Scrips 2014

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    Scrips 2014

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    Acetylsalicylic acid and ascorbic acid combination improves cognition- Via antioxidant effect or increased expression of NMDARs (N-methyl-D-aspartate receptor )and nAChRs (neuronal nicotinic acetylcholine receptors)?
    Abstract
    Chronic inflammation occurs systematically in the central nervous system during ageing, it has been shown that neuroinflammation plays an important role in the pathogenesis of many neurodegenerative disorders. Aspirin, a nonselective COX inhibitor, as well as ascorbic acid, has been purported to protect cerebral tissue. We investigated the effects of subchronic aspirin and ascorbic acid usage on spatial learning, oxidative stress and expressions of NR2A, NR2B, nAChRα7, α4 and β2. Forty male rats (16–18 months) were divided into 4 groups, namely, control, aspirin-treated, ascorbic acid-treated, aspirin + ascorbic acid-treated groups. Following 10-weeks administration period, rats were trained and tested in the Morris water maze. 8-Hydroxy-2-deoxyguanosine and malondialdehyde were evaluated by ELISA and HPLC, respectively. Receptor expressions were assessed by western blotting of hippocampi. Spatial learning performance improved partially in the aspirin group, but significant improvement was seen in the aspirin + ascorbic acid group (p < 0.05). While 8-hydroxy-2-deoxyguanosine and malondialdehyde levels were significantly decreased, NR2B and nAChRα7 expressions were significantly increased in the aspirin + ascorbic acid group as compared to the control group (p < 0.05). Subchronic treatment with aspirin + ascorbic acid in aged rats was shown to enhance cognitive performance and increase the expressions of several receptors related to learning and memory process

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    Nicotinic Acetylcholine Receptors and Nicotinic Cholinergic Mechanisms of the Central Nervous System
    Subtypes of neuronal nicotinic acetylcholine receptors (nAChRs) are constructed from numerous subunit combinations that compose channel-receptor complexes with varied functional and pharmacological characteristics. Structural and functional diversity and the broad presynaptic, postsynaptic, and nonsynaptic locations of nAChRs underlie their mainly modulatory roles throughout the mammalian brain. Presynaptic and preterminal nicotinic receptors enhance neurotransmitter release, postsynaptic nAChRs contribute a small minority of fast excitatory transmission, and nonsynaptic nAChRs modulate many neurotransmitter systems by influencing neuronal excitability. Nicotinic receptors have roles in development and synaptic plasticity, and nicotinic mechanisms participate in learning, memory, and attention. Decline, disruption, or alterations of nicotinic cholinergic mechanisms contribute to dysfunctions such as epilepsy, schizophrenia, Parkinson’s disease, autism, dementia with Lewy bodies, Alzheimer’s disease, and addiction.

     

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    Prostate and Anti Aromatising—

    you will need several ingredients to make this

     

    * Rosemary-anti inflammatory—anti estrogenic-antioxidant-Liver Support

    * Grapeseed Powder-antiestrogenic-antioxidant

    * Ginger Powder and Extract-anti inflammatory— Heart ATP-Testosterone Support

    * Aspirin-anti inflammatory-anti cancer( prostate as well as others)

    * Cayenne Pepper-anti inflammatory-anti prostate cancer

    * Nettle Root-DHT Blocker and anti estrogen and Testosterone producer

    * Black Pepper-Delivery to the system due to the piperine

    * Hawthorn Leaf-Heart ATP- Anti Estrogenic

    * Siberian Ginseng– Additionally, eleutherococcus compounds bind to estrogen receptors, with no apparent effect in cell cultures

    * BHT-anti –estrogenic –antioxidant-Testosterone Support

    * Oil—Olive—Sesame Seed-Pumpkin Seed—any one will do

     

    * Take 3 oz of oil of choice—add to a glass container—–take 1 gram aspirin( 1/4tsp) 5 grams ( 1 tsp)of rosemary –siberian ginseng-hawthorn leaf –nettle root- ginger powder-Grapeseed –Cayenne and Black Pepper 1 gram ( ¼ tsp) put in glass jar with the oil—then place oil into a pot of water and allow this to boil and boil for about 15 minutes—when done take the contents and put into a blender and then blend for another 5-8 minutes—strain and add to a glass jar-Add the BHT in the end 2 grams( 2000mgs or almost half a tsp) and mix –use ¼ tsp several times daily to lower Prostate inflammation-increase Testosterone-and Minimize Aromatizing to Estrogen

     

    * You can as well use the herbals as a extract in alcohol as well to do the same thing to fuse this in the oil as a carrier and apply this either in the blending or the fusing in the oils through the boiling method

     

    * Another way is to fuse these all in honey which has as well estrogen blocking and Testosterone supporting effects—While our data shows that both honey and chrysin induce cytotoxicity and apoptosis in a prostate cancer cell line, honey is more potent. It seems that the variety of polyphenols in honey may have stronger anti-proliferative effects than chrysin alone. This is the first report on honey-induced and chrysin-induced cytotoxicity and apoptosis in human prostate cancer cells. Our data confirm that honey has cytotoxic activity against human prostate cancer cells, which is consistent with previous studies that indicate that honey and its ingredients possess antitumor and anticarcinogenic properties. The ability to induce tumor cell apoptosis is an important property in an anticancer drug that discriminates it from a toxic compound.50

     

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    Piperine reverses high fat diet-induced hepatic steatosis and insulin resistance in mice.

    Food Chem. 2013 Dec 15;141(4):3627-35

    Authors: Choi S, Choi Y, Choi Y, Kim S, Jang J, Park T

    Abstract
    This study examined the effect of piperine on hepatic steatosis and insulin resistance induced in mice by feeding a high-fat diet (HFD) for 13 weeks and elucidated potential underlying molecular mechanisms. Administration of piperine (50 mg/kg body weight) to mice with HFD-induced hepatic steatosis resulted in a significant increase in plasma adiponectin levels. Also, elevated plasma concentrations of insulin and glucose and hepatic lipid levels induced by feeding a HFD were reversed in mice when they were administered piperine. However, piperine did not reduce body weight and other biochemical markers to an extent where they became equal to the levels found in the CD-fed mice. Piperine reversed HFD-induced down-regulation of adiponecitn-AMP-activated protein kinase (AMPK) signalling molecules which play an important role in mediating lipogenesis, fatty acid oxidation and insulin signalling in the livers of mice. The expressions of lipogenic target genes were decreased, whereas the expression of carnitine palmitoyltransferase 1 (CPT1) gene involved in fatty acid oxidation was increased in the livers of the Pin50 group. Piperine significantly decreased the phosphorylation of insulin receptor substrate-1 (IRS-1) compared with the HFD-fed mice. Administration of piperine appeared to reverse preexisting HFD-induced hepatic steatosis and insulin resistance, probably by activation of adiponectin-AMPK signalling in mice.–PMID: 23993530 [PubMed – indexed for MEDLINE]

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    Oral administration of Bis(aspirinato)zinc(II) complex ameliorates hyperglycemia and metabolic syndrome-like disorders in spontaneously diabetic KK-A(y) mice: structure-activity relationship on zinc-salicylate complexes.
    Yoshikawa Y1, Adachi Y, Yasui H, Hattori M, Sakurai H.

    Author information
    Abstract
    In recent years, the number of patients suffering from diseases, such as cancer, apoplexy, osteoporosis, hypertension, and type 2 diabetes mellitus is increasing worldwide. Type 2 diabetes, a lifestyle-related disease, is recognized as a serious disease. Various types of pharmaceutics for diabetes have been used. Since the relationship between diabetes and biometals such as vanadium, copper, and zinc ions has been recognized for many years, we have been developing the anti-diabetic metal complexes as new candidates. We found that several zinc(II) (Zn) complexes exhibit glucose-lowering activity for treating type 2 diabetes. High doses of salicylates have been known to reverse hyperglycemia and hyperinsulinemia in type 2 diabetic patients. [F1]These findings strongly suggest that the combined use of Zn and salicylates achieves the synergism in treating type 2 diabetes. Because aspirin, acetyl salicylic acid, has a chelating ability, we used it as a ligand to Zn. Several Zn-salicylate complexes were prepared and their biological activities were examined in this study. The complexes with an electron-withdrawing group in the ligand exhibited higher in vitro insulinomimetic activity than those of Zn complexes with an electron-donating group in the ligand. When bis(aspirinato)Zn (Zn(asp)₂) complex was orally administered on KK-A(y) mice with hereditary type 2 diabetes, the diabetic state was improved. In addition, this complex exhibited normalizing effects on serum adiponectin level and high blood pressure in metabolic syndrome. In conclusion, Zn(asp)₂ complex is newly proposed as a potent anti-diabetic and anti-metabolic syndrome agent.

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    The pharmacology of the insulinomimetic effect of zinc complexes.
    Sakurai H1, Adachi Y.

    Author information
    Abstract
    In developing new insulinomimetic zinc(II) complexes with different coordination structures and with a blood glucose-lowering effect to treat type 2 diabetic animals, we found a potent bis(maltolato)zinc(ll) complex, Zn(mal)(2). Using the complex as the leading compound, we examined the in vitro and in vivo structure-activity relationships of Zn(mal)(2) and its related complexes in respect to the inhibition of free fatty acids (FFA) release and the enhancement of glucose uptake in isolated rat adipocytes treated with epinephrine (adrenaline), and hypoglycemic activity. Among the compounds tested, a new Zn(II) complex with allixin that was isolated from garlic, bis(allixinato)Zn(II), Zn(alx)(2), was found to exhibit the highest insulin-mimetic and hypoglycemic activities in type 2 KK-A(y) [F2]diabetic mice. On the basis of the results, Zn(alx)(2), complex was proposed to be a potent candidate for the treatment of type 2 diabetes.

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    Show of the Month May 10 2014

    Older adults- Build muscle and you’ll live longer
    One in five older Americans take medications that work against each other
    Learning and memory promoting effects of crude garlic extract
    List of Codex members
    Use of acetaminophen during pregnancy linked to ADHD in children, researchers say
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    Older adults- Build muscle and you’ll live longer
    Date:

    March 14, 2014

    Source:

    University of California – Los Angeles Health Sciences

    New UCLA research suggests that the more muscle mass older Americans have, the less likely they are to die prematurely. The findings add to the growing evidence that overall body composition — and not the widely used body mass index, or BMI — is a better predictor of all-cause mortality.–The study, published in the American Journal of Medicine, is the culmination of previous UCLA research led by Dr. Preethi Srikanthan, an assistant clinical professor in the endocrinology division at the David Geffen School of Medicine at UCLA, that found that building muscle mass is important in decreasing metabolic risk.—“As there is no gold-standard measure of body composition, several studies have addressed this question using different measurement techniques and have obtained different results,” Srikanthan said. “So many studies on the mortality impact of obesity focus on BMI. Our study indicates that clinicians need to be focusing on ways to improve body composition, rather than on BMI alone, when counseling older adults on preventative health behaviors.”—The researchers analyzed data collected by the National Health and Nutrition Examination Survey (NHANES) III, conducted between 1988 and 1994. They focused on a group of 3,659 individuals that included men who were 55 or older and women who were 65 or older at the time of the survey. The authors then determined how many of those individuals had died from natural causes based on a follow-up survey done in 2004.–The body composition of the study subjects was measured using bioelectrical impedance, which involves running an electrical current through the body. Muscle allows the current to pass more easily than fat does, due to muscle’s water content. In this way, the researchers could determine a muscle mass index — the amount of muscle relative to height — similar to a body mass index. They looked at how this muscle mass index was related to the risk of death. They found that all-cause mortality was significantly lower in the fourth quartile of muscle mass index compared with the first quartile.–“In other words, the greater your muscle mass, the lower your risk of death,” said Dr. Arun Karlamangla, an associate professor in the geriatrics division at the Geffen School and the study’s co-author. “Thus, rather than worrying about weight or body mass index, we should be trying to maximize and maintain muscle mass.”–This study does have some limitations. For instance, one cannot definitively establish a cause-and-effect relationship between muscle mass and survival using a cohort study such as NHANES III. “But we can say that muscle mass seems to be an important predictor of risk of death,” Srikanthan said. In addition, bioelectrical impedance is not the most advanced measurement technique, though the NHANES III measurements were conducted in a very rigorous fashion “and practically, this is the best situation possible in a study of this size,” she noted.

    “Despite these limitations, this study establishes the independent survival prediction ability of muscle mass as measured by bioelectrical impedance in older adults, using data from a large, nationally representative cohort,” Srikanthan and Karlamangla write, adding that BMI’s association with mortality in older adults has proven inconsistent. “We conclude that measurement of muscle mass relative to body height should be added to the toolbox of clinicians caring for older adults. Future research should determine the type and duration of exercise interventions that improve muscle mass and potentially increase survival in (healthy), older adults.”–Story Source-The above story is based on materials provided by University of California – Los Angeles Health Sciences. Note: Materials may be edited for content and length.–Journal Reference-Preethi Srikanthan, Arun S. Karlamangla. Muscle Mass Index as a Predictor of Longevity in Older-Adults. The American Journal of Medicine, 2014; DOI: 10.1016/j.amjmed.2014.02.007

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    One in five older Americans take medications that work against each other
    Date:

    March 13, 2014

    Source:

    Oregon State University

    About three out of four older Americans have multiple chronic health conditions, and more than 20 percent of them are being treated with drugs that work at odds with each other — the medication being used for one condition can actually make the other condition worse.-[F3]-This approach of treating conditions “one at a time” even if the treatments might conflict with one another is common in medicine, experts say, in part because little information exists to guide practitioners in how to consider this problem, weigh alternatives and identify different options.–One of the first studies to examine the prevalence of this issue, however, found that 22.6 percent of study participants received at least one medication that could worsen a coexisting condition. The work was done by researchers in Connecticut and Oregon, and published in PLOS One.–In cases where this “therapeutic competition” exists, the study found that it changed drug treatments in only 16 percent of the cases. The rest of the time, the competing drugs were still prescribed.–“Many physicians are aware of these concerns but there isn’t much information available on what to do about it,” said David Lee, an assistant professor in the Oregon State University/Oregon Health & Science University College of Pharmacy.–“Drugs tend to focus on one disease at a time, and most physicians treat patients the same way,” Lee said. “As a result, right now we’re probably treating too many conditions with too many medications. There may be times it’s best to just focus on the most serious health problem, rather than use a drug to treat a different condition that could make the more serious health problem even worse.”–More research in this field and more awareness of the scope of the problem are needed, the scientists said. It may be possible to make better value judgments about which health issue is of most concern, whether all the conditions should be treated, or whether this “competition” between drug treatments means one concern should go untreated. It may also be possible in some cases to identify ways to treat both conditions in ways that don’t conflict with one another.–A common issue, for example, is patients who have both coronary heart disease and chronic obstructive pulmonary disease, or COPD. Beta blockers are often prescribed to treat the heart disease, but those same drugs can cause airway resistance that worsens the COPD.–“There are several types of beta blocker that don’t cause this negative interaction, but many of the other types are still prescribed anyway,” Lee said. “It’s this type of information that would be of value in addressing these issues if it were more widely known and used.”

    The chronic conditions in which competing therapies come into play include many common health concerns — coronary artery disease, diabetes, COPD, dementia, heart failure, hypertension, high cholesterol, osteoarthritis and others.–This study was done by researchers from OSU and the Yale University School of Medicine, with 5,815 community-living adults between the years 2007-09. The lead author of the study was Dr. Mary E. Tinetti at Yale University, and it was supported by the National Institutes of Health. The analysis included a nationally representative sample of older adults, and both men and women.–The research identified some of the most common competing chronic conditions, in which medications for one condition may exacerbate the other. They included hypertension and osteoarthritis; hypertension and diabetes; hypertension and COPD; diabetes and coronary artery disease; and hypertension and depression. These issues affect millions of older Americans.–“More than 9 million older adults in the U.S. are being prescribed medications that may be causing them more harm than benefit,” said Jonathan Lorgunpai, a medical student at the Yale School of Medicine and co-author of the study. “Not only is this potentially harmful for individual patients, it is also very wasteful for our health care system.”–Direct competition between medications is just one of the concerns, the report noted. Use of multiple medications can also lead to increased numbers of falls and delirium, dizziness, fatigue and anorexia.–Story Source-The above story is based on materials provided by Oregon State University. Note: Materials may be edited for content and length.—Journal Reference-Songprod Jonathan Lorgunpai, Marianthe Grammas, David S. H. Lee, Gail McAvay, Peter Charpentier, Mary E. Tinetti. Potential Therapeutic Competition in Community-Living Older Adults in the U.S.: Use of Medications That May Adversely Affect a Coexisting Condition. PLoS ONE, 2014; 9 (2): e89447 DOI: 10.1371/journal.pone.0089447

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    Learning and memory promoting effects of crude garlic extract.

    Indian J Exp Biol. 2013 Dec;51(12):1094-100

    Authors: Mukherjee D, Banerjee S

    Abstract
    Chronic administration of aged garlic extract has been shown to prevent memory impairment in mice. Acute and chronic (21 days) effects of marketed formulation of crude garlic extract (Lasuna) were evaluated on learning and memory in mice using step down latency (SDL) by passive avoidance response and transfer latency (TL) using elevated plus maze. Scopolamine (0.4 mg/kg, ip) was used to induce amnesia in mice and piracetam (200 mg/kg, ip) served as positive control. In the acute study, Lasuna (65 mg/kg, po) partially reversed the scopolamine-induced amnesia but failed to improve learning and memory in untreated animals. Chronic administration of Lasuna (40 mg/kg/day for 21 days) significantly improved learning both in control and scopolamine induced amnesic animals. Influence of Lasuna on central cholinergic activity and its antioxidant properties were also studied by estimating the cortical acetylcholinesterase (AchE) activity and reduced glutathione (GSH) levels respectively. Chronic administration of Lasuna inhibited AchE, while increasing GSH levels. Thus the results indicate that long-term administration of crude garlic extract may improve learning and memory in mice while the underlying mechanism of action may be attributed to the anti-AchE activity and anti-oxidant property of garlic.–PMID: 24579375 [PubMed – indexed for MEDLINE]

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    Use of acetaminophen during pregnancy linked to ADHD in children, researchers say
    Source: University of California – Los Angeles

     

    “We need further research to verify these findings, but if these results reflect causal associations, then acetaminophen should no longer be considered a ‘safe’ drug for use in pregnancy,” the lead author states.-Acetaminophen, found in over-the-counter products such as Excedrin and Tylenol, provides many people with relief from headaches and sore muscles. When used appropriately, it is considered mostly harmless. Over recent decades, the drug, which has been marketed since the 1950s, has become the medication most commonly used by pregnant women for fevers and pain.-Now, a long-term study by UCLA, in collaboration with the University of Aarhus in Denmark, has raised concerns about the use of acetaminophen during pregnancy.-In a report in the current online edition of JAMA Pediatrics, researchers from the UCLA Fielding School of Public Health show that taking acetaminophen during pregnancy is associated with a higher risk in children of attention-deficity/hyperactivity disorder and hyperkinetic disorder.[F4] The data raises the question of whether the drug should be considered safe for use by pregnant women.-ADHD, one of the most common neurobehavioral disorders worldwide, is characterized by inattention, hyperactivity, increased impulsivity, and motivational and emotional dysregulation. Hyperkinetic disorder is a particularly severe form of ADHD.[F5]-“The causes of ADHD and hyperkinetic disorder are not well understood, but both environmental and genetic factors clearly contribute,” said Dr. Beate Ritz, professor and chair of the department of epidemiology at the Fielding School and one of the senior authors of the paper. “We know there has been a rapid increase in childhood neurodevelopmental disorders, including ADHD, over the past decades, and it’s likely that the rise is not solely attributable to better diagnoses or parental awareness. It’s likely there are environmental components as well.”-“That gave us the motivation to search for environmental causes that are avoidable,” said the University of Aarhus’ Dr. Jørn Olsen, another senior author and former chair of the UCLA Fielding School’s epidemiology department. “Part of the neuropathology may already be present at birth, making exposures during pregnancy and/or infancy of particular interest. Because acetaminophen is the most commonly used medication for pain and fever during pregnancy, it was something we thought we should look at.”-The UCLA researchers used the Danish National Birth Cohort, a nationwide study of pregnancies and children, to examine pregnancy complications and diseases in offspring as a function of factors operating in early life. The cohort focuses especially on the side effects of medications and infections.-The researchers studied 64,322 children and mothers who were enrolled in the Danish cohort from 1996 to 2002. Acetaminophen use during pregnancy was determined using computer-assisted telephone interviews that were conducted up to three times during pregnancy and again six months after childbirth[F6].-The researchers next followed up with parents when their children reached the age of 7. They first asked parents about any behavioral problems in their children using the Strength and Difficulties Questionnaire, a standard behavioral screening questionnaire used by scientists. It assesses five domains, including emotional symptoms, conduct problems, hyperactivity, peer relationship and social behavior in children and adolescents between the ages of 4 and 16.-In addition, they obtained diagnoses of hyperkinetic disorder among the cohort’s children (at an average age of 11) from the Danish National Hospital Registry or the Danish Psychiatric Central Registry. Last, they identified if ADHD medications, mainly Ritalin, were redeemed for the children using the Danish pharmaceutical prescription database.–More than half of all the mothers reported using acetaminophen while pregnant. The researchers found that children whose mothers used acetaminophen during pregnancy were at a 13 percent to 37 percent higher risk of later receiving a hospital diagnosis of hyperkinetic disorder, being treated with ADHD medications or having ADHD-like behaviors at age 7. The longer acetaminophen was taken — that is, into the second and third trimesters — the stronger the associations. The risks for hyperkinetic disorder/ADHD in children were elevated 50 percent or more when the mothers had used the common painkiller for more than 20 weeks in pregnancy.–“It’s known from animal data that acetaminophen is a hormone disruptor, and abnormal hormonal exposures in pregnancy may influence fetal brain development,” Ritz said.–Acetaminophen can cross the placental barrier, Ritz noted, and it is plausible that acetaminophen may interrupt fetal brain development by interfering with maternal hormones or through neurotoxicity, such as the induction of oxidative stress, which can cause the death of neurons.–“We need further research to verify these findings, but if these results reflect causal associations, then acetaminophen should no longer be considered a ‘safe’ drug for use in pregnancy,” Olsen said.–Story Source–The above story is based on materials provided by University of California – Los Angeles. The original article was written by Mark Wheeler. Note: Materials may be edited for content and length.—Journal Reference–Zeyan Liew, Beate Ritz, Cristina Rebordosa, Pei-Chen Lee, Jørn Olsen. Acetaminophen Use During Pregnancy, Behavioral Problems, and Hyperkinetic Disorders. JAMA Pediatrics, 2014; DOI: 10.1001/jamapediatrics.2013.4914

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    CODEX ADMITS IT’S NOT ABOUT HEALTH

    Codex Shoves Ractopamine Down Our Throats after Narrow Vote


    July 04, 2012

    (FAO Building – Rome, Italy)  After taking a vote by secret ballot this late morning, the Chairman of the Codex Alimentarius Commission, Mr. Sanjay Dave, announced the results of the voting on whether or not Ractopamine (a steroid-like vet drug, the residues of which remain in the slaughtered animal to then be consumed by meat-eaters) standards were adopted.  Out of 143 ballots cast, the vote was 69 for Ractopamine, 67 against Ractopamine, with 7 abstaining.  If only one vote had shifted from the “for” camp to the “against” camp, then the result would have been completely different and the Ractopamine standard would not have been adopted.— This voting was forced upon the Commission by the insistence of the United States, Costa Rica, and Brazil that the long stalemate over the adoption of a standard for Ractopamine MRLs (Maximum Residue Levels) could not be resolved through the Codex-preferred process of “consensus” but would, after all, have to be voted upon.—-The European Union (EU) and other delegations – firmly opposed to the adoption of a standard for Ractopamine that would permit WTO trade challenges against existing Ractopamine bans – challenged the need for a vote, as they knew that the United States, Canada, and others had been lobbying Codex countries since last year to support Ractopamine use throughout the World.  Nevertheless, in a late-evening Codex session held yesterday, the Commission voted to move forward on a vote, to be held today.– Numerous delegations had argued for and against the Ractopamine standard in yesterday’s session before the Chairman cut off discussion, leaving 36 country delegations and 2 INGOs (the National Health Federation and Consumers International) without any opportunity to share their views on this issue.  This decision was especially unfortunate because both NHF and CI were prepared to speak out strongly against the World Health Organization representative’s unsupported comment that the science supported the safety of Ractopamine in the food supply.  The Chairman’s abrupt decision to cut off discussion also stood in sharp contrast with that of the previous Codex Chairwoman, Karen Hulebak, who had permitted a much fuller discussion of the delegates’ views, no matter how unpopular they might have been.—The U.S. Ambassador here in Rome reportedly spent his time from 9:00 pm last night until 9:00 am this morning calling Codex delegates to lobby for their support.  In some cases – our sources report – he, or someone, instructed countries (such as Georgia) to vote the U.S. way or else.  Pro-Ractopamine lobbying had been particularly effective among African countries, with only staunch Kenya and Zimbabwe resisting the siren song of Ractopamine.—NHF president Scott Tips said this about the result, “The narrow vote reflects the absurdity of this aspect of Codex.  Here you have less than 30% of the World’s pork-consuming countries dictating standards to the other 70% plus of the World!  The European Union, Norway, Switzerland, Turkey, Russia, Kenya, and China correctly argued throughout that the science on Ractopamine was not settled, that this standard was not about health but about pushing commercial profits instead, and that Codex would be damaged by the adoption of this unhealthy standard.  In fact, that is exactly what will unfold as a result of today’s decision: Codex has lost whatever scientific credibility it ever had, even amongst those who have been its biggest supporters.  Despite especially the EU representatives’ herculean efforts – and they are truly the unsung heroines of the day – bad science and ill-health prevailed today, and the World is a worse place for it.”—-NHF predicts that today’s adoption of a standard for Ractopamine MRLs will lead to trade challenges by the United States against China and by Brazil against the European Union to crack open those consumer markets to Ractopamine-doped meat products.  The victory of the United States today in pushing the wishes of its commercial masters – and certainly not those of its citizens, most of whom oppose Ractopamine-doped foods – may very well backfire on that country and its minions as a chain reaction of events unfold, the full scope of which no one here yet knows.

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    Vaccine-Induced Tissue Scurvy Globally Misdiagnosed as Child Abuse

    The father of the child in our published photo was jailed for life for child abuse. Many of you looking at the terrible injuries on this small child will immediately assume, as did the doctors who examined him, that he was viciously attacked and it was right to jail his father.–However, what if I told you that it was later proven that this child had in fact been suffering from Kawasaki disease, otherwise known as tissue scurvy, and that his father was innocent?–Well, that is exactly what happened. Due to the wonderful work of Dr. Michael Innis and a team of experts brought in by the family to help, he is well and happy and back home with his family after his father was released from jail as an innocent man——What Research Tells Us About Tissue Scurvy—Studies have revealed that parents and caregivers worldwide are being falsely accused of child abuse when children develop the autoimmune disease, tissue scurvy, after vaccination.–In a recent paper by Dr. Michael Innis, he stated that“Some doctors are unaware of the pathophysiological processes of autoimmunity, haemostasis and osteogenesis and are misdiagnosing vaccine induced tissue scurvy, absence of vitamin C within the cell, as non-accidental injury.”—His paper, Autoimmune Tissue Scurvy Misdiagnosed as Child Abuse, outlined three cases of children suffering from symptoms mimicking those of shaken baby syndrome (SBS) whose parents were subsequently accused of child abuse.—However, it was later discovered that all three parents were innocent and far from being abused, their children had been suffering from the autoimmune disease known as tissue scurvy.—Dr. Innis wrote“Tissue scurvy, unlike the “seafarer scurvy” of yesteryear, is a condition in which vitamin C is abundant in the blood but is unable to enter the cell because of a lack of insulin which is required to transfer the vitamin C into the cell.”—He stated that“The many faces of tissue scurvy in childhood include sudden infant death syndrome, alleged non-accidental injury, shaken baby syndrome, abusive head trauma, inflicted brain injury, Reye’s syndrome, Kawasaki disease, anaphylaxis and diabetes type I.—All have one feature in common – hyperglycemia, the signature of insulin deficiency resulting from vaccines, and other forms of antigenic stress which damage the beta cells of the islets of Langerhans resulting in hypoinsulinemia and tissue scurvy.” [1]—-Dr. Innis firmly believes that doctors are misdiagnosing vaccine-induced tissue scurvy (an absence of vitamin C within the cell) as a non-accidental injury.—In his impressive paper, published last year by the Science Publishing Group, he wrote–“In all the cases in which appropriate histories and tests were done there was evidence that the doctors either misinterpreted the laboratory evidence or they were unaware of the significance of abnormal tests suggesting tissue scurvy as the cause.”—

    The father of this child was accused of abuse and put in jail.—-A Second Paper By Dr. Innis Reveals Similar Findings—-In a second paper on the subject, Dr. Michael Innis stated that it is postulated that Kawasaki disease is tissue scurvy, a disease often found in children under the age five. Children suffering from the condition usually present with a fever, redness of the eyes, blotchy red skin lesions, changes in the mouth and cracked lips, swelling of the hands and feet and lymph node enlargement in the neck.—Describing the case featured in our lead photo in detail, Dr. Innis stated—-“A child presenting with the signs and symptoms of Kawasaki disease was diagnosed as suffering from non-accidental injuries. Investigations were carried out for evidence of insulin deficiency and liver dysfunction.—It was found that there was evidence of hyperglycemia, implying insulin deficiency and the liver function tests were abnormal.”—He continued by stating that“Kawasaki disease is an autoimmune disorder following antigenic stimulation in a genetically susceptible child which causes insulin deficiency and failure of the cellular uptake of vitamin C, tissue scurvy, and can be mistaken for child abuse. Vaccines are a proven cause of hyperglycemia in children and may be a cause of Kawasaki disease.”—Throughout his description of the case, he demonstrated how doctors missed vital signs, preferring to jump to the conclusion that the child had been severely abused by the carer, instead of investigating the truth.—In many ways, it is easy to see why this occurred, as the photos accompanying the report are graphic, and to an untrained eye they would immediately raise suspicion. However, the professionals examining the child in question were all ‘highly qualified,’ and should have carried out a full battery of tests before jumping to the conclusion that the child had been abused.—Showing the blood test results in detail, Dr. Innis explained—The alacrity with which the admitting doctor declared “trauma level I” colored subsequent clinical and investigative procedures. The possibility of Kawasaki disease was never raised and the ANCA and AECA tests which are sometimes positive in this type of vasculitis were never done. However the presence of hyperglycemia is clear evidence of insulin deficiency provoking the onset of tissue scurvy. The coronary vessels and myocardium should have been thoroughly investigated, as they are a major cause of death in Kawasaki disease.” [2]—Another Specialist’s Perspective on Tissue Scurvy—Dr. Innis is not the only professional who has linked Kawasaki disease to vaccinations. In 2000, psychologist Lisa Blakemore-Brown wrote Reweaving the Autistic Tapestry, a book on autism and interweaving disorders.–One of the chapters centered on a little girl she had renamed Lorelei. Lorelei had reacted extremely badly to the pertussis vaccination and this adverse reaction had been fully documented by the National Health Service (NHS) in the child’s hospital notes. Lorelei was diagnosed with Asperger’s syndrome and Kawasaki disease.–In 2001, Ms. Blakemore-Brown highlighted the case in a rapid response on the British Medical Journal’s website, in response to an article titled A Finnish Study Confirms Safety of MMR. [3] Amazingly, her response was published with a footnote stating that the editor had checked her facts and that the parents of the child had given their permission for the piece to be published.—Ms. Blakemore-Brown wrote—“In one of my cases of very obvious and indisputable reaction to pertussis vaccine the child in question has been found to have Kawasaki disease, her own immune system attacking itself. She presents as Asperger. There is no autism in the family but the baby had allergies prior to the vaccine. It is scientific examination of cases like this which will enable us to ultimately put measures in place to reassure the public.” [3]—-The First Links Discovered As Far Back As 1962—The late Dr. Archie Kalokerinos was one of the first professionals to link vaccinations to scurvy. He first noticed there was a problem while he was working with Aborigine children in Australia in 1962.—While there, he noticed that there was an extremely high death rate among children recently vaccinated. After rejecting the usual explanations, his research led him to the conclusion that the infants were suffering from a severe lack of vitamin C, or scurvy.—Dr. Kalokerinos went on to speak about his experiences worldwide and included his research in many books and papers on the subject. However, when he mentioned his fears to the government, instead of investigating the problem as he had expected, he was met with extreme hostility.—In an interview documented in the International Vaccine Newsletter – June 1995, he stated–“At first it was just a simple clinical observation. I observed that many infants, after they received routine vaccines like tetanus, diptheria, polio, whooping cough or whatever, became ill. Some became extremely ill, and in fact some died. It was an observation, it was not a theory. So my first reaction was to look at the reasons why this happened. Of course I found it was more likely to happen in infants who were ill at the time of receiving a vaccine, or infants who had been ill recently, or infants who were incubating an infection. Of course in the early stages of incubation there is no way whatsoever that anyone can detect the disease. They turn up later on. Furthermore, some of the reactions to the vaccines were not those that were listed in the standard literature. They were very strange reactions indeed.—A third observation was that with some of these reactions which normally resulted in death, I found that I could reverse them by giving large amounts of vitamin C intramuscularly or intravenously.”—Extremely concerned by his observations, he tried to alert the government to what was happening. However, what happened next shocked him. He explained–“One would have expected, of course, that the authorities would take an interest in these observations that resulted in a dramatic drop in the death rate of infants in the area under my control, a very dramatic drop. But instead of taking an interest their reaction was one of extreme hostility. This forced me to look into the question of vaccination further, and the further I looked into it, the more shocked I became. I found that the whole vaccine business was indeed a gigantic hoaxMost doctors are convinced that they are useful, but if you look at the proper statistics and study the instance of these diseases you will realize that this is not so.” [4]–Strong words, I am sure you will agree, especially as he concluded the interview by stating that“My final conclusion after forty years or more in this business is that the unofficial policy of the World Health Organization and the unofficial policy of Save the Children Fund and almost all those organizations is one of murder and genocide.—They want to make it appear as if they are saving these kids, but in actual fact they don’t. I am talking of those at the very topBeneath that level is another level of doctors and health workers, like myself, who don’t really understand what they are doing.”Like Dr. Innis, over the years his conclusions have led him to believe that the trend of parents being falsely accused of shaken baby syndrome is linked to scurvy, and in his final book titled Shaken Baby Syndrome: An Abusive Diagnosis, he wrote:—“After studying more than 50 SBS cases, I have yet to find one where a detailed analysis of the complete individual or family history, or a proper evaluation of all the necessary coagulation/bleeding factors was undertaken. Often, a diagnosis of trauma due to shaking is made at an early stage and any further investigation is considered unnecessary.—It has been known for many years that retinal hemorrhages, subdural hemorrhages and hemorrhages elsewhere can occur in cases of scurvy.” [5]—Throughout his book, he identified vaccination as the main cause of scurvy in young children today.—Conclusion—In trying to help falsely accused parents worldwide, I am currently aware of at least seven falsely accused parents whose children became ill after they received multiple vaccinations. In four of these cases, tests revealed that, far from being abused, the children had been suffering from the autoimmune disease tissue scurvy.—Why are governments around the world burying their heads in the sand and refusing point-blank to investigate this atrocity? INNOCENT parents are being locked up on a daily basis, accused of the most horrendous crimes, and it seems as if no one actually cares.–The evidence speaks for itself: not only are vaccinations harming our children, but that harm is being covered up by blaming innocent parents of abuse.-I would like to extend my gratitude to the wonderful and continuing work of Dr. Michael Innis, without whom many innocent parents would be still be in jail today.

    References—-1. http://www.sciencepublishinggroup.com/journal/paperinfo.aspx?journalid=151&doi=10.11648/j.cmr.20130206.17
    2. http://www.sciencepublishinggroup.com/pdf/10.11648.j.ajim.20130102.13.pdf
    3. http://www.bmj.com/content/322/7279/130.3?tab=responses
    Scroll down to read her response.
    4. http://www.vaccinationinformationnetwork.com/an-interview-with-dr-archie-kalokerinos-md/
    5. http://www.vaccinationcouncil.org/2012/08/14/dr-kalokerinos-last-book/
    Page 11 – Link to PDF only

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    Homemade mosquito trap

    /worth a try to find out so passing this along

    Apr 22, 2014

    WITH WARMER WEATHER COMES MOSQUITOS! WITH SUMMER APPROACHING I THOUGHT I’D SHARE THIS AGAIN

    WOW– I am making 100 of these!!!

    Have you noticed the Mosquitos are already out! Here is a homemade trap to help keep you and the kiddos from being a blood donor!!!

    HOMEMADE MOSQUITO TRAP:
    Items needed:
    1 cup of water
    1/4 cup of brown sugar
    1 gram of yeast
    1 2-liter bottle

    HOW:
    1. Cut the plastic bottle in half.
    2. Mix brown sugar with hot water. Let cool. When cold, pour in the bottom half of the bottle.
    3. Add the yeast. No need to mix. It creates carbon dioxide, which attracts mosquitoes.
    4. Place the funnel part, upside down, into the other half of the bottle, taping them together if desired.
    5. Wrap the bottle with something black, leaving the top uncovered, and place it outside in an area away from your normal gathering area. (Mosquitoes are also drawn to the color black.)

    Change the solution every 2 weeks for continuous control.

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    Organic Farming Testing

     I worked for five years as a USDA-contract organic inspector after growing up on an organic grain farm in Saskatchewan. I had the pleasure of inspecting over 500 organic farms and processors, but I began questioning this career path when I realized the organic movement was becoming little more than a political movement, relying increasingly on imports, and aimed at taking farming back in time. I still support the principles of organic production. But when the organic movement went anti-GMO, it was time for a major rethink—The organic movement could be perfectly valid once again, but only if it remains a niche production-system, and, crucially, if the captains of the organic movement drop their knee-jerk opposition to technology and start proving that organic food is being produced without synthetic pesticides and fertilizers. How? Simple, through across-the-board, once-annual field testing.  Most people are shocked to learn that organic crops are not tested, and that exhaustive record-keeping and record-checking by for-profit agents of the USDA is what qualifies products for the lucrative ‘USDA Organic’ logo. There are plans afoot under the USDA National Organic Program (NOP) to spot-testing organic operations, but only one-time every 20 years, and only on end-product, long after substances prohibited in organic production have dissipated. When the organic movement went anti-GMO, it was time for a major rethink It was this slovenly attitude that opened the floodgates to cheap, USDA-certified organic raw ingredients imported from countries like China, Mexico and Argentina, to the point where there is now one certified-organic food processor in America for every two certified-organic farmers. So much for saving American organic family farms –By applying loopholes in the law, these processors can, for instance, add water to USDA certified-organic apple-juice concentrate from abroad, put it in a carton and call it ‘Product of the U.S.A.’ even though the apples were grown, processed and certified under the USDA National Organic Program (NOP) by foreigners in a foreign land. When trying to shut me up failed, my former colleagues turned to attacking my integrity, charging that I work for Monsanto, that I’m an ‘extreme right-winger,’ that I made up my credentials as an organic inspector, and that I plan to line my pockets by starting an organic testing lab, none of which is true. Finally, I was threatened, and have repeatedly been refused membership in my former professional organization, the International Organic Inspectors Association, a body on which I was once on the executive, and for which I organized the first ever ‘Organic Testing’ training seminar–GMOs should become part of The organic movement That’s what I got for urging those above me to test organic crops and livestock to ensure they’re safe and genuine. How silly of me. Then came something completely unforgivable in the minds of organic activists: I realized that modern, science-based farming presents no threat whatsoever to organic farming, whether we’re talking about the use of synthetic fertilizers or pesticides on neighboring conventional farms, or the new science of genetic engineering. I came to realize, as President Clinton did, that genetically-modified organisms (GMOs) should someday become part of the organic movement, at least on a case-by-case basis. GMO Bt crops are the best example. Currently, organic farmers spray Bacillus thurengiensis, a microbial pesticide, over their fields, inhaling it as they go, and watching as it drifts into non-target areas affecting non-target organisms. So, what scientists did over at that ‘evil’ company called Monsanto was they spliced Bt genes into corn, soy and cotton, thereby eliminating the need to spray, and ensuring that only insects that actually consume a farmer’s crop will be affected. And for believing this was a step forward in modern, environmentally-conscious farming, my former colleagues decided it was necessary to launch a full-frontal assault against my reputation Since when did Mother Nature rely on chemical mutagenesis? Meanwhile, organic farmers use seeds that are produced with nuclear and chemical mutagenesis– haphazard processes that are unpredictable and distinctly UN-natural. They also make liberal use of inorganic, environmentally-persistent substances such as haphazard processes that are unpredictable and distinctly UN-natural copper sulfate which have no corollary in nature. These are just two examples that do not fit the anti-GMO mantra used by longtime GMOs are novel patented organisms that have never before been part of nature or part of the human diet Stop and think… just how much copper sulfate do you think your ancestors used to consume in their diet? And when’s the last time Mother Nature relied on chemical mutagenesis? Not a single organic crop has ever been de-certified as a result of coming into contact with GMO material in any way, including cross-pollination Once done attacking GMOs here at home, activists like Riddle trot off to foreign lands like Iran– in order to help the Iranians develop their organic agriculture industry But how about helping American organic farmers instead? Remember, fully one-third of all domestic USDA certified-organic operations are processors , not farmers, which is like having a doctor for every two patients in a town. Clearly that doctor would need to treat outside patients to remain profitable, which is fine, until he starts ignoring his local patients to better serve the outside ones Currently, organic farmers spray Bacillus thurengiensis, a microbial pesticide, over their fields, inhaling it as they go, and watching as it drifts into non-target areas affecting non-target organisms. .. Monsanto spliced Bt genes into corn, soy and cotton, thereby eliminating the need to spray, and ensuring that only insects that actually consume a farmer’s crop will be affected. Meanwhile, there is in point-of-fact no such thing as contamination of an organic crop by GMOs. According to the very rules for organic production that organic stakeholders like Riddle wrote, organic farmers are not allowed to make use of GMOs, the same as they’re not allowed to make use of the herbicide Roundup. But not a single organic crop has ever been de-certified as a result of an organic crop coming into contact with GMO material in any way, including cross-pollination. This is not to say some activist farmers have not tried claiming their organic crops were threatened by the mere presence of GMOs. But, in all such cases, these farmers ended up plowing their crops under before any testing could be done, and as such appear not to have followed the rules of organic production in the first place. It’s time for all the organic fear-mongering to end.  ***********************************************************************

    Gardasil Contaminant Confirmed By Independent Lab

    In September 2011, SaneVax Inc. informed the FDA that despite all Merck’s statements claiming Gardasil contained ‘no viral DNA,’ Dr. Sin Hang Lee had discovered there were indeed fragments of HPV-11HPV-16 and HPV-18 L1 DNA firmly attached to Merck’s proprietary aluminum adjuvant in 100% of the samples his laboratory tested.

    The FDA was quick to confirm that Gardasil did indeed contain residual HPV L1 DNA fragments, but that these fragments ‘posed no health risk.’

    By 2012, Dr. Lee had discovered that these HPV DNA fragments were not only bound to Merck’s proprietary aluminum adjuvant, but they had also adopted a non-B conformation, thereby creating a novel (new) chemical compound of unknown toxicity.

    Non-B DNA conformations are known to be associated with genetic mutations connected to over 70 serious diseases in human beings including polycystic kidney disease, adrenoleukodystrophy, follicular lymphomas, and spermatogenic failure, just to name a few.

    Instead of investigating any potential problems which could be caused by injections of this new chemical compound, HPV vaccine proponents and government health officials chose to try and minimize the impact Dr. Lee’s discovery might make on HPV vaccination programs around the globe. Rather than conducting legitimate studies to determine the extent of potential risks, they chose to attack the messenger.

    Helen Petousis-Harris PhD, the Director of Immunisation Research and Vaccinology Immunisation Advisory Centre at The University of Auckland, provided a prime example of these tactics in a presentation she gave at a public hearing on HPV vaccine safety in February 2014.

    Following are two of the ‘concerns’ regarding Dr. Lee’s research she mentioned during this presentation:

    • The tests used were over sensitive, increasing the risk of amplifying irrelevant (junk) DNA
    • No one else has replicated his findings

    Both of these ‘concerns’ were put to rest via data presented by Laurent Bélec at the 9th International Congress on Autoimmunity on March 26-30, 2014 in Nice, France.

    Confirmation of the Creation of a Novel Molecule in Gardasil

    Confirmatory detection of human papillomavirus (HPV) L1 gene DNA sequences in the quadrivalent HPV vaccine Gaardasil® based on virus-like particles production by recombinant expression of major capsid antigen L1 yeast

    Hélène Péré, Claire Fayard, Laurent Bélec
    Assistance Publique – Hôpitaux de Paris, Laboratoire de Virologie, Hôpital Européen Georges Pompidou, Paris, and Faculté de Médecine Paris Descartes, Université Paris Descartes (
    Paris V), Sorbonne Paris Cité, Paris, France

     *********************************************************************

    Cold winter may have killed off 30% of honeybees

    The harsh winter, which set cold records in many regions, has been a trial for many Canadians. For some bugs, though, the fluctuating cold temperatures could be even more challenging, if not downright fatal.–Some entomologists are particularly concerned about how honeybees and butterflies are handling the cold weather.-“More than 30 per cent of the honeybees could be killed off,” says Evelyn Boychuk, an animal biologist and specialist in insect cold tolerance.-Honeybees live in hives throughout the winter, unlike other insects, which either migrate or avoid cold by burrowing in soil or moving indoors.-The bees rely on nectar and pollen from flowers for fuel, but the prolonged cold weather has also affected the spring growing season. If there are no flowers for honeybees to feed on when they come out of hibernation, the insects could starve.-According to Boychuk, the lack of sustenance could also affect butterflies, as they spend the winter as larva, surviving without food all winter and during metamorphosis in the spring.-Boychuk says for “sensitive” species such as these, factors like when hibernation begins, how long they hibernate and when they come out can influence their survival rates.-John Klymko, director of the Maritime Butterfly Atlas, says although they don’t have records yet, he suspects there won’t be a noticeable decline in butterfly populations this spring.-He says butterflies are a resilient species and will most likely have fared well through the winter.-Even so, he says extreme winters in the future could affect how many insects “overwinter,” a term entomologists use to describe how an insect survives the snowy season.-“In general, if habitats become degraded by global climate change, some species will become less resilient or more vulnerable to any sort of hardship,” says Klymko.-Although bees might be having a rough go of it this spring, the news for Canadian cottagers is that mosquitoes and blackflies will most likely be as plentiful as always.-According to entomologists, these insects are well adapted to the Canadian weather and can survive in the cold.-Boychuk says mosquitoes and blackflies probably spend the winter under blankets of snow, where temperatures stay around zero degrees Celsius, so they don’t feel the cold the way we do.-“A lot of snow cover insulates those habitats that insects like to use in the winter, like soil and leaf litter and things,” says Brent Sinclair, an associate professor at the University of Western Ontario who researches cold tolerance in insects.-However, in areas with extreme temperatures but little snow cover, there can be what’s called “cold frost penetration.” Sinclair says this phenomenon occurs when frost travels deeper into the soil as a result of cold temperatures occurring without snowfall to insulate the soil.-Cold frost penetration could expose hibernating insects to lower temperatures, and as a result lead to a decline in insect populations, says Sinclair.-He points out that the colder-than-usual temperatures may actually benefit insects such as mosquitoes and blackflies in the reproduction department.-During hibernation, a mosquito’s metabolic system slows down, allowing it to conserve energy. A longer winter means more stored energy, which could lead to greater reproductive activity in the spring and thus a spike in their numbers.-“I could argue that some of these species will actually do better, that they’ll actually be able to produce more eggs for babies early in the season, which could lead to an earlier bug season,” says Sinclair.-Even so, it’s hard for entomologists to predict what happens to each species over the course of the winter.-“Each insect responds to cold temperatures in different ways,” says Steve Marshall, entomologist from the University of Guelph.-“Some have antifreeze like we have in our cars that stops them from freezing. Some of them avoid cold temperatures by going down into the soil and into tree trunks. Some leave town altogether. Some just die and repopulate the area from southern locations every year,” says Marshall.-“It’s very difficult to tell.”

    ***********************************************************************

    How to Make Gel Fuel with Calcium Acetate

     How to Make Gel Fuel with Calcium Acetate If you’d like to use calcium acetate, which is actually the more preferred method, you can either buy it or make it yourself. Making calcium acetate at home: You’ll need crushed chalk (calcium carbonate) and white vinegar (acetic acid). Combine 4 parts vinegar to 1 part chalk and the result will be carbon dioxide, which will evaporate, and calcium acetate and water, both of which will remain. This process smells like rotten eggs, just so you know. You’ll be left with a solid on the bottom and a liquid on the top. It’s the solid that you want, though you’ll need some of the liquid to make the gel. You’ll need to evaporate 1/2-2/3 of the water out of the solution. You can do it by placing the solution in the oven for a few hours, sitting it in the sun, or carefully evaporating it on “low” on the stove top. You can also strain it using a cheesecloth or coffee filter. Making the gel fuel: Combine 9 parts isopropyl alcohol and 1 part calcium acetate. Stir together and it will instantly begin to gel. Put it in the empty soup cans as described above. Add some water in if you’re using solid calcium acetate that you bought. The ratio, regardless of whether you’re making your own or adding water to store-bought, is about 1 part water to 3 parts calcium acetate. The Math Made Easy We hate translating “parts” to actual measurements so we’re going to put this in cooking language for you. To get the proper ratio of calcium acetate to water, use 3/4 cup calcium acetate and 1/4 cup water. Now, since it’s only 1 part of this mix to 9 parts isopropyl alcohol. There are 16 cups in a gallon so if you use 1 gallon of isopropyl alcohol, you need to add 1 3/4 cup + 1 teaspoon of the calcium aceate/water mixture to get the right ratio. After that, if the gel is too thick for your liking, just add a bit more isopropyl alcohol until you’re satisfied. Making it Pretty Many people like to burn fuel gel in the fireplace or in pretty pots for ambiance. If you’d like to do that, you can jazz up the fuel by making it crackle when it burns, so that it sounds like wood burning. To add this effect, add 2 tablespoons of cooking oil to each gallon of alcohol (1 teaspoon per 12 ounces of fuel gel). If you’d like to get even fancier and make it smell good, pick up your favorite scented oil from the local craft store and use that in place of part (or all) of the cooking oil. We’ve talked about the importance of morale in various articles throughout this site, and we stand by that idea. If you’re making gel fuel at home for survival, making it sound homey or smell good won’t make it less functional but it may make you feel good when things look bleak. Words of Warning The measurements given here are just a jumping off point. If you want to make a huge batch, just follow the ratios. A word of warning though; just because gel fuels won’t spill like liquid fuels will, make no mistake that they WILL burn you. The fire is hot and it burns for a long time, so if you get the lit gel on you, it’s not going to be pretty. Take all of the same precautions with it that you would with any other highly flammable liquid. Label it well, store it away from heat and sunlight, and keep it out of the reach of children and pets. Now you know how to make gel fuel at home for your stockpile. You can store it for practically forever as long as you keep it covered, but you still need to be cautious. We like to seal ours in plastic zip bags to keep the moisture out, but that’s just our preference. If you’ve made gel fuel, tell us about your experience in the comments section below.

    Read more at: http://www.survivopedia.com/diygelful/

    ****************************************************************************

    NASA Proposes Spraying Stratospheric Aerosols Into Earth’s Atmosphere

    It’s really amazing how many people are waking up to the fact that “chemtrails” are different from “con-trails.” What was once considered a conspiracy to many is now a fact, chemicals are constantly sprayed into our atmosphere and have been for quite some time now.-Not long ago, NASA personnel gave a lecture (that was also streamed live) at their Jet Propulsion Laboratory at the California Institute of Technology. It was a series of talks by scientists and engineers exploring the topic of Geoengineering and Climate Intervention. (1)–Some of you might be thinking, “Geoengineering, what is that?” Geoengineering encompasses strategies to combat and reduce the effects of global warming and climate change. It’s the deliberate and large-scale intervention in the Earth’s climatic system, and one of these methods, as illustrated in the lecture, is called Solar Radiation Management (SRM) by spraying stratospheric aerosols into the atmosphere(1) The lecture outlines how SRM would require the equivalent of airplanes spraying aerosols into our atmosphere for decades. You can see this at approximately the 32 minute mark. It seems it’s already happening . –These programs are also considering spraying Aluminum into the atmosphere (if not already doing it).—“There might be some good reasons to think about aluminum. Aluminum has four  times the volumetric rate for small particles as does sulphur. That means you have roughly 16 times less the coagulation rate, and that’s the thing that really drives removal.” – David Keith, Canadian Environmental Scientists, Professor of Applied Physics at Gordon McKay, Professor of Public policy, Harvard University, President of Carbon Engineering. (2)–The idea of spraying aluminum into our atmosphere goes way back, patents exist that clearly demonstrate the consideration of such materials that include the oxides of metals which have high emissivity. These include harmful substances like aluminum oxide and thorium oxide. A great patent example is one from the Hughes Aircraft Company that dates all the way back to 1990, that’s over twenty years ago. You can take a look at it here.—“We do stuff in the stratosphere all the time off-course, so it’s not as though the stratosphere is absolutely pristine. But you don’t want to have people going off and doing things that involve large radioactive forgings, or programs that go on for extended periods or for that matter provide lots of reactive surfaces that could result in significant ozone destruction.” – M. Granger Morgan, Carnegie Mellon University, University and Lord Chair Professor of Engineering and Public Policy, National Academy of Sciences Member (2)Did you know that “they” do stuff in the atmosphere all the time? Is he referring to the Department of Defense? These programs are indeed backed by agencies like the CIA and NASA, they support the National Academy of Sciences with regards to geoengineering projects, and still do till this day. (3)(4)Why are Defense Intelligence Agencies in control? Is this a national security issue? If so, that means happenings with regards to geoengineering might remain classified.–Below is a visual I used from a previous article to give you a good idea about SRM.-If you are a constant observer of the skies, as I am, it’s not hard to see that something is already going on. This has been voiced by various individuals from all over the world. For example, Rosalind Peterson, president and Co-Founder of the Agriculture Defense Coalition (ADC), and x United States Department of Agriculture (USDA) employee stated at a 2007 United Nations hearing on global warming that:—“One of the things that’s affected by climate change is agriculture, but some of what we are seeing  is man made, but man made in a different way than what you may guess. Weather modification programs, experimental ones done by private companies, the US government, are underway and there are more than 50 operations underway across the United States. All of these impact agriculture because they change the micro-climates needed for agriculture to survive. None of these programs are done with oversight. International corporations are modifying our weather all the time, and modifying it in ways that cover thousands and thousands of square miles. Most of it is chemically altered, so what happens is that we are putting ground based chemicals that are shot into the air that change and modify our weather.”—You can read more, and view that full hearing here.—A former premier of British Columbia felt so strong about the issue that he sent out a letter across Canada to multiple politicians voicing his concern. You can read more about that here.  Neurosurgeon Russel L. Blaylock made some noise about health concerns as a result of nanoaluminum spraying, you can read about that here.–Anybody who looks out their window on a bright day and watches these trails will notice them spread out and expand until the sky is covered with them. Contrails don’t do that.—There is plenty of evidence to suggest that these geonengineering techniques have already begun, and were initiated a long time ago.-As far as global warming goes, that’s another controversial topic. There is no doubt climate change is occurring, but why and how is still not well understood. –There are better ways to operate here on planet Earth, ways that are more harmonious with the planet. One example is Free Energy, and another is Solar.

    #784
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    Lecithin as a therapeutic agent in ulcerative colitis.

    Dig Dis. 2013;31(3-4):388-90

    Authors: Stremmel W, Gauss A

    Abstract
    Lecithin [phosphatidylcholine (PC)] was shown to account for more than 70% of total phospholipids within the intestinal mucus layer. It is arranged in lamellar membranes (surfactant-like particles) and establishes a hydrophobic barrier preventing invasion of the colonic commensal microbiotaIn ulcerative colitis (UC), the mucus PC content was demonstrated to be reduced by about 70%, irrespective of the presence of inflammationThis may be of primary pathogenetic significance allowing bacteria to enter the mucus and induce mucosal inflammation. Therefore, a new therapeutic strategy is being developed to substitute the missing mucus PC content in UC. Indeed, a delayed-release PC formulation was able to compensate the lack of PC and improve the inflammatory activityIn randomized controlled studies, delayed-release PC was proven to be clinically and endoscopically effective, which now awaits a phase III authority approval trial.—PMID: 24246994 [PubMed – indexed for MEDLINE]

    Recipe—Mix 1 tsp of sunflower or egg yolk lecithin in a blender and consume this may create a dynamic of health probiotic assisting in the removal of excess stomach build up of genetic materials and bacterial and fungal issues and possibly viral-throught the phospholipids effect as well as the probiotics from the fermented dairy—with both of these as well you may see an increase in intellect and brain efficiency- and an overall immune improvement as well as digestive balance

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     Bone marrow fat tissue secretes hormone that helps body stay healthy

    Date:

    July 3, 2014

    Source:

    University of Michigan Health System

    It has been known for its flavorful addition to soups and as a delicacy for dogs but bone marrow fat may also have untapped health benefits, new research finds.–A University of Michigan-led study shows that the fat tissue in bone marrow is a significant source of the hormone adiponectin, which helps maintain insulin sensitivity, break down fat, and has been linked to decreased risk of cardiovascular disease, diabetes, and obesity-associated cancers. The findings appear in today’s online-ahead-of-print issue of Cell Metabolism.–Bone marrow adipose tissue has primarily been associated with negative health effects, most notably because of a documented relationship to reduced bone mass and increased risks of fractures and osteoporosis. The new study however — which included people with anorexia, patients undergoing chemotherapy, rabbits and mice — suggests that this type of fat may also have benefits.–“These findings are significant because we’ve found that bone marrow adipose tissue may have positive, protective roles, and influence adaptive functions outside of the bone tissue, at least during calorie restriction,” says senior author Ormond MacDougald, Ph.D., the Faulkner Professor in the Department of Molecular & Integrative Physiology, a professor of internal medicine, a member of U-M’s Brehm Center for Diabetes Research, and a Fulbright Scholar at the University of Cambridge in the UK.–“We know that low adiponectin has been correlated with multiple health problems and our findings suggest that an important source of this protein, and potentially others that we haven’t identified yet, is the fat tissue inside bone marrow,” adds co-lead author Erica Scheller, D.D.S. Ph.D., a U-M postdoctoral fellow in the MacDougald lab.-Researchers have long studied the function of our fat, or ‘adipose’ tissue, in hopes of better understanding the link between obesity and ill health. One possible link is adiponectin, a hormone produced by adipose tissue that helps preserve insulin action. High levels of adiponectin are linked to decreased risk of diabetes and cardiovascular disease. People with obesity have the lowest levels of adiponectin — potentially increasing their risk for developing such diseases while the leaner someone gets, the more adiponectin they have.–An outstanding question in the field has been why adiponectin, which is produced by adipose tissue, increases as people lose body fat. A limitation in understanding this paradox is that previous research has focused on peripheral white adipose tissue, which has been believed to be the sole source of adiponectin.

    The new study finds however that bone marrow fat tissue — which increases as body weight falls — is a previously unrecognized source of adiponectin during calorie restriction.–The study found that both marrow adipose tissue and adiponectin increased in humans with anorexia, and in patients undergoing chemotherapy or radiation treatment for ovarian or endometrial cancer. Researchers next used mice to study what happens when marrow fat formation is blocked and also found a relationship between bone marrow adipose tissue and adiponectin, indicating that fat tissue in marrow can have effects beyond the bone.–The research was performed with National Institutes of Health funding in MacDougald’s laboratory at the U-M Medical School, and with collaborators including Clifford Rosen, M.D. of Maine Medical; Mark Horowitz, Ph.D., of Yale University, Anne Klibanski, M.D., of Massachusetts General Hospital; Susanta Hui, Ph.D., of University of Minnesota; and Venkatesh (Gary) Krishnan, Ph.D., of Eli Lilly and Company.-“Bone marrow adipose tissue has traditionally had a bad reputation because of its relationship to decreased bone mass but we now know that adipose tissue within marrow goes beyond the bone and also serves as an endocrine organ that can influence metabolism,” says co-lead author William Cawthorn, Ph.D., a U-M postdoctoral fellow in the MacDougald lab.–“These findings really underscore how little we know about marrow adipose tissue, and also the mechanisms affecting circulating adiponectin levels. This is really just the beginning of much further research to better understand these relationships and their implications.”–Story Source–The above story is based on materials provided by University of Michigan Health SystemNote: Materials may be edited for content and length.–Journal Reference-William P. Cawthorn, Erica L. Scheller, Brian S. Learman, Sebastian D. Parlee, Becky R. Simon, Hiroyuki Mori, Xiaomin Ning, Adam J. Bree, Benjamin Schell, David T. Broome, Sandra S. Soliman, Jenifer L. DelProposto, Carey N. Lumeng, Aditi Mitra, Sandeep V. Pandit, Katherine A. Gallagher, Joshua D. Miller, Venkatesh Krishnan, Susanta K. Hui, Miriam A. Bredella, Pouneh K. Fazeli, Anne Klibanski, Mark C. Horowitz, Clifford J. Rosen, Ormond A. MacDougald. Bone Marrow Adipose Tissue Is an Endocrine Organ that Contributes to Increased Circulating Adiponectin during Caloric RestrictionCell Metabolism, 2014; DOI: 10.1016/j.cmet.2014.06.003

    Recipe—something to explore utilizing soup bones by either pressure cooking them to increase bone marrow access ( adding vinegar or citric acid to the water prior to boiling) may assist in rebuilding the balance between muscle and fat

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    Sound waves harnessed to enable precision micro- and nano-manufacturing

    Date:

    June 24, 2014

    Source:

    RMIT University

    Researcher Dr Amgad Rezk with the lithium niobate chip.

    In a breakthrough discovery, researchers at RMIT University in Melbourne, Australia, have harnessed the power of sound waves to enable precision micro- and nano-manufacturing.–The researchers have demonstrated how high-frequency sound waves can be used to precisely control the spread of thin film fluid along a specially-designed chip, in a paper published today in Proceedings of the Royal Society A.–With thin film technology the bedrock of microchip and microstructure manufacturing, the pioneering research offers a significant advance — potential applications range from thin film coatings for paint and wound care to 3D printing, micro-casting and micro-fluidics.–Professor James Friend, Director of the MicroNano Research Facility at RMIT, said the researchers had developed a portable system for precise, fast and unconventional micro- and nano-fabrication.–“By tuning the sound waves, we can create any pattern we want on the surface of a microchip,” Professor Friend said.–“Manufacturing using thin film technology currently lacks precision ­- structures are physically spun around to disperse the liquid and coat components with thin film.–“We’ve found that thin film liquid either flows towards or away from high-frequency sound waves, depending on its thickness.–“We not only discovered this phenomenon but have also unravelled the complex physics behind the process, enabling us to precisely control and direct the application of thin film liquid at a micro and nano-scale.”–The new process, which the researchers have called “acoustowetting,” works on a chip made of lithium niobate ­- a piezoelectric material capable of converting electrical energy into mechanical pressure.–The surface of the chip is covered with microelectrodes and the chip is connected to a power source, with the power converted to high-frequency sound waves. Thin film liquid is added to the surface of the chip, and the sound waves are then used to control its flow.–The research shows that when the liquid is ultra-thin ­- at nano and sub-micro depths — it flows away from the high-frequency sound waves. The flow reverses at slightly thicker dimensions, moving towards the sound waves. But at a millimetre or more in depth, the flow reverses again, moving away.–Video: http://www.youtube.com/watch?v=IQ762VTxD2g&feature=youtu.be

    Story Source-The above story is based on materials provided by RMIT University. —Journal Reference-Amgad R. Rezk, Ofer Manor; Leslie Y. Yeo, and James R. Friend. Double Flow Reversal in Thin Liquid Films Driven by MHz Order Surface VibrationProceedings of the Royal Society A, 25 June 2014

    Special Comment —with this type of technology the inverse of what can be done is a reality as well with nanoparticles being absorbed in the body through chemtrails-foods-cosmetics-vaccines these frequencies can cause a reaction within the scope of your cells and tissue—this needs to be addressed since this is what is ongoing daily

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    Cocoa extract may counter specific mechanisms of Alzheimer’s disease

    Date:

    June 23, 2014

    Source:

    Mount Sinai Medical Center

    A specific preparation of cocoa-extract called Lavado may reduce damage to nerve pathways seen in Alzheimer’s disease patients’ brains long before they develop symptoms, according to a study conducted at the Icahn School of Medicine at Mount Sinai and published June 20 in the Journal of Alzheimer’s Disease (JAD).–Specifically, the study results, using mice genetically engineered to mimic Alzheimer’s disease, suggest that Lavado cocoa extract prevents the protein β-amyloid- (Aβ) from gradually forming sticky clumps in the brain, which are known to damage nerve cells as Alzheimer’s disease progresses.–Lavado cocoa is primarily composed of polyphenols, antioxidants also found in fruits and vegetables, with past studies suggesting that they prevent degenerative diseases of the brain.–The Mount Sinai study results revolve around synapses, the gaps between nerve cells. Within healthy nerve pathways, each nerve cell sends an electric pulse down itself until it reaches a synapse where it triggers the release of chemicals called neurotransmitters that float across the gap and cause the downstream nerve cell to “fire” and pass on the message.–The disease-causing formation of Aβ oligomers — groups of molecules loosely attracted to each other -build up around synapses. The theory is that these sticky clumps physically interfere with synaptic structures and disrupt mechanisms that maintain memory circuits’ fitness. In addition, Aβ triggers immune inflammatory responses, like an infection, bringing an on a rush of chemicals and cells meant to destroy invaders but that damage our own cells instead.–“Our data suggest that Lavado cocoa extract prevents the abnormal formation of Aβ into clumped oligomeric structures, to prevent synaptic insult and eventually cognitive decline,” says lead investigator Giulio Maria Pasinetti, MD, PhD, Saunders Family Chair and Professor of Neurology at the Icahn School of Medicine at Mount Sinai. “Given that cognitive decline in Alzheimer’s disease is thought to start decades before symptoms appear, we believe our results have broad implications for the prevention of Alzheimer’s disease and dementia.-Evidence in the current study is the first to suggest that adequate quantities of specific cocoa polyphenols in the diet over time may prevent the glomming together of Aβ into oligomers that damage the brainas a means to prevent Alzheimer’s disease.–The research team led by Dr. Pasinetti tested the effects of extracts from Dutched, Natural, and Lavado cocoa, which contain different levels of polyphenols. Each cocoa type was evaluated for its ability to reduce the formation of Aβ oligomers and to rescue synaptic function. Lavado extract, which has the highest polyphenol content and anti-inflammatory activity among the three, was also the most effective in both reducing formation of Aβ oligomers and reversing damage to synapses in the study mice.–“There have been some inconsistencies in medical literature regarding the potential benefit of cocoa polyphenols on cognitive function,” says Dr. Pasinetti. “Our finding of protection against synaptic deficits by Lavado cocoa extract, but not Dutched cocoa extract, strongly suggests that polyphenols are the active component that rescue synaptic transmission, since much of the polyphenol content is lost by the high alkalinity in the Dutching process.”–Because loss of synaptic function may have a greater role in memory loss than the loss of nerve cells, rescue of synaptic function may serve as a more reliable target for an effective Alzheimer’s disease drug, said Dr. Pasinetti.–The new study provides experimental evidence that Lavado cocoa extract may influence Alzheimer’s disease mechanisms by modifying the physical structure of Aβ oligomers. It also strongly supports further studies to identify the metabolites of Lavado cocoa extract that are active in the brain and identify potential drug targets.–In addition, turning cocoa-based Lavado into a dietary supplement may provide a safe, inexpensive and easily accessible means to prevent Alzheimer’s disease, even in its earliest, asymptomatic stages.–Story Source- The above story is based on materials provided by Mount Sinai Medical CenterJournal Reference-Wang J, Varghese M, Ono K, Yamada M, Levine S, Tzavaras N, Gong B, Hurst WJ, Blitzer RD, Pasinetti GM. Cocoa Extracts Reduce Oligomerization of Amyloid-β: Implications for Cognitive Improvement in Alzheimer’s DiseaseJ Alzheimers Dis, June 2014 DOI: 10.3233/JAD-132231

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    Ceremonial PTSD therapies favored by Native American veterans

    Date:

    June 30, 2014

    Source:

    Washington State University

    Urquhart is a Native veteran and graduate student in the WSU College of Education.-Native American veterans battling Post Traumatic Stress Disorder find relief and healing through an alternative treatment called the Sweat Lodge ceremony offered at the Spokane Veterans Administration Hospital.-In the Arizona desert, wounded warriors from the Hopi Nation can join in a ceremony called Wiping Away the Tears. The traditional cleansing ritual helps dispel a chronic “ghost sickness” that can haunt survivors of battle.-These and other traditional healing therapies are the treatment of choice for many Native American veterans, — half of whom say usual PTSD treatments don’t work — according to a recent survey conducted at Washington State University. The findings will be presented at the American Psychological Association conference in Washington D.C. this August.

    The study is available online at https://www.surveymonkey.com/s/nativeveterans.

    Led by Greg Urquhart and Matthew Hale, both Native veterans and graduate students in the College of Education, the ongoing study examines the attitudes, perceptions, and beliefs of Native American veterans concerning PTSD and its various treatment options. Their goal is to give Native veterans a voice in shaping the types of therapies available in future programs.-“Across the board, Native vets don’t feel represented. Their voices have been silenced and ignored for so long that they were happy to provide feedback on our survey,” said Hale.-Historically, Native Americans have served in the military at higher rates than all other U.S. populations. Veterans are traditionally honored as warriors and esteemed in the tribal community.-A 2012 report by the Department of Veterans Affairs showed that the percentage of Native veterans under age 65 outnumbers similar percentages for veterans of all other racial groups combined.-The WSU survey provides a first-hand look at the veterans’ needs, but more importantly, reveals the unique preferences they have as Native American veterans, said Phyllis Erdman, executive associate dean for academic affairs at the college and mentor for the study.

    Cultural worldview

    Urquhart said many Native veterans are reluctant to seek treatment for PTSD because typical western therapy options don’t represent the Native cultural worldview.-“The traditional Native view of health and spirituality is intertwined,” he explained. “Spirit, mind, and body are all one — you can’t parcel one out from the other — so spirituality is a huge component of healing and one not often included in western medicine, although there have been a few studies on the positive effects of prayer.“-For many years, the U.S. government banned Native religious ceremonies, which subsequently limited their use in PTSD programs, said Urquhart. Seeking to remedy the situation, many Veterans Administration hospitals now offer traditional Native practices including talking circles, vision quests, songs, drumming, stories, sweat lodge ceremonies, gourd dances and more. Elders or traditional medicine men are also on staff to help patients process their physical and emotional trauma.-“PTSD is a big issue and it’s not going away anytime soon,” said Hale who identifies as Cherokee and was a mental health technician in the Air Force.-Urquhart, who is also Cherokee and developed mild symptoms of PTSD after a tour as a cavalry scout in Iraq, said there have been very few studies on Native veterans and PTSD. He and Hale designed their survey to be broader and more inclusive than any previous assessments. It is the first to address the use of equine therapy as a possible adjunct to both western treatments and Native ceremonial approaches.

    Standard treatments disappointing

    So far, 253 veterans from all five branches of the military have completed the survey, which includes 40 questions, most of them yes or no answers. It also includes an open-ended section where participants can add comments. The views reflect a diverse Native population ranging from those living on reservations to others who live in cities.-The majority of survey takers felt that “most people who suffer from PTSD do not receive adequate treatment,” said Urquhart. For Native veterans who did seek standard treatment, the results were often disappointing. Sixty percent of survey respondents who had attempted PTSD therapy reported “no improvement” or “very unsatisfied.”-Individual counseling reportedly had no impact on their PTSD or made the symptoms worse for 49 percent of participants. On the other hand, spiritual or religious guidance was seen as successful or highly successful by 72 percent of Native respondents. Animal assisted therapy — equine, canine, or other animals — was also highly endorsed.-“The unique thing about equine therapy is that it’s not a traditional western, sit-down-with-a-therapist type program. It’s therapeutic but doesn’t have the stigma of many therapies previously imposed on Native Americans,” said Urquhart.-Strongly supportive of such efforts, Erdman is expanding the long-running WSU Palouse Area Therapeutic Horsemanship (PATH) program to include a section open to all veterans called PATH to Success: A Warrior’s Journey.

    Giving veterans a voice

    Urquhart, Hale, and teammate, Nasreen Shah say their research is gaining wide support in Native communities throughout the nation.-The team plans to distribute the survey results to all U.S. tribes, tribal governments, Native urban groups, and veteran warrior societies. They also hope the departments of Veterans Affairs and Indian Health Services will take notice and continue to incorporate more traditional healing methods into their programs.-As one Iroquois Navy veteran commented on the survey, “Traditional/spiritual healing can be very effective together with in depth education and background in modern treatment methods.”-A Nahua Army veteran agreed, writing, “Healing ceremonies are absolutely essential, as is story telling in front of supportive audiences. We need rituals to welcome back the warriors.”-Story Source-The above story is based on materials provided by Washington State University. The original article was written by Rebecca E. Phillips. Note: Materials may be edited for content and length.

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    Future soldiers could be protected against germ warfare by genetically modified blood cells

     Steve Connor

    Monday, 30 June 2014

    Soldiers on future battlefields could be protected against germ warfare agents by having blood transfusions with genetically modified cells that can neutralise deadly biological toxins, scientists have found.—-Human red blood cells have been genetically engineered to produce protein antidotes and other antibody-based medicines that can be safely delivered to any part of the body, researchers said.—A study has shown that the technique works well when carried out on laboratory mice, and that modified human stay circulating in the body for up to four months, giving transfusion patients long red blood cells -term protection, they said.—Red blood cells normally carry oxygen from the lungs to the living tissues and are the most numerous of all the cells, accounting for about a quarter of the 100 trillion cells of the human body. They are deliberately small and flexible to allow them to flow through narrow capillaries.–They also lack their own chromosomes because the red cell nucleus is lost during development, making any genetic modification inherently safer as they cannot replicate to produce a cancerous tumour and are naturally removed from the bloodstream after four months.–“We wanted to create high-value red cells that do more than simply carry oxygen. Here we’ve laid out the technology to make mouse and human red blood cells in culture that can express what we want and potentially be used for therapeutic or diagnostic purposes,” said Harvey Lodish of the Whitehead Institute for Biomedical Research in Massachusetts.–A study published in the journal Proceedings of the National Academy of Sciences shows that it is possible to use human red blood cells as microscopic vehicles for carrying a cargo of genetically engineered proteins in the cell’s outer membrane that can be targeted against specific toxins.--The research was supported by the US Defence Research Projects Agency (Darpa), the scientific funding arm of the US military, which is interested in developing the technology for future treatments or vaccines against biological weapons, the researchers said.–“Because the modified human red blood cells can circulate in the body for up to four months, one could envision a scenario in which the cells are used to introduce antibodies that neutralise a toxin. The result would be long-lasting reserves of antitoxin antibodies,” said Hidde Ploegh, professor of biology at the Massachusetts Institute of Technology, one of the study’s senior authors.–The researchers made the genetic modifications to the precursor cells that develop into fully mature red blood cells. The technique could also be used to produce modified red cells engineered to remove bad cholesterol from the blood stream, to carry clot-busting proteins to treat strokes or deep-vein thrombosis or to deliver anti-inflammatory antibodies to alleviate chronic inflammation, the researchers said.–“Moreover, the established safety of blood transfusions inspires confidence that these engineered red blood cells indeed will find use in humans,” they said.—

    Special Comment –this whole thing is a farce—in order to inject anything one would need to know in advance what the enemy had in there biological arsenal that was going to be released this at best with be a hypothesis—and as a result the wrong mix would be in the blood and may in  fact expedite the effect of what is being released

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    Exposure to a high fat diet in the womb could reduce anxiety  and stress in adolescence, according to new research in rats  

    #785
    Avatarwebmaster
    Keymaster

    The new results are contrary to earlier studies in adult rats which established a link between exposure to a high fat diet (HFD) and increased anxiety behaviour.However the new research, which examined the influence of maternal HFD on several measures of anxiety behaviour and gene development in adolescent offspring, found that the offspring of rats parentally exposed to HFD exhibited reduced levels of anxiety and this was especially the case in females The data suggests that adolescence constitutes an additional period when the effects of developmental programming may modify mental health trajectories the authors said Anxiety levels are controlled by corticosteroids (like glucocorticoid receptors – GR) in the limbic regions of the brain that control the body’s ability to reduce or increase inflammation and stress levels (the amygdala and hippocampus Previous studies on adult rats identified increased anxiety when exposed to a HFD, as well as increased inflammation The new latest data could suggest ‘a developmental shift’ between adolescence and adulthood in the effects of HFD on anxiety, said the team  offspring less anxious Ten adult female rats (or dams) were placed on a HFD consisting of 60% fat, 20% protein and 20% carbohydrate and another 10 were exposed to the control house chow diet (CHD) comprising 3.5% fat, 28.5% protein, and 58% carbohydrate  The rats started the diet four weeks before mating and throughout pregnancy and lactation and were subjected to three behavioural tests to gauge their responses to potentially stressful scenarios Results revealed a greater abundance of GR in the hippocampus among HFD-exposed male and female offspring compared to CHD offspring – with levels were significantly higher in females Adolescent analysis of corticosteroid receptors revealed that hippocampal GR expression was increased in HFD-exposed offspring, particularly in females, which supports our behavioral results indicating decreased anxiety among HFD-exposed offspring said the report There were no significant differences in GR gene activity in the amygdala of HFD-exposed adolescents Faster weight gain Dams-fed HFD gained more weight than CHD dams throughout gestation. There was no difference in body weight of the pups from either group at birth but those from HFD dams put on weight faster than CHD pups prior to weaning However by the time the ‘pups’ reached adolescent there was no discernible difference in body weight between the groups The researchers added:  This suggests our findings are attributable to parental HFD exposure rather than differences in current body weight

     

    #786
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    Keymaster

    Eight ways zinc affects the human body

    Date:

    July 18, 2014

    Source:

    Institute of Food Technologists (IFT)

    Researchers identified zinc as one of the most important essential trace metals in human nutrition and lifestyle in a new review article in Comprehensive Reviews in Food Science and Food Safety, published by the Institute of Food Technologists (IFT). Zinc is not only a vital element in various physiological processes; it is also a drug in the prevention of many diseases.—The adult body contains about two to three grams of zinc. It is found in organs, tissues, bones, fluids, and cellsFoods with high protein content, specifically animal protein, are major sources of zinc in the human diet. Zinc can also be used as fortification for other foods as well. Nearly half of the world’s population is at risk for inadequate zinc intake. The article reviewed numerous studies that showed a relationship between zinc and vital human physiological processes such as the following:

    Brain: The blood zinc level is less in patients with Alzheimer’s and Parkinson’s disease (Brewer, and others 2010).In a rodent study, it was observed that zinc behaves like an antidepressant (Nowak and others, 2005).

    Cardiovascular System: Zinc performs a noteworthy role in the regulation of arterial blood pressure. Males and females were reported to metabolize zinc differently when suffering from hypertension (Tubek, 2007).

    LiverZinc deficiency in the liver occurs not only in those with liver cirrhosis, but also in less advanced alcoholic and nonalcoholic liver disease (Bode and others, 1998).

    Pregnancy: A mild deficiency of zinc during a pregnancy can cause increased maternal morbidity, abnormal taste sensation, prolonged gestation, inefficient labor, atonic bleeding, and an increased risk to fetuses (Jameson, 1993).

    DiabetesZinc is very important in the synthesis, storage, and secretion of insulin (Chausmer 1998). A low level of zinc has been shown to play a role in diabetics with associated disease conditions such as coronary artery disease and several related risk factors including hypertension, and elevated levels of triglycerides (Singh and others, 1998).

    Endocrine System: Studies show a correlation between zinc deficiency in geriatric patients and reduced activity of the thymus gland and thymic hormones, decreased response to vaccinations, and reduced immunity (Haase and Rink, 2009).

    Healing: Zinc deficiency has been linked with delayed wound healing, and has been found to be crucial to the healing of gastric ulcers especially at the early stage (Kennan and Morris, 1993; Andrews and Gallagher-Allred, 1999; Watanabe, 1995).

    PneumoniaZinc may shorten the duration of severe pneumonia and time in the hospital (Brooks, 2004).

    Story Source-The above story is based on materials provided by Institute of Food Technologists (IFT)Note: Materials may be edited for content and length.-Journal Reference-Kuljeet Kaur, Rajiv Gupta, Shubhini A. Saraf, Shailendra K. Saraf. Zinc: The Metal of LifeComprehensive Reviews in Food Science and Food Safety, 2014; 13 (4): 358 DOI: 10.1111/1541-4337.12067

    Suggestions—zinc citrate—zinc picolinate—zinc cysteine-zinc ascorbate—would be effective for immune response and support and for insulin regulating

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    Iodine may alleviate swelling in retinitis pigmentosa patients’ retinas

    Date:

    July 21, 2014

    Source:

    Massachusetts Eye and Ear Infirmary

    Cystoid macular edema (CME) is a common complication of retinitis pigmentosa (RP), a family of retinal diseases in which patients typically lose night and side vision first and then develop impaired central vision. CME can also decrease central vision. Current treatments for CME in RP are not always effective and can lead to adverse results.—Researchers from the Massachusetts Eye and Ear, Harvard Medical School, and Boston University School of Medicine tested whether the extent of retinal swelling due to CME was inversely related to dietary iodine intake in patients with RP and found that it was. This finding raises the possibility that an iodine supplement could help limit or reduce central foveal swelling in RP patients with CME. Their results are presented online in the July issue of JAMA Ophthalmology.–Past research performed on a previous population showed an inverse association between the presence of CME and reported iodine supplementation in RP patients. This finding and physiology research by others pointed to iodine as being worth investigating further. In the present experiment, the researchers performed a cross-sectional observational study of 212 nonsmoking patients 18 to 69 years of age who were referred to Mass. Eye and Ear for RP with visual acuity of no worse than 20/200 in at least one eye. They used optical coherence tomography to measure central foveal swelling due to CME in the patients. Total dietary intake of iodine was estimated from multiple (preferably, 10) spot urine samples collected at home.–The investigators found that the magnitude of central foveal swelling due to CME was inversely related to urinary iodine concentration when emphasizing data with more reproducible urinary iodine concentrations (p<.001) — patients with the lowest urinary iodine levels tended to have retinas with the most swelling.–“Additional study is required to determine whether an iodine supplement can limit or reduce the extent of CME in patients with RP,” said Michael A. Sandberg, Ph.D., lead author of the study and senior scientist in the Berman-Gund Laboratory for the Study of Retinal Degenerations at Massachusetts Eye and Ear and Associate Professor of Ophthalmology at Harvard Medical School.–Story Source-The above story is based on materials provided by Massachusetts Eye and Ear InfirmaryNote: Materials may be edited for content and length.–Journal Reference–Michael A. Sandberg, Elizabeth N. Pearce, Shyana Harper, Carol Weigel-DiFranco, Lois Hart, Bernard Rosner, Eliot L. Berson. The Relationship of Central Foveal Thickness to Urinary Iodine Concentration in Retinitis Pigmentosa With or Without Cystoid Macular EdemaJAMA Ophthalmology, 2014; DOI: 10.1001/jamaophthalmol.2014.1726

    Suggestion—when using the lugols apply 1-4 drops a day in divided doses and go up to 10 drops daily—you can see if this will be effective—if you find it is suffice at 6-7 drops then that will be all you need and maintain this for several months—cycling off or reducing as needed—this should be an effective method—you can increase or decrease the dose as you see fit—if there should be a issue with the heart as a palpitation then increase the use of magnesium

    This is a suggested method and any use of the information is the sole responsibility of the individual applying these or any other method

    There should be no issue but anything excessive maybe a issue in imbalancing the body so use this in increments and moderate your results with the use

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    Antidiabetic effects of chamomile flowers extract in obese mice through transcriptional stimulation of nutrient sensors of the peroxisome proliferator-activated receptor (PPAR) family.

    PLoS One. 2013;8(11):e80335

    Authors: Weidner C, Wowro SJ, Rousseau M, Freiwald A, Kodelja V, Abdel-Aziz H, Kelber O, Sauer S

    Abstract
    Given the significant increases in the incidence of metabolic diseases, efficient strategies for preventing and treating of these common disorders are urgently needed. This includes the development of phytopharmaceutical products or functional foods to prevent or cure metabolic diseases. Plant extracts from edible biomaterial provide a potential resource of structurally diverse molecules that can synergistically interfere with complex disorders. In this study we describe the safe application of ethanolic chamomile (Matricaria recutita) flowers extract (CFE) for the treatment and prevention of type 2 diabetes and associated disorders. We show in vitro that this extract activates in particular nuclear receptor peroxisome proliferator-activated receptor gamma (PPARγ) and its isotypes. In a cellular context, in human primary adipocytes CFE administration (300 µg/ml) led to specific expression of target genes of PPARγ, whereas in human hepatocytes CFE-induced we detected expression changes of genes that were regulated by PPARα. In vivo treatment of insulin-resistant high-fat diet (HFD)-fed C57BL/6 mice with CFE (200 mg/kg/d) for 6 weeks considerably reduced insulin resistance, glucose intolerance, plasma triacylglycerol, non-esterified fatty acids (NEFA) and LDL/VLDL cholesterolCo-feeding of lean C57BL/6 mice a HFD with 200 mg/kg/d CFE for 20 weeks showed effective prevention of fatty liver formation and hepatic inflammation, indicating additionally hepatoprotective effects of the extractMoreover, CFE treatment did not reveal side effects, which have otherwise been associated with strong synthetic PPAR-targeting molecules, such as weight gain, liver disorders, hemodilution or bone cell turnover. Taken together, modulation of PPARs and other factors by chamomile flowers extract has the potential to prevent or treat type 2 diabetes and related disorders.–PMID: 24265809 [PubMed – indexed for MEDLINE]

    Recipe—make a ethanolic alcohol extract— see the herbal extract video on youtube–

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    Adults with eosinophilic esophagitis should consider a diet change

    Date:

    July 18, 2014

    Source:

    American Gastroenterological Association

    Dietary elimination is a successful method of treatment for adults with eosinophilic esophagitis (EoE), according to a new study in Clinical Gastroenterology and Hepatology, the official clinical practice journal of the American Gastroenterological Association.—“By eliminating specific foods from patients’ diets, symptoms improved in 71 percent of patients, and endoscopic appearance improved in 54 percent,” said lead study author, W. Asher Wolf, MD, MPH, and co-author Evan S. Dellon, MD, MPH, from the division of gastroenterology and hepatology, University of North Carolina School of Medicine. “These strong results support dietary elimination therapy as an effective treatment for adults suffering from EoE.”–Researchers conducted a retrospective cohort study using the University of North Carolina EoE database from 2006-2012. Subjects were 18 years of age or older and diagnosed with EoE based on consensus guidelinesThe study analyzed two diet elimination plans. For the first therapy — targeted elimination — patients underwent evaluation with skin prick testing, and foods that had a positive reaction, as well as any foods identified by patient self-report as being possible triggers regardless of the severity of response, were eliminated. For the other diet prescribed — the six-food elimination diet — dairy, wheat, eggs, soy, nuts and seafood were eliminated from the patient’s diet regardless of skin-prick test results.—Sixty-eight percent of patients who received targeted diet elimination experienced symptom improvement, compared with 78 percent of those who followed a six-food elimination diet plan. For those subjects who responded to six-food elimination diet, one food (or food group) was added back every six weeks, and endoscopy was repeated. Eggs and dairy were found to be the most common triggers, both impacting 44 percent of patients.—–Importantly, because this study included patients who failed steroid therapy, the overall study population likely represents harder to treat EoE patients. The success of dietary elimination in this population indicates its utility for therapy in patients resistant to steroids.–Because EoE is an allergen/immune mediated condition, dietary elimination therapy has been extensively studied in children and is now a well-established modality in pediatric patients. Until recently, the utility of dietary elimination was unknown in adults. However, evidence is mounting; a June 2014 Gastroenterology meta-analysis2 reported that dietary interventions are effective in producing histologic remission in both pediatric and adult patients with EoE.

    While the current treatment of swallowed corticosteroids acts topically to reduce esophageal inflammation, no corticosteroid is FDA approved, not all patients respond and, when discontinued, EoE almost always recurs. As such, there is a growing need for a new treatment for patients with EoE.–Further research should emphasize which factors can predict effective dietary therapy, to target therapy to patients most likely to respond.-Story Source–The above story is based on materials provided by American Gastroenterological AssociationNote: Materials may be edited for content and length.–Journal Reference-W. Asher Wolf, Maya R. Jerath, Sarah L.W. Sperry, Nicholas J. Shaheen, Evan S. Dellon. Dietary Elimination Therapy Is an Effective Option for Adults With Eosinophilic EsophagitisClinical Gastroenterology and Hepatology, 2014; 12 (8): 1272 DOI: 10.1016/j.cgh.2013.12.034

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    The role of dairy in maintaining adult bone and skeletal muscle health

    Date:

    July 28, 2014

    Source:

    Taylor & Francis

    Understanding that diets are often built around food groups rather than specific nutrients, researchers from Switzerland, France, and North America decided to examine interactions between four nutrients found in dairy products and their role in preserving bone and skeletal muscle. Their Open Access article with these findings, “Dairy in Adulthood: From Foods to Nutrient Interactions on Bone and Skeletal Muscle Health,” is now available in the Journal of the American College of Nutrition, the Official Publication of the American College of Nutrition and a publication from Routledge.–Calcium (Ca), inorganic phosphate (Pi), vitamin D, and protein are nutrients that impact bone and skeletal muscle integrity. Deficiency in the supply of these nutrients increases with aging. Dairy foods are rich in Ca, Pi, and proteins and in many countries are fortified with vitamin D. Dairy foods are important sources of these nutrients and go a long way to meeting the recommendations, which increase with aging. This review emphasizes the interactions between these 4 nutrients, which, along with physical activity, act through cellular and physiological pathways favoring the maintenance of both bone and skeletal muscle structure and function.–While bone health is often associated with calcium alone, Calcium’s interactions with inorganic phosphate, vitamin D, and protein are important components of beneficial dairy consumption. Combined vitamin D and calcium supplementation has been shown to reduce the incidence of hip and other non-vertebral fractures among older populations, with some studies suggesting that vitamin D actually leads to lower rates of falling in subjectsDietary protein, while often associated solely with muscle recovery, also promotes bone formation by stimulating both Ca and Pi intestinal absorption and the production of a bone growth factor. And while vitamin D deficiency is associated with muscle weakness, vitamin D and protein supplementation are required together to improve strength.–Combining the four above-mentioned nutrients with physical activity decreases the likelihood of bone and muscle degeneration-related injury in older adults. Dairy products are a convenient way to work them into a diet, as they contain Ca, Pi, and protein at levels comparable to recommended intakes, and are fortified with vitamin D.–Story Source-The above story is based on materials provided by Taylor & FrancisNote: Materials may be edited for content and length.–Journal Reference-Jean-Philippe Bonjour, Marius Kraenzlin, Régis Levasseur, Michelle Warren, Susan Whiting. Dairy in Adulthood: From Foods to Nutrient Interactions on Bone and Skeletal Muscle HealthJournal of the American College of Nutrition, 2013; 32 (4): 251 DOI: 10.1080/07315724.2013.816604

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    Milk does a Body Good– we are going to take dairy and show how to use this to make it better and wholesome— Now the best milk to consume is Unpasteurized Milk —the store bought homogenized is basically a leftover milk byproduct—and not even milk—Now if you cannot get Unpasteurized Milk due to Gov’t Stupidity—and regulations—then utilize kefir or yogurt or buttermilk with fat—the effects will not be as pronounced but will still benift

    Here are some remedies to try to build and restore the body

    ùFor children take full fat yogurt or kefir 16 oz added to a blender add 1 tsp of gelatin and 1 tablespoon of coconut oil or mct oil—adding wheat germ oil would be good as well—mix in blender and when down ad 1 drop of iodine to the mix after and stir in with either a wooden spoon or chopstick—consume

    ùIf you can get unpasteurized milk 16 oz then add 1 egg ( farmer bought –and orange or reddish yolk)  add cinnamon to this and wheat germ oil  blend til mixed then after add your iodine— optional add shilajit or fulvic minerals to this to further make these minerals more readily absorbable

    ùButtermilk—add glycerol and shila jit-leucine about ¼ tsp and lipase enzyme ¼ tsp—blend together —this will again more readily taken in

    ùCottage Cheese –full fat 16 oz add to it berries and minerals capsule(s) —B complex 1-3 capsules-and some berry( of choice—avoid strawberries unless home grown or chemical free) add distilled water if necessary and blend

    ùùin any of these combinations have a potato with this –broiled—baked or mashed—and this will be a complete meal

    ùùùif you have no choice and are stuck then use powdered milk—add the gelatin and fat to this and minerals and b vitamins to make your self a real milk product

    ùùCanned Milk can be utilized as well –by again adding fat and nutrients—

    ùto increase Phosphorus—the egg will do this —sunflower leicithin—or even TSP—if you wish to flavour this then add vanilla or almond extract as some suggestions—to increase fat heat the butter scoop out the cream and add the oil

    and if you wish add your cq 10 to this and vitamin A and D

    #787
    Avatarwebmaster
    Keymaster

    ****************************************************************************

    Kidney Stones

    Citric Acid –will dissolve stones—by using  ¼ tsp in water and drunk 4-5 times a day—-the use of magnesium citrate and potasium citrate or a sodium citrate will also assist in the breaking this down—eliminating things like beer-spinach-peanuts-and beets for a period time allowing the kidneys to flush out the crystals

    Using as well distilled water or reverse osmosis to keep the water clean and to allow for flushing and not adding harmful metals

    **********************************************************************

    Teeth Restore

    Use 10 grams of TSP ( 2 tsp) 90 grams( 6 tablespoon)—mixed in 24-30 oz distilled water –dissolve—and use a ¼ cup at a time –can be diluted with tap water if to strong—use as a oil pulling pushing this through the teeth and drawing

    Do not brush—repeat the process 5-7 times—you may see specks of polymers pop out of the mouth—you may see fibres come out—what you may see as well is a reversal of cavity damage and a regrowth—internally you will as well utilize the ascorbate mineral mix to replenish the loss of vitamin C and the use of  essential mineral building blocks—magnesium citrate-potassium citrate –boron( borax) TSP ( trisdium phosphate for both sodium and phosphorus) zinc citrate- and baking soda—this done internally will assist in the materials required to upbuild—the elimination of all grains and cereals and breads—and soy are imperative to seeing success—the use of gelatin –will also benefit—nothing with microwave or canola and soybean oils since they are destructive to thyroid—and pancreas stomach-thymus—process foods are to be avoided as well

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    Fat—what to use when doing ketosis—

    Lipase should be incorporated with any fats to assist to break down and conversion of hormones and the use of  fats for cellular health and energy for the organs— other things to consider as well would be B5-for energy and fat use and hormonal production—Choline-to regulate the fat usage –L carnitine to convert the fat for energy production- taurine to increase Bile salt production- and sunflower or egg yolk lecithin to control the flow of fat as well—other supplements you may want to take with fat are cq10-Vitamin A-( strongly encourage) Vitamin D ( minimal amounts 400-1000IU) Vitamin E( none soy sourced) essential oil of rosemary-sage-thyme-orange- tangerine-BHT as antioxidants to slow down the break down of the fat so it remains effective longer in the body before it becomes periodized( broken down) and the use of rosemary-bay leaf- thyme-garlic-onion-sage-to again assist in the sustaining the fat and the uses

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    Toxic –cleaning agents that are supposed to be Dangerous

     

    TSP –sodium and phosphorus

    Ascorbic Acid– Vitamin C derivative-antioxidant

    Vinegar—Anti mold –Kills HIV –and is used as an industrial Cleaner

    Iodine—body support overall –used as an industrial cleaner

    Turpentine-essential oil of pine-balsaam fir-spruce—Potent antioxidants-supports male endocrine system –kills off harmul pathogens in the body

    Used as an industrial cleaner to sanitize and to remove vermin

    Colloidal Silver-Colloidal Copper—high powered anti fungals-anti algaeicides-anti bacterial—anti microbial-anti virals—used in the medical settings as industrial cleaning agents

    Hydrogen Peroxide – pro oxidant—antioxidant—used as an industrial cleaner to remove a host of conditions

    MMS- sodium chlorite used as a industrial cleaner to kill off all kinds of pathogenic infections

    Baking Soda—used as a cleaning agent –used in the body to remove fungal over growth –cancer eliminator and digestive aide

    Thyme and Mint- have been used as a cleaning and sanitizing agents but when and as a oral sanitizer

    White Wine—used as an industrial cleaning agent used to reduce or clean Mold

    STS-Sodium Thiolsulphate—used as an industrial cleaner to remove chlorine and used in photography—and paper industry—used as a potent chelating agent for the body removing harmful build up of chemical dust and metals and radioactivity

    EDTA—used as an industrial cleanser in removing metal ions—and is used as well for chelating metals and some chemicals in the Body

    Borax-used as a cleaning agent and detergent additive—is also used by the body to heal and regenerate and combines with magnesium to assist with bone health and regulates hormones

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    Hydrator internal and external—when going outside and are being exposed to Microwave heat and Hot days and Chemtrails this can have a frying effect on the system allowing the cells to become saturated with the fall out and radiation –so what you want to do is to take glycerin or glycerol and mix lugols iodine with this and apply topically to the skin—take 1 oz of glycerol 10-20 drops of iodine and mix well—you can screw the top of the container if you put it in a 1 oz seal top and either chake or percuss about 100 times the apply—you can wet the areas first with water and then apply allowing this to dry on it’s own sealing the cells with the water and the iodine and glycerol— you can take a tsp of this orally—you can modify by adding TSP –or other electrolytes with the iodine as well —this will alow for sustained hydration-ATP production( energy for the cells) and electrolyte and hydration not to mention anti radiation effect of the iodine

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    Liquid diets— what to do to safely clear out and nourish and build with a compromised digestive system—so what would you use—here are several things you can use to assist you—Meat Extracts—take meat—lean—puncture the meat or slice it –then add to a jar—and lightly seal the jar –add to a pot and allow to boil or high simmer for several hours and then when done pour the liquid content to a jar- season with salt if you wish and use tsp increments—Juices utilze and veg or fruit juice and when done add some gelatin to this to increase the mineral uptake and protein along with the antioxidant and vitamin content—an alternative is to allow the juices to break down and ferment so that the sugars can be reduced and the mineral or antioxidant content can increase allowing for better uptake of the nutrients-this will assist in restoration in a lot of areas—Gelatin broths —heating water and dissolving gelatin in distilled water and when dissolved utilize as a beverage—can and herbals as well as minerals with this combination to rebuild muscle-organ-bone and tissue—Fermented Dairy—yogurt-kefir-sour creams—cheese—can be utilized as well in the repairing and regenerating the immune system—repairing the colon—regrowing a colon—cleansing the system and utilizing minerals and proteins and fas more efficiently —can utilize sugars as well to increase bacterial levels—will see butyric acds and lactic acids for killing off cancers — Teas and  Herbal Fusions—making teas and using either one or several herbs at a time to increase the desired effect —will release minerals—as well as antioxidants—and vitamins—depending on the combination some will just steep others will boil—Soups which are essential fusions but with a mix of protein and carbs and veges are another way to increase nutrients in a way where one is compromised can see vitality levels return- Protein Drinks or Smoothies can also be utilized as a means of getting high dense nutrients into the body—by adding a fermented dairy with this —can see a more readily use and uptake of the proteins and other minerals mixed with this combination

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    Labourers Health— this one is going to be diverse but you will have to utilize the basics to assist you with your daily labours—the one thing all labours need are antioxidants—and the cheapest and most effective of them will be Ascorbic Acid and Sulphur—and the easiest Sulphur is MSM—and the other important power vitamin is B1—this combination can remove toxic build up of industrial and environmental pollutants that labourers are exposed to

    The minimum dail dose is about  1 gram-1000mgs-1/4 tsp of Ascorbic acid with ¼ tsp of MSM and 100mgs of B1 taken several timesa day usually a minimum of 5 times a day—this may see recovery as well as healing and cleansing effect of the toxins—Food wise depending on the type of labour—should be Protein—then Fat—then fruit or vegs—Breads—Cereals—Pastas—Rice-Corn will be counter productive—consuming either onion—or garlic or ginger with the protein whether in drink as a tea or a juice or mixed with foods will increase much needed Testosterone for men and some for women which will incorporate the proteins more effectively in the muscles—and fruit –berries—cherries—citrus fruits which will have a good mineral content of magnesium and potassium –any apple or pear—or  fruits in general—the ones to avoid are banaas –grapes-raisons –watermelon and dates—these have to a high glycemic rate and can be problematic –fats to utilize are the saturated fats—for long term power and energy for the muscles to work—incorporating lipase-to insure usage-B5 – Taurine- Choline-L carnitine will insure the use of the fats for energy  –taking these daily in 250-500mgs with meals will increase the use—the lipase being the exception—only need between this can be taken in increments of 1-4 hundred mgs- to insure a good break down of the fats—which can increase fecal volume leaving the tract—the consumption of yogurt and kefir and cottage cheese and cheeses can also increase probiotic activity as well as protein and fats required for stamina and strength—these can be utilized as well

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    Keymaster

    Effect of icariin on osteoblastic differentiation gene expression of human periodontal ligament cells.

    Beijing Da Xue Xue Bao. 2013 Dec 18;45(6):975-8

    Authors: Ding Q, Zhang FQ, Ma YS

    Abstract
    OBJECTIVE: To observe the effect of icariin on human periodontal ligament cells (hPDLCs) differentiation to osteoblast gene expression.
    METHODS: The fifth generation of the cultured hPDLCs was added with the concentration of 0.01 mg/L icariin, and the added osteogenic medium used as blank control group, alizarin red staining of icariin on human periodontal ligament cells was observed for 21 days; the 2, 4, and 6 days of Q-PCR quantitative analysis of icariin on human periodontal ligament cells were made for osteogenesis gene alkaline phosphatase (ALP), type I collagen and osteocalcin (OC) gene expression.
    RESULTS: For the 21 days, alizarin red staining icariin group formed more mineralized nodules; on the 2nd, 4th, and 6th days, the group of icariin promoted the expression of ALP and OC mRNA, reached the peak value on day 6, compared with the control group with significant difference (20.15±6.67 vs. 7.90±0.71, 4.13±0.56 vs. 3.55±0.08, P<0.01). The second day, the highest expression of type I collagen appeared, then decreased gradually after, statistically compared with the control group (P<0.05).–CONCLUSION: Icariin can promote the human periodontal ligament cells differentiation to osteoblast, and promote the osteogenesis gene expression.–PMID: 24343085 [PubMed – indexed for MEDLINE]

    Recipe— Take a alcohol extract and apply direct on the gums or utilize as a mix to swish in the mouth

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    Whey to control diabetes

    Date:

    August 5, 2014

    Source:

    American Friends of Tel Aviv University

    Blood sugar surges — after-meal glucose “spikes” — can be life threatening for the 29 million Americans with diabetes. Diabetic blood sugar spikes have been linked to cardiovascular disease, cancer, Alzheimer’s disease, kidney failure, and retinal damage. Now a new Tel Aviv University study, published in Diabetologia, suggests a novel way to suppress these deadly post-meal glucose surges: the consumption of whey protein concentrate, found in the watery portion of milk separated from cheese curds, before breakfast.–According to TAU’s Prof. Daniela Jakubowicz and Dr. Julio Wainstein of the Wolfson Medical Center’s Diabetes Unit, Prof. Oren Froy of the Hebrew University of Jerusalem, and Prof. Bo Ahrén of Lund University in Sweden, the consumption of whey protein before meals may even keep diabetics’ need for insulin treatment at bay.–“What’s remarkable is that consuming whey protein before meals reduces the blood sugar spikes seen after meals. It also improves the body’s insulin response, putting it in the same range or even higher than that produced by novel anti-diabetic drugs,” said Prof. Jakubowicz. “High milk intake has long been associated with lower risk for type 2 diabetes and cardiovascular disease, and milk whey protein increases the production of a gut hormone called glucagon-like peptide-1 (GLP-1) that stimulates insulin secretion. This, in turn, reduces the blood glucose rise after meals.”-“We hypothesized that stimulating GLP-1 production by consuming whey protein before a meal would enhance insulin secretion and have beneficial glucose-lowering effects in type 2 diabetes,” Prof. Jakubowicz said.——–The study was conducted on 15 individuals with well-controlled type 2 diabetes at Wolfson Medical Center. The participants were randomized to receive either 50 grams of whey in 250 ml water or a placebo, followed by a standardized high-glycemic index breakfast of three slices of white bread and sugary jelly — a meal designed to produce the maximum post-meal glucose spike.—Blood samples were taken 30 minutes before the meal, when the whey protein or placebo drinks were consumed. Further blood samples, assessing plasma concentration of glucose, intact GLP-1, and insulin concentrations, were taken when the breakfast was served and at 15, 30, 60, 90, 120, 150, and 180 minute intervals after the meal.—–The researchers found that glucose levels were reduced by 28 percent after the whey pre-load over the 180-minute post-meal period, with a uniform reduction during early and late phasesWith whey pre-load, insulin and GLP-1 responses also were significantly higher (105 and 141 percent, respectively), producing a 96 percent increase in early insulin response.—“The early insulin response that usually is deficient in type-2 diabetes was significantly higher after whey protein than with placebo, and the whey protein preload significantly reduced the elevation of blood glucose after breakfast,” said Prof. Jakubowicz. “Whey protein could therefore represent a novel approach for enhancing glucose-lowering strategies in type 2 diabetes.”–Based on the findings of this study, the authors are considering a long-term clinical trial to test the enduring benefits of whey protein consumption for diabetics.–Story Source–The above story is based on materials provided by American Friends of Tel Aviv UniversityNote: Materials may be edited for content and length.–Journal Reference-Daniela Jakubowicz, Oren Froy, Bo Ahrén, Mona Boaz, Zohar Landau, Yosefa Bar-Dayan, Tali Ganz, Maayan Barnea, Julio Wainstein. Incretin, insulinotropic and glucose-lowering effects of whey protein pre-load in type 2 diabetes: a randomised clinical trialDiabetologia, 2014; 57 (9): 1807 DOI: 10.1007/s00125-014-3305-x

    Suggestion—When Buy a whey product there will be several—whey concentrate-whey isolate-whey hydroslate  —in this study the whey concentrate was used because of it is slower release and not used up as quickly—the isolates and hydroslates—are uptaken very easily and can e regulated with the use of fats—

    Never use any whey mixed with aceslfame-aspartame-neotame-artificial flavour-natural flavour-HFCS-Corn Sugar-SOY—-it should be a plain whey—with no additive—flavours can be real vanilla and real cocoa—or buy plain and add this to the smoothie or protein mix

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    Chili peppers for a healthy gut- Spicy chemical may inhibit gut tumors

    Date:

    August 1, 2014

    Source:

    University of California, San Diego Health Sciences

    Chili peppers.

    Credit: © Alexey Laputin / Fotolia

    Researchers at the University of California, San Diego School of Medicine report that dietary capsaicin — the active ingredient in chili peppers — produces chronic activation of a receptor on cells lining the intestines of mice, triggering a reaction that ultimately reduces the risk of colorectal tumors.–The findings are published in the August 1, 2014 issue of The Journal of Clinical Investigation.–The receptor or ion channel, called TRPV1, was originally discovered in sensory neurons, where it acts as a sentinel for heat, acidity and spicy chemicals in the environment. “These are all potentially harmful stimuli to cells,” said Eyal Raz, MD, professor of Medicine and senior author of the study. “Thus, TRPV1 was quickly described as a molecular ‘pain receptor.’ This can be considered to be its conventional function, which all takes place in the nervous system.”–But Raz and colleagues have found that TPRV1 is also expressed by epithelial cells of the intestines, where it is activated by epidermal growth factor receptor or EGFR. EGFR is an important driver of cell proliferation in the intestines, whose epithelial lining is replaced approximately every four to six days.—“A basic level of EGFR activity is required to maintain the normal cell turnover in the gut,” said Petrus de Jong, MD, first author of the study. “However, if EGFR signaling is left unrestrained, the risk of sporadic tumor development increases.”—The scientists discovered that TRPV1, once activated by the EGFR, initiates a direct negative feedback on the EGFR, dampening the latter to reduce the risk of unwanted growth and intestinal tumor development. They found that mice genetically modified to be TRPV1-deficient suffered higher-than-normal rates of intestinal tumor growths.–“These results showed us that epithelial TRPV1 normally works as a tumor suppressor in the intestines,” said de Jong. In addition, molecular studies of human colorectal cancer samples recently uncovered multiple mutations in the TRPV1 gene, though Raz noted that currently there is no direct evidence that TRPV1 deficiency is a risk factor for colorectal cancer in humans.–“A direct association between TRPV1 function and human colorectal cancer should be addressed in future clinical studies,” he said.–But if such proves to be the case, the current study suggests one potential remedy might be spicy capsaicin, which acts as an irritant in mammals, generating a burning sensation in contact with tissue. Capsaicin is already broadly used as an analgesic in topical ointments, where its properties as an irritant overwhelm nerves, rendering them unable to report pain for extended periods of time. It’s also the active ingredient in pepper spray.

    The researchers fed capsaicin to mice genetically prone to developing multiple tumors in the gastrointestinal tract. The treatment resulted in a reduced tumor burden and extended the lifespans of the mice by more than 30 percent. The treatment was even more effective when combined with celecoxib, a COX-2 non-steroidal anti-inflammatory drug already approved for treating some forms of arthritis and pain.—“Our data suggest that individuals at high risk of developing recurrent intestinal tumors may benefit from chronic TRPV1 activation,” said Raz. “We have provided proof-of-principle.”–Co-authors include Petrus R. de Jong, UCSD Department of Medicine and University Medical Center Utrecht, The Netherlands; Naoki Takahashi, UCSD Department of Medicine and Niigata University Graduate School of Medical and Dental Sciences, Japan; Alexandra R. Harris, Jihyung Lee, Samuel Bertin, James Jeffries, Michael Jung, Jen Duong, Amy I. Triano, Jongdae Lee, David S. Herdman, Hui Dong, Lars Eckmann and Maripat Corr, UCSD Department of Medicine; Yaron Niv, Rabin Medical Center and Tel Aviv University, Israel; Koji Taniguchi, UCSD Department of Medicine and Keio University School of Medicine, Japan; Chang-Whan Kim, UCSD Department of Medicine and Catholic University of Korea; Stephanie M Stanford and Nunzio Bottini, La Jolla Institute for Allergy and Immunology.—This research was supported, in part, by the Crohn’s and Colitis Foundation of America, the Prins Bernhard Cultural Foundation, the Scholten-Cordes Foundation, the Dr. Hendrick Muller Vaderlandsch Foundation, the Japan Society for the Promotion of Science, the European Molecular Biology Organization, the Juvenile Diabetes Research Foundation, the Strategic Young Researcher Overseas Visits Program for Accelerating Brain Circulation, the Broad Medical Foundation and the National Institutes of Health (grants AI095623 and DK35108).–Story Source-The above story is based on materials provided by University of California, San Diego Health SciencesNote: Materials may be edited for content and length.–Journal Reference–Petrus R. de Jong, Naoki Takahashi, Alexandra R. Harris, Jihyung Lee, Samuel Bertin, James Jeffries, Michael Jung, Jen Duong, Amy I. Triano, Jongdae Lee, Yaron Niv, David S. Herdman, Koji Taniguchi, Chang-Whan Kim, Hui Dong, Lars Eckmann, Stephanie M. Stanford, Nunzio Bottini, Maripat Corr, Eyal Raz. Ion channel TRPV1-dependent activation of PTP1B suppresses EGFR-associated intestinal tumorigenesisJournal of Clinical Investigation, 2014; DOI: 10.1172/JCI72340

    Suggestions

    utilize in foods—make a straight extract –using either water or alcohol,

    and apply it as a remedy straight usage  or add to foods

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    Cytotoxicity and Inflammatory Effect of Silver Nanoparticles

    in Human Cells

     

     

    Cytotoxicity and Inflammatory Effect

    of Silver Nanoparticles

    in Human Cells

    Jeong-shin Park, Na Mi Yu, Jinwoo Cheon and In-Hong Choi

    Department of Microbiology, College of Medicine;

    Department of Chemistry;

    Nanomedical NCRC, Yonsei University, Seoul, Korea

    1. Approaches to practical toxicology tests

    to assess nanoparticles

    1. Cytotoxicity and inflammatory effects

    of silver nanoparticles

    Nanoparticles and toxicity assay

     

    The rapidly developing field of nanotechnology will result

    in exposure of nanoparticles to humans via several routes

    (e.g., inhalation, ingestion, skin, etc.). Nanoparticles can

    translocate from the route of exposure to other vital

    organs and penetrate cells.

    • Toxicity studies to determine the deleterious effects of

    nanoparticles on living cells are required.

    • Due to the nanosize and the nature of agglomeration,

    simple standard methods to characterize the biological

    effects of nanoparticles are currently unavailable.

    • In this study, practical information regarding the optimalin

    vitro tests for nanotoxicity were evaluated.

    Silver nanoparticles

    03/19

    Antimicrobial applications

    Ink

    Cosmetics 200nm 200nm 500nm

    20 nm (synthetic)

    180 nm

    (commercial,

    Aldrich)

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