101, 103, 104, 194, 105]
    RESTRAINT AND SECLUSION OF CHILDREN: Children can be restrained in a psychiatric institution, with the use of mechanical restraint (manacles, belts, straps etc.) and bodily force. Chemical restraint – the use of psychiatric drugs to subdue and control the person – is not covered in the draft bill, so there are no legal safeguards to prevent its application. Death can result from all forms of restraint. [Pages: 122, 121, 113, 246]
    INVOLUNTARY COMMITMENT OF CHILDREN: A psychiatrist can involuntarily detain any child for up to 14 days if “suspected” of mental illness. Parents will not be able to discharge their child during this period and take them home. The psychiatrist can then make a “continuation order” to continue the detainment for up to 3 months and thereafter for each subsequent 3 month period. During detainment, the child could be drugged, restrained, secluded, given electroshock if over 12 and could be put into a ward with adults. Parental consent is not required to continue the detainment or for any treatment, including the child being placed on a legal order to continue to receive drugs at home. The MHT hold hearings on the detainment of a child, but there is no guarantee the child will be able to go home. In 2010/11 there were 1,248 hearings for all ages and only 58 people had their status changed from involuntary to voluntary. [Pages: 21, 22, 35, 19, 107, 36, 53, 54, 183 -185, 190, 191, 213, 214,18, 46, 47, 48, 65, 66, 70, 73, 75-77]
    WHO WILL BE ABLE TO DETAIN A CHILD IS NOT FULLY KNOWN: An “authorised mental health practitioner” can also detain a child or adult in the draft bill. Exactly who an authorised mental health practitioner is, is not defined by the draft bill. The Chief Psychiatrist can literally give anyone or any profession the power to detain someone just because he considers they are qualified and by publishing the decision in the Gazette. This clause must be removed from the Draft Mental Health Bill 2011. Only a judge or magistrate should have the power to order someone be detained, and only with full legal representation for the person facing depravation of liberty [Pages: 246, 247, 21, 22]
    WHO IS RESPONSIBLE FOR THIS DRAFT BILL?: The Western Australia Mental Health Commission (MHC) were responsible for writing the Draft Mental Health Bill 2011, with Mental Health Commissioner and clinical psychologist, Mr Eddie Bartnik overseeing the process.

    Tarrant suggests everybody write a letter saying exactly what you think of this absurd legislation. Write expressing your objections to the Mental Health Commission and to your state legislator.

    Email: on contactus@mentalhealth.wa.gov.au or

    Mail: GPO Box X2299 Perth Business Centre, W.A. 6847Â Â

    Send a copy of your objections to the Mental Health Minister, Health Minister and your local Member of Parliament.

    Find their addresses at: http://www.parliament.wa.gov.au/parliament/memblist.nsf/WAllMembers

    Please don’t let your citizenship stop you from speaking out against these human rights violations. This destructive movement against humanity is global and it’s a pressing concern of grand proportions. If we don’t speak out now, the health and safety of future generations are in serious jeopardy.

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    Vaccinating Without Parental Knowledge Soon To Become The Norm Across The World
    http://preventdisease.com/news/11/092811_Vaccinating-Without-Parental-Knowledge-Soon-To-Become-The-Norm-Across-The-World.shtml

    Health officials in the U.S, U.K, Canada, Australia and around the world are officially crossing into dangerous territory with parents when it comes to vaccinations. Not only are public health entities habitually and deliberately failing to inform the public of their right to refuse vaccines in both school and work settings, but they are working towards mandatory vaccination protocols which will allow officials to conduct childhood vaccinations without any parental consent at all.

    It was just a little over one year ago when the pharmaceutical industry, the Department of Health and Human Services, and Centers for Disease Control allocated millions of dollars in funding to establish vaccine clinics in public schools, causing a huge uproar from concerned parents.

    The RAND Corporation, paid by Sanofi Pasteur, outlined how to turn schools into vaccine clinics, which critics claimed will inevitably poison children with multi-dose vaccines.

    These school based health centers (SBHCs) are located in school settings that claim to provide children and adolescents with comprehensive primary, acute, and preventive care for physical and mental health conditions. The following report Are We ‘Making the Grade’ With Our Children is a concise overview of school based vaccination centers and their objectives.

    SBHCs are becoming a matter of routine in other countries such as Australia, where the focus has been to implement the same HPV vaccination programs. Queensland Health has so far finalised arrangements with approximately almost 800 schools to offer the HPV vaccine to students.

    Naturopathic Doctor and vaccine researcher, Dave Mihalovic stated that public health agencies are pushing the centers in the guise of preventive medicine, when they will effectively promote the opposite. “The centers are providing an entry portal for pharmaceutical giants to access student health records and provide dangerous treatments such as untested drugs and vaccines without the full informed consent of parents.”

    Consent packets are sent home by the school, completed by a parent/guardian, and then returned to the school. Vaccines are provided during the school day by nursing staff. Parents are not required to be present.

    The consent forms are a one-time process, meaning parents will not have to submit consent more than once regardless how many vaccines their child receives. “This leaves the door open for the injection or administration of any drug treatment to the child which the school’s health staff deems appropriate, without any informed consent by the parents on the treatment’s effects, contraindications or consequences,” said Mihalovic.

    “It’s certainly an incredibly advantageous position for big pharma,” said Mihalovic. The decisions will ultimately be between parents and the respective policy makers of school system, however the responsibility to make the right decision will lie solely with the parents. “Any parent who would not sound the alarm at a policy that does not inform them of every single injection, drug or treatment to their child is simply not paying attention to the potential consequences,” concluded Mihalovic.

    Republican presidential candidate Rick Perry recently came under fire from the public and his opposition for an executive order mandating the HPV vaccine as a requirement for young girls without their informed consent or that of their parents.

    One of the most concerning issues relating to Perry’s executive order is that HPV has been repeatedly shown not to cause cervical cancer, and that it is the persistant infection, not the virus, that determines the risk. More than 90% of women initially infected with a particular strain of HPV will not show the same strain four menstrual cycles later making the vaccine useless. Another astonishing fact, as shown by a CDC study, is that HPV types 16 and 18, the two HPV vaccine-relevant strains, are NOT the prevalent types in American women. Three published papers on HPV prevalence in the U.S., indicated that types 62, 84 and 52 are the most prevalent. None of these are targeted in either approved HPV vaccine, and type 52 is an accepted high-risk “carcinogenic” strain of HPV.

    SANE Vax, Inc. recently informed the FDA that the Gardasil HPV vaccine currently on the market has been found to be contaminated with residual recombinant HPV DNA. This hitherto unknown contaminant may have provided a scientific basis for Gardasil-induced autoimmune-based inflammatory diseases in various tissues, including inflammation in the joints and central nervous system.

    SANE Vax contracted with an independent lab to test for contamination and found HPV recombinant DNA (rDNA) in 13 vaccine vials. The Gardasil vials with different lot numbers were from New Zealand, Australia, Spain, Poland, France and three states in the U.S. 100% of the samples tested positive for the presence of the genetically modified HPV DNA.

    The state of California recently passed bill AB499, permitting minors as young as 12 years old to be vaccinated with vaccines such as Gardasil without parental knowledge or parental consent. The worst part is that parents will still be legally and financially responsible for their child EVEN IF severe damage results from the SECRET vaccinations without parental consent.

    The overbearing reach of public health officials extends far beyond the United States. As vaccine examiner noted last year, a ‘demonstration project’ conducted by PATH International in cooperation with ICMR and the Indian state governments and funded by the Bill and Melinda Gates Foundation was called to an abrupt halt amidst allegations of unethical conduct.

    58 various health advocacy groups took it upon themselves to conduct an independent fact finding mission when reports of 4 unexplained deaths and 120 girls suffering from debilitating new illnesses after being vaccinated against the HPV virus.

    In Canada, health officials routinely ignore the fact that there are no laws that can force a person to be vaccinated against their will. Parents are often pressured to vaccinate their young infants with the threat that the child won’t be allowed in school — even though most provinces don’t have acts legislating compulsory vaccination.

    In the three provinces (Ontario, New Brunswick and Manitoba) that have legislation for school-entry vaccinations, parents are rarely told that exemptions for reasons of conscience and/or religion exist within these laws to allow their children to opt out of having any shots.

    Although there is no specific law in British Columbia that governs vaccination for school entry, the Infant’s Act gives health officials a veritable carte blanche to perform medical procedures on children without parental knowledge and consent. The Vaccine Risk Awareness Network (VRAN) has been contacted on several occasions by parents whose children were hauled in by school nurses and vaccinated against their will despite the child’s protest that they were not to get any vaccines.

    In Burnaby, BC, parents have been infuriated by the lack of parental consent obtained by health authorities. A Burnaby mom was one of those parents upset that her 13-year-old daughter was vaccinated for HPV without her parental consent. “She didn’t bring home any forms or anything,” said Rosemary Reid. “I had absolutely no idea.”

    The BC based Fraser Health Authority states they try to get parental consent, and if the girls don’t bring the forms back, it’s up to a public health nurse to decide if they are mature enough to give informed consent. “This informed consent thing, I don’t think I agree with it. I think it should still be up to the parents. You can take some kids into a room and brainwash them,” she said. “They’re only 13 and 14.” Fraser Health spokesperson Lisa Thibault said kids can overrule parental objection if they’re deemed mature enough by a public health nurse, and it’s the nurse’s responsibility to make that assessment.

    At issue, of course, is whether 12-, 13- or 14-year-olds are mature enough to fully analyze the benefits versus risks of vaccination (or any medical treatment for that matter), or recognize the alternatives.

    On a broader level, the vaccine situation involving nursing students, students in teachers’ college, dental tech students, health care workers and workers in nursing homes is fairly grim. These people are often threatened with expulsion and job loss if they refuse to submit to hepatitis B, tuberculosis tests or flu shots.

    Health workers who refused the flu shots have been laid-off their nursing home jobs without pay when cases of flu have broken out. Those who do agree to get the flu shot are required to sign a waiver that absolves the institution, the union and the pharmaceutical company from any liability for damages should health injury or disabilities occur from vaccine reactions.

    In the U.K, nurses regularly disregard the wishes of parents relating to the health and welfare of their children. U.K department of health does not deny that parental consent is desirable but not essential. Family rights campaigners called for a change in the law one year ago after it was revealed that girls as young as 12 can be given the cervical cancer vaccine without their parents’ consent. Doctors and nurses have been told they are under no legal obligation to seek the permission of the parent or guardian.

    Norman Wells, director of Family and Youth Concern, said: ‘Giving the vaccination to girls without the consent of their parents is unethical and a recipe for disaster. “It is sending out the message that girls under 16 have a right to a private sex life and is treating parents with contempt.”
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    U.K Doctors have reported that girls aged just 12 and 13 have suffered paralysis, convulsions and sight problems after being given the HPV vaccine.

    Family doctors in the U.K have even been accused of administering the MMR jab by stealth to children coming into their surgeries to receive other vaccinations. At least 50 horrified parents have complained that their GPs have ‘mistakenly’ given their children the combined measles, mumps and rubella vaccine, it has emerged.

    Studies sponsored by pharmaceutical giants continue to embark on several qualitative and quantitative research projects to show biased results on how to assess the competency of consent from children for vaccinations. BMC Public Health published a study in 2009 which claimed to demonstrate that health providers have a duty of care to girls for whom no parental consent for HPV vaccination has been given, and in the UK, this includes conducting, and acting upon, an assessment of the maturity and competence of an adolescent minor.

    The British Journal of Cancer published a clinical study on HPV vaccination among ethnic minorities in the UK: knowledge, acceptability and attitudes, to assess what they refer to as unique opportunities for the “primary prevention” of cervical cancer. The background statement alone was erroneous and false before the study was even initiated. Vaccination has never been proven on any scientific grounds to be a primary prevention tool for cervical cancer.

    Regardless, the quantitative study assessed ethnic differences in knowledge and acceptability of HPV vaccination in the UK to attempt to validate informed consent and refusal of HPV vaccination in ethnic communities.

    The study further demonstrates how desperate vaccine manufacturers have become to obtain public acceptance for bypassing informed consent. The need to initiate a study to derive data on the differentiation between ethnicity, religion and other factors to define acceptability of informed consent is not only immoral, but also shows a complete disregard for what consent represents as a human right.

    The right to “informed consent” when considering any medical procedure or drug, is a fundamental human right and a key medical ethic that governs medical law in almost every country in the world. This ethic has grown from the Nuremberg trials after World War II. It forbids human experimentation and the use of force or intimidation in medical procedures.

    The institutions that are using these strong-arm tactics are in violation of fundamental medical ethics and must be challenged forcefully if we are to preserve what remains of health freedom for humanity. The unions who have conspired with the various institutions to enforce vaccination must also be called to task for failing to protect children and workers’ rights from medical coercion and battery.

    At the pinnacle of defending our health freedoms, we need to muster strength in numbers as the majority to secure amendments that will guarantee freedom of choice in health, and protection from enforced medication at all costs.

    Sources:
    ncbi.nlm.nih.gov– canada.com–dailymail.co.uk –sanevax.org–alive.com
    nature.com–huffingtonpost.com

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    Show of the Week April 13-2012

    Food Ingredients Most Prone to Fraudulent Economically Motivated Adulteration
    Bitter melon extract impairs prostate cancer cell-cycle progression and delays prostatic intraepithelial neoplasia in TRAMP model

    Link Between Estrogen and Tobacco Smoke: Estrogen May Help Promote Lung Cancer

    The Power of Turpentine( Terebinth )

    Some of the listings for Terebinth ( Turpentine )

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    Food Ingredients Most Prone to Fraudulent Economically Motivated Adulteration
    A variety of foods. Researchers found that the top seven adulterated ingredients were olive oil, milk, honey, saffron, orange juice, coffee, and apple juice.

    ScienceDaily (Apr. 5, 2012) — In new research published in the April Journal of Food Science, analyses of the first known public database compiling reports on food fraud and economically motivated adulteration in food highlight the most fraud-prone ingredients in the food supply; analytical detection methods; and the type of fraud reported. Based on a review of records from scholarly journals, the top seven adulterated ingredients in the database are olive oil, milk, honey, saffron, orange juice, coffee, and apple juice.—The database was created by the U.S. Pharmacopeial Convention (USP), a nonprofit scientific organization that develops standards to help ensure the identity, quality and purity of food ingredients, dietary supplements and pharmaceuticals. USP’s food ingredient standards are published in the Food Chemicals Codex (FCC) compendium. The new database provides baseline information to assist interested parties in assessing the risks of specific products. It includes a total of 1,305 records for food fraud based on a total of 660 scholarly, media and other publicly available reports. Records are divided by scholarly research (1,054 records) and media reports (251 records). Researchers are Drs. Jeffrey C. Moore (lead author) and Markus Lipp of USP, and Dr. John Spink of Michigan State University.

    Food fraud was recently defined in a report commissioned by the Department of Homeland Security and funded by the National Center for Food Protection and Defense (University of Minnesota) as a collective term that encompasses the deliberate substitution, addition, tampering or misrepresentation of food, food ingredients or food packaging, or false or misleading statements made about a product for economic gain. A more specific type of fraud, intentional or economically motivated adulteration of food ingredients has been defined by USP’s Expert Panel on Food Ingredient Intentional Adulterants as the fraudulent addition of nonauthentic substances or removal or replacement of authentic substances without the purchaser’s knowledge for economic gain of the seller.”This database is a critical step in protecting consumers,” said Dr. Spink. “Food fraud and economically motivated adulteration have not received the warranted attention given the potential danger they present. We recently defined these terms [see the Journal of Food Science, November 2011] and now we are defining the scope and scale. As many do not believe a concept or risk exists if it does not appear in a scholarly journal, we believe that publication of this paper in the Journal of Food Science will allow us to advance the science of food fraud prevention.”

    While traditionally considered primarily an economic issue and less a consumer safety threat, authors of the paper, Development and Application of a Database of Food Ingredient Fraud and Economically Motivated Adulteration from 1980 to 2010, defined empirically that in some ways food fraud may be more risky than traditional threats to the food supply. The adulterants used in these activities often are unconventional and designed to avoid detection through routine analyses. Melamine, for example, was considered neither a potential contaminant nor an adulterant in the food supply before the episodes of adulteration of pet food in 2007 and infant formula and other milk products in 2008 (with tainted products still appearing sporadically today, principally in China). Although, as records from this database indicate, melamine was used as an adulterant to mimic protein as early as 1979; however, this remained virtually unknown until 2007. Hence, testing for melamine was not included in routine quality assurance or quality control analyses.

    Additionally, current food protection systems are not designed to look for the nearly infinite number of potential adulterants that may show up in the food supply.

    “Food ingredients and additives present a unique risk because they are used in so many food products and often do not have visual or functional properties that enable easy discrimination from other similar ingredients or adulterants throughout the supply chain,” the paper states. Glycerin, for example, is a sweet, clear, colorless liquid that is difficult to differentiate by sight or smell from other sweet, clear, colorless liquid syrups — including toxic diethylene glycol, which in the past has been substituted for glycerin with deadly consequences. Diethylene glycol has been fraudulently added to wines, and also used as an adulterant of glycerin used in pharmaceuticals.

    In addition to identifying specific food ingredients and food categories vulnerable to adulteration, the researchers also analyzed the types of analytical detection methods used to discover the fraud, as well as the type of fraud using three categories: replacement, addition or removal. The authors found 95 percent of records involved replacement — an authentic material replaced partially or completely by another, less expensive substitute. An example is the partial substitution of olive oil with hazelnut oil. Other examples include potentially harmful substitution of toxic Japanese star anise for Chinese star anise (a common spice used in foods), and the partial replacement of low-quality spices with lead tetraoxide or lead chromate to imitate the color of higher-quality spices.

    Utility of Database

    The database provides information that can be useful in evaluating current and emerging risks for food fraud. In addition to providing a baseline understanding of the vulnerability of individual ingredients, the database offers information about potential adulterants that could reappear in the supply chain for particular ingredients. For example, records in the database regarding melamine as an adulterant for high-protein-content ingredients date back to 1979. Speaking to that example, the paper notes, “Perhaps if this information had been readily available to risk assessors before the 2007 and 2008 incidents of melamine adulteration and wheat gluten and milk powders, it could have helped risk assessors anticipate these adulteration possibilities.” This information also could have stimulated research aimed at developing new methods to measure protein content, which could signal adulteration with melamine and other unexpected constituents — an effort that has only recently gained substantial interest.

    Another practical application of the database involves analytical testing strategies to detect food fraud. A commonly used strategy at present is testing for the absence of specific adulterants — an approach that excels at detecting known adulterants at very low levels but has the critical limitation of not necessarily being able to detect unknown adulterants. An alternative strategy is compendial testing (via FCC and other sources) for the identity, authenticity and purity of a food ingredient (i.e., what should be present and in what quantity instead of what should not be present). While this testing may not always be capable of detecting adulterants at trace levels, it is capable of detecting both known and unknown adulterants. “Well-designed compendial testing approaches can be very powerful tool for guarding against food fraud,” said Dr. Moore. “Their potential to detect both unknown and known adulterants is a significant benefit in an environment where no one knows and is worried about what harmful adulterant criminals will use to create the next generation of fake food ingredients.” The USP Food Fraud Database is publicly accessible at http://www.foodfraud.org.

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    Bitter melon extract impairs prostate cancer cell-cycle progression and delays prostatic intraepithelial neoplasia in TRAMP model.

    Cancer Prev Res (Phila). 2011 Dec;4(12):2122-30—Authors: Ru P, Steele R, Nerurkar PV, Phillips N, Ray RB

    Abstract
    Prostate cancer remains the second leading cause of cancer deaths among American men. Earlier diagnosis increases survival rate in patients. However, treatments for advanced disease are limited to hormone ablation techniques and palliative care. Thus, new methods of treatment and prevention are necessary for inhibiting disease progression to a hormone refractory state. One of the approaches to control prostate cancer is prevention through diet, which inhibits one or more neoplastic events and reduces the cancer risk. For centuries, Ayurveda has recommended the use of bitter melon (Momordica charantia) as a functional food to prevent and treat human health related issues. In this study, we have initially used human prostate cancer cells, PC3 and LNCaP, as an in vitro model to assess the efficacy of bitter melon extract (BME) as an anticancer agent. We observed that prostate cancer cells treated with BME accumulate during the S phase of the cell cycle and modulate cyclin D1, cyclin E, and p21 expression. Treatment of prostate cancer cells with BME enhanced Bax expression and induced PARP cleavage. Oral gavage ( feeding this through a tube into the stomach direct ) of BME, as a dietary compound, delayed the progression to high-grade prostatic intraepithelial neoplasia in TRAMP (transgenic adenocarcinoma of mouse prostate) mice (31%). Prostate tissue from BME-fed mice displayed approximately 51% reduction of proliferating cell nuclear antigen expression. Together, our results suggest for the first time that oral administration of BME inhibits prostate cancer progression in TRAMP mice b

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    Link Between Estrogen and Tobacco Smoke: Estrogen May Help Promote Lung Cancer

    ScienceDaily (Apr. 3, 2012) — The hormone estrogen may help promote lung cancer — including compounding the effects of tobacco smoke on the disease — pointing towards potential new therapies that target the hormone metabolism, according to new research presented at the AACR Annual Meeting 2012 on April 3 by scientists at Fox Chase Cancer Center in Philadelphia.—“This research provides the link between estrogen and tobacco smoke,” says study author Jing Peng, PhD, postdoctoral associate in the lab of Margie L. Clapper, PhD, also a co-author on the paper.—The researchers found that estrogen is metabolized into toxic derivatives in the mouse lung. The level of these toxic metabolites increased when mice were exposed to tobacco smoke. The results suggest that new therapies which prevent estrogen from being converted into toxins could one day help treat — or even prevent — lung cancer, says Peng. “In the future, we would like to target estrogen-metabolizing pathways as a form of treatment or prevention of lung cancer.”—Researchers have long known that tobacco smoke is the number one cause of lung cancer. But recent findings suggest that estrogen may also play a role in the disease. If so, it wouldn’t be the first form of cancer linked to estrogen — this hormone is known to promote breast cancer as well as other gynecologic cancers.—To investigate, Peng, Clapper and their colleagues examined the lungs of healthy mice and found that they contained high levels of estrogen metabolites, known as 4‑hydroxy- estrogens (4-OHEs), which are carcinogenic. Specifically, these 4-OHEs help activate processes that promote cell growth, and generate free radicals that damage cells.—When the researchers exposed the mice to tobacco smoke for 8 weeks, they found that the levels of 4-OHEs increased. “We believe that these metabolites of estrogen can damage cells and contribute to lung cancer,” says Clapper.—Female mice had twice as much 4-OHE in their lungs compared to male mice after controlling for the level of total estrogen present. Whether this is the same in humans remains to be determined. “While lung cancer is not more common in women, the number of nonsmokers who develop lung cancer is greater for men than for women,” explains Clapper.—In the future, Peng and Clapper hope these results will help researchers develop new therapies that target estrogen metabolism as a way to treat or prevent lung cancer. Already, patients are enrolling in clinical trials that are using anti-estrogen drugs to treat lung cancer.—“We believe that levels of these toxic estrogen metabolites may one day be useful in predicting a person’s lung cancer risk or prognosis,” adds Peng. “If levels are particularly high, for instance, that may suggest the person is more prone to developing the disease, or has a worse prognosis. We’d definitely like to be able to use this information to develop a more personalized treatment approach,” she says.

    Other co-authors include Lisa Vanderveer, from Fox Chase, as well as researchers from SAIC-Frederick, Inc. and Duke University. The work was supported by funds from the Estate of Jane Villon and the Kitty Jackson Fund.—Story Source-The above story is reprinted from materials provided by Fox Chase Cancer Center.

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    The Power Of Turpentine-Terebinth

    Terebinth has been used in the past for a host of healings —from arthritic to respiratory –kidney and organ restoration—it has a enema effect from removing narcotic poisoning by applying 2”1 ratio of olive oil ( any carrier that is thick) to 1 part turpentine to be taken internally—it has stimulating Qualities to the arterial and nervous system ( it would open any obstruction in the veins) Terebinth can cause an increase secretion of urine and relieve the back pains as a result of back up from the kidneys and reduce blood in the urine –has been used to remove the symptoms and causes of pleurisy—by applying it on the area—the old term was called a blister—this was when you heated the element( terebinth) and then took a cloth soaked it and wrung out and then pressed and applied this to the area—in this case either the back or the chest since this would cover a large area of the body-and allowed to be there between 15 minutes to 30 minutes depending on the sensitivity of the skin—

    A enemata ( a means to void out waste material from the colon) was used to remove narcotics or other toxins from the colon –the method was taking 1 tablespoon to 1 oz and doubling the oil ( a preferred heavier oil like olive or ghee-or coconut etc ) mixing them together and consuming them—this was also used to clear up a ulcer in the stomach ( good chance it would probably knock out Gerd or Hy Pylori ) the method was to take equal parts of terebinth and castor oil and consume them—it was used as well as a vermifuge ( removing worms form the body )—For Typhoid or Enteric Fever ( this is a fever brought on by drinking water that has fecal matter exposed to it ) the remedy was to take 10 drops every 2 hours during the day and every 3 hours at night ( usually applied to a sugar cube to be taken orally that way—must have a carrier )-it removed all the negative symptoms—For Typhoid Bronchitis or Pneumonia an exterior application and an interior one was the method of use to correct the body—for Purpura hemorrhage ( purple bleeding ) a skin condition where there is internal bleeding under the skin giving it a purple appearance —terebeinth clears it up as well

    Some of the listings for Terebinth ( Turpentine )

    Internal Uses for Terebinth –Turpenine

     

    Modifies tracheo-bronchial secretions

    Haemostatic ( slows down or stops bleeding )

    Diuretic

    Antitheumatic

    Antidote to Phosphorus Poisoning

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    Indications

    Chronic and Fetid Bronchitis Pulmonary TB ( lung TB)

     

    Leucorrhia ( vaginal discharge)

    Haemorrhage ( intestinal-pulmonary-uterine-haempohilia-nose bleeds )

    Oliguria ( diuretic like effect)

    Rheumatism ( painful body )

    Flatulence

    Intestinal Parasites ( especially worms )

    Epilepsy

    Phosporus Antidote
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    External Uses For Terebinth-Turpentine-

     

    Parasiticide

    Revulsive ( counter irritant or antidotal)

    ~~~~~~~~~~~~~~~~~~~~~~~~~~~

    USES

    Rheumatism-Gout-Neuralgia-Sciatica

    Scabies or Lice

    Puerporal Infections ( bleeding under the skin –purple spots )

     

     

    Internal Uses for Terebinth –Turpenine

     

    Genitor-Urinary Antiseptic ( used as a douche as well injectable

    Dissolves Gallstones

    Antispasmodic

    Vermifuge ( removes worms and parasites

    ~~~~~~~~~~~~~~~~~~~~~~~~~~~

    Indications

    Urinary and Renal Infections-cystitis urethritis ( inflammation of the urethra )

    Puerperal Fever-( infection of the uterus after birth )

    Gallstones

    Dropsy (excess water retention of organs or tissue )

    Spasms ( Colitis-whopping Cough )

    Migraine

    Chronic Constipation

     

    ~~~~~~~~~~~~~~~~~~~~~~~~~~~

    External Uses For Terebinth-Turpentine-

     

    Analgesic

    Antiseptic

     

    ~~~~~~~~~~~~~~~~~~~~~~~~~~~

    USES

    Atonic wounds( a slow healing wound or a damaged or weakened muscle-Sores and Gangrenous wounds

    Leucorrhea

     

     

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    TOP D

    HOME

    Show of the Week April 16-2012

     

    Food Ingredients Most Prone to Fraudulent Economically Motivated Adulteration
    Kill the Natural Health Products Bill, kill the Food Bill

    Coffee Power in the old Days

    Banned Antibiotics Found in Poultry Products

    Supplementation with Pycnogenol® improves signs and symptoms of menopausal transition

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    Food Ingredients Most Prone to Fraudulent Economically Motivated Adulteration
    A variety of foods. Researchers found that the top seven adulterated ingredients were olive oil, milk, honey, saffron, orange juice, coffee, and apple juice.

    ScienceDaily (Apr. 5, 2012) — In new research published in the April Journal of Food Science, analyses of the first known public database compiling reports on food fraud and economically motivated adulteration in food highlight the most fraud-prone ingredients in the food supply; analytical detection methods; and the type of fraud reported. Based on a review of records from scholarly journals, the top seven adulterated ingredients in the database are olive oil, milk, honey, saffron, orange juice, coffee, and apple juice.—The database was created by the U.S. Pharmacopeial Convention (USP), a nonprofit scientific organization that develops standards to help ensure the identity, quality and purity of food ingredients, dietary supplements and pharmaceuticals. USP’s food ingredient standards are published in the Food Chemicals Codex (FCC) compendium. The new database provides baseline information to assist interested parties in assessing the risks of specific products. It includes a total of 1,305 records for food fraud based on a total of 660 scholarly, media and other publicly available reports. Records are divided by scholarly research (1,054 records) and media reports (251 records). Researchers are Drs. Jeffrey C. Moore (lead author) and Markus Lipp of USP, and Dr. John Spink of Michigan State University.

    Food fraud was recently defined in a report commissioned by the Department of Homeland Security and funded by the National Center for Food Protection and Defense (University of Minnesota) as a collective term that encompasses the deliberate substitution, addition, tampering or misrepresentation of food, food ingredients or food packaging, or false or misleading statements made about a product for economic gain. A more specific type of fraud, intentional or economically motivated adulteration of food ingredients has been defined by USP’s Expert Panel on Food Ingredient Intentional Adulterants as the fraudulent addition of nonauthentic substances or removal or replacement of authentic substances without the purchaser’s knowledge for economic gain of the seller.”This database is a critical step in protecting consumers,” said Dr. Spink. “Food fraud and economically motivated adulteration have not received the warranted attention given the potential danger they present. We recently defined these terms [see the Journal of Food Science, November 2011] and now we are defining the scope and scale. As many do not believe a concept or risk exists if it does not appear in a scholarly journal, we believe that publication of this paper in the Journal of Food Science will allow us to advance the science of food fraud prevention.”

    While traditionally considered primarily an economic issue and less a consumer safety threat, authors of the paper, Development and Application of a Database of Food Ingredient Fraud and Economically Motivated Adulteration from 1980 to 2010, defined empirically that in some ways food fraud may be more risky than traditional threats to the food supply. The adulterants used in these activities often are unconventional and designed to avoid detection through routine analyses. Melamine, for example, was considered neither a potential contaminant nor an adulterant in the food supply before the episodes of adulteration of pet food in 2007 and infant formula and other milk products in 2008 (with tainted products still appearing sporadically today, principally in China). Although, as records from this database indicate, melamine was used as an adulterant to mimic protein as early as 1979; however, this remained virtually unknown until 2007. Hence, testing for melamine was not included in routine quality assurance or quality control analyses.

    Additionally, current food protection systems are not designed to look for the nearly infinite number of potential adulterants that may show up in the food supply.

    “Food ingredients and additives present a unique risk because they are used in so many food products and often do not have visual or functional properties that enable easy discrimination from other similar ingredients or adulterants throughout the supply chain,” the paper states. Glycerin, for example, is a sweet, clear, colorless liquid that is difficult to differentiate by sight or smell from other sweet, clear, colorless liquid syrups — including toxic diethylene glycol, which in the past has been substituted for glycerin with deadly consequences. Diethylene glycol has been fraudulently added to wines, and also used as an adulterant of glycerin used in pharmaceuticals.

    In addition to identifying specific food ingredients and food categories vulnerable to adulteration, the researchers also analyzed the types of analytical detection methods used to discover the fraud, as well as the type of fraud using three categories: replacement, addition or removal. The authors found 95 percent of records involved replacement — an authentic material replaced partially or completely by another, less expensive substitute. An example is the partial substitution of olive oil with hazelnut oil. Other examples include potentially harmful substitution of toxic Japanese star anise for Chinese star anise (a common spice used in foods), and the partial replacement of low-quality spices with lead tetraoxide or lead chromate to imitate the color of higher-quality spices.

    Utility of Database

    The database provides information that can be useful in evaluating current and emerging risks for food fraud. In addition to providing a baseline understanding of the vulnerability of individual ingredients, the database offers information about potential adulterants that could reappear in the supply chain for particular ingredients. For example, records in the database regarding melamine as an adulterant for high-protein-content ingredients date back to 1979. Speaking to that example, the paper notes, “Perhaps if this information had been readily available to risk assessors before the 2007 and 2008 incidents of melamine adulteration and wheat gluten and milk powders, it could have helped risk assessors anticipate these adulteration possibilities.” This information also could have stimulated research aimed at developing new methods to measure protein content, which could signal adulteration with melamine and other unexpected constituents — an effort that has only recently gained substantial interest.

    Another practical application of the database involves analytical testing strategies to detect food fraud. A commonly used strategy at present is testing for the absence of specific adulterants — an approach that excels at detecting known adulterants at very low levels but has the critical limitation of not necessarily being able to detect unknown adulterants. An alternative strategy is compendial testing (via FCC and other sources) for the identity, authenticity and purity of a food ingredient (i.e., what should be present and in what quantity instead of what should not be present). While this testing may not always be capable of detecting adulterants at trace levels, it is capable of detecting both known and unknown adulterants. “Well-designed compendial testing approaches can be very powerful tool for guarding against food fraud,” said Dr. Moore. “Their potential to detect both unknown and known adulterants is a significant benefit in an environment where no one knows and is worried about what harmful adulterant criminals will use to create the next generation of fake food ingredients.” The USP Food Fraud Database is publicly accessible at http://www.foodfraud.org.

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    Kill the Natural Health Products Bill, kill the Food Bill.

    The Food Bill is one leg of New Zealand’s compliance with Codex Alimentarius, the “Food Book” set of international food regulations being forced upon all World Trade Organisation states. The Natural Health Products Bill is the other leg.—Both legs will kick New Zealanders in the guts by benefiting international trade and multinational agribusiness / pharmaceutical corporations at the expense of our own food and health rights. That is what Codex Alimentarius is all about.–However, if the Natural Health Products Bill can be killed using the Select Committee process, combined with public outrage, then the Food Bill could be repealed without loss to the country in trade terms.—This is because killing the NHP Bill would void New Zealand’s Codex Alimentarius compliance. Codex compliance is NOT in your interests, be sure of that. And with NZ’s Codex compliance voided, there is no reason for the Food Bill to exist at all. The idea is to cut off one leg and the body will fall over, taking the other leg with it. Will it work? There is only one way to find out.–You’ll want to oppose the Natural Health Products Bill in any case. It is outrageous – and, luckily, very easy to read. Let’s try to bring it down.—-What’s wrong with the NHP Bill itself?—It makes it illegal without a licence to prepare, share or administer anything (that isn’t presented as “food”) that’s made from plants, vitamins, minerals or anything else natural and may have any of the following material health benefits:–The maintenance or promotion of health or wellness; nutritional support; vitamin or mineral supplementation; affecting or maintaining the structure or function of the body; effective treatment of any self-diagnosed or self-managed condition. Now, go back and read that again!—-You’ll be liable for a $50,000 fine for doing any of the above, even for yourself. No more home-grown camomile tea to make you sleep better. No more practising of traditional Maori medicine without a government ticket, which can be denied or revoked. No more home-made manuka oil to put on your cuts. No more using your granny’s remedies from the herb garden. None of this without permission, fees and rules, or you face massive fines and possibly jail. Sound familiar?–Now, you may not actually do these things. But you may wish to retain the right to do so. You may also wish to use any of these products or services in future. But under the NHP Bill they will be more expensive and much harder to find, because most practitioners / producers will be regulated and compliance-costed out of existence.—Don’t take our word for all this. Read the bill. It’s very easy to read, unlike the Food Bill, and easy to see the intent. It is the same intent as the Food Bill. The government wishes to own what goes into you (and thus own you). They say it is all for your safety, of course. Do you still believe that?–Take note: The Natural Health Products Bill was, like the Food Bill, passed at a first reading UNAMINOUSLY. EVERY MP voted for it. And the bill itself was a proud product of cooperation between the Green Party and National.—Are you getting wise to the Green Party yet? And are you getting wise to Parliament itself?

    The NHP bill is here: http://www.legislation.govt.nz/bill/government/2011/0324/latest/whole.html.

    In reading the NHP Bill, pay close attention to sections 5 (definitions), 6 (what is a natural health product), 20 and 21 (powers of the new health police) 28, 29 and 30 (requirements for licensing) 37 and 38 (penalties), 45 (delegation of powers to corporations), 47 (regulations applying to licensed practitioners – these will be CODEX regulations) and LAST BUT VERY IMPORTANT the Schedule of “Suitable classes of substances”… this is basically everything you ingest that is not food (which is already covered by the Food Bill) – so plants, extracts thereof, minerals, vitamins, amino acids etc that are taken to promote wellbeing. The stuff that, along with food itself, is essential for your life.

    Making a “submission” on the Natural Health Products Bill.

    We don’t recommend that you “submit” your say, in a sense of law, on this Bill. “Submitting” means “bowing down” and giving up all the rights you presumably wish to retain. You need to reserve all your rights. This can all be made clear in the “submission” process.—Numbers are important here. We need to flood the Select Committee with responses voicing disapproval of the Natural Health Products Bill and Codex Alimentarius, and by extension the Food Bill. This might just kill the Food Bill by proxy, by killing its Codex counterpart and stopping Codex from being implemented.—So please SHARE this info widely, and fast. The deadline is Friday, 24 February 2012. Please especially get this into health food groups etc on Facebook and beyond.

    What to write

    If you’re outraged, express it. At the bottom of what you write, write All Rights Reserved.–We’d suggest that the main thing to get across is opposition to Codex Alimentarius being imposed upon New Zealanders through the Natural Health Products Bill and the Food Bill. Codex does not serve people, it serves corporations.—Keep a copy of what you write. But please do write something. This needs many people to make it work. New Zealand is sleepwalking towards a corporate police state.–If you wish, you can also choose to talk / shout about your concerns at an actual Select Committee hearing. We think this would be a very good idea.—Finally if you really want to make the Select Committee sit up, send the suggested text below or some variation thereof and put its members on their Oaths of Office. If they screw up, they are out of Office, or worse.

    Make your “submission” on the Natural Health Products Bill here, by scrolling to the bottom of the page: http://www.parliament.nz/en-NZ/PB/SC/MakeSub/a/1/4/50SCHE_SCF_00DBHOH_BILL11034_1-Natural-Health-Products-Bill.htm

    [Note: If the link is changed (not unlikely) then you should still be able to navigate to the NHP Bill submissions page by following this path: Home (http://www.parliament.nz) > Parliamentary business > Select committees > Make a submission. The “Make a submission” page is currently at http://www.parliament.nz/en-NZ/PB/SC/MakeSub/. Get to the NHP Bill submission page itself by choosing Health Committee from the drop-down list of Select Committees, then hit go. Scroll to the bottom of the page that comes up to enter the captcha code and make the “submission”.]

    Suggested text:

    TAKE NOTICE

    To the Select Committee for the Natural Health Products Bill

    1 TAKE NOTICE that those Members of Parliament on the Select Committee have sworn to serve the Queen according to Law, and the Natural Health Products Bill appears to be unlawful serving as it does foreign interests and not the interests of the country of New Zealand, this because it has been introduced into New Zealand together with the Food Bill as part of this country’s compliance with CODEX ALIMENTARIUS, a World Trade Organisation directive that supports international trade agreements at the expense of the natural God-given rights of the people of this land to feed themselves and treat their own ailments themselves in any way they best see fit.

    2 TAKE NOTICE that I have not seen any evidence that CODEX ALIMENTARIUS serves the people of this land and I believe that no such evidence exists.

    3 TAKE NOTICE that I have not seen any evidence that the Natural Health Products Bill serves the people of this land and I believe that no such evidence exists.

    4 TAKE NOTICE that I have not seen any evidence that the Natural Health Products Bill together with the Food Bill representing as they do this country’s efforts to meet the World Trade Organisation’s CODEX ALIMENTARIUS guidelines serves the people of this land and I believe that no such evidence exists.

    5 TAKE NOTICE that I have not seen any evidence that the Natural Health Products Bill together with the Food Bill and New Zealand’s efforts to implement the CODEX ALIMENTARIUS guidelines is not in essence treasonous and a breach of te Tiriti o Waitangi on the issue of taonga or treasures at the very least and I believe that no such evidence exists.

    5 TAKE NOTICE that it is my belief that the Select Committee members should provide evidence in their findings and recommendations to Parliament that my concerns at paragraphs 2, 3, 4 and 5 above are completely unfounded, with the same to be provided upon their respective Oaths of Office, before they individually or collectively make any implicit or explicit recommendation by act or omission that the Natural Health Products Bill should in any way whatsoever be moved to a second reading in Parliament.

    [6, 7 etc… My other concerns about the Natural Health Products Bill are… delete this or add in as appropriate, removing the square brackets and writing to a MAXIMUM TOTAL OF 4000 CHARACTERS. You have about 1500 characters left.]

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    Coffee Power in the old Days—Back in the 18 century caffeine ( coffee ) was used as a stomachic aid-( which today we can verify as a pancreatic support)—it was given for chronic Catarrh of the stomach (Catarrh is a disorder of inflammation of the mucous membranes in one of the airways or cavities of the body )-it would appear to be overload in the digestive system of mucous- and migraine —caffeine has been used to alleviate or cure the condition-Diarrhea of phlithis ( A disease characterized by the wasting away or atrophy of the body or a part of the body.- Tuberculosis of the lungs.) Atonic Diarrhea (Looseness of the bowels ) caffeine assisted in regulating waste –black coffee raises the arterial tension-so it improves circulation and can be use when there is a low circulatory activity—it was used for headache treatment- especially for migraine—it was utilized as 1 grain (64.79891 milligrams { 65 mgs} )of coffee every half hour- or until there is relief—Caffeine has been useful for renal and cardiac Dropsy ( a condition where the organs droop or are loaded with fluids—today we call it edema ) used for edema of the stomach as well-It was used regularly by French physicians of the day for heart failure instead of digitalis-based on the study it slows the pulse and raises arterial tension-this would better distrubute blood flow- and was better at diuresis (increased excretion of urine ) the used to by the third day inject a gram-it was safer then digiatalis without the accumulation of the drug in the heart and better for balancing the heart and removing excess fluid
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    Banned Antibiotics Found in Poultry Products

    ScienceDaily (Apr. 5, 2012) — In a joint study, researchers at the Johns Hopkins Bloomberg School of Public Health and Arizona State University found evidence suggesting that a class of antibiotics previously banned by the U.S. government for poultry production is still in use. Results of the study were published March 21 in Environmental Science & Technology.—The study, conducted by the Bloomberg School’s Center for a Livable Future and Arizona State’s Biodesign Institute, looked for drugs and other residues in feather meal, a common additive to chicken, swine, cattle and fish feed. The most important drugs found in the study were fluoroquinolones — broad spectrum antibiotics used to treat serious bacterial infections in people, particularly those infections that have become resistant to old-er antibiotic classes. The banned drugs were found in 8 of 12 samples of feather meal in a multi-state study. The findings were a surprise to scientists because fluoroquinolone use in U.S. poultry production was banned by the U.S. Food and Drug Administration in 2005.—-This is the first time investigators have examined feather meal, a byproduct of poultry production made from poultry feathers, to determine what drugs poultry may have received prior to their slaughter and sale.-The annual per capita human consumption of poultry products is approximately 100 lbs, greater than that of any other animal- or vegetable-derived protein source in the U.S. To satisfy this demand, each year, the U.S. poultry industry raises nearly 9 billion broiler chickens and 80 million turkeys, according to the U.S. Department of Agriculture. A large percentage of the fresh weight of these animals is inedible — an estimated 33 percent for chickens, for example — and is recycled for other uses, including feather meal.—The rendering industry, which converts animal byproducts into a wide range of materials, processes poultry feathers into feather meal, which is often added as a supplement to poultry, pig, ruminant, and fish feeds or sold as an “organic” fertilizer. In a companion study, researchers found inorganic arsenic in feather meal used in retail fertilizers.—“The discovery of certain antibiotics in feather meal strongly suggests the continued use of these drugs, despite the ban put in place in 2005 by the FDA,” said David Love, PhD, lead author of the report. “The public health community has long been frustrated with the unwillingness of FDA to effectively address what antibiotics are fed to food animals.”—A primary reason for the 2005 FDA ban on the use of fluoroquinolones in poultry production was an alarming increase in the rate of the fluoroquinolone resistance among Campylobacter bacteria. “In recent years, we’ve seen the rate of fluoroquinolone resistance slow, but not drop,” noted study co-author Keeve Nachman, PhD, Farming for the Future Program Director at the Johns Hopkins Center for a Livable Future. “With such a ban, you would expect a decline in resistance to these drugs. The continued use of fluoroquinolones and unintended antibiotic contamination of poultry feed may help ex-plain why high rates of fluoroquinolone-resistant Campylobacter continue to be found on commercial poultry meat products over half a decade after the ban.”—In the U.S., antibiotics are introduced into the feed and water of industrially raised poultry, primarily to make them grow faster, rather than to treat disease. An estimated 13.2 million kg of antibiotics were sold in 2009 to the U.S. poultry and livestock industries, which represented nearly 80 percent of all antibiotic sales for use in humans and animals in the U.S. that year.—In conducting the study, researchers from the Johns Hopkins Bloomberg School of Public Health and Arizona State University analyzed commercially available feather meal samples, acquired from six U.S. states and China, for a suite of 59 pharmaceuticals and personal care products. All 12 samples tested had between 2 and 10 antibiotic residues. In addition to antimicrobials, 7 other personal care products, including the pain reliever acetaminophen (the active ingredient in Tylenol), the antihistamine diphenhydramine (the active ingredient in Benadryl) and the antidepressant fluoxetine (the active ingredient in Prozac), were detected.—Researchers also found caffeine in 10 of 12 feather meal samples. “This study reveals yet another pathway of unwanted human exposure to a surprisingly broad spectrum of prescription and over the-counter drugs,” noted study co-author Rolf Halden, PhD, PE, Co-Director of the Center for Health Information & Research, and Associate Director of the Swette Center for Environmental Biotechnology at Arizona State University.—When researchers exposed several strains of E. coli bacteria to the concentrations of antibiotics found in the feather meal samples, they also discovered the drug residues could select for resistant bacteria. “A high enough concentration was found in one of the samples to select for bacteria that are resistant to drugs important to treat infections in humans,” noted Nachman.—“We strongly believe that the FDA should monitor what drugs are going into animal feed,” urged Nachman. “Based on what we’ve learned, I’m concerned that the new FDA guidance documents, which call for voluntary action from industry, will be ineffectual. By looking into feather meal, and uncovering a drug banned nearly 6 years ago, we have very little confidence that the food animal production industry can be left to regulate it-self.”–Story Source-The above story is reprinted from materials provided by Johns Hopkins University Bloomberg School of Public Health, via Newswise.

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    Supplementation with Pycnogenol® improves signs and symptoms of menopausal transition.

    Panminerva Med. 2011 Sep;53(3 Suppl 1):65-70–Authors: Errichi S, Bottari A, Belcaro G, Cesarone MR, Hosoi M, Cornelli U, Dugall M, Ledda A, Feragalli B

    Abstract—AIM: The aim of this study was to evaluate the efficacy of Pycnogenol® standardized pine bark extract for alleviation of signs and symptoms associated with menopausal transition.
    METHODS: Pycnogenol® was used by 38 women as daily supplement in a dosage of 100 mg over an eight week period and menopausal symptoms were evaluated by means of a scoring system, based on a total number of 33 common signs and symptoms. A parallel control group of 32 comparable women was also followed up for the same period. Pycnogenol® was well tolerated, no side effects were reported and the compliance was very good with 98.6% of tablets used as prescribed. A range of 33 menopausal symptoms were evaluated using a scoring system with values ranging from zero (absent) to maximum 4 (very serious). RESULTS: A subset of six most common symptoms comprising hot flushes, night sweats, mood swings, irregular periods, loss of libido and vaginal dryness showed a decrease from average 2.67/4 to 1.45/4 after 8 weeks supplementation with Pycnogenol®. The control group of women showed no change from initial average 2.72/4 to 2.73/4 after eight weeks. The improvement of symptoms was statistical significant compared to the control group. Further symptoms related to fatigue, sleeping disorders, concentration and memory problems, dizziness, depression and irritability all improved significantly with Pycnogenol® compared to baseline values but did not reach statistical significance compared to the control group of women. The sensation of pain related to headaches, breast pain, the feeling of “electric shocks”, tingling extremities, burning tongue and itchy skin all improved significantly after intake of Pycnogenol® for eight weeks compared to baseline. Specifically the sensation of “electric shocks” and digestive problems improved significantly with Pycnogenol® as compared to women in the control group. The presence of elevated oxidative stress in women was investigated measuring capillary blood plasma free radicals. Oxidative stress was significantly lowered after four weeks (P<0.05) and eight weeks (P<0.022) in the Pycnogenol® group while no significant changes were observed in the control group at any time.
    CONCLUSION: Pycnogenol® significantly contributed to reduce signs and symptoms associated with menopausal transitions in women investigated in this study. Furthermore, Pycnogenol® improved the quality of life of most women and these benefits may be at least in part attributed to decreased oxidative stress levels.—PMID: 22108479 [PubMed – indexed for MEDLINE]

    Recipe for pine bark /needle tea—Take pine bark or needles from the tree in spring time for increasing the hormonal uptake and in the fall to reduce and make teas out of them as you would any other tea or percolate them in a coffee pot and drink small increments through out the day

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    Inactivation of Giardia Cysts by Iodine with Special Reference to Globaline

    Corporate Author : ARMY NATICK RESEARCH DEVELOPMENT AND ENGINEERING CENTER MA

    Personal Author(s) : Powers, Edmund M.

    Report Date : APR 1991

    Handle / proxy Url : http://handle.dtic.mil/100.2/ADA234938

    Abstract : This review of the literature indicates that iodine is not completely effective in destroying Giardia especially in cold (3 to 15C) water. Cysticidal efficacy of iodine at a given concentration and temperature depends on contact time. The iodine tablet, Globaline, used by U.S. Military Forces since 1952, required 60 minutes at 15C, 30 minutes at 25C and 25 minutes at 45C for 100% destruction of Giardia cysts at residual iodine concentration of 10, 8, and 6 mg per liter, respectively. The time required at temperatures below 15C for Globaline tablets to destroy Giardia is not presently known. Based on the information presented in this review, two changes for Globaline are recommended: (1) reformulate Globaline tablets with an alkaline buffer and (2) increase the treatment time for one liter of water from 35 minutes to 60 minutes.

    Descriptors : *IODINE, WATER, TABLETS(CHEMICAL), ALKALINITY, BUFFERS, TIME

    Subject Categories : WATER POLLUTION AND CONTROL

    Distribution Statement : APPROVED FOR PUBLIC RELEASE

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    STERILIZATION ACTION OF CHLORINE AND IODINE ON BACTERIA AND VIRUSES IN WATER SYSTEMS

    Since neither infectious RNA nor DNA is affected, iodine as a disinfectant probably inactivates bacteria and viruses by the iodination of the appropriate protein component. The bactericidal action of iodine is complete within one minute of contact at 570C. The rate of inactivation is not materially reduced by high concentrations of iodide ion. The destruction of bacteria continues until all iodine is consumed or, in case of residual iodine, until all bacteria are destroyed. The minimum number of iodine molecules required to destroy one bacterium varies with the species. For H. influenzae it was calculated to be 1.5 x 10 molecules of iodine per c9ll. When bacteria are treated with iodine, the inorganic phosphate up-take and oxygen consumption by the cells immediately ceases. Bacterial cells reacted with radioiodine show very little in the cell fraction, indicating that most likely an oxidation of -SH groups rather than a substitution into tyrosyl moieties occurs. The inactivation of poliovirus and f 2 RNA bacteria virus by iodine is considerably inhibited by low levels of iodide ion concentration. At pH 6.0 or less iodine inactivation of f2 phage was incomplete. The rate of inactivation by iodine in the presence of iodide ion for the f 2 virus and its host E. coli is different. The difference most likely is due to the nature of The -iodine sensitive proteins involved. The virucidal properties of iodine in waters of low pH and high organic content could be inadequate regardless of the free iodine concentration when virus or viruses involved require iodination of tyrosine for inactivation. At the existing stage of the investigation on the mode of action of bromine on virus and cells, further work will be required to form definite conclusions. A general tentative summary is as follows: (I) Bacterial cells appear to be more resistant to bromine than the phage[U1]. (2) Bromine activity on cells and phage varies directly with the hydrogen ion concentration and temperature. (3) The presence of the bromide ion enhances phage and inhibits cell inactivation by bromine. (4) The activity of RNA harvested from bromine treated phage is less affected than the intact phage.

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    Diabetic Remedy—Here is a list of things we have seen work to remove people off the insulin and get back to being healthy

    The things we have given are bitter melon-cinnamon bark-neem-peppermint-ginseng-clove-juniper berries in a tea format 1:1 ratio in all of the tea—boiled and consumed several times a day ( 4-5 times 1-3 oz increments)—as well we gave alpha lipoic acid 200mgs and 500mgs of L carnitine which were very effective with the teas at lowering sugar—dietary changes have to be implemented since the GMO’s are some of the biggest contributors we have to minimize exposure to nil- especially the soy and canola and rice—all are out of the diet—following the protocol and making juices with dandelion-parsley and watercress –are as well an effective way to assist people in the restoration of the system and reduction of sugar as well—-remember to utilize enzymes to relieve the pancreas since it is damaged and this will lighten the load for the pancreas utilize them at every meal and 2 in between meals to get you ready for the next day

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    Artificial Bee Silk a Big Step Closer to Reality

    ScienceDaily (Mar. 3, 2010) — CSIRO scientist Dr Tara Sutherland and her team have achieved another important milestone in the international quest to artificially produce insect silk.–They have hand-drawn fine threads of honeybee silk from a ‘soup’ of silk proteins that they had produced transgenically.–These threads were as strong as threads drawn from the honeybee silk gland, a significant step towards development of coiled coil silk biomaterials.—“It means that we can now seriously consider the uses to which these biomimetic materials can be put,” Dr Sutherland said.”We used recombinant cells of bacterium E. coli to produce the silk proteins which, under the right conditions, self-assembled into similar structures to those in honeybee silk.–“We already knew that honeybee silk fibres could be hand-drawn from the contents of the silk gland so used this knowledge to hand-draw fibres from a sufficiently concentrated and viscous mixture of the recombinant silk proteins.–“In fact, we had to draw them twice to produce a translucent stable fibre.”–Dr Sutherland said numerous efforts have been made to express other invertebrate silks in transgenic systems but the complicated structure of the silk genes in other organisms means that producing silk outside silk glands is very difficult.—“We had previously identified the honeybee silk genes and knew that that the silk was encoded by four small non-repetitive genes — a much simpler arrangement which made them excellent candidates for transgenic silk production.”–Possible practical uses for these silks would be tough, lightweight textiles, high-strength applications such as advanced composites for use in aviation and marine environments, and medical applications such as sutures, artificial tendons and ligaments.[U2]–Story Source-The above story is reprinted from materials provided by CSIRO Australia. –Journal Reference-Weisman et al. Honeybee silk: Recombinant protein production, assembly and fiber spinning. Biomaterials, 2010; 31 (9): 2695 DOI: 10.1016/j.biomaterials.2009.12.021

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    Sunlight Plus Lime Juice Makes Drinking Water Safer

    ScienceDaily (Apr. 17, 2012) — Looking for an inexpensive and effective way to quickly improve the quality of your drinking water? According to a team of researchers from the Johns Hopkins Bloomberg School of Public Health and the Johns Hopkins School of Medicine, sunlight and a twist of lime might do the trick. Researchers found that adding lime juice to water that is treated with a solar disinfection method removed detectable levels of harmful bacteria such as Escherichia coli (E. coli) significantly faster than solar disinfection alone.—The results are featured in the April 2012 issue of American Journal of Tropical Medicine and Hygiene.–“For many countries, access to clean drinking water is still a major concern. Previous studies estimate that globally, half of all hospital beds are occupied by people suffering from a water-related illness,” said Kellogg Schwab, PhD, MS, senior author of the study, director of the Johns Hopkins University Global Water Program and a professor with the Bloomberg School’s Department of Environmental Health Sciences. “The preliminary results of this study show solar disinfection of water combined with citrus could be effective at greatly reducing E. coli levels in just 30 minutes, a treatment time on par with boiling and other household water treatment methods. In addition, the 30 milliliters of juice per 2 liters of water amounts to about one-half Persian lime per bottle, a quantity that will likely not be prohibitively expensive or create an unpleasant flavor.”[U3]—In low-income regions, solar disinfection of water is one of several household water treatment methods to effectively reduce the incidence of diarrheal illness. One method of using sunlight to disinfect water that is recommended by the United Nations Children’s Fund (UNICEF) is known as SODIS (Solar water Disinfection). The SODIS method requires filling 1 or 2 L polyethylene terephthalate (PET plastic) bottles with water and then exposing them to sunlight for at least 6 hours[U4]. In cloudy weather, longer exposure times of up to 48 hours may be necessary to achieve adequate disinfection. To determine if one of the active constituents in limes known as psoralenes could enhance solar disinfection of water, Schwab and Alexander Harding, lead author of the study and a medical student at the Johns Hopkins School of Medicine, looked at microbial reductions after exposure to both sunlight and simulated sunlight. The researchers filled PET plastic bottles with dechlorinated tap water and then added lime juice, lime slurry, or synthetic psoralen and either E. coli, MS2 bacteriophage or murine norovirus. Researchers found that lower levels of both E. coli and MS2 bacteriophage were statistically significant following solar disinfection when either lime juice or lime slurry was added to the water compared to solar disinfection alone. They did find however, that noroviruses were not dramatically reduced using this technique, indicating it is not a perfect solution.–“Many cultures already practice treatment with citrus juice, perhaps indicating that this treatment method will be more appealing to potential SODIS users than other additives such as TiO2 [titanium dioxide] or H2O2[hydrogen peroxide],” suggest the authors of the study. However, they caution, “additional research should be done to evaluate the use of lemon or other acidic fruits, as Persian limes may be difficult to obtain in certain regions.”–The research was supported in part by the Osprey Foundation of Maryland, The Johns Hopkins University Global Water Program, the Johns Hopkins University School of Medicine Dean’s Funding for Summer Research and the Johns Hopkins University School of Medicine Scholarly Concentrations.Story Source–The above story is reprinted from materials provided by Johns Hopkins University Bloomberg School of Public Health. –Journal Reference–A. S. Harding, K. J. Schwab. Using Limes and Synthetic Psoralens to Enhance Solar Disinfection of Water (SODIS): A Laboratory Evaluation with Norovirus, Escherichia coli, and MS2. American Journal of Tropical Medicine and Hygiene, 2012; 86 (4): 566 DOI: 10.4269/ajtmh.2012.11-0370

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    [U1]A bacteriophage (from ‘bacteria’ and Greek φαγεῖν phagein “to devour”) is any one of a number of viruses that infect bacteria
    [U2]Always a reason for the violation of genetics —a good cause to treat and do something when they already have a more normal means of achievigng this
    [U3]30 mils- 1 oz+ — 2 litres = 33 oz
    [U4]Do it in Glass not this —this will leach eventually xeno estrogens into the body causing endocrine disrupting effects-that may lead to cancer
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    Show Of The Week April 23 2012

     

    How to apply the iodine to get the desired results

    Table. Summary of Disinfection Capabilities of Iodine Solutions and Resins.

    Joint Failures Potentially Linked to Oral Bacteria

    Lead Dust Is Linked to Violence

    Recipe for Removing Lead

     

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    How to apply the iodine to get the desired results

    Iodine is an effective disinfectant for viruses, bacteria, and many cysts at IWPD manufacturer recommended iodine dosages and contact times. In general, iodine is most effective against bacteria, followed by viruses. Iodine is least effective against cysts. Iodine is not an effective disinfectant against Cryptosporidium parvum oocysts (references 2, 3, 15 and16). Most manufacturers of iodine solution IWPDs recommend dosages between 4 and 16 mg/L with contact times ranging from 20 – 35 minutes, resulting in CTs of 80 – 560 mg-min/L. CT is the

    product of disinfectant concentration (C in mg/L) and contact time (T in min). The CT product-is a useful way for comparing alternative disinfectants and the resistance of various pathogens (reference 26). Because cysts are most resistant, dosages and contact times will be based on

    inactivation of cysts and CTs will be in the high-end of the 80 – 560 mg-min/L CT range. Compared to other disinfectants such as chlorine and chloramines, iodine reacts less with organic compounds, is less soluble, is least hydrolyzed in water, and is effective over the pH range likely

    encountered in natural water sources likely to be treated with an IWPD (references 2, 3 and 17). Together, these characteristics mean that low iodine residuals will persist longer, be more stable, and exert less of a demand in the presence of organic matter compared to chlorine and

    chloramines (reference 12). It has been established that only iodine and hypoiodous acid are capable of biocidal activity. The other iodine species are not effective biocides (references 3, 11, 12 and 16). For these reasons only iodine and hypoiodous acid are the iodine species considered in this paper.

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    In general, the pH of most natural water sources is neutral to mildly acidic, which is within the effective range for chemical disinfectants used for drinking water, including iodine solutions (reference 3). Iodine and hypoiodous acid have varying degrees of biocidal effectiveness against various pathogens. Iodine is up to three times more cysticidal and 6 times more sporocidal than hypoiodous acid (reference 3). Hypoiodous acid, on the other hand, is 40 times more virucidal and up to 4 times more bactericidal than iodine (reference 3). Because the concentration of these iodine species is dependent upon pH and initial iodine dose (see Figure), the following generalizations can be made. Iodine solutions are more effective cysticides and poorer virucides and bactericides at mildly acidic pH levels (< pH 7). Iodine solutions are more effective virucides and bactericides and poorer cysticides at alkaline pH levels (> pH 7). And, because it generally takes much longer to inactivate cysts than bacteria and viruses, iodine solutions used as IWPDs would be most effective at near neutral to mildly alkaline pH levels. However, at pH levels above 8, biocidal capability may drop sharply because HOI becomes unstable and decomposes to iodate and iodide, which are not effective biocides (see iodine chemistry above). To use iodine most effectively as a disinfectant, the pH should be near neutral to mildly alkaline to allow adequate levels of both iodine and hypoiodous acid (reference 4).

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    In general, colder water temperatures reduce the disinfection capability of iodine solutions and other chemical disinfectants (references 9, 17 and 21). Cold water temperatures slow disinfection and must be compensated for by longer contact time or higher concentration to achieve comparable disinfection at warmer water temperatures (reference 3). A 2 to 3-fold increase in inactivation rates per 10° C water temperature increase seems a generally accepted rule (reference 3). Studies have shown a significant impact on iodine disinfection capability by temperature. One study showed CT’s to provide 2-log inactivation of the E. Coli bacteria were 2-9 times higher in colder waters (2-5° C) than in warmer waters of 20-25° C (references 9 and 22). Another study showed a CT 3 times higher was necessary at a 3° C water temperature (CT = 200 mg-min/L) compared to 23° C water temperature (CT = 65 mg-min/L) for a 2-log inactivation of E. histolytica cysts (references 9 and 10). Another study using Giardia cysts showed CT’s up to 3 times higher in 3° C water resulted in only a 1.5-log inactivation compared to CT’s at 20° C which resulted in > 2.7-log inactivation (references 7 and 21). These studies show temperature has a significant effect on iodine disinfection capability. Longer contact times and/or higher iodine doses (i.e., increased CT’s) are necessary in colder waters. Using a 2-fold CT increase for every 10° C decrease in water temperature is a good estimate to use when determining CT requirements for iodine disinfection capability.

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    Bactericidal

    Numerous studies indicate iodine is an effective bactericide over the range of temperature and pH expected in natural water sources (references 9, 10, 22 and 27). Very low CT levels, ranging from 0.4 – 2.4 mg-min/L are required to inactivate 2-logs of E. Coli over a wide pH range (6 – 9) and temperature range (2 – 37° C) (reference 9). CT’s of less than 10 mg-min/L resulted in a 4- log inactivation of E. Coli at a near neutral pH (6 – 7) and extreme temperatures (~ 0 – 37° C) (references 9 and 27). These low CT’s translate into low iodine residuals and/or short contact times. For example, assuming a contact time of 20 minutes, a 0.5 mg/L iodine residual would be necessary to provide 4-log inactivation of E. Coli at near neutral pH at any temperature encountered in natural waters (20 min x 0.5 mg/L = 10 mg-min/L). When iodine solutions are used at typical doses for emergency drinking water disinfection (4 – 16 mg/L) and typical recommended contact times (20 – 35 minutes), the resulting CT’s of 80 – 560 mg-min/L would likely ensure a 6-log inactivation of bacteria.

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    Viricidal

    Several studies also show that iodine solutions are effective virucides (references 9, 10 and 27). Viruses are more resistant to iodine disinfection than bacteria, typically requiring higher CT’s than bacteria and in some cases much higher CT’s at low pH levels (e.g., 4 – 5), where hypoiodous acid (HOI) is not present, and at cold water temperatures (e.g., 5° C) (reference 9). Most studies evaluated the virucidal efficacy of iodine solutions against f2 virus and Poliovirus. Data indicate 2-log inactivation at near neutral to alkaline pH levels (6 – 10) and various water temperatures (5 – 30° C) occurred at CT’s of 15 – 75 mg-min/L with the higher CTs occurring at lower pH levels and colder water temperatures. One study showed a CT of less than 10 mg min/ L resulted in a 4-log inactivation of f2 virus at a pH of 7 and a very warm water temperature of 37° C (reference 9). Iodine solutions will likely provide a 4-log inactivation of viruses under most natural water conditions expected. Because IWPD dosages and contact times will be based on cyst inactivation, and resulting CTs will be large (80 – 560 mg-min/L), it is likely an IWPD will achieve 4-log virus inactivation under most water quality conditions.

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    Table. Summary of Disinfection Capabilities of Iodine Solutions and Resins.

    Parameter Iodine

    General

     

     

     

     

    Bacteria

     

    Viruses

     

     

    Giardia Cysts

     

     

     

     

     

    Cryptosporidium Oocysts

     

     

     

    Effect of Temperature

     

     

     

     

     

    Effect of pH

     

     

     

     

    Effect of Turbidity

     

     

    Solutions Iodine

    Cysts most resistant. Achieving Giardia cyst inactivation will ensure adequate bacteria and virusinactivation.

     

     

    Effective

     

    Effective

     

    Provide additional contact time beyond IWPD manufacturer recommended CTs.

     

     

     

     

     

    Not effective.

     

     

    Major effect. Increase contact time and/or dose at colder temperatures. CT’s up to 720 mg-min/L recommended for Giardia cyst inactivation in colder waters.

     

     

    Minor effect. Generally effective over typical pH levels for natural waters

     

     

    Affects disinfection capability. Provide additional contact time and/or increase iodine dose in more turbid waters.

    Iodine Resins

    Cysts most resistant. Achieving Giardia cyst inactivation will ensure adequate bacteria and virus inactivation

     

     

    Effective

     

    Effective

     

    Pentaiodide resin effective.

     

     

     

     

     

     

    Triiodide resin not effective. Provide additional contact time after passing through resin. Not effective.

    Major effect. Increase contact time after passing through pentaiodide resin at colder temperatures. Allow up to 40 minutes additional contact time for Giardia cysts inactivation in colder waters (< 5° C)

     

     

    Minor effect. Generally effective over pH range typical for natural waters

     

     

    Affects disinfection capability. Heavy organic matter loading can significantly reduce disinfection capability.

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    Joint Failures Potentially Linked to Oral Bacteria

    ScienceDaily (Apr. 18, 2012) — The culprit behind a failed hip or knee replacements might be found in the mouth. DNA testing of bacteria from the fluid that lubricates hip and knee joints had bacteria with the same DNA as the plaque from patients with gum disease and in need of a joint replacement. This study is one of many coming from the Case Western Reserve University School of Dental Medicine that have linked oral bacteria to health problems when they escape from the mouth and enter the blood. Working with University Hospitals Case Medical Center researchers, the dental, orthopedic and arthritis researchers suggest it might be the reason why aseptic loosening or prosthetic wear of the artificial joints fail within 10 years when no infection appears to be present. The pilot study’s findings were reported in the April issue of the Journal of Clinical Rheumatology. Dr. Nabil Bissada, chair of the Department of Periodontics at the dental school, said the objective of the study, “Identification of Oral Bacterial DNA in Synovial Fluid of Patients with Arthritis with Native and Failed Prosthetic Joints,” was to see if bacteria like Fusobacterium nucleatum and Serratia proteamaculans found in patients with gum disease were present in the fluid.–“For a long time, we’ve suspected that these bacteria were causing problems in arthritis patients, but never had the scientific evidence to support it,” Bissada says.–The researchers recruited and studied 36 patients seeking care at the University Hospitals Case Medical Center for osteoarthritis (the wearing of the joints) and rheumatoid arthritis (an autoimmune disease). -These study participants had both natural and artificial joints. Researcher extracted samples of their synovial fluid, which is much like oil that keeps a door from squeaking. These patients also had signs of periodontitis or gum disease and undergone exams where dental plaque was obtained for the study. Plaque build-up from the bacteria, associated with gum disease, breaks down the walls of the pockets around the teeth. The inflammation process from the bacteria acts like a gate that gives bacteria access to the blood stream. Once in the blood, the oral bacteria have induced inflammation in remote sites where the bacteria has been linked to heart, kidney and cancer diseases and premature births and fetal deaths.—Because these bacteria cannot be found with routine lab tests, detection of bacteria in the plaque and fluid was done through a process called polymerase chain reactions and DNA sequence analysis of specific genes (16S-23S rRNA). This is a sophisticated DNA tracking procedure.—-Five of the 36 patients (14%) showed direct DNA links between the bacteria in the fluid and plaque from the mouth. The breakdown in patients was: one from a rheumatoid arthritis (RA)[U1] patient with a failed natural joint and one RA patient with a failed replacement joint; two osteoarthritis (OA) patients with failed artificial joints and one OA patient with a failed natural joint.—Bissada said researchers will continue exploring the oral health link in a larger study. “We have a link now and want to see just how much of a trend this is. We also will be able to see if treating the periodontal disease, can reduce the number of future costly joint replacements.”—Collaborating with Bissada on the National Institutes of Health and Department of Periodontics-funded research were: Stephanie Temoin, Alia Chakaki, Ahmed El-Halaby, Yiping Han from the Case Western Reserve dental school, and Ali Askari, Steven Fitzgerald and Randall E. Marcus from University Hospitals Case –Story Source–The above story is reprinted from materials provided by Case Western Reserve University. –Journal Reference-Témoin, Stéphanie; Chakaki, Alia; Askari, Ali; El-Halaby, Ahmed; Fitzgerald, Steven; Marcus, Randall E.; Han, Yiping W.; Bissada, Nabil F. Identification of Oral Bacterial DNA in Synovial Fluid of Patients With Arthritis With Native and Failed Prosthetic Joints. Journal of Clinical Rheumatology, 18(3):117-121, April 2012 DOI: 10.1097/RHU.0b013e3182500c95

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    Lead Dust Is Linked to Violence

    Vehicles using leaded gasoline that contaminated cities’ air decades ago have increased aggravated assault in urban areas, researchers say. –ScienceDaily (Apr. 17, 2012) — Childhood exposure to lead dust has been linked to lasting physical and behavioral effects, and now lead dust from vehicles using leaded gasoline has been linked to instances of aggravated assault two decades after exposure, says Tulane toxicologist Howard W. Mielke.–Vehicles using leaded gasoline that contaminated cities’ air decades ago have increased aggravated assault in urban areas, researchers say.–The new findings are published in the journal Environment International by Mielke, a research professor in the Department of Pharmacology at the Tulane University School of Medicine, and demographer Sammy Zahran at the Center for Disaster and Risk Analysis at Colorado State University.—The researchers compared the amount of lead released in six cities: Atlanta, Chicago, Indianapolis, Minneapolis, New Orleans and San Diego, during the years 1950-1985. This period saw an increase in airborne lead dust exposure due to the use of leaded gasoline. There were correlating spikes in the rates of aggravated assault approximately two decades later, after the exposed children grew up.–After controlling for other possible causes such as community and household income, education, policing effort and incarceration rates, Mielke and Zahran found that for every one percent increase in tonnages of environmental lead released 22 years earlier, the present rate of aggravated assault was raised by 0.46 percent.—“Children are extremely sensitive to lead dust, and lead exposure has latent neuroanatomical effects that severely impact future societal behavior and welfare,” says Mielke. “Up to 90 per cent of the variation in aggravated assault across the cities is explained by the amount of lead dust released 22 years earlier.” Tons of lead dust were released between 1950 and 1985 in urban areas by vehicles using leaded gasoline, and improper handling of lead-based paint also has contributed to contamination.Story Source-The above story is reprinted from materials provided by Tulane University, via Newswise. –Journal Reference-Howard W. Mielke, Sammy Zahran. The urban rise and fall of air lead (Pb) and the latent surge and retreat of societal violence. Environment International, 2012; 43: 48 DOI: 10.1016/j.envint.2012.03.005

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    Recipe for Removing Lead—Apply Vitamin C 1000mgs + NAC ( or any sulfur based Supplement such as MSM 1000mgs-Methionine 1000mgs-alpha lipoic acid 200mgs—Kyolic formula 108 / 100/106 1000mgs ) and B1 ( thiamine 100 mgs 3 times a day-benfotiamine 100 mgs 3-4 times a day ( better choice ) or sulbatiamine 100 mgs 1-3 a day ) Use all of them together 3-4 times a day and avoid any re exposure

    Combining pectin from citrus or apple with onion as a mush will pull it out of the colon—

    Combining Iodine ( high dose 900mgs ) and selenium will remove this as well

    TOP F

    [U1]Is this interesting that Iodine and Turpentine kill off bacteria and Heal RA
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    Show Of The Week April 27 2012

    Monsanto-Free Seed Companies
    Fundamental Discovery Casts Enzymes in New Light

    New Process Improves Catalytic Rate of Enzymes by 3,000 Percent

    The efficacy of a single pocket irrigation on subgingival microbial vitality

    Pediatric Iodine –Safe Antibacterial, Antiviral & Antifungal for Children

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    Monsanto-Free Seed Companies
    Here are some seed companies. Please let us know of any we missed and we will add them to this list.

    All Good Things Organic
    Amishland Seeds
    Annapolis Valley Heritage Seed Company canada
    Baker Creek Seed Co.
    Botanical Interests
    Bountiful Gardens
    Diane’s Flower Seeds (she has veggies now, too)
    Fedco Seed Co. – phasing out seminis seeds.
    Fisher’s Seeds – 406-388-6052 They don’t have a website, but they will send you a catalog if you give them your address
    PO Box 236, Belgrade, MT 59714
    Garden City Seeds
    Gourmet Seed
    Heirlooms Evermore Seeds
    Heirloom Seeds
    High Mowing Seeds
    Horizon Herbs
    Hudson Valley Seed Library
    Humbleseeds
    Irish-Eyes
    J.L Hudson
    Kitchen Garden Seeds
    Kusa Seed Society
    Lake Valley Seeds
    Landreth Seeds
    Livingston Seeds
    Local Harvest
    Mountain Rose Herbs
    Native Seeds for the Arid Southwest
    Natural Gardening Company
    New Hope Seed Company
    Nichol’s Garden Nursery
    Organica Seed
    Peace Seeds
    Peaceful Valley Farm Supply
    Pinetree
    Renee’s Garden
    Richters Herbs
    Sand Hill Preservation Center
    Seed Saver’s Exchange
    Seeds of Change
    Southern Exposure
    Sow True
    Tiny Seeds
    Tomato Fest
    Trees of Antiquity
    Turtle Tree Seed
    Underwood Garden Seeds
    Uprising Seeds
    Victory Seeds
    Wild Garden Seeds
    Wildseed Farms
    Wood Prairie Farm

    Canadian Seed Companies:

    Salt Spring Seeds
    Seeds of Victoria
    Solana Seeds
    Terra Edibles
    The Cottage Gardener
    West Coast Seeds
    Sources: http://www.manytracks.com/Garden/IndieSeedCompanies.htm

    http://www.treehugger.com/lawn-garden/10-best-seed-companies-selected-by-readers.html

    Source: http://www.occupymonsanto360.org (http://s.tt/18OFq)

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    Fundamental Discovery Casts Enzymes in New Light

    ScienceDaily (Nov. 9, 2011) — A tree outside Oak Ridge National Laboratory researcher Pratul Agarwal’s office window provided the inspiration for a discovery that may ultimately lead to drugs with fewer side effects, less expensive biofuels and more.—-Just as a breeze causes leaves, branches and ultimately the tree to move, enzymes moving at the molecular level perform hundreds of chemical processes that have a ripple effect necessary for life. Previously, protein complexes were viewed as static entities with biological function understood in terms of direct interactions, but that isn’t the case. This finding, recently published in PLoS Biology, may have enormous implications.–“Our discovery is allowing us to perhaps find the knobs that we can use to improve the catalytic rate of enzymes and perform a host of functions more efficiently,” said Agarwal, a member of the Department of Energy laboratory’s Computer Science and Mathematics Division.–Making this discovery possible was ORNL’s supercomputer, Jaguar, which allowed Agarwal and co-author Arvind Ramanathan to investigate a large number of enzymes at the atomistic scale.—The researchers found that enzymes have similar features that are entirely preserved from the smallest living organism — bacteria — to complex life forms, including humans.-“If something is important for function, then it will be present in the protein performing the same function across different species[U1],” Agarwal said. “For example, regardless of which company makes a car, they all have wheels and brakes.”–Similarly, scientists have known for decades that certain structural features of the enzyme are also preserved because of their important function. Agarwal and Ramanathan believe the same is true for enzyme flexibility.–“The importance of the structure of enzymes has been known for more than 100 years, but only recently have we started to understand that the internal motions may be the missing piece of the puzzle to understand how enzymes work,” Agarwal said. “If we think of the tree as the model, the protein move at the molecular level with the side-chain and residues being the leaves and the protein backbone being the entire stem.”—This research builds on previous work in which Agarwal identified a network of protein vibrations in the enzyme Cyclphilin A, which is involved in many biological reactions, including AIDS-causing HIV-1.—While Agarwal sees this research perhaps leading to medicines able to target hard to cure diseases such as AIDS, he is also excited about its energy applications, specifically in the area of cellulosic ethanol. Highly efficient enzymes could bring down the cost of biofuels, making them a more attractive option.—Funding for this research was provided by ORNL’s Laboratory Directed Research and Development program. Ramanathan was a graduate student at Carnegie Mellon University when this work began and now also works at ORNL. The paper is titled “Evolutionarily conserved linkage between enzyme fold, flexibility and catalysis.”–Story Source-The above story is reprinted from materials provided by DOE/Oak Ridge National Laboratory. –Journal Reference-Arvind Ramanathan, Pratul K. Agarwal. Evolutionarily Conserved Linkage between Enzyme Fold, Flexibility, and Catalysis. PLoS Biology, 2011; 9 (11): e1001193 DOI: 10.1371/journal.pbio.1001193

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    New Process Improves Catalytic Rate of Enzymes by 3,000 Percent

    ScienceDaily (Apr. 17, 2012) — Light of specific wavelengths can be used to boost an enzyme’s function by as much as 30 fold, potentially establishing a path to less expensive biofuels, detergents and a host of other products.–In a paper published in The Journal of Physical Chemistry Letters, a team led by Pratul Agarwal of the Department of Energy’s Oak Ridge National Laboratory described a process that aims to improve upon nature — and it happens in the blink of an eye.—“When light enters the eye and hits the pigment known as rhodopsin, it causes a complex chemical reaction to occur, including a conformational change,” Agarwal said. “This change is detected by the associated protein and through a rather involved chain of reactions is converted into an electrical signal for the brain.”—With this as a model, Agarwal’s team theorized that it should be possible to improve the catalytic efficiency of enzyme reactions by attaching chemical elements on the surface of an enzyme and manipulating them with the use of tuned light.—The researchers introduced a light-activated molecular switch across two regions of the enzyme Candida antarctica lipase B, or CALB — which breaks down fat molecules — identified through modeling performed on DOE’s Jaguar supercomputer.–“Using this approach, our preliminary work with CALB suggested that such a technique of introducing a compound that undergoes a light-inducible conformational change onto the surface of the protein could be used to manipulate enzyme reaction,” Agarwal said.—While the researchers obtained final laboratory results at industry partner AthenaES, computational modeling allowed Agarwal to test thousands of combinations of enzyme sites, modification chemistry, different wavelengths of light, different temperatures and photo-activated switches. Simulations performed on Jaguar also allowed researchers to better understand how the enzyme’s internal motions control the catalytic activity.—“This modeling was very important as it helped us identify regions of the enzyme that were modified by interactions with chemicals,” said Agarwal, a member of ORNL’s Computer Science and Mathematics Division. “Ultimately, the modeling helped us understand how the mechanical energy from the surface can eventually be transferred to the active site where it is used to conduct the chemical reaction.”—Agarwal noted that enzymes are present in every organism and are widely used in industry as catalysts in the production of biofuels and countless other every day products. Researchers believe this finding could have immense potential for improving enzyme efficiency, especially as it relates to biofuels.–Funding for this work was provided by Technology Maturation Funds from Battelle Memorial Institute. Story Source-The above story is reprinted from materials provided by DOE/Oak Ridge National Laboratory. –Journal Reference–Pratul K. Agarwal, Christopher Schultz, Aristotle Kalivretenos, Brahma Ghosh, Sheldon E. Broedel. Engineering a Hyper-catalytic Enzyme by Photoactivated Conformation Modulation. The Journal of Physical Chemistry Letters, 2012; : 1142 DOI: 10.1021/jz201675m

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    The efficacy of a single pocket irrigation on subgingival microbial vitality.

    von Ohler C, Weiger R, Decker E, Schlagenhauf U, Brecx M.

    Source-Department of Periodontology and Conservative Dentistry, University of the Saarland, Gebäude 73, D-66421 Homburg/Saar, Germany.

    Abstract

    The object of this study was to monitor the proportion of vital bacteria (microbial vitality: VF in %) present in subgingival dental plaque following one single subgingival irrigation with saline (S), chlorhexidine (CHX) or povidone iodine (I2), but without any subgingival instrumentation. Its effect on the main composition of the microflora was also assessed. Seventeen patients with adult periodontitis took part in this investigation. In each patient four initially untreated pockets (pocket depth 5-11 mm) associated with bleeding were selected for the standardised pocket irrigation and plaque sampling at baseline (0 h) and after the following 1 h, 24 h, 7 days and 31 days. The subgingival irrigation was only performed once (0 h). One pocket per quadrant was irrigated using 0.9% prereduced S, 0.2% CHX or 0.05% I2 (Iso-Betadine Buccale). The remaining untreated pocket without any irrigation served as an additional control (C). Using an acrylic splint as a guide, paperpoints were inserted into the pocket precisely at the same site to collect subgingival plaque. The bleeding on sampling (BOS) was thereafter noted. The proportions of bacterial morphotypes were examined by darkfield microscopy. VF was evaluated using a vital fluorescence staining. The undisturbed subgingival dental plaque was composed of 86% (median value) vital bacteria. The sampling procedure alone and the saline irrigation led to a decrease in the number of spirochetes but had no influence on the vitality of the flora. Large variations in VF could be observed in the short-term (1 h, 24 h) irrigation effect of CHX and I2. The reduction of VF was still significant after 7 days (VF(CHX) 30-80%, VF(I2) 35-80%) but persisted up to 31 days only after I2 irrigation (VF(I2) 12-90%). The findings indicated that all single subgingival irrigations resulted in a temporary change of the subgingival microflora while povidone iodine produced the longest lasting antimicrobial effect. Any clinical advantage of this situation should be further investigated.

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    [U1]Genetic manipulation with enzymes or even dna manipulation which our bodies do naturally but if something else is added –then you will have a effect
    [U2]And Selenium and Zinc the selenium to assist the iodine and to regulate the heart like magnesium
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    Show of the Week April 30-2012

    Therapeutic Uses of (Topically Applied) Salicylic Acid

    Recipe for Salicylic Acid

    Inhibitory effect of aqueous Dandelion extract on HIV-1 replication and reverse transcriptase activity

    Aspirin May Lower the Risk of Pancreatic Cancer

    Aspirin Reduces Cancer Risk: Is It Time to Include It in Cancer Prevention Guidelines?

    Regular Aspirin Intake Halves Cancer Risk, Study Finds

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    Therapeutic Uses of (Topically Applied) Salicylic Acid

    All of the topical uses of Salicylic Acid are based on its actions as a keratolytic agent (i.e. its ability to loosen the Stratum Corneum of the Epidermis of the Skin).

    Skin/Hair—-Salicylic Acid (diluted and applied topically) is sometimes used for the treatment of Acne (it “unplugs” blocked Sebaceous Glands via its exfoliant properties.).

    Salicylic Acid (in a 2 – 3% solution applied topically) may alleviate Dandruff (by causing the dead cells that comprise Dandruff to peel (shed)).

    Salicylic Acid (in a 2 – 6% solution applied topically) may alleviate Psoriasis (by causing the dead cells involved in Psoriasis to peel (shed)).

    Salicylic Acid (applied topically) may act as an exfoliant for the Skin – this action may improve the visual appearance of the Skin (the thinning of the superficial layer of the Skin results in smoother, more radiant Skin)

    -Salicylic Acid (applied topically) may remove almost all abnormal Skin Pigmentation, fine Wrinkles, precancerous lesions and Lipofuscin (Age Spots) – especially from the Skin of the hands and forearms.

    Salicylic Acid (applied topically by a dermatologist) is sometimes used as the peeling agent in Chemical Peels of the Skin.

    Salicylic Acid (10% solution applied topically) is sometimes prescribed for the treatment of Solar Keratoses.

    Salicylic Acid (applied topically in a solution of 10% – 70%) is often employed by dermatologists to remove Warts

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    Recipe for Salicylic —take TSP 3 parts to 1 part Salicylic Acid and 50 parts water—so take 3 grams of TSP-1 gram of Salicylic acid and 50 grams of water ( 2 oz )—this will increase it’s ability to be dissolved and utilized—this will be another way of making a pain remedy—make sure you if you use an aspirin that it is clean and without contamination—best place I have seen to buy this is at a horse supplier—

    Salicylic Acid For Skin Conditions -add 10 grams of Salicylic Acid to 100mls of alcohol and proceed to shake til dissolved – this will make a 10% solution to be dabbed on an area—to make a 2 percent then just add 2 grams to the 100mls

    100mls is 3 oz

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    Inhibitory effect of aqueous Dandelion extract on HIV-1 replication and reverse transcriptase activity.

    BMC Complement Altern Med. 2011;11:112—Authors: Han H, He W, Wang W, Gao B

    Abstract
    Human immunodeficiency virus (HIV), is an immunosuppressive disease that results in life-threatening opportunistic infections. The general problems in current therapy include the constant emergence of drug-resistant HIV strains, adverse side effects and the unavailability of treatments in developing countries. Natural products from herbs with the abilities to inhibit HIV-1 life cycle at different stages, have served as excellent sources of new anti-HIV-1 drugs. In this study, we aimed to investigate the anti-HIV-1 activity of aqueous dandelion extract.—ÃÃDandelion Tea or SoupÃÃ
    METHODS: The pseudotyped HIV-1 virus has been utilized to explore the anti-HIV-1 activity of dandelion, the level of HIV-1 replication was assessed by the percentage of GFP-positive cells. The inhibitory effect of the dandelion extract on reverse transcriptase activity was assessed by the reverse transcriptase assay kit. RESULTS: Compared to control values obtained from cells infected without treatment, the level of HIV-1 replication and reverse transcriptase activity were decreased in a dose-dependent manner. The data suggest that dandelion extract has a potent inhibitory activity against HIV-1 replication and reverse transcriptase activity. The identification of HIV-1 antiviral compounds from Taraxacum officinale should be pursued.
    CONCLUSIONS: The dandelion extract showed strong activity against HIV-1 RT and inhibited both the HIV-1 vector and the hybrid-MoMuLV/MoMuSV retrovirus replication. These findings provide additional support for the potential therapeutic efficacy of Taraxacum officinale. Extracts from this plant may be regarded as another starting point for the development of an antiretroviral therapy with fewer side effects.—PMID: 22078030 [PubMed – indexed for MEDLINE]

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    Aspirin May Lower the Risk of Pancreatic Cancer

    ScienceDaily (Apr. 4, 2011) — The use of aspirin at least once per month is associated with a significant decrease in pancreatic cancer risk, [U1]according to results of a large case-control study presented at the AACR 102nd Annual Meeting 2011, held in Orlando, Florida, April 2-6.—-Xiang-Lin Tan, –For the current study, Tan and colleagues enrolled 904 patients who had documented pancreatic cancer and compared them with 1,224 healthy patients. All patients were at least 55 years old and reported their use of aspirin, NSAIDs and acetaminophen by questionnaire.—Results showed that people who took aspirin at least one day during a month had a 26 percent decreased risk of pancreatic cancer compared to those who did not take aspirin regularly. The effect was also found for those who took low-dose aspirin for heart disease prevention at 35 percent lower risk, according to Tan.–The researchers did not see a benefit from non-aspirin NSAIDs or acetaminophen. “This provides additional evidence that aspirin may have chemoprevention activity against pancreatic cancer,” said Tan. He added that more data must be gathered before we can prove a real benefit.–Story Source-The above story is reprinted from materials provided by American Association for Cancer Research.

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    Aspirin Reduces Cancer Risk: Is It Time to Include It in Cancer Prevention Guidelines?

    ScienceDaily (Apr. 9, 2012) — A new report by American Cancer Society scientists says new data showing aspirin’s potential role in reducing the risk of cancer death bring us considerably closer to the time when cancer prevention can be included in clinical guidelines for the use of aspirin in preventative care. The report, published early online in Nature Reviews Clinical Oncology, says even a 10% reduction in overall cancer incidence beginning during the first 10 years of treatment could tip the balance of benefits and risks favorably in average-risk populations.—Current guidelines for the use of aspirin in disease prevention consider only its cardiovascular benefits, weighed against the potential harm from aspirin-induced bleeding. While daily aspirin use has also been convincingly shown to reduce the risk of colorectal cancer and recurrence of adenomatous polyps, these benefits alone do not outweigh harms from aspirin-induced bleeding in average-risk populations.[U2] But recently published secondary analyses of cardiovascular trials have provided the first randomized evidence that daily aspirin use may also reduce the incidence of all cancers combined, even at low doses (75-100 mg daily).—The current review, led by Michael J. Thun, M.D., vice president emeritus of epidemiology and surveillance research for the American Cancer Society was not designed as a comprehensive review of the literature, but instead is a focused discussion of the key outstanding issues in using aspirin as a cancer prevention tool.\The report says recently published meta-analyses of results from randomized trials of daily aspirin treatment to prevent vascular events have provided provocative evidence that daily aspirin at doses of 75 mg and above might lower both overall cancer incidence and overall cancer mortality.—In six primary prevention trials of daily low-dose aspirin, randomization to aspirin treatment was associated with an approximately 20% reduction in overall cancer incidence between 3 and 5 years after initiation of the intervention (metaodds ratio [OR] = 0.81; 95% CI 0.67-0.98) and a 30% reduction during follow up more than 5 years after randomization (meta-OR = 0.70; 95% CI 0.56-0.88). Cancer mortality was also reduced during study follow up that happened more than 5 years after the start of aspirin use (meta-OR = 0.63; 95% CI 0.49-0.82) in analyses that included 34 trials of daily aspirin at various doses. Surprisingly, the size of the observed benefit did not increase with daily doses of aspirin above 75-100 mg. Notably, these meta-analyses excluded results from the Women’s Health Study (WHS), a large 10-year-long trial of 100 mg of aspirin taken every other day, which reported no reduction in cancer incidence or mortality.—“The accumulating data from randomized clinical trials provide an exciting opportunity to reconsider the potential role of aspirin in cancer prevention,” write the authors. They say several important questions remain unanswered, such as the exact magnitude of the overall cancer benefit and which individual cancer sites contribute to this benefit. “However, these new data bring us considerably closer to the time when cancer prevention can be integrated into the clinical guidelines for prophylactic treatment following regulatory review by the FDA and the European Medicines Agency.”—Story Source—The above story is reprinted from materials provided by American Cancer Society. –Journal Reference-Michael J. Thun, Eric J. Jacobs, Carlo Patrono. The role of aspirin in cancer prevention. Nature Reviews Clinical Oncology, 2012; DOI: 10.1038/nrclinonc.2011.199

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    Regular Aspirin Intake Halves Cancer Risk, Study Finds

    ScienceDaily (Oct. 28, 2011) — Scientists including those from Queen’s University have discovered that taking regular aspirin halves the risk of developing hereditary cancers.—Hereditary cancers are those which develop as a result of a gene fault inherited from a parent. Bowel and womb cancers are the most common forms of hereditary cancers. Fifty thousand people in the UK are diagnosed with bowel and womb cancers every year; 10 per cent of these cancers are thought to be hereditary.—The decade-long study, which involved scientists and clinicians from 43 centres in 16 countries and was funded by Cancer Research UK, followed nearly 1,000 patients, in some cases for over 10 years. The study found that those who had been taking a regular dose of aspirin had 50 per cent fewer incidents of hereditary cancer compared with those who were not taking aspirin.—The research focused on people with Lynch syndrome which is an inherited genetic disorder that causes cancer by affecting genes responsible for detecting and repairing damage in the DNA. Around 50 per cent of those with Lynch syndrome develop cancer, mainly in the bowel and womb. The study looked at all cancers related to the syndrome, and found that almost 30 per cent of the patients not taking aspirin had developed a cancer compared to around 15 per cent of those taking the aspirin.—Those who had taken aspirin still developed the same number of polyps, which are thought to be precursors of cancer, as those who did not take aspirin but they did not go on to develop cancer. It suggests that aspirin could possibly be causing these cells to destruct before they turn cancerous.—Over 1,000 people were diagnosed with bowel cancer in Northern Ireland last year; 400 of these died from the disease. Ten per cent of bowel cancer cases are hereditary and by taking aspirin regularly the number of those dying from the hereditary form of the disease could be halved.—Professor Patrick Morrison from Queen’s University in Belfast, who led the Northern Ireland part of the study, said: “The results of this study, which has been ongoing for over a decade, proves that the regular intake of aspirin over a prolonged period halves the risk of developing hereditary cancers. The effects of aspirin in the first five years of the study were not clear but in those who took aspirin for between five and ten years the results were very clear.”—“This is a huge breakthrough in terms of cancer prevention. For those who have a history of hereditary cancers in their family, like bowel and womb cancers, this will be welcome news. Not only does it show we can reduce cancer rates and ultimately deaths, it opens up other avenues for further cancer prevention research. We aim now to go forward with another trial to assess the most effective dosage of aspirin for hereditary cancer prevention and to look at the use of aspirin in the general population as a way of reducing the risk of bowel cancer.–“For anyone considering taking aspirin I would recommend discussing this with your GP first as aspirin is known to bring with it a risk of stomach complaints, including ulcers.”—The research was published online Oct. 28 in The Lancet.–Story Source-The above story is reprinted from materials provided by Queen’s University Belfast. —Journal Reference-Sir John Burn, Anne-Marie Gerdes, Finlay Macrae, Jukka-Pekka Mecklin, Gabriela Moeslein, Sylviane Olschwang, Diane Eccles, Gareth Evans, Eamonn R. Maher, Lucio Bertario, Marie-Luise Bisgaard, Malcolm G. Dunlop, Judy W.C. Ho, Shirley V. Hodgson, Annika Lindblom, Jan Lubinski, Patrick J. Morrison, Victoria Murday, Raj Ramesar, Lucy Side, Rodney J. Scott, Huw J.W. Thomas, Hans F. Vasen, Gail Barker, Gillian Crawford, Faye Elliott, Mohammad Movahedi, Kirsi Pylvanainen, Juul T. Wijnen, Riccardo Fodde, Henry T. Lynch, John C. Mathers, D. Timothy Bishop, on behalf of the CAPP2 Investigators. Long-term effect of aspirin on cancer risk in carriers of hereditary colorectal cancer: an analysis from the CAPP2 randomised controlled trial. The Lancet, Pubished online Oct. 28, 2011; DOI: 10.1016/S0140-6736(11)61049-0

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    [U1]Make sure the aspirin in use or the Salicylic Acid does not have any contamination or colouring agents or plastics such as polyethylene glycol–
    [U2]The reason being is that they are not putting it together properly—should be mixed with a sodium phosphate or borax solution or with even magnesium to offset any negative side effects that the salcyclic acid may produce

    #351
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    Keymaster

    Herbal Oil Making— Take a herb of choice—rosemary for example—add ¼ cup of the rosemary and add 1 cup to a cup ¼ of alcohol—add both contents to a blender and blend at high speed for 10 minutes—Strain this and add to a pot—set the heat up to med-high range and add 1 tablespoon of water to it—allow it to boil out the excess water til it gets below half—then pour this into either a glass container or another container and put on top of either a metal plate over the burner or metal pot and allow it to further simmer down to a point where you see the oil—this will then be placed in a glass container—what you have done is concentrate the components of the herb into an oil utilizing this in drop amounts instead of high volume—so in this case all the properties of the rosemary are all super concentrated and will need considerably less—this will actually potentiate those components even more

     

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    Salicyclic Gel Making- Take a Salicyclic powder or use aspirin ( clean without additives) and powder it down and get TSP as well and water—what we are going to do is use this in this formulation 10 grams of salicyclic acid 30 grams of TSP and 2 0z of water ( or you can double it to make the solution more in volume—20 grams of the sal/60 grams of the TSP/ and 100 grams of water—once mixed and dissolved the you will add 20 drops of lugols ( 15%) if you only have 5-7% then triple the drops or double to make it as strong as you desire— add 1/ cup of aloe vera gel 0r juice add 1 tsp of xanthium gum ( more or less this is just a guideline) and citric acid 1 tsp ( again a guideline add more or less as you see fit )then add ¼ cup of the solution you just made and blend til thicken— when done pour into a glass container.

     

    Application—apply to areas of lesions and or wounds and will see a regeneration of the tissue or skin health—it will hydrate and disinfect an area and act like a bandaid in sealing and protecting from further exposure to pathogens—can be used for eczema and a germicidal—

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    Soy-Based Formula- Neonatal Plant Estrogen Exposure Leads to Adult Infertility in Female Mice

    ScienceDaily (May 2, 2012) — A paper published May 2 in Biology of Reproduction describes the effects of brief prenatal exposure to plant estrogens on the mouse oviduct, modeling the effects of soy-based baby formula on human infants. The results suggest that exposure to estrogenic chemicals in the womb or during childhood has the potential to affect a woman’s fertility as an adult, possibly providing the mechanistic basis for some cases of unexplained female infertility.[U1] Earlier research suggested that neonatal exposure to plant estrogens or other environmental estrogens (synthetic substances that function similarly to the estrogen naturally produced in the body) may have long- term effects on adult female reproductive health. Wendy N. Jefferson, a researcher in the lab of Carmen J. Williams at the National Institute of Environmental Health Sciences (NIEHS), part of the National Institutes of Health, previously demonstrated that neonatal exposure to the plant estrogen genistein results in complete infertility in female adult mice. Causes of infertility included failure to ovulate, reduced ability of the oviduct to support embryo development before implantation, and failure of the uterus to support effective implantation of blastocyst-stage embryos.—The team now reports that neonatal exposure to genistein changes the level of immune response in the mouse oviduct, known as mucosal immune response. Some of the immune response genes were altered beginning from the time of genistein treatment, while others were altered much later, when the mouse was in early pregnancy. Together, those changes led to harmfully altered immune responses and to compromised oviduct support for preimplantation embryo development, both of which would likely contribute to infertility.[U2]—These findings raise the possibility that exposure to low levels of environmental or plant estrogens during sensitive developmental windows can alter the balance of the mucosal immune response in the uterus and oviduct.[U3] In the mouse, the window of development during which these changes can occur is found only in the neonatal period; in humans, development of the reproductive tract continues through the onset of puberty. Therefore, estrogenic chemical exposure to the female fetus, infant, child, and adolescent all have potential impacts on mucosal immunity in the reproductive tract and, therefore, on adult fertility. The authors present the view that limiting such exposures, including minimizing use of soy-based baby formula, is a step toward maintaining female reproductive health.–Story Source-The above story is reprinted from materials provided by Society for the Study of Reproduction. –Journal Reference-Jefferson WN, Padilla-Banks E, Phelps JY, Cantor AM, Williams CJ. Neonatal phytoestrogen exposure alters oviduct mucosal immune response to pregnancy and affects preimplantation embryo development in the mouse. Biology of Reproduction, 2 May 2012 DOI: 10.1095/biolreprod.112.099846

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    Glycogen Accumulation in Neurons Causes Brain Damage and Shortens the Lives of Flies and Mice

    ScienceDaily (May 2, 2012) — Collaborative research by groups headed by scientists Joan J. Guinovart and Marco Milán at the Institute for Research in Biomedicine (IRB Barcelona) has revealed conclusive evidence about the harmful effects of the accumulation of glucose chains (glycogen) in fly and mouse neurons. These two animal models will allow scientists to address the genes involved in this harmful process and to find pharmacological solutions that allow disintegration of the accumulations or limitation of glycogen production.—Advances in this direction would make a significant contribution to investigation into Lafora progressive myoclonic epilepsy and other neurodegenerative diseases characterized by glycogen accumulation in neurons. The journal EMBO Molecular Medicine publishes the results of the study this week.—“Our data clearly indicate that glycogen accumulation alone kills neurons and thus dramatically reduces lifespan,” explains Guinovart, an expert in glycogen metabolism, group leader at IRB Barcelona, and senior professor at the University of Barcelona, “because the only thing we have manipulated in the neurons is their capacity to produce glycogen.”—The inclusion of the Drosophila fly in the study provides in vivo confirmation of the theory in another animal model as these flies also show the same symptoms of degeneration as mice when glycogen accumulates in neurons. However, in addition the use of Drosophila will speed upobtaining genetic data and the screening of therapeutic molecules. “In a short time we will be able to perform a massive search for genes involved in the pathological process and to understand it better at the molecular level,” emphasizes Marco Milán, ICREA researcher at IRB Barcelona and a specialist in Drosophila. “But the flies will also be useful to identify pharmacological molecules that can cure,” he explains.—The IRB Barcelona teams are designing several experiments to identify the possible therapeutic targets that may be useful to prevent glycogen accumulation in neurons. In addition to the direct relation to Lafora epilepsy, a progressive degenerative disease that affects adolescents and has no cure, glycogen accumulation could be the main cause of other neurodegenerative illnesses such as Adult polyglucosan body disease and Andersen’s disease.–Story Source–The above story is reprinted from materials provided by Institute for Research in Biomedicine-IRB, via AlphaGalileo. –Journal Reference–Jordi Duran, María Florencia Tevy, Mar Garcia-Rocha, Joaquim Calbó, Marco Milán, Joan J. Guinovart. Deleterious effects of neuronal accumulation of glycogen in flies and mice. EMBO Molecular Medicine, 2012; DOI: 10.1002/emmm.201200241

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    Pyritrinol—- benefits and Uses

    1. pyritinol reduced mortality in 100 coma patients
    2. pyritinol is beneficial in the treatment of head injury
    3. pyritinol rheumatoid arthritis study with pyritinol and auranofin
    4. pyritinol improved memory in a study of 12 healthy males
    5. pyritinol protects against free radical damage to cell proteins
    6. pyritinol improved cerebral glucose metabolism in dementia
    7. pyritinol produced significant improvement in 40 dementia patients
    8. pyritinol had therapeutic effect on 156 senile dementia patients
    9. pyritinol caused an increase of cGMP level in neutrophils
    10. pyritinol improved cognition in 100 dementia patients
    11. pyritinol study of 40 Alzheimer’s patients
    12. pyritinol and phosphatidylinositol metabolism in mouse brain
    13. pyritinol improved cognitive performance in 26 dementia patients
    14. pyritinol increased glucose utilisation in cerebellum of rats
    15. pyritinol improved social behavior in geriatric patients
    16. pyritinol improved learning retention in Swiss albino mice
    17. pyritinol in cerebral infarct patients

     

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    Enhanced Glucose Transport

    Pyritinol’s ability to enhance glucose transport through the blood-brain barrier when it is low is a highly significant benefit of Pyritinol. Although the brain is usually less than 2% of total bodyweight, the brain must produce and use about 20% – 500 calories per day – of the body’s total energy production. And under normal, non-fasting conditions, the brain can only ‘burn’ glucose (sugar) for fuel. Unlike virtually all other body cells, nerve cells cannot use fat as an energy fuel. Brain cells also cannot store any significant amount of glucose – they are completely dependent upon a continuous delivery of glucose from the blood, through the blood-brain barrier. Thus, brain glucose uptake is a major rate-limiting factor for crucial brain energy production. Low cerebral glucose uptake necessarily translates into low brain carbohydrate energy metabolism.–And brain energy metabolism is so important to optimal, healthy brain function that “… brain carbohydrate metabolism is impaired in a variety of dementias [e.g. Alzheimer’s, stroke, metabolic, or drug toxicity dementias] and … the degree of reduction in brain carbohydrate metabolism is correlated with the severity of the dementias ….” (7) Pyritinol is good for optimal brain carbohydrate metabolism , and what is good for brain carbohydrate metabolism is good for the brain and the mind!

     

     

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    [U1]UMMM don’t you just Love the diplomacy here—genistein and daizden are phyto estrogens the body does not recognize and causes mutated cells to take over –and causing further endocrimne disruptinig effects—and this is why some women have no sex drive or even men—the Agro Scientist have formulated a food to destroy the capability of reproduction—Sterilizing the human race
    [U2]BIRTH CONTROL and the damaging of the reproductive and endocrine Balance
    [U3]This would be key in reversing the damage to what was being fed

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    Show Of The Week May 7 2012

     

    Millions of Bees Mysteriously Die in Florida

    12 milion bees found dead in Florida and no one knows why!

    Higher Risk of Birth Defects from Assisted Reproduction

     

    Strengthening Foods For Fevers or in Weakness

     

    Menthol Suppresses Nicotinic Acetylcholine Receptor Functioning in Sensory Neurons via Allosteric Modulation

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    Millions of Bees Mysteriously Die in Florida

    MICCO, Fla. (CBS Tampa/AP) – Florida officials are abuzz as to how millions of honey bees were killed in Brevard County.—Several beekeepers in the county have reported lost colonies this week. Charles Smith of Smith Family Honey Company told Stuart News Thursday he lost 400 beehives. He says the bees appeared to have been poisoned.–“I’ll never get completely compensated for this unless someone handed me 400 beehives,” Smith told Stuart News. “I lost the bees, the ability to make honey and the ability to sell the bees.”—Smith told Florida Today that he lost $150,000 from the incident.–State officials are testing the bees to determine what type of chemicals contributed to their deaths.–Experts say pesticides might be behind the lost beehives.—“The fact that it was so widespread and so rapid, I think you can pretty much rule out disease,” Bill Kern, an entomologist with the University of Florida’s Research and Education Center, told Florida Today. “It happened essentially almost in one day. Usually diseases affect adults or the brood, you don’t have something that kills them both.”—The case in Micco, 18 miles south of Melbourne, is being investigated by state agriculture officials and the sheriff’s office.

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    12 milion bees found dead in Florida and no one knows why!

    Authorities have already ruled out disease, including the infamous “Colony Collapse Disorder” (CCD), as the cause of a recent honeybee holocaust that took place in Brevard County, Florida. The UK’s Daily Mail reports that up to 12 million bees from roughly 800 apiaries in the area all dropped dead at roughly the same time around September 26 — and local beekeepers say pesticides are likely to blame. CCD is the term often used to describe the inexplicable mass die-off of honeybees around the world, which typically involves honeybees leaving their hives and, for whatever reason, never finding their way back home[U1]. Mass die-offs associated with CCD often occur at seemingly random locations around the world, and typically involve a gradual process of disappearance and eventual colony collapse — and the dead bees are typically nowhere to be found. But the recent Florida event involved hundreds of colonies from 30 different sites in a one-and-a-half mile radius literally dropping dead all at the same time and leaving their carcasses behind, which is why authorities have dismissed CCD as the cause. Based on the appearance of the dead bees, as well as the synchronous timing of their deaths, pesticide sprayings appear to be the culprit in this case. “I’m a pretty tough guy, but it is heart wrenching,” said Charles Smith of Smith Family Honey Company to News 13 in Orlando. His family’s company lost an estimated $150,000 worth of bees in the recent die-off. “Not only is it a monetary loss here, but we work really hard on these bees to keep them in good health.” The Florida die-off coincides with a recent county-wide mosquito eradication effort, during which helicopters flew over various parts of the county and sprayed airborne pesticides. Officials, of course, deny that this taxpayer-funded spraying initiative had anything to do with the bee genocide, though. “The fact that it was so widespread and so rapid, I think you can pretty much rule out disease,” said Bill Kern, an entomologist from the University of Florida (UF) toFlorida Today. “It happened essentially almost in one day. Usually diseases affect adults or the brood, you don’t have something that kills them both.”[U2] Many of the beekeepers who lost their hives in the mass killing raised their bees to sell to American farmers, who then used them to pollinate food crops. Because of their massive losses, many of these beekeepers could end up losing their entire beekeeping businesses.

    http://majortrend.tv/611/up-to-12-million-bees-found-dead-in-florida-and-no-one-knows-why/

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    Higher Risk of Birth Defects from Assisted Reproduction

    A University of Adelaide study has identified the risk of major birth defects associated with different types of assisted reproductive technology. —ScienceDaily (May 5, 2012) — A University of Adelaide study has identified the risk of major birth defects associated with different types of assisted reproductive technology.—In the most comprehensive study of its kind in the world, researchers from the University’s Robinson Institute have compared the risk of major birth defects for each of the reproductive therapies commonly available internationally, such as: IVF (in vitro fertilization), ICSI (intracytoplasmic sperm injection) and ovulation induction. They also compared the risk of birth defects after fresh and frozen embryo transfer.–The results are being published May 5 in the New England Journal of Medicine, and presented in Barcelona, Spain at the World Congress on Building Consensus in Gynecology, Infertility and Perinatology.–“While assisted reproductive technologies are associated with an increased risk of major birth defects overall, we found significant differences in risk between available treatments,” says the lead author of the study, Associate Professor Michael Davies from the University of Adelaide’s Robinson Institute and School of Paediatrics and Reproductive Health.–Researchers linked a census of more than 6100 assisted reproductive technology births in South Australia to a registry of more than 300,000 births and 18,000 birth defects. They compared risks of birth defects across all infertility treatments to pregnancies in women with no record of infertility. They also compared successive pregnancies for women.–Previous studies have identified an increased risk of birth defects associated with infertility treatment, but this is the first study to compare all forms of available treatment. This is also the first study to compare pregnancies within women by the treatments received.–“The unadjusted risk of any birth defect in pregnancies involving assisted conception was 8.3% (513 defects), compared with 5.8% for pregnancies not involving assisted conception (17,546 defects),” Associate Professor Davies says.–“The risk of birth defects for IVF was 7.2% (165 birth defects); and the rate for ICSI was higher at 9.9% (139 defects).-“A history of infertility, either with or without assisted conception, was also significantly associated with birth defects. While factors associated with the causes of infertility explained the excess risk associated with IVF, the increased risk for a number of other treatments could not readily be explained by patient factors. ICSI, for instance, had a 57% increase in the odds of major defect, although the absolute size of the risk remained relatively small,” he says.—Associate Professor Davies says cryopreservation (freezing) of embryos was associated with a substantially reduced risk of birth defects, particularly for ICSI. “This may be due to developmentally compromised embryos failing to survive the freeze/thaw process,” he says.——Also of concern was the tripling of risk in women using clomiphene citrate to stimulate ovulation outside of a closely supervised clinical setting.—“While confined to a small group in our study, this is of particular concern as clomiphene citrate is now very widely available at low cost, and may easily be used contrary to manufacturers’ very specific instructions to avoid use if pregnant, as it may cause fetal malformations. This aspect of the study will need additional confirmation from future research,” Associate Professor Davies says.—He says the study now needs to be expanded to include more recent years of treatment, as the reproductive technologies have undergone continual innovation which may influence the associated risks of treatment.

    Background———World wide, more than 3.7 million babies are born annually as a result of assisted reproductive technology.—Assisted reproduction is usually invasive, expensive, and deals with matters of intense emotional content.—There are several areas of public health interest.

    These include:

    Risks associated with multiple embryo transfer
    Risks to the health of the offspring as a result of treatment
    Patient mental health as a result of treatment
    Long-term social functioning of the offspring born as a result of assisted reproduction.
    Story Source-The above story is reprinted from materials provided by University of Adelaide, via Newswise. —Journal Reference-Michael J. Davies, Vivienne M. Moore, Kristyn J. Willson, B.Sc., Phillipa Van Essen, Kevin Priest, Heather Scott, Eric A. Haan, Annabelle Chan. Reproductive Technologies and the Risk of Birth Defects. New England Journal of Medicine, 2012; : 120505030011004 DOI: 10.1056/NEJMoa1008095

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    Strengthening Foods For Fevers or in Weakness

     

    Beef Tea-the Method to make this requires a soaking of beef in cold water ( 1 pint- 473 mil ) for 2 hours and to be heated for 3 hours at a mid range heat ( 160 fahr- 71 cel ) as the water being lost add cups pf cold water to sustain the levels-after the time frame , strain the beef thoroughly, and utilize 3 oz

     

    Sheep Broth –add one pound-defatted and deboned—allow to soak in (3 pints – 1.41 litre )of water then heat mid range as with the beef—adding salt and onion to it for flavouring and preserving-for several hours—add water when needed to sustain the levels-strain the lamb-pour into a bowl and allow to cool . strain off excess fat can be heated and utilized

     

    Chicken Broth – Skin the chicken and clean and chop in small pieces then boil it bone and all for an hour adding mace( nutmeg) and parsely in a quart of water ( 32 0z or 1 litre 33 oz ) strain afterwards—

     

    To make these more absorbable add either hcl ( hydrochloric acid ) Lactic Acid or pepsin—either take as a supplement with the solution or add it to the mix in small amounts to increase the uptake

     

    Beef Essence-Pound Meat into a Mortar till the essence comes out –Another way is to extract it in a jar with the lid on loosely and allow a double broiling effect—by puncturing the meat with the fork and then placing meat in the jar and placing a jar in a pot of water and allow the water to be heated from mid range to boiling and allow this to go on for 1 hour—either method to extract the meat juices will be sufficient—-once this is extracted then mix with either brandy-vodka or wine or spirits –

     

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    Menthol Suppresses Nicotinic Acetylcholine Receptor Functioning in Sensory Neurons via Allosteric Modulation.

    Hans M, Wilhelm M, Swandulla D.

    Source—Department of Physiology, University of Bonn, Nussallee 11, D-53115 Bonn, Germany.

    Abstract

    In this study, we have investigated how the function of native and recombinant nicotinic acetylcholine receptors (nAChRs) is modulated by the monoterpenoid alcohol from peppermint (-) menthol. In trigeminal neurons (TG), we found that nicotine (75 μM)-activated whole-cell currents through nAChRs were reversibly reduced by menthol in a concentration-dependent manner with an IC(50) of 111 μM. To analyze the mechanism underlying menthol’s action in more detail, we used single channel and whole-cell recordings from recombinant human α4β2 nAChR expressed in HEK tsA201 cells. Here, we found a shortening of channel open time and a prolongation of channel closed time, and an increase in single channel amplitude leading in summary to a reduction in single channel current. Furthermore, menthol did not affect nicotine’s EC(50) value for currents through recombinant human α4β2 nAChRs but caused a significant reduction in nicotine’s efficacy. Taken together, these findings indicate that menthol is a negative allosteric modulator of nAChRs

     

    TOP A

    [U1]Frequencies and the magnetic field disruption—or even a THz signal may be the cause of this
    [U2]Unless it is Genetically Modified or enhamced to by pass the normal safety Parameters—-

     

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    TOP B

    HOME

     

    Show of the Week May 11-2012

     

    Benefits of Red Meat

     

    Dr Oz belly blasting segment prompts sales ‘explosion’ for 7-Keto

     

    A farmer is criminally charged for providing fresh food to mothers.

     

    Garden Savory

     

    Experimental study on Satureja montana as a treatment for premature ejaculation– Recipe

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    Benefits of Red Meat

    It was reporting on the latest meat-eating health scare, which was generated by a paper published in the US Archives of Internal Medicine.—US meat is not grass fed –as the European meat is

    The article continued in a similar vein about how if you ate more than a certain amount of red meat you’d die early but if you ate different sources of protein instead you wouldn’t. It begs the question: How you would know if you’d died earlier than you might otherwise have done? It even said: “Nuts were said to reduce the risk of dying by 20%.” Surely that did not intend to imply that some people who ate nuts would not die at all?—The Times’ journalist’s suggestion that roast beef should be swapped for nut roast may not be such a great idea for those wishing to control their calorie intake when lean beef has fewer calories than nut roast.

    Healthy combination–Moreover, only about 50% of the fat in beef is saturated and half of that is stearic acid, which is rapidly converted in the body to oleic acid, which is a monounsaturated fat. That, together with another fatty acid constituent of beef fat, palmitic acid, is believed to lower LDL (bad) cholesterol. The rest of the fat in beef fat is monounsaturated and polyunsaturated. So, altogether, we have a rather healthy combination. It is a similar story for lamb fat.—All meat lovers should rejoice, particularly if they are eating grass-fed beef or lamb. Apart from having the healthiest fat composition, they also contain healthy proportions of omega-3 to omega-6 fatty acids.[U1] Most British beef and lamb are grass-fed but in the US where the paper referred to at the beginning of this article was written most animals are not grass fed.

    Heart disease—-Research at Ohio State University has reported that people whose diets contain too much omega-6 are more susceptible to a range of degenerative diseases, including heart disease. Polyunsaturated fats in vegetable oils contain high levels of omega-6 so, if the Ohio research stands, replacing animal with vegetable fats in the diet is not necessarily the best option.—The information on that composition is contained in Jennifer McLagan’s book: Fat, an appreciation of a misunderstood ingredient. I always turn to it for advice to balance the anti-meat stories, particularly those relating to diet and health.—The chemical composition of fat in meat is a matter of fact from which you can form your own opinion when people tell you that fat in meat is unhealthy compared with vegetable oil.

     

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    Dr Oz belly blasting segment prompts sales ‘explosion’ for 7-Keto

    Sales of 7-Keto have exploded following a mention on the Dr Oz show in February, with brand owner Humanetics Corp “on track to post triple digit gains this year” for the fat-burning ingredient, should current sales trends continue.—While 7-Keto has been growing steadily since its launch in 1998 – Humanetics has struck licensing deals with more than 100 firms that now use it in dietary supplements – sales have “caught fire” since it featured in a ‘belly blasting’ segment on Dr Oz, said NutraBridge president Scott Steil.—There are still snake oil merchants out there—-Steil, who promotes 7-Keto on behalf of Humanetics, said Dr Oz had introduced 7-Keto to a new wave of consumers as well as reminding those already familiar with it that it is one of the few weight management ingredients supported by strong human clinical data in a market that has been plagued by its fair share of snake oil merchants.[U2]–He added: “There are still snake oil merchants out there. But we’ve seen a few of them hit pretty badly recently and people are beginning to realize that if you want to play in this market, you’ve got to do it right.[U3]—“I’d say the weight management category is probably the most dynamic it’s been for four or five years, but what’s interesting is that it’s not the latest and greatest thing that’s driving it at the moment, but more established products.—“We’ve seen the FDA and the FTC crack down on companies making unsubstantiated claims as well as several class action lawsuits. But I think Dr Oz has also helped raise awareness about legitimate weight loss ingredients[U4]. He talks a lot about weight management and he doesn’t recommend products that are in what I’d call the borderline or the greyzone.”—NDI guidance and weight loss ingredients—Similarly, the current debate over the NDI draft guidance was focusing minds on which ingredients have gone through the necessary regulatory approvals to be used in dietary supplements, said Steil.–He added: “There are probably more than 40 ingredients that fall into the weight loss category and many of them that should have gone through the NDI (new dietary ingredient) notification process, have not done so.”Humanetics submitted two NDI notifications for 7-Keto in 1997 and 2002 received no objections from the FDA.[U5] –[U6]However, speaking at a public hearing about the NDI process in November 2004, its chief medical and scientific officer Dr John Zenk said he and others in the room could all think of several ingredients that “would be considered new dietary ingredients for which no pre-market notification has been filed”.—What is 7-Keto?–A metabolite of DHEA that is found naturally in the body and “declines dramatically as we age”, says Steil, “7-Keto increases the activity of fat-burning enzymes and increases metabolism without the use of stimulants.–“By the time you reach 40, you’ve lost 50% of your normal 7-Keto levels and by 60 you’ve lost 70-75%, so you can benefit from taking 7-Keto from around your 30s onwards,” he claimed.—“But we also know that anyone that goes on a calorie-restricted diet will also benefit as your body responds to calorie restriction by slowing down your metabolism.[U7] Taking 7-Keto effectively eliminates this effect so your diet can be totally effective.”—Humanetics has filed a suite of patents around 7-Keto since the early 1990s in areas including immune modulation and weight management, and has also invested a significant sum in human clinical data to support its claimed effects, said Steil.—“We’ve got 11 human clinical studies looking at 7-Keto alone or in combination with other ingredients. They have repeatedly shown that people on diet and exercise programs taking 7-Keto lose three times more weight than those on the same program taking a placebo.”[U8]

    Beyond weight management?

    Right now, Humanetics has its “hands full with weight management”, said Steil. However, it is also exploring some other indications for 7-Keto.—“When it comes to weight loss, we have proved its efficacy again and again, but looking at the mechanism of action beyond its effect on fat burning enzymes could open up some new areas of opportunity. How does it affect neurotransmitters in the brain, for example?”

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    Mothers are threatened with criminal charges, but will continue openly defying MDA; and a farmer is criminally charged for providing fresh food to mothers.

    —Several Minnesota moms who facilitate access to local farm food are planning to act despite the risk of criminal charges laid out in warnings from the Minnesota Department of Agriculture (MDA).–The MDA has threatened several of them, and has already conducted investigations against them. The letters warn that if they continue helping provide fresh food to their friends and neighbors, the MDA will press criminal charges and prosecute. The MDA holds that the mothers are violating food-handling regulations.[U9]–Here, Melinda Olsen discusses the ordeal in detail – she only helps the farmer for free by storing goods in her garage for others. No commerce. Yet, she is ominously threatened by MDA for food crimes. —-Dozens in the Minneapolis area are disgusted at the MDA’s overly aggressive tactics and are expected to join in the civil disobedience as their natural right to food access. Hundreds of supporters are expected at the rally, below.-Melinda Olson is a mom who received one such MDA warning letter, and said–It is absolutely outrageous that during this time of economic crisis our state government is investigating and sending warning letters to mothers and putting farmers on trial who are helping provide communities with fresh foods. It is my right to contract privately with a farmer for the food of my choice just as it is the right of every American. —The MDA’s harassment against mothers will not work. We plan to ignore this warning and continue operating as we are.[U10] MDA should not waste taxpayer money investigating, prosecuting and jailing peaceful farmers and mothers for helping their communities secure fresh foods. Our time to stand up against this tyranny is now!—Additionally, the MDA has brought charges against two local farmers for supplying their communities with fresh foods. Mothers who rely on the food and delivery service of one of these farmers, Alvin Schlangen, are facing loss of their food supply if Schlangen ends up jailed as warned by MDA. Among his four misdemeanor charges for providing the food? Handling food without a permit-Mislabeling food-Handling unprocessed, fresh milk; a crime, according to the MDA—You can read more about their plight – here—Minnesota Food Freedom Rally Detail—Customers and supporters from around the state and country have planned a rally for Schlangen on the first day of his criminal trial on Monday, May 14 at 7:00 a.m. outside the Minneapolis courthouse. Supporters will sign a “Declaration of Food Independence” and demonstrate non-compliance against what they deem “unjust” regulations. The Rally is followed by a peaceful sit-in of Alvin’s trial at 9:00 a.m., Hennepin County Government Center 300 S. 6th Street, Minneapolis, MN, 55487. An important workshop will take place on May 13th. More event details including “Know Your Rights” Mother’s day workshop and speakers, can be found at Raw Milk Freedom Riders.

    This is a Test – The Time to Nip The War on Fresh Food Access is Now!

    The show host in the first video makes the point that if these agencies are to be consistent, then it would mean shutting down church drives and other outreaches. And that’s just what will happen if we allow these attacks – it is happening. We’re not even allowed to feed a hungry person for free – and it’s all about power over, not a sincere attempt at public safety. These actions are not based on legitimate complaints, but blind adherence to regulation, created for the purpose of force and not tempered with any empathy.—If we allow these power hungry brutes to run over moms and small farmers now, any shred of hope for our basic food rights will be snatched from our plates for good. Do we want to be called criminals and become imprisoned for giving our neighbors some bread?-Just like the Amish men who said “We’re just not going to pay,” the key to a real power shift appears to be non-acquiescence. Just as in their case; it is bad, arbitrary laws, edicts, and mandates that must change when enough people say “Enough!” We do not acknowledge their puffed up authority in matters of our natural right to the foods we choose.

    Press Release-http://rawmilkfreedomriders.wordpress.com/press/mothers-threatened-with-criminal-charges-openly-defy-mda/

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    – Garden Savory

    [Saturin – effective vegetative remedy in treatment of type 2 diabetes mellitus].

    [Article in Russian]—Kemertelidze E, Sagareishvili T, Syrov V, Khushbaktova Z, Tsutskiridze L, Kurashvili R.

    Source–Tbilisi State Medical University, I. Kutateladze Institute of Pharmacochemistry, Georgia.

    Abstract

    A chemical investigation of plant Satureja hortensis L. – garden savory (GS) has been carried out. It is established that the GS is rich in phenolic compounds. Flavonoids apigenin, luteolin, cinaroside, luteolin-glucuronide, luteolin-rutinoside[U11], isoroifolin and phenylcarbonic acids – chlorogenic acid and rosmarinic acid were isolated from the leaves of the plant. The total content of flavonoids and phenylcarbonic acids in GS is 1,6-1,7%. The leaves of GS contain up to 1% essential oil consisting mainly of thymol and methyl carvacrol. Dry aqueous extract of GS leaves, which retains the full range of substances of raw plant material has been obtained. Pharmacological investigation of the GS extract was carried out on intact animals and animals with experimental alloxan diabetes. Antidiabetic Arfasetine was chosen as a reference drug. The study revealed that the GS extract exhibits hypoglycemic activity significantly reducing blood sugar levels and is safe in the long run. Drug dosage form named saturin – capsules containing 0,33 g [U12]of dried aqueous extract of GS leaves, has been developed. Clinical trials of Saturin confirmed its effiacy in diabetes mellitus type 2. The drug is registered by the Ministry of Health, Labour and Social Welfare of Georgia (Registration Certificate №003658) and approved for use in type 2 diabetes either independently or in combination with other hypoglycemic agents. Saturin is manufactured at the Experimental and Production Facility of the Institute of Pharmacochemistry.

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    Experimental study on Satureja montana as a treatment for premature ejaculation.
    Zavatti M, Zanoli P, Benelli A, Rivasi M, Baraldi C, Baraldi M.

    Source-Department of Anatomy and Histology, University of Modena and Reggio Emilia, Via del Pozzo 71, 41100 Modena, Italy. manuela.zavatti@unimore.it
    Abstract—AIM OF THE STUDY–Satureja montana (winter savory) is a medicinal plant traditionally used to treat different disorders including male sexual dysfunction. In this study we evaluated the effect of Satureja montana hydroalcoholic extract on copulatory behavior of sexually potent male rats.
    MATERIALS AND METHODS:
    The extract was orally administered acutely or repetitively for 8 consecutive days at the doses of 25 and 50 mg/kg. The main parameters of sexual behavior, mount (ML), intromission (IL), ejaculation (EL) latencies and post-ejaculatory interval (PEI), were evaluated in animals submitted to mating test and multiple ejaculations test. Testosterone serum levels were measured in rats acutely treated with Satureja montana extract dosed at 50 mg/kg[U13]. In addition the open field test was conducted to evaluate the locomotor behavior.

    RESULTS:
    When acutely administered at both dosages, the extract was able to significantly increase EL and decrease intromission frequency (IF) in comparison with controls. The significant increase in EL was found also when the extract was subacutely administered, daily for 8 consecutive days, at the dose of 25 mg/kg. In the multiple ejaculations test, EL values of treated rats were significantly increased during the 1st and 2nd sequence in comparison with controls; in addition only rats treated with the extract were able to reach the 4th ejaculation within 30 min. Testosterone serum level measured in rats acutely treated with Satureja montana at the dose of 50 mg/kg was significantly increased in rats in comparison with controls. Finally, the locomotor activity recorded in the open field test was not affected by the acute administration of the plant extract.

    CONCLUSIONS:
    These data suggest that Satureja montana could be considered as a natural remedy for the treatment of premature ejaculation delaying ejaculation latency without exerting any negative effect on the other parameters of sexual behavior and without exerting a sedative effect. In addition the increased serum level of testosterone confirms the positive influence of Satureja montana on male sexual function.

    Recipe —the simplest way to do this would be to make a extract/tincture—by using the jar blender method—using a blender end or bottom –add your herb ( savoury ) inside and seal the jar with the blade attachment- then once pulverized then add your clean and or clear alcohol an blend it for about 10 Min+ and then strain half and put into 2 separate jars—the one you will add to a pot to boil down about half the other keep just in case there is an error—when done strain then add to pot and allow to boil add water about a tablespoon and when it gets down to a point of half stop stove—take the content of the pot add to a glass jar—add on top of the metal that will diffuse—–this will further extract out the water and will get a super concentrate and will need at this point 1-2 drops

    #352
    Avatarwebmaster
    Keymaster

    [U1]Grass fed animals for meat consumption have 13 times more omega 3 then fish without the mercury and other harmful contaminats fish come in contact with that cows or sheep do not—even chickens or poultry on a grass fed type eating and not the factory fed have a higher content of omega 3 in them then today;’s fish
    [U2]This is like the pot calling the kettle black—this works —hit and miss at best—the interesting thing about scientific research and data is all in how it is done to convey a message in favour of your interest—this has not worked, for most people and the reason why can be attributed to a lot of things—why it sold is due to the fact that a major TV player advertised this and there is a easy moniker of monkey see and monkey do—mob mentality would do this
    [U3]WOW in other words if you have something that works they will attack it or yank it—if it is useless and see’s so little results the this will be allowed !
    [U4]What Dr Oz has done is lined his pockets with monies that he should not have gotten and the promotional pay out must make him a commodity

    [U5]Why would they?? The stuff doesn’t work or has minimal results on a human being—it may offer some benefits to an animal that may not produce this particular metabolite and so it would work—but on the rest of us that do produce thi—nothing is going to happen
    [U6]Again why would they—it’s ineffective
    [U7]No we are getting to the truth—Calorie restriction—Now we are seeing why it works —has nothing to do with the supplement—it has to do with the simple equation take in less and expound what you normally do and will see a flattening of the belly
    [U8]Now we are making claims that cannot be substantiated
    [U9]What A crock of BS eh!!! What they are doing is setting the stage for a revolution—and if the farmers were smart they would band together here and use this as a means to break away from the yolk these MDA and the Agra Globalist has put on them—this frightens the establishment—Autonomy—and it frightens the banks even more—loose money they cannot control
    [U10]Now That’s what I call Testosterone
    [U11]These are as well Estrogen removers and regulators –something males in general and women with high levels of estrogen may want to consider in the usage in there daily eating habits or in a tea as well

    [U12]330 mgs

    [U13]take your body weight—divide by 2.2 an then divide the 50mgs into the kg—175 lb=79.9 kgs/50 mgs and you get-1.598 0r almost 1.6 grams per 79 kilo

    #353
    Avatarwebmaster
    Keymaster

    Increasing Predator-Friendly Land Can Help Farmers Reduce Costs

     

    Having large tracts of natural habitat surrounding fields increase ladybug populations and help farmers reduce insecticide use—-ScienceDaily (May 11, 2012) — Having natural habitat in farming areas that supports ladybugs could help increase their abundance in crops where they control pests and help farmers reduce their costs, says a Michigan State University study.—Ladybugs and other predatory insects eat crop pests, saving farmers an estimated $4.6 billion a year on insecticides. Non-crop plants provide these predatory insects with food and shelter, helping them to survive and thrive in areas where they are needed. In an attempt to increase benefits from predatory insects, researchers have often planted strips of flowers along the edges of crop fields[U1]. –However, natural habitats also provide vital food and shelter resources and may be more important for pest control, said Megan Woltz, MSU doctoral student and co-author of the study that appears in the current issue of Agriculture, Ecosystems and Environment.–“Creating predator-attracting habitats next to crops is only a partial solution,” said Woltz, who co-authored the study with MSU entomologists Doug Landis and Rufus Isaacs. “Ladybugs and many other pest-eating insects travel long distances throughout the growing season, sometimes flying or crawling over many miles as they search for food and shelter. So we also have to consider what resources are available to these predators at larger scales.”–Ladybugs are heralded as a natural, effective killer of soybean aphids, the most-destructive soybean pest in the northern United States. To determine the best way to attract ladybugs to soybean fields, researchers planted buckwheat strips next to soybean fields and also examined the amount of natural habitat within 1.5 miles of the fields.—“Ladybugs loved our buckwheat strips,” Woltz said. “We always found way more ladybugs in the buckwheat than are usually in field edges. Unfortunately, all of the ladybugs in the buckwheat did little to change their populations in the soybean fields.”—Ultimately, natural habitat proved to be more important. The amount of grasslands and forests within 1.5 miles of the soybean fields determined how many ladybugs ended up in the field, she added.—Such large areas typically encompass multiple farms, suggesting that rural neighbors may need to work together. In other studies, landscapes with at least 20 percent of non-crop habitat showed good pest control. Providing some habitat on every farm and the properties that surround them would add up to a lot of habitat at the landscape scale — the scale that matters to ladybugs.—Story Source-The above story is reprinted from materials provided by Michigan State University. –Journal Reference-J. Megan Woltz, Rufus Isaacs, Douglas A. Landis. Landscape structure and habitat management differentially influence insect natural enemies in an agricultural landscape. Agriculture, Ecosystems & Environment, 2012; 152: 40 DOI: 10.1016/j.agee.2012.02.008

     

    Sustainable Agriculture: Perennial Plants Produce More; Landscape Diversity Creates Habitat For Pest Enemies

     

    ScienceDaily (Aug. 4, 2009) — Advances in ecology increasingly reveal that conventional agricultural practices have detrimental effects on the landscape ecology, creating problems for long-term sustainability of crops. In a series of sessions at the Ecological Society of America’s Annual Meeting, ecologists will present their ideas on how our agricultural practices can take lessons from natural environments.

    Perennial plants produce more, require less input than annual croplands—–The major crops used globally to feed people and livestock – wheat, rice, maize and soy – are based on an annual system, in which crop plants live one year, are harvested, and are replanted the following year. These systems are notorious, however, for stripping organic nutrients from soils over time.—Perennial systems, on the other hand, contain plants that live longer than one year despite being harvested annually. Many agricultural scientists, including Jerry Glover of The Land Institute, say that perennial crops are the key to creating more sustainable agricultural systems.—“Across agricultural history, we’ve fundamentally relied on annual grain crops,” Glover says. “But at the same time we rely on them, they’re degrading the ecosystems they’re in, which reduces their productivity.”—To compare the long-term sustainability of these two cropping systems, Glover and his colleagues conducted a study on the physical, biological and chemical differences between annual wheat fields and perennial grass fields in Kansas. The fields had each been harvested annually for the past 75 years.—In each test, the researchers found perennial fields to be healthier and more sustainable ecosystems. In the perennial fields, the plants’ total root mass was more than seven times that of the annuals, and the roots infiltrated about a foot deeper into the ground. The perennial fields also had higher soil microbe biodiversity and higher levels of dissolved carbon and nitrogen in the soil. All these findings, says Glover, suggest that the perennial field soil is healthy enough to maintain high levels of organic nutrients.—–In addition to being more ecologically sustainable, Glover’s team found that the perennial fields were more energy-efficient in providing productive harvests. Although only the annual fields received yearly fertilizer inputs, the perennial fields yielded 23 percent more nitrogen harvested over the 75 years, despite requiring only 8 percent of the energy inputs in the field – such as fertilizer and harvesting operations – as the annual systems.–Glover says that these results clearly show the need to move away from annual crops and increase our use and domestication of perennial crops.—-“So far, little effort has been made to improve perennial crops,” he says. “Some of greatest possibilities for transforming agriculture may well come from overlooked systems such as perennial grasses.”

    Landscape diversity creates habitat for pest enemies—Farmers spend millions of dollars each year on pesticides to kill crop-eating insects. But these insects have natural enemies, too, and new research is investigating what farmers can do to encourage the proliferation of these pest-eaters. One study, presented as a talk at the ESA meeting, shows that increasing the natural habitat in and around farms can boost populations of pests’ natural enemies.—Rebecca Chaplin-Kramer of the University of California Berkeley surveyed the abundance of flies, ladybugs, wasps and other predators of a common agricultural pest, the cabbage aphid, in croplands ranging from 2 percent to about 80 percent natural vegetation. She found that as the proportion of natural area – or complexity – increased, so did the numbers of natural enemies in the croplands.—Chaplin-Kramer shows that increases in predators didn’t always result in fewer aphids in the croplands, but she points out that agents of control are only half of the equation and sources of the pests themselves must also be considered. In the absence of predators, pest levels would likely rise even more dramatically.—“By having complexity, you’re supplying a community of insects to that farm that will be waiting when –and if – more pests show up,” Chaplin-Kramer says.–Fostering larger predator communities is time-consuming and can take years to show results, Chaplin-Kramer says, which is why many farmers are skeptical of the idea. But, she says, there’s no doubt that a strong predator base is more sustainable than simply using pesticides.—“Pesticides are a short-term solution, because pests can build up resistance, and new pesticides are constantly being developed,” she says. “Building up predator communities takes time, but the systems are more stable and will provide more ecosystem services in the long term.”

    Reduced tilling improves soil microbe biodiversity—The idea of using biological instead of chemical methods to create healthy croplands doesn’t include just above-ground approaches. Soil bacteria can affect the growth and success of crop plants by fixing nitrogen, aiding in the uptake of nutrients and decomposing dead organic matter. Some current farming practices, however, may disrupt the soil ecosystem and decrease the effectiveness of the microbe community.—In his poster, Shashi Kumar of Texas Tech University will explore the relationship between conventional tilling and low-tilling practices on farms in semi-arid areas of west Texas. In areas where soil tilling was kept at a minimum, Kumar and his colleagues found a higher diversity of soil bacteria; conventional tilling produced lower bacterial diversity.—Kumar says that conventional tillage systems disrupt soil particles and decrease soil pore size, which can lead to decreased water and soil access for microbes. Although he recognizes that tillage is necessary, he thinks that farmers can reduce their tillage, even in semi-arid regions, to promote soil bacterial biodiversity.—-“We are currently using so many different crop management systems, like pesticides, insecticides and fungicides, which are damaging to our soil system,” Kumar says. “Why shouldn’t we focus on biological methods, since the bacteria are already there?”—Story Source-The above story is reprinted from materials provided by Ecological Society of America, via EurekAlert!, a service of AAAS.

     

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    Diversifying Crops May Protect Yields Against a More Variable Climate

    ScienceDaily (Mar. 1, 2011) — A survey of how farmers could protect themselves by growing a greater diversity of crops, published in the March issue of BioScience, has highlighted economical steps that farmers could take to minimize the threat to crops from global climate change, including a greater frequency of extreme climate events.–Adaptation to ongoing climate change is considered a policy priority for agriculture. The survey, by Brenda B. Lin of the Australian Commonwealth Scientific and Industrial Research Organization, documents multiple instances of farmers protecting economically important crops, such as rice and other cereals, alfalfa, and coffee, from outbreaks of pests and disease, often associated with climate change, or simply from changed physical conditions. s.—Such techniques The farmers succeeded by switching from growing a single variety of crop to growing a broader range of species or varieties, either at the same time or in rotation, or by introducing structural variety into uniform fieldwork, in general, because they make it harder for pathogens and pests to spread, and they may modulate climate extremes the crops experience. Not all attempts at agricultural diversification lead to such benefits, Lin points out.—Yet increasingly, farmers have access to crop modeling techniques that can evaluate when a given adaptation technique might provide an economic benefit. Because accurate modeling requires extensive knowledge of on-the-ground data, such as soil profiles for water and nutrients, Lin argues for the development of extension and research staff who can assist farmers in gaining the information they need to use modeling techniques for adaptation.– Story Source–The above story is reprinted from materials provided by American Institute of Biological Sciences, via EurekAlert!, a service of AAAS. —Journal Reference-Brenda B. Lin. Resilience in Agriculture through Crop Diversification: Adaptive Management for Environmental Change. BioScience, March 2011

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    Cancer-Fighting Goodness Found in Cholesterol, Study Suggests

    ScienceDaily (Apr. 19, 2012) — A Simon Fraser University researcher is among four scientists who argue that cholesterol may slow or stop cancer cell growth. They describe how cholesterol-binding proteins called ORPs may control cell growth in A Detour for Yeast Oxysterol Binding Proteins, a paper published in the latest issue of the Journal of Biological Chemistry.—The scientists came to their conclusion while trying to understand how cholesterol moves around inside cells in the fat’s journey to cell surfaces where it reinforces their outer membrane.[U2]—“The assumption was that ORPs bind and transport cholesterol inside cells in a similar fashion to how lipoproteins bind and move around the fat outside cells through the blood stream,” explains Chris Beh. The SFU associate professor of molecular biology and biochemistry co-authored this paper.—Beh and his colleagues noted that genetic changes engineered by them block the ability of ORPs to bind cholesterol but don’t stop ORPs from functioning. In fact, these altered ORPs work better and activate other regulator proteins, which in turn trigger a variety of cellular processes that stimulate cell growth.—The scientists believe this happened because cholesterol-binding normally interferes with ORPs’ ability to bind to another lipid or fat called PI4P, which is important for cell growth.—“That told us that ORPs probably have nothing to do with moving around cholesterol within cells,” says Beh. “Rather cholesterol-binding puts the brakes on ORP’s ability to bind to PI4P which, if left unchecked, could accelerate cell growth like crazy,” says Beh. “Given that uncontrolled cell growth is a key feature of cancer, this means gaining a better understanding of the true purpose of cholesterol-binding within cells could be important in cancer treatment.”—Beh and his colleagues draw on two important facts to support their conclusion.-“First, cancer cells require ORPs to survive,” explains Beh. “Second, other scientists have previously shown that a new class of natural compounds that look like steroids or cholesterol can kill a broad spectrum of different cancer cells.”—Beh says he and his research partners will now find out exactly which proteins respond to ORP activation and under what circumstances does cholesterol turn off ORP’s activation of them.—Story Source-The above story is reprinted from materials provided by Simon Fraser University. –Journal Reference-C. T. Beh, C. R. McMaster, K. G. Kozminski, A. K. Menon. A Detour for Yeast Oxysterol Binding Proteins. Journal of Biological Chemistry, 2012; 287 (14): 11481 DOI: 10.1074/jbc.R111.338400

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    Benefits and Uses of Cholesterol—

     

    Serum Cholesterol levels below 160 mg/dL are considered sub-optimal (persons with sub-optimal Cholesterol levels have a greater incidence of Stroke, Lung Ailments, some types of Cancer and Alcoholism).— The majority of the body’s Cholesterol is concentrated in Cell Membranes.— Optimal serum Cholesterol levels help to prevent some types of Cerebrovascular Diseases and sub-optimal Cholesterol levels have been associated with an increased risk of Cerebrovascular Diseases—- Low Cholesterol levels may increase the risk of Cancer.— Cholesterol possesses Antioxidant properties– Optimal levels of Cholesterol are required in order to prevent Depression — Cholesterol (after its secretion by glands in the Skin) protects the Skin against infection by Detrimental Bacteria and Detrimental Fungi.—-

    How to Get Cholesterol—you can either buy it as a supplement form as coconut oil—ghee-butter—palm oil— or cream –can be bought in capsule or container —or go to the local farm and buy direct—

     

     

    TOP C

    [U1]Planting Flowers is another natural way to rid the garden of pest
    [U2]This is Required for cellular connection as well as processes and integrity of our cellular structure

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    Show of the Week May 18-2012

     

    DNA-Destroying Chip Being Embedded Into Mobile Phones

     

    Oral supplementation of turmeric decreases proteinuria, hematuria, and systolic blood pressure

     

    Antioxidant-rich watercress shows sports nutrition potential

     

    The ability of an ethanol extract of Cinnamomum cassia to inhibit inflammatory action

     

    Plant Diversity Is Key to Maintaining Productive Vegetation

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    http://www.fourwinds10.net/siterun_data/health/harmful_products/news.php?q=1336238898

     

    DNA-Destroying Chip Being Embedded Into Mobile Phones

    According to Dr. Boian Alexandrov at the Center for Nonlinear Studies at Los Alamos National Laboratory in New Mexico, terahertz (THz) waves destroy human DNA. The waves literally unzip the helix strand. Now a team of technologists at UT Dallas are planning to take chips broadcasting THz waves and embed them into mobile phones for use as an imaging system for consumers, law enforcement and medical personnel… a potentially deadly technology that could eventually kill or sicken millions of people.—The controversial THz scanner technology used by the TSA at many of the nation’s airports is being adapted for cell phone use. Studies of terahertz radiation have caused experts to raise alarms over the significant health risks to humans.—-Recently major media touted a new chip that permits the adaption of a THz generating device to be embedded into cellular phones.—-Is the price for seeing through walls, a grisly death?—The excited press painted grand pictures of such technology being used by consumers to see through walls and objects, while health professionals like physcians might incorporate the technology to seek out small tumors inside patients without the need for invasive surgery.—The THz wave—located between microwaves and infrared on the electromagnetic spectrum—was chosen for security devices because it penetrates matter such as clothing, wood, paper and other porous material that’s non-conducting. At the time experts believed this type of radiation was harmless.—They were wrong.

    THz radiation unzips the DNA molecule

    In a breakthrough study conducted by Dr. Boian Alexandrov at the Center for Nonlinear Studies at Los Alamos National Laboratory in New Mexico and a team of physicists, they discovered terrifying evidence that exposure to THz radiation builds cumulatively and affects human and animal tissue DNA. In essence, it tends to unzip the DNA molecule. [See: Inside TSA scanners: How terahertz waves tear apart human DNA] —-The Los Alamos scientists paper, DNA Breathing Dynamics in the Presence of a Terahertz Field reveals very disturbing—even shocking—evidence that THz radiation significantly damages the DNA of the people being directed through airport scanners and all TSA workers in close proximity to the machines.—Their synopsis: “We consider the influence of a terahertz field on the breathing dynamics of double-stranded DNA. We model the spontaneous formation of spatially localized openings of the damped and driven DNA chain, and find that linear instabilities lead to dynamic dimerization, while true local strand separations require a threshold amplitude mechanism. Based on our results we argue that a specific terahertz radiation exposure may significantly affect the natural dynamics of DNA, and thereby influence intricate molecular processes involved in gene expression and DNA replication.“—What all that means is the resonant effects of the THz waves bombarding humans unzips the double-stranded DNA molecule. This ripping apart of the twisted chain of DNA creates bubbles between the genes that can interfere with the processes of life itself: normal DNA replication and critical gene expression.

    Likely to cause cancer

    David J. Brenner, a Columbia University doctor and expert on the effects of radiation stated that it’s quite likely the TSA scanners will cause cancer in some individuals.—Brenner, whose Columbia’s Center for Radiological Research work focuses on radiation’s effects on biological processes, low exposure risk evaluation and radio-isotopic therapy, is concerened that people with compromised immune systems such as AIDS patients, those suffering from lupus or other immune-deficient ailments are especially at risk. Infants, children up to age 5 or 6, women who are pregnant or lactating, cancer patients and many more should steer far clear of the machines.—

    DNA strand bombarded by THz radiation unzips

    Those exposed to THz radiation—whether from security scanners or future cell phone technology—who are taking certain prescription medications or have significantly low levels of certain vitamins have increased risk of radiation induced carcinomas.——-Repeated exposure to low level radiation scans can also lead to cataracts and bring on skin cancer—including deadly melanoma.—A CMOS chip used in many different products

    THz to utilize existing CMOS chips

    According to the Daily Mail, the chips—created using Complementary Metal-Oxide Semiconductor—or CMOS use the same technology already incorporated into devices like HD TVs, smart phones and personal computers.—Dr. Kenneth O, professor of electrical engineering at the University of Texas at Dallas and leader of the project explained to the Daily Mail that “We’ve created approaches that open a previously untapped portion of the electromagnetic spectrum for consumer use and life-saving medical applications.—“CMOS is affordable and can be used to make lots of chips,” Dr. O said. “The combination of CMOS and terahertz means you could put this chip and receiver on the back of a cellphone, turning it into a device carried in your pocket that can see through objects.”—The team’s findings were presented to an enthusiastic audience at the 2012 International Solid-State Circuits Conference held in San Francisco, California. Next the team plans to create the CMOS terahertz imaging system.

    Before moving ahead with the project, the good doctor and his team might consider contacting Dr. Boian Alexandrov and his team at Los Alamos to compare notes.—It would be a shame if a deadly technology that could eventually kill or sicken millions of people were unknowingly sold across the world. Note: That’s EXACTLY what ‘they’ want . . . more sick people to spend YEARS being ‘cured’ by allopathic medicine using MORE equipment with such technology, and being treated with meds from big pharma, all of which will meet ‘their’ eugenics goals. Treason, abounds!

    http://www.pakalertpress.com/2012/04/29/dna-destroying-chip-being-embedded-into-mobile-phones/?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+pakalert+%28Pak+Alert+Press%29

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    Oral supplementation of turmeric decreases proteinuria, hematuria, and systolic blood pressure in patients suffering from relapsing or refractory lupus nephritis: a randomized and placebo-controlled study.

    J Ren Nutr. 2012 Jan;22(1):50-7—Authors: Khajehdehi P, Zanjaninejad B, Aflaki E, Nazarinia M, Azad F, Malekmakan L, Dehghanzadeh GR

    Abstract
    OBJECTIVE: Despite highly expensive treatments, lupus nephritis remains a major cause of morbidity and mortality in patients with relapsing or refractory lupus nephritis. Meanwhile, experimental studies indicate that curcumin attenuates both the binding of autoantibodies from systemic lupus erythematosus patients to their cognate antigens and also the inflammatory responses of tumor necrosis factor-alpha-stimulated human endothelial cells. Therefore, in this study we investigated effect(s) of oral curcumin supplementation on patients suffering from relapsing or refractory lupus nephritis. DESIGN: A randomized and placebo-controlled study was carried out. SETTING: The present study was conducted in Lupus clinic of Hafez Hospital, Out-Patient Department of Shiraz University of Medical Sciences. PATIENTS: A total of 24 patients with relapsing or refractory biopsy-proven lupus nephritis, who were randomized in 2 groups (trial [n = 12] and control [n = 12] groups) were included in this study. INTERVENTION: With each meal, each patient in the trial group received 1 capsule for 3 months, which contained 500 mg turmeric, of which 22.1 mg was the active ingredient curcumin (3 capsules daily). The control group received 3 capsules (1 with each meal) for the same period, which contained starch and were identical in color and size to capsules given to patients in the trial group. MAIN AUTOMATIC MEASURE: Data were analyzed using Statistical Package for the Social Sciences software version 15.0. RESULTS: A significant decrease in proteinuria [U1]was found when comparing pre- (954.2 ± 836.6) and 1, 2, and 3 months supplementation values (448.8 ± 633.5, 235.9 ± 290.1, and 260.9 ± 106.2, respectively) in the trial group. Also, systolic blood pressure and hematuria [U2]were found to decrease significantly when pre- and post-turmeric supplementation values were compared in the trial group. However, placebo capsules did not exert any statistically significant effect on measured variables in the control group over 3 months of the study. No adverse effect related to turmeric supplementation was observed during the trial. CONCLUSION: Short-term turmeric supplementation can decrease proteinuria, hematuria, and systolic blood pressure in patients suffering from relapsing or refractory lupus nephritis and can be used as an adjuvant safe therapy for such patients. PMID: 21742514 [PubMed – indexed for MEDLINE]

    Special Note Utilize either black pepper or Piperine when using any tumeric or curcumin—or it will not be effective—or extract the tumeric with a black pepper in either alcohol or water and utilize it this way as well

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    Antioxidant-rich watercress shows sports nutrition potential

    Eight weeks of supplementation with watercress may reduce markers of oxidative stress and damage after
    exhaustive exercise, suggests a new study—Healthy men consuming the green leafy vegetable had
    less damage to DNA and lower levels of markers of oxidative stress, a result attributed to
    the high antioxidant of watercress, report researchers from Edinburgh Napier University in Scotland
    and the University of Ulster in Northern Ireland The lipid-soluble antioxidants alpha-tocopherol,
    gamma-tocopherol and xanthophyll were all elevated following supplementation with
    watercress, and, in doing so, indicates the potential for watercress to act as a source of blood-rich
    antioxidants,” wrote the researchers in the British Journal of Nutrition”The increased concentration
    of xanthophyll following the acute dose of watercress may therefore have played a
    contributory role in the increased protection of lymphocyte DNA in this supplemented
    group.” Exercise and oxidative stress Oxygen-breathing organisms naturally produce reactive oxygen
    species (ROS), which play an important role in a range of functions, including cell signaling. However,
    over production of these ROS from smoking, pollution, sunlight, high intensity exercise,
    or simply aging, may overwhelm the body’s antioxidant defenses and lead to oxidative
    stress. “As it has been shown that an over consumption of oral antioxidants may lead
    to a pro-oxidant state, causing a disturbance in redox biochemistry, it is therefore
    imperative that food sources naturally high in antioxidant vitamins are considered,
    due to their capacity to provide increased systemic and cellular protection without
    excessively elevating in vivo antioxidant vitamin concentrations,” explained the researchers.
    In order to test the efficacy of watercress with respect to exhaustive exercise, the researchers recruited
    10 healthy men with an average age of 23 to participate in their eight week study. Participants were
    given 85 grams of watercress to consume every day for eight weeks. They also participated
    in an eight week study with no watercress consumption to act as controls. Results from the exercise
    tests showed that exercise during the no-watercress period led to an increase in DNA damage,
    as well as increases in lipid peroxidation, a marker of oxidative stress. However, such increases
    were not observed during the watercress period, said the researchers. Additionally, blood samples
    revealed increased levels of fat-soluble antioxidants alpha-tocopherol, gamma-tocopherol
    and xanthophylls. Antioxidant effects “In the present investigation, serum [levels of the pro-oxidant
    compound hydrogen peroxide] H2O2 decreased following exhaustive exercise under both supplemented
    conditions but increased in the control groups,” wrote the researchers, led by the University of
    Ulster’s Gareth Davison. “These data would lend support to the suggestion that watercress may provide
    effective in vivo protection against H2O2 production as a function of exercise. It is also plausible
    that the elevated lipid-soluble antioxidants (under both supplemented protocols) are directly scavenging
    superoxide and therefore result in a net decrease in H2O2 production. “The observed increase in
    lipid-soluble antioxidants, as that demonstrated following exercise, may also play a
    key role in the protection against cell membrane lipid peroxidation.” “The study demonstrates
    that exhaustive aerobic exercise may cause DNA damage and lipid peroxidation; however,
    these perturbations are attenuated by either short- or long-term watercress supplementation,
    possibility due to the higher concentration of lipid-soluble antioxidants following
    watercress ingestion.” —Source-http://dx.doi.org/10.1017/S0007114512000992 British Journal
    of Nutrition Published online ahead of print, FirstView Articles, doi–10.1017/S0007114512000992
    “Acute and chronic watercress supplementation attenuates exercise-induced peripheral mononuclear
    cell DNA damage and lipid peroxidation” Authors: M.C. Fogarty, C.M. Hughes, G. Burke, J.C. Brown,
    G.W. Davison

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    The ability of an ethanol extract of Cinnamomum cassia to inhibit inflammatory action.– Src and spleen tyrosine kinase J

    Ethnopharmacol. 2012 Jan 31;139(2):566-73—Authors: Yu T, Lee S, Yang WS, Jang HJ, Lee YJ, Kim TW, Kim SY, Lee J, Cho JY

    Abstract
    ETHNOPHARMACOLOGICAL RELEVANCE: Cinnamomum cassia Blume (Aceraceae) has been traditionally used to treat various inflammatory diseases such as gastritis. However, the anti-inflammatory mechanism of Cinnamomum cassia has not been fully elucidated. This study examined the anti-inflammatory mechanism of 95% ethanol extract (Cc-EE) of Cinnamomum cassia.–MATERIALS AND METHODS: The effect of Cc-EE on the production of inflammatory mediators in RAW264.7 cells and peritoneal macrophages was investigated. Molecular mechanisms underlying the effects, especially inhibitory effects, was elucidated by analyzing the activation of transcription factors and their upstream signaling, and by evaluating the kinase activity of target enzymes.–RESULTS: Cc-EE of Cinnamomum cassia diminished the production of nitric oxide (NO), tumor necrosis factor (TNF)-α, and prostaglandin (PG)E(2), in lipopolysaccharide (LPS)-activated RAW264.7 cells and peritoneal macrophages in a dose-dependent manner. Cc-EE also blocked mRNA expression of inducible NO synthase (iNOS), cyclooxygenase (COX)-2, and TNF-α by suppressing the activation of nuclear factor (NF)-κB, and simultaneously inhibited its upstream inflammatory signaling cascades, including spleen tyrosine kinase (Syk) and Src. Consistent with these findings,.—CONCLUSION: Cc-EE exerts strong anti- the extract directly blocked the kinase activities of Src and Syk inflammatory activity by suppressing Src/Syk-mediated NF-κB activation, which contributes to its major ethno-pharmacological role as an anti-gastritis remedy. Future work will be focused on determining whether the extract can be further developed as an anti-inflammatory drug.–PMID: 22155395 [PubMed – indexed for MEDLINE]

    Recipe for Cinnamon bark—take Cinnamon Bark and add vodka to it in a blender and blend this at high speed—for 10 minutes + then stop blender –strain and use-1/4 tsp as needed

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    Plant Diversity Is Key to Maintaining Productive Vegetation

     

    NSF Cedar Creek LTER site experiments show what makes prairies and forests most productive. –ScienceDaily (May 3, 2012) — Vegetation, such as a patch of prairie or a forest stand, is more productive in the long run when more plant species are present, results of a new study show. The long-term study of plant biodiversity found that each species plays a role in maintaining a productive ecosystem, especially when a long time horizon is considered. The research found that every additional species in a plot contributed to a gradual increase in both soil fertility and biomass production over a 14-year period. This week’s issue of the journal Science published the results. They highlight the importance of managing for diversity in prairies, forests and crops, according to Peter Reich, lead author of the paper and a forest ecologist at the University of Minnesota. Reich and colleagues looked at how the effect of diversity on productivity of plants changed over the long-term.—Two large field experiments were conducted at the National Science Foundation’s (NSF) Cedar Creek Long-Term Ecological Research (LTER) site in Minnesota, one of 26 such NSF LTER sites around the globe in ecosystems from forests to grasslands, tundra to coral reefs.—“This study reveals what short-term experiments have missed: that the effects of biodiversity loss on ecosystems are more complex, severe and unpredictable than previously thought,” says Matt Kane, an NSF LTER program director.-“The work shows the importance of doing long-term research,” says Kane, “in this case documenting for the first time the critical importance of biodiversity for ecosystem health and sustainability.”–The biodiversity experiments at Cedar Creek are the longest-running such experiments in the world, says Reich. They contain plots with one, four, nine or 16 different species of plants.—The research used long-lived prairie plants, but serves as a model system for all vegetation, whether prairie, forest or row crop.-The study also showed how diversity works by demonstrating that different species have different ways of acquiring water, nutrients and carbon–and maintaining them in an ecosystem.–“Prior shorter-term studies, most about two years long, found that diversity increased productivity, but that having more than six or eight species in a plot gave no additional benefit,” Reich says. —–The scientists found that over a 14-year time span, all 16 species in the most diverse plots contributed more and more each year to higher soil fertility and biomass production.-“The take-home message,” says Reich, “is that when we reduce diversity in the landscape–think of a cornfield or a pine plantation or a suburban lawn–we are failing to capitalize on the valuable natural services that biodiversity provides.”-Co-authors of the paper are David Tilman, Forest Isbell, Kevin Mueller, Sarah Hobbie and Nico Eisenhauer of the University of Minnesota, and Dan Flynn of the University of Zurich.–Story Source—The above story is reprinted from materials provided by National Science Foundation. —Journal Reference-P. B. Reich, D. Tilman, F. Isbell, K. Mueller, S. E. Hobbie, D. F. B. Flynn, N. Eisenhauer. Impacts of Biodiversity Loss Escalate Through Time as Redundancy Fades. Science, 2012; 336 (6081): 589 DOI: 10.1126/science.1217909

     

     

    TOP D

    [U1]proteinuria from protein and urine) means the presence of an excess of serum proteins in the urine
    [U2]In medicine, hematuria, or haematuria, is the presence of red blood cells (erythrocytes) in the urine. It may be idiopathic and/or benign, or it can be a sign that there is a kidney stone or a tumor in the urinary tract (kidneys, ureters, urinary bladder, prostate, and urethra), ranging from trivial to lethal

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    Show of the Week May 21-2012

    Community-Acquired MRSA Is Spreading

     

    Blue Light Destroys Antibiotic-Resistant Staph Infection

     

    Clustering MRSA in Europe Indicates Diffusion Through Regional Health-Care Networks

     

    Overcrowding And Understaffing In Hospitals Increases Levels Of MRSA Infections

     

    Cross-Reactivity Between Peanuts and Other Legumes Can Lead to Serious Allergic Reactions

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    Community-Acquired MRSA Is Spreading

    ScienceDaily (Mar. 31, 2008) — Drug resistant hospital superbugs like MRSA have been kept under control in Denmark for more than 30 years. But the latest reports say that in the last 10 years MRSA cases have risen 10 times as new strains of bacteria with resistance genes spread through the community, scientists heard April 1 2008 at the Society for General Microbiology’s 162nd meeting.—“The new threat is MRSA transmission in the community, without infected people visiting a hospital or care home themselves, where they might be expected to risk contact with drug resistant bacteria”, says Professor Robert Skov from the Statens Serum Institut in Copenhagen, Denmark.—-“The spread of community acquired MRSA among the general population creates a huge problem for us”, says Professor Skov. “Some infected people will inevitably be hospitalised themselves, or visit friends and relatives who are patients in hospitals. Or they could be health care workers and so will increase the risk of outbreaks of these new types of MRSA. These community strains have evolved independently of the hospital strains and so present a whole new series of problems for control and treatment”.—Staphylococcus aureus is common and usually harmless, it is carried by 25-40% of the population on their skin and in their noses. But if it gets inside the body through an injury, cut, surgical operation or through a catheter it can cause infections. These infections are often mild, causing boils or pimples, but in some cases they may develop into more serious infections affecting the bloodstream, joints and bones.—These serious infections were first brought under control with the discovery of penicillin, but as resistance to antibiotics has spread, new and dangerous superbug strains such as MRSA have emerged. These are far more difficult to treat and can cause life-threatening infections, especially in patients with impaired immune systems or low white blood cell counts.–[U1]”We have managed to hold the frequency of MRSA cases down to under one per cent in Denmark for over 30 years. But in 1997 we recognised the first cases of community acquired MRSA, a new strain independent of hospital and nursing home contacts, in a young adult and two families in a rural town”, says Professor Skov. “From the families we traced the superbug being transmitted through a kindergarten, a school, a factory and a farm. Between 1999 and 2006 the number of community acquired MRSA infections increased from 11 to 175 a year, making up more than 22% of all MRSA infections, as a rising proportion.”—The Danish scientists found that the most common method of superbug transmission was from one family member to another, with children and younger adults most affected. And many of the infected families had relations in other countries with a high incidence of MRSA in the population.[U2]–The Danish health system responded by introducing new national guidelines in November 2006 designed to prevent MRSA spreading, including increased barrier precautions and isolation nursing in both hospitals and nursing homes. The guidelines appear to be successful, as a small decrease in cases has been observed. The results of these experiences, which have helped to stop the rising epidemic of MRSA, will be published in health journals shortly.—Story Source–The above story is reprinted from materials provided by Society for General Microbiology,

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    Blue Light Destroys Antibiotic-Resistant Staph Infection

    ScienceDaily (Jan. 29, 2009) — Two common strains of methicillin-resistant Staphylococcus aureus, commonly known as MRSA, were virtually eradicated in the laboratory by exposing them to a wavelength of blue light, in a process called photo-irradiation.—Antibiotic-resistant bacterial infections represent an important and increasing public health threat. At present, fewer than 5% of staphylococcal strains are susceptible to penicillin, while approximately 40%-50% of Staph aureus isolated have developed resistance to newer semisynthetic antibiotics such as methicillin as well.—-Chukuka S. Enwemeka, Deborah Williams, Sombiri K. Enwemeka, Steve Hollosi, and David Yens from the New York Institute of Technology (Old Westbury, NY) had previously demonstrated that photo-irradiation using 405-nm light destroys MRSA strains grown in culture. In the current study, “Blue 470-nm Light Kills Methicillin-Resistant Staphylococcus aureus (MRSA) in Vitro,” the authors exposed bacterial colonies of MRSA to various doses of 470-nm light, which emits no UV radiation.—–The two MRSA populations studied—the US-300 strain of CA-MRSA and the IS-853 strain of HA-MRSA—represent prominent community-acquired and hospital-acquired strains, respectively.—The authors report that the higher the dose of 470-nm blue light, the more bacteria were killed. High-dose photo-irradiation was able to destroy 90.4% of the US-300 colonies and the IS-853 colonies. The effectiveness of blue light in vitro suggests that it should also be effective in human cases of MRSA infection, and particularly in cutaneous and subcutaneous infections.—“It is inspiring that an inexpensive naturally visible wavelength of light can eradicate two common strains of MRSA. Developing strategies that are capable of destroying MRSA, using mechanisms that would not lead to further antibiotic resistance, is timely and important for us and our patients,” says Chukuka S. Enwemeka, PhD, FACSM, Co-Editor-in-Chief of the Journal and first author of the study.—The article will appear in the April 2009 issue (Volume 27, Number 2) of the peer-reviewed journal Photomedicine and Laser Surgery. —-Story Source-The above story is reprinted from materials provided by Mary Ann Liebert, Inc./Genetic Engineering News.

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    Clustering MRSA in Europe Indicates Diffusion Through Regional Health-Care Networks

     

    ScienceDaily (Jan. 11, 2010) — A new study finds that methicillin-resistant Staphylococcus aureus (MRSA) -responsible for several difficult-to-treat infections including blood poisoning and pneumonia and a particular problem in hospitals — occurs in distinct geographical clusters across Europe, indicating that MRSA is being diffused by patients moving between hospitals rather than spreading freely in the community.—The study, published in PLoS Medicine, used an interactive Web tool to map different strains of the Staphylococcus aureus (S. aureus) bacterium across the continent.—-MRSA infections have become more prevalent in hospitals over the past ten years, and information about its geographical distribution could help us to understand how it spreads and how to control it.—In 2006 Hajo Grundmann, of the University Medical Centre in Groningen in the Netherlands, and colleagues assembled a large group of collaborators in 450 European hospitals located in 26 different countries. These hospitals collected both MRSA and methicillin-sensitive S. aureus (MSSA) isolates from infected patients — MRSA emerges when MSSA clones acquire resistance to antibiotics. National laboratories identified specific strains of S. aureus by molecular typing and entered this information into a Web-based mapping application which is publicly available (http://www.spatialepidemiology.net/srl-maps).—The results show that strains of MRSA tend to cluster within regional borders and, in several instances, were associated with individual hospitals. This suggests that MRSA is mainly spread by patients who are repeatedly admitted to different hospitals. “Control efforts aimed at interrupting the spread within and between health care institutions may not only be feasible but ultimately successful,” conclude the researchers.—Franklin Lowy of Columbia University — uninvolved in the research — discusses the study in a Perspective and suggests that it “illustrates the ability of spatial mapping techniques to help understand the spread of new or re-emerging pathogens at the local as well as the international level”—Story Source–The above story is reprinted from materials provided by Public Library of Science, via EurekAlert!, a service of AAAS. —Journal References–Grundmann H, Aanensen DM, van den Wijngaard CC, Spratt BG, Harmsen D, et al. Geographic Distribution of Staphylococcus aureus Causing Invasive Infections in Europe: A Molecular-Epidemiological Analysis. PLoS Medicine, 2010; 7 (1): e1000215 DOI: 10.1371/journal.pmed.1000215—Lowy FD. Mapping the Distribution of Invasive Staphylococcus aureus across Europe. PLoS Medicine, 2010; 7 (1): e1000205 DOI: 10.1371/journal.pmed.1000205

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    Overcrowding And Understaffing In Hospitals Increases Levels Of MRSA Infections

     

    A new study found that overcrowding and understaffing caused higher levels of MRSA because of its impact on hand hygiene, the number of contacts between healthcare workers and different patients, overburdening of screening and isolation programmes and by causing staff burnout.

    ScienceDaily (June 24, 2008) — A review article authored by a University of Queensland academic has found overcrowding and understaffing in hospitals are two key factors in the transmission of MRSA (Meticillin — Resistant Staphylococcus Aureus) infections worldwide.—Dr Archie Clements, from the School of Population Health, reported overcrowding and understaffing increased levels of MRSA infections, which lead to increased inpatient hospital stay, bed blocking, overcrowding and more MRSA infections.—The review included information from 140 papers and Dr Clements was part of a team of seven authors.–The article titled: Overcrowding and understaffing in modern health-care systems: key determinants in Meticillin-Resistant Staphylococcus Aureus (MRSA) transmission, was published today in the July edition of The Lancet Infectious Diseases.—Dr Clements said MRSA was an antibiotic-resistant type of Staphylococcus Aureus, a common bacteria present on the skin and in the nostrils of many healthy people.–“MRSA often colonises hospital patients to no ill effect but, if present in a surgical wound or carried to the bloodstream by an intravenous catheter, it can cause serious infection and possibly the death of the patient,” he said.—Dr Clements said overcrowding and understaffing caused higher levels of MRSA because of its impact on hand hygiene, the number of contacts between healthcare workers and different patients, overburdening of screening and isolation programmes and by causing staff burnout.—“MRSA worsens overcrowding because patients with MRSA stay longer in hospitals and, if isolation in multi-bed rooms is done, beds not occupied by the MRSA patient are also closed to other patients,” he said.–“Overcrowding and understaffing, root causes of the MRSA problem, are partly related to policy that promotes high patient throughput and fewer beds, and partly to a diminishing, ageing health care workforce.—“These problems are likely to continue or worsen, and impact on patient health and safety, unless new ways are found to reduce overcrowding and understaffing of hospitals.”—Dr Clements hoped to use the findings to initiate more research into the relationship between overcrowding/understaffing and MRSA to answer questions such as: “What are the optimal bed occupancy and staffing rates for preventing avoidable MRSA infections while maintaining current levels of care?” and “What is the likely impact of MRSA interventions under conditions of overcrowding and understaffing?”—Story Source-The above story is reprinted from materials provided by University of Queensland.

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    Cross-Reactivity Between Peanuts and Other Legumes Can Lead to Serious Allergic Reactions

     

    ScienceDaily (May 15, 2012) — Food allergies pose a serious and growing problem in the West. Many foods can lead to allergic reactions and this situation is further complicated by so-called cross-reactions, whereby an allergy to one particular food can trigger allergic reactions to another food. There are no treatments available for food allergies[U3], but the establishment of two mouse models can be used to develop and test new forms of treatment, for example vaccines.[U4]—Around 4-8% of children and 1-4% of adults in the West suffer from food allergy. The most common causes of food allergy are peanuts, nuts, soya, milk, fish, shellfish, flour and eggs, but a total of over 170 different foods have been found to result in allergic reactions. In addition, there are the allergies that arise as a result of cross reactions to other types of food. The only form of treatment is to avoid all consumption of the food that the person is allergic to. Allergenic substances that are hidden in processed foods therefore pose a particular problem for people allergic to foods.—-Nina E. Vinje’s doctoral research has led to the establishment of two mouse models for food allergy to the legumes lupin and Fenugreek (Trigonella foenum-graecum). These models have been used to test whether legumes such as soya, peanuts, Fenugreek and lupin can trigger allergic reactions in mice that are already allergic to lupin and Fenugreek respectively. It is important to establish good animal models for food allergies because the development of an allergic immune response depends on a complicated interaction between types of cells in several different organs. Vinje has made every effort to reduce the use of laboratory animals to a minimum during her project. For this reason, she used an advanced statistical method to develop the models in order to gain as much information as possible from the use of as few animals as possible.—Lupin and Fenugreek are examples of so-called “new” and “hidden” allergens which have been introduced to Norway, for instance in ready-made meals, over the last 10-15 years. Lupin was introduced as a supplement to wheat flour in various bakery products because of its ability to promote good baking. Fenugreek is used as an ingredient in foods such as curry, chutney and spiced tea and is well known in Asian dishes. Packaging often does not show whether Fenugreek is an ingredient, as the consumer information merely says “spices.” Both lupin and Fenugreek can lead to serious cross-reactions in patients with peanut allergy, in contrast to other legumes such as soya and peas. This fact was discovered due to messages sent in to the Food Allergy Register (www.fhi.no/matallergireg) and these discoveries contributed to the EU making it obligatory to mark lupin as an ingredient in foods.—The established mice models can be used to try out new treatments, for example vaccines against food allergies[U5]. A vaccine must be tested on animals before it can be tested on humans, both in order to find out whether it works and to make sure that it does not cause serious side effects. New foods that are to be released onto the market will also be able to be tested to see if they can cause allergies. Mice can be used for this purpose because their immune system is well charted and is relatively similar to that of humans. This means that researchers can study the clinical, anaphylactic (shock) reactions associated with food allergy in mice in order to gain a greater understanding of the mechanisms that cause allergic reactions in humans.—Vinje’s doctoral project was carried out at the Norwegian Institute of Public Health and researchers and fellows at the Norwegian Veterinary Institute and the Norwegian School of Veterinary Science have been major collaborators.–Story Source-The above story is reprinted from materials provided by Norwegian School of Veterinary Science, via AlphaGalileo.

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    TOP E

    [U1]This is easily achieved today with the chemtrail dropping exhausting our immune system and allow for the low white blood cell counts to take place allowing a inept pathogen to become excessively dangerious—as a result of this Genetic engineering of dis eases-we will see a considerably amount of infection taking place with the youth and elderly primarily—which will either be precriibed with drugs that will be ineffective or the elderly eill be euphanized with a vaccine
    [U2]So it is not genetic but rather a concentrated infecting of family or groups or communities which would mean a specific group of people would be infected and whole bloodlines could be wiped
    [U3]Amazing—when you read this —this would basically tell you the way people are consuming there foods and the combinations —are the issue—when we combine the GMO which compromises DNA and genes in the human body and then further combine the different foods tat are genetically modified we are getting a response to the debilitating of the immune system and digestive system not to mention the other system impacted or exasperated to remove these
    [U4]Notice how quick to mention a vaccine rather then a technique or life style to change!!!??
    [U5]Never Changes –instead of a change to a higher quality of food in the supermarket and apply a little self discipline—You may be surprised to the increase in health

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    Show of the Week May 25-2012

     

    Smart meters pose health hazard

     

    A Moderate acute increase in physical activity enhances nutritive flow and the muscle protein

    anabolic response

     

    Fructose The Saboteur of Brain

     

    Eating High Levels Of Fructose Impairs Memory In Rats

     

    Butter differs from olive oil and sunflower oil in its effects on postprandial lipemia and triacylglycerol

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    Smart meters pose health hazard

    Montreal Gazette Montreal Gazette –

    Hydro-Québec’s proposed rollout of 3.8 million wireless smart meters “may constitute a risk of serious, as well as irreversible, damage to health,” according to a report by a U.S. public health professional testifying before Quebec’s energy board Thursday.—David Carpenter, director of the University at Albany’s Institute for Health and the Environment, urged that precautionary measures be taken to offset potential health problems related to radiofrequency emissions from the wireless meters.—There hasn’t yet been a comprehensive study on the impact of the relatively new devices and their RF radiation on human health, Carpenter told the board.—While the body of evidence is incomplete, it “is strong enough that as a public health official it is my responsibility to tell you that we should do what we can to reduce exposure in ways that are neither excessively expensive or excessively regulatory,” he said.—-“If government does not acknowledge that there is reason for caution, it will be like the situation we had with smoking and lung cancer.”–The meters that Hydro-Québec proposes to use in its $1-billion project to deploy smart meters across the province by 2017 would be mostly located on exterior walls.—But meters situated inside occupied rooms such as kitchens would increase exposure to RF energy that would be especially problematic for children, according to Carpenter’s report and testimony Thursday.—In a report filed with the Régie de l’énergie, Carpenter said that alternatives include hardwired technology.-Meters inside homes should be moved to the outside or at least positioned so that they don’t face occupants.–Carpenter was retained by the Association québécoise de lutte contre la pollution atmosphérique and Stratégies Énergétiques, both intervenors in the case. Carpenter was not accorded the status of an expert witness by board president Richard Lassonde on Thursday.–Lassonde accepted Hydro-Québec’s key position that Carpenter had not himself done research directly related to RF radiation.–Carpenter, whose curriculum vitae runs to 32 pages, is the former director of the third-largest public health lab in the U.S., testified about RF and power-line emissions and cancer before the U.S. President’s Cancer Panel in 2009 and is among the external reviewers of grant proposals for Quebec’s cancer program.The hearings continue.

    lmoore@montrealgazette.com

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    A moderate acute increase in physical activity enhances nutritive flow and the muscle protein anabolic response to mixed nutrient intake in older adults

    Kyle L Timmerman, Shaheen Dhanani, Erin L Glynn, Christopher S Fry, Micah J Drummond, Kristofer Jennings, Blake B Rasmussen, and Elena Volpi
    + Author Affiliations

    1From the Departments of Nutrition & Metabolism (KLT, MJD, and BBR), Internal Medicine (EV), and Preventive Medicine and Community Health (KJ); Sealy Center on Aging (KLT, SD, MJD, BBR, and EV); Division of Rehabilitation Sciences (KLT, ELG, CSF, MJD, and BBR); and the Institute for Translational Sciences (KLT, MJD, BBR, and EV), University of Texas Medical Branch, Galveston, TX.
    + Author Notes

    ↵2 Supported by NIH R01 AG018311, P30 AG024832, S10 RR16650, T32 HD07539, and UL1 RR029876. Definity was provided by Lantheus Medical Imaging, North Billerica, MA, under Definity Research grant no. 26020.
    ↵3 Address correspondence to E Volpi, 301 University Boulevard, Galveston, TX 77555-0460. E-mail: evolpi@utmb.edu.
    Abstract

    Background: Nutrient stimulation of muscle protein anabolism is blunted with aging and may contribute to the development and progression of sarcopenia in older adults. This is likely due to insulin resistance of protein metabolism and/or endothelial dysfunction with a reduction in nutritive flow, both of which can be improved by aerobic exercise. –Objective: Our objective was to determine whether increasing physical activity can enhance the muscle protein anabolic effect of essential amino acid (EAA) + sucrose intake in older subjects by improving nutritive flow and/or insulin signaling. –Design: Using a randomized crossover design, we measured in older subjects [n = 6, 70 ± 3 y of age, BMI (in kg/m2) of 25 ± 1] the acute effects of increasing physical activity with aerobic exercise, as compared with normal sedentary lifestyle, on the response of blood flow, microvascular perfusion, insulin signaling, and muscle protein kinetics to EAA+sucrose intake. –Results: No differences between treatment groups were found in the basal state[U1]. The change from the basal state in blood flow, muscle perfusion, phenylalanine delivery, net balance, and muscle protein synthesis during the consumption of EAA+sucrose was significantly higher after the exercise than after the control treatment (P < 0.05). Insulin signaling increased during EAA+sucrose ingestion in both groups (P < 0.05). –Conclusions: Our data indicate that a prior bout of aerobic exercise increases the anabolic effect of nutrient intake in older adults. This effect appears to be mediated by an exercise-induced improvement in nutrient-stimulated vasodilation and nutrient delivery to muscle rather than to improved insulin signaling. This trial was registered at clinicaltrials.gov as NCT00690534.

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    Fructose The Saboteur of Brain

     

    This Is Your Brain On Sugar– Study in Rats Shows High-Fructose Diet Sabotages Learning, Memory—New research suggests that binging on soda and sweets for as little as six weeks may make you stupid. —ScienceDaily (May 15, 2012) — Attention, college students cramming between midterms and finals: Binging on soda and sweets for as little as six weeks may make you stupid.——A new UCLA rat study is the first to show how a diet steadily high in fructose slows the brain, hampering memory and learning — and how omega-3 fatty acids can counteract the disruption. The peer-reviewed Journal of Physiology publishes the findings in its May 15 edition.—“Our findings illustrate that what you eat affects how you think,” said Fernando Gomez-Pinilla, a professor of neurosurgery at the David Geffen School of Medicine at UCLA and a professor of integrative biology and physiology in the UCLA College of Letters and Science. “Eating a high-fructose diet over the long term alters your brain’s ability to learn and remember information. But adding omega-3 fatty acids to your meals can help minimize the damage.[U2]”–While earlier research has revealed how fructose harms the body through its role in diabetes, obesity and fatty liver, this study is the first to uncover how the sweetener influences the brain.—The UCLA team zeroed in on high-fructose corn syrup, an inexpensive liquid six times sweeter than cane sugar, that is commonly added to processed foods, including soft drinks, condiments, applesauce and baby food. The average American consumes more than 40 pounds of high-fructose corn syrup per year, according to the U.S. Department of Agriculture. “We’re not talking about naturally occurring fructose in fruits, which also contain important antioxidants,” explained Gomez-Pinilla, who is also a member of UCLA’s Brain Research Institute and Brain Injury Research Center. “We’re concerned about high-fructose corn syrup that is added to manufactured food products as a sweetener and preservative.”—Gomez-Pinilla and study co-author Rahul Agrawal, a UCLA visiting postdoctoral fellow from India, studied two groups of rats that each consumed a fructose solution as drinking water for six weeks. The second group also received omega-3 fatty acids in the form of flaxseed oil and docosahexaenoic acid (DHA[U3]), which protects against damage to the synapses — the chemical connections between brain cells that enable memory and learning.[U4]—“DHA is essential for synaptic function — brain cells’ ability to transmit signals to one another,” Gomez-Pinilla said. “This is the mechanism that makes learning and memory possible. Our bodies can’t produce enough DHA, so it must be supplemented through our diet.”–The animals were fed standard rat chow and trained on a maze twice daily for five days before starting the experimental diet. The UCLA team tested how well the rats were able to navigate the maze, which contained numerous holes but only one exit. The scientists placed visual landmarks in the maze to help the rats learn and remember the way. — Six weeks later, the researchers tested the rats’ ability to recall the route and escape the maze. What they saw surprised them.—-“The second group of rats navigated the maze much faster than the rats that did not receive omega-3 fatty acids,” Gomez-Pinilla said. “The DHA-deprived animals were slower, and their brains showed a decline in synaptic activity. Their brain cells had trouble signaling each other, disrupting the rats’ ability to think clearly and recall the route they’d learned six weeks earlier.”—The DHA-deprived rats also developed signs of resistance to insulin, a hormone that controls blood sugar and regulates synaptic function in the brain. A closer look at the rats’ brain tissue suggested that insulin had lost much of its power to influence the brain cells.—“Because insulin can penetrate the blood-brain barrier, the hormone may signal neurons to trigger reactions that disrupt learning and cause memory loss,” Gomez-Pinilla said.—He suspects that fructose is the culprit behind the DHA-deficient rats’ brain dysfunction. Eating too much fructose could block insulin’s ability to regulate how cells use and store sugar for the energy required for processing thoughts and emotions.—“Insulin is important in the body for controlling blood sugar, but it may play a different role in the brain, where insulin appears to disturb memory and learning,” he said. “Our study shows that a high-fructose diet harms the brain as well as the body. This is something new.”–Gomez-Pinilla, a native of Chile and an exercise enthusiast who practices what he preaches, advises people to keep fructose intake to a minimum and swap sugary desserts for fresh berries and Greek yogurt, which he keeps within arm’s reach in a small refrigerator in his office. An occasional bar of dark chocolate that hasn’t been processed with a lot of extra sweetener is fine too, he said.—Still planning to throw caution to the wind and indulge in a hot-fudge sundae? Then also eat foods rich in omega-3 fatty acids, like salmon, walnuts and flaxseeds, or take a daily DHA capsule. Gomez-Pinilla recommends one gram of DHA per day.–“Our findings suggest that consuming DHA regularly protects the brain against fructose’s harmful effects,” said Gomez-Pinilla. “It’s like saving money in the bank. You want to build a reserve for your brain to tap when it requires extra fuel to fight off future diseases.”—The UCLA study was funded by the National Institute of Neurological Disorders and Stroke. Gomez-Pinilla’s lab will next examine the role of diet in recovery from brain trauma.-Story Source–The above story is reprinted from materials provided by University of California, Los Angeles (UCLA), Health Sciences, via Newswise. —Journal Reference—R. Agrawal, F. Gomez-Pinilla. ‘Metabolic syndrome’ in the brain: deficiency in omega-3 fatty acid exacerbates dysfunctions in insulin receptor signalling and cognition. The Journal of Physiology, 2012; 590 (10): 2485 DOI: 10.1113/jphysiol.2012.230078

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    Eating High Levels Of Fructose Impairs Memory In Rats

    Diets high in fructose — a type of sugar found in most processed foods and beverages — impaired the spatial memory of adult rats—ScienceDaily (July 16, 2009) — Researchers at Georgia State University have found that diets high in fructose — a type of sugar found in most processed foods and beverages — impaired the spatial memory of adult rats.—Amy Ross, a graduate student in the lab of Marise Parent, associate professor at Georgia State’s Neuroscience Institute and Department of Psychology, fed a group of Sprague-Dawley rats a diet where fructose represented 60 percent of calories ingested during the day.—She placed the rats in a pool of water to test their ability to learn to find a submerged platform, which allowed them to get out of the water. She then returned them to the pool two days later with no platform present to see if the rats could remember to swim to the platform’s location.-“What we discovered is that the fructose diet doesn’t affect their ability to learn,” Parent said. “But they can’t seem to remember as well where the platform was when you take it away. They swam more randomly than rats fed a control diet.”—Fructose, unlike another sugar, glucose, is processed almost solely by the liver, and produces an excessive amount of triglycerides [U5]— fat which get into the bloodstream. Triglycerides can interfere with insulin signaling in the brain, which plays a major role in brain cell survival and plasticity, or the ability for the brain to change based on new experiences.—Results were similar in adolescent rats, but it is unclear whether the effects of high fructose consumption are permanent, she said.—Parent’s lab works with Timothy Bartness, Regents’ Professor of Biology, and John Mielke of the University of Waterloo in Waterloo, Ontario, Canada to examine how diet influences brain function.—Although humans do not eat fructose in levels as high as rats in the experiments, the consumption of foods sweetened with fructose — which includes both common table sugar, fruit juice concentrates, as well as the much-maligned high fructose corn syrup — has been increasing steadily. High intake of fructose is associated with numerous health problems, including insulin insensitivity, type II diabetes, obesity and cardiovascular disease.—“The bottom line is that we were meant to have an apple a day as our source of fructose,” Parent said. “And now, we have fructose in almost everything.” Moderation is key, as well as exercise, she said.—Exercise is a next step in ongoing research, and Parent’s team will investigate whether exercise might mitigate the memory effects of high fructose intake. Her lab is also researching whether the intake of fish oil can prevent the increase of triglycerides and memory deficits. Results from that research will be presented by her graduate student Emily Bruggeman at the 2009 Society for Neuroscience meeting in Chicago this fall.–Story Source-The above story is reprinted from materials provided by Georgia State University.

     

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    Butter differs from olive oil and sunflower oil in its effects on postprandial lipemia and triacylglycerol-rich lipoproteins after single mixed meals in healthy young men.

    Mekki N, Charbonnier M, Borel P, Leonardi J, Juhel C, Portugal H, Lairon D.

    Source—Unité 476-Institut National de la Santé et de la Recherche Médicale, Human Nutrition and Lipids, National Institute of Health and Medical Research, Université de la Méditerranée, 13009 Marseille, France.

    Abstract—-Accumulation of postprandial triacylglycerol-rich lipoproteins is generated by assimilation of ingested dietary fat and has been increasingly related to atherogenic risk. Nevertheless, the influence of different kinds of dietary fatty acids on postprandial lipid metabolism is not well established, except for (n-3) polyunsaturated long-chain fatty acids. Our goal was to evaluate the effects of test meals containing a common edible fat source of saturated (butter), monounsaturated (olive oil) or (n-6) polyunsaturated (sunflower oil) fatty acids on postprandial lipid and triacylglycerol-rich lipoprotein responses. After a 12-h fast, 10 healthy young men ingested mixed meals containing 0 g (control) or 40 g fat, provided as butter, olive oil or sunflower oil in a random order.[U6] Fasting and postmeal blood samples were collected for 7 h. The no-fat test meal did not elicit any change over baseline except for plasma phospholipids, insulin and nonesterified fatty acids. Conversely, the three fat-containing meals elicited bell-shaped postprandial changes (P < 0.05) in serum triacylglycerols, free and esterified cholesterol, and nonesterified fatty acids. The butter meal induced a lower postprandial rise of triacylglycerols in serum and chylomicrons (incremental AUC, mmol.h/L: 0.72) than the two unsaturated oils (olive oil: 1.6, sunflower oil: 1.8), which did not differ. Circulating chylomicrons were smaller after the butter meal than after the two vegetable oil meals. The in vitro susceptibility of circulating chylomicrons to hydrolysis by postheparin plasma was higher after sunflower oil than after butter or olive oil. We conclude that butter results in lower postprandial lipemia and chylomicron accumulation in the circulation of young men than olive or sunflower oils after consumption of a single mixed meal.

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    TOP F

     

    [U1]No difference in a state of rest—both the same –due to both are doing the same thing–Nothing
    [U2]Minimizing damage??? Is this stupid as well—if you know this is causing brain impediment then the best cource is not to consume—the issue is the addictive nature of HFCS or Corn Sugar as it is called these days
    [U3]Flax seed would be acceptable—algae source as well—Avoid the fish oils and utilize the 3’s with 6 and nine—never utilize them sepreately
    [U4]You can as well utilize wheatgerm oil and Sunflower Lecithin
    [U5]NOTICE HERE SUGAR Not Fat triggers Triglycerides—not cholesterol
    [U6]The procedure they used to get there conclusions

     

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    Show of the Week May 28-2012

     

    Genetic Mutation in African Malaria Parasite Shown to Give Resistance to Best Drugs

     

    Interactions Between Species: Powerful Driving Force Behind Evolution?

     

    Antiviral activity of phytochemicals: a comprehensive review

     

    Effects of a nutrient mixture on infectious properties

     

    Nutrient mixture containing ascorbic acid, green tea extract and amino acids suppression of influenza A virus

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    Genetic Mutation in African Malaria Parasite Shown to Give Resistance to Best Drugs

     

    ScienceDaily (Apr. 27, 2012) — Scientists have identified genetic mutations[U1] in the deadliest malaria parasite in Africa that are giving it resistance to one of the most powerful anti-malarial drugs. The researchers say their findings are a further warning that the best weapons against malaria could become obsolete.–The artemisinin group of drugs are the most effective and widely used treatments for malaria. They are most powerful and less likely to be resisted by the malaria parasite when used with other drugs as artemisinin-based combination therapies (ACTs). But the new study confirms previous suggestions that mutations in a key part of the parasite can provide resistance to artemether, one of the two most effective artemisinins.—The research group, led by a team at St George’s, University of London, discovered artemether resistance in parasite samples taken from 11 of the 28 malaria-infected patients in the study. On average, artemether’s effectiveness was reduced by half. Each parasite was found to have the same genetic mutations.[U2]—The patients were infected by malaria parasite-carrying mosquitoes while travelling abroad, mostly in sub-Saharan Africa, home to 90 per cent of the one million people killed worldwide each year by malaria.—Study lead Professor Sanjeev Krishna said: “Artemether and ACTs are still very effective, but this study confirms our fears of how the parasite is mutating to develop resistance. Drug resistance could eventually become a devastating problem in Africa, and not just in south east Asia where most of the world is watching for resistance. Effective alternative treatments are currently unaffordable for most suffering from malaria[U3]. Finding new drugs is, therefore, crucial.” In the study, published online April 27, 2012 in BioMed Central’s open access journal Malaria Journal, the researchers tested samples from patients infected with the Plasmodium falciparum parasite. This parasite causes the deadliest form of malaria, and is responsible for nine out of 10 malaria deaths. [U4]The parasites were assessed for their sensitivity to four artemisinins — artemisinin itself, artemether, dihydroartemisinin and artesunate.—The 11 parasites showing artemether resistance had the same genetic mutations in an internal system called the calcium pump. This is used to transport calcium, crucial for the parasite to function. The researchers already suspected that the calcium pump — which they first showed was a target for artemisinins to work on in 2003 — had the potential to develop artemisinin resistance. But this had been difficult to confirm until now.—Artemether resistance was strongest in several cases where a separate mutation in another transport system — a protein called pfmdr1, already associated with drug resistance — also occurred.—The effectiveness of the other artemisinins was not significantly affected by the mutations. This may be because they were able to work on other transport systems in the parasite, compensating for the effects of resistance mutations in the calcium pump.—However, Professor Krishna added: “At the moment, we do not know if the other artemisinins will follow suit, but given the shared chemistry they have with artemether it is tempting to think that they would.”—He added that resistance could be a result of the increasing use of ACTs, 300 million doses of which were dispensed worldwide in 2011. Greater use could offer the parasites more opportunities to develop genetic mutations that provide resistance. This could, the researchers say, lead to a repeat of how the parasite developed resistance to pre-artemisinin drugs such as chloroquine. Incorrect use of anti-malarials, such as not completing the treatment course or taking sub-standard drugs, could aid this process.—Professor Krishna said: “New drug development is paramount, but it is vital that we also learn more about how artemisinins work so we can tailor ACT treatments to be effective for as long as possible.”—-Story Source-The above story is reprinted from materials provided by University of St George’s London, via AlphaGalileo. –Journal Reference-Dylan R Pillai, Rachel Lau, Krishna Khairnar, Rosalba Lepore, Allegra Via, Henry M Staines, Sanjeev Krishna. Artemether resistance in vitro is linked to mutations in PfATP6 that also interact with mutations in PfMDR1 in travellers returning with Plasmodium falciparum infections. Malaria Journal, 2012; 11 (1): 131 DOI: 10.1186/1475-2875-11-131

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    Interactions Between Species: Powerful Driving Force Behind Evolution?

     

    Computer rendering of virus particles. In a new study, researchers used fast-evolving viruses to observe hundreds of generations of evolution. They found that for every viral strategy of attack, the bacteria would adapt to defend itself, which triggered an endless cycle of co-evolutionary change. —ScienceDaily (Feb. 25, 2010) — Scientists at the University of Liverpool have provided the first experimental evidence that shows that evolution is driven most powerfully by interactions between species, rather than adaptation to the environment.—The team observed viruses as they evolved over hundreds of generations to infect bacteria. They found that when the bacteria could evolve defences, the viruses evolved at a quicker rate and generated greater diversity, compared to situations where the bacteria were unable to adapt to the viral infection.–The study shows, for the first time, that the American evolutionary biologist Leigh Van Valen was correct in his ‘Red Queen Hypothesis’. The theory, first put forward in the 1970s, was named after a passage in Lewis Carroll’s Through the Looking Glass in which the Red Queen tells Alice, ‘It takes all the running you can do to keep in the same place’. This suggested that species were in a constant race for survival and have to continue to evolve new ways of defending themselves throughout time.—Dr Steve Paterson, from the University’s School of Biosciences, explains: “Historically, it was assumed that most evolution was driven by a need to adapt to the environment or habitat. The Red Queen Hypothesis challenged this by pointing out that actually most natural selection will arise from co-evolutionary interactions with other species, not from interactions with the environment.—“This suggested that evolutionary change was created by ‘tit-for-tat’ adaptations by species in constant combat. This theory is widely accepted in the science community, but this is the first time we have been able to show evidence of it in an experiment with living things.”—Dr Michael Brockhurst said: “We used fast-evolving viruses so that we could observe hundreds of generations of evolution. We found that for every viral strategy of attack, the bacteria would adapt to defend itself, which triggered an endless cycle of co-evolutionary change. We compared this with evolution against a fixed target, by disabling the bacteria’s ability to adapt to the virus.–“These experiments showed us that co-evolutionary interactions between species result in more genetically diverse populations, compared to instances where the host was not able to adapt to the parasite. The virus was also able to evolve twice as quickly when the bacteria were allowed to evolve alongside it.”—The team used high-throughput DNA sequencing technology at the Centre for Genomic Research to sequence thousands of virus genomes. The next stage of the research is to understand how co-evolution differs when interacting species help, rather than harm, one another.—-The research is published in Nature and was supported by funding from the Natural Environment Research Council (NERC); the Wellcome Trust; the European Research Council and the Leverhulme Trust.—-Story Source-The above story is reprinted from materials provided by University of Liverpool, via EurekAlert!, a service of AAAS. –Journal Reference–Steve Paterson, Tom Vogwill, Angus Buckling, Rebecca Benmayor, Andrew J. Spiers, Nicholas R. Thomson, Mike Quail, Frances Smith, Danielle Walker, Ben Libberton, Andrew Fenton, Neil Hall & Michael A. Brockhurst. Antagonistic coevolution accelerates molecular evolution. Nature, 2010; DOI: 10.1038/nature08798

     

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    Antiviral activity of phytochemicals: a comprehensive review.

     

    Naithani R, Huma LC, Holland LE, Shukla D, McCormick DL, Mehta RG, Moriarty RM.

    Source–Department of Chemistry, University of Illinois at Chicago, Chicago-60607, USA. rajesh. naithani@gmail.com

    Numerous numbers of biologically active agents have been identified for their diverse therapeutic functions. Detailed investigations of phytochemicals for antiviral activities have assumed greater importance in the last few decades. A wide variety of active phytochemicals, including the flavonoids, terpenoids, organosulfur compounds, limonoids, lignans, sulphides, polyphenolics, coumarins, saponins, chlorophyllins, furyl compounds, alkaloids, polyines, thiophenes, proteins and peptides have been found to have therapeutic applications against different genetically and functionally diverse viruses. The antiviral mechanism of these agents may be explained on basis of their antioxidant activities, scavenging capacities, inhibiting DNA, RNA synthesis, inhibition of the viral entry, or inhibiting the viral reproduction etc. Large number candidate substances such as phytochemicals and their synthetic derivatives have been identified by a combination of in vitro and in vivo studies in different biological assays. In this article we have made attempts to extensively review and provide comprehensive description of different phyto-antiviral agents. We have examined the recent developments in the field of plant derived antiviral agents. The major advances in the field of viral interactions in various biological assays have been summarized. In addition sources of origin, major viral studies mechanistic action and phase trials of various phytoantiviral agents have been included in the review.

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    Effects of a nutrient mixture on infectious properties of the highly pathogenic strain of avian influenza virus A/H5N1.

    Deryabin PG, Lvov DK, Botikov AG, Ivanov V, Kalinovsky T, Niedzwiecki A, Rath M.

    Source—Russian Academy of Medical Sciences, D.I. Ivanovsky Research Institute on Virology, USA.

    Numerous outbreaks of avian influenza virus infection (A/H5N1) have occurred recently, infecting domestic birds, chicken and ducks. The possibility of the emergence of a new strain of influenza virus capable of causing a pandemic in humans is high and no vaccine effective against such a strain currently exists. A unique nutrient mixture (NM), containing lysine, proline, ascorbic acid, green tea extract, N-acetyl cysteine, selenium among other micro nutrients, has been shown to exert a wide range of biochemical and pharmacological effects, including an inhibitory effect on replication of influenza virus and HIV. This prompted us to investigate the potential anti-viral activity of a nutrient mixture (NM) and its components on avian influenza virus A/H5N1at viral dosages of 1.0, 0.1 and 0.01 TCID(50). Antiviral activity was studied in cultured cell lines PK, BHK-21, and Vero-E6. Virus lysing activity was determined by co-incubation of virus A/H5N1 with NM for 0-60 min, followed residual virulence titration in cultured SPEV or BHK-21 cells. NM demonstrated high antiviral activity evident even at prolonged periods after infection. NM antiviral properties were comparable to those of conventional drugs (amantadine and oseltamivir); however, NM had the advantage of affecting viral replication at the late stages of the infection process

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    Nutrient mixture containing ascorbic acid, green tea extract and amino acids suppression of influenza A virus nuclear antigen production and neuraminidase activity by mixture

    Jariwalla RJ, Roomi MW, Gangapurkar B, Kalinovsky T, Niedzwiecki A, Rath M.

    Source–Dr. Rath Research Institute, Santa Clara, CA, USA.

    Influenza, one of the oldest and most common infections, poses a serious health problem causing significant morbidity and mortality, and imposing substantial economic costs. The efficacy of current drugs is limited and improved therapies are needed. A unique nutrient mixture (NM), containing ascorbic acid, green tea extract, lysine, proline, N-acetyl cysteine, selenium among other micronutrients, has been shown to exert anti-carcinogenic and anti-atherogenic activity both in vitro and in vivo. Many of the constituents of NM have been shown to have an inhibitory effect on replication of influenza virus and HIV. This prompted us to study the effect of NM on influenza A virus multiplication in infected cells and neuraminidase activity (NA) in virus particles. Addition of NM to Vero or MDCK cells post infection resulted in dose-dependent inhibition of viral nucleoprotein (NP) production in infected cells. NM-mediated inhibition of viral NP was selective and not due to cytotoxicity towards host cells. This antiviral effect was enhanced by pretreatment of virus with the nutrient mixture. Individual components of NM, namely ascorbic acid and green tea extract, also blocked viral NP production, conferring enhanced inhibition when tested in combination. Incubation of cell-free virus with NM resulted in dose-dependent inhibition of associated NA enzyme activity. In conclusion, the nutrient mixture exerts an antiviral effect against influenza A virus by lowering viral protein production in infected cells and diminishing viral enzymatic activity in cell-free particles.

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    Recipe Green Tea and Ascorbic acid—take gun powder green tea and weight out 20 grams and pulverize it to a powder—weigh it afterwards again—then take equal parts of ascorbic acid—1:1

    Blend both together for about 5 minutes—then sift the stuff that did not break down—add to capsules and will have a strong antiviral and anti bacterial and antifungal remedy right on hand

     

     

    TOP G

    [U1]How interesting —we have a GMM= genetically modified malaria—doe that not make you go hmmmmm wonder how it got genetically enhanced to resist what once cured it !!?—Is it not interesting that we have a new species of Malaria now—apparently the old one was not killing people off fast enough so now the pharma’ have decided to make this a better pathogen
    [U2]WARNING WARNING—Understand this—Genetic Mutation–
    [U3]Interesting—if they had the money they could be relieved but no money and they are held hostage by the IMF—what a crock
    [U4] 90% kill ratio—-am I the only one seeing this is not a natural cause—weoponized malaria??

    #354
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    Chernobyl Deaths Top a Million Based on Real Evidence

    Medical records from contaminated areas speak for themselves; doctors,
    scientists and citizens bear witness to the devastating health impacts of
    radioactive fallout from nuclear accidents Dr. Mae-Wan Ho

    Official denial by nuclear lobby—The Chernobyl disaster occurred on 26 April 1986 at the Chernobyl Nuclear Power -Plant near the city of Prypiat in Ukraine, then part of the Soviet Union, and close to the administrative border with Belarus. A sudden power output surge prompted an attempt at emergency shutdown; but a more extreme spike in power output led to the rupture of a reactor vessel and a series of explosions. The graphite moderator was exposed, causing it to ignite, and the resulting fire sent a plume of highly radioactive fallout over large parts of the western Soviet Union and Europe. From 1986 to 2000, 350 400 people were evacuated and resettled from the most contaminated areas of Belarus, Russia and Ukraine. According to official post-Soviet data, about 57 % of the fallout landed in Belarus [1]. Chernobyl is widely considered to have been the worst nuclear accident in history and one of only two classified as a level 7 event on the International Nuclear Event Scale, the other being the Fukushima Daiichi nuclear meltdown in 2011 (see [2] Fukushima Nuclear Crisis, SiS 50).— From the beginning, the official nuclear safety experts were at pains to minimise the projected health impacts, as they are doing now for the Fukushima accident. The UNSCEAR (United Nations Scientific Committee on the Effects of Atomic Radiation) estimated a “global collective dose” of radiation exposure from the accident “equivalent on average to 21 additional days of world exposure to natural background radiation”. Successive studies reported by the IAEA (International Atomic Energy Agency) continued to underestimate the level of exposure and to understate health impacts other than [3] “psychosocial effects, believed to be unrelated to radiation exposure” resulting from the lack of information immediately after the accident, “the stress and trauma of compulsory relocation to less contaminated areas, the breaking of social ties and the fear that radiation exposure could cause health damage in the future.”——The number of deaths attributed to Chernobyl varies widely [1]. Thirty-one deaths are directly attributed to the accident, all among the reactor staff and emergency workers. An UNSCEAR report places the total confirmed deaths from radiation at 64 as of 2008. The Chernobyl Forum [4] founded in February 2003 at the IAEA Headquarters in Vienna with representatives from IAEA and UN agencies including UNSCEAR, WHO, the World Bank, and Belarus, Russia and Ukraine, estimates that the eventual death toll could reach 4 000 among those exposed to the highest levels of radiation (200 000 emergency workers, 115 000 evacuees and 270 000 residents of the most contaminated areas); the figure includes some 50 emergency workers who died of acute radiation syndrome, 9 children who died of thyroid cancer and an estimated total of 3950 deaths from radiation-induced cancer and leukemia. The Union of Concerned Scientists based in Washington in the United States estimates another 50 000 excess cancer cases among people living in areas outside the most contaminated, and 25 000 excess deaths. A Greenpeace report puts the figure at 200 000 or more. The Russian publication, Chernobyl, by scientists Alexey V. Yablokov, Vassily B Nesterenko, and Alexey V. Nesterenko, translated and published by the New York Academy of Sciences in 2009, concludes that among the billions of people worldwide who were exposed to radioactive contamination from the disaster, nearly a million deaths had already occurred between 1986 and 2004. Most of the deaths were in Russia, Belarus and Ukraine [5] (see Truth about Chernobyl, SiS 47). The report drew on thousands of published papers and internet and printed publications. Those publications and papers, written by leading Eastern authorities, were downplayed or ignored by the IAEA and UNSCEAR. These agencies minimised their estimates by several ploys including [6]—– Underestimating the level of radiation by averaging exposure over a large regions, such as an entire country; so high exposure doses and health statistics of the most contaminated areas are lumped together with the less and least exposed

    – Ignoring internal sources of radiation due to inhalation and ingestion of
    radioactive material from fallout

    – Using an obsolete and erroneous model of linear energy transfer due to external
    sources of ionising radiation

    – Not counting diseases and conditions other than cancers

    – Overestimating the natural background radiation; today’s ‘background’ has been greatly increased by discharges from nuclear activities including tests of
    nuclear weapons, use of depleted uranium, and uranium mining

    – Suppressing and withholding information from the public.

    Nevertheless, the devastating health impacts did not escape the notice of the hundreds of doctors, scientists and other citizens who had to bear witness to the deformities, sicknesses and deaths of exposed babies, children and adults in their care. -Diversity of health impacts and their global extent over generations to come Alexei Yablokov, distinguished academician of the Russian Academy of Sciences in Moscow, spoke at the Scientific and Citizen Forum on adioprotection – From Chernobyl to Fukushima, 11-13 May 2012 in Geneva [7]. He is adamant that the consequences of the Chernobyl disaster can be clearly demonstrated by comparing the states of people’s health in areas receiving different amounts of additional radiation following the accident, instead of one based on average effective dose calculated by the ICRP and UNSCEAR which underestimates the true levels of irradiation. For example, there is a clear difference in mortality rates between highly contaminated provinces and less contaminated provinces of Russia (see Figure 1). Yablokov is lead author of a massive report, now in its third enlarged 2011 edition [8], which has collated all the available evidence.

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    Estriol- Benefits

    Estriol, an estrogen that has virtually been ignored by the mainstream medical community, is one of the three principal estrogens produced by the body. Estriol was originally thought to have little significance due to its weak estrogenic activity when compared with estrone and estradiol. Nonetheless, research has found that its weakness may very well be its strength. –Studies suggest that when the lower-potency estrogen, estriol, is administered topically, it does not increase the risk of hormone-dependent cancers of the breast or endometrium (uterine lining).1-3 However, having weaker estrogenic effects does not mean that estriol has none of the benefits that come with more potent estrogens. Studies suggest that estriol reduces symptoms of menopause, such as hot flashes and vaginal dryness, but with a better safety profile compared with more potent estrogens.1,4,5 This makes estriol a better choice for bioidentical hormone-replacement treatment regimes. –That is not all this ‘weak’ hormone is good for! Research suggests that estriol has benefits for bone density, heart health, multiple sclerosis, and postmenopausal urinary tract health.6-12 In this article, we will review the attributes of this ‘weaker’ estrogen, and why this estrogen is currently in the news.

    F The body naturally makes three estrogen hormones—estradiol, estrone, and estriol. Since estriol possesses the weakest estrogenic effects of the three, it has been largely overlooked by the medical community.

    Many studies show that estriol offers a wealth of potential health benefits—without the dangers that sometimes accompany higher-potency estrogens and synthetic or horse-derived hormones.
    Studies suggest that estriol helps relieve menopausal symptoms while benefitting bone and urinary tract health. Estriol may also help improve cardiovascular risk factors and even shows promise in reducing the brain lesions of multiple sclerosis.
    The most reliable way to measure estriol levels is through 24-hour urine collection.
    Despite abundant evidence to the contrary, the FDA has recently claimed that estriol is not safe. You can act now to help preserve consumers’ access to bioidentical hormones such as estriol by visiting http://www.homecoalition.org.
    Fear of cancer prevents many women from restoring youthful hormone levels. When applied through the topical (transdermal) route, estriol is not associated with increased cancer risk. Other methods women can use to prevent hormone-related cancers include consuming regular amounts of vitamin D, and Bioflavonoids, Tumeric,Rosemary,Parsley,Dandelion, Hawthorn Berry, Black tea and Black Tea extracts, Celery Root, regulating meat and high-fat dairy intake.—

    Estriol and Hormone Replacement Therapy

    In addition, several studies suggest that bioidentical estrogen has less health risk when given with low doses of bioidentical progesterone.26,27— if you are on hormone-replacement therapy (HRT) and have never heard of estriol, you might be wondering why not? Before the 1970s, estriol was thought to have significance only during pregnancy we saw the beginning of hormone-replacement therapy with patented equine estrogens such as Premarin® and synthetic progestins as found in Provera®. By the 1990s, one-third of menopausal women were taking Premarin®. Research uncovered the increased incidence of breast cancer, increased risk of blood clotting, and increased cardiovascular risk associated with the use of these horse-derived and synthetic hormones (used in combination in the patented medication Prempro®).13 The medical community began to wonder if using hormones from pregnant horses was such a good idea. In an effort to find a safer alternative, many patients and practitioners began looking into ‘natural’ hormone-replacement treatment using bioidentical hormones, which are identical to those produced naturally within the body. Bioidentical-hormone replacement was pioneered in the 1980s as a treatment for menopause by Dr. Jonathan Wright in Washington state. ——-Interest in estriol increased as it was discovered that estriol was safer than horse-derived and synthetic hormones in relation to cardiovascular health and potentially cancer risk. Unfortunately, many doctors have not adopted its use, and many bioidentical hormone-replacement regimes use only estradiol, a more potent estrogen with increased associated risks.— The benefits of estriol may, in part, be explained by the mixed pro-estrogenic and anti-estrogenic effects of this interesting estrogen hormone. Scientists Melamed et al. investigated the mixture of stimulating and non-stimulating effects posed by estriol upon estrogen receptors. When estriol is given together with estradiol, the estradiol-specific stimulation to cells is decreased. This little-appreciated scientific fact helps to explain how estriol can reduce pro-carcinogenic effects of more powerful estrogens like estradiol. However, when estriol is given alone over a long period of time, it can produce a more complete pro-estrogenic effect, explaining why symptom relief is achieved when menopausal women take estriol.2 Experimental studies suggest that both estriol and tamoxifen (a synthetic anti-estrogen) have protective effects against radiation-induced cancer of the breast[U10].14— Most of the research cited in this article used oral estrogen as the route of administration. However, for enhanced safety, topical estriol would be a better choice. Several studies have shown that transdermal estrogen confers less health risk as a route of administration than oral estrogen.3,21-25 Clinical experience of many doctors over the past 20-30 years suggests that transdermal estrogen is also more effective for some women. This is largely thought to be due to the ‘first-pass effect’—meaning that orally ingested drugs are often first metabolized in the liver, before having any activity in the body. Orally ingested estrogen hormones are among these drugs that are first metabolized in the liver before exerting their effects in the body. Physicians experienced in hormone replacement often observe that women treated with oral estrogens show high levels of estrogen metabolites in 24-hour urine specimens, suggesting that most of the orally ingested hormones are being excreted.———- In a prospective study funded by the US Army and performed at the Public Health Institute, Berkeley, California, researchers compared estriol levels during pregnancy with breast cancer incidence 40 years later. Results revealed that of the 15,000 women entered in the study, those with the highest levels of estriol relative to other estrogens during pregnancy had the lowest cancer risk. In other words, as the relative level of estriol increased during pregnancy, risk of breast cancer decreased 40 years later. In fact, women with the highest level of estriol during pregnancy had 58% lower risk for breast cancer compared with women who had the lowest serum estriol levels. The authors also noted that Asian and Hispanic women had higher estriol levels compared with other racial groups. Interestingly, Asian and Hispanic women have the lowest breast cancer rates. The authors concluded, “If confirmed, these results could lead to breast cancer prevention or treatment regimens that seek to block estradiol estrogen action using estriol, similar to treatment based on the synthetic anti-estrogen tamoxifen.”15 —In another study, Takahashi et al. studied the safety of estriol treatment for Menopausal symptoms. Fifty-three women with either surgically induced or natural menopause were given 2 mg of oral estriol/day for 12 months. Endometrial and breast assessments done with endometrial biopsy and breast ultrasound, respectively, found normal results in all women. The authors concluded that over a 12-month period, “estriol appeared to be safe and effective in relieving symptoms of menopausal women.”1—In one investigation, 52 postmenopausal women were given 2 mg, 4 mg, 6 mg, or 8 mg/day of oral estriol for six months. In all patients, vasomotor symptoms of menopause (such as hot flashes) were decreased. The most improvement was experienced by women taking the highest dose of 8 mg. There were no signs of endometrial hyperplasia confirmed by endometrial biopsy over the six-month treatment period. Mammograms were obtained on six of the patients who had mammary hyperplasia at the study’s outset, and no further changes were seen.8- Although the oral route of administration of estriol appears relatively safe over the short-term, the transdermal route is preferred for long-term use. For example, Weiderpass et al. found an increased risk of endometrial atypical hyperplasia and endometrial cancer with oral use of estriol, but not with transdermal estriol over at least a five-year period. Compared with no use of estriol, those who took oral estriol for at least five years had a significantly greater risk, compared with individuals who did not take any estriol. Women using topical estriol for at least five years did not have any increased risk.

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    What You Eat Can Prevent Arsenic Overload

    ScienceDaily (June 29, 2012) — Millions of people worldwide are exposed to arsenic from contaminated water, and we are all exposed to arsenic via the food we eat. New research published in BioMed Central’s open access journal Nutrition Journal has demonstrated that people who ate more dietary vitamin B12 and animal protein had lower levels of arsenic (measured by deposition in toenails). Total dietary fat, animal fat, vegetable fat and saturated fat were also all associated with lower levels of arsenic, while omega 3 fatty acids, such as those found in fish oil, were associated with increased arsenic.—Long term exposure to high levels of arsenic is known to cause skin lesions, cancer and cardiovascular disease, and also affects fetal development. Even low concentrations of arsenic are potentially dangerous. Arsenic is found in some water supplies, but more people are exposed via their diet. Staples such as rice contain arsenic, especially the toxic inorganic forms, while fish, although high in total arsenic, contains organic forms which are thought to be less toxic.[U1]—Inside the body arsenic is methylated to aid excretion in urine but arsenic also has an affinity for keratin and can be deposited in hair and nails as they grow. Consequently levels of arsenic preserved in nails or hair can be used as a biomarker for arsenic exposure over periods of months to years.—Researchers from Dartmouth College and the Geisel School of Medicine at Dartmouth looked at the levels of arsenic in toenails of residents of New Hampshire who all use private groundwater wells as their household water source.—Results of the study showed that arsenic in nails was positively associated with both alcohol and omega 3 fatty acids, however, lower levels of arsenic were found for people who ate greater amounts of vegetable and animal fat. Prof Kathy Cottingham, who directed the study, explained, “While there may be a direct interaction between fats and arsenic preventing absorption or binding to keratin in nails, the results may simply reflect dietary preference, with people who eat a diet rich in fats not eating foods high in arsenic, such as rice.”—Joann Gruber, who led the study, noted that, “Humans can be very efficient at removing arsenic from the body. Improved methylation reduces the amount of inorganic arsenic circulating in the body. Surprisingly, we didn’t see a reduction in toenail arsenic with other dietary factors known to be necessary for arsenic methylation such as folic acid. This may be because the population we sampled had adequate amounts of these factors in their diet.”—The authors are currently working on similar studies in children, through the Children’s Environmental Health and Disease Prevention Center at Dartmouth.–Story Source-The above story is reprinted from materials provided by BioMed Central. —Journal Reference-Joann F Gruber, Margaret R Karagas, Diane Gilbert-Diamond, Pamela J Bagley, M Scot Zens, Vicki Sayarath, Tracy Punshon, J Steven Morris and Kathryn L Cottingham. Associations between toenail arsenic concentration and dietary factors in a New Hampshire population. Nutrition Journal, 2012; (in press) [link]—

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    Caffeine Boosts Power for Elderly Muscles

    Caffeine helps muscles to produce more force, new study shows.—ScienceDaily (June 29, 2012) — A new study to be presented at the Society for Experimental Biology meeting on 30th June has shown that caffeine boosts power in older muscles, suggesting the stimulant could aid elderly people to maintain their strength, reducing the incidence of falls and injuries.—For adults in their prime, caffeine helps muscles to produce more force. But as we age, our muscles naturally change and become weaker.–Sports scientists at Coventry University looked for the first time at whether these age-related changes in muscle would alter the effect of caffeine. They found that caffeine continued to enhance muscle performance in two different muscles from mice, although it was less effective in older muscles.—Jason Tallis, the study’s primary author, said: “Despite a reduced effect in the elderly, caffeine may still provide performance-enhancing benefits.”-For adults in their prime, caffeine helps muscles to produce more force. But as we age, our muscles naturally change and become weaker. So, sports scientists at Coventry University looked for the first time at whether these age-related changes in muscle would alter the effect of caffeine.–Caffeine’s effect was smallest for juvenile muscles, suggesting caffeine may not have an enhancing effect in developing muscles.–The decline in muscle strength that occurs as we age contributes to injuries and reduces quality of life. The process is not well understood, but it is clear that preserving muscle tone is key.—Tallis said: “With the importance of maintaining a physically active lifestyle to preserve health and functional capacity, the performance-enhancing benefit of caffeine could prove beneficial in the aging population.”—The researchers isolated muscles from mice ranging in age from juvenile to elderly, then tested their performance before and after caffeine treatment. They looked at two different skeletal muscles, which are the muscles we can control voluntarily. The first was the diaphragm, a core muscle used for respiration; the second was a leg muscle called the extensor digitorum longus (EDL), used for locomotion.—Story Source-The above story is reprinted from materials provided by Society for Experimental Biology, via EurekAlert!, a service of AAAS.

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    Light Weights Are Just as Good for Building Muscle, Getting Stronger, Researchers Find

    Lifting less weight more times is just as effective at building muscle as training with heavy weights, a finding by McMaster researchers that turns conventional wisdom on its head. —ScienceDaily (Apr. 30, 2012) — Lifting less weight more times is just as effective at building muscle as training with heavy weights, a finding by McMaster researchers that turns conventional wisdom on its head.—The key to muscle gain, say the researchers, is working to the point of fatigue.—“We found that loads that were quite heavy and comparatively light were equally effective at inducing muscle growth and promoting strength,” says Cam Mitchell, one of the lead authors of the study and a PhD candidate in the Department of Kinesiology.—The research, published in the Journal of Applied Physiology, challenges the widely accepted dogma that training with heavy weights — which can be lifted only six to 12 times before fatigue — is the best avenue to muscle growth.–“Many older adults can have joint problems which would prevent them training with heavy loads,” says Mitchell. “This study shows that they have the option of training with lighter and less intimidating loads and can still receive the benefits.”—For the study, a series of experiments were conducted on healthy, young male volunteers to measure how their leg muscles reacted to different forms of resistance training over a period of 10 weeks.–The researchers first determined the maximum weight each subject could lift one time in a knee extension. Each subject was assigned to a different training program for each leg.–In all, three different programs were used in combinations that required the volunteers to complete sets of as many repetitions as possible with their assigned loads — typically eight to 12 times per set at the heaviest weights and 25-30 times at the lowest weights.—The three programs used in the combinations were:

    one set at 80% of the maximum load
    three sets at 80% of the maximum
    three sets at 30% of the maximum
    After 10 weeks of training, three times per week, the heavy and light groups that lifted three sets saw significant gains in muscle volume — as measured by MRI — with no difference among the groups. Still, the group that used heavier weights for three sets developed a bit more strength.—The group that trained for a single set showed approximately half the increase in muscle size seen in both the heavy and light groups.—“The complexity of current resistance training guidelines may deter some people from resistance training and therefore from receiving the associated health benefits,” says Stuart Phillips, a professor in the Department of Kinesiology and supervisor of the study. “Our study provides evidence for a simpler paradigm, where a much broader range of loads including quite light loads can induce muscle growth, provided it is lifted to the point where it is difficult to maintain good form.”–Story Source–The above story is reprinted from materials provided by McMaster University, via Newswise. –Journal Reference—C. J. Mitchell, T. A. Churchward-Venne, D. D. W. West, N. A. Burd, L. Breen, S. K. Baker, S. M. Phillips. Resistance exercise load does not determine training-mediated hypertrophic gains in young men. Journal of Applied Physiology, 2012; DOI: 10.1152/japplphysiol.00307.2012

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    Building Muscle Without Heavy Weights

    ScienceDaily (Apr. 26, 2012) — Weight training at a lower intensity but with more repetitions may be as effective for building muscle as lifting heavy weights says a new opinion piece in Applied Physiology, Nutrition, and Metabolism.–“The perspective provided in this review highlights that other resistance protocols, beyond the often discussed high-intensity training, can be effective in stimulating a muscle building response that may translate into bigger muscles after resistance training,” says lead author Nicholas Burd. “These findings have important implications from a public health standpoint because skeletal muscle mass is a large contributor to daily energy expenditure and it assists in weight management. Additionally, skeletal muscle mass, because of its overall size, is the primary site of blood sugar disposal and thus will likely play a role in reducing the risk for development of type II diabetes.”—The authors from McMaster University conducted a series of experiments that manipulated various resistance exercise variables (e.g., intensity, volume, and muscle time under tension). They found that high-intensity muscle contractions derived from lifting heavy loads were not the only drivers of exercise-induced muscle development. In resistance-trained young men a lower workout intensity and a higher volume of repetitions of resistance exercise, performed until failure, was equally effective in stimulating muscle proteins as a heavy workout intensity at lower repetition rates. An additional benefit of the low-intensity workout is that the higher repetitions required to achieve fatigue will also be beneficial for sustaining the muscle building response for days.—Story Source—The above story is reprinted from materials provided by Canadian Science Publishing (NRC Research Press), via EurekAlert!, a service of AAAS.

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    Tannic acid inhibited norovirus binding to HBGA receptors, a study of 50 Chinese medicinal herbs.

    Bioorg Med Chem. 2012 Feb 15;20(4):1616-23

    Authors: Zhang XF, Dai YC, Zhong W, Tan M, Lv ZP, Zhou YC, Jiang X

    Abstract
    Noroviruses (NoVs) are the leading cause of viral acute gastroenteritis affecting people of all ages worldwide. The disease is difficult to control due to its widespread nature and lack of an antiviral or vaccine. NoV infection relies on the interaction of the viruses with histo-blood group antigens (HBGAs) as host receptors. Here we investigated inhibition effects of Chinese medicinal herbs against NoVs binding to HBGAs for potential antivirals against NoVs. Blocking assays was performed using the NoV protrusion (P) protein as NoV surrogate and saliva as HBGAs. Among 50 clinically effective Chinese medicinal herbs against gastroenteritis diseases, two herbs were found highly effective. Chinese Gall blocked NoV P dimer binding to type A saliva at IC(50)=5.35 μg/ml and to B saliva at IC(50)=21.7 μg/ml. Similarly, Pomegranate blocked binding of NoV P dimer to type A saliva at IC(50)=15.59 μg/ml and B saliva at IC(50)=66.67 μg/ml. Literature data on preliminary biochemistry analysis showed that tannic acid is a common composition in the extracts of the two herbs, so we speculate that it might be the effective compound and further studies using commercially available, highly purified tannic acid confirmed the tannic acid as a strong inhibitor in the binding of NoV P protein to both A and B saliva (IC(50)≈0.1 μM). In addition, we tested different forms of hydrolysable tannins with different alkyl esters, including gallic acid, ethyl gallate, lauryl gallate, octyl gallate and propyl gallate. However, none of these tannins-derivatives revealed detectable inhibiting activities. Our data suggested that tannic acid is a promising candidate antiviral against NoVs.—PMID: 22285570 [PubMed – indexed for MEDLINE]

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    Tea, nettle, wood, berries, Chinese galls. Oak wood is very rich in tannic acid. When wine is kept in oak kegs some tannic acid will migrate into the wine. High levels of tannic acid are found in some plant galls. These are formed by plants when they are infected by certain insects. These insects pierce the plant leaves and when the egg hatches out into a larva the plant produces a gall which surrounds the larva.—- Tannic acid has anti-bacterial, anti-enzymatic and astringent properties. Tannic acid has constringing action upon mucous tissues such as tongue and inside of mouth. The ingestion of tannic acid caused constipation and can be used to treat diarrhoea (in the absence of fever or inflammation). The anti-oxidant and anti-mutagenic properties of tannic acid are beneficial.— Externally, tannic acid is used to treat ulcers, toothache and wounds

     

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    Newer vitamin D tests often inaccurate, study shows-Faster, less expensive tests may overestimate vitamin D deficiency

    June 25, 2012 —

    Two new lab tests to measure blood levels of vitamin D are inaccurate more than 40% of the time, according to a new study.-Researchers say newer tests tend to overestimate the number of people who are deficient in vitamin D, a problem that could cause patients to be anxious about their health and may lead to over-treatment.[U1]-The study, which was presented at ENDO 2012, the annual meeting of the endocrine society in Houston, is adding to concerns felt in many laboratories and hospitals around the country that the results of vitamin D tests, which have become some of the most frequently ordered blood tests in medicine, are widely unreliable.-What’s more, experts say, vitamin D testing is often ordered under circumstances where there’s little solid scientific evidence to support its use.–“It’s a huge problem,” says researcher Earle W. Holmes, PhD, a pathologist at Loyola University Stritch School of Medicine, in Chicago.–Experts who were not involved in the research agree.–“The biggest problem is that they’re not even consistent,” says Ravinder J. Singh, PhD, director of the Mayo Clinic’s Endocrinology Laboratory in Rochester, Minn. “At least if they were consistent, you could say, values are half or double, compared to other tests. You can never have confidence” in the results, he tells WebMD.–The new tests, made by Abbott and Siemens, were approved by the FDA last fall.—They’re part of a wave of faster, less expensive tests designed to help laboratories keep up with a boom in demand for vitamin D testing.–Abbott took issue with the study results, pointing to a company-funded study that showed their vitamin D test delivered results that are accurate and comparable to a widely used reference method.—Siemens also defended their test, saying they are reviewing the validity of the study.

    Questions Persist About Vitamin D Testing

    It’s not the first time questions have been raised about the accuracy of vitamin D tests, however.–In 2009, Quest Diagnostics, one of the largest medical laboratories in the –At the time, industry analysts called it the largest patient recall of a laboratory test in recent memory. The company offered free retesting.–Vitamin D, the “sunshine vitamin,” plays a well-known and important role in bone health. But in recent years, a raft of research has suggested that low vitamin D may be a factor in a host of other health conditions, including depression, diabetes, cancer, heart disease, and autoimmune diseases.–As a result, doctors have increasingly ordered the test to check vitamin D levels in their patients. The number of vitamin D tests has increased six- to 10-fold over the last decade at some hospitals and laboratories. Industry analysts say the vitamin D tests are now one of the most frequently ordered lab tests in medicine.–“The rate of testing has gone up over the last five to 10 years in an almost exponential fashion,” says Naveed Sattar, MD, PhD, a professor of metabolic medicine at the University of Glasgow, in Scotland. Sattar wrote a recent editorial on vitamin D testing for The Lancet, but he was not involved in the research. Sattar says vitamin D testing has raced ahead of the science, leaving doctors in the dark about how to handle abnormal results. —“Many results are coming back in patients who appear otherwise healthy, but they appear to have low levels. And the physicians don’t know what to do, whether they should supplement or not,” Sattar says.—Sattar says there’s little evidence to suggest that supplementing vitamin D is useful, except perhaps as a treatment for bone loss. The recommended dietary allowances for vitamin D in adults up to 70 years old is 600 International Units (IU) and 800 IU for adults over 70.—While the NIH states a tolerable upper intake level of 4,000 IU, Sattar says that back in the 1950s, when vitamin D was first added to foods, the fortification process wasn’t closely monitored and some infants developed dangerously high blood levels of calcium as a result.–Beyond physical harm, however, Sattar says telling someone they are deficient in vitamin D could cause needless anxiety.—“If it were me, I’d be scratching my head. Am I doing something wrong? Should I go spend more time in the sun? Should I be eating certain foods? So that’s a hazard by itself,” he says.–Someone who looks deficient in D might be prescribed supplements and further testing, increasing costs.”I think this does need to be looked at carefully,” Sattar says.

    Study Details—Holmes and his team wanted to see how well the new tests performed compared to an older, more expensive, and more time-consuming reference method. They were hoping the hospital could switch to one of the newer tests to save money and time.–They ran blood samples from 163 patients on all three tests. The Abbott Architect test was outside an acceptable margin of error — meaning that the results were either 25% too high or too low, about 40% of the time. The Siemens Centaur2 test was either too high or too low in 48% of samples. In many cases, the newer tests showed that patients were deficient in vitamin D when the reference test indicated they were not.—The new tests use blood proteins called antibodies that bind to vitamin D. They’re faster because they look for vitamin D in samples of whole blood.–In the older, reference method, vitamin D is separated from the blood and measured. The older test can also measure two different forms of vitamin D: Vitamin D2, which is the form of the vitamin found in fortified foods and in the kind of high-potency supplements that doctors prescribe to treat patients; and Vitamin D3, the form of the vitamin that the body makes naturally after skin is exposed to sunlight. The newer test can’t distinguish between the two different types of D.—Holmes says vitamin D2 seems to confuse the tests.–He says the tests’ inability to accurately measure that form of the vitamin means that doctors can’t tell if their patients are getting any benefit from it or if they’re taking their supplements as directed.–“You can’t tell if you’re making a difference for the patients,” Holmes says.–In absolute numbers, the reference test showed 33 patients out of 163 were deficient in vitamin D, while the Abbott test showed 45 people were vitamin D deficient, and the Siemens test pointed to deficiency in 71 patients.–Current guidelines by the Institute of Medicine state a vitamin D level of at least 20 nanograms per milliliter (ng/ml) in the blood as adequate for bone health and overall health. However, other experts, including Holmes, feel that a normal level is 30 ng/ml or higher.—Manufacturers Respond–In a statement issued in response to the study, Abbott, the company that makes the Architect test, says the results of the current study depend on the use of a reference test that is “a very hands-on, labor intensive, manual procedure for which there currently is no standard protocol or calibration method. As a result, this leads to variability of results from lab to lab.”–“In current studies … as well as in recent proficiency surveys, the ARCHITECT Vitamin D test showed excellent precision and reproducibility of results from lab to lab,” the statement reads.—Siemens is checking the study’s accuracy: “Siemens Healthcare Diagnostics is committed to delivering high-quality solutions and services to our customers that enable health care professionals to accurately diagnose, treat, and monitor patients. We are closely reviewing the validity of the claims made in this report along with the design of the methods and analysis used to develop them.”—The wholesale price of the newer tests is estimated to cost around $20 to $25, although patients and insurance companies may be charged more. That’s about half the cost of the older reference test, experts said, which wholesaled for about $50 a test.–This study was presented at a medical conference. The findings should be considered preliminary, as they have not yet undergone the “peer review” process, in which outside experts scrutinize the data prior to publication in a medical journal.–SOURCES: Annual meeting of The Endocrine Society, Houston, June 23-26, 2012.Sattar, N. The Lancet, January 2012.National Institutes of Health, Office of Dietary Supplements: “Dietary Supplement Fact Sheet: Vitamin D.”Earle W. Holmes, PhD, professor of pathology and molecular pharmacology, Stritch School of Medicine, Loyola University, Chicago.Ravinder J. Singh, PhD, director, Endocrinology Laboratory, Mayo Clinic, Rochester, Minn.Naveed Sattar, MD, PhD, professor of metabolic medicine, University of Glasgow, Glasgow, Scotland, U.K.

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    Low Testosterone Appears To Increase Long-Term Risk Of Death

    ScienceDaily (June 17, 2008) — Men may not live as long if they have low testosterone, regardless of their age, according to a new study.–The new study, from Germany, adds to the scientific evidence linking deficiency of this sex hormone with increased death from all causes over time–so-called “all-cause mortality.”—The results should serve as a warning for men with low testosterone to have a healthier lifestyle, including weight control, regular exercise and a healthy diet, said lead author Robin Haring, a PhD student from Ernst-Moritz-Arndt University of Greifswald, Institute for Community Medicine.—“It is very possible that lifestyle determines levels of testosterone,” he said. —In the study, Haring and co-workers looked at death from any cause in nearly 2,000 men aged 20 to 79 years who were living in northeast Germany and who participated in the Study of Health in Pomerania (SHIP). Follow-up averaged 7 years. At the beginning of the study, 5 percent of these men had low blood testosterone levels, defined as the lower end of the normal range for young adult men. The men with low testosterone were older, more obese, and had a greater prevalence of diabetes and high blood pressure, compared with men who had higher testosterone levels, Haring said.—Men with low testosterone levels had more than 2.5 times greater risk of dying during the next 10 years compared to men with higher testosterone, the study found. This difference was not explained by age, smoking, alcohol intake, level of physical activity, or increased waist circumference (a risk factor for diabetes and heart disease), Haring said.—-In cause-specific death analyses, low testosterone predicted increased risk of death due to cardiovascular disease and cancer but not death of any other single cause.—-DPC Biermann, Bad Nauheim, Germany, provided the testosterone reagent, and Novo Nordisc provided partial funding for this analysis.—Detailed results will be presented at The Endocrine Society’s 90th Annual Meeting in San Francisco.—Story Source–The above story is reprinted from materials provided by The Endocrine Society, via EurekAlert!, a service of AAAS.

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    Sleep Loss Dramatically Lowers Testosterone in Healthy Young Men

    ScienceDaily (May 31, 2011) — Cutting back on sleep drastically reduces a healthy young man’s testosterone levels, according to a study published in the June 1 issue of the Journal of the American Medical Association (JAMA).-Eve Van Cauter, PhD, professor in medicine and director of the study, found that men who slept less than five hours a night for one week in a laboratory had significantly lower levels of testosterone than when they had a full night’s sleep. Low testosterone has a host of negative consequences for young men, and not just in sexual behavior and reproduction. It is critical in building strength and muscle mass, and bone density.-“Low testosterone levels are associated with reduced well being and vigor, which may also occur as a consequence of sleep loss” said Van Cauter.—-At least 15% of the adult working population in the US gets less than 5 hours of sleep a night, and suffers many adverse health effects because of it. This study found that skipping sleep reduces a young man’s testosterone levels by the same amount as aging 10 to 15 years. “As research progresses, low sleep duration and poor sleep quality are increasingly recognized as endocrine disruptors,” Van Cauter said. The ten young men in the study were recruited from around the University of Chicago campus. They passed a rigorous battery of tests to screen for endocrine or psychiatric disorders and sleep problems. They were an average of 24 years old, lean and in good health. For the study, they spent three nights in the laboratory sleeping for up to ten hours, and then eight nights sleeping less than five hours. Their blood was sampled every 15 to 30 minutes for 24 hours during the last day of the ten-hour sleep phase and the last day of the five-hour sleep phase. The effects of sleep loss on testosterone levels were apparent after just one week of short sleep. Five hours of sleep decreased their testosterone levels by 10% to 15%. The young men had the lowest testosterone levels in the afternoons on their sleep restricted days, between 2 pm and 10 pm. The young men also self-reported their mood and vigor levels throughout the study. They reported a decline in their sense of well-being as their blood testosterone levels declined. Their mood and vigor fell more every day as the sleep restriction part of the study progressed. Testosterone levels in men decline by 1% to 2% a year as they age. Testosterone deficiency is associated with low energy, reduced libido, poor concentration, and fatigue. The National Heart, Lung, and Blood Institute funded this study. Additional funding came from the National Institute of Diabetes and Digestive and Kidney Diseases, and the National Institutes of Health. Rachel Leproult, PhD, organized and supervised the experiment which took place in the University of Chicago Clinical Research Center.—Story Source-The above story is reprinted from materials provided by University of Chicago Medical Center, via EurekAlert!, a service of AAAS. –Journal Reference–R. Leproult, E. Van Cauter. Effect of 1 Week of Sleep Restriction on Testosterone Levels in Young Healthy Men. JAMA: The Journal of the American Medical Association, 2011; 305 (21): 2173 DOI: 10.1001/jama.2011.710

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    Declining Testosterone Levels in Men Not Part of Normal Aging
    ScienceDaily (June 23, 2012) — A new study finds that a drop in testosterone levels over time is more likely to result from a man’s behavioral and health changes than by aging. The study results will be presented June 25 at The Endocrine Society’s 94th Annual Meeting in Houston.—“Declining testosterone levels are not an inevitable part of the aging process, as many people think,” said study co-author Gary Wittert, MD, professor of medicine at the University of Adelaide in Adelaide, Australia. “Testosterone changes are largely explained by smoking behavior and changes in health status, particularly obesity and depression.”–Many older men have low levels of the sex hormone testosterone, but the cause is not known. Few population-based studies have tracked changes in testosterone levels among the same men over time, as their study did, Wittert said.

    In this study, supported by the National Health and Medical Research Council of Australia, the authors analyzed testosterone measurements in more than 1,500 men who had measurements taken at two clinic visits five years apart. All blood testosterone samples underwent testing at the same time for each time point, according to Wittert.—After the researchers excluded from the analysis any men who had abnormal lab values or who were taking medications or had medical conditions known to affect hormones, they included 1,382 men in the data analysis. Men ranged in age from 35 to 80 years, with an average age of 54.—On average, testosterone levels did not decline significantly over five years; rather, they decreased less than 1 percent each year, the authors reported. However, when the investigators analyzed the data by subgroups, they found that certain factors were linked to lower testosterone levels at five years than at the beginning of the study.—“Men who had declines in testosterone were more likely to be those who became obese, had stopped smoking or were depressed at either clinic visit,” Wittert said. “While stopping smoking may be a cause of a slight decrease in testosterone, the benefit of quitting smoking is huge.”—Past research has linked depression and low testosterone. This hormone is important for many bodily functions, including maintaining a healthy body composition, fertility and sex drive. “It is critical that doctors understand that declining testosterone levels are not a natural part of aging and that they are most likely due to health-related behaviors or health status itself,” he said.—Unmarried men in the study had greater testosterone reductions than did married men. Wittert attributed this finding to past research showing that married men tend to be healthier and happier than unmarried men. “Also, regular sexual activity tends to increase testosterone,” he explained.—The study findings were presented by Andre Araujo, PhD, who was a visiting professor at the University of Adelaide and is vice president of epidemiology at New England Research Institutes, Watertown, Mass.–Story Source-The above story is reprinted from materials provided by Endocrine Society, via Newswise.

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    World’s First GM Babies Born

    http://canadianawareness.org/2012/06/worlds-first-gm-babies-born/

    dailymail.co.uk

    The world’s first geneticallymodified humans have been created, it was revealed last night.—The disclosure that 30 healthy babies were born after a series of experiments in the United States provoked another furious debate about ethics.—So far, two of the babies have been tested and have been found to contain genes from three ‘parents’.—Fifteen of the children were born in the past three years as a result of one experimental programme at the Institute for Reproductive Medicine and Science of St Barnabas in New Jersey.–The babies were born to women who had problems conceiving. Extra genes from a female donor were inserted into their eggs before they were fertilised in an attempt to enable them to conceive.–Genetic fingerprint tests on two one-year- old children confirm that they have inherited DNA from three adults –two women and one man.—The fact that the children have inherited the extra genes and incorporated them into their ‘germline’ means that they will, in turn, be able to pass them on to their own offspring.–Altering the human germline – in effect tinkering with the very make-up of our species – is a technique shunned by the vast majority of the world’s scientists.—Geneticists fear that one day this method could be used to create new races of humans with extra, desired characteristics such as strength or high intelligence.[U2] Writing in the journal Human Reproduction, the researchers, led by fertility pioneer Professor Jacques Cohen, say that this ‘is the first case of human germline genetic modification resulting in normal healthy children’.–Some experts severely criticised the experiments. Lord Winston, of the Hammersmith Hospital in West London, told the BBC yesterday: ‘Regarding the treat-ment of the infertile, there is no evidence that this technique is worth doing . . . I am very surprised that it was even carried out at this stage. It would certainly not be allowed in Britain.’—John Smeaton, national director of the Society for the Protection of Unborn Children, said: ‘One has tremendous sympathy for couples who suffer infertility problems. But this seems to be a further illustration of the fact that the whole process of in vitro fertilisation as a means of conceiving babies leads to babies being regarded as objects on a production line.–‘It is a further and very worrying step down the wrong road for humanity.’ Professor Cohen and his colleagues diagnosed that the women were infertile because they had defects in tiny structures in their egg cells, called mitochondria.–They took eggs from donors and, using a fine needle, sucked some of the internal material – containing ‘healthy’ mitochondria – and injected it into eggs from the women wanting to conceive.-Because mitochondria contain genes, the babies resulting from the treatment have inherited DNA from both women. These genes can now be passed down the germline along the maternal line.–A spokesman for the Human Fertilisation and Embryology Authority (HFEA), which regulates ‘assisted reproduction’ technology in Britain, said that it would not license the technique here because it involved altering the germline.

    Jacques Cohen is regarded as a brilliant but controversial scientist who has pushed the boundaries of assisted reproduction technologies. He developed a technique which allows infertile men to have their own children, by injecting sperm DNA straight into the egg in the lab. Prior to this, only infertile women were able to conceive using IVF. Last year, Professor Cohen said that his expertise would allow him to clone children –a prospect treated with horror by the mainstream scientific community. ‘It would be an afternoon’s work for one of my students,’ he said, adding that he had been approached by ‘at least three’ individuals wishing to create a cloned child, but had turned down their request

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    Three coffees a day keeps dementia away

    Drinking three cups of coffee a day could reduce the risk of Alzheimer’s disease, according to a study by Florida-based researchers.

    Keeping high blood caffeine levels by drinking coffee was found to help at-risk adults over 65 to avoid the onset Alzheimer’s disease.–The study by Chuanhai Cao et al. was published online today ahead of publication in the Journal of Alzheimer’s disease.

    Coffee: main caffeine source for study participants

    The researchers monitored the cognitive status of 124 people aged between 65 and 88 displaying mild cognitive impairment (MCI), an early sign of the disease. Many participants were expected to develop Alzheimer’s within a few years.—No MCI patients with a blood caffeine level above 1,200 ng/ml developed the disease over a 2-4 year periodThe main or only caffeine source for these individuals was coffee.—Study lead author and neuroscientist Chuanhai Cao, said: “These intriguing results suggest that older adults with mild memory impairment who drink moderate levels of coffee — about 3 cups a day — will not convert to Alzheimer’s disease — or at least will experience a substantial delay before converting to Alzheimer’s,”–“The results from this study, along with our earlier studies in Alzheimer’s mice, are very consistent in indicating that moderate daily caffeine/coffee intake throughout adulthood should appreciably protect against Alzheimer’s disease later in life,” he continued.–Reduced risk, but no complete protection—The researchers claim the study is the first to provide a direct link between caffeine/coffee intake and reduced Alzheimer’s risk or delayed onset.-“We are not saying that moderate coffee consumption will completely protect people from Alzheimer’s disease,” Cao continued.—“However, we firmly believe that moderate coffee consumption can appreciably reduce your risk of Alzheimer’s or delay its onset.”—Other coffee perks–In the past year alone, coffee has been linked to a series of health benefits.—In Feburary, NutraIngredients.com reported on a study that found high consumption of coffee could reduce the risk of advanced fibrosis in those with fatty liver disease.—Another recent study found that the caffeine laden drink could reduce the risk of womb (endometrial) cancer, while other research has linked coffee to reduced diabetes risk.—-Citation–Study: ‘High Blood Caffeine Levels in MCI Linked to Lack of Progression to Dementia ,’ Journal of Alzheimer’s Disease 30 (2012) 559–572 DOI 10.3233/JAD-2012-111781-By Chuanhai Caoa, David A. Loewensteine, Xiaoyang Linc, Chi Zhangc, Li Wangc, Ranjan Duarae, Yougui Wuh, Alessandra Gianninid, Ge Baii, Jianfeng Caii, Maria Greige,, Elizabeth Schofielde, Raj Ashokc, Brent Smallj, Huntington Potterc,k and Gary W. Arendashd,

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    Prebiotics may enhance magnesium uptake from diet

    Prebiotic fibers may enhance the absorption and retention in rats, suggests new data from Purdue University with implications for bone health in postmenopausal women.—Supplementation of the diet with commercial ingredients Synergy1 (Beneo), Fruitafit HD