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    This is Health and the secrets of health

















    All DIS-EASES are Preventable
    Saturated Fats are NEEDED to Maintain good health

    With the right Ingredients your body could regenerate Indefinitely…example of this are oxygen and aminos in right proportions with the right fats and minimal sugars.. certain cells have been kept alive long after the death of an animal for over 30 years

    FASTING can and will save your life

    Mediterranean diets as well as Asian and Near east Asian diets are similar in that the diets are rich in antioxidants and preventatives that protect the body from toxins and poisons in the foods they eat (potential toxins)

    What is not being told to the western cultures is that Asians have 3-4 X’s higher accounts of cancer from Soy products then western women in the pancreas, esophagus, intestines, and thyroid

    Organic = Carbon Based…this applies to anything that is a carbohydrate ( veges, fruits, and grains) nothing states that it is chemical or pesticide free, or genetically free it is implied therefore you think it is safe

    Info of this has been known …since the dawn of time
    Antioxidants and other Body Cleaners are Key to a DIS-EASE Free Body

    The One thing in common with all cultures from anywhere in the world is to be clean internally and externally

    Pollutants and Chemicals are the key disasters to a dysfunctional immune system

    Foods laced with hormones and xeno-estrogens are causing havoc in your system

    SOY is not the wonder food that you think it is if anything it is a depletory of vital minerals that are needed to maintain the right bio-electric field needed and required for a health immune system as well as a proper running nervous system

    Multinationals in certain bio engineering areas of agriculture are not concerned about you or whether you eat ORGANIC or NONE Organic foods ( they are both essentially the same)

    Pesticides are ever being used whether intentionally or otherwise just by proximity to others who use them

    Alot here and there is more alot more.. did you know for about 2-3.00$ ‘s a day you can take a cancer preventative …..and you can get them at a grocery store.. Apples and Garlic eaten raw and peeled( yep peel the apples they are mostly imported nowadays and usually have some kind of spraying whether it’s acceptable or not and when coated with wax it seals the poisons til it enters your gut and then the oils mixed with chemicals gives your liver a problem not worth it….better to peel and eat them together makes for a good synergy


    My intent is to give any and all info I get or have attained over the years to everyone freely.. no charge no 1-900# nada if I do make any financial gain here it will be due to the fact that I will be in a consulting manner in either doing workshops or seminar or personal consulting in area of health or in making your own herbal combo’s …compounding your own supplements …or teaching you how to make your own tinctures creams, and how to get the most effective use out of the supplements you are already taking

    I will start ..with a workshop I did several weeks ago…THIS is what was covered…..

    Now I have to tell you…. this is all on your own ..and if you do have health issues seek a UNBIASED MD. who is not afraid or unopposed to practicing there Oath on health…or willing to explore in your best interest your complete Healing or maintaining a healthy life style…these are all suggestions based on what I have either personally have seen or EXPERIENCED and all I can do is share this info.. It’s up to you to know yourself and your limitations.. always always, in any new adventure take it slow and in low doses till you see an effect ( good or bad) and from there either maintain dose ( for only a period of time) or reduce it or stop completely


    Table of contents in Decending Order (bottom up)

    Curcumin could cut plaque build-up linked to Alzheimer’s…………………………………Page 180

    Curcumin linked to better performance for elderly brains ………………………………………Page 183


    Dark chocolate beats fatigue, study …….Page 179



    FDA Poisonous Plant Database  March 2006 Revision
    This database contains references to the scientific literature describing studies of the toxic properties and effects of plants and plant parts………Page 51


    The Secret World of Spices………………….PAGE 26


    Cardamon……………………………………..Page 25


    Thyme………………………………………….Page 13

    Pineapple……………………………………..Page 9


    Yogurt…………………………………………Page 6



    Wine is key to longer life, says new study…Page 3






    Health Prevention & Health Revitalization Workshop

    Why you should attend this “free” workshop?


    Health is on the mind of us all…. But how is one to determine which supplement remedy will work?

    Alternative health care books, are extraordinary confusing as well as contradictory….SO how is one to choose the right Doctors book?



    He challenges you to put on your thinking cap! Come listen and ask questions. You’ll be inspired to make lifestyle changes, because it will make sense and it will be simple for you



    Learn…How to use everyday spices and herbs as preventatives and cures…How to combine supplements and herbs for powerful results….how to use  Essential oils to prevent the body from getting sick…How to fight fungus with herbs, spices essential oils, and food…How to maintain and rejuvenate brain health…How to prevent cancer….how to make tinctures without using fillers or binders, inexpensively….Learn why you should avoid Soy Products, and Canola oil at all cost (FDA 288 page study about Soy products and Canola oil toxicity reports) Wonder why no one is sounding the alarm in the 15 billion dollar industry? Tony welcomes you to call him if you would like to add a category not mentioned above  602-795-2827  

    Tony’s dedication to research, years working in the health care field and “proven” techniques in herbalogy . . has given him a distinct advantage to helping people live healthier and successfully fight illnesses.  Pat states:  “The liver formula Tony recommended brought my enzymes within a normal range in one month!  My doctor was amazed as they were significantly higher.” 


    After being around Tony a short time. . you’ll know his enthusiasm to help you is genuine!   He truly cares about helping people. 









    ****Their will be remedies, colognes, CD’s and booklets and other items for purchase, Also Consultations by appointment *****




    ¯ Wine is key to longer life, says new study

    By staff reporter

    3/1/2007- More evidence that drinking moderate amounts of wine every day can increase life expectancy has been put forward by Dutch researchers.

    Around half a glass of wine per day was linked to a 48 per cent lower risk of heart disease in men, said the researchers, presenting their findings at the American Heart Association’s 47th annual conference.

    The same amount was also associated with a 40 per cent lower risk of death from all causes.

    Their research broadens existing health claims made about moderate red wine consumption to all wine, and to some extent, alcohol in general.

    The team analysed a lifestyle and dietary survey of 1,373 men from Zutphen, an industrial town in the eastern Netherlands. Known as the Zutphen Study, it followed the men, all born between 1900 and 1920, until death and measured their alcohol intake seven times over 40 years.

    Martinette Streppel, lead author of the new research, said the results were specific to “long-term, light alcohol intake among middle-aged men“.

    Wine gave the most protection when compared with other alcoholic drinks, adding an extra two years on to the drinker’s life on average, said Streppel, a PhD student at Wageningen University.

    And, men who drank small amounts of wine (around 45ml) could expect to live nearly four years longer than those who drank no alcohol.

    “Those people who already consume alcoholic beverages should do so lightly (1 to 2 glasses per day) and preferably drink wine,” said Streppel.

    Several previous studies have linked moderate consumption of red wine to lower heart disease risk and even longer life.

    More recently, these apparent benefits have been attributed to polyphenols in the wine, which are thought to provide strong protection for human blood vessels. One type of polyphenol in wine, procyanidins, are considered the most active.

    SourcePresentation to American Heart Association’s 47th Annual Conference on Cardiovascular Disease Epidemiology and Prevention.
    Authors: Martinette Streppel, Marga Ocke, Hendriek Boshuizen, Frans Kok and Daan Kromhout (all PhD).



    Yogurt is not just a delicious snack with fruits on the bottom, it has great health benefits. It is an excellent source of protein, calcium, riboflavin and vitamin B 12. When yogurt is compared to milk, yogurt contains more calcium and protein because of the added cultures in the yogurt.   Yogurt must contain active and living cultures to be yogurt. Cultures are composed of unique living microorganisms which are responsible for many of the health and nutritional benefits of yogurt. Some of the health benefits of yogurt are   It improves natural defense, it contains a good amount of phosphorus and 88% water. People with a risk of osteoporosis should eat at least one serving of yogurt per day.  It has also been claimed that yogurt may protect against some types of cancer but more investigations have to be carried out.  Some people have trouble digesting lactose, a carbohydrate in milk and milk products, because of the deficiency of enzyme lactase in the body. Live yogurt cultures produce lactase and break down the lactose. Yogurt is a healthy way to get the calcium the body needs, for the people who can not tolerate milk products. Other benefits of live and active cultures in the yogurt are, they may help to boost the immune system. They encourage the right kind of bacteria to multiply in the gut. These bacteria help to digest food and prevent stomach infectionsAlso, they help to provide relief from vaginal infections.

    Yogurt was a long-established staple in Eastern Europe and the Middle East before it reached our shores.

    Friendly Bacteria

    Yogurt may not be the miracle food some have claimed, but it certainly has a lot to offer in the health department. Besides being an excellent source of bone-building calcium, it is believed that the bacterial cultures Lactobacillus bulgaricus (L. bulgaricus) and Streptococcus thermophilus (S. thermophilus), that are used to make yogurt, carry their own health benefits.

    For example, research has suggested that eating yogurt regularly helps boost the body’s immune-system function, warding off colds and possibly even helping to fend off cancer. It is also thought the friendly bacteria found in many types of yogurt can help prevent and even remedy diarrhea.

    For people who suffer from lactose intolerance, yogurt is often well tolerated because live yogurt cultures produce lactase, making the lactose sugar in the yogurt easier to digest (see Lactose Intolerance for advice on coping with this condition). Be sure to check the label on the yogurt carton for the National Yogurt Association’s Live and Active Cultures (LAC) seal. This seal identifies products that contain a significant amount of live and active cultures

    In 2002, a Joint FAO/WHO Working Group defined probiotics as “live microorganisms which when administered in adequate amounts confer a health benefit on the host”. In other words, probiotics are live bacteria that are beneficial to our health, when eaten an adequate amount. It is important for our large intestine to maintain a healthy count of these “good” bacteria – a concept first promoted by a Russian scientist in 1907!

    Health Benefits of Probiotics

    • Studies found that probiotics may improve nutrient bioavailability, including B vitamins, calcium, iron, zinc, copper, magnesium and phosphorus.
    • Pediatric studies found that probiotics aids in a significantly decreasing the rate of acute diarrhea and rotavirus shedding. Parents also reported a 25% decrease in diaper rash among babies drinking formula containing probiotics.
    • Probiotics and active bacteria culture may improve lactose intolerance. The bacterial strain commonly used in yogurt can produce lactase enzymes. Therefore, people with lactose intolerance and children suffering from intestinal infection can usually tolerate yogurt with an active culture.
    • Many studies showed that by regulating intestinal transit time, probiotics improve constipation among the elderly.
    • Other studies showed that probiotics, especially acidophilus, promotes the growth of healthy bacteria in the colon and reduces the conversion of bile into carcinogens (cancer causing substances).
    • Quite a few studies found that probiotics may enhance immunity by regulating lymphocytes as well as antibodies


    Pineapple contains the protein digesting enzyme mixture called bromelain. The uses of these enzymes are similar to those mentioned in the notes on papaya. However, fresh pineapple juice has many other uses. When tuberculosis was common instead of the rarity it has now become, the juice was found to be effective in dissolving mucus and aiding recovery from the once dread disease.

    Pineapple has been thought good for heart conditions and indeed should not be used by people with haemophilia or by those with diseases of the kidneys and liver. This is because it seems to reduce the time taken to coagulate the blood – which is why it can be useful for heart patients.

    Sore throats and bronchitis are relieved by sipping the juice. Choose ripe fruits of good colour for pineapples do not become sweeter on storage if they are picked green. This is because the starch in the stem is taken up into the fruit and converted to sugar only at the final stage of ripening. If it is cut off beforehand then the sweetness can be as little as a half of that found in a ripe fruit allowed to finish its development on the plant


    ­­­Pineapple Strengthens Bones
    One of the benefits of pineapple is that it helps to build healthy bones. Pineapples are rich in manganese, a trace mineral that is needed for your body to build bone and connective tissues. Just one cup of pineapple provides 73% of the daily recommended amount of manganese. The benefits of pineapple can effect the growth of bones in young people and the strengthening of bones in older people


    Health Benefits

    ­A Digestive Aid and A Natural Anti-Inflammatory

    Fresh pineapple is rich in bromelain, a group of sulfur-containing proteolytic (protein-digesting) enzymes that not only aid digestion, but can effectively reduce inflammation and swelling, and has even been used experimentally as an anti-cancer agent. A variety of inflammatory agents are inhibited by the action of bromelain. In clinical human trials, bromelain has demonstrated signifcant anti-inflammatory effects, reducing swelling in inflammatory conditions such as acute sinusitis, sore throat, arthritis and gout, and speeding recovery from injuries and surgery. To maximize bromelain’s anti-inflammatory effects, pineapple should be eaten alone between meals or its enzymes will be used up digesting food. Bromelain is found in both the flesh and stem of pineapple. Since it is deactivated by heat, pineapple juice and canned pineapple are not good sources of this health-promoting enzyme. In terms of getting bromelain from pineapple, fresh is definitely the way to go.

    ­Antioxidant Protection and Immune Support

    Vitamin C is the body’s primary water-soluble antioxidant, defending all aqueous areas of the body against free radicals that attack and damage normal cells. Free radicals have been shown to promote the artery plaque build-up of atherosclerosis and diabetic heart disease, cause the airway spasm that leads to asthma attacks, damage the cells of the colon so they become colon cancer cells, and contribute to the joint pain and disability seen in osteoarthritis and rheumatoid arthritis. This would explain why diets rich in vitamin C have been shown to be useful for preventing or reducing the severity of all of these conditions. In addition, vitamin C is vital for the proper function of the immune system, making it a nutrient to turn to for the prevention of recurrent ear infections, colds, and flu.

    ­Manganese and Thiamin (Vitamin B1) for Energy Production and Antioxidant Defenses

    Pineapple is an excellent source the trace mineral manganese, which is an essential cofactor in a number of enzymes important in energy production and antioxidant defenses. For example, the key oxidative enzyme superoxide dismutase, which disarms free radicals produced within the mitochondria (the energy production factories within our cells), requires manganese. Just one cup of fresh pineapple supplies 128.0% of the DV for this very important trace mineral. In addition to manganese, pineapple is a good source of thiamin, a B vitamin that acts as a cofactor in enzymatic reactions central to energy production.

    ­Anti-Tumor Compounds Found in Pineapple Stems

    Two molecules found in pineapple stems have shown anti-tumor activity in research done at Australia’s Queensland Institute of Medical Research (QIMR). One of the molecules, called CCS, blocks the Ras protein, which is defective in approximately 30% of all cancers, while the other molecule, CCZ, stimulates the immune system to target and eliminate cancer cells.

    The QIMR researchers discovered these anti-cancer molecules while studying bromelain. “We suspected that different components of the crude mixture might be responsible for bromelain’s biological effects. In searching for these components, we discovered the CCS and CCZ proteins and found that they could block growth of a broad range of tumour cells, including breast, lung, colon, ovarian and melanoma,” said lead researcher, Dr. Tracey Mynott.

    The major limitation of current cancer therapies is they are non-specific and affect both normal and tumor cells. Future cancer treatments will be highly specific to selectively destroy the cancer cells, counteracting the mechanisms by which cancers grow. Data already generated show that CCS and CCZ have the desired specificity and selectivity.

    “An interesting characteristic of CCS and CCZ is that they are proteases. Proteases are traditionally thought of as degradative enzymes which breakdown proteins, such as in the process of digestion. Other reports on the role of proteases in disease have centered on their potential to cause damage. CCS and CCZ are the first examples of proteases that have been shown to modulate cell signal transduction pathways and have specific immunomodulatory activities,” said Dr Mynott.

    “The way CCS and CCZ work is different to any other drug in clinical use today. Therefore, CCS and CCZ will represent a totally new way of treating disease and potentially a whole new class of anti-cancer agent. In general, products with novel mechanisms of action are more likely to represent real breakthroughs in the treatment or prevention of disease.” QIMR is continuing to investigate CCS and CCZ to demonstrate i) additional in vivo proof of principle, ii) reliable supply of the material and iii) safety. All these factors will be addressed in a two year research program. If all the objectives of the research are achieved, CCS or CCZ will rapidly progress to human clinical trials.

    ­Protection against Macular Degeneration

    Your mother may have told you carrots would keep your eyes bright as a child, but as an adult, it looks like fruit is even more important for keeping your sight. Data reported in a study published in the Archives of Ophthalmology indicates that eating 3 or more servings of fruit per day may lower your risk of age-related macular degeneration (ARMD), the primary cause of vision loss in older adults, by 36%, compared to persons who consume less than 1.5 servings of fruit daily.

    In this study, which involved over 110,000 women and men, researchers evaluated the effect of study participants’ consumption of fruits; vegetables; the antioxidant vitamins A, C, and E; and carotenoids on the development of early ARMD or neovascular ARMD, a more severe form of the illness associated with vision loss. While, surprisingly, intakes of vegetables, antioxidant vitamins and carotenoids were not strongly related to incidence of either form of ARMD, fruit intake was definitely protective against the severe form of this vision-destroying disease. Three servings of fruit may sound like a lot to eat each day, but pineapple can help you reach this goal. Add fresh pineapple to your morning smoothie, lunch time yogurt, any fruit and most vegetable salads. For example, try adding chunks of pineapple to your next coleslaw or carrot salad.



    Antimicrobial activity of Thyme
    The extracts from thyme by water and ethanol, thyme essential oil, thymol and carvacrol were used as antimicrobial agents. The results show that all antimicrobial agents used have strong inhibition activity against Staphalococcus aureus, Bacillus subtilis, and Escherichia coli.

    Thyme Research Update
    Systemic availability and pharmacokinetics of thymol in humans.

    J Clin Pharmacol. 2002 Jul;42(7):731-7.
    Essential oil compounds such as found in thyme extract are established for the therapy of chronic and acute bronchitis. Various pharmacodynamic activities for thyme extract and the essential thyme oil, respectively, have been demonstrated in vitro, but availability of these compounds in the respective target organs has not been proven. Thus, investigation of absorption, distribution, metabolism, and excretion are necessary to provide the link between in vitro effects and in vivo studies. To determine the systemic availability and the pharmacokinetics of thymol after oral application to humans, a clinical trial was carried out in 12 healthy volunteers. Each subject received a single dose of a Bronchipret TP tablet, which is equivalent to 1.08 mg thymol. No thymol could be detected in plasma or urine. However, the metabolites thymol sulfate and thymol glucuronide were found in urine. Thymol sulfate, but not thymol glucuronide, was detectable in plasma. Peak plasma concentrations were reached after 2.0 hours. The mean terminal elimination half-life was 10 hours. Thymol sulfate was detectable up to 41 hours after administration. Urinary excretion could be followed over 24 hours. The amount of both thymol sulfate and glucuronide excreted in 24-hour urine was 16% of the dose.

    In-vitro anti-inflammatory effect of Eucalyptus globulus and Thymus vulgaris: nitric oxide inhibition in J774A.1 murine macrophages.
    J Pharm Pharmacol. 2004 Feb;56(2):257-63.
    It is well known that nitric oxide (NO) plays an important role in the pathogenesis of inflammatory diseases. Eucalyptus globulus Labill. and Thymus vulgaris L. ( thyme ) have been used in traditional medicine in the treatment of bronchitis, asthma and other respiratory diseases. The present study focuses on the effects of these two extracts on NO production induced by lipopolysaccharide and interferon-gamma (IFN-gamma) in the murine macrophage cell line. E. globulus and thyme extracts significantly inhibited the enhanced production of NO induced by LPS and IFN-gamma in a dose-dependent manner. Treatment with these two extracts did not reduce cell viability at any dose used. Both eucalyptus and thyme showed significant scavenging of NO radicals released by an NO donor, PAPA-NONOate. Results also show that pre-treatment with E. globulus and thyme extracts significantly inhibits iNOS mRNA expression. This study thus suggests that the inhibition of net NO production by these two extracts may be due to their NO scavenging activity and/or their inhibitory effects on iNOS gene expression.

    Human platelet aggregation inhibitors from thyme (Thymus vulgaris L.).
    Phytother Res. 2002 Jun;16(4):398-9.
    Two antiaggregant compounds, thymol (compound 1) and 3,4,3′,4′-tetrahydroxy-5,5′-diisopropyl-2,2′-dimethylbiphenyl (compound 2) were isolated from the leaves of thyme. These compounds inhibited platelet aggregation induced by collagen, ADP, arachidonic acid and thrombin except that compound 2 did not inhibit platelet aggregation induced by thrombin. thyme maternity rosemary and thyme herbs thyme wild thyme parsley sage rosemary and thyme oil thyme.

    Effect of thyme oil and thymol dietary supplementation on the antioxidant status and fatty acid composition of the ageing rat brain. thyme plant
    Aromatic and Medicinal Plant Group, Scottish Agricultural College, Auchincruive, Ayr, UK.
    Br J Nutr. 2000 Jan;83(1):87-93.
    The present study measured changes in antioxidant enzyme activity in, and the phospholipid fatty acid composition of the ageing rat brain and tested whether dietary supplementation with thyme oil or thymol could provide beneficial effects. There were significant declines in superoxide dismutase (EC and glutathione peroxidase (EC activities and the total antioxidant status in the untreated rats with age, while thyme-oil- and thymol-fed rats maintained significantly higher antioxidant enzyme activities and total antioxidant status. The proportions of 18:2n-6, 20:1n-9, 22:4n-6 and 22:5n-3 in the brain phospholipids resulting from all three dietary treatments were significantly higher in 28-month-old rats than in 7-month-old rats. Only 20:1n-9 levels in 28-month-old thyme-oil- and thymol-treated rats were significantly higher than in the age-matched control. The proportion of 22:6n-3 in brain phospholipids, which declined with age in control rats, was also significantly higher in rats given either supplement. This latter finding is particularly important as optimum levels of 22:6n-3 are required for normal brain function. These results highlight the potential benefit of thyme oil as a dietary antioxidant. thyme research thyme oil. season of thyme wild mountain thyme thyme picture thyme and again
    classic thyme olive thyme cookware old thyme herb olive thyme tea thyme.



    Relieves nightmares, strengthens breathing, strengthens weak stomach, gas, cramps, diarrhea, relieves headaches.

    Thyme is a cultivated form of the wild thyme of the mountains European countries bordering the Mediterranean. Thyme contains very high concentrations of antioxidants (i.e., >75 mmol/100 g). In a normal diet, intake of herbs may therefore contribute significantly to the total intake of plant antioxidants, and be an even better source of dietary antioxidants than many other food groups such as fruits, berries, cereals and vegetables.

    Health Benefits

    Thyme has a long history of use in natural medicine in connection with chest and respiratory problems including coughs, bronchitis, and chest congestion. Only recently, however, have researchers pinpointed some of the components in thyme that bring about its healing effects. The volatile oil components of thyme are now known to include carvacolo, borneol, geraniol, but most importantly, thymol.

    Significant Anti-Oxidant Protection of Cellular Membranes

    Thymol – named after the herb itself – is the primary volatile oil constituent of thyme, and its health-supporting effects are well documented. In studies on aging in rats, thymol has been found to protect and significantly increase the percentage of healthy fats found in cell membranes and other cell structures. In particular, the amount of DHA (docosahexaenoic acid, an omega-3 fatty acid) in brain, kidney, and heart cell membranes was increased after dietary supplementation with thyme. In other studies looking more closely at changes in the brains cells themselves, researchers found that the maximum benefits of thyme occurred when the food was introduced very early in the lifecycle of the rats, but was less effective in offsetting the problems in brain cell aging when introduced late in the aging process. Thyme also contains a variety of flavonoids, including apigenin, naringenin, luteolin, and thymonin. These flavonoids increase thyme’s antioxidant capacity, and combined with its status as a very good source of manganese, give thyme a high standing on the list of anti-oxidant foods.


    Eradicate Microbes with Thyme

    The volatile oil components of thyme have also been shown to have antimicrobial activity against a host of different bacteria and fungi. Staphylococcus aureus, Bacillus subtilis, Escherichia coli and Shigella sonnei are a few of the species against which thyme has been shown to have antibacterial activity.

    For thousands of years, herbs and spices have been used to help preserve foods and protect them from microbial contamination, now research shows that both thyme and basil contain constituents that can both prevent contamination and decontaminate previously contaminated foods. In these studies, published in the February 2004 issue of Food Microbiology, researchers found that thyme essential oil was able to decontaminate lettuce inoculated with Shigella, an infectious organism that triggers diarrhea and may cause significant intestinal damage. In addition, washing produce in solution containing either basil or thyme essential oil at the very low concentration of just 1% resulted in dropping the number of Shigella bacteria below the point at which they could be detected. While scientists use this research to try to develop natural food preservatives, it makes good sense to include thyme and basil in more of your recipes, particularly for foods that are not cooked such as salads. Adding fresh thyme and/or basil to your next vinaigrette will not only enhance the flavor of your fresh greens, but will help ensure that the fresh produce you consume is safe to eat.

    A Nutrient-Dense Spice

    The range of other health-supportive nutrients found in thyme is also impressive. This food emerged from our food ranking system as an excellent source of iron and manganese, a very good source of calcium and a food source of dietary fiber.


    A delicate looking herb with a penetrating fragrance, thyme is an herb we should all take time to investigate and enjoy. And with about sixty different varieties including French (common) thyme, lemon thyme, orange thyme and silver thyme, this herb is sure to add some spice to your life. Thyme leaves are curled, elliptically shaped and very small, measuring about one-eighth of an inch long and one-sixteenth of an inch wide. The upper leaf is green-grey in color on top, while the underside is a whitish color. French thyme is known scientifically as Thymus vulgaris.


    Thymus vulgaris


    Names: Common Thyme, Garden Thyme

    Habitat: Thyme is indigenous to the Mediterranean region, and cultivated widely.

    Collection: The flowering branches should be collected between June and August on a dry sunny day. The leaves are stripped off the dried branches.

    Part Used: Leaves and flowering tops.


    • Volatile oil, of highly variable composition; the major constituent is thymol, with
    • lesser amounts of carvacrol, with 1, 8-cineole, borneol, geraniol, linalool, bornyl and
    • linalyl acetate, thymol methyl etherand [[alpha]]-pinene.
    • Flavonoids; apigenin, luteolin, thymonin, naringenin and others
    • Miscellaneous; labiatic acid, caffeic acid, tannins etc.

    Actions: Carminative, anti-microbial, anti-spasmodic, expectorant, astringent, anthelmintic.

    Indications: With its high content of volatile oil, Thyme makes a good carminative for use in dyspepsia and sluggish digestion. This oil is also a strongly antiseptic substance, which explains many of Thyme’s uses. It can be used externally as a lotion for infected wounds, but also internally for respiratory and digestive infections. It may be use as a gargle in laryngitis and tonsillitis, easing sore throats and soothing irritable coughs. It is an excellent cough remedy, producing expectoration and reducing unnecessary spasm. It may be used in bronchitis, whooping cough and asthma. As a gentle astringent it has found use in childhood diarrhea and bed wetting.

    Kings’ Dispensatory describes it thus: “Thyme is tonic, carminative emmenagogue and anti-spasmodic. The cold infusion is useful in dyspepsia, with weak and irritable stomach and as a stimulating tonic in convalescence from exhausting diseases. The warm infusion is beneficial in hysteria, dysmenorrhea, flatulence, colic, headache, and to promote perspiration. Occasionally the leaves have been used externally, in fomentation. The oil is valuable as a local application to neuralgic and rheumatic pains; and, internally, to fulfill any of the indications for which the plant is used. Dose of the infusion, from 1 to 3 fluid ounces; of the oil, from 2 to 10 drops on sugar, or in emulsion. Thyme, skullcap and rue of each 2 ounces; peony and black cohosh, of each, 1 ounce; macerated for 14 days in diluted alcohol, and then filtered, forms a good preparation for nervous and spasmodic diseases of children. It may be given in teaspoonful doses to a child 3 years old, repeating it 3 or 4 times a day, sweetening and diluting it, if desired. A strong infusion of the Thymusserpyllus, slightly sweetened and mixed with gum Arabic, is stated by M. Joset to be a valuable remedy for whooping-cough, convulsive and catarrhal coughs and stridulous sore throat, the favorable result occurring at the end of a very few days. It may be taken ad libitum.”

    Combinations: For asthmatic problems it will combine well with Lobelia and Ephedra, adding its anti-microbial effect. For whooping cough use it with Wild Cherry and Sundew.

    Preparations & Dosage: Infusion: pour a cup of boiling water onto 2 teaspoonfuls of the dried herb and let infuse for 10 minutes. This should be drunk three times a day. Tincture: take 2-4ml of the tincture three times a day.


    Key constituents of thyme include thymol, carvacrol and flavonoids, often attributed with the antibacterial, antiflatulent and antiworming properties of the herb. Thyme is also used to suppress coughing, ease chest congestion and stimulate production of saliva (1).

    Thymol is considered to be antihelmintic (antiworm) with particular effectiveness against hookworm, and together with carvacrol is both antibacterial and antifungal (1) (2) (3).

    The German Commission E Monographs list thyme as being bronchoantispasmodic, expectorant and antibacterial (4).

    Traditionally it is the thyme leaf and flowering tops that have been used therapeutically. In folk medicine thyme is used to stimulate the appetite, suppress coughing, and relieve digestive disorders such as chronic gastritis, diarrhoea in children and flatulence. It is also used to expel parasitic worms (1) (2) (5), particularly in children (6).

    The overall antiseptic and tonic properties of thyme suit it well as a general boost for the immune system during times of chronic infection, and is still commonly used to remedy respiratory ailments (6).

    Laboratory studies demonstrate that thymol has antifungal activity against a number of species, including Cryptococcus neoformans, Aspergillus, Saprolegnia, and Zygorhynchus species. Further studies confirm the antibacterial actions of this constituent, with demonstrated activity against Salmonella typhimurium, Staphylococcus aureas, Escherichia coli and other bacterial species (7). As an antibiotic, thymol is 25 times as effective as phenol, but less toxic (7) (8) (9).

    Research in Scotland during the 1990’s suggests that thyme and its volatile oil may counter the effects of aging. Subsequent studies have confirmed thyme’s antioxidant properties, and how it helps the body maintain higher levels of essential fatty acids within the brain (6).

    Thyme is generally regarded as safe when used in normal amounts, and has a Generally Recognized as Safe (GRAS) status in the US. Typical dosages of thyme include up to 4 grams of dried herb equivalent three times per day (1) (10).

    Due to the lack of reliable information regarding large amounts of Thyme it should be limited to a moderate intake, particularly during pregnancy and breastfeeding (1).

    Mechanism of Action
    Key constituents of thyme include phenols (thymol, carvacrol), flavonoids, borneol, linalool, rosmarinic acid, saponins, tannins, terpenoids, and acetophenone glycosides.

    Thyme and thymol have shown antibacterial activity in vitro against Salmonella typhimurium, Staphylococcus aureus, Heliobacter pylori, Porphyromonas gingivalis, Selenomonas artemidis,Streptococcus sobrinus, and Streptococcus mutans. This activity is possibly related to cell membrane perforation. Thymol has also demonstrated antifungal activity against Candida albicans, Aspergillus parasiticus, and Aspergillus flavous.

    In vitro and in vivo studies show that thyme flavonoids relax tracheal and ileal smooth muscles. The mechanism of action may be inhibition of acetylcholine and histamine receptors, calcium channel antagonism, or inhibition of phasic contractions. This antispasmolytic activity may be dependent on flavone aglycone concentrations.

    In vitro and in vivo studies of thyme have also demonstrated antioxidant effects and anti-inflammatory effects including inhibition of prostaglandin synthesis. There are few studies on pharmacodynamic effects of thyme or thyme constituents. One study of the thyme phenolic constituents thymol and carvacrol showed rapid urinary excretion of metabolites.


    Culpeper states that thyme is:

    “a noble strengthener of the lungs, as notable a one as grows, nor is there a better remedy growing for hooping cough. It purgeth the body of phlegm and is an excellent remedy for shortness of breath. It is so harmless you need not fear the use of it. An ointment made of it takes away hot swellings and warts, helps the sciatica and dullness of sight and takes away any pains and hardness of the spleen: It is excellent for those that are troubled with the gout and the herb taken anyway inwardly is of great comfort to the stomach.”

    John Gerard maintains it will “cure sciatica and pains in the head” and is “healing in leprosy and the falling sickness,” and in the Middle Ages it was prescribed as a cure for nightmares.

    Camphor of thyme was noticed first by Neumann, apothecary to the Court at Berlin in 1725. It was called thymol and carefully examined in 1853 by Lallemand and recommended instead of phenol (carbolic acid) in 1868 by Bouilhon, apothecary, and Paquet, M.D., of Lille.

    Bees’ affinity for thyme is well known. Thyme honey, made when bees collect pollen from thyme flowers, is renowned. The fine flavor of the honey of Mount Hymettus near Athens was said to be due to the wild thyme with which it was covered, being of such special flavor and sweetness that in the minds and writings of the Ancients, sweetness and thyme were inextricably linked. “The honey which comes from thyme is held to be the best and most profitable,” wrote Pliny


    Inhibition of listeriolysin O and phosphatidylcholine-specific production in Listeria monocytogenes by subinhibitory concentrations of plant essential oils


    *Department of Dietetics, Nutrition and Biological Sciences, Queen Margaret University College, Clerwood Terrace, Edinburgh EH12 8TS and Department of Medical Microbiology, University of Edinburgh Medical School, Teviot Place, Edinburgh EH8 9AG

    Corresponding author: Dr L. Fyfe. *Present address: Department of Biological Sciences, Heriot-Watt University, Riccarton, Edinburgh EH14 4AS.

    Received 15 March 2001; revised version accepted 22 Oct. 2001.


    Successful infection by Listeria monocytogenes is dependent upon a range of bacterial extracellular proteins including a cytolysin termed listeriolysin O and phosphatidylcholine-specific phospholipase C. Five plant essential oils – bay, clove, cinnamon, nutmeg and thyme – significantly reduced the production of listeriolysin O by L. monocytogenes. The greatest change was observed after culture with oil of thyme, which reduced haemolysis to 52.1 haemolytic units (HU)/ml compared with 99.85muHU/ml observed with the control. Oil of clove was the only oil that also significantly reduced phosphatidylcholine-specific phospholipase C activity. These changes were observed despite the oils causing no change to the final bacterial concentration or total extracellular protein concentration.





    Detoxifies the body of caffeine

    Cleanses kidneys and bladder

    Stimulates digestive system and reduces gas

    Expectorant action

     Improves circulation to the lungs and thus

    considered good for asthma and bronchitis


    Can counteract excess acidity in the stomach

    Stimulates appetite

    Remedy for tendency to infection

    Cures halitosi

    Cardamom is used for the following

    Elletaria cardamomum benefits:

    • colic
    • bedwetting
    • freshening the breath after eating garlic
    • kidneys and bladder
    • detoxifies caffeine
    • fighting infections
    • anorexia
    • asthma
    • digestion
    • antispasmodic

    Cardamon Seed Powder

    The seeds contain volatile oil, fixed oil, salt of potassium, a colouring principle, starch, nitrogenous mucilage, ligneous fibre, an acrid resin, and ash. The volatile oil contains terpenes, terpineol and cineol. —Medicinal Action and Uses—Carminative, stimulant, aromatic, but rarely used alone; chiefly useful as an adjuvant or corrective. The seeds are helpful in indigestion and flatulence, giving grateful but not fiery warmth. When chewed singly in the mouth the flavor is not unpleasant, and they are said to be good for colic and disorders of the head.

    CARDAMOM:  Strengthens the heart and lungs. It relieves pain, gas and sharpens the mind.

    Cardamom: Like ginger, cardamom is often used to soothe digestion problems. But it is also used to treat respiratory problems such as asthma or people suffering from other kinds of respiratory spasms. Further, in Saudi Arabia, animal studies have shown cardamom to have anti-inflammatory properties, reducing muscle spasms.

    The Secret World of Spices

    August 1999 — Cover Story

    By: Ronald C. Deis, Ph.D.
    Contributing Editor

      Spices do much more than impart flavor. In fact, a “secret” spice world has flourished for centuries, and is still cultivated by many cultures and modern-day herbalists. Spices and herbs have also been used for centuries as preservatives, colorants and medicinal remedies.

      China, India, Greece, Rome and Egypt have a rich history in the medicinal use of spices and herbs. Since the time of the ancient Greeks and Romans, spices have been used to combat snakebites, poor eyesight, stomach disorders, sleeping problems, poor circulation, sores, colds, muscular aches, gout, lumbago, poor digestion, motion sickness and hangovers. The apothecary industry in Europe emerged from the practice of blending spices and herbs to cure specific ills. In Middle-Age Europe, pomanders containing spice blends were popular as air purifiers, and were worn about the neck or hung in a room. Today, we might consider this potpourri.

      Spices have played an even larger role in history, however. The search for new and lower-cost spices resulted in the discovery of new lands and trade routes. Exploration needed a bottom line, and since spices were highly valued, any exploration that led to a new source or new spice filled the bill.

    What is a spice?

      According to the American Spice Trade Association (ASTA), Englewood Cliffs, NJ, ( the proper definition of spices, as opposed to herbs or botanicals, is “any dried plant product used primarily for seasoning purposes.” This definition includes a wide range of plants – tropical aromatics, leafy herbs, spice seeds, roots, dehydrated vegetables and spice blends.

      In the past, the leaves and seeds of temperate-zone plants were known as herbs, while the term spice denoted tropical aromatics only. Over time, this classification shifted, so that in general, the term spice now covers a whole range of elements – spices, herbs, blends and dehydrated vegetables. The FDA’s definition of spices, however, does not include dehydrated vegetables, so these require separate labeling in a product, as do any color-contributing spices such as paprika, turmeric or saffron. The USDA has much the same rules as the FDA, but also requires that onion and garlic be listed as “flavors.”

      Prior to the early 1800s, spices were available in whole form only, and it was up to the user to grind them. Today, we have whole spices, ground spices, seasoning blends, which may be a combination of several spices and several forms, and spice extractives. Spice extractives include essential oils (volatile aromatic fractions); oleoresins (derived by solvent extraction of the whole spice, including volatile and non-volatile fractions); liquid solubles (oleoresins plus solubilizing agents to create a liquid seasoning); dry solubles (oleoresins plated on a dry carrier); encapsulated spices; standardized oleoresins; and WONFs (essential oils plus other natural flavoring materials).

    Battling microbes

      Even in Middle-Age Europe, it was well-known that spices provide important preservation qualities. Salting, smoking, or pickling were also used to inhibit spoilage, but spices were preferred, which was the reason for their considerable worth.

      The most effective antimicrobial spices include garlic, onion, cinnamon, cloves, thyme and sage. Cloves, which have a high essential oil content, contain eugenol, a phenylpropanoid also present in sage and cinnamon. Allicin, present in garlic, also acts as an antimicrobial agent, as does the allyl isothiocyanate present in mustard. Thymol, present in thyme, oregano and sage, is also noted for its antimicrobial properties.

      Research at Kansas State University, Manhattan, has shown that cloves have a high antimicrobial effect against Escherichia coli 0157:H7 in ground meat. Cinnamon, garlic, oregano and sage were also shown to be effective – adding 7.5% garlic and clove killed 99% of the pathogen. This percentage is a little high for palatability, but further research could lead to extractives that are effective against specific bacteria.

      The best summary of what is known to date on the effectiveness of spices as antimicrobials is found in this list, adapted from L. Zaika in the Journal of Food Safety, 1988:

    • Microorganisms differ in their resistance to a given spice or herb.
    • A given microorganism differs in its resistance to various spices and herbs.
    • Bacteria are more resistant than fungi.
    • The effect on spores may be different than on vegetative cells.
    • Gram-negative bacteria are more resistant than gram-positive bacteria.
    • The effect may be inhibitory or germicidal (generally inhibitory).
    • HAACP is still important – spices and herbs may harbor contaminants or serve as substrate for growth.
    • Amounts of spices and herbs added to foods are generally too low to prevent spoilage.
    • Nutrients present in spices and herbs may actually stimulate microbial growth.
    • Active components may interact synergistically with other factors to increase preservative effect.

      The final item refers to an effect that has been recognized for some time and is often termed the “hurdle theory.” Microorganisms can be controlled through a combination of factors, including water activity, acidity, atmosphere (aerobic/anaerobic), temperature and chemical composition. For best antimicrobial results, adjustment should be made to as many of these factors as possible, throwing a number of “hurdles” in the way of microbial growth. If a number of factors can be combined so that the preservative effects of each can be realized without impacting the sensory attributes of the food product, the project is a success. If the preservative also brings along a desirable color or antioxidant effect, so much the better.

    Antioxidant activity

      Spices can also extend shelf life by slowing oxidation. In foods, lipid oxidation, protein oxidation, and enzymatic oxidation cause shelf-life problems. Rancidity development is an oxidative process that can be blocked by antioxidants, which block formation of free radicals by donating electrons or hydrogen ions to halt the oxidative process. While phenolic compounds such as butylated hydroxyanisole (BHA), butylated hydroxytoluene (BHT), or tertiary butylhydroquinone (TBHQ) are all very effective, economical ingredients, they are not appropriate for a natural product. On the other hand, commercial rosemary products might be a better fit. Active compounds in this herb are diphenolic diterpenes, which are highly effective antioxidants. The main constituents include: carnosol, carnosoic acid and its esters, and lesser amounts of rosmanol, rosmaridiphenol and rosmarinic acid. Sage and thyme also contain natural antioxidative compounds.

      The positive effects of antioxidants aren’t just limited to food preservation. In the body, free radicals are initiated by a number of processes – heat, UV light, radiation, alcohol and tobacco, for example. Free-radical damage to cells can limit the ability of cells to fight cancer or to limit aging. At the University of Kentucky, researchers found that Vitamin E, a strong antioxidant, can limit the death of brain cells exposed to a free-radical-stimulating protein in the brains of Alzheimer’s patients. Also, tests conducted by the USDA Tufts University in Boston, and Johns Hopkins University in Baltimore have demonstrated a link between heart disease and lipid oxidation. Spices might also provide some of the same effects.

    Compound Chemistry

    What are some of the chemical constituents responsible for the healing and preservative properties of spices and herbs? Several classes of compounds stand out, and have collectively been given the name “phytochemicals.” These are generally secondary metabolites produced by a plant as an attractant for insects or as a defense against microbial or animal attack. In our diet, these compounds can, taken in moderation with proper exercise and reduction of stress, act as one step toward improving the quality of life.

    Sulfur Compounds:
    Sulfides and thioles play a prominent role in the preservative features of the onion family, Alliaceae.

    Terpenes and Terpene Derivatives:
    Terpenes are divided into classes of molecular weight – monoterpenes have 10 carbon atoms; sesquiterpenes, 15; diterpenes, 20; and triterpenes, 30. Monoterpenes are the most common, and spices are differentiated by their specific mixture of these. Monoterpenes play a large role in the mint and parsley families. Common to this class are limonene, pinene, camphene, myrcene, dipentene, terpinene. The sesqui-, di-, and tri- terpenes are less common, and are usually found specific to certain families. Sesquiterpenes are important to the characteristics of cinnamon and the Zingiberaceae family (ginger, turmeric, galangal). Common to this class are farnesol and chamazulene. Di- and triterpenes are very bitter, and are responsible for some of the bitterness of the mint family. Carotenoids are terpene derivatives, as is thymol, a preservative compound of thyme.

    Phenols figure prominently in a number of products – eugenol in cloves, safrol in nutmeg, vanillin in vanilla beans, and cinnamic acid in cinnamon, for example. Others include thymol, anethole and myristicin.

    Glycosides are made up of two distinct parts – a sugar molecule, and a non-sugar part called an aglycon. The glycoside itself is usually non-volatile, but the aglycon is easily cleaved, and can be volatile. The best example of this type of compound is mustard-oil glycosides, which release an isothiocyanate that causes tears and burning, as from horseradish.

    The aldehyde groups includes citral, cinnamic aldehyde, benzaldehyde and citronellal.

    Esters are found in most essential oils, and include eugenyl acetate, bornyl acetate and linalyl acetate.

    Alcohols have notable antimicrobial and antiviral properties, and include farnesol, citronellol, linalool, methol, terpinol and benzyl alcohol.

      A series of papers presented by Wang, et. al., of the food science department at Rutgers University, New Brunswick, NJ, shows that a number of spices, most notably basil, rosemary and sage, are very active anti-tumorigenic agents. Another paper by Wang, et. al. discusses the antioxidant, antiviral, antibacterial, and antimicrobial activity of Dalmatian sage, Salvia officinalis. Of 25 compounds isolated from sage by alcohol extraction, four were found to be very active. Flavonoid compounds were also evaluated in ethyl extracts from rosemary; six compounds were identified. Evidence suggests that the presence of flavonoids and di- and triterpenes is responsible for the antioxidant properties of rosemary.

    Color combinations

      Spices also improve the appearance of a food. For example, at 4% to 16% carotenoids, chili peppers provide a range of red to green colors.

      Paprika, turmeric and their oleoresins, as well as saffron, are approved in the United States as color additives in 21 CFR section 73, and may be used with no restrictions.

      Saffron, produced from the stigma of Crocus sativas, a member of the iris family, has a very intense water-soluble, yellow-orange color. This color is caused by carotenoids, particularly crocetin and crocin, as well as P- and L-carotene, lycopene and zeazanthin. Saffron may be unique in its color and fragrance, but it is also the most expensive spice in the world, at a cost of over $300 per lb. Saffron is permitted as a natural color in the United States, but economics limits its use. Safflower, Carthamus tinctorius, is a frequent saffron substitute overseas, but is not permitted in this country. This member of the sunflower family owes its orange-red color to the flavanoid carthamin. Safflower oil, even better known as an ingredient, is a highly unsaturated oil with high vitamin E content.

      Turmeric, Curcuma longa, a member of the ginger family, is also a very effective natural colorant. The name Curcuma is actually derived from the Persian word “kirkum,” meaning saffron. When the roots of this plant are dried and ground, the powder produced is yellow with an orange tinge. The powder is often blended with paprika and annatto to produce the desired color. Its largest use is in prepared mustard, but it is also widely used in curry powder, pickles, relish, sausage and cheese. The extractable color in turmeric comes from curcumin, which is also a natural antioxidant.

      Paprika provides a brilliant red powder derived from carotenoids – capsanthrine, capsorubin, beta-carotene and others. Paprika is produced from the pods of Capsicum annum, a mild bell pepper. Formulators usually prefer to use paprika oleoresin due to its better light stability. Product applications include blends for curry powder, cereals, sauces and baked goods.

      Cinnamon can also provide a range of colors, depending on the type chosen. Cassia-type cinnamons, native to China and Indonesia, have a range of essential oil contents (cinnamic aldehyde), and provide a selection of aromas, flavors and color intensities. Ceylon-type cinnamon is very low in essential oils, and so is weak in color, flavor and aroma.

    The onion family

      Onions, Allium cepa, are among the top three ingredients used in recipes worldwide. (The other two are salt and pepper.) In the United States, each person consumes approximately 16 lbs. of onions per year. Fresh onions contain only about 0.01% essential oil, made up of a range of sulfide compounds. The trademark “crying effect” experienced when cutting onions is caused by thiopropanal-S-oxide and propenyl sulfenic acid. When onion is dried, its flavor and odor become more garlic-like.

      One of the best-selling herbal remedies in the United States is a member of the onion family, Alliaciae, but it’s not onion. Garlic has been used as an herbal treatment for centuries. The Greeks, Romans and Egyptians believed that it increased strength and speed, and they also used it to treat wounds, infections, tumors and parasites. Garlic’s numerous purported cardiovascular, antimicrobial, antioxidative, antitumor, and cholesterol-lowering properties – which the ancients knew through practical use – are now being reinforced by modern studies. Add to that its flavor and aroma in Italian, Indian and other ethnic dishes, not to mention its effect on vampires, and garlic’s popularity is easily understood. In fact, production of garlic has increased from 140 million lbs. in 1975 to greater than 500 million lbs. today.

      The active compounds in garlic are found throughout the onion family, which also includes chives. When garlic cells are damaged, alliin, an odorless amino acid, is converted by allinase to allicin, which is responsible for the characteristic odor and flavor of garlic. Allicin itself is relatively unstable, and is converted over time to ajoenes, dithiins and diallyl disulfide, all of which have been shown to possess antimicrobial, anticlotting and antioxidant activity. Garlic also contains vitamins B and C, selenium and sulfur.

      According to German clinical trials using a standardized tablet marketed under the name of Kwai, garlic users who consume 600 to 900 mg per day can lower serum cholesterol an average of 12%. Meanwhile, researchers at The Pennsylvania State University, University Park, have reported that heating can destroy garlic’s anti-cancer activity. As little as one minute in the microwave or 40 minutes of oven roasting can destroy the allinase responsible for the breakdown of alliin. However, if the garlic is crushed and allowed to stand for 10 minutes, the garlic retains anti-cancer activity (as determined in rat studies). These researchers also identified three water-soluble, sulfur-containing constituents – S-allyl cysteine, S-ethyl cysteine and S-propyl cysteine – that decrease cholesterol production by 40% to 60% in rat liver cells.

      One last word on garlic – researchers at Clemson University in Charleston, SC have reported that feeding 3% dietary garlic powder to chickens reduces odor in poultry houses. (The offensive odor normally produced gives a new punch line to the old “why did the chicken cross the road?” joke. Answer – to get upwind of the other chickens.) According to researchers, the house now smells “like a pizzeria.” It is also possible that the garlic powder could lower the cholesterol content of the chickens’ eggs. In a follow-up study, hogs were a little more finicky about their food, but adapted well. Clemson is exploring the potential for commercializing this research. However, anything that would raise the cost of chicken feed would need considerable benefits to counter that cost.

    Aromatherapy for the Mind and Body

    Aromatherapy – using essential oils for flavoring, preservation, fragrance and healing -has been used by many cultures for centuries. The name may be new to this century, but perfumes, incense and extracts of aromatic plants are still used for therapeutic purposes. Certain essential oils have become associated with particular moods or notes.

    • Top notes (stimulating): caraway, basil, coriander, eucalyptus, lemon, lime, sage
    • Middle notes (neutral mood): anise seed, sweet fennel, thyme, black pepper, lavender, hyssop, rosemary, peppermint, pine
    • Base notes (relaxing, sedative): cinnamon, clove, ginger, nutmeg, sandalwood, cedarwood

    According to aromatherapy literature, vapors can be inhaled to trigger a neurochemical release in the brain through receptors in the nose and mouth, causing the mood desired and/or evoking memories of specific personal history. Essential oils are also often used as a part of aromatherapy massage, where the oils can be worked into the skin, muscles and joints.

    Aromatherapy remedies can be found for arthritis, bronchitis, colds, diarrhea, eczema, and so forth – you can’t quite go to “z,” but there are therapies for any number of ills. Does it work? The general advice is to treat any form of aromatherapy with skepticism. It may be allright to try, but aromatherapy is mostly unsubstantiated, and some “remedies” could be harmful. And remember – it is not recommended to ingest essential oils as treatment. (However, consuming a freshly-baked cinnamon bun as a relaxant is highly recommended.)

    The nightshade family

      The nightshade, or Solanaceae family, includes tomatoes, tobacco and, most notably in this case, the genus Capsicum. Within this group are bell peppers (sweet, mild), tabascos, paprika, and habaneros (very hot). Red cayenne peppers, the hot variety of the Capsicum group, have been used for medicinal purposes since the 1500s. Believed to have originated in South America, cayenne was, according to early medical writings, used to “help digestion, provoke urine, relieve toothache, preserve the tooth from rottenness, comfort a cold stomach, expel the stone from the kidney, and take away the dimness of sight.”

      All capsicums contain a crystalline alkaloid known as capsaicin (vanillyl amids of isodenoic acid), which is responsible for the pungency, or heat. The level of capsaicin determines the level of heat, which is generally measured either as pure capsaicin or by the Scoville organoleptic test. The Scoville scale was developed in 1902, and ranks heat from zero to 300,000 Scoville units. Bell peppers measure 0 on the scale; cayenne 30,000 to 50,000; chipotle 75,000; jalepeño 5,000; and habeneros 100,000 to 300,000.

      Capsaicin and dihydrocapsaicin make up 80% to 90% of the capsaicinoids in peppers, and are the most pungent of the capsaicinoids. Also contained are nordihydro-, homo-, and homodihydrocysaicin.

      In addition to capsaicin, red peppers also are a good source of minerals including thiamine, iron and magnesium, and vitamins A, B, C, E, thiamin, niacin, riboflavin and beta-carotene, which leads to some use as a colorant, along with paprika. Paprika is a capsicum obtained by drying and grinding red peppers. The brilliant red color stems from the high carotenoid content. Taste, pungency and color depend upon the type of red pepper sourced. Color is measured by spectrophotometry and is expressed as ASTA color units. Paprika oleoresin is extracted with hexane or ethylene dichloride, and is generally used in sausages, cheeses, soups and sauces.

      Capsaicin has a rich history in alternative medicine, and a number of uses have been cited. It has been noted for its antimicrobial and antioxidative properties, leading to speculation that it may help to prevent cancer. Capsaicin has also been shown to provide relief for the oral mucositis (sores of the mouth) caused by chemotherapy. It acts by desensitizing the mucous membrane. When blended with sugar in a candy, it provides pain relief, while the sugar eases the capsaicin burn.

      A small amount of pepper in soft, baby-type food can help stroke patients swallow their food, according to Schwab Rehabilitation Hospital in Chicago. Also, according to the Herb Research Foundation, Boulder, CO, chili peppers can increase circulation in the stomach and intestines, helping digestion and decreasing flatulence.

      How can capsaicin have such wide-ranging effects? It has been suggested that capsaicin acts as a counter-irritant, reducing pain and swelling, aiding circulation, stimulating perspiration, and warming or cooling the extremities. Peppers can also help break up the respiratory effects of a cold, acting as an expectorant. In Russia, one potion consisting of a couple of pods in a bottle of vodka serves to treat both internal and external maladies. This concoction seems to relieve symptoms of colds, rheumatism and stomachache, as well as serve as an ingredient in a liniment to treat skin ailments or aches and pains in the joints.

      Studies are underway to confirm whether or not capsaicin, by increasing metabolic rate and body temperature, can increase the metabolism of body fat and/or slow fat absorption from the small intestine. Capsaicin is available in an over-the-counter drug, Zostrix®, for easing the pain of psoriasis, shingles, osteoarthritis and rheumatoid arthritis. Studies have also indicated that capsaicin may be instrumental in blocking production of “substance P,” which conveys the message of pain to the brain.

      Incidentally, capsaicin can bring an assailant to his knees with one good spray to the face – pepper spray can cause respiratory distress, eye irritation and choking. For this purpose, the more capsaicin, the better. Also, if pesky squirrels are a problem in a bird feeder, about 20,000 Scoville units on the feed will discourage squirrels, but does not affect birds.

      Black pepper and white pepper are not related to the red peppers, but come from the “peppercorn” of a climbing vine, Piper nigrum. The black pepper (which includes the dark skin of the berry) is more aromatic than the white (minus the skin), but the white is more pungent in flavor. Piperine, an alkaloid, provides the pungency. The essential oil content is 80% monoterpenes, with most of the remainder sesquiterpenes. Peppers increase appetite by stimulating the taste buds, aiding digestion and increasing gastric secretion.

    The ginger family

      If you were to prepare for a visit to the ginger family by looking up “ginger spice” in an Internet search engine, there’d certainly be a number of hits – but perhaps not many pertaining to food. This should be a temporary situation, though – Ginger has left the Spice clan, and things should return to “normal” soon. However, outside the music world, ginger belongs to the Zingiberaceae family, which contains some important aromatic and color-producing spices such as turmeric, ginger, cardamom, grains of paradise and galangal.

       When the roots of Curcuma longa are dried and ground, the result is a yellowish-orange powder called turmeric. At one time, turmeric was called Indian saffron – Marco Polo thought that he had discovered an inexpensive saffron substitute. India produces two types of turmeric: Madras, used within India, and Alleppey, which is exported. Alleppey has higher color, more flavor, more volatile oil, and more curcumin, the carotenoid responsible for the color. The active components of turmeric are the curcuminoids. Curcumin has an antioxidant effect, and it has been suggested that it has anti-inflammatory action similar to aspirin. The Chinese use turmeric to improve digestion and reduce gas, and to stimulate bile production in the liver. Herbalists recommend it for irritable bowel syndrome, colitis, Crohn’s disease, diarrhea, and post-salmonella infection. It is also said to improve beneficial intestinal flora, while inhibiting certain harmful bacteria.

      Oleoresin from ginger roots can be found in ginger ale, gingerbread, gingersnap cookies, ginger tea, ginger wine, cordials and candies, as well as a number of great Chinese, Indian and Jamaican dishes. The volatile oil of ginger contains zingiberene, AR-curcumene and farnesene, while the pungent taste is due to gingeroles and zingerone. In addition to its aromatic contribution to a food, ginger tea is often used to improve circulation, aid digestion, and treat nausea from motion sickness, pregnancy or chemotherapy.

      The ginger family also houses cardamom, whose sweet, aromatic seeds contain about 8% essential oil and a number of the previously mentioned compounds. In the past, cardamom was used as an aromatic in pomanders, and as an aphrodisiac. It is an essential part of Arabic coffee, and is also used in meat and rice dishes.

      Galangal is a warm, sweet, spicy aromatic root-stock like ginger. It blends well with garlic, and is considered to be an emerging ethnic ingredient, essential to many Asian dishes. Aromatic, spicy, warm and slightly bitter grains of paradise seeds are native to West Africa. In the Middle Ages, they were highly valued, but are difficult to obtain now.

    The parsley family

      Parsley, celery, coriander, cilantro, caraway, fennel, dill, anise and cumin belong to the Umbelliferae, or parsley family. We all know parsley leaves act as a garnish for a number of dishes, but the roots can also be used for cooking, as is celery. The fruits have a strong diuretic effect, and are used in stews or soups. Myristicin and terpenes dominate the essential oil of the fruits.

      Prior to the Middle Ages, a wild form of celery referred to as selinon, or smallage, was used as a diuretic and a carminative, which is a treatment to reduce intestinal gas. Today, celery – in dehydrated, flaked and freeze-dried forms – is often used as a garnish in vegetable dishes. Celery seed, salt and oleoresin are used primarily for flavor.

      Caraway is probably Europe’s oldest cultivated spice. In the past, it was used as a laxative, colic treatment and breath freshener. It has a pleasant odor similar to that of dill, and a warm, slightly bitter flavor stemming from a high concentration of carvone in the essential oil. In the 17th century, caraway was coated with sugar and served with fruit and used as a digestive, known as comfits.

      Caraway and cumin are sometimes confused – their flavors have some similarities, and their seeds are similar in appearance. In Germany, cumin and caraway are combined in a liqueur called kümmel. Cumin is essential to chili powder, and is often added on top for a “real” chili flavor. Herbalists recommend cumin tea for stress, and other cultures use it as a carminative. Researchers in India are studying cumin’s anti-cancer potential – it appears to increase the activity of glutathione-S-transferase, which is active against cancer, and also blocks chromosome damage.

      The word dill is derived from the Norse word for “to lull,” since it was used to lull small babies to sleep. American colonists used it for the same purpose, and also chewed the seeds for diversion in church. Today, we use two components of dill – dill seed, and the tops of the plant, which are referred to as dill weed. The seeds contain 2% to 4% essential oil, most of which is carvone (also present in caraway). The pickle industry is the largest user of dill, primarily dill-weed oil. Herbalists recommend dill tea for colic, and as a carminative.

      Fennel seeds look somewhat like caraway seeds (and cumin or dill), and smell and taste like anise, which is also part of the parsley family. The essential oils of both fennel and anise seeds contain predominately anethole, which is responsible for the licorice flavor and aroma. Fennel also contains fenchone, which smells like camphor, and limonene, which smells like lemon. In the past, fennel was regarded as a diet aid. Pliny felt that fennel improved eyesight, and fennel tea and eyewash are still recommended for strained eyes. Fennel tea is also used for colic, and as a muscle relaxant, diuretic, stimulant and carminitive. As with other parsley family seeds, our early ancestors chewed fennel seeds for diversion, to curb hunger and to freshen the breath.

      Both coriander and cilantro come from the same plant, Coriandrum sativum. Coriander is the dried ripened fruit, characterized by a lemon-sage note. It is used in seed, essential oil or oleoresin form. The seed is used primarily in gin and liqueurs, and is the flavor added to American cigarettes that makes them distinctive. Cilantro, sometimes known as Chinese parsley, has a parsley/citrus flavor, and is used in a dried or freeze-dried form. Cilantro is most common to Mexican sauces, Tex-Mex dishes, Chinese products and many other popular ethnic dishes.

    The mint family

      Lamiaceae, the mint family, hosts sage, basil, oregano, thyme, and rosemary – all of which have qualities beyond flavoring. Thyme is used for visual effect in foods, but its components also have antibacterial and antioxidant properties. In France, it is tied into bundles with other spices and added as bouquet garni to soups, sauces and stews. Thyme leaves are strongly aromatic; their essential oil contains primarily the phenols thymol and carvacol, as well as small quantities of thymol methyl ether, cineol, alpha-pinene and borneol. In legend, thyme has been used to soothe the throat, cure coughs, promote sleep and rid nightmares, improve digestion, cure hangovers, improve sight, warm the heart, soothe the liver, decrease hot swelling, purge phlegm, and cure pains in the loins and hips.

      Thymol, which is now produced synthetically, has been used as a carminative, anti-spasmodic and counter-irritant. It can be found in cough drops, antiseptic mouthwash, liniments, anti-fungal creams and herbal teas.

      The leaves of rosemary yield a product that is strongly aromatic (camphor-like) and slightly bitter. Rosemary has gained a reputation as a good natural antioxidant. The essential oil contains 1,8-cineol, camphor, borneol, bornyl acetate and alpha-pinene as primary components.

      Oregano is by far the largest-selling herb/spice today, mostly because of its heavy use on pizza and in Italian dishes. Oregano is a wild plant, but is often domestically cultivated as marjoram.

      Second on the list of best-selling herbs is sage, which was once grown in Middle-Age Europe and China specifically for medicinal purposes, and often taken as sage tea. Now, it is primarily used in pork sausage, poultry seasonings and stuffings.

      Use of basil, like its other mint relatives, has boomed over the past 30 years, from 40,000 lbs. imported to greater than a million lbs. – most of this due to pizza and Italian foods. In the past, basil has had more symbolic purposes than medicinal, but basil does have important antimicrobial and antioxidant properties. The essential oil contains a complex and widely varied composition, depending upon the species and environmental growth conditions. Linalool, methyl chavicol and eugenol play a role in aroma, while a number of monoterpenes, sesquiterpenes and phenols lend the flavor characteristics.

    Other families

      Cloves and allspice are both members of the myrtle family, Myrtaceae, and both are high in eugenol content. Eugenol is an alcohol noted for its antimicrobial properties. Cloves contain as high as 15% essential oil, with eugenol dominating at 70% to 85%. Cloves are noted for their strong aroma and burning taste, and have been used to freshen breath, as a room deodorant, and as a preservative. In the United States, they show up in baked ham, sweet pickles, and a variety of seasoning powders. Cloves dominate the flavor of Worcestershire sauce. Allspice has a distinctive clove-like aroma, and is frequently used in seasoning powders.

      Nutmeg and mace come from the same plant, Myristica fragrans, a nutmeg tree grown in India. Nutmeg is the seed, and mace is the thin tissue between the seed and the pulp. Both give off a strong aroma, contain 10% to 12% essential oil, and have antimicrobial and antioxidant properties from a complex mixture of terpenes, terpene derivatives and phenols. Notable among these are pinenes, terpinene, limonene, myrcene, linalool, terpineol, safrol, and myristicine. Myristicine is insecticidal and a hallucinogen, and the other components have anti-bacterial and antioxidant properties.

      Fenugreek, a seed extract from Trigonella, a member of the bean family, contains very little essential oil, but is known for its vanilla-scented coumarin and high mucilage content. It is used as an emollient in veterinary drugs, a poultice, and in tea for dyspepsia, diarrhea, sore throats and fevers.

      Science is only starting to learn the hows and whys of the intricate role that spices and herbs play in foods. So next time you think you’re only giving a product a flavor boost by sprinkling in the spice blend, remember that the secret world of spices might be working behind the scenes, providing a host of additional benefits


    Copyright 1997 by O. Peter Snyder

    Hospitality Institute of Technology and Management; St. Paul, Minnesota

    Spices and herbs have been used for thousands of centuries by many cultures to enhance the flavor and aroma of foods. Early cultures also recognized the value of using spices and herbs in preserving foods and for their medicinal value. Scientific experiments since the late 19th century have documented the antimicrobial properties of some spices, herbs, and their components (17, 20).

     Antimicrobial Effectiveness of Spices and Herbs
    Table 1 describes the relative antimicrobial effectiveness of some spices and herbs.

    Table 1. Antimicrobial Effectiveness of Spices and Herbs*

    Spices and HerbsInhibitory Effect
    Cinnamon, cloves, mustardStrong
    Allspice, bay leaf, caraway, coriander, cumin, oregano, rosemary, sage, thymeMedium
    Black pepper, red pepper, gingerWeak

     * Adapted from Zaika (20).

    Studies in the past decade confirm that the growth of both gram-positive and gram-negative foodborne bacteria, yeast. and mold can be inhibited by garlic, onion, cinnamon, cloves, thyme, sage, and other spices. Effects of the presence of these spices / herbs can be seen in food products such as pickles, bread, rice, and meat products. The fat, protein, water, and salt contents of food influence microbial resistance. Thus, it is observed that higher levels of spices are necessary to inhibit growth in food than in culture media (17). Table 2 is a list of various spices and herbs and their inhibitory effect on various microorganisms.

    Table 2. Inhibitory Effects of Spices and Herbs*

    Spice / Herb Microorganisms Reference 
    GarlicSalmonella typhymurium, Escherichia coli, Staphylococcus aureus, Bacillus cereus, Bacillus subtilis, mycotoxigenic Aspergillus, Candida albicans(1, 5, 9, 15)
    OnionAspergillus flavis, Aspergillus parasiticus(16)
    CinnamonMycotoxigenic Aspergillus, Aspergillus parasiticus(1, 3, 4)
    ClovesMycotoxigenic Aspergillus(1, 7)
    MustardMycotoxigenic Aspergillus(1)
    AllspiceMycotoxigenic Aspergillus(1, 7)
    OreganoMycotoxigenic Aspergillus, Salmonella spp., Vibrio parahaemolyticus(1, 2, 10, 12)
    RosemaryBacillus cereus, Staphylococcus aureus, Vibrio parahaemolyticus(19)
    Bay leafClostridium botulinum (8)
    SageBacillus cereus, Staphylococcus aureus, Vibrio parahaemolyticus (18, 19)
    ThymeVibrio parahaemolyticus(2, 12)

    * Adapted from Shelef (17).

    Microbial Contamination of Spices
    Spices and herbs may be contaminated because of conditions in which they were grown and harvested. Spores of both Clostridium perfringens and Bacillus cereus have been found to be present in spices and herbs (11, 13). Contaminated spices have been reported to have been causes of foodborne illness and spoilage. Fewer microorganisms are present in spices with higher antimicrobial activity such as sage, cloves, and oregano. However, all spices and herbs should be cleaned and decontaminated with ethylene oxide, irradiation, or other acceptable methods (6).

    Antimicrobial Compounds in Spices and Herbs
    Essential oils extracted from spices and herbs are generally recognized as containing the active antimicrobial compounds. Table 3 is a list of the proximate essential oil content of some spices and herbs and their antimicrobial components.

    Table 3. Antimicrobial Components of Spices and Herbs*

    Spice / Herb Proximate Essential Oil Content (%) Antimicrobial Component(s) 
    Garlic0.3 – 0.5Allicin
    Mustard0.5 – 1.0Allyl isothiocyanate
    Cinnamon0.5 – 2.0Cinnamaldehyde, Eugenol
    Cloves16 – 18Eugenol
    Sage0.7 – 2.0Thymol, Eugenol
    Oregano0.8 – 0.9Thymol, Carvacrol

    * Adapted from Shelef (17).

    Allicin and allyl isothocyanate are sulfur-containing compounds. Allicin, isolated from garlic oil, inhibits the growth of both gram-negative and gram-positive bacteria. Sulfur-containing compounds are also present in onions, leeks, and chives.

    Eugenol, carvacrol, and thymol are phenol compounds and, as Table 3 indicates, are found in cinnamon, cloves, sage, and oregano. The essential oil fraction is particularly high in cloves, and eugenol comprises 95% of the fraction. The presence of these compounds in cinnamon and cloves, when added to bakery items, function as mold inhibitors in addition to adding flavor and aroma to baked products. Paster et al. (14) have shown that essential oils of oregano and thyme (which contain carvacrol and thymol) are effective as fumigants against fungi on stored grain. These investigators have proposed using them as an alternative to chemicals for preseving stored grains.

    Antioxidant Action
    Spice extractives, such as oleoresin of rosemary, can provide inhibition of oxidative rancidity and retard the development of “warmed-over” flavor in some products. Thus, some spices not only provide flavor and aroma to food and retard microbial growth, but are also beneficial in prevention of some off-flavor development. These attributes are useful in the development of snack foods and meat products (6).

    Although the antimicrobial activity of some spices and herbs is documented, the normal amounts added to foods for flavor is not sufficient to completely inhibit microbial growth. The antimicrobial activity varies widely, depending on the type of spice or herb, test medium, and microorganism. For these reasons, spice antimicrobials should not be considered as a primary preservative method (6). However, the addition of herbs and spices can be expected to aid in preserving foods held at refrigeration temperatures, at which the multiplication of microorganisms is slow.

    Zaika (20) has given an excellent summary of the antimicrobial effectiveness of spices and herbs. A partial listing of this summary is as follows.

    1. Microorganisms differ in their resistance to a given spice or herb.
    2. A given microorganism differs in its resistance to various spices and herbs.
    3. Bacteria are more resistant than fungi.
    4. The effect on spores may be different than that on vegetative cells.
    5. Gram-negative bacteria are more resistant than gram-positive bacteria.
    6. The effect of a spice or herb may be inhibitory or germicidal.
    7. Spices and herbs harbor microbial contaminants.
    8. Spices and herbs may serve as substrates for microbial growth and toxin production.
    9. Amounts of spices and herbs added to foods are generally too low to prevent spoilage by microorganisms.
    10. Active components of spices / herbs at low concentrations may interact synergistically with other factors (NaCl, acids, preservatives) to increase preservative effect.
    11. Nutrients present in spices / herbs may stimulate growth and/or biochemical activities of microorganisms.

    Thus, food product safety and shelf life depend in some part on the type, quantity, and character of spices and herbs added to the products.


    1. Azzouz, M. A. and Bullerman, L. R. 1982. Comparative antimycotic effects of selected herbs and spices, plant components and commercial antifungal agents. J. Food Protect. 45:1248-1301.
    2. Beuchat, L. R. Sensitivity of Vibrio Parahaemolyticus to spices and organic acidsJ. Food Sci. 41:899-902.
    3. Bullerman, L. B. 1974. Inhibition of aflatoxin production by cinnamon. J. Food Sci. 39:1163-1165.
    4. Bullerman, L. B., Lieu, F. Y., and Seier, S. A. 1977. Inhibition of growth and aflatoxin production by cinnamon and clove oils, cinnamic aldehyde and eugenol. J. Food Science. 42:1107-1109, 1116.
    5. Dankert, J., Tromp, Th. F. J., Devries, H. and Klasen, H. J. 1979. Antimicrobial activity of crude juices of Allium ascalonicum, Allium cepa and Allium sativum. Zb. Bkr. Hyg., I. Abt. Orig. A245:229-239.
    6. Giese, J. 1994. Spices and seasoning blends: A taste for all seasons. Food Technol. 48(4):87-98.
    7. Hitokoko, H., Morozumi, S., Wauke, T., Sakai, S., and Kurata, H. 1980. Inhibitory effects of spices on growth and toxin production of toxigenic fungi. Appl. Env. Microbiol. 39:818-822.
    8. Huhtanen, C. N. 1980. Inhibition of Clostridium botulinum by spice extracts and aliphatic alcohols. J. Food Protect . 43:195-196, 200.
    9. Johnson, M. G., and Vaught, R. H. 1969. Death of Salmonella typhimurium and Escherichia coli in the presence of freshly reconstituted dehydrated garlic and onion. Appl. Microbiol. 17:903-905.
    10. Julseth. R. M. and Deibel, R. H. 1974. Microbial profile of selected spices and herbs at import. J. Milk Food Technol. 37:414-419.
    11. Kneifel, W. and Berger, E. 1994. Microbial criteria of random samples of spices and herbs retailed on the Austrian market. J. Food Protect. 57:893-901
    12. LLewellyn, G.C., Burkitt, M. L., and Eadie, T. 1981. Potential mold growth, aflatoxin production and antimycotic activity of selected natural spices and herbs. J. Assoc. Off. Anal. Chem. 64(4):955-960/
    13. Pafumi, J. 1986. Assessment of microbiological quality of spices and herbs. J. Food Protect. 49:958-963
    14. Paster, N., Menasherov, M., Ravid, U., and Juven, B. 1995. Antifungal activity of oregano and thyme essential oils applied as fumigants against fungi attacking stored grain. J. Food Protect. 58:81-85.
    15. Powers, E. M., Layer, R., and Masuoka, Y. 1975. Microbiology of processed spices. J. Milk Food Technol. 38:683-687.
    16. Sharma, A., Tewari, G. M., Shrikhande, A. J., Padwal-Desai, S. R., and Bandyopadhyay, C. 1979. Inhibition aflatoxin producing fungi by onion extracts. J. Food Sci. 44:1545-1547.
    17. Shelef, L. A. 1983. Antimicrobial effects of spices. J. Food Safety. 6 29-44.
    18. Shelef, L. A., Jyothi, E. K., and Bulgarelli, M. 1984. Effect of sage on growth of enteropathogenic and spoilage bacteria in sage containing broths and foods. J. Food Sci. 737-740, 809.
    19. Shelef, L. A., Naglik, O. A., and Bogen, D. W. 1980. Sensitivity of some common food-borne bacteria to the spices sage, rosemary, and allspice. J. Food Sci. 45(4):1045-1044.
    20. Zaika, L. L. 1988. Spices and herbs: Their antimicrobial activity and its determination. J. Food Safety. 9:97-118.



    Transfer Factor – Current status and future prospects

    H. Sherwood Lawrence and William Borkowsky

    Infectious Disease and Immunology Division, Departments of Medicine and Pediatrics, New York University Medical Center, 550 First Avenue, New York, NY 10016, USA

    We have detected new clues to the composition and function of “Transfer Factor” using the direct Leucocyte Migration Inhibition (LMI) test as an in vitro assay of Dialysates of Leucocyte Extracts (DLE). This approach has revealed two opposing antigen-specific activities to be present in the same >3500 <12,000 DA dialysis fraction – one activity is possessed of Inducer/Helper function (Inducer Factor). The opposing activity is possessed of Suppressor function (Suppressor Factor).

    When non-immune leucocyte populations are cultured with Inducer Factor they acquire the capacity to respond to specific antigen and inhibition of migration occurs. This conversion to reactivity is antigen-specific and dose-dependent. When immune leucocyte populations are cultured with Suppressor Factor their response to specific antigen is blocked and Inhibition of Migration is prevented.


    AIDS and Transfer Factor: Myths, Certainties and Realities.
    Dimitri Viza

    Laboratoire d’Immunobiologie, Faculté de Médecine des Saints-Pères, Paris.

    At the end of the 20th century, the triumph of biology is as indisputable as that of physics was at the end of the 19th century, and so is the might of the inductive thought. Virtually, all diseases have been seemingly conquered and HIV, the cause of AIDS, has been fully described ten years after the onset of the epidemic. However, the triumph of biological science is far from being complete. The toll of several diseases, such as cancer, continues to rise and the pathogenesis of AIDS remains elusive.

    In the realm of inductive science, the dominant paradigm can seldom be challenged in a frontal attack, especially when it is apparently successful, and only what Kuhn calls “scientific revolutions” can overthrow it. Thus, it is hardly surprising that the concept of transfer factor is considered with contempt, and the existence of the moiety improbable: over forty years after the introduction of the concept, not only its molecular structure remains unknown, but also its putative mode of action contravenes dogmas of both immunology and molecular biology. And when facts challenge established dogmas, be in religion, philosophy or science, they must be suppressed. Thus, results of heterodox research become henceforth nisi, i.e. valid unless cause is shown for rescinding them, because they challenge the prevalent paradigm.

    However, the triumph of biological science is far from being complete. The toll of several diseases continues to rise and the pathogenesis of AIDS, twelve years after the identification of the virus, remains by and large mysterious, while TF has been used successfully for treating viral infections including AIDS, as reported elsewhere. But when observations pertain to lethal disorders, their suppression in the name of dogmas may become criminal. Because of the failure of medical science to manage the AIDS pandemic, transfer factor, which has been successfully used for treating or preventing viral infections, may today overcome a priori prejudice and rejection more swiftly. In science, as in life, certainties always end up by dying, and Copernicus’ vision by replacing that of Ptolemy.


    Preliminary observations using HIV-specific transfer factor in AIDS.

    Giancarlo Pizza(1), Francesco Chiodo(2), Vincenzo Colangeli(2), Francesco Gritti(3), Enzo Raise(3), Hugh H. Fudenberg(4), Caterina De Vinci(1) & Dimitri Viza(5).

    (1)Immunodiagnosis and Immunotherapy Unit, 1st Division of Urology, Ospedale S. Orsola-Malpighi, Bologna, Italy; (2)Institute of Infectious Diseases, Ospedale S. Orsola-Malpighi, Bologna, Italy; (3)Dept. of Infectious Diseases and Immunopathology Unit, Ospedale Maggiore, Bologna, Italy; (4)Neuro ImmunoTherapeutics Found. Spartanburg, SC, USA; (5)Laboratoire d’Immunobiologie, URA 1294 CNRS, Faculté de Médecine des Saints-Pères, Paris, France.

    Twenty five HIV-1-infected patients, at various stages (CDC II, III and IV) were treated orally with HIV-1-specific transfer factor (TF) for periods varying from 60 to 1870 days. All patients were receiving antiviral treatments in association with TF. The number of lymphocytes, CD4 and CD8 subsets were followed and showed no statistically significant variations. In 11/25 patients the number of lymphocytes increased, whilst in 11/25 decreased; similarly an increase of the CD4 lymphocytes was observed in 11/25 patients and of the CD8 lymphocytes in 15/25. Clinical improvement or a stabilized clinical condition was noticed in 20/25 patients, whilst a deterioration was seen in 5/25. In 12/14 anergic patients, daily TF administration restored delayed type hypersensitivity to recall antigens within 60 days. These preliminary observations suggest that oral HIV-specific TF administration, in association with antiviral drugs, is well tolerated and seems beneficial to AIDS patients, thus warranting further investigation.



    Charles H. Kirkpatrick

    Innovative Therapeutics, Inc., Denver, CO, USA

    This report summarizes three components of our transfer factor research program. Several clinical studies have used oral administration of transfer factor containing materials. Sceptics have rejected these findings by assuming that the acidic and enzymatic environment of the gastrointestinal tract would destroy the factors. To further examine this issue, we have conducted dose-response studies of the delayed-type hypersensitivity reaction in mice that were given transfer factor either by gavage or subcutaneously. There were no difference in the responses that were related to the route of administration. We conclude that oral route of administration is efficacious and should be used when possible.

    We have also studied the effects of transfer factors on immune responses by recipients. The details of this research are presented in the paper by Dr. Alvarez-Thull. Briefly, the study showed that recipients of a specific transfer factor responded to the antigen for which the factor was specific by secreting gamma-IFN, but no other cytokines.

    The structures of transfer factor molecules are unknown. We have developed a process for isolating transfer factors in pure form and we have obtained preliminary data concerning amino acid sequences. Our goal is to obtain the complete primary structure of several transfer factor molecules.


    In vitro studies during long term oral administration of specific transfer factor.

    Giancarlo Pizza(1), Caterina De Vinci(1), Vittorio Fornarola(1), Aldopaolo Palareti(2), Olavio Baricordi(3) & Dimitri Viza(4).

    (1)Immunodiagnosis and Immunotherapy Unit 1st-Division of Urology, S. Orsola Malpighi Hospital, Bologna, Italy; (2)Department of Statistics, University of Bologna, Bologna, Italy;(3)Department of Genetics, University of Ferrara, Ferrara Italy; (4)URA 1294 CNRS, Laboratoire d’Immunobiologie, Faculté de Médecine des Saints-Pères, Paris, France.

    153 patients suffering from recurrent pathologies, i.e. viral infections (keratitis, keratouveitis, genital and labial herpes) uveitis, cystitis, and candidiasis were treated with in vitro produced transfer factor (TF) specific for HSV-1/2, CMV and Candida albicans. The cell-mediated immunity of seropositive patients to HSV-1/2 and/or CMV viruses was assessed using the leucocyte migration inhibition test (LMT) and lymphocyte stimulation test (LST) in presence of the corresponding antigens, and the frequency of positive tests before, during and after TF administration was studied. The data were stratified per type of test, antigen and the recipients’ pathology, and statistically evaluated. For the LMT, a total of 960 tests were carried out for each antigen dilution, 3 different antigen dilutions were used per test. 240/960 tests (25.4%) were found positive during non-treatment or treatment with unspecific TF, whereas 147/346 tests (42.5%) were found positive when the antigen corresponding to the specificity of the TF administered to the patient was used (P<0.001). When the data were stratified following pathology, a significant increased incidence of positive tests during specific treatment was also observed (0.0001<P<0.05). In the LST (1174 tests), a significant increase of thymidine uptake was observed in the absence of antigen (control cultures), during treatment with both specific and unspecific TF, but also in the presence of antigen and/or autologous serum during specific TF administration (P<0.0001).

    TF administration also significantly increased the soluble HLA class I antigens level, in 40 patients studied to this effect.


    The effect of DLE fractions on GM-progenitors of haematopoietic stem cells in vitro.

    Barnet K., Vacek A., Cech K. & Pekerek J.

    SEVAC a.s., Praha, Czech Republic.

    Dialysable leucocyte extracts (DLE) prepared from buffy coats of human blood, potentiates the effect of Colony-stimulating factor (CSF) on the growth of granulocyte-macrophage colony forming cell (GM-CFC) colonies in vitro. This relative increase of the number of colonies is apparent when diluted CSF (present in lung conditioning medium) as a control, and DLE, in a wide range of concentrations are added to the culture of mouse bone marrow cells. Fractionation of DLE on Amicon membranes revealed that the activity resides in molecules of 0-5kD. Molecules 5-10kD have no potentiating effect. DLE and its fractions (0-5kD, 0-1kD), except fractions 0-500 D and 5-10kD, when added undiluted i.e. at the initial concentration, exerted a suppressive effect: colonies are not formed despite the presence of CSF. In a pilot experiment, it was shown that DLE is able to stimulate colony-forming activity of earlier progenitors of erythroid cells (BFUe), under the influence of erythropoietin.


    The use of transfer factors in chronic fatigue syndrome: prospects and problems

    Paul H. Levine

    Viral Epidemiology Branch, National Cancer Institute, Bethesda, MD USA.

    Chronic fatigue syndrome (CFS) is a heterogeneous disorder characterized by severe prolonged unexplained fatigue and a variety of associated symptoms such as arthralgias, myalgias, cognitive dysfunction, and severe sleep disturbances. Many patients initially present with an acute onset of apparent infectious origin with either an upper respiratory or gastrointestinal illness, fever, chills, tender lymphadenopathy, and malaise suggestive of a flu-like illness. In some cases, specific viral infections can be identified at the outset, particularly herpes viruses such as Epstein-Barr virus (EBV), human herpes virus-6 (HHV-6), and cytomegalovirus (CMV). Transfer factors (TF) with specific activity against these herpes viruses has been documented. With some studies suggesting that persistent viral activity may play a role in perpetuation of CFS symptoms, there appears to be a rationale for the use of TF in patients with CFS and recent reports have suggested that transfer factor may play a beneficial role in this disorder. This report focuses on the heterogeneity of CFS, the necessity for randomized coded studies, the importance of patient selection and sub-classification in clinical trials, and the need to utilize specific end-points for determining efficacy of treatment.


    Lessons from a Pilot Study of Transfer Factor in Chronic Fatigue Syndrome

    Caterina De Vinci(1), Paul H. Levine(2), Giancarlo Pizza(1), Hugh H. Fudenberg(3), Perry Orens(4), Gary Pearson(2) & Dimitri Viza(5).

    (1)Immunodiagnosis and Immunotherapy Unit, 1st Division of Urology Sant’Orsola-Malpighi Hospital, Bologna, Italy; (2)Georgetown University, Washington DC, USA; (3)NeuroImmuno Therapeutics Foundation, Spartanburg SC, USA; (4)Great Neck, New York, NY, USA; (5)Laboratoire d’Immunobiologie, URA 1294 CNRS, Faculté de Médecine, Paris, France.

    Transfer Factor (TF) was used in a placebo controlled pilot study of 20 patients with chronic fatigue syndrome (CFS). Efficacy of the treatment was evaluated by clinical monitoring and testing for antibodies to Epstein-Barr virus (EBV) and human herpes virus-6 (HHV-6). Of the 20 patients in the placebo-controlled trial, improvement was observed in 12 patients, generally within 3-6 weeks of beginning treatment. Herpes virus serology seldom correlated with clinical response. This study provided experience with oral TF, useful in designing a larger placebo-controlled clinical trial.


    Use of anti HHV-6 transfer factor for the treatment of two patients with chronic Fatigue Syndrome (CFS). Two case reports

    Darham V. Ablashi(1&2), Paul H. Levine(3), Caterina De Vinci(4), John E. Whitman Jr.(1), Giancarlo Pizza(4) & Dimitri Viza(5).

    (1)Advanced Biotechnologies Inc, 9108 Guilford Road, Columbia, MD 21046 USA; (2)Department of Microbiology & Immunology, Georgetown University School of Medicine, Washington, DC 20007 USA; (3)Viral Epidemiology Branch, National Cancer Institute, Rockville, MD 20892 USA; (4)Immunotherapy Unit 1st Division of Urology, St. Orsola-Malpighi Hospital, Bologna, Italy;(5)URA 1294 CNRS Laboratoire d’lmmunobiologie, Faculté de Médecine des Saints-Pères, Paris, France.

    Specific Human Herpes virus-6 (HHV-6) transfer factor (TF) preparation, administered to two chronic fatigue syndrome patients, inhibited the HHV-6 infection. Prior to treatment, both patients exhibited an activated HHV-6 infection. TF treatment significantly improved the clinical manifestations of CFS in one patient, who resumed normal duties within weeks, whereas no clinical improvement was observed in the second patient. It is concluded that, HHV-6 specific TF may be of significant value in controlling HHV-6 infection and related illnesses.


    The influence of age on transfer factor treatment of cellular immunodeficiency, chronic fatigue syndrome and/or chronic viral infections.

    Ivo Hana(1), Jiri Vrubel(1), Jan Pekarek(2) & Karel Cech(2)

    (1)Dept. of Immunology, Institute for Clinical and Experimental Medicine; (2)Institute of Sera and Vaccines, Prague, Czechia.

    A group of 222 patients suffering from cellular immunodeficiency (CID), frequently combined with chronic fatigue syndrome (CFS) and/or chronic viral infections by Epstein-Barr virus (EBV) and/or cytomegalovirus (CMV), were immunologically investigated and treated with transfer factor (TF). The age range was 17-77 years. In order to elucidate the influence of aging on the course of the disease and on treatment, 3 subgroups were formed: 17-43 years, 44-53 years, and 54-77 years. Six injections of Immodin (commercial preparation of TF by SEVAC, Prague) were given in the course of 8 weeks. When active viral infection was present, IgG injections and vitamins were added. Immunological investigation was performed before the start of therapy, and subsequently according to need, but not later than after 3 months.

    The percentages of failures to improve clinical status of patients were in the individual subgroups, respectively: 10.6%, 11.5% and 28.9%. The influence of age in increasing the low numbers of T cells was evident: 10.6%, 21.2% and 59.6%. In individuals uneffected by therapy, persistent absolute lymphocyte numbers below 1,200 cells were found in 23.1%, 54.5% and 89.3% in the oldest group. Statistical analysis by Pearson’s Chi-square test, and the test for linear trend proved that the differences among the individual age groups were significant. Neither sex, not other factors seemed to influence the results.

    The results of this pilot study show that age substantially influences the failure rate of CID treatment using TF. In older people, it is easier to improve the clinical condition than CID: this may be related to the diminished number of lymphocytes, however, a placebo effect cannot be totally excluded.


    Rationale and clinical results of using leucocyte-derived immunosupportive therapies in HIV disease

    A.A. Gottlieb, R.C. Sizemore, M.S. Gottlieb & C.H. Kern

    Tulane University, 1430 Tulane Avenue, New Orleans, LA 70112; Imreg, Inc. 144 Elk Place Suite 1400, New Orleans, LA 70112

    Leucocyte dialysates contain a number of substances which exert important effects on human cell-mediated immunity. In this report, we describe several properties of a designated subfraction, IMREG(R)-1, which is obtained by a second dialysis against a membrane having a 3500 m.w. cutoff. These include the ability to augment and accelerate reactions of delayed hypersensitivity against antigens to which the text subject has been previously sensitized, and the ability to enhance the expression in vitro on CD4 lymphocytes of the p55 subunit of the receptor for Interleukin-2. We also report our observation that in a patient with advanced HIV disease whose lymphocytes had lost there ability to properly express the IL-2 receptor, treatment with IMREG(R)-1 over a period of months restored the expression of the IL-2 receptor on the patient’s CD4+ lymphocytes towards normal.


    Preliminary results in HIV-1-infected patients treated with transfer factor (TF) and Zidovudine (ZDV)

    Enzo Raise(1), Luca Guerra(1), Dimitri Viza(2), Giancarlo Pizza(3), Caterina De Vinci(3), Maria Luisa Schiattone(1), Leonarda Rocaccio(1), Maria Cicognani(1) & Francesco Gritti(1).

    (1)Dept. of Infectious Diseases and Immunopathology Unit, Clinical Pathology, Maggiore Hospital, Bologna, Italy; (2)Laboratoire d’Immunobiologie, Faculté de Médecine des Saints-Pères, Paris, France; (3)Immunotherapy Unit, 1st Division of Urology, Malpighi Hospital, Bologna, Italy.

    The efficiency of HIV-1 specific transfer factor (TF) administration, combined with Zidovudine (ZDV), in asymptomatic persistent generalised lymphadenopaty, or AIDS related complex (ARC) patients was evaluated.

    Twenty patients were randomly assigned to receive only ZDV (1st group) or ZDV together with HIV-1-specific TF (2nd group). HIV-1-specific TF was administered orally at 2 x 107 cell equivalent daily for 15 days, and thereafter once a week for up to 6 months. There were no significant differences between the two groups in clinical evolution, red blood cells, haemoglobin, lymphocytes, CD20 subset, transaminases, a-2-microglobulin, p24 antigen. White blood cells, CD8 lymphocytes as well as IL-2 levels increased in the second group, while the CD4 subset increased in the first group. The combination treatment with ZDV and TF appeared to be safe and well tolerated. Furthermore, levels of serum cytokines were investigated in 10 patients (8 asymptomatic and 2 ARC) treated with ZDV, and compared with 5 patients of the 2nd group (3 asymptomatic and 2 ARC) treated with ZDV plus HIV-1-specific TF. Peripheral lymphocytes, CD4, CD8 subsets, IL-2, TNFa, IL-6, p24 antigen, IL-2 soluble lymphocyte receptors (sR), CD4sR, CD8sR and a-2-microglobulin were evaluated at the baseline and at the 3rd month. The CD4 subset was not significantly different in the two groups, whilst IL-2 increased in the 2nd group, receiving ZDV plus TF, suggesting an activation of the Th1 secretion pattern.


    Inhibition of in vitro HIV infection by dialysable leucocyte extracts.

    C Fernandez-Ortega(1), M Dubed(2), O Ruibal(2), OL Vilarrubia(2), JC Menéndez de San Pedro(2), L Navea(2), M Ojeda1 & MJ Arana1.

    (1)Department of Cellular Biology, Center for Biological Research and Center for Genetic Engineering and Biotechnology, Havana, Cuba. (2)Laboratory for AIDS Research, Havana, Cuba.

    Dialysable Leucocyte Extract (DLE) is a low molecular weight dialysable material of disrupted peripheral human leucocytes with widespread effects on the immune system. We described the in vitro anti-HIV activity of DLE as well as its three chromatographic fractions (Fa, Fb and Fc). To determine the levels of inhibition on HIV replication by DLE we infected MT-4 cell cultures, using the Bru viral isolate at 0.05, 0.1, 0.5 and 1 m.o.i. Previously, MT-4 cells cultures were treated with DLE or fractions at non-toxic concentrations. Reverse transcriptase (RT) activity and p24 antigen were evaluated in culture supernatants at seven days postinfection. No effect was observed when MT-4 cells were incubated with DLE for 3 h. Whereas inhibition of HIV production was observed when MT-4 cells were pre-treated for a longer periods of time. DLE inhibited p24 production and RT activity more than 50% at 0.1 m.o.i. More than 80% of inhibition was observed for all doses of DLE tested at 0.05 m.o.i. Higher viral doses (m.o.i. 0.5 and 1) were used to assess the antiviral activity of DLE fractions. Fraction Fb inhibits viral production more than 80%. Otherwise, fractions Fa and Fc did not show inhibitory effect for any viral dose used. These results indicate that DLE is able to modulate cell susceptibility to Vvral infection in vitro.


    Dialysable leucocyte extract (DLE) reduces lipopolysaccharide-induced tumour necrosis factor secretion in human leucocytes.

    Miriam Ojeda Ojeda, Celia B. Fernandez Ortega & Manuel de J. Arana Rosanz.

    Department of Cell Biology, Center for Biological Research, P.O. Box 6996, Havana, Cuba.

    Dialysable leucocyte extract (DLE), obtained from lysed leucocytes, provide clinical effectiveness in a broad spectrum of diseases. Tumour necrosis factor (TNF) is raised in AIDS patients leading to increasing in human immunodeficiency virus (HIV) replication in vitro [1,2]. Whereas progression to AIDS in asymptomatic HIV infected individuals is retarded under treatment with DLE. In the present study we tested the DLE effect in vitro on both TNF biological activity (cytotoxicity) in L929 cells and its induction by lipopolysaccharide (LPS) in human monocytes as well as in whole blood from healthy donors. When monocytic cells were simultaneously exposed to LPS and DLE during a period of 5 1/2 hours, the induction of TNF was strongly diminished. The same inhibitory effect of DLE on TNF induction was observed when LPS was added to the culture medium prior to DLE. No significant effect of DLE on TNF-mediated cytotoxicity, even in the presence of the highest concentrations of DLE tested, was detected. DLE treatment of whole human blood regulates responses to LPS: simultaneous in vitro expose to endotoxin provokes a remarkable decrease (4- and 1.6-fold) of TNF release. In pre-incubation experiments, TNF production was largely reduced or completed abrogated. These results could, in part, explain the in vivo observed effect, when under treatment with this extract, the progression to AIDS of HIV-infected individuals was retarded. The results suggest that ‘natural’ substances like DLE may be important immunomodulators in inflammatory diseases.


    Effect of anti-herpes specific transfer factor.

    J. Byston, K. Cech, J. Pekarek & J. Jilkova

    Dept. of Allergology and Clinical Immunology, Faculty Hospital, Pavlova 6, Olomouc, Czech Republic

    Using a blood cell separator, lymphocytes were collected from otherwise healthy convalescents suffering from herpetic infections. A specific anti-herpes dialysate (AH-DLE) was prepared from the lymphocytes, using standard procedures. Patients with recurrent herpetic infections were treated with a single dose of the dialysate, at the initial signs of herpetic infection (group A), in two doses (group B) or in three doses (group C). A total number of 37 patients (29 women, 8 men, age range 15-73 years) were treated. No improvement was observed in 7 patients (18.9%), whilst 7 patients did not manifest any exacerbation of their herpetic infection in the course of the one-year follow-up. The remaining 62.2% of the patients showed a marked improvement: decrease of the frequency and/or duration or relapses. Before AH-DLE administration, the mean number of herpes relapses in this group of patients was 12 p.a.. After therapy, the number of relapses decreased to 3.5 p.a.. No statistically significant difference was observed between groups A and B. The least favourable results were registered in group C. However, this group included 6 female patients extremely resistant to the previously therapeutic attempts, including inosiplex, non-specific DLE or acyclovir. Thus, even in this group, the therapy was successful in 50% of the patients.


    Orally administered HSV-specific transfer factor (TF) prevents genital or labial herpes relapses

    Giancarlo Pizza(1), Dimitri Viza(2), Caterina De Vinci(1), Aldopaolo Palareti(3), Diego Cuzzocrea(1), Vittorio Fornarola(1) & Roberto Baricordi(4)

    (1)Immunodiagnosis and Immunotherapy Unit, 1st-Division of Urology, S.Orsola-Malpighi Hospital, Bologna Italy; (2)Laboratoire d’Immunobiologie, URA 1294 CNRS, Faculté de Médecine des Saints-Pères, Paris, France; (3)Department of Statistics, University of Bologna, Italy; (4)Department of Genetics, University of Ferrara, Italy.

    Forty-four patients, suffering from genital (22) and labial (22) herpes were orally treated with HSV-1/2-specific transfer factor(TF). TF was obtained by in vitro replication of a HSV-1/2-specific bovine dialysable lymphocyte extract. Treatment was administered bi-weekly the first 2 weeks, and then weekly for 6 months, most patients received 2-3 courses. The total observation period for all patients before treatment was 26660 days, with 544 relapses, and a relapse index of 61.2, whereas the cumulative observation period during and after treatment was 16945 days, with a total of 121 relapsing episodes and a cumulative RI of 21.4 (P<0.0001). Results were equally significant when the 2 groups of patients (labial and genital) were considered separately. These observations confirm previous results obtained with the bovine HSV-specific TF, and warrant further studies to establish HSV-specific TF as a choice of treatment for preventing herpes recurrences.


    Efficacy of transfer factor in treating patients with recurrent ocular herpes infections.

    Renato Meduri(1), Emilio Campos(1), Lucia Scorolli(1), Caterina De Vinci(2), Giancarlo Pizza(2) & Dimitri Viza(3).

    (1)Eye Physiopathology Clinical Service, University of Bologna, Italy; (2)Immunotherapy Unit, 1st Division of Urology, Ospedale O. Malpighi, Bologna, Italy; (3)Laboratoire d’Immunobiologie, URA 1294 CNRS, Faculté de Médecine des Saints-Pères, Paris, France.

    Recurrent ocular herpes is an insoluble problem for the clinician. As cellular immunity plays an important role in controlling herpes relapses, and other studies have shown the efficacy of HSV-specific transfer factor (TF) for the treatment of herpes patients, an open clinical trial was undertaken in 134 patients (71 keratitis, 29 kerato-uveitis, 34 uveitis) suffering from recurrent ocular herpetic infections. The mean duration of the treatment was 358 days, and the entire follow-up period 189121 before, and 64062 days after TF treatment. The cell-mediated immune response to the viral antigens, evaluated by the lymphocyte stimulation test (LST) and the leucocyte migration test (LMT) (P<0.001), was significantly increased by the TF treatment. The total number of relapses was decreased significantly during/after TF treatment, dropping from 832 before, to 89 after treatment, whereas the cumulative relapse index (RI) dropped, during the same period, from 13.2 to 4.17 (P<0.0001). No side effects were observed. It is concluded that patients with relapsing ocular herpes can benefit from treatment with HSV-specific TF.


    Transfer Factor as an adjuvant to non-small cell lung cancer (NSCLC) therapy

    Vladimiro Pilotti(1), Mario Mastrorilli(1), Giancarlo Pizza(2), Caterina De Vinci(2), Luciano Busutti(3), Aldopaolo Palareti(4), Giuseppe Gozzetti(1) & Antonino Cavallari(1).

    (1)Istituto di Clinica Chirurgica II, S. Orsola-Malpighi, Bologna, Italy; (2)Modulo di Immunoterapia Divisione di Urologia I, (3)Divisione di Radioterapia, Policlinico S. Orsola-Malpighi, Bologna, Italy; (4)Dipartimento di Statistica Universita degli Studi di Bologna, Italy.

    The rationale for using transfer factor (TF) in lung cancer patients is that the possibility of improving their cell-mediated immunity to tumour associated antigens (TAA) may improve their survival. From Jan 1984 to Jan 1995, 99 non- small cell lung cancer (NSCLC) resected patients were monthly treated with TF, extracted from the lymphocytes of blood bank donors. In the same period, 257 NSCLC resected patients were considered as non-treated controls. The survival rates of the TF treated group appear significantly improved both for patients in stages 3a and 3b, and patients with histological subtype “large cell carcinoma” (P<0.02). Survival of TF treated patients is also significantly higher (P<0.02) for patients with lymphnode involvement (N2 disease). The results of this study suggest that the administration of TF to NSCLC resected patients may improve survival.


    Transfer factor with anti-EBV activity as an adjuvant therapy for nasopharyngeal carcinoma: A pilot study

    Umapati Prasad(1), Mohd Amin bin Jalaludin(1), Pathmanathan Rajadurai(1), Giancarlo Pizza(2), Caterina De Vinci(2), Dimitri Viza(3) & Paul H. Levine(4)

    (1)University of Malaya, Kuala Lumpur, Malaysia; (2)Sant’Orsola-Malpighi Hospital, Bologna, Italy; (3)CNRS URA 1294, Laboratoire d’Immunobiologie, Faculté de Médecine des Saints-Pères, Paris, France; (4)National Institutes of Health, Bethesda, MD and George Washington University Cancer Center, Washington, DC, USA

    Overall survival of nasopharyngeal carcinoma (NPC) at UICC stage IV still remains unsatisfactory even with combination chemotherapy (CT) and radio-therapy (RT). In view of the association of reactivation of Epstein-Barr virus (EBV) with the development and recurrence of NPC, immunotherapy in the form of transfer factor (TF) with specific activity against EBV (TF-B1) was suggested as an adjuvant to a combination of CT and RT in order to improve the survival. In the present study, 6 UICC Stage IV patients received TF-B1 and another 6 patients matched for disease stage were given TF prepared from peripheral blood leucocytes (TF-PBL). Results were compared with another 18 patients matched by age, sex, and stage of disease who received standard therapy without TF during the same period (C group). After a median follow up of 47.5 months, the survival for the TF-B1 group was found to be significantly better (P=3D<0.05) than the PBL and C group. While the 8 patients with distant metastasis (DM) not treated with TF-B1 (6 in the control and 2 in the PBL group) died due to progressive disease (average survival being 14.3 months), both patients with DM in the TF-B1 group had complete remission: one died of tuberculosis after surviving for 3.5 years and another is still alive, disease free, after 4.2 years. Although the series involved a small number of cases, the apparent effect of adjuvant immunotherapy in the form of TF with anti-EBV activity is of considerable interest.


    A preliminary report on the use of transfer factor for treating stage D3 hormone-unresponsive metastatic prostate cancer

    Giancarlo Pizza(1), Caterina De Vinci(1), Diego Cuzzocrea(1), Domenico Menniti(1), Ernesto Aiello(1), Paolo Maver(1), Giuseppe Corrado(1), Piero Romagnoli(1), Ennio Dragoni(1), Giuseppe LoConte(1), Umberto Riolo(2), Aldopaolo Palareti(3), Paolo Zucchelli(4), Vittorio Fornarola(1) & Dimitri Viza(5).

    (1)Immunodiagnosis and Immunotherapy Unit 1st-Division of Urology, (2)Pharmacy, S.Orsola-Malpighi Hospital, Bologna; (3)Department of Statistics, University of Bologna, Bologna, Italy; (4)Blood Bank Service, Maggiore Hospital, Bologna. (5)Faculté de Médecine des Saints-Pères, Paris, France.

    As conventional treatments are unsuccessful, the survival rate of stage D3 prostate cancer patients is poor. Reports have suggested the existence of humoral and cell-mediated immunity (CMI) against prostate cancer tumour-associated antigens (TAA). These observations prompted us to treat stage D3 prostate cancer patients with an in vitro produced transfer factor (TF) able to transfer, in vitro and in vivo, CMI against bladder and prostate TAA. Forty four patients entered this study and received one intramuscular injection of 2-5 units of specific TF monthly. Follow-up, ranging from 1 to 9 years, showed that complete remission was achieved in 2 patients, partial remission in 6, and no progression of metastatic disease in 14. The median survival was 126 weeks, higher than the survival rates reported in the literature for patients of the same stage.


    Transfer factor in the age of molecular biology; A review.

    John M. Dwyer

    The Division of Clinical Immunobiology of the Prince Henry and Prince of Wales Hospitals of the University of New South Wales, Sydney, 2031, Australia

    Current data suggests that the transferring of immunologically specific information by transfer factor molecules requires interaction with a cell that has been genetically programmed to be antigen reactive but at the time of interaction is unprimed. Contact with transfer factor molecules would allow a naive recipient, on a first encounter with antigen, to make a secondary rather than a primary immunological response. Transfer factor molecules for each and every antigenic determinant are thus necessary. Transfer factors made from animals or humans are capable of transferring antigen specificity across a species barrier. Even primitive species have cells from which one can make transfer factors. The molecules are, therefore, well conserved and it is reasonable to suggest that they are important for normal immunological functioning. Proposed mechanisms of action must explain the fact that transfer factors obtained from the cells of high responder animals are capable of transferring delayed hypersensitivity to low responder animals while the reverse is not true. Transfer factor molecules are likely to interact with the variable regions of the alpha and/or beta chain of T cell receptors to change their avidity and affinity for antigen in a way that otherwise would only occur after an encounter with antigen.


    Dialysable lymphocyte extract (DLyE) in infantile onset autism: A pilot study.

    H.H. Fudenberg
    NeuroImmunoTherapeutics Research Foundation Spartanburg, S.C.

    40 infantile autistic patients were studied. They ranged from 6 years to 15 years of age at entry. 22 were cases of classical infantile autism; whereas 18 lacked one or more clinical defects associated with infantile autism (“pseudo-autism”). Of the 22 with classic autism, 21 responded to transfer factor (TF) treatment by gaining at least 2 points in symptoms severity score average (SSSA); and 10 became normal in that they were main-streamed in school and clinical characteristics were fully normalized. Of the 18 remaining, 4 responded to TF, some to other therapies. After cessation of TF therapy, 5 in the autistic group and 3 of the pseudo-autistic group regressed, but they did not drop as low as baseline levels.


    An attempt to inhibit the course of amyotrophic lateral sclerosis (ALS) by suppressor factor.

    Oldrich Nevsimal(1), Jan Pekarek(2) & Karel Cech(2).

    (1)Neurological Clinic of the Medical Faculty, Charles’s University, Praha, Czech Republic. (2)SEVAC Ltd. Praha, Czech Republic.

    Forty amyotrophic lateral sclerosis (ALS) patients were treated with suppressor factor. The therapy led to the normalization of the immunoregulatory index in approximately two thirds of the patients. The responder patients had a better clinical response, i.e. the degenerative process slowed down or it was even arrested. This favourable effect was accompanied with a significant increase in the patients’ life span. When the therapy had no effect on the CD8 cells, it was discontinued. Stopping the therapy led to disease progression and death; thus, in some patients, therapy was carried out despite its failure to increase the CD8 cell numbers. Substantial clinical improvement was noticed in these patients. The mean survival of patients with ALS was 2-3 years, whereas ALS patients treated with the suppressor factor survived on the average more than 5 years.


    Some properties and protective activity of specific DLE against Salmonella cholera suis infection.

    Atanas Arnaudov(1), Nicola Tziporkov(2).

    (1)Regional Veterinary Research Institute – Nezavisimost boul. 111, Plovdiv 46; (2)Higer Institute of Food and Flavour Industry, Biochemistry Dept.-Maritza boul. 26, Plovdiv 42, Bulgaria.

    From a rabbit lymphoid tissue, twice immunized with a Salmonella ch. suis vaccine, it was obtained a dialysable leucocyte extract (DLE) (m.w. 10000Da; protein content 1.14 mg/ml; content of ribose 2.7 mg/ml; A260/A280 ratio 2.17 and pH 6.8). By gel filtration on Sephadex G-25, six peaks were obtained and actively was found in peak IV. The activity of the extract was determined by a dermo-application test (DAT) on 10 cows. The protective effect was tested by challenge with Salmonella ch. suis and Salmonella dublin pathogen strains on white mice intraperitoneally treated with DLE. The DAT proved to be positive in 8 of the 10 cows. When applied on white mice, it induced a high specific protective effect against Salmonella ch. suis (70%), but not against Salmonella dublin infection.

    **** Dialyzable lymphoid extract (DLE) from mice resistant to STZ-induced diabetogenesis can interrupt the progress of diabetes in STZ-treated CD-1 mice.

    Wm. Borkowsky, Robert Pilson, and H.S. Lawrence.
    New York University Medical Center.

    Departments of Paediatrics and Medicine, Divisions of Infectious Diseases and Immunology, New York, NY, USA.

    DLE was prepared from the minority of euglycemic CD-1 mice, previously injected with STZ, and was administered to hyperglycemic CD-1 male mice 1, 2 and 3 weeks after completion of multidose STZ. Mice treated with DLE derived from 2 x 107 (1X) or 108 lymphocyte equivalents (lymph.equ.) were significantly less hyperglycemic than the saline treated controls (P<0.001). The effects of DLE remained evident for more than 10 weeks after the final DLE treatment. Mice treated with DLE prepared from diabetic mice (hg DLE) developed a somewhat more rapid onset of hyperglycemia than the STZ treated control animals, although this effect did not achieve statistical significance (P=0.1). This DLE was absorbed on a rat insulinoma cell line (RIN), which contains interspecies cross-reacting islet antigens, and compared to the unabsorbed DLE. Mice treated with hg DLE preabsorbed on RIN cells, showed a slower onset of hyperglycemia. DLE prepared from euglycemia mice and the RIN-absorbed fraction were equally capable of preventing hyperglycemia (P<0.05).

    In order to determine whether the DLE effects were genetically restricted, DLE was prepared from BALB/c mice, normally resistant to the diabetogenic effects of multidose STZ, both before and after STZ treatment. STZ primed CD-1 mice treated with 3 weekly doses of 2 x 10^7 lymph. equ. of untreated BALB/c derived DLE, STZ treated BALB/c derived DLE, and STZ treated CD-1 DLE were all less hyperglycemic than the control mice, who received saline (P<0.001). However, mice treated with CD-1 DLE were less hyperglycemic than the mice given BALB/c derived DLE (P<0.05). These effects were relatively long-lived.

    Mice that were given the >3,500 Dalton fraction of CD-1 DLE were significantly less hyperglycemic than either the control mice or those treated with the 3,500 Dalton fraction of CD-1 DLE (P<0.05). Effects remained evident for more than 3 months after the last dose of DLE. Pancreatic tissue from the mice treated with the >3,500 Dalton fraction of CD-1 derived DLE revealed slightly more islets of a slightly greater size with less surrounding inflammation than either control mice or mice treated with the <3,500 Dalton fraction of DLE.


    Influence of a DLE-extracted lymphocytic suppressor factor on CsA-induced immunosuppression

    V.E.M. Rosso di San Secondo, A. Aniasi, G. Piccolo, P.C. Montecucchi & G.Sirchia.

    Transplantation Immunology and Blood Transfusion Center, University-Hospital Policlinico, Via F.Sforza 35, 20122 Milano, Italy.

    From dialysable leucocyte extracts (DLE) we have purified a hydrophilic low-mol. wt. factor (about 1 kDa) which we have named lymphocytic suppressor factor (LSF) as it is able to suppress antigen- and mitogen-induced lymphocyte transformation and to prolong allograft survival in C57b/6N mice (H-2b) transplanted with fully mismatched skin from C3H/HeN mice (H-2k). At the molecular level LSF acts by inhibiting DNA replicational and transcriptional processes in activated lymphocytes, isolated rat hepatocyte nuclei, and cell-free systems. Amino acid analysis indicates that LSF is a peptide composed of Asp, Glu, Ser, Thr, Ala, Gly, Arg and probably Met, with the N-terminus blocked, possibly by pyroglutamic acid. When combined “in vitro” with cyclosporine A (CsA), LSF increased about 20 times the potency of CsA in inducing suppression of mitogen-stimulated lymphocytes. In C57b/6N mice with skin graft from C3H/HeN mice and undergoing immunosuppression with CsA (50 mg/kg/day), the splenocyte LSF content increased about 5 times. However, LSF values returned to normal in mice recovering normal responsiveness due to progressive withdrawal of CsA. These data show that LSF has an important role in the development and maintenance of CsA-induced immunosuppression. We suggest that, by influencing DNA replicational and transcriptional processes of lymphocytes, LSF may play a role also in the onset and progression of retro-viral diseases including AIDS.


    Transfer factor in chronic mucocutaneous candidiasis

    Massimo Masi(1), Caterina De Vinci(2), Olavio Roberto Baricordi(3).

    (1)Allergology and Clinical Immunology Center, Department of Pediatrics, University of Bologna; (2)Experimental Urology Unit, Division of Urology – S.Orsola-Malpighi Hospital, Bologna, Italy. (3)Department of Genetics, University of Ferrara, Italy

    Fifteen patients suffering from chronic mucocutaneous candidiasis were treated with an in vitro produced TF specific for Candida albicans antigens and/or with TF extracted from pooled buffy coats of blood donors. CMI of the patients was assessed using the LMT and the LST in presence of candidine. The aim of the study was the clinical evaluation of TF treatment and the incidence of positive tests before, during, and after therapy. Immunological data were matched using the Chi square test. 87 LMT were performed for each antigen dose and, at the dilution of 1/50, 58.9% (33/56) tests were positive during non-treatment or non-specific TF treatment. On the contrary 83.9% (26/31) were positive during specific TF treatment (P<0.05). In the LST, a significant decrease of thymidine uptake in the control cultures in presence of autologous or AB serum was observed when patients were matched according to non-treatment, and both non specific (P<0.05) and specific TF treatment (P<0.01). Only during specific TF treatment was a significant increase of reactivity against the Candida antigen at the highest concentration noticed when compared with the period of non specific treatment (P<0.01). Clinical observations were encouraging: all but one patient experienced significant improvement during treatment with specific TF. These data confirm that orally administered specific TF, extracted from induced lymphoblastoid cell-lines, increases the incidence of reactivity against Candida antigens in the LMT. LST reactivity appeared not significantly increased with respect to the periods of non treatment, but was significantly increased when it was compared to the non-specific TF treatment periods. At the same time, a clinical improvement was noticed.


    Profiles of cytokine production in recipients of transfer factors

    Linda Alvarez-Thull# and Charles H. Kirkpatrick

    Innovative Therapeutics, Inc. and #The Divisions of Allergy and Clinical Immunology National Jewish Center for Immunology and Respiratory Medicine and the University of Colorado Health Sciences Center Denver, Colorado.

    Transfer factors (TF) are proteins that transfer the ability to express cell-mediated immunity from immune donors to non-immune recipients. The mechanisms of these effects have not been defined. The experiments described in this report were undertaken to test the hypothesis that a mechanism through which the beneficial effects of TF are expressed in clinical situation is through “education” of the immune system to produce certain cytokines in response to antigenic stimulation.

    BALB/c mice were sensitized to Herpes simplex virus (HSV) either by sublethal systemic or cutaneous infections by administration of a HSV-specific TF. One week later their spleen cells were collected and single cell suspensions were stimulated in vitro with irradiated HSV or concanavalin A. Culture supernatants were collected and assayed for content of IL-2, IL-4, IL-10 and IFN-g.

    Spleen cells from infected mice responded to concanavalin A and to HSV by secreting large amounts of IL-2 and IFN-g, modest amounts of IL-10, and no IL-4. Transfer factor recipients produced similar cytokine profiles in response to concavalin A. These mice, however, responded to HSV by secreting IFN-g, but no IL-2. Thus, TF treatment selectively affects cytokine production in response to antigenic stimulation.


    Use of transfer factor for the treatment of recurrent non-bacterial female cystitis (NBRC): A preliminary report.

    Caterina De Vinci(1), Giancarlo Pizza(1), Diego Cuzzocrea(1), Domenico Menniti(1), Ernesto Aiello(1), Paolo Maver(1), Giuseppe Corrado(1), Piero Romagnoli(1), Ennio Dragoni(1), Giuseppe LoConte(1), Umberto Riolo(2), Massimo Masi(3), Giuseppe Severini(4), Vittorio Fornarola1 & Dimitri Viza(5).

    (1)Immunodiagnosis and Immunotherapy Unit, 1st-Division of Urology, Bologna; (2)Pharmacy, S.Orsola-Malpighi Hospital, Bologna; (3)Department of Pediatrics, S.Orsola-Malpighi Hospital, and Faculty of Medicine, University of Bologna, Bologna, Italy; (4)Division of Urology, S.Maria delle Croci Hospital, Ravenna, Italy; (5)Laboratoire d’Immunobiologie, URA 1294 CNRS, Faculté de Médecine des Saints-Pères, Paris, France

    Results of conventional treatment of female non-bacterial recurrent cystitis (NBRC) are discouraging. Most patients show an unexpected high incidence of vaginal candidiasis, while their cell mediated immunity to Herpes simplex viruses (HSV) and Candida antigens seems impaired, and it is known that the persistence of mucocutaneous chronic candidiasis is, mainly, due to a selective defect of CMI to Candida antigens.

    Twenty nine women suffering of NBRC, and in whom previous treatment with antibiotics and non-steroid anti-inflammatory drugs was unsuccessful, underwent oral transfer factor (TF) therapy. TF specific to Candida and/or to HSV was administered bi-weekly for the first 2 weeks, and then once a week for the following 6 months. No side effects were observed before treatment. The total observation period of our cohort was 24379 days, with 353 episodes of cystitis recorded and a cumulative relapse index (RI) of 43. The observation period during and after treatment was 13920 days with 108 relapses and a cumulative RI of 23 (P<0.0001). It, thus, seems that specific TF may be capable of controlling NBRC and alleviate the symptoms.


    Zou Zhao Fen, Hua Bao Lai, Liu Xiao Feng & Xue Jin Qi.

    Institute of Zoology, Chinese Academy of Sciences, Beijing, China Biochemistry Pharmaceutical Industry, Weixiuyvan of Beijing University, China

    The multipotential stem cells of bone marrow produce various kinds of cells in the blood stream and in the immune system, which play important roles in haemopoiesis and immune reactions. Proliferation of stem cells of bone marrow is the result of complex and precise inductions by cellular factors. In our experiments, the mitotic index (MI) of bone marrow in mice was measured in vivo by treating them with IFN (Interferon), DLE (Dialysable Leucocyte Extracts) and BMP (Bone Marrow Peptides) respectively.

    The results are as follows:
    1. IFN decreased the M.I of the control group to 62%; IFN has an inhibitory effect on stem cell proliferation.
    2. BMP has a stimulating effect on the proliferation of bone marrow cells, increasing MI by 140%.
    3. DLE has an immunoregulating function consisting in the maintenance of the M.I of bone marrow cells at the “normal” level, preventing, for instance, the proliferation of stem cells from being decreased by the side effects of IFN.

    Oral administration of DLE for longer time periods, increased the M.I of bone marrow cells of aged mice, from 44% to 104%, suggesting that DLE can enhance haemopoietic and immune functions of aged organisms and has, thus, anti-aging effects.


    Borisova E.V., Cheusova Z.V., Lolo A.A., Borisov V.A.

    Taras Shevchenko University, Biological Faculty, Kiev, Ukraine

    The influence of Salmonella Virchow extracts (both culture filtrate and lipopolisaccharide (LPS) extract) on delayed type hypersensitivity (DTH) to xenogeneic test-antigens in CBA mice has been examined. The LPS fraction is removed from the culture filtrate by gel filtration. It has been shown that intraperitoneal injection of live or killed bacteria, native or heated culture filtrates, and the LPS fraction suppress DTH. The immune-suppressive activity of the fractions disappears as soon as they are treated by phenol or trichloracetic acid, as well as by specific antibody adsorbtion. It was observed that transplantation of thymocytes from donor mice, which were previously treated by the culture filtrate or LPS, inhibits DTH to test-antigens in recipient mice. The transplant of bone marrow cells does not influence DTH in the recipients. The application on T-helper lymphocytes of levamisole treatment does not prevent Salmonella LPS immune-suppression. Furthermore, it has been shown that Salmonella-LPS inhibits activity of DTH-effector cells, whilst LPS induces T-cells to reduce activity of the T-effector cells which were not sensitized to LPS. The transfer factor of T-cells that have been processed by LPS lacks activity. It is hypothesized that failure of transfer factor treatment in Salmonella infections might be related to the LPS action.



    Ferrer V., Hernandez L., Miranda E., Gutierrez M. Mexico City, Mexico

    Post-herpetic neuritis (PHN) can be a dreadful complication of herpes, particularly in older patients, in whom it may last for months or years with severe pain, requiring strong pain relief medication with rather disappointing results. Furthermore, patients may present various degrees of disability due to the lack of strength of the affected region. We have tried Nonspecific Transfer Factor (NTF), extracted from leucocytes of normal blood donors, for the treatment of PHN in 17 patients with an evolution time of 8 days to 12 years. The patients with longer evolution times had received all types of pain relievers, e.g. carbamazepine and nerve blocks, with poor results. For instance, patient no.13 could hardly walk with the aid of a stroller. After receiving 3 to 12 Units of TF, all patients experienced a clear improvement of the pain, with total disappearance of the symptoms in 15 patients and residual light occasional pain in patients no.5 and no.11. We, thus, conclude that: 1) TF seems useful in the treatment of PHN and 2) the success of TF in the treatment of PHN suggests an active and continuous damage of the nerve by the herpes virus.


    HUMAN SPECIFIC TRANSFER FACTOR TO STAPHYLOCOCCUS ANTIGENS. Vershigora A.E., Lyubchenko T.A., Goleva E.G., Kholodna L.S., Pozur V.K., Stepanchuk V.A., Latysh G.I. Immunobiotechnological Center, Kiev University of T.Shevcenko, Ukraine. Forty-five male volunteers – donors of antistaphylococcal serum – were immunized with Staphylococcus anatoxin three times at weekly intervals. Fifteen additional volunteers were included in the control group. Dialyzable leukocyte extract (DLE) was obtained by conventional methods from the leukocytes of peripheral blood. Using both the agarose and capillary tube tests, it was shown that the DLE with Transfer Factor activity caused antigen-specific inhibition of macrophage and leucocyte migration. Furthermore, it increased rosette formation and lymphocyte transformation (blast formation). It is worth noting that DLE obtained from two of the immunized donors lacked in vitro activity, and also failed to transfer in vivo. ****


    ¯ Dark chocolate beats fatigue, study

    By Catherine Boal

    20/12/2006- Further evidence of the health benefits of chocolate has come to light in a new study – giving manufacturers yet another route into the functional food niche.

    Eating a small amount of dark chocolate each day can help combat the symptoms of Chronic Fatigue Syndrome (CFS), according to UK researchers.

    Dark chocolate has been frequently touted as a ‘healthy’ indulgence thanks to its high levels of polyphenols and flavanols which work to protect the body from cell damage. Sales of the product have risen as a result of its new health-conscious image and market analysts Leatherhead International say they now make up 19 per cent of global chocolate sales.

    In the study, the results of which are available on the Hull and East Yorkshire Hospitals NHS Trust website, researchers fed a group of adults 45g of specially formulated dark chocolate – containing 85 per cent cocoa and rich in polyphenols – every day for eight weeks.

    The participants reported feeling less fatigued after eating the chocolate and complained of greater tiredness when fed a placebo. None of those who took part reported any weight gain as a result of the study.

    Researchers believe chocolate enhances the action of neurotransmitters such as serotonin, responsible for regulating mood and sleep, which could explain why the product can alleviate CFS.

    Consultant endocrinologist at the NHS Trust, Professor Steve Atkin said: “No one has examined the effects of chocolate on CFS before and so this is a very interesting and exciting result for us.”

    “We now hope to look at some of the other potential benefits of chocolate which is high in these natural chemicals.”

    Extensive research into the healthy properties of dark chocolate has already been undertaken by confectionery giants Mars and Barry Callebaut in an effort to capitalise on scientifically-proven benefits which have recently come to light.

    And earlier this month, Barry Callebaut launched a website aiming to educate consumers on the science behind their cocoa processing method, Acticoa, which claims to reduce the loss of polyphenols common in ordinary manufacturing methods.



    ¯ Curcumin could cut plaque build-up linked to Alzheimer’s


    04/10/2006- Curcumin, found extensively in curries, could boost the body’s ability to clear the build up of plaques in the brain that are linked to Alzheimer’s disease, suggest results from a small laboratory study from the US.

    Alzheimer’s disease is the most common form of dementia and currently affects over 13 million people worldwide. The direct and indirect cost of Alzheimer care is over $100bn (€81bn) in the US alone. The direct cost of Alzheimer care in the UK was estimated at £15bn (€22bn).

    Although the mechanism of Alzheimer’s is not clear, significant data exists supporting the build-up of plaque from beta-amyloid deposits. The new research appears to indicate that curcumin, the natural pigment that gives the spice turmeric its yellow colour, could help the body’s immune system clear away these deposits and reduce the risk of developing the disease.

    “Curcumin improved ingestion of amyloid beta by immune cells in 50 percent of patients with Alzheimer’s disease. These initial findings demonstrate that curcumin may help boost the immune system of specific Alzheimer’s disease patients,” said Dr Milan Fiala from the David Geffen School of Medicine at UCLA.

    Curcumin has increasingly come under the scientific spotlight in recent years, with studies investigating its potential benefits for reducing cholesterol levels, improving cardiovascular health and cancer-fighting abilities.

    The research, published in the Journal of Alzheimer’s Disease (Vol. 10, pp. 1-7), adds to this by reporting on a small laboratory study using blood from six Alzheimer’s disease patients (aged 65 to 84) and three healthy controls. The focus was on macrophages, the ‘foot soldiers’ of the immune system that clean up harmful waste products in the body, including beta-amyloid deposits.

    The isolated macrophages were exposed to a curcumin-derived compound (provided by phytonutrient manufacturer Sabinsa Corporation) for 24 hours and then introduced beta-amyloid. It was found that macrophages from three out of six Alzheimer’s disease patients showed improved uptake or ingestion of the waste product compared to the patients’ macrophages not treated with curcumin.

    The age of the patient and the stage of the Alzheimer’s disease appeared to be key factors in the effectiveness of the curcumin compound, report the researchers, with younger patients and patients with early-stage Alzheimer’s apparently more receptive to the benefits.

    No effects were reported for the macrophages from the healthy controls when exposed the curcumin-derived compound.

    “We are hopeful that these positive results in a test tube may translate to clinical use, but more studies need to be done before curcumin can be recommended,” said Fiala.

    The mechanism behind these apparent effects is not clear and significant further study is needed to further examine the potential effects. Some caution is also warranted due to curcumin levels in some patients already being relatively high due to participation in another UCLA study.

    “Our next step will be to identify the factors that helped these immune cells respond,” said co-researcher Laura Zhang from UCLA.

    “Immunomodulation of the innate immune system by curcuminoids might be a safe approach to immune clearance of amyloidosis in Alzheimer’s Disease brain,” concluded the researchers.

    The new study extends previous findings examining the neuroprotective effects of curcumin. Experts recommend however that consumers wishing to make use of curcumin’s properties consume it in supplement form rather than eating more curries, which tend to be rather high in fat in their Western form.


    ¯ Curcumin linked to better performance for elderly brains




    10/27/2006- Curcumin, the natural pigment that gives the spice turmeric its yellow colour, could slow mental decline in elderly people by 49 per cent, suggests a study of non-demented Asian people.

    Cognitive performance declines naturally with age, but the results of the new study, published in the American Journal of Epidemiology (Vol. 164, pp. 898-906) suggests that eating curries “often or very often” had significantly better cognitive performance than those who “never or rarely” ate the dish.  The study adds to previous laboratory-based studies that showed that curcumin could boost the body’s ability to clear the build up of plaques in the brain that are linked to Alzheimer’s disease.

    Although the mechanism of Alzheimer’s is not clear, significant data exists supporting the build-up of plaque from beta-amyloid deposits. Recent research (Journal of Alzheimer’s Disease, Vol. 10, pp. 1-7) from the US appeared to indicate that curcumin could help the body’s immune system clear away these deposits and reduce the risk of developing the disease.  The Singapore National Mental Health Survey of the Elderly, led by Tze-Pin Ng from the National University of Singapore, recruited 1,010 elderly Asian subjects (average age 68.9) and compared scores for the Mini-Mental State Examination (MMSE).  The researchers report that for three different categories of curry consumption – “often or very often”, “occasionally” and “never or rarely” – and compared this with MMSE performance.  Ng and co-workers report that 43 per cent of the cohort consumed curry at least once a month to daily, while16 per cent never or rarely consumed the dish.

    When the researchers looked at the consumption of curry with measures of cognitive impairment (scores below 23 on the MMSE), it was reported that those who consumed curry “often or very often” were associated with a 49 per cent reduced risk of cognitive impairment, compared to those who never or rarely consumed. Eating curry “occasionally” was associated with a 38 per cent reduced risk.  “These findings present the first epidemiological evidence supporting a link between curry consumption and cognitive performance that was suggested by a large number of earlier experimental evidence,” wrote the researchers. The study has several limitations, including not taking into account vegetable and fat intake, which form part of curries, and the accuracy of the self-reporting of curry consumption.  Given these limitations, the researchers noted that the results should be “interpreted with caution,” and stated that dietary intakes may have changed as a result of the onset of dementia in some of the subjects. Despite such comments, the researchers point at turmeric as the potential source of the observed benefits.  “Interestingly, it has also been purported that the prevalence of Alzheimer’s disease in India among elderly between 70 and 79 years of age is four-fold less than that of the United States,” said Ng.  “The results reported here are therefore significant, as they point to a significant beneficial effect on cognitive functioning with even low-to-moderate levels of curry consumption.”  Curcumin has increasingly come under the scientific spotlight in recent years, with studies investigating its potential benefits for reducing cholesterol levels, improving cardiovascular health and cancer-fighting abilities. Some experts recommend however that consumers wishing to make use of curcumin’s properties consume it in supplement form rather than eating more curries, which tend to be rather high in fat in their Western form.



    Page 1 Capsaicin plus green tea combo aids weight loss

    Page 6 Green tea extracts may stop Parkinson’s

    Page 8 Bioflavonoids

    Page 14 Antioxidant Querciten and Green Tea on muscle performance

    Page 16 Remedy 1 and Recipes

    Page 18 Iodine and Heart Health

    Page 25 BLACK SEED

    Page 31 MRSA Remedies


    Capsaicin plus green tea combo aids weight loss

    A combination of capsaicin and green tea could promote the feeling of fullness and sustain satiety, indicating it could be successful for weight management, says a new study. Researchers from Denmark and the Netherlands report sweet pepper may also reduce energy intake during positive energy balance, according to findings of their 27-person study published in Clinical Nutrition. “We conclude that thermogenic food ingredients have energy intake reducing effects when used in combinations, and in positive energy balance,” wrote the researchers, led by Professor Margriet Westerterp-Plantenga from Maastricht University. “These results suggest that bioactive ingredients (capsaicin, green tea, CH-19) may be helpful in reducing energy intake to prevent body weight gain and may support body weight loss by relatively sustaining satiety and suppressing hunger,” they added. The research taps into the burgeoning weight loss and management market, estimated to already be worth $7bn (€5.2bn) globally. It also has implications for diabetes. With 50 per cent of Europeans and 62 per cent of Americans classed as overweight, the food industry is waking up to the potential of products for weight loss and management. The slimming ingredients market can be divided into five groups based on the mechanisms of action – boosting fat burning/ thermogenesis, inhibiting protein breakdown, suppressing appetite/ boosting satiety (feeling of fullness), blocking fat absorption, and regulating mood (linked to food consumption).

    Study details

    Westerterp-Plantenga and her co-workers recruited 27 people with an average age of 27 and an average BMI of 22.2 kg/m2, and randomised them to three weeks of negative (less calories consumed than used) and three weeks of positive energy balance (more calories consumed than used). During these periods ten separate test days were used to test the effects of capsaicin, green tea, CH-19 sweet pepper, capsaicin plus green tea, or placebo on appetite, energy intake, body weight and heart rate. Only the CH-19 and the capsaicin plus green tea combinations produced a reduction in energy intake during the positive energy balance period. Moreover, the combined supplement produced suppressed hunger and increased satiety, and this was greater during negative than positive energy balance, wrote the researchers. This indicated that energy balance did not affect energy intake but did affect appetite.

    Active components

    Commenting on the mechanism, the researchers note that both catechins and caffeine in green tea may be behind the effects, with epigallocatechin gallate (EGCG) previously noted to reduced food intake and body weight in rats. On the use of capsaicin the researchers note that long-term intervention is “hardly possible and results in bad compliance”, and that CH-19 sweet pepper, which is non-pungent, could be “an attractive alternative to capsaicin”. “Since CH-19 sweet pepper was an efficient suppressor of energy intake it would be of interest to investigate if a combination of CH-19 sweet pepper and green tea leads to a similar synergistic effect on energy intake,” wrote Westerterp-Plantenga and her co-workers. “Capsaicin only increases liking of the food when used at lower concentrations, and one can only comply with a relatively small dosage of capsaicin over the longer term. “Therefore we suggest that a lower dosage of capsaicin should be combined with other bioactive ingredients (e.g. CH-19 sweet pepper) in order to reach optimal effects,” they concluded.

    Source: Clinical Nutrition
    Published online ahead of print, doi: 10.1016/j.clnu.2009.01.010
    “Effects of capsaicin, green tea and CH-19 sweet pepper on appetite and energy intake in humans in negative and positive energy balance”Authors: H.C. Reinbach, A. Smeets, T. Martinussen, P. Møller, M.S. Westerterp-Plantenga Abstract available



    Hot Pepper (Capsicum spp.) protects brain from sodium nitroprusside- and quinolinic acid-induced oxidative stress in vitro.

    J Med Food. 2008 Jun;11(2):349-55

    Authors: Oboh G, Rocha JB

    One practical way through which free radical-mediated neurodegenerative diseases could be prevented is through the consumption of food rich in antioxidants. The ability of aqueous extracts of ripe and unripe Capsicum annum, Tepin (CAT) and Capsicum chinese, Habanero (CCH) to prevent lipid peroxidation induced by sodium nitroprusside and quinolinic acid in rat brain in vitro is assessed in this study. The aqueous extract of the peppers were prepared (1 g/20 mL). Incubating rat brain homogenates with pro-oxidant (7 microM sodium nitroprusside [222.5%] and 1 mM quinolinic acid [217.4%]) caused a significant increase (P < .05) in lipid peroxidation in rat brain homogenates. However, the aqueous extract of the peppers (4.2-16.8 mg/mL) caused a significant decrease (P < .05) in the lipid peroxidation in a dose-dependent manner. However, unripe CAT (92.5-55.2%) caused the highest inhibition of sodium nitroprusside-induced lipid peroxidation, while unripe CCH caused the least inhibition (161.0-102.1%). Furthermore, unripe CAT and CCH peppers had a significantly higher (P < .05) inhibitory effect on quinolinic acid-induced lipid peroxidation in rat brain than the ripe pepper (CAT and CCH). Therefore, the protection of the brain tissues by hot pepper depends on the total phenol content in sodium nitroprusside-induced lipid peroxidation, while ripening would reduce the protective properties of hot pepper against quinolinic acid-induced lipid peroxidation. However, unripe CAT has the highest protective properties against sodium nitroprusside- and quinolinic acid-induced lipid peroxidation in rat brain.



    Hot Pepper (Capsicum spp.) protects brain from sodium nitroprusside- and quinolinic acid-induced oxidative stress in vitro.

    J Med Food. 2008 Jun;11(2):349-55  Authors: Oboh G, Rocha JB

    One practical way through which free radical-mediated neurodegenerative diseases could be prevented is through the consumption of food rich in antioxidants. The ability of aqueous extracts of ripe and unripe Capsicum annum, Tepin (CAT) and Capsicum chinese, Habanero (CCH) to prevent lipid peroxidation induced by sodium nitroprusside and quinolinic acid in rat brain in vitro is assessed in this study. The aqueous extract of the peppers were prepared (1 g/20 mL). Incubating rat brain homogenates with pro-oxidant (7 microM sodium nitroprusside [222.5%] and 1 mM quinolinic acid [217.4%]) caused a significant increase (P < .05) in lipid peroxidation in rat brain homogenates. However, the aqueous extract of the peppers (4.2-16.8 mg/mL) caused a significant decrease (P < .05) in the lipid peroxidation in a dose-dependent manner. However, unripe CAT (92.5-55.2%) caused the highest inhibition of sodium nitroprusside-induced lipid peroxidation, while unripe CCH caused the least inhibition (161.0-102.1%). Furthermore, unripe CAT and CCH peppers had a significantly higher (P < .05) inhibitory effect on quinolinic acid-induced lipid peroxidation in rat brain than the ripe pepper (CAT and CCH). Therefore, the protection of the brain tissues by hot pepper depends on the total phenol content in sodium nitroprusside-induced lipid peroxidation, while ripening would reduce the protective properties of hot pepper against quinolinic acid-induced lipid peroxidation. However, unripe CAT has the highest protective properties against sodium nitroprusside- and quinolinic acid-induced lipid peroxidation in rat brain.

    RED PEPPER Capsaicin

    Possible health benefits
    All chili peppers contain phytochemicals known collectively as capsaicinoids.

    Capsaicin was shown, in laboratory settings, to cause cancer cell apoptosis in rats.[13]
    Recent research in mice shows that chili (capsaicin in particular) may offer some hope of weight loss for people suffering from obesity.[14][15]
    Canadian researchers used capsaicin from chillies to kill nerve cells in the pancreases of mice with Type 1 diabetes, thus allowing the insulin producing cells to start producing insulin again.[16][17]
    Research in humans found that “after adding chili to the diet, the LDL, or bad cholesterol, actually resisted oxidation for a longer period of time, (delaying) the development of a major risk for cardiovascular disease”.[18][19]
    Australian researchers at the University of Tasmania found that the amount of insulin required to lower blood sugar after a meal is reduced if the meal contains chili pepper.[20]
    Chilli peppers are being probed as a treatment for alleviating chronic pain.[21][22]
    Spices, including chilli, are theorized to control the microbial contamination levels of food in countries with minimal or no refrigeration.[23]
    Hot peppers can provide symptomatic relief from rhinitis and possibly bronchitis by thinning and clearing mucus from stuffed noses or congested lungs.[citation needed]
    Several studies found that capsaicin could have an anti-ulcer protective effect on stomachs infected with H. pylori by affecting the chemicals the stomach secretes in response to infection.[24][25][26]
    By combining an anesthetic with capsaicin, researchers can block pain in rat paws without causing temporary paralysis. This anesthetic may one day allow patients to be conscious during surgery and may also lead to the development of more effective chronic pain treatments

    Digestion  Cayenne can rebuild the tissue in the stomach and the peristaltic action in the intestines.  It aids elimination and assimilation, and helps the body to create hydrochloric acid, which is so necessary for good digestion and assimilation, especially of proteins.  All this becomes very significant when we realize that the digestive system plays the most important role in mental, emotional and physical health, as it is through the digestive  system that the brain, glands, muscles and every other part of the body are fed.


    Cayenne has been known to stop heart attacks within 30 seconds.  For example, when a 90-year-old man in Oregon had a severe heart attack, his daughter was able to get Cayenne extract into his mouth.  He was pronounced dead by the medics, but within a few minutes, he regained consciousness.  On the way to the hospital, he remained in a semi-conscious state, but the daughter kept giving him the Cayenne extract.  By the time they got  to the hospital, he had fully recovered and wanted to go home and mow the lawn.  The doctor asked what she had given him, as he said it was the closest thing to a miracle he had ever seen.  Heart Attacks: Cayenne


    ùùùGreen tea extracts may stop Parkinson’s
    By Stephen Daniells


    14/12/2007- The antioxidant effects of green tea polyphenols may protect neurons against the detrimental effects of reactive oxygen species (ROS) and nitric oxide (NO), thereby offering potential benefits for Parkinson’s, says new research from China.


    The study, conducted in rats, looked at the effects of green tea polyphenols (GTP) on inhibiting the death of neurons induced by the neurotoxin 6-hydroxydopamine (6-OHDA). The results are published in the journal Biological Psychiatry. Parkinson’s disease is a degenerative condition affecting movement and balance in more than one million Americans each year, a figure expected to rise due to ageing populations.  According to background information in the article, the disease is caused by an unrelenting process of cell death affecting the neurons containing pigmented dopamine (DA). Researchers, led by Baolu Zhao from the Institute of Biophysics, Academia Sinica, Beijing, randomly assigned male Sprague-Dawley rats to one of six groups: control-fed only; control-fed plus 6-OHDA; GTP (150 mg/kg/day) plus 6-OHDA; GTP (450 mg/kg/day) plus 6-OHDA; GTP (150 mg/kg/day) only; GTP (450 mg/kg/day) only. Green tea contains between 30 and 40 per cent of water-extractable polyphenols, while black tea (green tea that has been oxidized by fermentation) contains between 3 and 10 per cent. Oolong tea is semi-fermented tea and is somewhere between green and black tea.  The four primary polyphenols found in fresh tea leaves are epigallocatechin gallate (EGCG), epigallocatechin (EGC), epicatechin gallate (ECG), and epicatechin (EC).
    The mix used in this new study contained 50 per cent EGCG, 22 per cent ECG, 18 per cent EGC, and 10 per cent EC (Sichuan Full-green Biology Technology). Zhao and co-workers report that the green tea polyphenols protected against the toxic effects of 6-OHDA, with the higher dose producing a higher protective effect. Most notable, were the inhibition of increases in ROS and NO levels, and subsequent lipid peroxidation. “This study shows that, in vivo, GTP partially protected dopaminergic neurons (3.7 times more remaining neuron in GTP-treated than vehicle-treated animals) from 6-OHDA-induced cell death through ROS-NO pathway,” wrote the researchers.  Commenting independently on the study, John Krystal, editor of Biological Psychiatry and affiliated with both Yale University School of Medicine and the VA Connecticut Healthcare System said: “If green tea consumption can be shown to have meaningful neuroprotective actions in patients, this would be an extremely important advance.”He added a note of caution however, saying that many health-related benefits have been reported for a wide variety of naturally-occurring substances with many being contradicted by subsequent clinical trials. This is the case with St. John’s Wort and Ginko Biloba, he said. “Thus, it is extremely important to identify the putative neuroprotective mechanisms in animal models, as Guo and colleagues have begun to do for Parkinson’s disease,” said Krystal. Source: Biological Psychiatry (Elsevier) 15 December 2007, Volume 62, Issue 12, Pages 1353-1362  “Protective Effects of Green Tea Polyphenols in the 6-OHDA Rat Model of Parkinson’s Disease Through nhibition of ROS-NO Pathway”
    Authors: Shuhong Guo, J. Yan, T. Yang, X. Yang, E. Bezard and B. Zhao




    This is good news for women as a general rule you can live longer by eating flavonoids…..mind you I was a bit bias on the SOY, but I had to leave it in the report  because the isoflavones of soy are also classified as a flavonoid…but you notice in the report the flavones from soy are not mentioned  to much on how high they actually helped??? curious eh!!! the flavonoids daizeden and genisten ( from soy) have been actually attributed in blocking estrogen ( due to the fact that they are phytoestrogens) and convert to a foreign estrogen that can lead to a cancer of the reproductive area…..funny how this report sort of implies the benefits of flavonoids and lumps them altogether….it is a good report and the facts are about 98% accurate….so i think this is a good report to share with all of you, but i wanted to point out as well how something could be slipped into a report and you would asssume that a substance is safe just by association, notice no mentioning of how effective it was in reducing anything!!!!! I also added  some other info on Bioflavonoids.

    To your health eh!!!

    Greater intake of some flavonoids linked with reduced cardiovascular and all cause mortality among women over a 16 year period

    A report published in the March, 2007 issue of the American Journal of Clinical Nutrition described the finding of researchers at the University of Minnesota in Minneapolis and the University of Oslo that women whose intake of certain classes of flavonoids is high in comparison with other women have a reduced risk of cardiovascular and/or all cause mortality. Flavonoids are polyphenolic plant compounds that act as antioxidants, thereby helping to prevent the oxidation of LDL cholesterol. They may also benefit the heart by reducing inflammation, improving endothelial function, and inhibiting platelet aggregation.

    The current study evaluated data from 34,489 postmenopausal participants in the Iowa Women’s Health Study who were free of cardiovascular disease upon enrollment. Flavonoid intake from dietary questionnaires completed at the beginning of the study was classified, and the associated risk of death from cardiovascular disease, coronary heart disease, stroke, and all causes over a sixteen year period was calculated.

    Dietary flavonoids were classified as flavonoids, which includes flavonols, flavones, flavanones, flavan-3-ols and anthocyanidins; proanthocyanidins, and isoflavones (from soy). Among women who reported consuming anthocyanidins (found in blueberries, raspberries and red wine), the risk of coronary heart disease mortality, cardiovascular disease mortality, and total mortality was significantly lower than that of women who reported no anthocyanidin intake. For subjects in the top one fifth of flavanone (hesperitin, narigenin and eriodictyol) intake, there was a 22 percent reduction in the risk of coronary heart disease mortality compared with those who consumed the least amount, and for flavones (luteolin and apigenin) a 12 percent reduction in total mortality was determined. Individual foods associated with significant mortality reduction included bran, apples, pears, red wine, grapefruit, strawberries and chocolate. The study is the first of its kind, to the authors’ knowledge, to report on total flavonoids and their seven subclasses. “Results from this study suggest that the intake of certain subclasses of flavonoids may be associated with lower coronary heart disease and total cardiovascular disease mortality in postmenopausal women,” the authors write. “Furthermore, consumption of some foods that are high in flavonoid content or that are among the main sources of flavonoids in the diet of these study participants may have similar associations.”


    Here are some other bioflavonoids…….  Flavonoid polyphenolics (aka bioflavonoids)


    Bioflavonoids, a subset of polyphenol antioxidants, are present in many dark berries such as black currant, pomegranate, seabuckthorn, noni, blueberries, and blackberries, as well as in certain types of coffee and tea, especially green tea.

    Flavonols:Quercetin and related, such as rutin
    Myricetin – walnuts are a rich source
    Proanthocyanidins, or condensed tannins
    Flavanones:Hesperetin (metabolizes to hesperidin)
    Naringenin (metabolized from naringin)
    Flavan-3-ols (anthocyanidins):Catechin, Gallocatechin and their coresponding gallate esters
    Epicatechin, Epigallocatechin and their coresponding gallate esters
    Theaflavin its gallate esters
    Isoflavone phytoestrogens – found primarily in soy (which have  been found to be active in promoting cancerous growth on the reproductive system  after years of research), peanuts, and other members of the Fabaceae family. Besides having antioxidant characteristics, isoflavones also protect and maintain the skeletal system.Genistein ¯¯¯ DANGER
    Daidzein ¯¯¯ DANGER
    Stilbenoids:Resveratrol – found in the skins of dark-colored grapes, and concentrated in red wine.
    Pterostilbene – methoxylated analogue of resveratrol, abundant in Vaccinium berries
    Anthocyanins protect plants from UV damage:Cyanidin
    Phenolic acids and their esters

    See main article: Polyphenol antioxidant

    Ellagic acid – found in high concentration in raspberry and strawberry, and in ester form in red wine tannins.
    Gallic acid – found in gallnuts, sumac, witch hazel, tea leaves, oak bark, and many other plants.
    Salicylic acid – found in most vegetables, fruits, and herbs; but most abundantly in the bark of willow trees, from where it was extracted for use in the early manufacture of aspirin.
    Rosmarinic acid – found in high concentration in rosemary, oregano, lemon balm, sage, and marjoram.
    Cinnamic acid and its derivatives, such as ferulic acid – found in seeds of plants such as in brown rice, whole wheat and oats, as well as in coffee, apple, artichoke, peanut, orange and pineapple.
    Chlorogenic acid – found in high concentration in coffee (more concentrated in robusta than arabica beans), blueberries and tomatoes. Produced from esterification of caffeic acid.
    Chicoric acid – another caffeic acid derivative, is found only in the popular medicinal herb Echinacea purpurea.
    Gallotannins – hydrolyzable tannin polymer formed when gallic acid, a polyphenol monomer, esterifies and binds with the hydroxyl group of a polyol carbohydrate such as glucose.
    Ellagitannins – hydrolyzable tannin polymer formed when ellagic acid, a polyphenol monomer, esterifies and binds with the hydroxyl group of a polyol carbohydrate such as glucose.
    Other nonflavonoid phenolics

    Curcumin from tumeric
    Xanthones from noni
    Silymarin – mixture of flavonolignans extracted from milk thistle.
    Other plant pigments such as anthoxanthins and betacyanins.

    Other organic antioxidants

    Citric acid
    Lignan – antioxidant and phytoestrogen found in oats, flax seeds, pumpkin seeds, sesame seeds, rye, soybeans, broccoli, beans, and some berries.
    Antinutrients – strong antioxidants that readily bind to needed dietary minerals, rendering them unabsorbable in the gastrointestinal tract. Examples: oxalic acid and phytic acid.
    Bilirubin, a breakdown product of blood, has been identified as a possibly significant antioxidant.
    Uric acid In humans accouts for roughly half the antioxidant ability of plasme.
    R-a-Lipoic acid – fat and water soluble
    N-Acetylcysteine – water soluble


    Naringin normalizes Hematocrit (Blood Thickness) levels (i.e. it raises low Haematocrit levels and lowers elevated Haematocrit levels and has no effect on normal Haematocrit levels).  research

    Naringin promotes the elimination of old Red Blood Cells.  research


    Digestive System


    Naringin inhibits the ability of Alcohol (ethanol) to cause Gastric Ulcers.  research


    Immune System


    Naringin prevents or treats some types of Cancer:


    –        Naringin helps to prevent Breast Cancer.  research

    –        Naringin helps to prevent Lung Cancer.  research

    –        Naringin inhibits the metastasis of Melanoma:


    –        In mice studies, oral administration of Naringin inhibited the metastasis of Melanoma to the Lungs – Naringin-treated mice exhibited an 27% reduction in the number of Lung tumor nodules.




    Naringin lowers elevated serum Cholesterol levels.  research

    Naringin lowers elevated serum Triglycerides levels.  research


    Naringin Enhances the Function of these Substances




    Naringin extends the half-life of Caffeine.  research


    Pharmaceutical Drugs


    Naringin increases the bioavailability and potency of many Pharmaceutical Drugs and extends their half-life.


    Naringin Counteracts these Potentially Toxic Substances




    Naringin inhibits the activity of Aldose Reductase.

    Naringin inhibits the activity of HMG-CoA Reductase.  research


    Recreational Drugs


    Naringin inhibits the ability of Alcohol (ethanol) to cause Gastric Ulcers.  research


    Dietary Source of Naringin




    Naringin is a constituent of Grapefruit





    ùùùAntioxidant Querciten and Green Tea on muscle peformance


    Quercetin increases brain and muscle mitochondrial biogenesis and exercise tolerance

    J. Mark Davis,1 E. Angela Murphy,1 Martin D. Carmichael,1 and Ben Davis2

    1Division of Applied Physiology, Department of Exercise Science and 2Department of Communication Science and Disorders, Arnold School of Public Health, University of South Carolina, Columbia, South Carolina

    Submitted 13 November 2008 ; accepted in final form 6 February 2009

    Quercetin is one of a broad group of natural polyphenolic flavonoid substances that are being investigated for their widespread health benefits. These benefits have generally been ascribed to its combination of antioxidant and anti-inflammatory activity, but recent in vitro evidence suggests that improved mitochondrial biogenesis could play an important role. In addition, the in vivo effects of quercetin on mitochondrial biogenesis exercise tolerance are unknown. We examined the effects of 7 days of quercetin feedings in mice on markers of mitochondrial biogenesis in skeletal muscle and brain, and on endurance exercise tolerance. Mice were randomly assigned to one of the following three treatment groups: placebo, 12.5 mg/kg quercetin, or 25 mg/kg quercetin. Following 7 days of treatment, mice were killed, and soleus muscle and brain were analyzed for mRNA expression of peroxisome proliferator-activated receptor-  coactivator (PGC-1 ) and sirtuin 1 (SIRT1), and mitochondrial DNA (mtDNA) and cytochrome c. Additional mice underwent a treadmill performance run to fatigue or were placed in voluntary activity wheel cages, and their voluntary activity (distance, time, and peak speed) was recorded. Quercetin increased mRNA expression of PGC-1  and SIRT1 (P < 0.05), mtDNA (P < 0.05) and cytochrome c concentration (P < 0.05). These changes in markers of mitochondrial biogenesis were associated with an increase in both maximal endurance capacity (P < 0.05) and voluntary wheel-running activity (P < 0.05). These benefits of querectin on fitness without exercise training may have important implications for enhancement of athletic and military performance and may also extend to prevention and/or treatment of chronic diseases.

    flavonoid; mitochondria; endurance capacity

    Endurance capacity in maturing mdx mice is markedly enhanced by combined voluntary wheel running and green tea extract

    Jarrod A. Call,1 Kevin A. Voelker,1 Andrew V. Wolff,1,2 Ryan P. McMillan,1 Nick P. Evans,1 Matthew W. Hulver,1 Robert J. Talmadge,3 and Robert W. Grange1

    Departments of 1Human Nutrition, Foods and Exercise, and 2Mechanical Engineering, Virginia Polytechnic Institute and State University, Blacksburg, Virginia; and 3Biological Sciences Department, California State Polytechnic University, Pomona, California

    Submitted 11 January 2008 ; accepted in final form 24 June 2008

    Duchenne muscular dystrophy is characterized by the absence of dystrophin from muscle cells. Dystrophic muscle cells are susceptible to oxidative stress. We tested the hypothesis that 3 wk of endurance exercise starting at age 21 days in young male mdx mice would blunt oxidative stress and improve dystrophic skeletal muscle function, and these effects would be enhanced by the antioxidant green tea extract (GTE). In mice fed normal diet, average daily running distance increased 300% from week 1 to week 3, and total distance over 3 wk was improved by 128% in mice fed GTE. Running, independent of diet, increased serum antioxidant capacity, extensor digitorum longus tetanic stress, and total contractile protein content, heart citrate synthase, and heart and quadriceps β-hydroxyacyl-CoA dehydrogenase activities. GTE, independent of running, decreased serum creatine kinase and heart and gastrocnemius lipid peroxidation and increased gastrocnemius citrate synthase activity. These data suggest that both endurance exercise and GTE may be beneficial as therapeutic strategies to improve muscle function in mdx mice.


    Remedy 1

    Take gunpowder green tea and use 1 tablespoon add 1 tablespoon of powdered garlic or onion and add 1 tablspoon of the bioflavonids from dried whites from citrus ….pulverize them in a blender  until powdered….sift through a tea strainer or sifter    then re blend the left over , and re sift then when you have the powder add it to either honey or aloe vera blend til fused then consume as needed this should increase the effect of endurance and immune protection of lungs liver, immune system, will bind with metals as well as other toxic chemicals, and have a cancer preventative and combatative effect




    Take gunpowder green tea…21-3 tablespoons and ground it to a powder the add to a bowl ( sift to get out rough or unpowdered material)


    Take 1-2 teaspoons of the dried white of either grapefruit , orange, lemon , pomelo or lime or any other citrus you may like…powder and sift…Add to bowl….


    Then take 1 teaspoon of red pepper powder ( do the same if you buy fresh let dry then blend to a powder and sift ) put into bowl


    Add 1 cap of any alcohol ( brandy or cognac  or vodka or gin or even tequila) anything filtered is preferred


    Then add 2 tablespoons of honey ( unpasteurized )

    Put in the bowl


    Mix all of these you can either hand mix this or add to a blender and blend on low til everything is saturated and smooth….


    When down pour out into a glass bottle or container then use ½ tsp several times a day




    Other effects will be as well the Mass lose and potential satisfaction of food in the system, as well as an analgesic effect for pain on several different levels. All of these components as well have anti cancer fighting properties as well as arterial strengthening and heart regulating  effect, antibacterial qualities, and immune enhancing indication.

    The  effect can be felt almost immediately



    CCCAnother way of doing this is it mix 4 tablespoons of  powdered sifted green tea in a blender and add ½ cup of alcohol ( brandy ….vodka…cognac…etc) and blend for 10 minutes at a medium to high speed….. strain and add to a glass container


    Repeat this with the powdered dried bioflavonoid and the red pepper only add 1 tablespoon of the red pepper and only add a ¼ cup


    Once all these have been blended and strained then add equal parts of each into a dropper bottle ( 1 ounce or 15 ml) then use 3-5 drops ( It will be hot )



    You can apply the alcohol mix  in oil if need be to take or you can apply this to food or anything you may want to



    You will again feel the effect immediately so again do not take any prescription drugs with this


    You can how ever mix these with certain vitamins …such as

    Vitamin C


    Alpha Lipoic Acid

    Garlic ( when added to garlic it will have an increased effect with cholesterol lowering and  immune strengthening effect)



    Hawthorn Berry

    Rhodiola Rosea


    B1 or Benfotiamine

    Folic acid


    Beta Carotene


    Pine bark





    If you do mix this with these supplements Make sure you reduce the amount you take in a day or even rotate these every other day….it can impact the dose higher in the system, and as a result you can have a higher amount in the blood stream….so this can save you money as well as dosing……





    ùùùIodine and Heart Health

    International Medical Veritas Association ???


    Courtesy of Scientific American  According to Scientific American physicians for decades have grappled with ways to block further tissue damage in patients who suffer heart attacks. They have tried everything from drugs to cell therapy?all with little luck. But promising new research indicates that a biogel made from seaweed may have the healing powers that have thus far eluded them. Some of the principle healing agents in seaweed are magnesium, iodine, and selenium.  Though the main theme of this book is magnesium medicine for cardiac care we will deal in this chapter with iodine and in another with the important mineral selenium. Selenium is not only crucial when using iodine but it addresses most directly the Hun Hordes of Mercury that are attacking heart tissues in massive amounts leading to cardiac arrest. Mercury is a deadly cardiac poison whose best antidote is selenium – since they bind together making it easier for the body to remove the selenium-mercury compound.  Doctors and all health care practitioners need to be up on their minerals because we need them now more than ever. Minerals provide the foundations of our bodies as cement provides the support for most building foundations. We need to be acutely aware also of how the minerals work together and are dependent on each other for functioning at optimal levels. It is important that mineral interactions be taken into account when looking at iodine supplementation. A person with superior nutrient intake, especially of selenium, will be much more likely to respond well to higher intakes of iodine. Seaweeds (iodine) have exceptional value in the treatment of candida overgrowth. They contain selenium and (all the) other minerals necessary for rebuilding immunity; furthermore the rich iodine content is used by enzymes in the body to produce iodine-charged free radicals which deactivate yeasts. Experiments have shown that k. japonica, edible seaweed, was able to transform inorganic selenium to organic selenium through metabolism. Seaweed was crucial in the evolution of life in that it was and still is responsible for concentrating iodine from the ocean. The Japanese eat more seaweed then anyone in the world and they enjoy some of the best health statistics for it. Clinical cardiovascular features of hypothyroidism include: bradycardia, reduced cardiac output, increased pericardial and pleural effusions, increased diastolic blood pressure and peripheral vasoconstriction. According to Dr. Stephen A. Hoption Cann, Department of Health Care and Epidemiology, University of British Columbia, iodine deficiency can have deleterious effects on the cardiovascular system, and correspondingly, that a higher iodine intake may benefit cardiovascular function.[ii] Regional iodine intake has been shown to be associated with the prevalence of hypothyroidism and hyperthyroidism, where autoimmune hypothyroidism is the more common of the two in regions with moderate to high iodine intake. Both of these thyroid abnormalities have been shown to negatively affect cardiovascular function. Selenium, an important antioxidant in the thyroid and involved ?in the metabolism of iodine-containing thyroid hormones, may ?play an interactive role in the development of these thyroid irregularities, and in turn, cardiovascular disease.  Dr. Stephen. Hoption Cann  Dr. Michael Donaldson says, Iodine stabilizes the heart rhythm, lowers serum cholesterol, lowers blood pressure, and is known to make the blood thinner as well, judging by longer clotting times seen by clinicians. Iodine is not only good for the cardiovascular system, it is vital. Sufficient iodine is needed for a stable rhythmic heart beat. Iodine, directly or indirectly, can normalize serum cholesterol levels and normalize blood pressure. Iodine attaches to insulin receptors and improves glucose metabolism, which is good news for people with diabetes. Iodine and iodine-rich foods have long been used as a treatment for hypertension and cardiovascular disease; yet, modern randomized studies examining the effects of iodine on cardiovascular disease have not been carried out  Adequate iodine is necessary for proper thyroid function. The heart is a target organ for thyroid hormones. Marked changes occur in cardiac function in patients with hypo- or hyperthyroidism.  The country of Finland is an excellent case study of cardiovascular disease and iodine, as reviewed by Dr. Cann. Endemic goiter was common in people and in domestic animals, particularly in the eastern part of Finland away from the sea. Studies in the 1950s revealed that the major dietary difference between eastern and western Finland was iodine. The risk of death from coronary heart disease was 3.5 times higher for people with a goiter in Finland .[iv]  “Thyroid hormone is an important regulator of cardiac function and cardiovascular hemodynamics. Triiodothyronine, (T(3)), the physiologically active form of thyroid hormone, binds to nuclear receptor proteins and mediates the expression of several important cardiac genes, inducing transcription of the positively regulated genes including alpha-myosin heavy chain (MHC) and the sarcoplasmic reticulum calcium ATPase. [v] Negatively regulated genes include beta-MHC and phospholamban, which are down regulated in the presence of normal serum levels of thyroid hormone. T(3) mediated effects on the systemic vasculature include relaxation of vascular smooth muscle resulting in decreased arterial resistance and diastolic blood pressure. In hyperthyroidism, cardiac contractility and cardiac output are enhanced and systemic vascular resistance is decreased, while in hypothyroidism, the opposite is true. Patients with subclinical hypothyroidism manifest many of the same cardiovascular changes, but to a lesser degree than that which occurs in overt hypothyroidism. Cardiac disease states are sometimes associated with the low T(3) syndrome.?[vi] The phenotype of the failing heart resembles that of the hypothyroid heart, both in cardiac physiology and in gene expression. Changes in serum T(3) levels in patients with chronic congestive heart failure are caused by alterations in thyroid hormone metabolism suggesting that patients may benefit from T(3) replacement in this setting.”[vii] T(3) of course is iodine dependent so the relationship between iodine and heart disease gets clearer.  Iodine-containing thyroid hormones, thyroxine (T4) and triiodothyronine (T3), are important metabolic regulators of cardiovascular activity with the ability to exert action on ?cardiac myocytes, vascular smooth muscle, and endothelial cells.  Dr. Stephen. Hoption Cann Whole body sufficiency of iodine/iodide results in optimal cardiac functions, writes Dr. Guy Abraham.[viii] There is an epidemic of cardiac arrhythmias and atrial fibrillation in this country and Dr. Abraham is convinced that the medical iodine phobia has a great deal to do with this phenomenon. Adequate stores of iodine are necessary for a smooth heartbeat.[ix] The thyroid hormone deficiency on cardiovascular function can be characterized with decreased myocardial contractility and increased peripheral vascular resistance as well as with the changes in lipid metabolism.[x] Dr. B. West says, Iodine supplementation may be the missing link in a good percentage of heart arrhythmia cases, especially atrial fibrillation. The body needs adequate stores of iodine for the heart to beat smoothly. After close to a year now of using Iodine Fulfillment Therapy, I can attest to this fact.  Most of the stubborn cases of cardiac arrhythmias and atrial fibrillation that we were unable to completely correct with our cardiac protocols have now been resolved with adequate supplies of iodine added to the protocol.[xi] Amazingly, while medicine shuns iodine therapy, their most popular anti-fibrillation drug, Amiodarone, actually is iodine in a more toxic, sustained-release form. This drug can produce a smooth heartbeat when the body has accumulated about 1,500 mgs of iodine the exact amount of iodine retained by your body when iodine fulfillment is achieved by natural supplementation with Prolamine Iodine. Unfortunately, Amiodarone is an extremely toxic form of iodine used by the medical profession. The side effects are often too great (and even life threatening) for most people to endure long enough to achieve a normal heartbeat. In addition, once you stop this drug, your original problem returns. Iodine therapy, on the other hand, fulfills the body?s needs safely, then maintains the smooth heartbeat with a low-maintenance dose, continued Dr. West.  Dr. Donaldson reminds us of the selenium iodine connection saying,  Another factor in how much iodine can be safely used depends on other possible mineral deficiencies. Selenium is very important for thyroid function. Selenium is part of the antioxidant enzyme glutathione peroxidase. Glutathione peroxidase in the thyroid helps quench free-radicals produced by the enzyme thyroid peroxidase (which functions to organify iodide as it enters the thyroid). If high levels of iodide are present in the thyroid without sufficient amounts of glutathione peroxidase it causes free-radical damage to the thyroid, leading to autoimmune thyroid disease. Several of the enzymes that convert T4 into T3 also require selenium. Studies in Zaire have found that supplementing selenium and iodine deficient children with just selenium had adverse effects on thyroid function.[xii]  The selenium content in seaweed can bind with whatever mercury is present and render it harmless.  There are just some people who understand the basics of cellular medicine and act appropriately. Dr. John Young in Tampa Florida has been experimenting with a new process for reversing metabolic syndrome and Type 2 diabetes. Over the past seven years he claims to have a success rate of 80 percent with over 100 diabetes patients. Dr. Young uses a combination of alkaline protein and minerals with a form of iodine that he says reverses the process in diabetes patients in eight to 12 weeks.  It’s important to remember that diabetes and heart disease share similar etiologies. Whatever Dr. Young is doing for his diabetic patients physicians can be doing for their heart patients. Iodine is critical to the heart and arterial system so we know it needs to be part of a fundamental protocol either in a preventative or treatment sense. Dr. George Flechas has found that iodine can reduce the need for insulin in diabetic patients, using 50 to 100 mg of iodine per day. Of 12 patients, 6 were able to completely come off their medications with random glucose readings below 100 mg/dl and a HbA1c less than 5.8 (normal), and the other 6 were able to reduce the amount and/or number of medications needed to control their diabetes. There is a patient who had severe mitral valve prolapse. A 35-year old banker who could not walk more than 20 metres without?getting cyanosed. Five cardiologists and surgeons suggested open heart surgery immediately. He decided against the surgery and went to the DaVinci Clinic in Cyrus to my colleague Dr. George Gorgiou. A central part of the pathology was severe mercury toxicity of the heart tissues – he removed 14 amalgams poisoning himself in the process which caused severe mitral valve prolapse. With the correct treatment not only did this man survive but nearly a year later he is now wind surfing 12 miles at competition standard and came first two weeks ago in a race with two others. He is working a full life etc.  The patient actually has registered with the Guiness Book of Records as being the only man on this planet who has completely healed of severe mitral valve prolapse without open-heart surgery. Dr. Georgiou is a naturopathic doctor whose speciality is chelation of heavy metals. He has done research in Russia creating his own natural chelator called HMD. There are doctors out in the field who understand what is actually going on in cardiac patients and treat them in ways mainstream cardiologists don’t even dream of. Basic to this man’s treatment was magnesium, iodine and natural chelation with the HMD and other naturopathic support medicinals.


    My soon to be released book on Iodine is dedicated to the iodine doctors, brave souls who have risked bringing medicine back to some semblance of sanity. Iodine offers us such a return; it is bedrock medicine and is almost as useful as magnesium chloride. The above is the last chapter written for the book and represents a breakthrough in cardiac care. Having just finished the book it still amazes me the mysteries of iodine. I am known in certain circles as the magnesium man but with the publishing of this book I am definitely in the iodine camp. The experience of the past few days though are transforming me into an iodine man as well.  My whole family came down with something that has been going around the neighborhood, let’s call it the flu. As the first winds of it approached my body?s senses I ran for the iodine and took strong doses of it every hour or two and it beat the invading devils, headed them off right at the pass. I still got the symptoms of cough and running nose but I did not feel or get what most people call sick. I was right on the edge for a day but each time I took the iodine I could feel it giving me strength. The only side effect was that my mind intensified in clarity, my sleep time was reduced and I woke up fresh and ready to run to my work. I just this moment said to one of my son’s, who is suffering from the flu that he and I were both ignorant, meaning he did not think to take the iodine and until this week I never had for this purpose either. I have done so for my little children when they have gotten sick but there is nothing like first hand experience. I was using the Nascent Iodine[xiii], which I believe is the safest and most effective of the iodines available and for the children I would only use this. It is not as concentrated as Lugol’s, even the newer watered down Lugol?s, which is mostly what is available in the United States after some laws changed, is much stronger. I thus recommend Lugol’s for transdermal iodine therapy. Many of the iodine doctors use Iodoral or Iosol and with these one can take iodine dosages up to very high levels safely. The Nascent is something different, having powerful effects at much lower dosages. Feeling it in ones mouth hour after hour gives one a sense of amazement about iodine.  Considering the importance of this element for overall well-being, it is most amazing that no study so far has attempted to answer the very important question about what the optimal amount of daily iodine intake should be for the greatest levels of mental and physical well-being in the majority of a population with a minimum of negative effects. The more one experiences iodine the higher ones estimate goes in this regard.  An important note that the CDC would not like you to know is that Russian researchers and experts in mercury have correlated the flu with mercury toxicity more than with little bugs that crawl around inside of us. And behold, iodine chelates mercury as it does fluoride, bromide and even percolate, the halogen like rocket fuel polluting half of North America . In The Ultimate Heart Medicine book we see that mercury is a huge problem for heart muscles, which concentrate it to levels thousands of times higher than seen in other tissues.  Though iodine is known for its importance for the thyroid, little has been publicized about its other crucial roles. Iodine is needed in microgram amounts for the health of the thyroid on a daily basis but when you factor in the needs of all the other tissues and organs[xiv] much higher doses are needed. Iodine supports the health of many organs in the body but for the heart it is mission critical as is magnesium.  Mark Sircus Ac., OMD Director International Medical Veritas Association

    P. Pitchford, Healing with Whole Foods, Revised Edition, North Atlantic Books, 36, 1993. [ii] Journal of the American College of Nutrition, Vol. 25, No. 1, 1-11 (2006) Hypothesis: Dietary Iodine Intake in the Etiology of Cardiovascular Disease [iii] ibid [iv] Cann SAH. Hypothesis: dietary iodine intake in the etiology of cardiovascular disease. J Am Coll Nutr 2006;25(1):1-11. [v] Thyroid hormone and the cardiovascular system. Danzi S, Klein I. Minerva Endocrinol. 2004 Sep;29(3):139-50. Review. [vi] ibid [vii] ibid [viii] The Original Internist, 12(2):57-66, 2005 [ix] Health Alert, Vol. 22, No. 12 [x] Iodine deficiency in cardiovascular diseases Molnar I, Magyari M, Stief L. Orv Hetil. 1998 Aug 30;139(35):2071-3. Hungarian. [xi] Atrial Fibrillation, Arrhythmias and Iodine. West B Health Alert, June 2006, Volume 23, Issue 6 [xii] [xiii] Toll Free (800) 257-3315 [xiv] Other organs are also able to take up iodine, too, by the same transport protein as the thyroid. Research has shown that the receptor for iodine uptake is in the thyroid gland, salivary gland, parotid gland, submandibular gland, pituitary gland, pancreas, testis, mammary gland, gastric mucosa, prostate, ovary, adrenal gland, heart, thymus, lung, bladder, kidney, endometrium, and also breast, ovary and colon and the lacrimal gland The ovaries hold the second highest concentration of iodine, after the thyroid.? The breasts also have a high concentration of iodine. Most secretions in the body, whether gastric, nasal, tears, sweat, etc., have iodine in them if sufficient iodine is present in the body.




    Middle Eastern herb shows potential against pancreatic cancer

    An extract from the Middle Eastern herb Nigella sativa may not only stop the growth of pancreatic cancer, but inhibit the development of the tumours, suggest new results from the US.

    Thymoquinone, the major constituent of the herb’s oil, was found to have anti-inflammatory activity resulting in lower levels of inflammatory compounds linked to pancreatic cancer, according to findings presented at the American Association for Cancer Research (AACR) 100th Annual Meeting 2009 in Denver.

    The study findings, which have been accepted for publication in the Oxford journal Hepatopancreatobiliary (HPB), suggest that, if future studies back up the early promise, the herb extract could offer potential benefits to people with chronic pancreatitis or those at risk of development or recurrence of pancreatic cancer.

    The seed and oil of Nigella sativa have been used extensively in traditional medicine in many Middle Eastern and Asian countries, said the researchers, for the treatment of a range of conditions, including some immune and inflammatory disorders. “These are very exciting and novel results,” said lead researcher Hwyda Arafat, MD, PhD, from Thomas Jefferson University. “These potent effects show promise for the herb as a potential preventive and therapeutic strategy for pancreatic cancer. More importantly, the herb and oil are safe when used moderately, and have been used for thousands of years without reported toxic effects,” she added. According to the US National Cancer Institute almost 38,000 new cases of pancreatic cancer are diagnosed every year in the US, with almost 34,000 deaths from the disease. British charity Cancer Research UK states that the pancreatic cancer has a poor prognosis overall since most cases are diagnosed quite late. Indeed, only one in every 50 cases will still be living five years after diagnosis, highlighting the importance of prevention for this type of cancer. Dr Arafat told that his team first reported the potential anti-cancer benefits of the herb last year at the Digestive Disease week in San Diego. “This year, we’re showing the anti-inflammatory activities and the effect of treating animals with xenografts of human pancreatic cancer,” she said. “So, yes, you can consider this as the first (or second) report about the anticancerous effect of NS in pancreatic cancer by our group. To my knowledge, no one else published about NS in pancreatic cancer.”


    The herb is available on many websites, according to Dr Arafat. “There are few websites that sell good product that is well manufactured and packed. So, it is available,” she explained.

    Study details

    The earlier results showed that thymoquinone could inhibit compounds called histone deacetylases (HDACs), which play a role in gene expression and have been linked to cancer progression. For the new study, Dr Arafat and her colleagues compared the anti-inflammatory properties of thymoquinone with trichostatin A, a known HDAC inhibitor previously reported to improve inflammation-associated cancers. Using pancreatic ductal adenocarcinoma (PDA) cells pre-treated with the cytokine TNF-alpha to induce inflammation, the researchers report that the Nigella sativa extract could almost completely inhibit the expression of several inflammatory cytokines, including TNF-alpha, interleukin-1beta (IL-1b), IL-8, Cox-2 and MCP-1. Moreover, the effect was superior to that observed from trichostatin A. Furthermore, when animal with pancreatic cancer were given thymoquinone, 67 per cent of the tumours significantly shrank, with corresponding levels of pro-inflammatory cytokines significantly reduced.

    On-going study

    Dr Arafat confirmed that this remains a very active area of investigation. She is currently in the process of attaining funding for a “more aggressive program to get more information from preclinical studies”. Once funding is in the place, the researchers would “actively proceed to a phase I clinical trial. I’m currently in discussions with the medical oncologist to write a clinical trial for a small number of patients. After we obtain some preliminary data, we can then proceed to bigger trials for either prevention or therapy,” he said.



    Protective effect of Nigella sativa seeds against lead-induced hepatorenal damage in male rats.

    Nigella sativa seeds— Black Seed


    Pak J Biol Sci. 2007 Sep 1;10(17):2809-16

    Authors: Farrag AR, Mahdy KA, Abdel Rahman GH, Osfor MM

    Heavy metals are widely distributed in the environment and some of them occur in food, water, air and tissues even in the absence of occupational exposure. Among of these lead, (Pb) is a hazardous substance to human and animals. The present study was carried out to investigate the possible protective effect of co-administered Nigella sativa seeds on lead acetate-induced rats’ toxicity in particularly on liver and kidney. Thirty-six male rats were divided into six groups, 6 rats each. The first group was served as a control, while the second group was fed on the basal diet with Nigella sativa addition, whereas the other groups contained lead acetate (10 and 20% of LD50) with and without Nigella sativa supplementation for six weeks. At the end of the feeding period, rats were fasted over night and anesthetized and blood and tissue samples were taken for biochemical and histopathological studies. The results of this study revealed that lead acetate caused significant elevations in AST, urea, creatinine, total cholesterol and triglycerides in serum. Lead treatment also produced significant decrease in serum total protein and albumin. Histopathological observations showed severe damage in the liver and kidneys. Its damaged areas were measured using Image analyzer. Combined treatment of lead-exposed animals with Nigella sativa showed marked improvement in both biochemical and histopathological findings as well as reduction in the damaged areas. These experimental results strongly indicate the protective effect of Nigella sativa against toxic effect of lead on liver and kidney tissues.

    PMID: 19090181 [PubMed – indexed for MEDLINE]

    Nigella sativa relieves the deleterious effects of ischemia reperfusion injury on liver.

    World J Gastroenterol. 2008 Sep 7;14(33):5204-9

    Authors: Yildiz F, Coban S, Terzi A, Ates M, Aksoy N, Cakir H, Ocak AR, Bitiren M

    AIM: To determine whether Nigella sativa prevents hepatic ischemia-reperfusion injury to the liver. METHODS: Thirty rats were divided into three groups as sham (Group 1), control (Group 2), and Nigella sativa (NS) treatment group (Group 3). All rats underwent hepatic ischemia (is a restriction in blood supply, generally due to factors in the blood vessels, with resultant damage or dysfunction of tissue) for 45 min followed by 60 min period of reperfusion. Rats were intraperitoneally infused with only 0.9% saline solution in group 2. Rats in group 3 received NS (0.2 mL/kg) intraperitoneally, before ischemia and before reperfusion. Blood samples and liver tissues were harvested from the rats, and then the rats were sacrificed. Serum aspartate aminotransferase (AST), alanine aminotransferase (ALT), and lactate dehydrogenase (LDH) levels were determined. Total antioxidant capacity (TAC), catalase (CAT), total oxidative status (TOS), oxidative stress index (OSI) and myeloperoxidase (MPO) in hepatic tissue were measured. Also liver tissue histopathology was evaluated by light microscopy. RESULTS: The levels of liver enzymes in group 3 were significantly lower than those in the group 2. TAC in liver tissue was significantly higher in group 3 than in group 2. TOS, OSI and MPO in hepatic tissue were significantly lower in group 3 than the group 2. Histological tissue damage was milder in the NS treatment group than that in the control group. CONCLUSION: Our results suggest that Nigella sativa treatment protects the rat liver against to hepatic ischemia-reperfusion injury.

    Nigella sativa oil for prevention of chronic cyclosporine nephrotoxicity: an experimental model.

    Nigella sativa oil for prevention of chronic cyclosporine nephrotoxicity: an experimental model.

    Am J Nephrol. 2008;28(3):517-22

    Authors: Uz E, Bayrak O, Uz E, Kaya A, Bayrak R, Uz B, Turgut FH, Bavbek N, Kanbay M, Akcay A

    Nephrotoxicity is the main secondary effect of cyclosporine A (CsA) treatment. The antioxidant action of Nigella sativa oil (NSO) may explain the protective effect of these agents against various hepatotoxic and nephrotoxic models in vivo and in vitro. This study was designed to investigate the possible protective effects of NSO, in prevention of chronic CsA-induced nephrotoxicity in rats. Animals were randomly divided into four experimental groups: the control group received sunflower oil, the other groups were treated with CsA (25 mg/kg/day b.w. orally) or NSO (2 ml/kg orally) or CsA + NSO, respectively. Urine and serum creatinine levels, tissue superoxide dismutase, glutathione peroxidase and catalase enzyme activities, and nitric oxide and malondialdehyde levels were measured, and histological examination was performed. In our study, CsA caused a significant deterioration in the renal function, morphology and gave rise to severe oxidative stress in the kidney. NSO significantly improved the functional and histological parameters and attenuated the oxidative stress induced by CsA. In conclusion, our study demonstrated for the first time that NSO protects kidney tissue against oxygen free radicals, preventing renal dysfunction and morphological abnormalities associated with chronic CsA administration.

    PMID: 18223305 [PubMed – indexed for MEDLINE]


    Nigella sativa inhibits intestinal glucose absorption and improves glucose tolerance in rats.

    J Ethnopharmacol. 2009 Jan 30;121(3):419-24

    Authors: Meddah B, Ducroc R, El Abbes Faouzi M, Eto B, Mahraoui L, Benhaddou-Andaloussi A, Martineau LC, Cherrah Y, Haddad PS

    AIM OF THE STUDY: Nigella sativa L. (Ranunculaceae) seeds have been used traditionally for centuries, notably for treating diabetes. MATERIALS AND METHODS: We studied the effects of the crude aqueous extract of Nigella sativa seeds on intestinal glucose absorption in vitro using a short-circuit current technique and in vivo using an oral glucose tolerance test. RESULTS: The aqueous extract of Nigella sativa (0.1 pg/ml to 100 ng/ml) exerted dose-dependent inhibition of sodium-dependent glucose transport across isolated rat jejunum. Maximal inhibition exceeded 80% and IC50 was close to 10 pg/ml. An oral glucose tolerance test was carried out in rats after the initial dose and after a 6-week treatment of Nigella sativa (2 g/(kg day)), and compared to metformin (300 mg/(kg day)). Chronic Nigella sativa treatment improved glucose tolerance as efficiently as metformin. Nigella sativa and metformin also reduced body weight without any toxic effect. CONCLUSIONS: To our knowledge, this is the first demonstration that Nigella sativa directly inhibits the electrogenic intestinal absorption of glucose in vitro. Together with the observed improvement of glucose tolerance and body weight in rats after chronic oral administration in vivo, these effects further validate the traditional use of Nigella sativa seeds against diabetes.

    PMID: 19061948 [PubMed – indexed for MEDLINE]



    Take 1 tsp of ground Black Seed and powder it fine in a blender ….then add this honey about 3 tablespoons and add 1 cap of brandy…..blend til smooth may take about 5-8 minutes


    Add to a glass jar and use 1 tsp increments…use it 1-3 times a day if ill with different conditions…will strengthen the system and give added materials to the body to rebuild and restore the system




    MRSA Recovery

    Effect of a glutamine-supplemented diet on response to methicillin-resistant Staphylococcus aureus infection in mice.
    Suzuki I, Matsumoto Y, Adjei AA, Asato L, Shinjo S, Yamamoto S.

    Department of Food and Nutrition, Kumamoto Women’s University, Japan.

    The following study was undertaken to determine whether dietary supplementation with glutamine can be used to modulate the immune response following challenge with methicillin-resistant Staphylococcus aureus (MRSA) organisms in mice. Thirty BALB/c female mice were randomized into 3 groups: group A (n = 10) were fed 20% casein diet (control), whereas the mice in Groups B (n = 10) and C (n = 10) were given 20% casein diet supplemented with 2 and 4% glutamine, respectively. The diets were made isonitrogenous by glycine and alanine supplementation. On the 10th day on these treatments, each mouse was challenged intravenously with 2 x 10(8) colony-forming units (CFU)/ml of MRSA organisms and mortality was noted for 20 days. The survival rate in Group A (20%) tended to be lower than the rates in Group B (40%), and Group C (70%). CFU values of spleen and kidney of the surviving mice 20 days post challenge were not different among the three groups (p < 0.05). The present results suggest that dietary glutamine supplementation may be effective as a nutritional immunomodulator for the recovery from MRSA infection.


    Aromatherapy oils ‘kill superbug’
    « on: December 22, 2004, 04:59:51 PM »

    Essential oils could kill the deadly MRSA hospital ‘superbug’, scientists have claimed.  University of Manchester researchers found three of the oils, usually used in aromatherapy, destroyed MRSA and E.coli bacteria in two minutes. They suggest the oils could be blended into soaps and shampoos which could be used in hospitals to stop the spread of the superbug. Hospital-acquired infections, such as MRSA, kill an estimated 5,000 a year. The Manchester study was triggered when complementary medicine specialists at Christie Cancer Hospital asked university researchers to test essential oils.  Our research shows a very practical application which could be of enormous benefit to the NHS and its patients
    Jacqui Stringer, Christie Hospital, Manchester They wanted to ensure they could not harm the patients, whose immune systems are weakened by the treatments. Dr Peter Warn, who carried out the research, said: “When I tested the oils in the lab, absolutely nothing grew. Rather than stimulating bacteria and fungi, the oils killed them off.” Soaps and shampoos The team then tested 40 essential oils against 10 of the most infectious agents found in hospitals, including MRSA (methicillin-resistant staphylococcus aureus).  Two of the oils were found to kill MRSA and E.coli almost instantly, while a third was found to act over a longer period of time. However, the researchers say they are unable to reveal which oils carry benefits because of commercial sensitivities. MRSA is often carried in patients’ nostrils, and is currently treated by putting disinfectant on the area to kill the bacterium – which many patients often find unpleasant. Dr Warn says the essential oils could be used to create much more pleasant inhalation therapies – which he said were likely to have a much higher success rate than the current treatment, which is only effective in around 50% of cases.” Dr Warn said: “We believe that our discovery could revolutionise the fight to combat MRSA and other superbugs.” But he said the team now needed around £30,000 in order to continue its research. Jacqui Stringer, clinical leader of complementary therapies at Christie Hospital in Manchester, instigated the oils research. She said: “Our research shows a very practical application which could be of enormous benefit to the NHS and its patients. “The reason essential oils are so effective is because they are made up of a complex mixture of chemical compounds which the MRSA and other superbug bacteria finds difficult to resist.” The Department of Health evaluates products which are claimed to prevent or treat HAIs before it permits them to be used across the NHS.



    Vapour-phase activities of essential oils against antibiotic sensitive and resistant bacteria including MRSA.
    Doran AL, Morden WE, Dunn K, Edwards-Jones V.

    School of Biology, Chemistry and Health Science, Manchester Metropolitan University, Manchester, UK.

    AIMS: To determine whether essential oil (EO) vapours could reduce surface and airborne levels of bacteria including methicillin-resistant Staphylococcus aureus (MRSA). METHODS AND RESULTS: The antibacterial activity of geranium and lemongrass EO individually and blended were evaluated over a range of concentrations by direct contact and vapour diffusion. The EO were tested in vitro against a selection of antibiotic-sensitive and -resistant bacteria, including MRSA, vancomycin-resistant Enterococci (VRE), Acinetobacter baumanii and Clostridium difficile. An EO blend containing lemongrass and geranium was used to formulate BioScent that was dispersed into the environment using the ST Pro machine. The effects were variable depending on the methods used. In a sealed box environment, MRSA growth on seeded plates was reduced by 38% after 20 h exposure to BioScent vapour. In an office environment, the ST Pro machine dispersing BioScent effected an 89% reduction of airborne bacteria in 15 h, when operated at a constant output of 100%. CONCLUSIONS: EO vapours inhibited growth of antibiotic-sensitive and -resistant bacteria in vitro and reduced surface and airborne levels of bacteria. SIGNIFICANCE AND IMPACT OF THE STUDY: Results suggest that EO vapours, particularly Bioscent, could be used as a method of air disinfection



    The effect of essential oils on methicillin-resistant Staphylococcus aureus using a dressing model.
    Edwards-Jones V, Buck R, Shawcross SG, Dawson MM, Dunn K.

    Department of Biological Sciences, the Manchester Metropolitan University, Chester Street, Manchester, M15GD, UK.

    Patchouli, tea tree, geranium, lavender essential oils and Citricidal (grapefruit seed extract) were used singly and in combination to assess their anti-bacterial activity against three strains of Staphylococcus aureus: Oxford S. aureus NCTC 6571 (Oxford strain), Epidemic methicillin-resistant S. aureus (EMRSA 15) and MRSA (untypable). The individual essential oils, extracts and combinations were impregnated into filter paper discs and placed on the surface of agar plates, pre-seeded with the appropriate strain of Staphylococcus. The effects of the vapours of the oils and oil combinations were also assessed using impregnated filter paper discs that were placed on the underside of the Petri dish lid at a distance of 8mm from the bacteria. The most inhibitory combinations of oils for each strain were used in a dressing model constructed using a four layers of dressings: the primary layer consisted of either Jelonet or TelfaClear with or without Flamazine; the second was a layer of gauze, the third a layer of Gamgee and the final layer was Crepe bandage. The oil combinations were placed in either the gauze or the Gamgee layer. This four-layered dressing was placed over the seeded agar plate, incubated for 24h at 37 degrees C and the zones of inhibition measured. All experiments were repeated on three separate occasions. No anti-bacterial effects were observed when Flamazine was smeared on the gauze in the dressing model. When Telfaclear was used as the primary layer in the dressing model compared to Jelonet, greater zones of inhibition were observed. A combination of Citricidal and geranium oil showed the greatest-anti-bacterial effects against MRSA, whilst a combination of geranium and tea tree oil was most active against the methicillin-sensitive S. aureus (Oxford strain). This study demonstrates the potential of essential oils and essential oil vapours as antibacterial agents and for use in the treatment of MRSA infection.



    March 28-2010 Workshop HerbsPlus Windsor Ontario


    • Egg Shell Calcium
    • Making a Cream or Lotion
    • Seed Milk


    Egg Shell Calcium


    “”””Make your own Egg Shell Calcium—you will need citric acid- (malic acid– optional )–egg shells—essential oil of either orange or peppermint—gelatin—xylitol Reverse osmosis or distilled water—xanthium gum –Comfrey root extract ( optional )””””

    Rinse out the egg shells thoroughly in water or give the shells an acid bath to remove the inner shell of egg

    Take your egg shells and put into a toaster oven ( or regular oven ) set the heat to about 200 fahr ( 100 cel) for about 15 minutes—then take out and put into blender and powder—add 1 tsp of citric acid—1 tsp of gelatin —1/4 tsp of xanthium gum— ¼ cup of water ( you can add more if you like it thinner or less you determine how you want it —add 1 tsp of xylitol—and add 1-2 drops of either the essential oil of orange or peppermint—and add 1 0unce of comfrey extract ( the last one is optional )

    Special Note —if you want to make it with magnesium then add ½ of magnesium oxide to the proportion of calcium ( egg shells that are powdered ) this will give you a 2:1 ratio as you would normally use to absorb the calcium more effectively) DO NOT ADD VITAMIN D— Vitamin D and Magnesium have a negating effect with each other—take your Vitamin D separate and at separate times


    Use 1 tsp before bed at night—refrigerate the mix will cause it to become hard so leave out on counter or in cabinet

    Never take calcium with anything ( supplements —pharmaceuticals—food ) this will impede absorption and block digestion—as well wait 2 hours before consuming anything supplement or pharmaceutical


    Eggshell calcium in the prevention and treatment of osteoporosis.
    Rovenský J, Stancíková M, Masaryk P, Svík K, Istok R.

    National Institute of Rheumatic Diseases, Piestany, Slovak Republic.

    In this paper the most significant biological and clinical aspects of a biopreparation made of chicken eggshells are reviewed. Eggshell powder is a natural source of calcium and other elements (e.g. strontium and fluorine) which may have a positive effect on bone metabolism. Experimental and clinical studies performed to date have shown a number of positive properties of eggshell powder, such as antirachitic effects in rats and humans. A positive effect was observed on bone density in animal models of postmenopausal osteoporosis in ovariectomized female rats. In vitro eggshell powder stimulates chondrocyte differentiation and cartilage growth. Clinical studies in postmenopausal women and women with senile osteoporosis showed that eggshell powder reduces pain and osteoresorption and increases mobility and bone density or arrests its loss. The bioavailability of calcium from this source, as tested in piglets, was similar or better than that of food grade purified calcium carbonate. Clinical and experimental studies showed that eggshell powder has positive effects on bone and cartilage and that it is suitable in the prevention and treatment of osteoporosis.

    PMID: 15018022 [PubMed – indexed for MEDLINE]


    [Hen’s eggshell calcium.]
    Masuda Y.-R&D Division, Q.P. Corporation, Japan.

    In Japan, insufficient calcium (Ca) intake is serious problem for health which may be associated with the high prevalence of osteoporosis among the aged. The intake of most nutrients has been sufficient, however, the Ca intake has never been sufficient. Eggshell Ca has as much as 38% of Ca and low phosphorus content. Eggshell Ca was more soluble than Ca carbonate and was as much as milk products. Eggshell Ca has been shown to exhibit higher absorptivity and availability than Ca carbonate. Furthermore, it has been reported that eggshell Ca is more effective in increasing bone mineral density in ovariectomized osteoporotic rats. These results suggest that eggshell Ca could be beneficial for bone and we propose Ca fortified foods which contain eggshell Ca as a nutraceutical.

    PMID: 15632478 [PubMed – indexed for MEDLINE]


    The health benefits of calcium citrate malate: a review of the supporting science.
    Reinwald S, Weaver CM, Kester JJ.

    Department of Foods and Nutrition, Purdue University, West Lafayette, IN 47907, USA.

    There has been considerable investigation into the health benefits of calcium citrate malate (CCM) since it was first patented in the late 1980s. This chapter is a comprehensive summary of the supporting science and available evidence on the bioavailability and health benefits of consuming CCM. It highlights the important roles that CCM can play during various life stages. CCM has been shown to facilitate calcium retention and bone accrual in children and adolescents. In adults, it effectively promotes the consolidation and maintenance of bone mass. In conjunction with vitamin D, CCM also decreases bone fracture risk in the elderly, slows the rate of bone loss in old age, and is of benefit to the health and well-being of postmenopausal women. CCM is exceptional in that it confers many unique benefits that go beyond bone health. Unlike other calcium sources that necessitate supplementation be in conjunction with a meal to ensure an appreciable benefit is derived, CCM can be consumed with or without food and delivers a significant nutritional benefit to individuals of all ages. The chemistry of CCM makes it a particularly beneficial calcium source for individuals with hypochlorydia or achlorydia, which generally includes the elderly and those on medications that decrease gastric acid secretion. CCM is also recognized as a calcium source that does not increase the risk of kidney stones, and in fact it protects against stone-forming potential. The versatile nature of CCM makes it a convenient and practical calcium salt for use in moist foods and beverages. The major factor that may preclude selection of CCM as a preferred calcium source is the higher cost compared to other sources of calcium commonly used for fortification (e.g., calcium carbonate and tricalcium phosphate). However, formation of CCM directly within beverages or other fluid foods and/or preparations, and the addition of a concentrated CCM solution or slurry, are relatively cost-effective methods by which CCM can be incorporated into finished food and beverage products.

    PMID: 18291308 [PubMed – indexed for MEDLINE]

    Making a Cream or Lotion

    Things you will need—Fat of choice—oil—Citric acid—Essential oils—water—alcohol ( vodka—gin—rum—or anything that pleases the senses that is clear ( the coloured alcohols may have contaminants that we would like to avoid )—Bees Wax what you will do is get a glass jar—and add your fat in here ( coconut oil—shea—palm—cocoa—butter) 3 tablespoon ( you can go more or less depending on your amount you are wanting) add 2 ounces of oil ( avocado—olive—almond—apricot—sunflower—sesame seed oil are a few you can use )and place in the pot of water—turn on the stove and allow the pot with water to boil as it boils add slices of bees wax to the glass jar of oil—start out with a tablespoon this will mix with the oil that is already there add 4-8 drops of the essential oil of choice ( we will be using lavender and rosewood) while this is heating take a glass container and add 2 tablespoon of water and add ½ tsp of citric acid and mix well till everything is dissolved—put contents in blender and add another 4-8 drops of the same essential oils—add ½ ounce of alcohol to this as well ( you will need this so that the fat or cream or lotion can penetrate the skin ) or take a tincture or alcohol extract of any floral you have made ( jasmine –marigold—chamomile –st johns wort ( to name a few )–when the oil and bees wax is fused and it is all liquid put this in the blender while it is hot—then as it is in the blender proceed to blend at high speed—due this til either everything is completely fused –observe the density—if it is the way you want it then pour into a GLASS container  ( do not use plastics at all –If this solution is hot and you put it in a plastic container the hot oil will absorb the toxins in the plastic and the xenoestrogen which are cancer causing so use GLASS!!!)

    if it is not thick enough while the solution is hot use some more wax and added to the blending so it will thicken this or if you want it thinner just add more oil—eyeball this so you can see how you want it—remember that when this cools this will thicken so don’t over do it either way—


    Essential oils suggestion and uses-

    Lavender—soothing agent, skin conditioner, astringent

    Juniper–astringent, skin detoxifier, deodorant, soothing agent

    Geranium–skin refresher, astringent ( anti MRSA )

    Cinnamon–strong antiseptic, it has a cleansing effect.– skin conditioner, deodorant
    Cypress–antiseptic, astringent, deodorant,

    FFAll Essential Oils are high In antioxidant and Anti Aging effects cellularly




    Seed Milk


    You will need seeds or nuts of choice—1-2 tablespoon of favourite nut or seed(s) if you want to make a combo–allow to soak over night and next day add all of the components –water and seed in blender—you will need ¼ tsp of xanthium gum—and honey or maple syrup or xylitol ( you may not need these at all —it will be a preference to use or not to use ) start the blending and once it gets to a purred or smooth paste then add your water to it slowly—if you want to add your sweetener you can as well—it will be up to you—keep adding the water til you reach the top—allow for expansion so do not over fill the blender

    Allow to blend at high speed for about 5 minutes

    When done BOTTLE IN GLASS- this is all enzyme active ( live, living food)

    Use this in any form you see fit —as a milk beverage—add whey to this and make a protein shake—add it to your honey mixes—add it to your cocoa making recipes—this is but one variation—you can add cocoa to this to make a cocoa seed milk—you can add 1 drop of an essential oil with this like orange or ginger—peppermint—you can add coconut milk or cream to increase fat and make it more smoother


    Nutritional Value of some Nuts and Seeds—

    Almond (mg of Substance per 100 grams)

    Aldehydes: Benzaldehyde

    Amino Acids: 20,000—Alanine— Aspartic Acid—Arginine

    Carbohydrates: 20,000—

    Enzymes: Beta-Glucosidase

    Fatty Acids: 52,000—Stearic Acid-2,600 Linoleic Acid-8,840

    Oleic Acid–40,560 Alpha-Linolenic Acid–400

    Glucosides: Laetrile

    Minerals: Magnesium 270 Manganese 2 Boron Potassium-732

    Copper 1 Iron-4 Phosphorus 520 Calcium-234

    Zinc 3

    Organic Acids: Oxalic Acid Prussic Acid

    Quinones: Coenzyme Q9 -0.63 Coenzyme Q10–1.4

    Vitamins: Vitamin B1-0.2 Vitamin B2-0.8 Vitamin B5–0.5 Vitamin B6–0.1

    Vitamin B3 Vitamin E


    Walnut (mg of Substance per 100 grams)

    Amino Acids: 15,230 Tryptophan- 170 Threonine–596 Isoleucine–625

    Leucine–1,170 Lysine—424 Methionine–236 Cysteine—208 Phenylalanine—711 Tyrosine–406

    Carbohydrates: 13,710

    Fatty Acids: 62,235 Sterols–72 Cholesterol–NIL

    Phytosterols–72 Saturated–6,126 Palmitic Acid–4,404 Stearic Acid–1,659

    Unsaturated–56,109 Monounsaturated–8,933

    Oleic Acid–8,799 – Gadoleic Acid-134 Omega-6–38,095 Linoleic Acid-8,095

    Omega-3–9,081 Alpha-Linolenic Acid–9,081

    Minerals: 1,780—Iron-2.91 Magnesium–158 Potassium—441 Calcium-104 Copper–1.4 Manganese –3.414

    Phosphorus–346 Zinc–2.7 Selenium–0.0046 Sodium–2.0 Zinc–3.09 Copper–1.586

    Quinones: Coenzyme Q10–1.9

    Vitamins: Vitamin C–1.3 Vitamin B1–0.341 Vitamin B2–0.15 Vitamin B6–0.537 Vitamin B3-1.909 Vitamin B5–0.57 Folic Acid–0.098 Vitamin E–2.942


    Hazel Nut (mg of Substance per 100 grams)


    Amino Acids: 13,000

    Carbohydrates: 15,000

    Lipids: 63,000

    Minerals: Boron Zinc–2.4 Manganese—2 Calcium–188

    Magnesium—285 Phosphorus–312

    Copper–1.5 Iron– 3.3 Potassium–445

    Quinones: Coenzyme Q10–1.7

    Vitamins: Biotin Vitamin C—1 Vitamin B2–0.1 Vitamin B3–1.1

    Vitamin B5–1.1 Vitamin B1

    Vitamin B6–0.6 Vitamin E


    Ramirez Work Shop ( Phoenix, Arizona )





    Vitamin C could reduce inflammation

    08/03/2006- A diet rich in sources of vitamin C could cut the level of

    markers for inflammation by 45 per cent, a result that needs verifying

    by supplementation studies, says a new study. Consumers have a positive image of vitamin C, with public perception linking the vitamin to improved immune system health. The new cross-sectional study, published in this month’s American Journal of Clinical Nutrition (Vol. 83, pp. 567-574), examined 3258 men aged between 60 and 69 with no history of diabetes or cardiovascular disease. A food-frequency questionnaire was used to quantify vitamin C intake from dietary and supplemental sources, and related to blood levels of certain markers linked to inflammation: C-reactive protein (CRP) and tissue plasminogen activator (t-PA). “Plasma vitamin C, fruit intake, and dietary vitamin C intake were significantly and inversely associated with mean concentrations of C-reactive protein, an acute phase reactant, and t-PA antigen, a marker of endothelial dysfunction,” wrote lead author Goya Wannamethee from the Royal Free and University College Medical School, London. High blood levels of vitamin C were associated with a 45 per cent reduced risk of inflammation (with respect to CRP levels), and high fruit intake was related to a 25 per cent reduced risk of inflammation. “Plasma (but not dietary) vitamin C also showed inverse associations with both fibrongen concentrations and blood viscosity,” reported Wannamethee. In an accompanying editorial (Vol. 83, pp. 525-526), Ishwarlal Jialal and Uma Singh from the University of California Davis Medical Center, said: “It is important to emphasize that theirs was a cross-sectional study and not a randomized placebo-based clinical trial, and thus the authors conclusion is not firm and cannot be used for policy guidelines.” The editorial also pointed out that the study was only focused on elderly white men and thus could not be generalized for other races, women, and age groups. Jialal and Singh also questioned the use of t-PA as a measure of endothelial inflammation. “It is not clear whether there is indeed a relation between vitamin C and biomarkers of endothelial function, because the authors did not show a correlation between vitamin C and von Willebrand factor, another biomarker.” Both commentators stressed that previous clinical trials (with diabetics, smokers and healthy men) had not reported an anti-inflammatory effect from vitamin C supplementation. In contrast, intravenous vitamin C trials did report an improvement in endothelial function. “Much further research in a dose-response is required to ascertain whether oral vitamin C supplementation is anti-inflammatory and whether it improves endothelial dysfunction,” concluded Jialal and Singh. The recommended daily intake of the vitamin in Europe is 60 mg. In the US, men are recommended to consume 90 mg per day, and women 75 mg per day. Lactic acid Reduction Solutions: One recommended by Dr. Reich, “Calcium and Vitamin D Deficiency, The Theory and Clinical Work of Dr. Carl Reich,” which I had the privilege of editing for The Arthritis Fund, is calcium-magnesium. Calcium and magnesium combine with lactic acid, neutralizing the negative effect of excess lactic acid, normalizing pH, and normalizing breathing for asthma, emotional disturbances, and restoring the ill health of people in many disease conditions. Malic acid supplements, an acid found in food, in apples and other fruit, and produced by the citric acid cycle in the human body itself, has been written about by Holzschlag as “reducing” the effects of excess lactic acid. Drs. Hyde, Cheney, and Goldstein have used it in their practice with CFS to improve energy and reduce pain. The reason for greater energy is made clear by Lehninger. It doesn’t neutralize lactic acid build-up directly. Energy production uses another pathway with malic acid. Szent-Gyorgyi found that malic acid kicks red muscle into using oxygen to produce its energy rather than anaerobic ways of doing it. Rather than reducing the effects of lactic acid, malic acid gives a signal to the mitochondria to use oxygen to burn fat as fuel or to use oxygen to burn glucose as energy. Red muscle is red because of its oxygen content. Oxygen gives muscle and blood its redness. The red blood cell abnormalities in people subject to Multiple Chemical Sensitivity and chronic fatigue may stem from inability of the RBC to carry adequate oxygen to the cells, so the cells revert to their least efficient mode of energy production, the lactic acid or alcohol pathways. Iron-copper balance synergized with molybdenum help make the RBC do its job of carrying oxygen. Mineral deficiency or mineral imbalance may help explain why RBC abnormalities exist, and, at the same time, explain why MCS people, PPS, and CFS have unusual blood gases. Either mineral deficiencies trigger abnormal breathing patterns, or abnormal breathing patterns trigger mineral deficiency. In fact, both perpetuate each other. The more hurried you are, the tenser you become, and the worse the breathing. Type A hurried rats were created by injuring the hypothalamus in Friedman and Rosenman’s experiments. Hypothalamus damage in humans is explained to my way of thinking under beriberi listings in the 1992 Merck Manual: refined sugar, white flour, or white rice causes hypothalamus damage, poliocencephalitis, weakness in the extremities and the heart, by not having enough real B1, thiamine pyrophosphate cocarboxylase and magnesium. Vitamin B1 and magnesium deficiency from refined carbohydrates may be the mineral-vitamin cause of the Type A personality to begin with if I’m right. You can become Type A just as the accountants did by just hurrying through life; you could also become that way if refined sugars and grains are staples in your diet. Type A breathing patterns worsen mineral status either through fostering overly acid conditions in the blood less than pH 7, or overly alkaline conditions over 7.4. Long term use of ascorbic acid or “vitamin C” may also lead to or worsen mineral status for one simple reason. Ascorbic acid takes both bad toxic metals out of the system and GOOD minerals at the same time. All of those circumstances suggest solutions. Change your breathing, pace yourself, and slow down. Deep breathing alone should be a part of every health program. Secondly, checking your mineral status, or taking mineral supplements may do the job to help give your cells the oxygen they need for greater energy and strength, especially calcium-magnesium. Moderating ascorbic acid use might also be warranted. Adding malic acid supplements or upping one’s intake of apples and apple products like apple cider vinegar and juice make a lot of sense. You get more oxygen and you’re no longer running on empty. You have 20 times the fuel to go on after malic acid kicks your muscles into their most efficient energy mode The body’s defenses against an increase in acidity are the bicarbonate, phosphate, and protein “buffers”, which help to neutralize the acid produced by intense exercise…Taking a sufficient quantity of sodium bicarbonate (baking soda) before high-intensity event should make the muscles and blood less acidic during the event and should enhance physical performance. Sodium citrate is another substance that should enhance performance by buffering the acidity of intense exercise….Short-term exercise can be enhanced by reducing the level of acidity. In a review of 29 studies of the effects of ingestion of sodium bicarbonate, Matson and Vu Tran (1993) concluded that the effect on performance varied between athletes, but that the greater the dosage and the shorter the exercise, the more likely that bicarbonate buffering would enhance performance. Maughan and Greenhaff (1991) concluded that ingestion of sodium bicarbonate can enhance performance of high intensity exercise lasting 1-10 minutes…Tested the effect of sodium citrate on 30-km cycling performance. Performance times averaged almost 3% faster than those in the placebo condition


    Benfotiamine is a form of Vitamin B-1 used in Germany for the treatment and prevention of diabetic health complications. Advanced Glycation Endproducts, or “AGEs” as they’re appropriately called, are the end result of the complex chemical process through which the structure of proteins is warped by exposure to sugars or by other, much more reactive molecules. AGE chemistry is the cause of the “browning” you see when you roast a chicken or make toast, but the same “browning” chemistry is at work in your body every day of your life. In your arteries. In your kidneys. In your heart, your eyes, your skin, your nerves. In every cell, the sugar that your body uses for fuel is busily at work at this very moment, caramelizing your body through exactly the same chemical processes that caramelize onions or peanut brittle. Glycation math is simple: more sugar equals more AGEd proteins. As a result, people with diabetes begin to feel the effects of glycation at much younger ages than do people with more normal blood sugar levels. Watching people with diabetes age is like watching “normal” aging played on fast-forward. Slowly, imperceptibly, AGE reactions create chemical handcuffs, which gum up your proteins, deactivate your enzymes, trigger unhealthy biochemical signaling in your cells, and damage your DNA. Aging you. Make that: AGEing you. Two Ways to AGE There are two major ways that AGEs can form inside the body. One way is through a simple series of chemical reactions known as the “Maillard Pathway,” known from food chemistry for a century. But more recently, scientists have come to understand another pathway of AGE formation – a distinctly biological pathway, which only occurs within your cells because of the body’s metabolism of carbohydrates. When blood sugar levels rise, some key kinds of cell – including- nerve cells (neurons) and the cells that make up the fine blood cells of the retina of the eye and the filtering units (glomeruli) of the kidney – are also flooded with glucose. The resulting high sugar levels within these cells cause a logjam in the normal cellular metabolism of glucose. This backlog results in a buildup within the cell of super-reactive glucose-metabolic intermediates known as triosephosphates. And once that happens, the excess triosephosphates attack the surrounding proteins, lipids, and DNA, causing AGE damage from within the heart of the cell. It’s these cells are thus the most vulnerable to the complications of diabetes. Drugs do exist which can inhibit the formation of AGE, but none are available on the market as yet, and one of the most promising candidate (aminoguanidine) has shown signs of toxicity in human trials and appears to have been abandoned by its developers. On the other hand, some companies are selling supplements are marketed as “AGE-inhibitors.” But while many of the herbs and other nutrients may be valuable, and many even inhibit AGEing in a test tube, there’s no evidence that most of these “AGE-blocking” ingredients have any effect on AGEing in your body at the dosages used. Examples include thyme extract, inositol, acetyl-Lcarnitine, taurine, and a whole host of antioxidants (including nacetyl- cysteine (NAC) and flavonoids, such as quercetin and resveratrol). Special Note_ these, above mentioned supplements so work on retarding the age, issues as a result of free radical damge , but the have to be taken at a high end and throughout the day, or there effect is not that good _The power of Benfotiamine to improve vibratory perception threshold and nerve conduction velocity have been confirmed in other trials. Clinical trials have also shown that Benfotiamine supports nerve function in diabetics as measured by many other methods. For instance, Benfotiamine users experience a 50% reduction in diabetic nerve pain, along with an increased ability of the nerves to detect an electrical current, respond to electrical stimulation, and regulate the heartbeat Similarly, Benfotiamine prevents this loss of control from happening in the first place in diabetic dogs. In another human clinical trial, a B-vitamin combination using Benfotiamine as its thiamin source was put head-to-head with a Bcomplex supplement that included a megadose of conventional thiamin. Benfotiamine proved its effectiveness on several of these key parameters, while the standard thiamin pill failed. These benefits are not due to changes in blood sugar levels (either fasting, or after a meal, or averaged over several months (as measured by HbA1c), or improvements in metabolic benchmarks. They are the direct results of Benfotiamine’s AGE-fighting, metabolic-balancing powers. Benfotiamine in Other Vulnerable Tissues More recently, new studies have begun to document Benfotiamine’s ability to shield other tissues from AGE damage. One just-published study tested the ability of thiamin and Benfotiamine to protect diabetic rodents’ retinas from the ravages of AGE. The researchers then gave one group of diabetic rodents Benfotiamine supplements, and left another group unsupplemented, keeping a third group of nondiabetic animals as a control group. Nine months later, they examined the animals’ eyes, testing the level of AGE in their retinas, examining metabolic abnormalities of the cells, and looking for acellular capillaries (the dead husks left behind when the cells of the tiny blood vessels of the eye die). Benfotiamine supplements normalized AGE levels in the diabetics’ retina, as well as several key metabolic parameters within the diabetic animals’ cells – without influencing body weight or blood sugar (as measured by HbA1c). More importantly, Benfotiamine prevented the AGE-associated retinal damage. After nine months of diabetes, diabetic animals had suffered three times as many acellular capillaries as were found in healthy animals. But with the protection afforded by Benfotiamine, the number of acellular capillaries in the supplemented diabetics was indistinguishable from that of their normal, healthy cousins! And there’s another AGE-related disease that researchers believe Benfotiamine may fight: the loss of kidney function which accompanies “normal” aging, and which is accelerated by diabetes. Dr. Paul Thornalley of the University of Essex has just completed a study designed to see if Benfotiamine will protect diabetic rodents against kidney damage. While the results have not yet been published, Dr. Thornalley has indicated that both megadose thiamin and Benfotiamine caused clear-cut reductions in the leakage of protein – with Benfotiamine showing itself to be the superior intervention. A second study is now underway to see if Benfotiamine will actually improve kidney function in diabetic animals with pre-existing kidney damage, as it has already been shown to do in the nerves of diabetic animals and humans


    Did you know that this herb/spice is the equivalent as nitroglycerin that they use for heart patients, but without the side effects??? amazing eh, how God and Creation…have a way of knowing what the actual programs and chemicals really work for us and keep us alive…. Here are some of the other actions that Galangal has…. Main Actions Other Actions

    · lowers blood pressure · relieves pain

    · kills bacteria · kills insects

    · kills fungi · relieves spasms

    · kills candida · antioxidant

    · reduces pain Rhizo me

    This can be made into a tea…a tincture…..taken as a spice….mixed with

    food…..or blended with wine….taken with honey….and a host of other

    combo’s as well as uses.

    Here is a quote fro the past: “Whoever has heart pain and is weak in the heart should instantly eat enough galangal, and he or she will be well again” is it not amazing that for all our expertise and our technology, that the past can still give us a blast as to what really has been tried and true…..and did you also know that they tied “gastric distresses” to heart conditions and that galangal addressed successfully….this is really a profound statement…that the foods that linger in the intestines can cause a heart condition ….hmmm….foods that can linger in the gut…GMO’s….GE’s….SOY ( really bad for this) BEANS….high dense insoluble fibers…..anything fermentable…wow!!!! and this was in the 12th century…makes you feel sort of humble eh!??imagine if the Doctors and Dieticians today could actually be aware of what they knew in the past, you think we would have heart issues?? here is another tidbit on Galangal “Antifungal:Research indicates that galangal is distinctly effective against Candida albicans.” again this ties with intestinal debris not moving and fermenting, creating an excess sugar which will eventually bring out fungus which feeds on sugar, to try to balance the system from excess sugar…. here is what the chinese found out as well ” had an antibacterial action against a number of pathogens, including anthrax”…..So here you have it….a herb/spice…that is a pharmacy all it’s own….next time you see this ….pick it up and start a tea … has other qualities as well….it can have aphrodisiac properties ….hmmm heart health….intestinal fortitude…and sex…what more can one ask for!!!


    Inositol is necessary for the formation of lecithin and functions closely with a B complex vitamin, Choline. Since it is not essential in the human diet, it cannot be considered a vitamin. Inositol is a fundamental ingredient of cell membranes and is necessary for proper function of nerves, brain, and muscles in the body. Inositol works in conjunction with folacin, Vitamins B-6 and B-12, choline, betaine, and methionine to prevent the accumulation of fats in the liver. It exists as the fiber component phytic acid, which has been investigated for its anti-cancer properties. Inositol is primarily used in the treatment of liver problems, depression, panic disorder, and diabetes. It also aids in the breakdown of fats, helps in the reduction of blood cholesterol, and helps to prevent thinning hair. A diet low in Inositol may result in deficiency symptoms that culminate in high blood cholesterol, constipation, eczema, and hair loss. Neurotransmitters such as seratonin in the brain depend on Inositol to function properly. Low levels of this nutrient may result in depression and some research has shown that increased levels of Inositol appear to be a promising treatment for depression. According to recent research, the abundance of Inositol in fiber may explain in part why high fiber diets are often associated with a lower incidence of certain cancers. Although promising in the treatment of depression and high blood cholesterol, there is no significant research available to support the use of Inositol for weight loss.


    By Dr. James Howenstine, MD.

    July 27, 2006

    Medical journals and textbooks typically portray iodine as an unimportant substance which should be taken in small amounts[1] because of it’s dangers. Actually approximately one third of humanity has iodine deficiency. When humans lack iodine the thyroid gland enlarges (goiter), nodules appear in the thyroid gland and over a period of time cancer may appear in a thyroid nodule. Conventional medicine treats thyroid gland enlargement with thyroid hormone without considering the possibility that the hypothyroidism and goiter may be due to lack of iodine. This failure to diagnose and treat iodine deficiency can lead to an increased risk of breast cancer and the longer the diagnosis is missed the greater the chance that breast cancer will occur. Women taking thyroid hormone appear to be twice (12.1%) as likely to develop breast cancer as women not using thyroid hormone (6..2%). Women who had taken thyroid hormone for 15 years had a 19.5% incidence of breast cancer whereas women who have only taken thyroid hormone for 5 years had only a 10% incidence of breast cancer. Why is this? The essential trace element iodine may be the most important least publicized mineral in existence. Iodine is the only element needed in hormones and in the production of hormones. The iodine containing hormones are involved in the creation of embryos, development of brain function, growth, metabolism and maintenance of body temperature. This means that proper amounts of thyroid hormone, estrogen, progesterone, testosterone, insulin, growth hormone etc. can not be made when iodine is lacking from the body. One third of all individuals on Earth are functioning with subnormal levels of iodine. Low intake of iodine is the leading cause for intellectual deficiency in the world.There is strong evidence that iodine lack predisposes to breast cancer. One out of seven women in the U.S. has deficiency of iodine proven by urine iodine screening tests (urine I less than 50 ug/L). This is the same incidence for breast cancer seen in U.S. women. Without bothering to check urine for iodine, physicians visited by a woman with a goiter or symptoms of hypothyroidism are routinely prescribing thyroid hormone therapy. Hintze et al[2] compared the results of 400ug/L of Iodine with 150ug of T4 (synthyroid) for 8 months and then four months after stopping therapy. The results clearly favored iodine therapy. Both treatments led to similar suppression in the size of the goiter. However, four months later the size of the thyroid had returned to pre-treatment levels in the group treated with T4 hormone. The group who had received iodine therapy continued to have normal sized thyroid glands four months after therapy was stopped. Several investigators have concluded that iodine lack is a probable cause for breast cancer in women. Demographic studies in Japan and Iceland revealed that both countries have a high intake of iodine and low incidences of goiter and breast cancer ( My special note this is the REAL REASON why Asian women DO NOT GET BREAST CANCER, that and utilizing Fish Bone soup, the Vitamin D that also prevents Cancer of the reproductive system, SOY encourages breast cancer ). In Mexico and Thailand where iodine intake is low there is a high incidence of goiter and breast cancer.[8] Thyroid gland size measured by ultrasound is significantly larger[9] in Irish women with breast cancer than control women. Administration of thyroid hormone to iodine deficient women appears to increase the risk of developing breast cancer. In a group of women undergoing screening mammograms the incidence of breast cancer[10] was twice as high in the women taking thyroid hormone. for hypothyroidism (probably caused by iodine lack) than in women not taking thyroid supplements. The mean incidence was 6.2% in controls and 12.1% in women on thyroid hormones. The incidence of breast cancer was twice as high in women taking thyroid hormone for more than 15 years (19.5%) compared to those on thyroid hormones for only 5 years (10%). In the state of Michigan, during a period of iodine supplementation in bread (1924-1951) the prevalence of goiter diminished from 38.6% to 1.4%. Of interest the incidence of breast cancer remained unchanged during this time frame. This information was used to suggest that iodine supplementation had no effect on the incidence of breast cancer. However, Ghent and Eskin were able to show in women and female rats that the amount of iodine needed to protect against fibrocystic disease of the breast and breast cancer was at least 20 to 40 times greater[11] than the iodine needed to control goiter. In the 1960s mandated iodine containing dough was equivalent to the RDA of 150 ug per slice of bread. At that time the incidence of breast cancer was only 1 in 20.[12] In the past 20 years the use of iodine supplementation in bread was eliminated and a goiter producing substance toxic to the thyroid gland (bromine) was introduced as replacement for iodine. The risk for breast cancer is now 1 in 8 and this risk is increasing by one percent[13] each year. The decision to replace iodine in an iodine deficient population with a goitrogen was illogical lacking in common sense. The damaging effects of bromine on thyroid tissue also appears to contribute to the development of auto-immune diseases in the thyroid gland (Hashimoto’s thyroiditis). Now the next part is extremely important, as to the why iodine is required for breast health….. ( my special note ) The mammary glands have a trapping system for iodine similar to that of the thyroid gland. The breasts effectively compete with the thyroid gland for ingested iodine. This distribution of iodine to both breast and thyroid gland in pubertal girls explains why goiter is 6 times more common in girls than pubertal boys. The disappearance of iodine into breast tissue in women leads to decreased ability to supply the thyroid gland with an adequate amount of iodine. The development of a goiter in young girls indicates deficient distribution of iodine to both breast and thyroid tissue. Treating such a patient with thyroid hormone is not sensible and appears to increase the risk of breast cancer. Study of radioiodine uptake in normals and women with fibrocystic breast disease FDB reveals that the FDB breasts were able to take in 12.5% of the iodine dosage compared to only 6.9% in normal breasts. This proves the existence of considerable iodine depletion in the breasts of women with FDB. There is considerable evidence for an increased risk of thyroid cancer as well as breast cancer in persons with iodine deficiency. Untreated iodine deficiency leads to goiter, thyroid nodules and eventually some of these nodules become malignant. The decreasing intake of iodine has resulted in an increase in thyroid nodules and increase in thyroid cancer. In 2001 there were 19,500 new cases of thyroid cancer in the U.S. with 14,900 of these cases occurring in women. Iodine has a role in promoting general well being as well as protecting against infections, degenerative diseases and cancer. Iodine promotes the normal killing of defective and abnormal cells (apoptosis). Thus, iodine helps the body’s surveillance system to detect and remove abnormal cells. Additionally, the presence of iodine triggers differentiation away from the more dangerous undifferentiated type of cell toward normal cells. The presence of adequate levels of iodine in the body (Japanese diet with lots of sea vegetables and fish) reduces reactive oxygen species (ROS)(.SPECIAL NOTE THIS ALSO IS EATEN IN THE MEDITEREANAN DIET AS WELL AS THE NORTHERN EUROPEANS, AFRICAN COAST LINES, MIDDLE EASTERN COASTAL AREAS AS WELL. IN NORTH AMERICA ( CANADA , USA , MEXICO ) WHERE COMMERCIAL FOODS ARE PROCESSED WITH THYROID DAMAGING FOODS, THE INCIDENCE OF THYROID CANCERS ARE HIGH AS A RESULT OF TOXIC POISONS BLENDED IN THE FOODS ) in the body which decreases the oxidative burden in the body This results in slowing of degeneration disease processes and decreasing the risk of cancer. Nearly every physician in the United States will reach for a prescription pad to order thyroid hormone when he sees a patient with goiter or symptoms of hypothyroidism. This can be exactly the wrong thing to do if the patient has deficient stores of iodine. Insist on obtaining a 24 hour urine collection for iodine to eliminate iodine lack as the cause for your symptoms (values below 50 ug/liter are abnormal). Thyroid hormone therapy in the presence of iodine deficiency increases the risk of breast cancer and probably thyroid cancer as well. Endocrinologist, Dr. Guy Abraham, formerly of the U.C.L.A. Department of Endocrinology, is convinced that everyone needs to be on iodine therapy until their iodine stores have been fully restored. After this time frame periodic intake of iodine will help insure that the many body functions requiring iodine run smoothly. A dosage of two tablets of Iodoral twice daily for three months followed by one Iodoral tablet daily for a year will restore iodine stores for most persons. At that point periodic taking of an Iodoral tablet daily one month out of 4 to 6 months etc. will be adequate to maintain iodine stores. Iodine stores can be easily monitored by taking 4 Iodoral tablets (50 mg iodine) and collecting a 24 hour urine sample for iodine content. If 80% of the ingested iodine is found in the urine collection the iodine stores are normal. Iodoral can be obtained from Optimox Corp. Torrance, Cal. To purchase a referral from a health care practitioner is needed. SPECIAL NOTE ; INCORPORATE SEAWEED IN THE DIET BY EITHER SUPPLEMENTATION OR DIRECTLY PURCHASING SEAWEED AT ANY ETHNIC MARKET OR HEALTH FOOD STORE THAT SELLS THIS, YOU CAN ALSO GET KELP TINCTURES AND USE THEM AS A PREVENTATIVE BY UTILIZING THEM AS NEEDED …SOME GOOD TINCTURES ARE LUGOLS ( HAS 7.5 MGS PER DROP) ATOMIDINE ( 600MCGS> THEN 1 MG SO YOU CAN USE MORE OF THIS THEN THE LUGOLS) OR JUST ANY KELP OR SEAWWEED TINCTURE WHICH IN ALL LIKELIHOOD HAVE ABOUT 300-600MCGS. ( MCGS = MICROGRAMS) IT TAKES 1000 MCGS TO MAKE 1 MILLIGRAM ( 1MG) Footnotes:

    1, Abraham, Guy F. et al Orthoiodosupplementaion: Iodine Sufficiency Of The Whole Body pg 1

    2, Hintze, G. et al treatment of Endemic goiter due to iodine deficiency with iodine,

    levothyroxine or both:results of a multicentre trial. European Journal of Clinical Investigation,

    19:527-534, 1989

    3, Eskin B et al Mammary Gland Dysplasia in Iodine Deficiency JAMA , 200:115-119. 1967

    4, Eskin B Iodine and Mammary Gland Cancer Adv. Exp. Med. Biol., 91:293-304, 1977

    5, Ghent, W. et al Iodine Replacement in Fibrocystic disease of the Breast Can. J. Surg. , 36:453-

    460, 1993

    6, Eskin B. et al Different Tissue Responses for Iodine and Iodidein Rat Thyroid and mammary

    Glands Biol. Trace Element Research 49:9-19, 1995

    7, Derry , D Breast Cancer and Iodine Trafford Publishing, Victoria B.C. , 92, 2001

    8, Finley JW., Bogardus, G.M., Breast Cancer and Thyroid Disease Quart. Review Surg. Obstet.

    Gyn. 17:139-147, 1960

    9, Smtyhe, P. , Thyroid Disease and Breast Cancer J. Endo. Int. , 16:396-401, 1993

    10, Ghandrakant, C. et al Breast Cancer Relationship to Thyroid Supplements for

    hypothyroidism JAMA, 238:1124, 1976

    11, Backwinkel, K., Jackson, A.S. Some Fearures of breast Cancer and Thyroid Deficiency

    Cancer17:1174-1176 , 1964

    12, Epstein, S.S., Sherman, D. Breast Cancer Prevention Program Macmillan , NY. 1998 pg 5

    13, Ibid



    Conditions Helped:

    Pain of any kind: Ankylosing Spondylitis, Arthritis, Back Problems, Lower, Back Problems, Neck, Diabetes, Leg Ulcers, Oteoporosis, Polymyalgia Rheumatica, Prostate Problems, Repetitive Strain (RSI) Carpal Tunnel etc, Rheumatoid Arthritis

    Inflammation of any kind including : Breast Engorgement,

    Cystitis joints or muscles, Fibrocystic Breast Disease, Inflammatory bowel diseases (Ulcerative Colitis, Crohn’s, IBS.), Lupus Lung & Chest Problems: Asbestosis, Miners and Farmers Lung, Bronchiectasis, Bronchial Asthma, Bronchitis, Coughs,

    Cystic Fibrosis , Emphysema, Pulmonary Tuberculosis, Eye Problems: Inflammation, Blocked veins etc Multiple Sclerosis & other Neurological problems: Damaged Nerves, Multiple Sclerosis Ear, Nose & Throat problems: Chronic ear infection , Catarrhal Rhinopharyngitis, Hayfever, Sore Throat, Swollen Glands, Laryngitis, Runny nose/Rhinitis, Sinusitis problems

    Trauma: Sports Injuries, prevention & Recovery, Traumatic swelling/

    Oedema/Edema, Post Operative & Traumatic Swelling, Post Operative Scars & Lesions Cardiovascular: Varicose Veins & Thrombophlebitis, Cardiovascular Disease,Arterial Disease, Angina, DVT, Blood Clots Other Conditions: Anti-ageing , Animal treatment The enzyme activity is measured in units and clinical studies are based on the ratio of 10 mg of Serrapeptase equaling 20,000 units of activity. When purchasing the product be sure that the ratio of mg to units is 10 mg for every 20,000 units, or 5 mg for 10,000 units and so on. The average dose, therefore, is 20 mg–or 40,000 units. Serrapeptase digests non-living tissue, blood clots, cysts, and arterial plaque and inflammation in all forms. The late German physician, Dr. Hans Nieper, used Serrapeptase to treat arterial blockage in his coronary patients. Serrapeptase protects against stroke and is reportedly more effective and quicker than EDTA Chelation treatments in removing arterial plaque. He also reports that Serrapeptase dissolves blood clots and causes varicose veins to shrink or diminish. A MEDICAL PRACTIONER told of a woman scheduled for hand amputation and a man scheduled for bypass surgery who both recovered quickly without surgery after treatment with Serrapeptase.




    STOMACH PANCREATIC INSUFFIECENCY ( NOT ENOUGH ENZYME BEING PRODUCED OR DUE TO AGING NOT FUNCTIONING AS IT SHOULD) INTESTINAL OBSTRUCTION ( EXCESS WASTE OR FOODS THAT INHIBIT INTESTINAL ENZYMES) USED IN DEBRIDEMENT ) OF ULCERATION (Surgical excision of dead, devitalized, or contaminated tissue and removal of foreign matter from a wound, EMPYEMAS(The presence of pus in a body cavity, especially the pleural cavity.)FISTULAS (An abnormal duct or passage resulting from injury, disease, or a congenital disorder that connects an abscess, cavity, or hollow organ to the body surface or to another hollow organ.) NECROTIZING WOUNDS (means damage and death of cells ) ABSCESSES (A localized collection of pus in part of the body, formed by tissue disintegration and surrounded by an inflamed area.) HEMATOMAS (A localized swelling filled with blood resulting from a break in a blood vessel.) DECUBITUS ULCERS ( BEDSORES) AN AUXILLARY AGENT FOR MENINGITUS (Inflammation of the meninges of the brain and the spinal cord, most often caused by a bacterial or viral infection and characterized by fever, vomiting, intense headache, and stiff neck)


    INTERCOSTAL NEURITIS (. Inflammation of a nerve or group of nerves, characterized by pain, loss of reflexes, and atrophy of the affected muscles, Located or occurring between the ribs) URTICARA (HIVES) POSTOPERATIVE PAROTITIS (Inflammation o the parotid glands, as in mumps.) BEDSORES, PLEURAL EFFUSION ( an exudation{ oozing forth} of fluid from the blood or lymph into a pleural cavity) INFECTED WOUNDS, SCARS, PANCREATITIS(is a rare disease in which the pancreas becomes inflamed,) TRENCH MOUTH(A progressive painful infection of the mouth and throat with ulceration, swelling and sloughing off of dead tissue from the mouth and throat due to the spread of infection from the gums.), EXZEMATOID DERMATITIS(is an inflamation of the skin. The disorder has many causes including contact with an irritating substance, allergic reaction, eczema, and immune disease


    DISEASES (The blocking of a blood vessel by a blood clot dislodged

    from its site of origin )PERIPHERAL ARTERIOSCLEROSIS (A chronic disease in which thickening, hardening, and loss of elasticity of the arterial walls result in impaired blood circulation. It develops with aging, and in hypertension, diabetes, hyperlipidemia, and other conditions. Normally, the arteries of the arms and legs widen (dilate) and narrow (constrict) in response to changes in the environment, such as a change in temperature Functional peripheral arterial disease usually occurs when the normal mechanisms that dilate and constrict these arteries are exaggerated.) PULMINARY INFARCTS ( lung blockages as a result of dead tissue, or a blockage of blood supply to the lung tissue resulting in dying tissue) PERIPHERAL VASCULAR DISEASE ( outer blood vessels in the heart area, having blockages, and restricting blood flow) MILK LEG (A painful swelling of the leg occurring in women after childbirth as a result of clotting and inflammation of the femoral veins )ISCHEMIC PURULENT LEG ULCERS (Containing, discharging, or causing the production of pus as a result of poor circulation, boils are an example , either dead tissue as a result of poor circulation or and a pus leaking out )


    SWELLING AFTER A SURGERY SPEEDS HEALING FROM INJURIES ( INFLAMMATION OR SWEELING), THIS INCLUDES SPRAINS, STRAINS, CONTUSIONS (An injury in which the skin is not broken; a bruise), FRACTURES, BLACK EYE, HEMATOMAS (A localized swelling filled with blood resulting from a break in a blood vessel) TENDONITIS, AND BURSITIS TREATS, ASSIST IN HEALING RHEUMATOID ARTHRITIS (A chronic disease marked by stiffness and inflammation of the joints, weakness, loss of mobility, and deformity) AND ACUTE GOUTY ARTHRITIS (arthritis associated with gout and caused by the deposition of urate crystals in the articular cartilage of joints ) TREATS SKIN DISORDERS, including ATOPIC DERMATITIS (Dermatitis characterized by intense itching, occurring in individuals predisposed to developing certain hypersensitivity reactions ) PUSTULAR ECZEMA (A small inflamed elevation of the skin that is filled with pus; a pimple ) EXZEMATOID DERMATITIS (is an inflamation of the skin. The disorder has many causes including contact with an irritating substance, allergic reaction, eczema, and immune disease ) ASSIST EFFECTIVELY IN THE TREATMENT OF RESPIRATORY AND THROAT INFECTIONS, INFLUENZA ( the flu) BRONCHITIS, TUBERCULOSIS ADENITIS (Inflammation of a lymph node or gland, An infectious disease of humans and animals caused by the tubercle bacillus and characterized by the formation of tubercles on the lungs and other tissues of the body, often developing long after the initial infection ) LUNG ABSCESS, INFECTED BRONCHOPLEURAL FISTULA ( AN INFECTION IN AN AREA WHERE THE (Communication between bronchus and pleural cavity occur ) BRONCHIAL ASTHMA, SINUSITIS, PERITONSILLAR ABSCESS (An abscess formed usually above and behind the tonsil, due to extension of infection beyond the tonsillar capsule. Also called QUINCY) PULMONARY DISEASE, PULMONARY EMPHYSEMA (a common disease of the lungs in which the air cells are distended and their partition walls ruptured by an abnormal pressure of the air contained in them ) UNRESOLVED PNEUMONIA -ATELECTASIS (An acute or chronic disease marked by inflammation of the lungs and caused by viruses, bacteria, or other microorganisms and sometimes by physical and chemical irritants. AND CAUSES COLLAPSING OF THE LUNS AS WELL) PULMONARY TUBERCULOSIS, TRAUMATIC HYPEREMIA (An increase in the quantity of blood flow to a body part; engorgement AS A RESULT OF AN INJURY) and VIRAL PNEUMONIA TREATING


    VENEREUM( STD, an inflammation of lymph nodes as a result of

    exposure to granulomalike lesions ) GONORRHEAL URETHRITIS,

    PROTEUS VULGARIUS OF THE URINARY TRACT(A bacterium found in putrefying materials and in abscesses; it includes strains that agglutinate in typhus serum and are therefore used in diagnosis of typhus ) EYE CARE, SUCH AS, GLAUCOMA, ACUTE IRIDCYCLITIS (Inflammation of the iris and the ciliary body ) THROMBOSIS OF CENTRAL RETINAL VEIN( a blood clot in the retinal area ) FOR DIABETES MANAGEMENT TO PREVENT CELLUTIS, INFECTED LEG ULCERS, AND CARBUNCLE (A painful localized bacterial infection of the skin and subcutaneous tissue that usually has several openings through which pus is discharged ) CANCER FIGHTER, AND PROBLEMS ASSOCIATED WITH CANCER SUCH AS..ASCITES (An abnormal accumulation of serous fluid in the abdominal cavity ) DUE TO CANCER OR CIRRHOSIS (A chronic disease of the liver characterized by the replacement of normal tissue with fibrous tissue and the loss of functional liver cells. It can result from alcohol abuse, nutritional deprivation, or infection especially by the hepatitis virus.) AND LYMPHOSARCOMA (A diffuse malignant lymphoma ) WITH INFECTION IT IS ONE OF THE 4 PROTEOLYTIC ENZYMES IN THE PANCREATIN

    Also when garlic is combined with cayenne pepper it to has an analgesic effect…tumeric with pineapple…papaya with pepper, even coffee before an activity wil reduce pain. Grapefruit with any kind of herbal pain kiler will extend the effects of the herbs in use. Certain oils like Olive and Wheat Germ oil also have pain reduction activity due to the Vitamin E and octacosanol and polyphenols content of these oils.


    Calgary Workshop 2 –Araya


    Benefits of Iodine–Benefits of GSE–Sixty Uses Of Baking Soda-Combating radiation poisoning tips-Cold Distilling Wine-Seed Milk-APPLE/ BEET/PEPPERMINT-Making Butter-Making Lugols Iodine-Making a Alkalizer-Using Essential Oils on food-Open questions


    Iodine is utilized by every hormone receptor in the body. The absence of iodine causes a hormonal dysfunction that can be seen with practically every hormone inside the body. Dr. Flechas has recently been able to show that patients with insulin resistant diabetes have a partial to full remission of their illness in the presence of taking iodine. Iodine deficiency is also felt to be the source of ovarian cysts. With iodine replacement therapy the cysts disappear and women have stopped having ovarian cysts.”-All cells in the body need iodine for proper functioning. All glands (thyroid, adrenal, etc.) especially need iodine for the production of hormones. Dr. Brownstein believes that iodine deficiency is a major cause of breast cancer and other diseases of the reproductive organs such as ovarian, uterus and prostrate cysts and cancers. Iodine levels in US soil have fallen 50 per cent over the past 50 years and soil in the US is deficient in iodine. The Great Lakes region has some of lowest soil iodine levels in the world and this results in high levels of cancers related to iodine deficiency. Dr. Brownstein has been quite successful in treating fibrocystic breast disease (cysts in the breast) with iodine/iodine supplementation. In one case a 37 year-old woman with severe fibrocystic breast disease was completely cured after supplementing with 50 mgs of iodine a day for two months. Women with large breasts need more iodine than women with smaller breasts. Other medical authorities agree that iodine deficiency can lead to fibrocystic breast disease and/or ovarian cysts Iodine can similarly reduce uterine fibroids and one of the first conventional medical treatments for severe fibroids was to paint the uterus with iodine. [4] Some other medical conditions associated with iodine deficiency are goiters, Graves’ Disease, Hashimoto’s Disease, fatigue and impaired immune system function. Iodine deficiency during pregnancy can lead to miscarriages and reduced IQ in surviving offspring. The World Health Organization says that iodine deficiency is the largest single cause of mental retardation. Iodine also detoxifies the body by removing mercury, fluorides, chlorides, and bromides.


    “If you think you may be deficient in Iodine, consider this; most of the US population has one or more mercury amalgam fillings in their mouths. A consequence of this is that minute amounts of the heavy metal mercury are continuously being released into the mouth and absorbed into the body. This toxication stimulates a natural detox reaction by the body. Several mechanisms are utilized to remove the mercury. In order for these detoxification mechanisms to work properly, numerous essential minerals are utilized. Iodine, Zinc, Sulfur, Selenium, and Silica stimulate the excretion of heavy metals including mercury. Iodine is at the top of the list when it comes to mercury removal. —“Unfortunately, the average persons daily intake of Iodine is not high enough to keep them mercury free even when not exposed to excessive levels. Add on the exposure of mercury from vaccinations, smoking, etc., and you have the potential for serious heavy metal toxicity. This toxicity can manifest itself in many ways causing problems that would not normally be attributed to high levels of mercury.

    “Iodine is essential for the health of the: Thyroid, Breast and Prostate.

    “Iodine chelates: · Mercury · Lead · Cadmium · Aluminum · Bromide

    “Iodine helps to improve: · Bowel irregularity · Brain fog · Renaud’s syndrome (numb finger tips) · Low energy · Sensitivity to cold · Skin complexion

    “In addition to mercury toxicity, you naturally have a major deficiency in the essential mineral Iodine if you are getting at or below the outdated RDA. Additionally, fluoride is an antagonistic element to Iodine, meaning it will impede the absorption of Iodine. Many of us are forced to drink fluoridated water and also brush our teeth with fluoride. Could an Iodine deficiency be related in some way to the current epidemic of hypothyroidism, breast, and prostate cancers? The protective function of Iodine in these tissues has not been described, but the fact that these tissues when healthy are replete with Iodine, and when diseased have little or no Iodine, leads one to think there is more than a casual link.”


    Out of 540 Gastro-Intestinal cases, 494 WITH FAVORABLE RESULTS. Out of 691 Urinary Disorders, 614 WITH FAVORABLE RESULTS. “Good results in several cases of GASTRO-INTESTINAL DISORDERS.” Report #1693.

    “STOMACH ULCER cases are all well. Full recovery. Quite a feat as those were old ones and medical men were quite helpless.” Report #1976.

    “Satisfactory in GASTRO-INTESTINAL DISTURBANCES.” Report #2089.

    “Another intensely valuable property is its undoubted active therapeutic effect in the control of PUTREFACTIVE AND FERMENTATIVE CONDITIONS OF THE GASTRO-INTESTINAL TRACT.” Report #117.

    “GASTRO-INTESTINAL CASES cured with nascent iodine.” Report #2258.

    “STOMACH TROUBLES responded liberally as well as URINARY DISORDERS.” Report #127.

    “GENITO-URINARY INFECTIONS – out of 320 cases, 84 CURED, 216 IMPROVED.” Hospital Report #1935.

    “Diseases of URINARY TRACT, I cured about 20 with very nice results.” Report #1934.

    “As a Urinary antiseptic in the presence of inflammation in the urinary tract, nascent iodine, I find SUPERIOR TO ANY OTHERS.” Report #1945.

    Out of 1029 cases decided, 978 WITH FAVORABLE RESULTS. Report #1559.

    “I have found a MEDICATION TO REDUCE BLOOD PRESSURE. A woman 80 years of age – BLOOD PRESSURE 210 – nascent iodine given in ten minim doses three times daily for five days. B.P. reduced to 160 – Five more days EFFECTED A REDUCTION TO 148.” Report #190.

    “Find it DOES NOT PRODUCE IODISM. Use it myself for HIGH BLOOD PRESSURE. Other iodine preparations give me iodism very quickly.” Report #1581.

    “Woman age 50 with a PRESSURE OF 285. Took it three times to make sure. Placed on 15 drops of nascent iodine three times a day for two weeks. The PRESSURE WENT DOWN TO 240, patient much improved. Man age 65 with a PRESSURE OF 180 – placed on nascent iodine. PRESSURE DOWN TO 150 – PATIENT DOING VERY WELL.” Report #1162.

    “Found it very reliable drug in controlling HIGH BLOOD PRESSURE. Report #115.

    “A woman complaining of violent headaches, dizziness, fatigue on slightest exertion. On taking the blood pressure, IMAGINE MY ALARM AT FINDING IT WAS 280. Today, only three weeks later, she was helping her husband in the field. Her husband is overjoyed and she herself is SINGING MY PRAISES TO THE NEIGHBORS. What did I give her? Ten drops of nascent iodine in half a glass of water 30 minutes before meals.” Report #1688.

    “Case of HYPERTENSION with considerable discomfort from dizziness and pounding in the head. These symptoms have improved. The BLOOD PRESSURE DROPPED TO 150 and this has been WITH NO GASTRIC DISTRESS.” Report #1742.


    Out of 583 cases decided, 558 WITH FAVORABLE RESULTS. Report #1559.

    “I use nascent iodine always as the REMEDY OF CHOICE where Iodine is Indicated in DEFICIENCY DISEASES. The action is prompt.” Report #1945.

    “This form of iodine is without question our MOST VALUABLE THERAPEUTIC AGENT for the prevention and treatment of GOITRE.” Report #117.

    “Had wonderful success with nascent iodine. GOOD RESULTS FOR GOITRE.” Report #1778.

    “Use nascent iodine regularly for FURNISHING IODINE TO THE SYSTEM. Report #1943.

    “Used nascent iodine when iodine is called for. IT IS CLEAN, NO STAIN, AND EFFECTIVE.” Report #2022.

    “EXCELLENT results IN GOITRE of young girls.” Report #2031.

    “All cases where iodine is indicated. WORKS WONDERS WITH CHILDREN.” Report #2106.


    “MALARIA FEVER, INTERMITTENT TYPE. Troubled with it years before. Gave nascent iodine. In three weeks NO TRACE OF MALARIA REMAINED. I GAVE ALL BLOOD TESTS. No return of the ailment. Report #1959.


    “Nascent iodine is an ASSET TO THE TROPICAL MEDICINE. Its virtues are unsurpassed in treating various TROPICAL FEVERS.” Report #1936.

    “Male patient, TERTIAN MALARIA PROVEN BY SLIDE. CONTRACTED MALARIA 18 YEARS AGO. He was treated in the American Hospital but suffered relapses. Since the time he took nascent iodine he is FREE FROM FEVER. TOOK THREE MORE SLIDES – ALL NEGATIVE. THE LAST TWO YEARS HE NEVER HAD FEVER FOR ONE DAY.” Report #1937.

    “Successfully tried several cases of MALARIA INFLUENZA AND OTHER FEVERS. Temperature becomes normal within twenty-four to forty-eight hours WITHOUT CAUSING ANY HARMFUL OR DEPRESSING EFFECTS ON THE HEART or reducing the vitality of the patient.” Report #1942.

    “DENGUE FEVER, BLACKWATER AND ALL TYPES OF MALARIA are brought under control within 48 hours. Fever in general disappears after the third day. The general weakness following all fevers disappears within a week. IN NO CASE GASTRO-INTESTINAL SYMPTOMS FOUND TO APPEAR AS IN THE CASE OF QUININE in fever.” Report #1967.

    “In fevers it is very fine and the improvements are soon noted. IT IS NON-TOXIC AND DOES NOT LEAVE ANY UNTOWARD AFTER EFFECTS to be feared.” Report #127.


    “A case of THIRD DAY CHILLS. Gave nascent iodine 4 weeks ago. Not had any more chills and feeling fine. So a GREAT DISCOVERY, I think.” Report #2154.

    “FOUND nascent iodine SUPERIOR TO QUININE, as it promptly checks chills and brings the fever under control within 24 to 48 hours and there is a complete absence of undesirable symptoms associated with the use of quinine. nascent iodine IS WELL TOLERATED BY THE SYSTEM.” Report #2159.

    “Used nascent iodine in OBSTINATE CASES OF MALARIA fever with splendid results.” Report #2178.

    “Results have been very gratifying in the treatment of MALARIA. TREATED 5 CASES. In each case temperature dropped to normalcy in a few hours and had NO RETURN OF CHILLS OR FEVER.” Report #2164.

    “Used nascent iodine in FOUR CASES OF MALARIA with splendid results. All symptoms subsided. Appetite greatly improved. BLOOD SMEARS NEGATIVE FOR MALARIA.” Report #2181.

    “Pleased at results obtained in treating MALARIA with nascent iodine. Your preparation WILL HAVE WIDE FIELD OF USE IN MALARIAL CONDITIONS.” Report #2221.

    “Used nascent iodine in a case of TERTIAN MALARIA, with splendid results. BLOOD NEGATIVE ON ALL FORMS IN FIVE DAYS.” Report #2230.


    “NEISSERIAN INFECTION; 58 cases under observation. 28 CASES SHOW NEGATIVE SMEARS, decrease in the amount of discharge, disappearing of erosions. 11 cases show no improvement as to the amount of cervical discharge although smears were negative. 16 cases left the hospital.” City Hospital Report #1645.

    “Tried nascent iodine over Venereal patients and found a REALLY RESPONSIVE PRODUCT. See no reason why every practitioner cannot get similar results.” Report #2134.

    “In CHRONIC GONORRHEA CASES OF BOTH SEXES improved immediately the vital resistance of the patient, alleviating at once the GENITO-URINARY symptomatically. Good benefits results in cases of SYPHILIS IN ITS 2ND AND 3RD STAGE.” Report #1655.

    “URETHRAL GONORRHEA, associated with STREPTOCOCCI INFECTION. Nascent iodine was given internally. Injections were given in Urethral tract. IN THREE WEEKS THE CASE WAS NEGATIVE to both gonorrhea and streptococcus.” Report #2166.

    “Found nascent iodine UNEXCELLED IN THE TREATMENT OF SYPHILIS. TREATED 50 CASES.” Report #2159.

    “Using nascent iodine IN PREFERENCE TO K. I. IN LUES.” Report #1594.


    THROAT INFECTIONS – Out of 1155 cases decided, 1122 WITH FAVORABLE RESULTS. Report #1559.

    “Five to ten drops of nascent iodine put into one ounce of water makes an excellent collyrium (eye lotion). I have used it on my servant girl in a SEVERE INFLAMMATION OF BOTH EYES – of uncertain origin and diagnosis – that had resisted several kinds of treatment during three months. Above mentioned collyrium put into her eyes two drops two or three times a day. It had COMPLETELY CLEARED UP IN ONE WEEK.” Report #2180.

    “During the past five years I have been trying different drugs to shorten the purulency of a SUPPERATING MIDDLE EAR. Recently I have been trying nascent iodine in a preparation which produces NASCENT IODINE. I used 1/2% in oil. [A special preparation of nascent iodine in oil, made according to the specifications of a leading Nose, Ear and Throat Specialist, is available on request.] The strength not only did not give pain but was distinctly beneficial. A series of cases was subjected to it with cures in a week to two weeks. Tried it with MAXILLARY ANTRITIS cases with striking benefit. Whatever specific action nascent iodine has, antiseptic or cytefacient is not known, but there is a cessation of the discharge and the local protection is increased.” EAR, NOSE AND THROAT CLINIC. Report #1741.

    “SINUS INFECTION. Nothing seemed to help except nascent iodine, and this is an UNUSUALLY DIFFICULT CASE where everything failed.” Report #1953.

    “Fine remedy for SINUS TROUBLE. I use a lot of it.” Report #1635.

    “I used it several times on a CHRONIC SINUS where tonsil had been removed. The sinus is apparently well. I have cured two cases of CHRONIC OTORRHEA with diluted solution.” Report #2259.


    “PHARYNGITIS AND TONSILLITIS cases under observation, fifty-two. In FORTY-SEVEN CASES IMPROVEMENT OCCURRED within three to five days with subsidence of pain, fever and congestion. The solution was employed in swabbing the throat thoroughly.” CITY HOSPITAL. Report #1687.

    “Found satisfactory in the treatment of SINUS INFECTION, ACUTE AND CHRONIC.” Report #2052.


    “HAD CHRONIC BRONCHITIS FOR OVER SEVEN YEARS. Tried many doctors and remedies, with no success. Took three bottles of nascent iodine. I am now well. NO SIGNS OF OLD TROUBLE SINCE. Recommend it to all my patients. WORTH ALL THAT IS CLAIMED FOR IT.” Report #1947.


    “Had MOST EXCELLENT RESULTS in all the treatment of ASTHMA AND BRONCHITIS.” Report #2254.

    “Had MOST EXCELLENT RESULTS in all the treatment of ASTHMA AND BRONCHITIS.” Report #2254.

    “CHRONIC BRONCHITIS case responded nicely after taking nascent iodine.” Report #2259.

    “Very good success in relieving a case of BRONCHIAL ASTHMA.” Report #289.

    “Good results in CHRONIC BRONCHITIS.” Report #1565.

    “Fine for ACUTE AND CHRONIC BRONCHITIS.” Report #2064.

    “Found satisfactory in the treatment of BRONCHITIS AND ASTHMA.” Report #2077.

    “Nascent iodine three times daily stopped PERSISTENT COUGH OF LONG STANDING.” Report #2165.


    “We have used nascent iodine and FOUND IT SATISFACTORY IN EVERY WAY.” HOSPITAL FOR JOINT DISEASES. Report #124.

    “ARTHRITIS: out of 265 cases, 53 CURED, 185 IMPROVED.” SAILORS HOSPITAL. Report #1935.

    “Tried on ARTHRITIS patient who had right knee and wrist swollen, and very painful on least movement. In three days she could move the knee and wrist a lot better and less pain.” Report #2157.

    “I have found nascent iodine UNEXCELLED IN THE TREATMENT OF RHEUMATISM, TREATED 50 CASES.” Report #2159.

    “Nascent iodine has helped me personally – the OLD RHEUMATIC CONDITION gave way to your ‘Water Soluble’ iodine compound.” Report #130.

    “Got EXCELLENT RESULTS IN A CASE OF ARTHRITIS of the knee.” Report #197.

    “Found satisfactory in the treatment of CHRONIC RHEUMATISM.” Report #2086.


    Out of 515 cases decided, 483 WITH FAVORABLE RESULTS. Report #1559.

    “Severe case of IVY POISONING. Found it to be ALMOST A SPECIFIC.” Report #226.

    “CASE (1) “Had been in a local hospital for seven months with STREPTOCOCCUS INFECTION. Draining pus from seven incisions. Prescribed nascent iodine. In two months most of the wounds healed. (2) Severe INFECTION OF TOE NAIL, SEPTIC POISONING SET IN. Gave nascent iodine internally. In four days the infection was cleared up. (3) LEUCORRHEA DISCHARGE WHICH HAD RESISTED EVERY FORM OF MEDICINE. Prescribed nascent iodine douches. In two weeks discharge stopped and the female organs resumed their natural position.” Report #206.

    “I have prescribed nascent iodine in many hundreds of cases as a PREVENTIVE AND PROPHYLACTIC in periods of epidemics with marked benefits. As an abortive in infections it has marked and rapid inhibitory action, proving beyond the least doubt that IT HAS DECIDED INTERNAL ANTISEPTIC OR GERMICIDAL ACTION.” Report #1945.

    “GIVING IT FIRST PLACE, NOT ONLY IN FIRST AID but think of nothing else when I treat infections. IT IS REALLY WONDERFUL.” Report #193.



    Health Benefits of Iodine


    Cells–Iodine deficiency is associated with impaired Growth.

    Ears/Hearing—Hearing impairment (Deafness) may occur as a result of Iodine deficiency.

    Immune System—Iodine deficiency may increase the risk of some forms of Cancer and Iodine may help to prevent some types of Cancer:

    ùBreast Cancer has been linked to Iodine deficiency.

    ùEndometrial Cancer has been linked to Iodine deficiency.

    ùOvarian Cancer has been linked to Iodine deficiency.

    – Thyroid Cancer – Uterus Cancer

    Iodine (consumed orally, applied topically or used as a mouth gargle) may kill many types of Detrimental Bacteria (a 1:20,000 solution of Iodine kills most Bacteria within one minute of contact).

    Iodine may kill several forms of Detrimental Fungi.

    Metabolism—Iodine may enhance the conversion of Adipose Tissue (body fat) into Energy (when the Thyroid Gland is under-functioning).

    Iodine may increase the Basal Metabolic Rate (BMR) (by stimulating the production of Thyroid Hormones).

    Iodine is involved in the production of Energy (due to its pro-oxidant properties).

    Goiter may occur as a result of Iodine deficiency.

    Hypothyroidism (i.e. under-active Thyroid) may occur as a result of Iodine deficiency and persons afflicted with Hypothyroidism may benefit from doses of supplemental Iodine in the vicinity of 1 mg per day:

    Caution: Excess Iodine may CAUSE Hypothyroidism.

    Iodine may cause weight loss where Obesity is caused by Hypothyroidism.

    Iodine is intricately involved with the Thyroid gland (20% of the body’s Iodine concentrates in the Thyroid Gland).

    Nervous System–Iodine deficiency (prior to and immediately after birth) may be an underlying cause of Amyotrophic Lateral Sclerosis (ALS) – this may occur from Iodine deficiency negatively affecting the development of the dopaminergic system that leads to an increased risk of ALS during later life). references

    ùùùIodine deficiency in mothers during Pregnancy may result in Attention Deficit/Hyperactivity Disorder (ADHD) in offspring.

    ùùùIodine deficiency has been associated with impaired Intelligence.

    ùùIodine deficiency may lead to impaired Learning ability.

    Iodine deficiency (prior to and immediately after birth) may be an underlying cause of Multiple Sclerosis (MS) – this occurs from Iodine deficiency negatively affecting the development of the dopaminergic system that leads to an increased risk of Multiple Sclerosis during later life). references

    Iodine deficiency (prior to and immediately after birth) may be an underlying cause of Parkinson’s Disease – this occurs from Iodine deficiency negatively affecting the development of the dopaminergic system that leads to an increased risk of Parkinson’s Disease during later life). references


    Oral Health–Iodine may improve the health of the Teeth.

    Respiratory System–Iodine (especially 1 ml of the Povidone Iodine form diluted in 20 ml of Water and used as a gargle in the Mouth every three to four hours) may alleviate many cases of Pharyngitis (sore Throat) where the underlying cause of Pharyngitis is a Virus.

    Sexual System-Fibrocystic Breast Disease may occur as a result of Iodine deficiency and supplemental Iodine may reverse Fibrocystic Breast Disease where the underlying cause of Fibrocystic Breast Disease is Iodine deficiency. references

    Iodine (especially the Potassium Iodide form) may reverse some cases of Ovarian Cysts (according to some doctors). references

    Iodine deficiency during Pregnancy may result in lowered Intelligence and increased risk of Attention Deficit/Hyperactivity Disorder (ADHD) in offspring. references

    Skin/Hair/Nails-Iodine may alleviate Dry Hair (where Dry Hair is due to an under-active Thyroid (Hypothyroidism)).

    Iodine may improve the health of the Nails. Dry Skin may occur as a symptom of Iodine deficiency.

    Iodine (tincture applied topically) may alleviate Tinea.






    Antibiotic/antiseptic, natural
    Athlete’s foot
    Canker sores
    Chronic fatigue syndrome
    Cold Sores
    Diaper rash

    Ear infections
    Food poisoning
    Fungus Infections
    Periodontal disease
    Sore throats
    Urinary tract infections
    used in treating secondary infections for aids and hiv sufferers
    Wash for veges and fruits
    foods of all sorts as well can be cleaned with it












    Sixty Uses Of Baking Soda

    Bicarbonate of soda or baking soda has many different uses in the household. Although much more expensive products have been developed over the years to do the same jobs, baking soda can work for you just as well, if not better. Use it in the following ways:

    1. To make your own baking powder, stir and sift together 2 parts of Cream of Tartar to 1 part baking soda and 1 part cornstarch.

    2. Be sure to keep an extra box of baking soda by your stove in case of grease or electrical fire. Scatter the powder by the handful to safely put it out.

    3. Keep a container of baking soda in your garage as well as in your car to put out a fire. It won’t damage anything it touches.

    4. Baking soda will also put out fires in clothing, fuel, wood, upholstery and rugs.

    5. Clean vegetables and fruit with baking soda. Sprinkle in water, soak and rise the produce.

    6. Wash garbage cans with baking soda.

    7. Soak and wash diapers with baking soda.

    8. Oil and grease – stained clothing washes out better with soda added to the washing water.

    9. Clean your fridge and freezer with dry soda sprinkled on a damp cloth. rinse with clear water.

    10. Deodorize your fridge and freezer by putting in an open container of baking soda to absorb odors. Stir and turn over the soda from time to time. Replace every 2 months.

    11. Soda absorbs kitty litter odors. Cover the bottom of the kitty box with 1 part soda; then add a layer of 3 parts kitty litter on top.

    12. Always add 1/2 cup soda to your washing machine load.

    13. Clean combs and brushes in a soda solution.

    14. Wash food and drink containers with soda and water.

    15. Wash marble-topped furniture with a solution of 3 tablespoons of soda in 1 quart of warm water. Let stand awhile, then rinse.

    16. Clean formica counter tops with baking soda on a damp sponge.

    17. Wash out thermos bottles and cooling containers with soda and water to get rid of stale smells.

    18. To remove stubborn stains from marble, formica or plastic surfaces, scour with a paste of soda and water.

    19. Wash glass or stainless steel coffee pots (but not aluminum) in a soda solution ( 3 tbsp. soda to 1 quart water).

    20. Run you coffee maker through its cycle with a soda solution. Rinse.

    21. Give baby bottles a good cleaning with soda and hot water.

    22. Sprinkle soda on barbecue grills, let soak, then rinse off.

    23. Sprinkle soda on greasy garage floor. Let stand, scrub and rinse.

    24. Polish silverware with dry soda on a damp cloth. Rub, rinse and dry.

    25. For silver pieces without raised patterns or cemented-on handles: place the silver on aluminum foil in an enamel pot. Add boiling water and 4 tbsp. baking soda. Let stand, rinse and dry.

    26. Reduce odor build-up in your dishwasher by sprinkling some soda on the bottom.

    27. Run your dishwasher through its cycle with soda in it instead of soap to give it a good cleaning.

    28. To remove burned-on food from a pan: let the pan soak in soda and water for 10 minutes before washing. Or scrub the pot with dry soda and a moist scouring pad.

    29. For a badly-burned pan with a thick layer of burned-on food: pour a thick layer of soda directly onto the bottom of the pan, then sprinkle on just enough water so as to moisten the soda. Leave the pot overnight, then scrub it clean next day.

    30. Rub stainless steel and chrome with a moist cloth and dry baking soda to shine it up. Rinse and dry. On stainless steel, scrub in the direction of the grain.

    31. Clean plastic, porcelain and glass with dry soda on a damp cloth. Rinse and dry.

    32. Remove that bad smell from ashtrays with soda and water.

    33. Sprinkle a bit of dry soda in your ashtrays to prevent smoldering and reduce odor.

    34. Clean your bathroom with dry soda on a moist sponge – sink, tub, tiles, shower stall, etc.

    35. Keep your drains clean and free-flowing by putting 4 tablespoons of soda in them each week. Flush the soda down with hot water.

    36. Soak your shower curtains in water and soda to clean them.

    37. To remove strong odors from your hands, wet your hands and rub them hard with soda, then rinse.

    38. Sprinkle baking soda on your wet toothbrush and brush your teeth and dentures with it.

    39. Sprinkle soda in tennis shoes, socks, boots and slippers to eliminate odor.

    40. Add 1/2 cups or more of baking soda to your bath water to soften your skin.

    41. Putting 2 tbsp. of baking soda in your baby’s bath water will help relieve diaper rash irritations.

    42. Apply soda directly to insect bites, rashes and poison ivy to relieve discomfort. Make a paste with water.

    43. Take a soda bath to relieve general skin irritations such as measles and chicken pox.

    44. Take 1/2 teaspoon of baking soda in 1/2 glass of water to relieve acid indigestion or heartburn.

    45. Gargle with 1/2 tsp. baking soda in 1/2 glass of water. Freshens and cleans your mouth.

    46. Used as a mouthwash, baking soda will also relieve canker sore pain.

    47. To relieve sunburn: use a paste of baking soda and water.

    48. Bug bites: use a poultice of baking soda and vinegar.

    49. Bee sting: use a poultice of baking soda and water.

    50. Windburns: moisten some baking soda and apply directly.

    51. Making Play Clay with baking soda: combine 1 1/4 cups water, 2 cups soda, 1 cup cornstarch.

    52. Use soda as an underarm deodorant.

    53. If your baby spits up on his shirt after feeding, moisten a cloth, dip it in baking soda and dab at the dribbled shirt. The odor will go away.

    54. When scalding a chicken, add 1 tsp. of soda to the boiling water. The feathers will come off easier and flesh will be clean and white.

    55. Repel rain from windshield. Put gobs of baking soda on a dampened cloth and wipe windows inside and out.

    56. Add to water to soak dried beans to make them more digestible.

    57. Add to water to remove the “gamey” taste from wild game.

    58. Use to sweeten sour dishcloths.

    59. Use dry with a small brush to rub canvas handbags clean.

    60. Use to remove melted plastic bread wrapper from toaster. Dampen cloth and make a mild abrasive with baking soda.

    Author: Harry Godwin -Date: 1/15/1999

    ` The Benefits of Baking Soda
    Health needs
    * Baking soda as a deodorant: Mix a cup of baking soda and 2 T. of cornstarch (to keep baking soda from clumping) and put it in a plastic container with a short-handled blush brush. Then after your shower you just brush on your deodorant. Since you’re still a little moist, it doesn’t have a problem sticking.

    * Make a cream deodorant by mixing 2 tablespoons baking soda, 2 tablespoons of petroleum jelly and 2 tablespoons talcum or baby powder. Heat in a double boiler or over very low heat, stirring constantly until it becomes smooth and creamy. Store in a container with tight lid. Another idea about using it as a deodorant: mix equal parts baking soda and cornstarch, then add water until it can be poured into a mold. After it dries you’ll have a ball of deodorant that you can moisten and apply. Be careful though, because baking soda IS caustic, and if you apply it to raw or tender skin (i.e. after shaving your armpits) it will burn.

    * Toothpaste – its a mildly abrasive tooth cleaner and mouthwash in one. (‘Dentist approved’) Add it to your tooth paste so it won’t taste too bad. Put the toothpaste on brush then simply sprinkle on top.

    * Use gently as an ex foliating facial scrub. Add a little baking soda to your facial cleanser instead of using facial scrubs. The little ‘grains’ are round and tiny, so are very gentle. Mix with oatmeal in your blender and it makes a marvelous facial scrub.

    * Soothe bee stings, and other insect bites by spreading a paste of baking soda and vinegar on it

    * Use in bath water to relieve irritated skin. (Good for baby, too)

    * Anti-acid, mix 1/2 teaspoon in about 4 ounces of water, and drink all at one time. It will cause you to ‘burp’, as it neutralizes stomach acid the same way it does other acids.

    * Put sunburned kids (or yourself) in a cool (not cold) baking soda bath for half an hour. This also works well for chicken pox and mosquito bites.

    * Use it to relieve the itch from poison ivy by making a paste with water and spreading it on the affected area and letting it dry. This also promotes healing by drawing out the poison.

    * In your hand, mix hair shampoo with a small amount of baking soda. Shampooing with this mixture easily removes old and heavy hair spray/spritz, etc., residue. If you mix baking soda and hair conditioner in your hand and only condition the ends of your hair it will give your hair more volume, body, and health.

    * From another reader: When my son was a baby he got heat rash on his little face – my doctor told me to sprinkle baking soda on his sheets because it would keep him from lying in his drool – worked!!
    From the same reader: The doctor also told me it was better than baby powder to use on baby’s – keeps them drier and cuts out any sour smells from burps

    * It’s said that if you put a small amount of baking soda in a 8 oz. glass of water and drink it, it will clean out your kidneys. (Note: Be aware that if your diet is salt restricted, you should not use baking soda for any internal reason, other than normal cooking.)

    * Mix a teaspoon of baking soda and a teaspoon of epsom salt in a glass of water to alkalinize your entire body and clean blood stream.

    * (check with your Optometrist first) For daily wear contacts that have protein buildup that enzyme cleaners don’t take care of, make a wet paste of baking soda and saline solution. Clean lenses in your hand with this paste, then follow your regular lens care routine. The mild abrasive will remove the deposits without harming the lenses, and they will feel like new.

    * From another reader: My two year old ran through a huge Fire Ant nest, ants covered her feet. Both feet turned bright red, I grabbed a bowl of water and box of soda, we soaked her feet in it for a while, you couldn’t tell she had ever been stung.

    * Apply baking soda and water paste to jellyfish or sea nettle stings to remove the burn.

    * Use Baking Soda if your hair is oily and you don’t have time to wash it. Sprinkle a little on your hair, comb it through and do a quick blow-dry and it works perfectly! It is great if you are in a hurry.

    * If your hair turns green from chlorine in swimming pools, just shampoo as usual but add 1/4 cup baking soda to your shampoo.

    * To relieve an upset stomach put a pinch of baking soda and a pinch of salt into a cup of mint tea. It’s not the best tasting thing in the world but it will ease and relieve an upset stomach.

    * It works great to defeat feminine odor problems. Just sprinkle a bit on a panty liner and wear as usual.

    * From another reader: I learned this from a make-up artist when I suffered from bad acne. For boils and large pimples make a paste out of baking soda and water. Pack it on the infected spot and it works to draw the infection.

    * for minor burns (1st degree burns) from ironing or from your oven while baking. Take baking soda and water make a thick paste and apply to the burn; leave on until it dries. It takes the pain away.

    * Another excellent use for baking soda is for mouth ulcers and cold sores. Simply mix a teaspoon of baking soda with 100mls of water and use as a gargle. For cold sores use the same solution however dab directly onto the cold sore using a cotton bud. Do this at least twice a day.

    * Sprinkle a small amount of Baking Soda onto palm, add a little water, and wash face. Leaves the skin feeling as though you had used a moisturizer. Test the difference by only washing one side of face, rinse, towel dry… then check the difference in skin softness.

    * From another reader: I’ve always had a really hard time getting a close shave. I’ve found that using a bit of baking soda mixed with water and scrubbing my face immediately before shaving helps remove oil from whiskers, making it easier for the razor to ‘grab’ them. It also works well to leave the soda on the face and apply shaving cream on top (although if you take your time shaving, it may start to sting a little before you finish).

    * Use baking soda to remove splinters. Make a paste of baking soda and water, and place the paste on a Band-Aid. Apply the Band-Aid to the affected area and leave for about 24 h. When you remove the Band-Aid, the splinter will be sticking out above the skin and can be pulled out easily. From another reader: I once got a shard of glass in my toe that was so deeply embedded that I couldn’t even see it. It took three days and three changes of the baking soda Band-Aid, but it came out. I was amazed to see that the shard was about 1 cm long!

    * If you have very oily skin. Mix Noxzema and a little Baking Soda. Mix it together so that it is evenly distributed and place it on your face. Let it dry and it makes your skin feel fabulous–while on your face and after you wash it off. It takes out the oil and makes your skin look wonderful!

    * The paste made from baking soda and a little water also works nicely applied to problem areas such as rosacea and viral or herpes-related pus modules (but do not scrub; the damaged skin is too sensitive for even baking soda’s gentle abrasion); it helps dry out the pus much better than any expensive medication and feels gentler.

    * Baking soda paste, when used as a scrub, also seems to help nail fungus for sweeter feet. From another reader: I had this problem and was told to soak my feet in a solution of Clorox and water. I found out baking soda works better anyway; I skip the Clorox altogether and my feet feel much better for it.




    Combatting radiation poisoning tips:
    Chelating (detoxifying) excess ionizing radiation & destructive radioactivity from your body and treating radiation burns naturally

    by Ulla, designer of Healing Cancer Naturally © 2006 & 2007
    Copyright Notice

    If you have submitted your body to ionizing radiation either for medical diagnostic purposes (fluoroscopy/mammography/other medical x-ray exams) or in the course of radiotherapy treatment, or if you are otherwise concerned by excessive radiation exposure, overload or poisoning (such as living near a nuclear reactor facility, working with diagnostic radiological equipment/in the nuclear processing industries/uranium mining/uranium or plutonium processing), or if you have been exposed to radioactive particles or higher ionizing radiation doses stemming from other sources such as depleted uranium (DU), testing of atomic weapons, frequent flights in higher altitudes etc., here are a number of tips and suggested remedies how to naturally help your body excrete damaging radioactive elements (e.g. strontium and radioactive iodine) or detoxify (or scavenge) their noxious byproducts such as free radicals as well as deal with radiation burns by using dietary, nutritional, herbal and other naturopathic approaches and modalities. Note: Healing Cancer Naturally does not endorse conventional cancer and tumor treatment by radiation therapy (radiotherapy/X-rays).

    In addition to the tips provided on this page, sells what looks like a well-researched ebook manual “How to Help Heal Your Body of Radiation Damage and Detox Away Ingested Radioactive Dusts” for $12. You can even download it for free. As with all such generous altruistic ventures, you are encouraged to support the author. So if you are interested in reading this guide and comfortably able to, I would suggest paying for this book rather than just taking it.

    Macrobiotic diet against radiation sickness

    Barbara Brennan writes in her classic Light Emerging, “If you are having any kind of radiation treatments, consider going macrobiotic. According to Michio and Aveline Kushi, macrobiotics is very effective in curing radiation sickness. In his book Macrobiotic Diet, Michio Kushi states: ‘At the time of the atomic bombing of Nagasaki in 1945, Tatsuichiro Akizuki, M.D., was director of the Department of Internal Medicine at St. Francis Hospital in Nagasaki. Most patients in the hospital, located one mile from the center of the blast, survived the initial effects of the bomb, but soon after came down with symptoms of radiation sickness from the radioactivity that had been released. Dr. Akizuki fed his staff and patients a strict macrobiotic diet of brown rice, miso* and tamari soy sauce soup, wakame and other sea vegetables , Hokkaido pumpkin, and sea salt and prohibited the consumption of sugar and sweets. As a result, he saved everyone in his hospital, while many other survivors in the city perished from radiation sickness.’”

    Compare On Macrobiotics, Seaweed for important hints re purchasing quality seaweed and Modifilan.

    Additional note by Healing Cancer Naturally: If you follow Dr. Johanna Budwig’s healing diet & protocol (which reportedly has also helped heal heavily irradiated (and “chemotherapied”) cancer patients formerly considered terminal and written off as beyond hope, see Budwig Testimonials), I would advise integrating the above-listed food items featuring prominently in the macrobiotic diet, such as seaweed, organic brown rice, miso soup etc. while leaving out or strongly curtailing honey and sweet fruit which are not permitted or heavily restricted in macrobiotics. Make sure to use truly organically grown foods: whole-grain rice is particularly laden with pesticide and similar toxic residues.

    Baking soda (sodium bicarbonate) baths (testimonial)

    “If you were near Chernobyl or if you had an X-rays or radiation treatments for cancer, my radionics practitioner said that you can soak your body in baking soda baths to help pull out the radiation from your body. If you look all over the web, there is talk about patients who have had mouth cancer who were given radiation treatments to get rid of the cancer, and then told to gargle with baking soda mixed in water.”

    Tip: If you look for online sellers of baking soda, you might pay a fraction for it as compared to buying in a store or pharmacy as long as you buy larger amounts (which you will need if you plan on bathing regularly). A friend bought it very cheaply at Ebay but there are bound to be similar venues where online merchants offer inexpensive baking soda.

    Baking soda (sodium bicarbonate) rinses

    “The most effective measure to treat RT-induced mucositis in patients with head and neck cancer is frequent oral rinsing with a sodium bicarbonate rinse, to reduce the amount of oral microbial flora.” (Oncol Nurs Forum. 2002 Aug;29[7]:1063-80. A research review of the current treatments for radiation-induced oral mucositis in patients with head and neck cancer. Shih A, Miaskowski C, Dodd MJ, Stotts NA, MacPhail)

    Baking soda (sodium bicarbonate) plus sea salt baths

    Similarly to the above, Barbara Brennan recommends in her classic Light Emerging to take 20-minute baking soda cum sea salt baths (mixing half a pound of salt and half a pound of baking soda) to drain the body of DOR (deadly orgone energy as described by Dr. Wilhelm Reich) etc. Since such baths are “energy draining”, she advises to be careful when getting up from them (circulation) and lie naked in the sun afterwards to recharge one’s battery. I would add the salt when the bathtub is somewhat filled already to avoid possible damage to any metal parts.

    Compare Sodium Bicarbonate Cancer Treatment: Treating Carcinomas & Destroying Tumors with Baking Soda: Is Cancer “Just a Fungus”?

    Epsom salt

    Epsom salts are a cheap white powder made of crystals of hydrated magnesium sulfate (chemical formula MgSO4 7H2O) which is used as a purgative etc. Any pharmacy or drug store should carry it. Use in baths. Epsom salts baths were part of this “terminal” colon cancer victor’s protocol.

    Cysteine hydrochloride

    Dr. Donsbach writes: “An amino acid, cysteine protects against the damage of radiation by terminating the free radicals produced by ionizing radiation.” Cysteine, together with methionine, cystine, and their derivatives, is numbered among the “sulphurated amino acids” due to the fact that these amino acids contain sulfur in addition to carbon, hydrogen, nitrogen and oxygen. Sulfurated amino acids are amply present in Dr. Johanna Budwig’s healing diet & protocol. (Note for cancer patients on Dr. Budwig’s Protocol: conceivably, taking isolated cysteine hydrochloride [versus taking it in its natural complex with other nutrients as occurring in organic foods] may not be compatible with the Budwig Diet which insists on shunning most man-made supplements.)

    Calendula officinalis: topical treatment of radiation burn scars
    For skin irritations and severe burns

    I have read that dried calendula flowers available from herbal and health stores or similar outlets as well as from the Internet make an excellent “tea” (to be applied topically) for severe burns and many skin outbreaks (get organic quality calendula if possible). While Weleda makes a Calendula Baby Cream, made with sweet almond oil, lanolin, beeswax, biodynamic calendula officinalis flower extract, perfume from natural essential oils and other ingredients, this may be less effective than this much less expensive herbal calendula tea:
    Pour a cup of boiling water onto 1-2 teaspoonsful of the florets and leave to infuse for 10-15 minutes (other sources may state different infusion practices and times). Use externally as a lotion or ointment (also recommended for cuts, bruises, diaper rash, sore nipples, other burns & scalds). Let dry after application. Completely safe and apparently non-staining. Can also be taken as tea.
    [Liquid Calendula for sale apparently is preserved with alcohol.]

    Echinacea for radiation burns (testimonial)

    “A friend of mine with stage 4 cancer used echinacea (probably standard dosage) which had been quietly suggested by her radiologist – and after whole body maximum lifetime dose radiation, never developed the radiation burns which seem to be so common. No lobster look. Might be worth looking into.”

    Aloe vera plant gel for radiation burns

    Reportedly, in 1959 the FDA “concluded from studies conducted by the Atomic Energy Commission at the radiation burn center at Los Alamos Laboratories in New Mexico that aloe gel did have a healing effect on skin tissue”. Suggestion: Use the fresh gel found inside the leaves – for instance cut the leaf lenghtwise and apply it on the burn with the gel side facing the skin. Compare Aloe Vera – the medicine plant.

    Epi-soothe cream for burns etc. (testimonial)

    “I’ve been using Epi-soothe cream and it works wonderfully for rashes, burns, open sores etc.!” See .

    Kombucha tea (testimonial)

    “I took kombucha all the way through my radiation (right over the stomach) and my doctor told me I was the only patient he’d had that never had nausea after being radiated in that area; it’s wonderful for your stomach and intestines. It’s much more potent and MUCH cheaper if you make it yourself. You just need a culture to start with. I make about 2 gallons at a time. It comes out to about 10 cents per bottle compared to $2-$3 in the stores.”

    Kombucha is a fermented or brewed beverage which is cultured for a number of days. Combined with tea, it contains active enzymes, probiotics (lactobacillus bacterium), amino acids, antioxidants, polyphenols and saccharomyces boulardi. Apparently very powerful with constipation (such as drinking half a glass 15 minutes before breakfast, with dosis increased as you get used to it.

    Two kombucha brewing tips

    Use green tea in your kombucha brew:
    Apparently green tea contains tumor growth inhibiting factors (a polyphenol named EGCG) as well as other polyphenols (such as flavonoids) reputed to lower cholesterol, counteract free radicals, exhibit natural antibiotic characteristics or prevent blood clotting. Other ingredients include vitamin C, carotene, fluoride, zinc, selenium, manganese, potassium, niacin & folic acid.

    Minimize or eradicate sugar:
    The consumption of processed or refined sugar has been shown to be a risk factor in a number of health complaints including cancer. “Sugar is required in Kombucha to provide food for the yeast resident in the culture. Research and experimentation has shown that the best type of sugar to use is ordinary granulated white sugar, i.e. sucrose. During fermentation the sucrose is broken down to its constituent parts, the simple sugars – glucose and fructose. Glucose is responsible for the formation of most of the organic acids with the exception of acetic acid, which derives from fructose. Glucose, which constitutes about 70% of sucrose, ferments far quicker than fructose and it is the latter which provides the residual sweetness in Kombucha.
    If you prefer less sweetness in your Kombucha you can either a) extend the fermentation period by a few days, thus further acidifying the brew, or b) replace some of the sucrose with glucose (dextrose monohydrate), often found in home brewing shops described as brewing sugar. A 50/50 mix is a good start and will produce a beverage high in organic acids with minimal sweetness in a short time, 6 to 8 days. You will probably find the perfect mix by trial and error.”

    So it seems to make sure there is no processed sugar left in your kombucha, it would be advisable to let it ferment as long as possible or reasonable to make sure all the sugar has been consumed by the yeasts.

    Above Kombucha tips have been adapted or copied verbatim from where you’ll find detailed preparation instructions and other kombucha information.

    Dr. Johanna Budwig’s health diet & protocol
    & side effects from radiation treatments

    Dr. Budwig expressly forbade cancer patients who followed her diet to treat their cancer, to concurrently use radiation and/or other cytostatic treatments (chemotherapy) arguing that any cytostatic treatments directly counteracted the “cytodynamic” effect of her diet, i.e. negated the effectiveness of the protocol (compare Budwig diet: what to avoid). Interestingly, Healing Cancer Naturally has come accross two reports where cancer patients did combine the Budwig Protocol with radiation treatments. Both reported that they did not have any side effects (or almost so) that the other patients were experiencing such as infections, pain, urination problems, etc. They attributed this to the Budwig protocol helping them go through the radiation treatments without a problem. So, similar to what I’ve occasionally seen reported from supplementation, the protocol might enhance the ability of one’s system to alleviate some of the negative side effects associated with radiation by strengthening the body’s resiliency and natural defenses. Compare High-dose vitamin C and chemotherapy/radiation side effects.

    Calcium Bentonite Clay

    Great (and possibly accurate) claims are being made for Calcium Bentonite Clay as a general detoxifier incl. as a very effective ionizing radiation chelator, to be used both internally and externally (in baths etc.): “You have Calcium Bentonite Clay as your ally. By using Calcium Bentonite Clay as a lifestyle practice, as described in the book Living Clay, [Nature’s Own Miracle Cure, by Perry A. Smith], you will … protect your body from the daily bombardment of radiation…. [R]adioactive material is of a positive charged ion. Calcium Bentonite Clay is a negative charged ion. Simply put, Calcium Bentonite Clay adsorbs and absorbs positive charged ions and you wash them off or pass them through your body. (quoted from ck.pdf).

    One variety of calcium bentonite clay is considered the purest and best (i.e. most effective) available. The price is high but varies greatly among providers (I’ve seen the cheapest offer so far at ebay at 20 pounds for 60US$).

    Algae: Chlorella & Spirulina

    Chlorella … touted as the perfect whole food … has been found to improve the immune system, … detoxify the body … protect against radiation. (from the Vitamin Bible by Earl Mindell)–“In Chernobyl … spirulina was used to help save many children from radiation poisoning. By taking 5 grams of spirulina a day for 45 days, the Institute of Radiation Medicine in Minsk even proved that children on this protocol experienced enhanced immune systems, T-cell counts and reduced radioactivity. Israeli scientists have since treated Chernobyl children with doses of natural beta carotene from Dunaliella algae and proved that it helped normalize their blood chemistry. Chlorella algae, a known immune system builder and heavy metal detoxifier, has also shown radioprotective effects. Because they bind heavy metals, algae should therefore be consumed after exposure to any type of radioactive contamination.” (from–Note that chlorella and spirulina are rather expensive.

    Vitamin C

    Vitamin C (ascorbic acid) in high or mega-doses reportedly “alleviates most of the horrible side effects of radiation therapy” and is also an effective help with chemotherapy treatment. More

    Modifilan, a concentrated brown seaweed extract and
    reportedly a potent radioactive elements chelator

    Excerpted from

    MODIFILAN was developed in Russia by a group of scientists who worked in the State Rehabilitation Institute, where victims of the Chernobyl nuclear catastrophe underwent treatment. The healing qualities of seaweed had been known for centuries [compare The importance of minerals and trace elements], so the Russian government instructed scientists to find an effective and powerful remedy for the radiation poisoning of that particular population. After trying out various forms of algae, one type yielded the best scientific data for this purpose. It was the brown seaweed known as Laminaria japonica, which grows wild in the northern Pacific Ocean off the coast of uninhabited islands far to the east of Russia, known as the Kurils.

    One of the main qualities of Laminaria is its high content of sodium alginates, which are enhanced by the extraction process used to produce MODIFILAN. Alginates are the most effective organic elements that enable the human body to get rid of heavy metals and toxins. Not all “algae” have alginates; blue or green algae do not. According to scientific testing, only this brown seaweed does! The unique methods of extraction, as well as the quality of this seaweed, are key. MODIFILAN has about 50% of the highest quality alginates.

    The low-temperature processing of MODIFILAN causes a sloughing off of the heavy outer fibers of the seaweed, while retaining the essential properties of the plant. This process further enhances its bioavailability, making the Laminaria more digestible. Forty pounds of raw Laminaria are required to make one pound of MODIFILAN. Eating 8 capsules of extract a day provides the same amount of good, organic micro- and macro-elements contained in an entire plate of this nutrient-rich seaweed.
    And, it is not cooked. The oldest Japanese recipes of preparing seaweed tell us to eat seaweed raw, rather than cooked. Modern science affirms that an anti-cancer substance called Fucoidan, as well as beneficial polysaccharides, will break down if the seaweed is cooked. This was determined when studies were performed on the Japanese island of Okinawa, known for its lowest cancer death rate in Japan.

    The Center for Preventive Medicine had 332 subjects in their study. For six months, 158 of the 332 subjects took Modifilan every day. After this time, those who had taken Modifilan had:

    a. Significant shrinking of the lymph glands which had been enlarged
    b. Improved digestive systems
    c. Decrease in the incidence of bronchitis by 29.5%
    d. No side effects

    The Institute of Immunology carried out research on volunteers from the Chernobyl region, who were exposed to radiation and heavy metal poisoning.
    The results of this research showed:
    a. Modifilan is safe to use; is nontoxic and nonallergenic
    b. Modifilan is very effective in preventing the absorption of and
    promoting the excretion of radioactive elements (e.g.
    strontium and radioactive iodine)

    Some volunteers began growing back their hair which had fallen out due to exposure to radioactive elements.
    Results of the research at Biophysical Institute are:

    a. Modifilan is effective in preventing the absorption of and in
    promoting the excretion of radioactive elements (e.g.
    strontium, cesium, and radioactive iodine)
    b. Modifilan works to protect the thyroid glands by decreasing
    the accumulation of radioactive iodine. As a result of this
    research, Modifilan was recommended both as a healing
    and preventive food supplement.

    The State Technical Medical Center concluded upon completion of their research that Modifilan is:

    a. A safe food supplement
    b. Recommended to increase lipid metabolism
    c. Recommended to improve the function of the immune system
    d. Safe to use and has no harmful effects on any bodily functions
    or organs

    At the Cardiovascular Center at the Sakhalin Hospital, patients were given up to ten grams of Modifilan every day for three months. The results showed:

    a. Decrease of cholesterol by 26.5%
    b. Decrease of B-lipoproteins by 25.1%
    c. Decrease of triglycerides by 32.1%

    No negative reactions were found in the kidneys, the liver and other organs. No side effects were found.”

    Since Modifilan is a commercial product, the usual “caveat emptor” is likely to apply. It may be as effective (or perhaps more effective) and a lot cheaper to buy and consume the raw brown Laminaria seaweed itself.

    Enzyme Therapy

    “Enzymes substantially reduce the occurrence of metastases and the recurrence of cancer. They make malignant tissues more sensitive to radiation, and at the same time, reduce pain and other side effects of radiation. When used in conjunction with surgery, they reduce postoperative pain and hemorrhage.” (excerpted from
    Compare Biopsies can spread cancer.


    Do a search for anti-radiation homeopathic remedies, “homeopathic remedy antagonists” etc. (there are both “drainage” and opposing formulas) that are said to work to remedy the harmful effects of ionizing and other radiation (radium, uranium, plutonium).

    Technology’s Curse -Diet for the Atomic Age

    Technology’s Curse: Diet for the Atomic Age is one of the first books to examine this crucial problem and to offer a rational course of action in dealing with low level radioactive pollution. Based upon years of research, the author has collected the medical and scientific data clearly showing that some foods have protective properties which can safeguard us from the effects of this silent threat. The author presents the theories as to how and why these foods and food supplements stave off the effects of radiation and suggests dietary enhancements to maximize certain foods’ protective powers.

    Containing the most up-to-date information drawn from research studies, documented journal articles, and interviews with leading scientific experts.

    “… dealing with the subject of low level radiation exposures … the best book … I have read. It describes the background radiations we are exposed to in daily life. It also describes what can be done to avoid the dangerous effects of long term exposure to higher than normal levels of radiation. The book describes foods which help eliminate radioactive toxins that concentrate in the body and also describes foods to avoid.” (from a reader’s comment)

    Biological, Chemical, and Nuclear Warfare – Protecting Yourself and Your Loved Ones: The Power of Digital Medicine

    by Savely Yurkovsky (Author), William A. Tiller (Foreword)

    “… a remarkable and timely book… showing us relatively simple pathways to protect ourselves …” (William A. Tiller, Professor Emeritus of Materials Science at Stanford University, the foremost authority in the world in the emerging paradigm-breaking field – one of interface of biology and physics)

    “… Recipe for Survival in a world where biological, chemical and nuclear exposure is a real threat. His use of Digital Homeopathy is essential for anyone who truly wants to improve their health and the health of their families from our most common illnesses. … This book delivers more than the title promises. Yes, it does contain detailed, concise, and complete instructions that a layperson (or even a physician) could follow to augment his chance of survival in the event of a biological, chemical, or nuclear attack. …The bonus is a history of homeopathy, the scientific evidence for its validity… Sage lifestyle, health, and environmental advice is also presented, all thoroughly researched and referenced. Highly recommended! (from readers’ comments)


    Cold Distilling Wine—taking Wine and freezing it then adding this to a a salad spinner –adding a handkerchief inside then adding the ice wine into the salad spinner –folding the handkerchief over the ice seal the top and spin this—and what you will have is a ice in the handkerchief and the brandy in the outer end


    Seed Milk

    Utilizing seeds like sesame seed or almonds —blending a tablespoon or 1-2 ounces in water and xanthium gum start of by adding all of this in a blender then add water about 1.4-1/2 cup to start this and allow everything to puree–it will gelatinize initially, then slowly add water as you do this this will then smooth out and continue this til you reach near the top of the blender ( Do not go all the way to the top or it will over flow just go about an inch below the lid–


    APPLE/ BEET/PEPPERMINT Sauce—Adding 2 apples 1 beet and Peppermint water blend til mushed and consume —will assist in colon repair and regulating—will assist in the maintaining the immune system–aid in digestion and elimination


    Making Butter–Adding 1/2 litre of cream ( 33% in Calgary ) in a Vitamix–and set the mixer on low–at the same time using a chop stick to stir counter clock wise while this is going on-taking precautions as not to go to low to hit the blade–adding tumeric or an essential oil in the beginning before wew start the blending ( optional) in about 10 minutes we had Butter


    Making Lugols Iodine–Take 20 oz of water Add 88grams of Potassium iodide- and 44 grams of iodide mix until dissolved–you made the lugols-


    Making a Alkalizer–Taking Baking Soda -1/4 tsp-2 oz of water-magnesium 200mg cap opened and added to the water–Vitamin C 3 grams–Potassium citrate–200mgs-1 drop of lugols iodine –and citric acid 1/4 tsp mix all the ingredients –do the baking soda last–pre mix the minerals and the vitamin C allowing the citric acid to break down the minerals then add the baking soda and stir –soon as there is a fizz then drink—will feel almost instant relief of pain and see that the muscles will be more relaxed–may induce bowel freedom as well.


    Using Essential Oils on food–we took the essential oil of orange and added one drop to a breaded snack–and then was show hw to apply this to other foods as well and how it was safe–


    Open questions on varying topics from Vitamin D overloading to the Negative impact of Fish Oils– to the varying deceptions going on in the health food industry as well as the food industry–as well questions on health issues and what to do



    Araya Works Shop Calgary AB 5-22 11


    Analgesic- Gails Formula

    Making Colloidal Silver

    Coconut Ice Cream



    this is a remedy for removing pest and particualtes that may occur in the skin and can as well be used as an analgesic


    take wax and ad to a glass jar and then set into a pot of water and allow to boil this will melt the wax ( if you wish you can add essential oils to this )——-at the same time heat a bowl as well on the other burner with a barrier underneath ( a pyrex lid with the bowl on top ) this will keep the wax hot when you pour it in—as we have a small sponge to apply the wax—when liquified then ad to the heated bowl and then utiliz have the sponge ( you will need to hold the sponge so the wax can be hot so use caution here and just use half the sponge ) and apply the wax slowly—an spread ver an area—when this is done then re apply a second and third and 4th coat in the same area this will intensify the heat in the area and transfer the essential oil essences as well—allow to dry in the area—when totally dry peel off the wax and examine the hard wax—you may see the particualtes as well as anything else that might be there—this same thing can be applied for a facial and skin rejuvenator


    Analgesic- Gails Formula

    take a pineapple and use either the core or the whole—take it anc chop into a blender 1-1/12 cup add ½ cup of tumeric-1/4 cup of hot paprika ¼ cup of red hot pepper and the skins or the bioflavonoid of a grapefruit or orange or lemon or pomello ( any citrus ) add water if needed to get started ¼ cup –and proceed to blend— when done use in tablespoon increments—should feel instant releif in pain—will definitely keep heart and arteries clear and balanced -anti cancer compounds-may reduce prostate inflammation-may reduce plaque in the brain—liver support-will have antibacterial properties as well


    Making Colloidal Silver

    we will need silver to wires distilled water and 3 -9 volt batteries and a ppm gauge—what we do is connect the baateries together and add the clips to each side and clip the silver and place inside a container of water making sure the prongs do not touch the water—allow for at the least 20 minutes in water—then proceed to test with the ppm meter—this will give you the amount of silver you have made in this solution—this can be made any time and held in use

    Coconut Ice Cream

    what we will need is cocnut milk-cream-maple syrup (– honey or xylitol or stevia ) or plain fruit of choice-and add nutrients that are fat solubile like Cq 10 ( 4-6 caps 30-100mg strength) and herbs for increase preservation or essential oils such as rosemary or thyme ( 1-2 drops ) spices such as cinnamon or nutmeg or cardamon paprika tumeric to give as well colour and antioxidant and health supporting elemnts to the mix and dry ice or a freezer) mix all the components 1cup coconut milk-1/2a cup of cream ( more if you like or less ) ¼ cup of sweetening material—4-6 caps of Vitamin A or Cq 10 or Vitamin D ( make sure they are crushed or pulverized ) or any other Supplement you may want to use—add 1/ tsp of spices of choice ( cinnamon-clove-cardamon-paprika-) add 1-2 drops of rosemary or sage ( anti oxidant effect to keep the fats stable and non toxic within) add essential ol of lemon or organe or any citurus to give the ice cream the flavour you may desire or add the hotter spiced oils such as nutmeg or cardamon or cinnamon or clove again 1-2 drops ( if comboing oils then just use 1 drop of eacch ) when mixed pour ino a container ( pyrex) and allow to freeze or add to a freezer and then consume as desired


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